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Conserved domains on  [gi|1622945054|ref|XP_014995729|]
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cell cycle checkpoint protein RAD17 isoform X2 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
rad24 TIGR00602
checkpoint protein rad24; All proteins in this family for which functions are known are ...
2-641 0e+00

checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 129690 [Multi-domain]  Cd Length: 637  Bit Score: 986.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054   2 NQVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLesskFPARKRGNLSsLEQIYGLENSKESLSENEPWV 81
Cdd:TIGR00602   1 MDVTDWVKPSFDDFLLSSLISTITKWSLSRPTSSHRRKNSPSTD----IHARKRGFLS-LEQDTGLELSSENLDGNEPWV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  82 DKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQggsILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKD 161
Cdd:TIGR00602  76 EKYKPETQHELAVHKKKIEEVETWLKAQVLENAPKR---ILLITGPSGCGKSTTIKILSKELGIQVQEWSNPTLPDFQKN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 162 DFREIFNTESSFHMFpyQSQIAVFKEFLLRATkyNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLR-KYVRIGR 240
Cdd:TIGR00602 153 DHKVTLSLESCFSNF--QSQIEVFSEFLLRAT--NKLQMLGDDLMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGR 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 241 CPLIFVISDSLSGDNNQ-RLLFP------KEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLEL 313
Cdd:TIGR00602 229 CPLVFIITESLEGDNNQrRLLFPaetimnKEILEEPRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPKKTSVEL 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 314 LCQGCSGDIRSAINSLQFSSSKGenNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKIL 393
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS--GSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQALGGKDVSLFLFRALGKIL 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 394 YCKRASLTELDSPRLPSHLSEYERDTLLVEPEEIVEMSHMPGD-LFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGD 472
Cdd:TIGR00602 387 YCKRATLNELDSPRLPSHLSELSRDTLMVGPEEVVEMSHMPGDkTFNLYSHQNYNDFFVEFDDEVKASEFLNFADILSGD 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 473 WNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALF--PDFCLPALCLQTQL 550
Cdd:TIGR00602 467 WNTRSLLREYSTSSARRGVMHSNKARGIAHCQGGKSSFRPLHKPQWFLISKKYRENCLAAKALFkvEDFCLPADCLQTQL 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 551 LPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSTEESLGEPTQATAPETW 630
Cdd:TIGR00602 547 LPYLALDTIPMRNDAQISFIDDLGRLPLKRDFRRLKMEALTDREVGMIDPDSGDEETSFGDDPAVESDSDPSQAAGPETW 626
                         650
                  ....*....|.
gi 1622945054 631 SLPLSQNSASE 641
Cdd:TIGR00602 627 SLPDSDNSLSE 637
 
Name Accession Description Interval E-value
rad24 TIGR00602
checkpoint protein rad24; All proteins in this family for which functions are known are ...
2-641 0e+00

checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129690 [Multi-domain]  Cd Length: 637  Bit Score: 986.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054   2 NQVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLesskFPARKRGNLSsLEQIYGLENSKESLSENEPWV 81
Cdd:TIGR00602   1 MDVTDWVKPSFDDFLLSSLISTITKWSLSRPTSSHRRKNSPSTD----IHARKRGFLS-LEQDTGLELSSENLDGNEPWV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  82 DKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQggsILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKD 161
Cdd:TIGR00602  76 EKYKPETQHELAVHKKKIEEVETWLKAQVLENAPKR---ILLITGPSGCGKSTTIKILSKELGIQVQEWSNPTLPDFQKN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 162 DFREIFNTESSFHMFpyQSQIAVFKEFLLRATkyNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLR-KYVRIGR 240
Cdd:TIGR00602 153 DHKVTLSLESCFSNF--QSQIEVFSEFLLRAT--NKLQMLGDDLMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGR 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 241 CPLIFVISDSLSGDNNQ-RLLFP------KEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLEL 313
Cdd:TIGR00602 229 CPLVFIITESLEGDNNQrRLLFPaetimnKEILEEPRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPKKTSVEL 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 314 LCQGCSGDIRSAINSLQFSSSKGenNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKIL 393
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS--GSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQALGGKDVSLFLFRALGKIL 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 394 YCKRASLTELDSPRLPSHLSEYERDTLLVEPEEIVEMSHMPGD-LFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGD 472
Cdd:TIGR00602 387 YCKRATLNELDSPRLPSHLSELSRDTLMVGPEEVVEMSHMPGDkTFNLYSHQNYNDFFVEFDDEVKASEFLNFADILSGD 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 473 WNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALF--PDFCLPALCLQTQL 550
Cdd:TIGR00602 467 WNTRSLLREYSTSSARRGVMHSNKARGIAHCQGGKSSFRPLHKPQWFLISKKYRENCLAAKALFkvEDFCLPADCLQTQL 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 551 LPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSTEESLGEPTQATAPETW 630
Cdd:TIGR00602 547 LPYLALDTIPMRNDAQISFIDDLGRLPLKRDFRRLKMEALTDREVGMIDPDSGDEETSFGDDPAVESDSDPSQAAGPETW 626
                         650
                  ....*....|.
gi 1622945054 631 SLPLSQNSASE 641
Cdd:TIGR00602 627 SLPDSDNSLSE 637
Rad17 pfam03215
Rad17 P-loop domain;
72-259 1.93e-90

Rad17 P-loop domain;


Pssm-ID: 367398 [Multi-domain]  Cd Length: 186  Bit Score: 279.15  E-value: 1.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  72 ESLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKqggSILLITGPPGCGKTTTIKVLSKEHGIQVQEWI 151
Cdd:pfam03215   1 INDDGGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENAKH---RILLISGPSGCGKSTVIKELSKELGPKYREWS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 152 NPVL---PDFQKDDFREIFNTESSFhmfpyQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTL 228
Cdd:pfam03215  78 NPTSfrsPPNQVTDFRGDCIVNSRF-----LSQMESFSEFELKGARYLVMQKRGKNAQGNKKLILIEDLPNVFHIDTRRF 152
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1622945054 229 HEVLRKYVRIGRC-PLIFVIS--DSLSGDNNQRL 259
Cdd:pfam03215 153 QQVIRQWLYSSEPlPLIICITecEILEGDNNQRK 186
PRK04195 PRK04195
replication factor C large subunit; Provisional
79-491 4.35e-20

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 93.83  E-value: 4.35e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQvLERQPKQGgsiLLITGPPGCGKTTTIKVLSKEHGIQVQEwINpvlpdf 158
Cdd:PRK04195    3 PWVEKYRPKTLSDVVGNEKAKEQLREWIESW-LKGKPKKA---LLLYGPPGVGKTSLAHALANDYGWEVIE-LN------ 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 159 qKDDFReifNTEssfhmfpyqsqiaVFKEFLLRATKYNKLqmlgddLRTDKKIILVEDLPNQFYR-DSHTLHEVLrKYVR 237
Cdd:PRK04195   72 -ASDQR---TAD-------------VIERVAGEAATSGSL------FGARRKLILLDEVDGIHGNeDRGGARAIL-ELIK 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 238 IGRCPLIFVISDSLSgdnnqrlLFPKEIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKTsLELLCQG 317
Cdd:PRK04195  128 KAKQPIILTANDPYD-------PSLRELRNACLM--IEFKRLSTRSIVPVLKRICRKE------GIECDDEA-LKEIAER 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 318 CSGDIRSAINSLQfSSSKGENNLwprkkgmslksdavlskskrrkkpdrvfENQEVQAIGGKDVSLFLFRALGKIL---Y 394
Cdd:PRK04195  192 SGGDLRSAINDLQ-AIAEGYGKL----------------------------TLEDVKTLGRRDREESIFDALDAVFkarN 242
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 395 CKRA--SLTELDsprlpshlseyerdtllVEPEEIVEmshmpgdlfnlYLHQNYIDFFMDIDDIVRASEFLSFADILSG- 471
Cdd:PRK04195  243 ADQAleASYDVD-----------------EDPDDLIE-----------WIDENIPKEYDDPEDIARAYDALSRADIFLGr 294
                         410       420
                  ....*....|....*....|....*
gi 1622945054 472 -----DWntcSLLReYSTSIATRGV 491
Cdd:PRK04195  295 vkrtqNY---DLWR-YASDLMTAGV 315
HLD_clamp_RarA cd18139
helical lid domain of recombination factor protein RarA; Recombination factor RarA ...
281-339 3.92e-09

helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.


Pssm-ID: 350841 [Multi-domain]  Cd Length: 75  Bit Score: 53.40  E-value: 3.92e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622945054 281 PTIMMKFLNRIVTIEANKNGGKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGENN 339
Cdd:cd18139     3 EEDLEKLLKRALEDKERGGDRKVTIDDE-ALELLAEAADGDARSALNLLELAVLSAEED 60
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
119-189 5.41e-07

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 50.11  E-value: 5.41e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945054 119 GSILLITGPPGCGKTTTIKVLSKEHGiqVQEWINPVLPdfqKDDFREIFNTESsfhmFPYQSQIAVFKEFL 189
Cdd:COG4088     4 PMLLILTGPPGSGKTTFAKALAQRLY--AEGIAVALLH---SDDFRRFLVNES----FPKETYEEVVEDVR 65
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
119-142 1.10e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.05  E-value: 1.10e-03
                           10        20
                   ....*....|....*....|....
gi 1622945054  119 GSILLITGPPGCGKTTTIKVLSKE 142
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARE 25
 
Name Accession Description Interval E-value
rad24 TIGR00602
checkpoint protein rad24; All proteins in this family for which functions are known are ...
2-641 0e+00

checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129690 [Multi-domain]  Cd Length: 637  Bit Score: 986.76  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054   2 NQVTDWVDPSFDDFLECRDISTITATSLGVNNSSHRRKNGPSTLesskFPARKRGNLSsLEQIYGLENSKESLSENEPWV 81
Cdd:TIGR00602   1 MDVTDWVKPSFDDFLLSSLISTITKWSLSRPTSSHRRKNSPSTD----IHARKRGFLS-LEQDTGLELSSENLDGNEPWV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  82 DKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKQggsILLITGPPGCGKTTTIKVLSKEHGIQVQEWINPVLPDFQKD 161
Cdd:TIGR00602  76 EKYKPETQHELAVHKKKIEEVETWLKAQVLENAPKR---ILLITGPSGCGKSTTIKILSKELGIQVQEWSNPTLPDFQKN 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 162 DFREIFNTESSFHMFpyQSQIAVFKEFLLRATkyNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLR-KYVRIGR 240
Cdd:TIGR00602 153 DHKVTLSLESCFSNF--QSQIEVFSEFLLRAT--NKLQMLGDDLMTDKKIILVEDLPNQFYRDTRALHEILRwKYVSIGR 228
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 241 CPLIFVISDSLSGDNNQ-RLLFP------KEIQEECSISNISFNPVAPTIMMKFLNRIVTIEANKNGGKITVPDKTSLEL 313
Cdd:TIGR00602 229 CPLVFIITESLEGDNNQrRLLFPaetimnKEILEEPRVSNISFNPIAPTIMKKFLNRIVTIEAKKNGEKIKVPKKTSVEL 308
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 314 LCQGCSGDIRSAINSLQFSSSKGenNLWPRKKGMSLKSDAVLSKSKRRKKPDRVFENQEVQAIGGKDVSLFLFRALGKIL 393
Cdd:TIGR00602 309 LCQGCSGDIRSAINSLQFSSSKS--GSLPIKKRMSTKSDAHASKSKIKGKHSSNNENQEIQALGGKDVSLFLFRALGKIL 386
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 394 YCKRASLTELDSPRLPSHLSEYERDTLLVEPEEIVEMSHMPGD-LFNLYLHQNYIDFFMDIDDIVRASEFLSFADILSGD 472
Cdd:TIGR00602 387 YCKRATLNELDSPRLPSHLSELSRDTLMVGPEEVVEMSHMPGDkTFNLYSHQNYNDFFVEFDDEVKASEFLNFADILSGD 466
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 473 WNTCSLLREYSTSIATRGVIHSNKARGYAHCQGGGSSFRPLHKPQWFLIYKKYRENCLAAKALF--PDFCLPALCLQTQL 550
Cdd:TIGR00602 467 WNTRSLLREYSTSSARRGVMHSNKARGIAHCQGGKSSFRPLHKPQWFLISKKYRENCLAAKALFkvEDFCLPADCLQTQL 546
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 551 LPYLALLTIPMRNQAQISFIQDIGRLPLKRHFGRLKMEALTDREHGMIDPDSGDEAQLNGGHSTEESLGEPTQATAPETW 630
Cdd:TIGR00602 547 LPYLALDTIPMRNDAQISFIDDLGRLPLKRDFRRLKMEALTDREVGMIDPDSGDEETSFGDDPAVESDSDPSQAAGPETW 626
                         650
                  ....*....|.
gi 1622945054 631 SLPLSQNSASE 641
Cdd:TIGR00602 627 SLPDSDNSLSE 637
Rad17 pfam03215
Rad17 P-loop domain;
72-259 1.93e-90

Rad17 P-loop domain;


Pssm-ID: 367398 [Multi-domain]  Cd Length: 186  Bit Score: 279.15  E-value: 1.93e-90
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  72 ESLSENEPWVDKYKPETQHELAVHKKKIEEVETWLKAQVLERQPKqggSILLITGPPGCGKTTTIKVLSKEHGIQVQEWI 151
Cdd:pfam03215   1 INDDGGEQWYEKYKPNCLEQLAVHKRKIKDVQEWLDAMFLENAKH---RILLISGPSGCGKSTVIKELSKELGPKYREWS 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 152 NPVL---PDFQKDDFREIFNTESSFhmfpyQSQIAVFKEFLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTL 228
Cdd:pfam03215  78 NPTSfrsPPNQVTDFRGDCIVNSRF-----LSQMESFSEFELKGARYLVMQKRGKNAQGNKKLILIEDLPNVFHIDTRRF 152
                         170       180       190
                  ....*....|....*....|....*....|....
gi 1622945054 229 HEVLRKYVRIGRC-PLIFVIS--DSLSGDNNQRL 259
Cdd:pfam03215 153 QQVIRQWLYSSEPlPLIICITecEILEGDNNQRK 186
PRK04195 PRK04195
replication factor C large subunit; Provisional
79-491 4.35e-20

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 93.83  E-value: 4.35e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  79 PWVDKYKPETQHELAVHKKKIEEVETWLKAQvLERQPKQGgsiLLITGPPGCGKTTTIKVLSKEHGIQVQEwINpvlpdf 158
Cdd:PRK04195    3 PWVEKYRPKTLSDVVGNEKAKEQLREWIESW-LKGKPKKA---LLLYGPPGVGKTSLAHALANDYGWEVIE-LN------ 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 159 qKDDFReifNTEssfhmfpyqsqiaVFKEFLLRATKYNKLqmlgddLRTDKKIILVEDLPNQFYR-DSHTLHEVLrKYVR 237
Cdd:PRK04195   72 -ASDQR---TAD-------------VIERVAGEAATSGSL------FGARRKLILLDEVDGIHGNeDRGGARAIL-ELIK 127
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 238 IGRCPLIFVISDSLSgdnnqrlLFPKEIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKTsLELLCQG 317
Cdd:PRK04195  128 KAKQPIILTANDPYD-------PSLRELRNACLM--IEFKRLSTRSIVPVLKRICRKE------GIECDDEA-LKEIAER 191
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 318 CSGDIRSAINSLQfSSSKGENNLwprkkgmslksdavlskskrrkkpdrvfENQEVQAIGGKDVSLFLFRALGKIL---Y 394
Cdd:PRK04195  192 SGGDLRSAINDLQ-AIAEGYGKL----------------------------TLEDVKTLGRRDREESIFDALDAVFkarN 242
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 395 CKRA--SLTELDsprlpshlseyerdtllVEPEEIVEmshmpgdlfnlYLHQNYIDFFMDIDDIVRASEFLSFADILSG- 471
Cdd:PRK04195  243 ADQAleASYDVD-----------------EDPDDLIE-----------WIDENIPKEYDDPEDIARAYDALSRADIFLGr 294
                         410       420
                  ....*....|....*....|....*
gi 1622945054 472 -----DWntcSLLReYSTSIATRGV 491
Cdd:PRK04195  295 vkrtqNY---DLWR-YASDLMTAGV 315
HLD_clamp_RarA cd18139
helical lid domain of recombination factor protein RarA; Recombination factor RarA ...
281-339 3.92e-09

helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.


Pssm-ID: 350841 [Multi-domain]  Cd Length: 75  Bit Score: 53.40  E-value: 3.92e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622945054 281 PTIMMKFLNRIVTIEANKNGGKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGENN 339
Cdd:cd18139     3 EEDLEKLLKRALEDKERGGDRKVTIDDE-ALELLAEAADGDARSALNLLELAVLSAEED 60
PRK12402 PRK12402
replication factor C small subunit 2; Reviewed
80-338 3.79e-07

replication factor C small subunit 2; Reviewed


Pssm-ID: 237090 [Multi-domain]  Cd Length: 337  Bit Score: 52.68  E-value: 3.79e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  80 WVDKYKPETQHELAVHkkkiEEVETWLKAQVLERQPKQggsiLLITGPPGCGKTTTIKVLSKE-HGiqvQEWINPvLPDF 158
Cdd:PRK12402    5 WTEKYRPALLEDILGQ----DEVVERLSRAVDSPNLPH----LLVQGPPGSGKTAAVRALARElYG---DPWENN-FTEF 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 159 QKDDF-----REIFNTEsSFHMF------PYQSQIAVFKEFLLRATKYNKLQmlgddlrTDKKIILV---EDLPNQFyrd 224
Cdd:PRK12402   73 NVADFfdqgkKYLVEDP-RFAHFlgtdkrIRSSKIDNFKHVLKEYASYRPLS-------ADYKTILLdnaEALREDA--- 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 225 SHTLHEVLRKYVRIGRcpliFVISDSlsgdNNQRLLFPkeIQEECsiSNISFNPVAPTIMMKFLNRIVTIEanknggKIT 304
Cdd:PRK12402  142 QQALRRIMEQYSRTCR----FIIATR----QPSKLIPP--IRSRC--LPLFFRAPTDDELVDVLESIAEAE------GVD 203
                         250       260       270
                  ....*....|....*....|....*....|....
gi 1622945054 305 VPDKtSLELLCQGCSGDIRSAINSLQFSSSKGEN 338
Cdd:PRK12402  204 YDDD-GLELIAYYAGGDLRKAILTLQTAALAAGE 236
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
119-189 5.41e-07

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 50.11  E-value: 5.41e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945054 119 GSILLITGPPGCGKTTTIKVLSKEHGiqVQEWINPVLPdfqKDDFREIFNTESsfhmFPYQSQIAVFKEFL 189
Cdd:COG4088     4 PMLLILTGPPGSGKTTFAKALAQRLY--AEGIAVALLH---SDDFRRFLVNES----FPKETYEEVVEDVR 65
rfc PRK00440
replication factor C small subunit; Reviewed
76-338 1.11e-05

replication factor C small subunit; Reviewed


Pssm-ID: 234763 [Multi-domain]  Cd Length: 319  Bit Score: 47.95  E-value: 1.11e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  76 ENEPWVDKYKPETQHELAVHkkkiEEVETWLKAQVLERQ-PKqggsiLLITGPPGCGKTTTIKVLSKEhgiqvqewinpV 154
Cdd:PRK00440    3 MEEIWVEKYRPRTLDEIVGQ----EEIVERLKSYVKEKNmPH-----LLFAGPPGTGKTTAALALARE-----------L 62
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 155 LPDFQKDDFREIfNTESsfhmfpyQSQIAV----FKEFLlratkynKLQMLGDdlrTDKKIILVeDLPNQFYRDS-HTLH 229
Cdd:PRK00440   63 YGEDWRENFLEL-NASD-------ERGIDVirnkIKEFA-------RTAPVGG---APFKIIFL-DEADNLTSDAqQALR 123
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 230 EVLRKYVRIGRcpliFVISDSLSgdnnQRLLFPkeIQEECSIsnISFNPVAPTIMMKFLNRIVTIEanknggKITVPDKt 309
Cdd:PRK00440  124 RTMEMYSQNTR----FILSCNYS----SKIIDP--IQSRCAV--FRFSPLKKEAVAERLRYIAENE------GIEITDD- 184
                         250       260
                  ....*....|....*....|....*....
gi 1622945054 310 SLELLCQGCSGDIRSAINSLQFSSSKGEN 338
Cdd:PRK00440  185 ALEAIYYVSEGDMRKAINALQAAAATGKE 213
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
96-142 1.30e-05

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 47.98  E-value: 1.30e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 1622945054  96 KKKIEEVETWLKAQVLERQ---PKQGGSILLiTGPPGCGKTTTIKVLSKE 142
Cdd:COG0464   166 KEELRELVALPLKRPELREeygLPPPRGLLL-YGPPGTGKTLLARALAGE 214
HLD_clamp_RFC cd18140
helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein ...
284-338 1.33e-05

helical lid domain of replication factor C subunit; Replication factor C (RFC) is five-protein clamp loader complex that forms a stable ATP-dependent complex with the sliding clamp, PCNA, which binds specifically to primed DNA. RFC subunits belong to the clamp loader clade of the AAA+ superfamily.


Pssm-ID: 350842 [Multi-domain]  Cd Length: 63  Bit Score: 43.29  E-value: 1.33e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1622945054 284 MMKFLNRIVTIEanknggKITVPDKtSLELLCQGCSGDIRSAINSLQFSSSKGEN 338
Cdd:cd18140     6 IVKRLREICKKE------GVKIDEE-ALEAIAEKSEGDMRKAINDLQAAAAGGGV 53
PLN03025 PLN03025
replication factor C subunit; Provisional
79-142 5.86e-05

replication factor C subunit; Provisional


Pssm-ID: 178596 [Multi-domain]  Cd Length: 319  Bit Score: 45.49  E-value: 5.86e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945054  79 PWVDKYKPETQHELAVHKKKIEevetwlKAQVLERqpkqGGSI--LLITGPPGCGKTTTIKVLSKE 142
Cdd:PLN03025    2 PWVEKYRPTKLDDIVGNEDAVS------RLQVIAR----DGNMpnLILSGPPGTGKTTSILALAHE 57
AAA_18 pfam13238
AAA domain;
123-224 6.85e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 43.19  E-value: 6.85e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 123 LITGPPGCGKTTTIKVLSKEHGIQvqewinpvlpDFQKDDFREIFNTESSFHmfpyqsQIAVFKEFLLRATKYNKLQMLG 202
Cdd:pfam13238   2 LITGTPGVGKTTLAKELSKRLGFG----------DNVRDLALENGLVLGDDP------ETRESKRLDEDKLDRLLDLLEE 65
                          90       100
                  ....*....|....*....|..
gi 1622945054 203 DDLRTDKKIILVEDLPNQFYRD 224
Cdd:pfam13238  66 NAALEEGGNLIIDGHLAELEPE 87
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
92-147 1.23e-04

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 43.04  E-value: 1.23e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945054  92 LAVHKKKIEEVETWLKAQVLERQPKQGgsILLItGPPGCGKTTTIKVLSKEHGIQV 147
Cdd:cd19481     2 KASLREAVEAPRRGSRLRRYGLGLPKG--ILLY-GPPGTGKTLLAKALAGELGLPL 54
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
106-176 1.88e-04

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 42.13  E-value: 1.88e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945054 106 LKAQVLERQPKQGGSILLITGPPGCGKTTTIKVLSKEhgiqVQEWINPVL----PDF-QKDDFREIFNTESSFHMF 176
Cdd:cd00009     6 AIEALREALELPPPKNLLLYGPPGTGKTTLARAIANE----LFRPGAPFLylnaSDLlEGLVVAELFGHFLVRLLF 77
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
122-147 4.96e-04

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 40.65  E-value: 4.96e-04
                          10        20
                  ....*....|....*....|....*.
gi 1622945054 122 LLITGPPGCGKTTTIKVLSKEHGIQV 147
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPF 26
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
119-142 1.10e-03

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.05  E-value: 1.10e-03
                           10        20
                   ....*....|....*....|....
gi 1622945054  119 GSILLITGPPGCGKTTTIKVLSKE 142
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARE 25
DEXSc_RecD-like cd17933
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ...
118-147 1.91e-03

DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.


Pssm-ID: 350691 [Multi-domain]  Cd Length: 155  Bit Score: 39.46  E-value: 1.91e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1622945054 118 GGSILLITGPPGCGKTTTIKVL---SKEHGIQV 147
Cdd:cd17933    11 RNRVSVLTGGAGTGKTTTLKALlaaLEAEGKRV 43
dNK pfam01712
Deoxynucleoside kinase; This family consists of various deoxynucleoside kinases cytidine EC:2. ...
124-182 2.34e-03

Deoxynucleoside kinase; This family consists of various deoxynucleoside kinases cytidine EC:2.7.1.74, guanosine EC:2.7.1.113, adenosine EC:2.7.1.76 and thymidine kinase EC:2.7.1.21 (which also phosphorylates deoxyuridine and deoxycytosine.) These enzymes catalyze the production of deoxynucleotide 5'-monophosphate from a deoxynucleoside. Using ATP and yielding ADP in the process.


Pssm-ID: 396326  Cd Length: 201  Bit Score: 39.61  E-value: 2.34e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622945054 124 ITGPPGCGKTTTIKVLSKEHGIQ-----VQEWINPVLPDFQKDDFREIF--NTESSFHMFPYQSQI 182
Cdd:pfam01712   3 IEGNIGAGKSTLTKILSKRLGFKvfeepVDRWTNPYLDKFYKDPSRWSFalQTYFLNSRFKQQLEA 68
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
96-142 2.47e-03

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 40.25  E-value: 2.47e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 1622945054  96 KKKIEEV-ETWLKAQVLER---QPKQGgsiLLITGPPGCGKTTTIKVLSKE 142
Cdd:COG1223    11 KKKLKLIiKELRRRENLRKfglWPPRK---ILFYGPPGTGKTMLAEALAGE 58
PRK13768 PRK13768
GTPase; Provisional
120-252 2.74e-03

GTPase; Provisional


Pssm-ID: 237498 [Multi-domain]  Cd Length: 253  Bit Score: 39.85  E-value: 2.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 120 SILLITGPPGCGKTTTIKVLSK---EHGIQVQ--------EWInPVLPDFqkdDFREIFNTES---SFHMFPYQSQIAVF 185
Cdd:PRK13768    3 YIVFFLGTAGSGKTTLTKALSDwleEQGYDVAivnldpavEYL-PYTPDF---DVRDYVTAREimkKYGLGPNGALIASV 78
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622945054 186 kEFLLraTKYNKLQMLGDDLRTDkkIILVeDLPNQ---F-YRDSHTlhEVLRKYVRIGRCPLIFVISDSLS 252
Cdd:PRK13768   79 -DLLL--TKADEIKEEIESLDAD--YVLV-DTPGQmelFaFRESGR--KLVERLSGSSKSVVVFLIDAVLA 141
AAA_16 pfam13191
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ...
108-249 3.96e-03

AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 433025 [Multi-domain]  Cd Length: 167  Bit Score: 38.64  E-value: 3.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054 108 AQVLERQPKQGGSILLITGPPGCGKTTTIKVLSKEHGIQvqewinpvlpdfqkddfREIFNTESSFHMFPYQSQIAVFKE 187
Cdd:pfam13191  13 LDALDRVRSGRPPSVLLTGEAGTGKTTLLRELLRALERD-----------------GGYFLRGKCDENLPYSPLLEALTR 75
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622945054 188 FLLRATKYNKLQMLGDDLRTDKKIILVEDLPNQFYRDSHTLHEVLRKYVRIGRC---PLIFVISD 249
Cdd:pfam13191  76 EGLLRQLLDELESSLLEAWRAALLEALAPVPELPGDLAERLLDLLLRLLDLLARgerPLVLVLDD 140
ExeA COG3267
Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, ...
117-139 4.23e-03

Type II secretory pathway ATPase component GspA/ExeA/MshM [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 442498 [Multi-domain]  Cd Length: 261  Bit Score: 39.39  E-value: 4.23e-03
                          10        20
                  ....*....|....*....|...
gi 1622945054 117 QGGSILLITGPPGCGKTTTIKVL 139
Cdd:COG3267    41 QGGGFVVLTGEVGTGKTTLLRRL 63
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
50-194 4.27e-03

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 40.14  E-value: 4.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  50 FPARKRGNLSSLEQIYGLENSKESLSENEPWVDKYkpetqhelaVHKKKIEEVETWLKAqvLERQPkqggsILLITGPPG 129
Cdd:COG1401   168 APEDLSADALAAELSAAEELYSEDLESEDDYLKDL---------LREKFEETLEAFLAA--LKTKK-----NVILAGPPG 231
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622945054 130 CGKTTTIKVLSKEHGIQVQEWIN--PVLPDFQKDDFRE-IFNTESSFHmfpYQSQIAVFKEFLLRATK 194
Cdd:COG1401   232 TGKTYLARRLAEALGGEDNGRIEfvQFHPSWSYEDFLLgYRPSLDEGK---YEPTPGIFLRFCLKAEK 296
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
20-142 4.73e-03

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 39.60  E-value: 4.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622945054  20 DISTITATSLGVNNSSHRRKNGPSTLESSKFPARKRGNLSSLEQIYGLENSKESLSENEPWVDKYKPE-TQHELAVHKKK 98
Cdd:COG1222     7 IDENIKALLALIDALQERLGVELALLLQPVKALELLEEAPALLLNDANLTQKRLGTPRGTAVPAESPDvTFDDIGGLDEQ 86
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1622945054  99 IEE----VETWLK-AQVLER---QPKQGgsILLiTGPPGCGKTTTIKVLSKE 142
Cdd:COG1222    87 IEEireaVELPLKnPELFRKygiEPPKG--VLL-YGPPGTGKTLLAKAVAGE 135
44 PHA02544
clamp loader, small subunit; Provisional
80-147 6.39e-03

clamp loader, small subunit; Provisional


Pssm-ID: 222866 [Multi-domain]  Cd Length: 316  Bit Score: 39.20  E-value: 6.39e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622945054  80 WVDKYKPETQHE--LAVHKKKIeevetwLKAQVlerqpKQGG--SILLITGPPGCGKTTTIKVLSKEHGIQV 147
Cdd:PHA02544   11 WEQKYRPSTIDEciLPAADKET------FKSIV-----KKGRipNMLLHSPSPGTGKTTVAKALCNEVGAEV 71
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
119-140 6.99e-03

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 37.61  E-value: 6.99e-03
                          10        20
                  ....*....|....*....|..
gi 1622945054 119 GSILLITGPPGCGKTTTIKVLS 140
Cdd:cd00267    25 GEIVALVGPNGSGKSTLLRAIA 46
AAA_28 pfam13521
AAA domain;
124-147 9.01e-03

AAA domain;


Pssm-ID: 433278 [Multi-domain]  Cd Length: 164  Bit Score: 37.63  E-value: 9.01e-03
                          10        20
                  ....*....|....*....|....
gi 1622945054 124 ITGPPGCGKTTTIKVLSKEHGIQV 147
Cdd:pfam13521   4 ITGGPSTGKTTLAEALAARFGYPV 27
Fap7 COG1936
Broad-specificity NMP kinase [Nucleotide transport and metabolism];
121-147 9.15e-03

Broad-specificity NMP kinase [Nucleotide transport and metabolism];


Pssm-ID: 441539 [Multi-domain]  Cd Length: 173  Bit Score: 37.49  E-value: 9.15e-03
                          10        20
                  ....*....|....*....|....*..
gi 1622945054 121 ILLITGPPGCGKTTTIKVLSKEHGIQV 147
Cdd:COG1936     2 RIAITGTPGTGKTTVAKLLAERLGLEV 28
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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