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Conserved domains on  [gi|1622909118|ref|XP_014985464|]
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golgin subfamily B member 1 isoform X1 [Macaca mulatta]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1909-2781 1.67e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 1.67e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1909 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1978
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1979 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2051
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2052 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2110
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2111 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2190
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2191 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2262
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2263 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2339
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2340 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2418
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2419 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2498
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2499 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2578
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2579 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2658
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2659 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2734
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118 2735 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2781
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1310-2095 3.94e-19

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 95.91  E-value: 3.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1388
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1389 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1465
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1466 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1534
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1535 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1607
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1608 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1683
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1684 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1761
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1762 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1841
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1842 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1921
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1922 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 2001
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2002 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2068
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909118 2069 ENLAQAVEHRKKAQAELASFKVLLDDT 2095
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 766-1654 2.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  766 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 845
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  846 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 925
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 1005
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1006 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1085
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1086 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1165
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1166 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1238
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1239 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1314
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1315 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1394
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1474
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1554
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1555 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1634
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909118 1635 NEAERIQHVVEAVRQEKQEL 1654
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 193-1027 1.09e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 1.09e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAErklsfhnLQEEMRH 352
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE-------LKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  353 LLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdalkdQNSKLLQDKDEQAVQSAQTIEQLE 432
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE--------RLEARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  433 DQLQ-QKSKEISQFLNRLPLQQHETasQTCFPDVYNEGTQAvtEENIASLQKRVVELENEKGALLLSSIELEELKAENEK 511
Cdd:TIGR02168  428 KKLEeAELKELQAELEELEEELEEL--QEELERLEEALEEL--REELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  512 LSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQL 588
Cdd:TIGR02168  504 FSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  589 QGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDAGVE 668
Cdd:TIGR02168  581 IKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  669 LKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNN 743
Cdd:TIGR02168  654 LVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEEL 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  744 SSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKIEVL 823
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  824 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQT 903
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  904 IEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagli 980
Cdd:TIGR02168  868 IEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------ 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118  981 sKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 1027
Cdd:TIGR02168  942 -QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3196 1.15e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2453 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2529
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2530 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2603
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2604 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2666
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2667 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2730
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2731 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2801
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2802 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2881
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2882 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2961
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2962 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3041
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3042 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3121
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 3122 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3196
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
COG5022 super family cl34868
Myosin heavy chain [General function prediction only];
33-296 9.91e-03

Myosin heavy chain [General function prediction only];


The actual alignment was detected with superfamily member COG5022:

Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 9.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   33 ELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDvqlQQKDEALQEEKKAADNKiKKLKLHAKAKLTSLNKHIE 112
Cdd:COG5022    856 KAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS---SLKLVNLELESEIIELK-KSLSSDLIENLEFKTELIA 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  113 EMKaqggtVLLTEPQSEEQLSKhdkssteeEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMK 192
Cdd:COG5022    932 RLK-----KLLNNIDLEEGPSI--------EYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFK 998

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:COG5022    999 KELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLL 1078

                          250       260
                   ....*....|....*....|....
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQR 296
Cdd:COG5022   1079 DDKQLYQLESTENLLKTINVKDLE 1102
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1909-2781 1.67e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 1.67e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1909 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1978
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1979 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2051
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2052 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2110
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2111 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2190
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2191 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2262
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2263 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2339
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2340 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2418
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2419 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2498
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2499 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2578
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2579 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2658
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2659 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2734
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118 2735 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2781
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1310-2095 3.94e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.91  E-value: 3.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1388
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1389 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1465
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1466 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1534
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1535 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1607
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1608 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1683
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1684 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1761
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1762 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1841
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1842 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1921
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1922 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 2001
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2002 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2068
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909118 2069 ENLAQAVEHRKKAQAELASFKVLLDDT 2095
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 766-1654 2.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  766 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 845
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  846 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 925
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 1005
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1006 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1085
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1086 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1165
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1166 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1238
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1239 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1314
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1315 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1394
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1474
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1554
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1555 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1634
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909118 1635 NEAERIQHVVEAVRQEKQEL 1654
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1314-1861 4.23e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1314 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1393
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1394 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1472
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1473 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1552
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1553 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1631
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1632 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1706
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1707 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1786
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 1787 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1861
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1846-2372 4.79e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 4.79e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1846 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1925
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1926 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 2002
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2003 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2082
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2083 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2158
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2159 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2238
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2239 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2311
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 2312 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2372
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 193-1027 1.09e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 1.09e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAErklsfhnLQEEMRH 352
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE-------LKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  353 LLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdalkdQNSKLLQDKDEQAVQSAQTIEQLE 432
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE--------RLEARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  433 DQLQ-QKSKEISQFLNRLPLQQHETasQTCFPDVYNEGTQAvtEENIASLQKRVVELENEKGALLLSSIELEELKAENEK 511
Cdd:TIGR02168  428 KKLEeAELKELQAELEELEEELEEL--QEELERLEEALEEL--REELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  512 LSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQL 588
Cdd:TIGR02168  504 FSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  589 QGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDAGVE 668
Cdd:TIGR02168  581 IKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  669 LKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNN 743
Cdd:TIGR02168  654 LVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEEL 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  744 SSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKIEVL 823
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  824 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQT 903
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  904 IEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagli 980
Cdd:TIGR02168  868 IEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------ 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118  981 sKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 1027
Cdd:TIGR02168  942 -QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 766-1101 8.48e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 8.48e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  766 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 845
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  846 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 925
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRkLQA 1005
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQ-LEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1006 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSekcvtskcQEIEISLKQTISEKEVELEHIR 1085
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL--------EEEEEALLELLAELLEEAALLE 476

                          330
                   ....*....|....*.
gi 1622909118 1086 KDLEEKMAAEEQLQAL 1101
Cdd:COG1196    477 AALAELLEELAEAAAR 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3196 1.15e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2453 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2529
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2530 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2603
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2604 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2666
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2667 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2730
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2731 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2801
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2802 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2881
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2882 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2961
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2962 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3041
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3042 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3121
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 3122 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3196
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1503-2096 1.18e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1503 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1579
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1580 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1647
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1648 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1727
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1728 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1807
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1808 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1885
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1886 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1965
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1966 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2044
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909118 2045 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2096
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 693-1139 5.52e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  693 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 772
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  773 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 852
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  853 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 925
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 986
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  987 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1061
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1062 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1138
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909118 1139 D 1139
Cdd:pfam15921  763 E 763
PTZ00121 PTZ00121
MAEBL; Provisional
 1911-2536 1.85e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 1.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1911 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1985
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1986 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2065
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2066 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2140
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2141 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2215
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2216 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2295
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2296 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2361
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2362 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2441
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2442 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2510
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909118 2511 AENNKLKEEIRGLRSHMDDLNSENAK 2536
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 63-617 5.10e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   63 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 141
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  142 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEmkefvmmKQQLQEKEELISTLQAQLSQTQAEQAAQLS 221
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL-------EEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  222 SMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILS 301
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  302 QQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAE 381
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  382 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQ 452
Cdd:COG1196    519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  453 QHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREV 532
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  533 SEISIVDDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGE 612
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754


                   ....*
gi 1622909118  613 GIAPI 617
Cdd:COG1196    755 ELPEP 759
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 920-1771 5.31e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 5.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  920 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 998
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  999 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1078
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1079 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1158
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1159 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1238 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1310
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1311 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1382
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1383 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1462
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1463 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1542
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1622
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1623 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1702
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1703 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1771
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1955-2768 1.30e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1955 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2034
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2035 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2114
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2115 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2188
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2189 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2268
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2269 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2346
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2347 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2426
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2427 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2506
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2507 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2576
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2577 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2656
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2657 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2736
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909118 2737 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2768
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PTZ00121 PTZ00121
MAEBL; Provisional
 710-1237 7.55e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 7.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  710 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 787
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  788 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 860
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  861 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 936
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  937 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1016
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1017 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1096
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1097 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1176
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1177 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 352-1132 3.89e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 3.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  352 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 431
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  432 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 491
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  492 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 565
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  566 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 644
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  645 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 718
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  719 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 797
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  798 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 877
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  878 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 954
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  955 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 1034
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1035 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1113
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909118 1114 NQIDLLQAEISENQVIIQK 1132
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2686-2912 9.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2686 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2765
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2766 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFSMDLpeeNSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2845
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAV---RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2846 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2912
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
mukB PRK04863
chromosome partition protein MukB;
2703-3026 1.99e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2703 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2757
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2758 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2819
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2820 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2892
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2893 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2970
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2971 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 3026
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2568-3089 1.44e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2568 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2640
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2641 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2719
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2720 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2781
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2782 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2842
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2843 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2898
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2899 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2970
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2971 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3047
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909118 3048 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3089
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2045-2214 3.47e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2045 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2120
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2121 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2177
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909118 2178 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2214
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
502-1029 8.89e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 8.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  502 LEELKAENEKLSSQiTLLEAQNRIGEADREV-SEISIVDDANKRSSSTEESGQDVLEnTFSQKHKELSVLLLEMKEAQEE 580
Cdd:PRK02224   189 LDQLKAQIEEKEEK-DLHERLNGLESELAELdEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRET 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  581 IAFLKlqlqgKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDtgqnfplmpneeSSLPAVEKEQASTEHQNRTSEEi 660
Cdd:PRK02224   267 IAETE-----REREELAEEVRDLRERLEELEEERDDLLAEAGLDD------------ADAEAVEARREELEDRDEELRD- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  661 SLNDAGVELKSTKQDCDKSLSAVPDigqcHQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNA 740
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADD----LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  741 DNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHnlLTEQIHSLSIEakSKDVK 819
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELrEREAELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  820 IEVLQNELDDVQLQFS------EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEK 893
Cdd:PRK02224   477 VEELEAELEDLEEEVEeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  894 KRDVETLQQTIEEKDQQVTEISFSMTE---------KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVV 964
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAElkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118  965 SGLKQNYDEMspagliSKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKD 1029
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
COG5022 COG5022
Myosin heavy chain [General function prediction only];
33-296 9.91e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 9.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   33 ELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDvqlQQKDEALQEEKKAADNKiKKLKLHAKAKLTSLNKHIE 112
Cdd:COG5022    856 KAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS---SLKLVNLELESEIIELK-KSLSSDLIENLEFKTELIA 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  113 EMKaqggtVLLTEPQSEEQLSKhdkssteeEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMK 192
Cdd:COG5022    932 RLK-----KLLNNIDLEEGPSI--------EYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFK 998

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:COG5022    999 KELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLL 1078

                          250       260
                   ....*....|....*....|....
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQR 296
Cdd:COG5022   1079 DDKQLYQLESTENLLKTINVKDLE 1102
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1909-2781 1.67e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 1.67e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1909 IQEELSRVTKLKETAEEEKDDLE------ERLMNQLAELNGSIGNYCQDVTDAQ----IKNELLESEMKNLKKCVSELEE 1978
Cdd:TIGR02168  160 IFEEAAGISKYKERRKETERKLErtrenlDRLEDILNELERQLKSLERQAEKAErykeLKAELRELELALLVLRLEELRE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1979 EKQQLVKEKTKVESEIR------KEYLEKIQGAQKEPGNKSHAK-ELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2051
Cdd:TIGR02168  240 ELEELQEELKEAEEELEeltaelQELEEKLEELRLEVSELEEEIeELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2052 ALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD---------DTQSEAARVLADNLK------------LK 2110
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEeleaeleelESRLEELEEQLETLRskvaqlelqiasLN 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2111 KELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2190
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2191 TVAQLAAFTKSMSSLQDDRDRV------IDEAKKWERKFSDAIQTKEEEIRLKE--ENCSVLKDQLRQMSIHMEELKINI 2262
Cdd:TIGR02168  480 AERELAQLQARLDSLERLQENLegfsegVKALLKNQSGLSGILGVLSELISVDEgyEAAIEAALGGRLQAVVVENLNAAK 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2263 SRLEHDKQIWESKAqTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQL---TDLSNSLEKC 2339
Cdd:TIGR02168  560 KAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELA 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2340 KeqKENLEGIIRQQEADIQNSKFSYEQletdlQASRELTSRLHEEINMKE-QKMISLLSGKEEAIQVAIAELRQQHDkei 2418
Cdd:TIGR02168  639 K--KLRPGYRIVTLDGDLVRPGGVITG-----GSAKTNSSILERRREIEElEEKIEELEEKIAELEKALAELRKELE--- 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2419 kELENLLSQEeeenivleeenkkavdktnqlmetlnaikkeniqqKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsv 2498
Cdd:TIGR02168  709 -ELEEELEQL-----------------------------------RKELEELSRQISALRKDLARLEAEVEQLEER---- 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2499 ILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleaqlqqnKELKNKYA 2578
Cdd:TIGR02168  749 IAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL--------TLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2579 KLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyhaqLKVKEEELQRLSALLSS 2658
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE---------LEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2659 SQKRITELEEELvcvqKEAAKKVGEIEDK---LKKELKHLHHDAGIMRNETETAEERVAELARDLVEM-EQKLLMVTKEN 2734
Cdd:TIGR02168  892 LRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEaEALENKIEDDE 967

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118 2735 KDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2781
Cdd:TIGR02168  968 EEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1310-2095 3.94e-19

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 95.91  E-value: 3.94e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGL-EIESLKTASHEAEVRAESLQQKLESSQLQ 1388
Cdd:TIGR02169  237 RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeEQLRVKEKIGELEAEIASLERSIAEKERE 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1389 iaglehLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE---RIKQL 1465
Cdd:TIGR02169  317 ------LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAEtrdELKDY 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1466 QVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALK-----------ENKSLQEELSLARDTIEHLTKSLADVESH 1534
Cdd:TIGR02169  391 REKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAgieakineleeEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1535 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEG-------LTEDKEKLVKEIESLKSSKIA 1607
Cdd:TIGR02169  471 LYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgtvaqLGSVGERYATAIEVAAGNRLN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1608 ----ESSEWQEKHKELQKEYEILLQSYENVsNEAERIQHVVEAVRQEKQELYGklrsteANKKETEKQLQEAEKEMEEMK 1683
Cdd:TIGR02169  551 nvvvEDDAVAKEAIELLKRRKAGRATFLPL-NKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1684 EKMRKFAKSKQQ--KILELEEENDRLRAEVHPAGGTAKECMETLLSsnASMKEEVERVKMEYETLSKKFQSLMSEKDSLS 1761
Cdd:TIGR02169  624 LVVEDIEAARRLmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFS--RSEPAELQRLRERLEGLKRELSSLQSELRRIE 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1762 EEVQDLKHQLESnvsKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSlsmstrpacsesvpsensanpavsedvSSHD 1841
Cdd:TIGR02169  702 NRLDELSQELSD---ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS---------------------------SLEQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1842 EINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE 1921
Cdd:TIGR02169  752 EIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1922 TAEEEKDDLEErlmnQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEK 2001
Cdd:TIGR02169  830 YLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2002 IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIR-------------YQEKISALERTVKALEFVQTESQKDLEITK 2068
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipeeelsledVQAELQRVEEEIRALEPVNMLAIQEYEEVL 985

                          810       820
                   ....*....|....*....|....*..
gi 1622909118 2069 ENLAQAVEHRKKAQAELASFKVLLDDT 2095
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1326-2188 8.83e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 8.83e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1326 KEKLELKISSTTSELTkkseevfQLQDQINKQGLEIESLKTASHEAEvRAESLQQKLESSQLQIAGLEhLRELQPELDEL 1405
Cdd:TIGR02168  174 RKETERKLERTRENLD-------RLEDILNELERQLKSLERQAEKAE-RYKELKAELRELELALLVLR-LEELREELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1406 QKLISEKEEDVSYLSGQLREKEAALTKIQTEiieqedlikalHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEEsra 1485
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLE-----------VSELEEEIEELQKELYALANEISRLEQQKQILRER--- 310

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1486 KQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDR 1565
Cdd:TIGR02168  311 LANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1566 SLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESL-KSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVV 1644
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERLQQEIEELlKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1645 EAVRQEKQELYGKLRSTEANKKETEKQLQEaekemeemkekmrkfAKSKQQKILELEEENDRLRAEVHPAGgtakecmeT 1724
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQEN---------------LEGFSEGVKALLKNQSGLSGILGVLS--------E 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1725 LLSSNASMKEEVERVkmeyetLSKKFQSLMSEkdSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTE-EATQSIPG 1803
Cdd:TIGR02168  528 LISVDEGYEAAIEAA------LGGRLQAVVVE--NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDrEILKNIEG 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1804 etedqdslsmsTRPACSESVPSENSANPAVS---EDVSSHDEINNYLQQIDQLK--ERIAGLEEEkQKNKEFSQTLENER 1878
Cdd:TIGR02168  600 -----------FLGVAKDLVKFDPKLRKALSyllGGVLVVDDLDNALELAKKLRpgYRIVTLDGD-LVRPGGVITGGSAK 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1879 NAllSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERlmnqLAELNGSIGNYCQDVTDAQIK 1958
Cdd:TIGR02168  668 TN--SSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKE----LEELSRQISALRKDLARLEAE 741

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1959 NELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIrKEYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKDCI 2037
Cdd:TIGR02168  742 VEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL-AEAEAEIEELEAQIEQlKEELKALREALDELRAELTLLNEEAA 820

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2038 RYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEaarvLADNLKLKKELQSNK 2117
Cdd:TIGR02168  821 NLRERLESLERRIAATE-------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESE----LEALLNERASLEEAL 889

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 2118 ESVKSQMKQKDEDLerrleqaeekhlkekKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2188
Cdd:TIGR02168  890 ALLRSELEELSEEL---------------RELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERL 945
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 766-1654 2.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.20  E-value: 2.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  766 VVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLsieakskdvkievlQNELDDVQLQFSEQSTLIRSLQ 845
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL--------------REELEELQEELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  846 SQLQNKESEvlegaervrhisskveelsqaLSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISfsmtEKMVQL 925
Cdd:TIGR02168  260 AELQELEEK---------------------LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILR----ERLANL 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAglisKEELQHEFDLLKKENEQRKRKLQA 1005
Cdd:TIGR02168  315 ERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAE----LEELESRLEELEEQLETLRSKVAQ 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1006 ALINRKELLQRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIR 1085
Cdd:TIGR02168  391 LELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEEAELKE-------------LQAELEELEEELEELQ 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1086 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASdgdsvALVKETVVISPPGTDSGEH 1165
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK-----ALLKNQSGLSGILGVLSEL 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1166 WKPElEEKILALEKekeQLQKKLQEALTSRKAILKKAQE------KERHLREELKQQKDDYNR-LQEQFDEQSKENENIG 1238
Cdd:TIGR02168  529 ISVD-EGYEAAIEA---ALGGRLQAVVVENLNAAKKAIAflkqneLGRVTFLPLDSIKGTEIQgNDREILKNIEGFLGVA 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1239 DQLRQLQIQVRESIDGKLPSpdqqewCSPTPGLEEplfkATEQHHTQPVLESNLCPD----WPSHSEDASALQGGTSVAQ 1314
Cdd:TIGR02168  605 KDLVKFDPKLRKALSYLLGG------VLVVDDLDN----ALELAKKLRPGYRIVTLDgdlvRPGGVITGGSAKTNSSILE 674

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1315 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEH 1394
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 lrelqpELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHderiKQLQVELCEMKQ 1474
Cdd:TIGR02168  755 ------ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAEL----TLLNEEAANLRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEhltkslADVESHVsaqnKEKDRVLGRLALLQE 1554
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE------SELEALL----NERASLEEALALLRS 894

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1555 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKsSKIAEssewqekhkELQKEYEILLQSYENVS 1634
Cdd:TIGR02168  895 ELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQ-ERLSE---------EYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|
gi 1622909118 1635 NEAERIQHVVEAVRQEKQEL 1654
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 691-1541 2.81e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.81  E-value: 2.81e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  691 QDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTE 769
Cdd:TIGR02168  192 EDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEkLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  770 LRAQVRQLEMNLAEAerQRRFdyesqtahhnllteqiHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQ 849
Cdd:TIGR02168  272 LRLEVSELEEEIEEL--QKEL----------------YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLD 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  850 NKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEK 929
Cdd:TIGR02168  334 ELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL----NNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  930 FSLGVEIKTLKEQLN-LLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALI 1008
Cdd:TIGR02168  410 ERLEDRRERLQQEIEeLLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQA 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1009 NRKELLQRVSRLEEELANLKDQSKKEIPLSE-----SERGEVEEDKEN------KEYSEKCVTSKCQEIEI---SLKQTI 1074
Cdd:TIGR02168  490 RLDSLERLQENLEGFSEGVKALLKNQSGLSGilgvlSELISVDEGYEAaieaalGGRLQAVVVENLNAAKKaiaFLKQNE 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1075 SEKEVELE-------HIRKDLEEKMAAEEQLQALVKEmnqtLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAS--DGDS 1145
Cdd:TIGR02168  570 LGRVTFLPldsikgtEIQGNDREILKNIEGFLGVAKD----LVKFDPKLRKALSYLLGGVLVVDDLDNALELAKklRPGY 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1146 VALVKETVVISPPGTDSGEHWKPELeeKILALEKEKEQLQKKLqEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQE 1225
Cdd:TIGR02168  646 RIVTLDGDLVRPGGVITGGSAKTNS--SILERRREIEELEEKI-EELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1226 QFDEQSKENENIGDQLRQLQIQVRESIDgkLPSPDQQEWCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshsedasa 1305
Cdd:TIGR02168  723 ELSRQISALRKDLARLEAEVEQLEERIA--QLSKELTELEAEIEELEERLEEAEEE------------------------ 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1306 lqggtsVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESS 1385
Cdd:TIGR02168  777 ------LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEEL 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1386 QLQIAGLEH--------LRELQPELDELQKLISEKEEDVSY-------LSGQLREKEAALTKIQTEIIEQEDLIKALHTQ 1450
Cdd:TIGR02168  851 SEDIESLAAeieeleelIEELESELEALLNERASLEEALALlrseleeLSEELRELESKRSELRRELEELREKLAQLELR 930

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1451 L---EMQAKEHDERI-KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALIS----RKEALKENKSLQEELSLARDTIE 1522
Cdd:TIGR02168  931 LeglEVRIDNLQERLsEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvNLAAIEEYEELKERYDFLTAQKE 1010

                          890
                   ....*....|....*....
gi 1622909118 1523 HLTKSLADVESHVSAQNKE 1541
Cdd:TIGR02168 1011 DLTEAKETLEEAIEEIDRE 1029
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1314-2088 3.56e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 92.43  E-value: 3.56e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1314 QIKAQLKEIE-----TEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1388
Cdd:TIGR02168  217 ELKAELRELElallvLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1389 IAGLEH-LRELQPELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQv 1467
Cdd:TIGR02168  297 ISRLEQqKQILRERLANLERQLEELEA-------QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE- 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1468 elcEMKQKPEEIEEESRAKQQiqrklqaaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNK-----EK 1542
Cdd:TIGR02168  369 ---ELESRLEELEEQLETLRS----------KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKkleeaEL 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS-----SKIAESSEWQEKHK 1617
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERlqenlEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1618 ELQKEYEILLQSYENVSNE---------AERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1688
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1689 FAKSKQQKILELEEENDRLRAEVHPAGGTAKeCMETLLSSNA---SMKEEVERVKMEYETLSKKF----------QSLMS 1755
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSYLLGGVL-VVDDLDNALElakKLRPGYRIVTLDGDLVRPGGvitggsaktnSSILE 674

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1756 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1834
Cdd:TIGR02168  675 RRREIEELEEKIEELEEKIAELEKALAELRKELEELeEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSK 754

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1835 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELS 1914
Cdd:TIGR02168  755 ELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1915 RVTKLKETAEEEKDDLEErlmnQLAELNGSIgnycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEI 1994
Cdd:TIGR02168  835 ATERRLEDLEEQIEELSE----DIESLAAEI-------EELEELIEELESELEALLNERASLEEALALLRSELEELSEEL 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1995 RKEylekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2074
Cdd:TIGR02168  904 REL--------------ESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969

                          810
                   ....*....|....*
gi 1622909118 2075 VEHR-KKAQAELASF 2088
Cdd:TIGR02168  970 ARRRlKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2024-2932 4.29e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.96  E-value: 4.29e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2024 EKQQEVKQLQKDC----IRYQEKISALERTVKALEFVQTESQkdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEA 2099
Cdd:TIGR02168  199 ERQLKSLERQAEKaeryKELKAELRELELALLVLRLEELREE--LEELQEELKEAEEELEELTAELQELEEKLEELRLEV 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2100 ARVLADNLKLKKELQSnkesvksqMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2179
Cdd:TIGR02168  277 SELEEEIEELQKELYA--------LANEISRLEQQKQILRER----LANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2180 EIQQVQENLDSTVAQLAAFTKSmssLQDDRDRVIDEAKKWERKFSDAIQTKEEEirlkeencSVLKDQLRQMSIHMEELK 2259
Cdd:TIGR02168  345 KLEELKEELESLEAELEELEAE---LEELESRLEELEEQLETLRSKVAQLELQI--------ASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2260 INISRLEHDKQIWESKAQ-TEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEK 2338
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEeAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2339 CKEQKENLEGIIRQQEADIQNSkfsyEQLETDLQASRELtsrlheeinmkeqkmISLLSGKEEAIQVAIAELRQQ----H 2414
Cdd:TIGR02168  494 LERLQENLEGFSEGVKALLKNQ----SGLSGILGVLSEL---------------ISVDEGYEAAIEAALGGRLQAvvveN 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2415 DKEIKELENLLSQeeeenivleeenkKAVDKTNQLMETL---NAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2491
Cdd:TIGR02168  555 LNAAKKAIAFLKQ-------------NELGRVTFLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYL 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2492 eerhLSVILEKDQLiQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKqlLEAQLQQNK 2571
Cdd:TIGR02168  622 ----LGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEK--IEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2572 ELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQR 2651
Cdd:TIGR02168  695 ELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE--LTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2652 LSALLSSSQKRITELEEElVCVQKEAAKKVGEIEDKLKKELKHLHHDAGimrneteTAEERVAELARDLVEMEQKLLMVT 2731
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQ-IEQLKEELKALREALDELRAELTLLNEEAA-------NLRERLESLERRIAATERRLEDLE 844

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2732 KENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRErhallsettfsmdlpeenslsy 2811
Cdd:TIGR02168  845 EQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE---------------------- 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2812 LEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSfskamasLQNERDHLWNEL-EKFRKSEEGkqrSAAQPATSLAEVQSLKK 2890
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELRLEG-------LEVRIDNLQERLsEEYSLTLEE---AEALENKIEDDEEEARR 972

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909118 2891 AMSSLQNDRDRL-------LKELKNLQQQYLQINQEITELRPLKAQLQE 2932
Cdd:TIGR02168  973 RLKRLENKIKELgpvnlaaIEEYEELKERYDFLTAQKEDLTEAKETLEE 1021
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1840-2537 3.01e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.01e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1840 HDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKL 1919
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1920 KETAEEEKDDLEERLMNQLAELNGS---IGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1996
Cdd:TIGR02168  318 LEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIAS 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1997 EYLE-KIQGAQKEPGNKSHAKELQELLK-EKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTEsqkdLEITKENLAQA 2074
Cdd:TIGR02168  398 LNNEiERLEARLERLEDRRERLQQEIEElLKKLEEAELKELQAELEELEEELEELQEELERLEEA----LEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2075 VEHRKKAQAELASFKVLLDDTQSEAARVL-----ADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK----E 2145
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSLERLQENLEgfsegVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQavvvE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2146 KKNMQEK-LDALRREKVH----LEETI---GEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSL------QDDRDR 2211
Cdd:TIGR02168  554 NLNAAKKaIAFLKQNELGrvtfLPLDSikgTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlvVDDLDN 633

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2212 VIDEAKKW-----------------------ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLE-- 2266
Cdd:TIGR02168  634 ALELAKKLrpgyrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEee 713

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2267 ---------------HDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD 2331
Cdd:TIGR02168  714 leqlrkeleelsrqiSALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ 793

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2332 LSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLlsgkeeaiQVAIAELR 2411
Cdd:TIGR02168  794 LKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL--------AAEIEELE 865

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2412 QQHDKEIKELENLLSQEEEENIVLEEENKKAvdktNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQL 2491
Cdd:TIGR02168  866 ELIEELESELEALLNERASLEEALALLRSEL----EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118 2492 EERhlsvILEKDQLIQEAAAEN-NKLKEEIRGLRSHMDDLNSENAKL 2537
Cdd:TIGR02168  942 QER----LSEEYSLTLEEAEALeNKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2217-2950 3.25e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.80  E-value: 3.25e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2217 KKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDkqiwESKAQTEVQLQQKVCDTLQGENKE 2296
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEE----LEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2297 LLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRE 2376
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2377 LtsrlHEEINMKEQKMISLLSGKEEAIQV---AIAELRQQ---HDKEIKELENLLSQEEEENIVLEEENKKAVDKT---- 2446
Cdd:TIGR02168  359 E----LEELEAELEELESRLEELEEQLETlrsKVAQLELQiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLeeae 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2447 -NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERH---------LSVILEKDQLIQEAAAENNKL 2516
Cdd:TIGR02168  435 lKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELaqlqarldsLERLQENLEGFSEGVKALLKN 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2517 KEEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQ 2595
Cdd:TIGR02168  515 QSGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREIL 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2596 RSSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSAL 2655
Cdd:TIGR02168  595 KNIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL 673

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2656 lsSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENK 2735
Cdd:TIGR02168  674 --ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2736 DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKL 2815
Cdd:TIGR02168  744 QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREA---------------LDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2816 NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaAQPATSLAEVQSLKKAMSSL 2895
Cdd:TIGR02168  809 RAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELE---ELIEELESELEALLNERASL 885

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2896 QNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQE 2950
Cdd:TIGR02168  886 EEALALLRSELEELSEELRELESKRSELR---RELEELREKLAQLELRLEGLEVR 937
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1314-1861 4.23e-15

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 82.29  E-value: 4.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1314 QIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE 1393
Cdd:COG1196    236 ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1394 H-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1472
Cdd:COG1196    316 ErLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1473 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1552
Cdd:COG1196    396 AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1553 QEERDKLitemDRSLLENQSLSGSCESLKLALEGLTED-KEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYE 1631
Cdd:COG1196    476 EAALAEL----LEELAEAAARLLLLLEAEADYEGFLEGvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNI 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1632 NVSNEAERIqhvvEAVRQEKQELYGK-----LRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDR 1706
Cdd:COG1196    552 VVEDDEVAA----AAIEYLKAAKAGRatflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1707 LRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEK 1786
Cdd:COG1196    628 VAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 1787 HDNQMNVTEEATQSIpgETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLE 1861
Cdd:COG1196    708 ELAEAEEERLEEELE--EEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 927-1767 4.41e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.41  E-value: 4.41e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  927 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLkQNYDEmspagliSKEELQHEFDLLKKENEQRKRKLQAA 1006
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAEL-QELEE-------KLEELRLEVSELEEEIEELQKELYAL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1007 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRK 1086
Cdd:TIGR02168  294 ANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE-SLEAELEELEAELEELES 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1087 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvisppGTDSGEHw 1166
Cdd:TIGR02168  373 RLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKEL------QAELEEL- 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1167 KPELEEKILALEKEKEQLqKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLqEQFDEQSKENENIGDQLRQLQI 1246
Cdd:TIGR02168  446 EEELEELQEELERLEEAL-EELREELEEAEQALDAAERELAQLQARLDSLERLQENL-EGFSEGVKALLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1247 QVRESIdgklpspdqqewcSPTPGLEEPLFKATEQHhTQPVLESNLCPDWPSHSEDASALQGGTSVAQIK----AQLKEI 1322
Cdd:TIGR02168  524 VLSELI-------------SVDEGYEAAIEAALGGR-LQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDsikgTEIQGN 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1323 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASH-----EAEVRAESLQQKLESSQLQIAGLEHLRE 1397
Cdd:TIGR02168  590 DREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALElakklRPGYRIVTLDGDLVRPGGVITGGSAKTN 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1398 LQP-----ELDELQKLISEKEEdvsylsgQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELcem 1472
Cdd:TIGR02168  670 SSIlerrrEIEELEEKIEELEE-------KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE--- 739

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1473 kqkpEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALL 1552
Cdd:TIGR02168  740 ----AEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1553 QEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLksskiaessewQEKHKELQKEYEILLqsyen 1632
Cdd:TIGR02168  816 NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL-----------EELIEELESELEALL----- 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1633 vsNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEendRLRAEVH 1712
Cdd:TIGR02168  880 --NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL----EVRIDNLQE---RLSEEYS 950

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1713 PAGGTAKECMETLLSSNASMKEEVERVKM--------------EYETLSKKFQSLMSEKDSLSEEVQDL 1767
Cdd:TIGR02168  951 LTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnlaaieEYEELKERYDFLTAQKEDLTEAKETL 1019
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2127-2964 1.44e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.87  E-value: 1.44e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2127 KDEDLERRLEQAE--EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTV----AQLAAFTK 2200
Cdd:TIGR02168  153 KPEERRAIFEEAAgiSKYKERRKETERKLERTRENLDRLEDILNELERQLKSLERQAEKAERYKELKAelreLELALLVL 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2201 SMSSLQDDRDRVIDEAKKWERKFSDA---IQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQ 2277
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELtaeLQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2278 TEVQLQQKVCDTLQgenkELLSQLEETrhlyhnsQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADI 2357
Cdd:TIGR02168  313 NLERQLEELEAQLE----ELESKLDEL-------AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2358 QNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENivlee 2437
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLERLEDR-------RERLQQEIEELLKKLEEAELKELQAELEELEEEL----- 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2438 enKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilekdqlIQEAAAENNKLK 2517
Cdd:TIGR02168  450 --EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEG------------FSEGVKALLKNQ 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2518 EEIRGLRSHMDDLNSENAKLDAEL-IQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQR 2596
Cdd:TIGR02168  516 SGLSGILGVLSELISVDEGYEAAIeAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILK 595

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2597 SSNALQEEKRDLSKEIESLKVSVS--------------------QLTRQVTALQEEGTLgIYHAQLKVKEEELQRLSALl 2656
Cdd:TIGR02168  596 NIEGFLGVAKDLVKFDPKLRKALSyllggvlvvddldnalelakKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL- 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2657 sSSQKRITELEEELvcvqkeaaKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2736
Cdd:TIGR02168  674 -ERRREIEELEEKI--------EELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ 744

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2737 LTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE-TTFSMDLPEENS-----LS 2810
Cdd:TIGR02168  745 LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAlDELRAELTLLNEeaanlRE 824

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2811 YLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGKQRSAAQPATSLAEVQSLKK 2890
Cdd:TIGR02168  825 RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL---LNERASLEEALALLRSELEELSE 901

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 2891 AMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQE-----YQDKTKTFQIMQEELRQENLSWQHELHQLRME 2964
Cdd:TIGR02168  902 ELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseeYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1350-1934 1.84e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 80.37  E-value: 1.84e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1350 LQDQINKQgleIESLKTashEAEV--RAESLQQKLESSQLQIAGLeHLRELQPELDELQKLISEKEEDVSYLSGQLREKE 1427
Cdd:COG1196    194 ILGELERQ---LEPLER---QAEKaeRYRELKEELKELEAELLLL-KLRELEAELEELEAELEELEAELEELEAELAELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1428 AALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKEN 1507
Cdd:COG1196    267 AELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1508 KSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMdrsllenqslsgscESLKLALEGL 1587
Cdd:COG1196    347 EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--------------EELEEAEEAL 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1588 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKE 1667
Cdd:COG1196    413 LERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAAR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1668 TEKQLQEAEKEMEEMKEKMRKFAKSKQQKILEL----------------EEENDRLRAEVHPAGGTAKECMETLLSSNAS 1731
Cdd:COG1196    493 LLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvavligveaayeaaleAALAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1732 MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQD 1809
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRtlVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1810 SLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKD 1889
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELE--------ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909118 1890 GELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERL 1934
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1846-2372 4.79e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.83  E-value: 4.79e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1846 YLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEE 1925
Cdd:COG1196    230 LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1926 EKDDLE---ERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKI 2002
Cdd:COG1196    310 RRRELEerlEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2003 QGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQ 2082
Cdd:COG1196    390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2083 AELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKN----MQEKLDALRR 2158
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAyeaaLEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2159 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2238
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2239 ENC-------SVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNS 2311
Cdd:COG1196    630 ARLeaalrraVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 2312 QNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2372
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 193-1027 1.09e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.79  E-value: 1.09e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAaqlssmqqvvREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:TIGR02168  213 ERYKELKAELRELELALLVLRLEEL----------REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAErklsfhnLQEEMRH 352
Cdd:TIGR02168  283 IEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE-------LKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  353 LLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQsacdalkdQNSKLLQDKDEQAVQSAQTIEQLE 432
Cdd:TIGR02168  356 LEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE--------RLEARLERLEDRRERLQQEIEELL 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  433 DQLQ-QKSKEISQFLNRLPLQQHETasQTCFPDVYNEGTQAvtEENIASLQKRVVELENEKGALLLSSIELEELKAENEK 511
Cdd:TIGR02168  428 KKLEeAELKELQAELEELEEELEEL--QEELERLEEALEEL--REELEEAEQALDAAERELAQLQARLDSLERLQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  512 LSSQI-TLLEAQNRIGEADREVSEISIVDDANKRSSST--EESGQDVLENTFSQKHKELSVLLlemKEAQEEIAFLKLQL 588
Cdd:TIGR02168  504 FSEGVkALLKNQSGLSGILGVLSELISVDEGYEAAIEAalGGRLQAVVVENLNAAKKAIAFLK---QNELGRVTFLPLDS 580

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  589 QGKRAEEGDHEVLdQKEMKQMEGEGIAPIKMEVFLEDTGQNFplmpneESSLPAVEKEQASTEHQNRTSEEISLNDAGVE 668
Cdd:TIGR02168  581 IKGTEIQGNDREI-LKNIEGFLGVAKDLVKFDPKLRKALSYL------LGGVLVVDDLDNALELAKKLRPGYRIVTLDGD 653

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  669 LKS-----TKQDCDKSLSAvpdigQCHQDELERLKSQILELELNFHKAqeiyEKNLDEKAKEISNLNQLIEEFKKNADNN 743
Cdd:TIGR02168  654 LVRpggviTGGSAKTNSSI-----LERRREIEELEEKIEELEEKIAEL----EKALAELRKELEELEEELEQLRKELEEL 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  744 SSAFTALSEERDQLLAQVKELSvvtelrAQVRQLEMNLAEAERQRrfdyesqtahhNLLTEQIHSLSIEAKSKDVKIEVL 823
Cdd:TIGR02168  725 SRQISALRKDLARLEAEVEQLE------ERIAQLSKELTELEAEI-----------EELEERLEEAEEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  824 QNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQT 903
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEEL 867

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  904 IEEKDQQVTEISF---SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagli 980
Cdd:TIGR02168  868 IEELESELEALLNeraSLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL------ 941

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118  981 sKEELQHEFDLLKKENEQRKRKLQAALinrKELLQRVSRLEEELANL 1027
Cdd:TIGR02168  942 -QERLSEEYSLTLEEAEALENKIEDDE---EEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 330-1041 1.64e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 77.40  E-value: 1.64e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  330 EKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHkaemEEKTSHILSLQKTGQELQSACDALKdq 409
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL----EELRLEVSELEEEIEELQKELYALA-- 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  410 nsKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQtcfpdvynEGTQAVTEENIASLQKRVVELE 489
Cdd:TIGR02168  295 --NEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL--------EEKLEELKEELESLEAELEELE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  490 NEKGALLLSSIELEE-----------LKAENEKLSSQITLLEAQ-NRI-GEADREVSEISIVDDANKRSSSTEESGQ-DV 555
Cdd:TIGR02168  365 AELEELESRLEELEEqletlrskvaqLELQIASLNNEIERLEARlERLeDRRERLQQEIEELLKKLEEAELKELQAElEE 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  556 LENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAE------------------EGDHEVLDQKEMKQMEGEGIAP- 616
Cdd:TIGR02168  445 LEEELEELQEELERLEEALEELREELEEAEQALDAAERElaqlqarldslerlqenlEGFSEGVKALLKNQSGLSGILGv 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  617 ------------IKMEVFLEDTGQNfPLMPNEESSLPAVE--------------------KEQASTEHQNRTSEEISLnD 664
Cdd:TIGR02168  525 lselisvdegyeAAIEAALGGRLQA-VVVENLNAAKKAIAflkqnelgrvtflpldsikgTEIQGNDREILKNIEGFL-G 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  665 AGVELKSTKQDCDKSLSA-------VPDIgqchqDELERLKSQILELELNFHKAQEIY-------------EKNLDEKAK 724
Cdd:TIGR02168  603 VAKDLVKFDPKLRKALSYllggvlvVDDL-----DNALELAKKLRPGYRIVTLDGDLVrpggvitggsaktNSSILERRR 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  725 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQrrfdyesqtahHNLLT 803
Cdd:TIGR02168  678 EIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrKELEELSRQISALRKDLARLEAE-----------VEQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  804 EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEI 883
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  884 AKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRAEEAKKEQVEEDNEV 963
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEEL 899

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118  964 VSGLKQNYDEMSpagliskeELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESE 1041
Cdd:TIGR02168  900 SEELRELESKRS--------ELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEE 969
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 817-1602 3.87e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 75.87  E-value: 3.87e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  817 DVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEvLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEkkRD 896
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLKEKEALERQKEAIE--RQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  897 VETLQQTIEEKDQQVTEISFSMTEKMVQLNE-----------EKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVS 965
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEElnkkikdlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  966 GLKQNYDEMspagLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSK---KEIPLSESER 1042
Cdd:TIGR02169  326 KLEAEIDKL----LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKdyrEKLEKLKREI 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1043 GEVEEDKENKEYSEKCVTSKCQEIEI---SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1119
Cdd:TIGR02169  402 NELKRELDRLQEELQRLSEELADLNAaiaGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRV 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1120 QAEISENQVIIQKL----TTSNTDASDGDSVALVKETVVISPPGTDSgehwkpEL----EEKILALEK-----------E 1180
Cdd:TIGR02169  482 EKELSKLQRELAEAeaqaRASEERVRGGRAVEEVLKASIQGVHGTVA------QLgsvgERYATAIEVaagnrlnnvvvE 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1181 KEQLQKKLQEALTSRKA------ILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKE--NENIGDQLrqlqiqVRESI 1252
Cdd:TIGR02169  556 DDAVAKEAIELLKRRKAgratflPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafKYVFGDTL------VVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1253 DGKLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESN---LCPDWPSHSEDASALQGGTSVAQIK------------A 1317
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEKSGAMTGGSRAPRGGILFsrsEPAELQRLRERLEGLKRELSSLQSElrrienrldelsQ 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1318 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHlRE 1397
Cdd:TIGR02169  710 ELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEA-RL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1398 LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQ---LEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:TIGR02169  789 SHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQridLKEQIKSIEKEIENLNGKKEELEE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGR------ 1548
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEdeeipe 948

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 1549 ----LALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLK 1602
Cdd:TIGR02169  949 eelsLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1173-1996 6.95e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 6.95e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1173 KILALEKEKEQLQKKLQEALTSRKAILKKAQEKErhlrEELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsI 1252
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQI-L 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1253 DGKLPSPDQQEwcsptpgleEPLFKATEQHHTQPVLESNLCPDWPSHSEDASAlqggtSVAQIKAQLKEIETEKEKLELK 1332
Cdd:TIGR02168  308 RERLANLERQL---------EELEAQLEELESKLDELAEELAELEEKLEELKE-----ELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1333 ISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEhLRELQPELDELQKLISEK 1412
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAE-LKELQAELEELEEELEEL 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1413 EEDVSYLSGQLREKEAALTKIQTEIieqedlikalhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEEsrAKQQIQRK 1492
Cdd:TIGR02168  453 QEELERLEEALEELREELEEAEQAL-----------DAAERELAQLQARLDSLERLQENLEGFSEGVKAL--LKNQSGLS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1493 LQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKdrvLGRLAL--LQEERDKLITEMDRSLLEN 1570
Cdd:TIGR02168  520 GILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNE---LGRVTFlpLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1571 QslsgscESLKLALEGLTEDKEKLVKEIESLKS-SKIAES-SEWQEKHKELQKEYEI------LLQSYENVSNEAERIQH 1642
Cdd:TIGR02168  597 I------EGFLGVAKDLVKFDPKLRKALSYLLGgVLVVDDlDNALELAKKLRPGYRIvtldgdLVRPGGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1643 VVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAK---SKQQKILELEEENDRLRAEVhpagGTAK 1719
Cdd:TIGR02168  671 SILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKeleELSRQISALRKDLARLEAEV----EQLE 746

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1720 ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA--TEKHDNQMNVTEEA 1797
Cdd:TIGR02168  747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAelTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1798 TQSIPGETEDQDSLSMSTRPACSESVPSEnSANPAVSEDVSSHDEINnylQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1877
Cdd:TIGR02168  827 ESLERRIAATERRLEDLEEQIEELSEDIE-SLAAEIEELEELIEELE---SELEALLNERASLEEALALLRSELEELSEE 902

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1878 RNALLSQISTKDGELKLLQEEVSKMNL----LNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVT 1953
Cdd:TIGR02168  903 LRELESKRSELRRELEELREKLAQLELrlegLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIK 982

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 1622909118 1954 DAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRK 1996
Cdd:TIGR02168  983 ELGPVNLAAIEEYEELKERYDFLTAQKEDLTEAKETLEEAIEE 1025
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1578-2402 7.19e-13

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 75.09  E-value: 7.19e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1578 ESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE---KHKELQKEYEILLQSYENVSNEAERIQhvveavrQEKQEL 1654
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLE-------QQKQIL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1655 YGKLRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEVhpagGTAKECMETLLSSNASMKE 1734
Cdd:TIGR02168  308 RERLANLERQLEELEAQLEEL------------------ESKLDELAEELAELEEKL----EELKEELESLEAELEELEA 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1735 EVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEA------TEKHDNQMNVTEEATQSIPGETEDQ 1808
Cdd:TIGR02168  366 ELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDrrerlqQEIEELLKKLEEAELKELQAELEEL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1809 DSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL------L 1882
Cdd:TIGR02168  446 EEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLsgilgvL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1883 SQISTKDGELKLLQEEV--------------SKMNLLNQQIQEELSRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnY 1948
Cdd:TIGR02168  526 SELISVDEGYEAAIEAAlggrlqavvvenlnAAKKAIAFLKQNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-V 603

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1949 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHA---------KELQ 2019
Cdd:TIGR02168  604 AKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELE 683

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2020 ELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvlLDDTQSEA 2099
Cdd:TIGR02168  684 EKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTEL 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2100 ARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDK 2179
Cdd:TIGR02168  760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR-EALDELRAELTLLNEEAANLRERLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2180 EIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWerkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELK 2259
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----LNERASLEEALALLRSELEELSEELRELESKRSELR 914

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2260 INISRL-EHDKQIWESKAQTEVQLQQkvcdTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSN---- 2334
Cdd:TIGR02168  915 RELEELrEKLAQLELRLEGLEVRIDN----LQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnla 990

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 2335 SLEKCKEQKENLEgIIRQQEADIQNSKFSYEQLETDLqaSRELTSRLHE---EINMKEQKMISLLSGKEEA 2402
Cdd:TIGR02168  991 AIEEYEELKERYD-FLTAQKEDLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1973-2794 1.26e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 1.26e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1973 VSELEEEKQQLVKEKTKVESEIRKEYL---EKIQGAQKEPGNKSHAKELQELLKEKQQ-EVKQLQKDCIRYQEKISALER 2048
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLiidEKRQQLERLRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2049 TVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELAsfkvllDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKD 2128
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK------DLGEEEQLRVKEKIGELEAEIASLERSIAEK-EREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2129 EDLERRLEQAEE---KHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAF------- 2198
Cdd:TIGR02169  318 EDAEERLAKLEAeidKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYreklekl 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2199 TKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKIN 2261
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSeeladlnaaiagieakiNELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2262 ISRLEhDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESE-------------------- 2321
Cdd:TIGR02169  478 YDRVE-KELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvved 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2322 -----------------------LNILKDQLTDLSNSLEK-CKEQKENLEGIIRQQEadiqnSKFSYEQLETDLQASREL 2377
Cdd:TIGR02169  557 davakeaiellkrrkagratflpLNKMRDERRDLSILSEDgVIGFAVDLVEFDPKYE-----PAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2378 TSRLHEEINM---------KEQKMI--SLLSGKEEAIQVAIAELRQQHDKEIKELENLLsqeeeenivleeenkkavdkt 2446
Cdd:TIGR02169  632 ARRLMGKYRMvtlegelfeKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKREL--------------------- 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2447 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSH 2526
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER-----------LEELEEDLSSLEQEIENVKSE 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2527 MDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKElknkyakleeKLKESEEANEDLQRSSNALQEEKR 2606
Cdd:TIGR02169  760 LKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEE----------EVSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2607 DLSKEIESLKVSVSQLTRQVTALQEE-----GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELvcvqKEAAKKV 2681
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEienlnGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQL----RELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2682 GEIEDKLKKELKHLhhdaGIMRNETETAEERVAELARDLVEMEQKLLMVTKEnKDLTAQIQSFGRSMSSLQNSRDHANEE 2761
Cdd:TIGR02169  906 EELEAQIEKKRKRL----SELKAKLEALEEELSEIEDPKGEDEEIPEEELSL-EDVQAELQRVEEEIRALEPVNMLAIQE 980

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1622909118 2762 LDELKRKYDaslkelaQLKEQQGLLNRERHALL 2794
Cdd:TIGR02169  981 YEEVLKRLD-------ELKEKRAKLEEERKAIL 1006
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1595-2422 5.02e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 5.02e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1595 VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVS---NEAERIQHVVEAVRQ-EKQELYGKLRSTEANKKETEK 1670
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRrerEKAERYQALLKEKREyEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1671 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKF 1750
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1751 QSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnqmnvteeatqsipgetEDQDSLSMSTRPACSESVpsenSAN 1830
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA-------------------ELKEELEDLRAELEEVDK----EFA 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1831 PAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQ 1910
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLA 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1911 EELSRVTKLKETAEEEKDDLEERLMN---QLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEk 1987
Cdd:TIGR02169  462 ADLSKYEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATA- 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1988 tkveseirkeyLEKIQGAQKEP---GNKSHAKELQELLKEKQ---------QEVKQLQKDcIRYQEKISALERTVKALEF 2055
Cdd:TIGR02169  541 -----------IEVAAGNRLNNvvvEDDAVAKEAIELLKRRKagratflplNKMRDERRD-LSILSEDGVIGFAVDLVEF 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2056 VQTESQKDLEITKENLaqAVEHRKKAQAELASFK-VLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErR 2134
Cdd:TIGR02169  609 DPKYEPAFKYVFGDTL--VVEDIEAARRLMGKYRmVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLE-G 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2135 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2214
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIE-------KEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2215 EAKKWERKFSDaIQTKEEEIRLKEENC--SVLKDQLRQMSIHMEELKINISRLE----HDKQIWESKAQTEVQLQQKVcD 2288
Cdd:TIGR02169  759 ELKELEARIEE-LEEDLHKLEEALNDLeaRLSHSRIPEIQAELSKLEEEVSRIEarlrEIEQKLNRLTLEKEYLEKEI-Q 836

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2289 TLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2368
Cdd:TIGR02169  837 ELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKR 916

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2369 TDLQASRELTSRLHEEINMKEQKMISLLS-GKEEAIQVAIAELRQQHDKEIKELE 2422
Cdd:TIGR02169  917 KRLSELKAKLEALEEELSEIEDPKGEDEEiPEEELSLEDVQAELQRVEEEIRALE 971
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 766-1101 8.48e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 8.48e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  766 VVTELRAQVRQLEmnlAEAERQRRFdyesqtahhNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQ 845
Cdd:COG1196    194 ILGELERQLEPLE---RQAEKAERY---------RELKEELKELEAELLLL--KLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  846 SQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQL 925
Cdd:COG1196    260 AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDemspagliskEELQHEFDLLKKENEQRKRkLQA 1005
Cdd:COG1196    336 EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----------ELAEELLEALRAAAELAAQ-LEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1006 ALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSekcvtskcQEIEISLKQTISEKEVELEHIR 1085
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL--------EEEEEALLELLAELLEEAALLE 476

                          330
                   ....*....|....*.
gi 1622909118 1086 KDLEEKMAAEEQLQAL 1101
Cdd:COG1196    477 AALAELLEELAEAAAR 492
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2015-2615 8.85e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 8.85e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2015 AKELQELLKEKQQEVKQLQKDciRYQEKISALERTVKALEfvqtesqkdleitkENLAQAVEHRKKAQAELASFKVLLDD 2094
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR--ELEAELEELEAELEELE--------------AELEELEAELAELEAELEELRLELEE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2095 TQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQV 2172
Cdd:COG1196    279 LELELEEAQAEEYELLAELARLEQDIARLEERRRELEERleELEEELAELEEELEELEEELEELEEELEEAEEELEEAEA 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2173 TLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRvideakkwerkfsdaIQTKEEEIRLKEENCSVLKDQLRQMS 2252
Cdd:COG1196    359 ELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEEL 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2253 IHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDL 2332
Cdd:COG1196    424 EELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2333 SNSLE--KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEInmkEQKMISLLSGKEEAiQVAIAEL 2410
Cdd:COG1196    504 EGFLEgvKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEV---AAAAIEYLKAAKAG-RATFLPL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2411 RQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQ 2490
Cdd:COG1196    580 DKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL----LGRTLVAARLEAALRRAVTLAGRLREVTLEGEG 655

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2491 LEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDsQQKQLLEAQLQQN 2570
Cdd:COG1196    656 GSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEEL-EEEALEEQLEAER 734

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1622909118 2571 KELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESL 2615
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1460-2342 1.04e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 1.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1460 ERIKQLQVELCEMKQKPEEIEEEsRAKQQIQRKLQAALISRK--EALKENKSLQEELSLARDTIEHLTKSLADVESHVSA 1537
Cdd:TIGR02169  184 ENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEgyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1538 QNKEKDRVLGRLALLQEERDKLITEMDRSLLEN-QSLSGSCESLKLALEGLTEDKEKLVKEIESLKSskiaESSEWQEKH 1616
Cdd:TIGR02169  263 LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKiGELEAEIASLERSIAEKERELEDAEERLAKLEA----EIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1617 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQK 1696
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRL 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1697 ILELEEENDRLRAevhpaggtAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVS 1776
Cdd:TIGR02169  419 SEELADLNAAIAG--------IEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1777 KQANLEATEKHDNQMNVTEEATQSIPGETED------QDSLSMSTRPACSESVPSENSANPAVSEDVSShdeinnylqqi 1850
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtvAQLGSVGERYATAIEVAAGNRLNNVVVEDDAV----------- 559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1851 dqLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDL 1930
Cdd:TIGR02169  560 --AKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1931 EERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRkeyleKIQGAQKE 2008
Cdd:TIGR02169  632 ARRLMGKyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR-----RIENRLDE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2009 PgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASF 2088
Cdd:TIGR02169  707 L--SQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2089 KVLLDDTQSEAARVLADnlKLKKELQSNkESVKSQMKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIG 2168
Cdd:TIGR02169  785 EARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE----KEIQELQEQRIDLKEQIKSIEKEIE 857

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2169 EIQVTLNKKDKEIQQVQenldstvAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQL 2248
Cdd:TIGR02169  858 NLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELERK----IEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2249 RQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESElnilK 2326
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELSleDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEE----R 1002

                          890
                   ....*....|....*.
gi 1622909118 2327 DQLTDLSNSLEKCKEQ 2342
Cdd:TIGR02169 1003 KAILERIEEYEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2453-3196 1.15e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 1.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2453 LNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSV---ILEKDQLIQEAAAENNKLKEEIRGLRSHMDD 2529
Cdd:TIGR02168  234 LEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELeeeIEELQKELYALANEISRLEQQKQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2530 LNSENAKLDAELIQYREDLNQVISIKDSQQKQL------LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQE 2603
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAELEEKLeelkeeLESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2604 EKRDLSKEIESLKVSVSQLTRQVTALQEE-----------------GTLGIYHAQLKVKEEELQRLSALLSSSQKRITEL 2666
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEieellkkleeaelkelqAELEELEEELEELQEELERLEEALEELREELEEA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2667 EEELVCVQKEAAKKVGEIED----------------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMV 2730
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSlerlqenlegfsegvkALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2731 TKENKDLTAQIQ---SFGRSMSSLQNSRDHA-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSM 2801
Cdd:TIGR02168  554 NLNAAKKAIAFLkqnELGRVTFLPLDSIKGTeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVD 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2802 DLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpats 2881
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRIVTLDGDLVRPGGVI---TGGSAKTNSSILERRREIEELEEKIEEL----------------- 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2882 LAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQL 2961
Cdd:TIGR02168  690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEE 768

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2962 RMEKSSWEIHERRMKEQYLMAisDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRN 3041
Cdd:TIGR02168  769 RLEEAEEELAEAEAEIEELEA--QIEQLKEELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATER 838

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3042 QLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHcavLEKQVQELQAVSKEKGPLNI 3121
Cdd:TIGR02168  839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSE---LEELSEELRELESKRSELRR 915

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 3122 DvapgapqekngvhRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERDQRVAA-ENALSLAEEQIRRLE 3196
Cdd:TIGR02168  916 E-------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKiEDDEEEARRRLKRLE 978
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1503-2096 1.18e-10

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 67.78  E-value: 1.18e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1503 ALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMD---RSLLENQSLSGSCES 1579
Cdd:PRK03918   163 AYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEkleKEVKELEELKEEIEE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1580 LKLALEGLTEDKEKL---VKEIESLKSSKIAESSEWQEKHKELQ------KEYEIL---LQSYENVSNEAERIQHVVEAV 1647
Cdd:PRK03918   243 LEKELESLEGSKRKLeekIRELEERIEELKKEIEELEEKVKELKelkekaEEYIKLsefYEEYLDELREIEKRLSRLEEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1648 RQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskqQKILELEEENDRLRAEVhpaGGTAKECMETLLS 1727
Cdd:PRK03918   323 INGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY-----EEAKAKKEELERLKKRL---TGLTPEKLEKELE 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1728 SNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQleSNVSKQANLEATEKHdnQMNVTEEATQSIPGETED 1807
Cdd:PRK03918   395 ELEKAKEEIEE---EISKITARIGELKKEIKELKKAIEELKKA--KGKCPVCGRELTEEH--RKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1808 QDSLSMSTRPACSESVPSENSANPavSEDVSSHDEInnyLQQIDQLKERIAG--LEEEKQKNKEFSQTLEnernallsQI 1885
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKK--ESELIKLKEL---AEQLKELEEKLKKynLEELEKKAEEYEKLKE--------KL 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1886 STKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYcqdvtdaqiknELLESE 1965
Cdd:PRK03918   535 IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL-----------EPFYNE 603

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1966 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkEYLEKIQGAQKEPgnkshAKELQELLKE-KQQEVKQLQKDCIRYQEKIS 2044
Cdd:PRK03918   604 YLELKDAEKELEREEKELKKLEEELDKAF--EELAETEKRLEEL-----RKELEELEKKySEEEYEELREEYLELSRELA 676

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909118 2045 ALERTVKALEFVQTESQKDLEITKENLaqavEHRKKAQAELASFKVLLDDTQ 2096
Cdd:PRK03918   677 GLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERVE 724
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 764-1495 1.30e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 1.30e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  764 LSVVTELRAQVRQLEMNLAEAERQ------RRFDYESQTAHHNLLTEQIhSLSIEAKSKDVKIEVlQNELDDVQLQFSEQ 837
Cdd:TIGR02169  229 LKEKEALERQKEAIERQLASLEEEleklteEISELEKRLEEIEQLLEEL-NKKIKDLGEEEQLRV-KEKIGELEAEIASL 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  838 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEisfs 917
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAE---- 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  918 MTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQnydemspagliSKEELQHEFDLLKKENE 997
Cdd:TIGR02169  383 TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-----------KINELEEEKEDKALEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  998 QRKRKLQAALINRKELLQRVSRLEEELANLKD---QSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTI 1074
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKelsKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1075 SEKEvelehiRKDLEEKMAAEEQLQALVKEMNQTLQ-------------------DKTNQIDLLQAEISENQVIIQKLTT 1135
Cdd:TIGR02169  532 SVGE------RYATAIEVAAGNRLNNVVVEDDAVAKeaiellkrrkagratflplNKMRDERRDLSILSEDGVIGFAVDL 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1136 SNTDASDGDSVALV-KETVVIS-----------------------PPGT--------DSGEHWKPELEEKILALEKEKEQ 1183
Cdd:TIGR02169  606 VEFDPKYEPAFKYVfGDTLVVEdieaarrlmgkyrmvtlegelfeKSGAmtggsrapRGGILFSRSEPAELQRLRERLEG 685

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1184 LQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDGKlpsPDQQE 1263
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK---SELKE 762

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1264 WCSPTPGLEEPLFKATEQhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKK 1343
Cdd:TIGR02169  763 LEARIEELEEDLHKLEEA------------------LNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRL 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1344 SEEVFQLQDqinkqglEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQ 1422
Cdd:TIGR02169  825 TLEKEYLEK-------EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 1423 LREKEAALTKIQTEIIEQEDLIKALHTQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQA 1495
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELKAKLEALE----EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 691-1245 2.08e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.08e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  691 QDELERLKSQILELElnfhKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtEL 770
Cdd:COG1196    238 EAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA------RL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  771 RAQVRQLEMNLAEAERQRrfdyESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQN 850
Cdd:COG1196    308 EERRRELEERLEELEEEL----AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  851 KESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEIsfsmTEKMVQLNEEKF 930
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA----AEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  931 SLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEF-------------DLLKKENE 997
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagavavligVEAAYEAA 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  998 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEK 1077
Cdd:COG1196    540 LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1078 EVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisp 1157
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEEL------ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1158 pgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:COG1196    694 -----------ELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762


                   ....*...
gi 1622909118 1238 GDQLRQLQ 1245
Cdd:COG1196    763 EELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2228-2779 2.17e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.17e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2228 QTKEEEIRLKEENCSVLKDQLRQMSIhmEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGENKELLSQLEETRHL 2307
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2308 YHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINM 2387
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2388 KEQKMISLLSgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2467
Cdd:COG1196    370 AEAELAEAEE-ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2468 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN------------------NKLKEEIRGLRSHMDD 2529
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLllleaeadyegflegvkaALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2530 LNSENAKLDAELIQYREDLNQVISIKDSQQ-KQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2608
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVaAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2609 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2688
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2689 KKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2768
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                          570
                   ....*....|.
gi 1622909118 2769 YDASLKELAQL 2779
Cdd:COG1196    769 LERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2059-2670 3.69e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.11  E-value: 3.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2059 ESQKDLEITKENLAQA----VEHRK-----KAQAELAsfkvllddtqsEAARVLADNLKLKK-ELQSNKESVKSQMKQKD 2128
Cdd:COG1196    176 EAERKLEATEENLERLedilGELERqleplERQAEKA-----------ERYRELKEELKELEaELLLLKLRELEAELEEL 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2129 EDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAftksmssLQDD 2208
Cdd:COG1196    245 EAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE-------LEER 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2209 RDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD 2288
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2289 TLQgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLE 2368
Cdd:COG1196    398 LAA-QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2369 TDLQASRELTSRLHEEINMKEQkMISLLSGKEEA------------IQVAIAELRQQHDKEIKELENLLSQEEEENIVLE 2436
Cdd:COG1196    477 AALAELLEELAEAAARLLLLLE-AEADYEGFLEGvkaalllaglrgLAGAVAVLIGVEAAYEAALEAALAAALQNIVVED 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2437 EENKKAV---DKTNQLM----ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEA 2509
Cdd:COG1196    556 DEVAAAAieyLKAAKAGratfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2510 AAENNKLKEEIRGLRSHMDDLNSENAKldaeliqyredlnqvISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEE 2589
Cdd:COG1196    636 LRRAVTLAGRLREVTLEGEGGSAGGSL---------------TGGSRRELLAALLEAEAELEELAERLAEEELELEEALL 700

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2590 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRlsallSSSQKRITELEEE 2669
Cdd:COG1196    701 AEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL-----EELERELERLERE 775


                   .
gi 1622909118 2670 L 2670
Cdd:COG1196    776 I 776
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2178-2949 4.06e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.24  E-value: 4.06e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2178 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERkfSDAIQTKEEEIRLKEencsvLKDQLRQMSIHMEE 2257
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYE-----LLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2258 LKINISRLEhdkqiwESKAQTEVQLQQKVCDTlqGENKELLSQLEEtrHLYHNSQNELAKLESELNILKDQLTDLSNSLE 2337
Cdd:TIGR02169  242 IERQLASLE------EELEKLTEEISELEKRL--EEIEQLLEELNK--KIKDLGEEEQLRVKEKIGELEAEIASLERSIA 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2338 KCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSgKEEAIQVAIAELRQQHDKE 2417
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRA-ELEEVDKEFAETRDELKDY 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2418 IKELENL-----------------LSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQND 2480
Cdd:TIGR02169  391 REKLEKLkreinelkreldrlqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2481 RDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENA---KLDAELIQYRED---------- 2547
Cdd:TIGR02169  471 LYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaag 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2548 --LNQVISIKDSQQKQLLEAQLQQNK----------------------------------ELKNKYAKLEEKLKESEEAN 2591
Cdd:TIGR02169  547 nrLNNVVVEDDAVAKEAIELLKRRKAgratflplnkmrderrdlsilsedgvigfavdlvEFDPKYEPAFKYVFGDTLVV 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2592 EDLQrSSNALQEEKRDLSKEIESLKVS-------VSQLTRQVTALQEEGTLgiyhAQLKVKEEELQRLSALLSSSQKRIT 2664
Cdd:TIGR02169  627 EDIE-AARRLMGKYRMVTLEGELFEKSgamtggsRAPRGGILFSRSEPAEL----QRLRERLEGLKRELSSLQSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2665 ELEEELVCVQKEAAKKVGEIEDklkkelkhlhhDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2744
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEK-----------EIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2745 GRSMSSLQnsrdhanEELDELKRKYDASlkelaQLKEQQGLlnrerhallsettfsmdlpeenslsyLEKLNQQLLSKDE 2824
Cdd:TIGR02169  771 EEDLHKLE-------EALNDLEARLSHS-----RIPEIQAE--------------------------LSKLEEEVSRIEA 812

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2825 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQ----SLKKAMSSLQNDRD 2900
Cdd:TIGR02169  813 RLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEaalrDLESRLGDLKKERD 892

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909118 2901 RLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdktkTFQIMQEELRQ 2949
Cdd:TIGR02169  893 ELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1392-2303 4.23e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.86  E-value: 4.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1392 LEHLRELQPELDELQKLISEKEEDVSYLSGQlREKEAALTKIQTEIIEQEDLIKALhtqlemQAKEHDERIKQLQVELCE 1471
Cdd:TIGR02169  176 LEELEEVEENIERLDLIIDEKRQQLERLRRE-REKAERYQALLKEKREYEGYELLK------EKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1472 MKQKPEEIEEEsraKQQIQRKLQAALISRKEALKENKSLQEELSLA-RDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1550
Cdd:TIGR02169  249 LEEELEKLTEE---ISELEKRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1551 LLQEERDKLITEMdrsllenqslsgsceslklalegltedkEKLVKEIESLKSSKIAesseWQEKHKELQKEYEILLQSY 1630
Cdd:TIGR02169  326 KLEAEIDKLLAEI----------------------------EELEREIEEERKRRDK----LTEEYAELKEELEDLRAEL 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1631 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANkketEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1710
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINELKRE----LDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1711 VhpaggtakECMETLLSSNASMKEEVERvkmEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKhdnq 1790
Cdd:TIGR02169  450 I--------KKQEWKLEQLAADLSKYEQ---ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEE---- 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1791 mnVTEEATQSIPGETEDQDSLSMSTRPACsESVPSENSANPAVSEDVSShdeinnylqqidqlKERIAGLEEEKQKNKEF 1870
Cdd:TIGR02169  515 --VLKASIQGVHGTVAQLGSVGERYATAI-EVAAGNRLNNVVVEDDAVA--------------KEAIELLKRRKAGRATF 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1871 SQTLENERNALLSQISTKDGELKLLqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNY 1948
Cdd:TIGR02169  578 LPLNKMRDERRDLSILSEDGVIGFA------VDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKyrMVTLEGELFEK 651

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1949 CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEylekiqgaqkepgnKSHAKELQELLKEKQQE 2028
Cdd:TIGR02169  652 SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRI--------------ENRLDELSQELSDASRK 717

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2029 VKQLQKDciryqekISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASfkvllddtqseaarvladnlk 2108
Cdd:TIGR02169  718 IGEIEKE-------IEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE--------------------- 769

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2109 lkkelqsnKESVKSQMKQKDEDLERRLEQaeekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2188
Cdd:TIGR02169  770 --------LEEDLHKLEEALNDLEARLSH------SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEI 835

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2189 DSTVAQLAAFTKSMSSLQDDrdrvIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2268
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKE----IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQ 911

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1622909118 2269 KQIWESK-AQTEVQLQqkvcdTLQGENKELLSQLEE 2303
Cdd:TIGR02169  912 IEKKRKRlSELKAKLE-----ALEEELSEIEDPKGE 942
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1312-1785 4.83e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.73  E-value: 4.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1312 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1391
Cdd:COG1196    283 LEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1392 LEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1470
Cdd:COG1196    363 AEEaLLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1471 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSA-----QNKEKDRV 1545
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGvkaalLLAGLRGL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1546 LGRLALLQEERDKLITEmDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEI 1625
Cdd:COG1196    523 AGAVAVLIGVEAAYEAA-LEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1626 LLQSYENVsnEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1705
Cdd:COG1196    602 DLVASDLR--EADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1706 RLRAEVhpaggtakecmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATE 1785
Cdd:COG1196    680 ELEELA-----------ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELL 748
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 693-1139 5.52e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 65.52  E-value: 5.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  693 ELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtelra 772
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK--------- 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  773 qvRQLEMNLAEAERQRRFDYESQTAhhnllteqihslsieakskdVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKE 852
Cdd:pfam15921  389 --REKELSLEKEQNKRLWDRDTGNS--------------------ITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  853 SEVL-------EGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTeKMVQL 925
Cdd:pfam15921  447 ERQMaaiqgknESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEIT-KLRSR 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  926 NEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMS--------PAGLISKEELQ----------- 986
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTqlvgqhgrTAGAMQVEKAQlekeindrrle 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  987 -HEFDLLKKENEQRKRKLQAALINRK-ELLQRVSRLEEELANLKDQSKKEIPL---SESERGEVEEDKENKEYSEKCVTS 1061
Cdd:pfam15921  606 lQEFKILKDKKDAKIRELEARVSDLElEKVKLVNAGSERLRAVKDIKQERDQLlneVKTSRNELNSLSEDYEVLKRNFRN 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1062 KCQEIEIS---LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEIsenQVIIQKLTTSNT 1138
Cdd:pfam15921  686 KSEEMETTtnkLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI---QFLEEAMTNANK 762


                   .
gi 1622909118 1139 D 1139
Cdd:pfam15921  763 E 763
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1997-2866 5.69e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 65.47  E-value: 5.69e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1997 EYLEKIQGAQKEPGN-KSHAKELQELLKEKQQEVKQLQKD---CIRYQEKISALErtvkalEFVQTESQKDLEITKENLA 2072
Cdd:TIGR02169  167 EFDRKKEKALEELEEvEENIERLDLIIDEKRQQLERLRRErekAERYQALLKEKR------EYEGYELLKEKEALERQKE 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2073 QAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKhLKEKKNMQEK 2152
Cdd:TIGR02169  241 AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERS-IAEKERELED 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2153 LDALRREkvhLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEE 2232
Cdd:TIGR02169  320 AEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2233 EIRLKEE---NCSVLKDQLRQMSIHMEELKINISRLEhdKQIWESKAQTEvqlqqkvcdTLQGENKELLSQLEETRHLYH 2309
Cdd:TIGR02169  397 LKREINElkrELDRLQEELQRLSEELADLNAAIAGIE--AKINELEEEKE---------DKALEIKKQEWKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2310 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKenlegiiRQQEADIQNSKFSYEQLETDLQASRELTSRLheeINMKE 2389
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA-------RASEERVRGGRAVEEVLKASIQGVHGTVAQL---GSVGE 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2390 QKMISL---LSGKEEAIQV--------AIAELRQQHD--------KEIKELENLLSQEEEENIVLEEENKKAVDKTNQ-- 2448
Cdd:TIGR02169  536 RYATAIevaAGNRLNNVVVeddavakeAIELLKRRKAgratflplNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEpa 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2449 ---------LMETLNAIKKENIQQKA---QLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLiqeaAAENN 2514
Cdd:TIGR02169  616 fkyvfgdtlVVEDIEAARRLMGKYRMvtlEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGL----KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2515 KLKEEIRGLRSHMDdlnsenakldaELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLeeklkeseeanEDL 2594
Cdd:TIGR02169  692 SLQSELRRIENRLD-----------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-----------SSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2595 QRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2674
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR----LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLT 825

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2675 KEAakkvgEIEDKLKKELKHLHHDAGIMRNETETAEE----RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSS 2750
Cdd:TIGR02169  826 LEK-----EYLEKEIQELQEQRIDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2751 LQNsrdhaneELDELKRKYDASLKELAQLKEQQGLLNRERHALlsETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLS 2830
Cdd:TIGR02169  901 LER-------KIEELEAQIEKKRKRLSELKAKLEALEEELSEI--EDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALE 971

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|...
gi 1622909118 2831 S-------QLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRK 2866
Cdd:TIGR02169  972 PvnmlaiqEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 48-933 7.73e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 7.73e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   48 EDVQERLAYAEQLVVELKDIIRQKDVQLqqkdEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKAQGGTVLLTEPQ 127
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  128 SEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQIstlqaqltqaqAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQA 207
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEI-----------EELQKELYALANEISRLEQQKQILRERLANLERQLE 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  208 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHeeslvgRAQVVDLLQ 287
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL------RSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  288 QELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAEL 367
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  368 ESRYSALEQKHKAEMEEKTShILSLQKTGQELQSACDALKDQNSKLLQD------------KDEQAVQSA--QTIEQLED 433
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGIlgvlselisvdeGYEAAIEAAlgGRLQAVVV 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  434 QLQQKSKEISQFlnrlpLQQHETASQTCFPdvynegtqaVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLS 513
Cdd:TIGR02168  553 ENLNAAKKAIAF-----LKQNELGRVTFLP---------LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  514 SQI--------TLLEAQNRIGEADREVSEISIVDD-ANKRSSSTEESGQDVLeNTFSQKhKELSVLLLEMKEAQEEIAFL 584
Cdd:TIGR02168  619 SYLlggvlvvdDLDNALELAKKLRPGYRIVTLDGDlVRPGGVITGGSAKTNS-SILERR-REIEELEEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  585 KLQLQgkRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpNEESSLPAVEKEQASTEHQNRTSEEISLnd 664
Cdd:TIGR02168  697 EKALA--ELRKELEELEEELEQLRKELEEL--------------------SRQISALRKDLARLEAEVEQLEERIAQL-- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  665 agvelkstkqdcdkslsavpdigqchQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNADNNS 744
Cdd:TIGR02168  753 --------------------------SKELTELEAEIEELEERLEEAEE----ELAEAEAEIEELEAQIEQLKEELKALR 802

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  745 SAFTALSEERDQLLAQvkelsvVTELRAQVRQLEMNLAEAERQRRfDYESQTAHhnlLTEQIHSLSIEAKSKDVKIEVLQ 824
Cdd:TIGR02168  803 EALDELRAELTLLNEE------AANLRERLESLERRIAATERRLE-DLEEQIEE---LSEDIESLAAEIEELEELIEELE 872

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  825 NELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR----DVETL 900
Cdd:TIGR02168  873 SELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLT 952

                          890       900       910
                   ....*....|....*....|....*....|...
gi 1622909118  901 QQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLG 933
Cdd:TIGR02168  953 LEEAEALENKIEDDEEEARRRLKRLENKIKELG 985
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2371-3195 9.15e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 9.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2371 LQASRELTSRLHEEINMKEQKMISLLSG-------KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAV 2443
Cdd:TIGR02168  205 LERQAEKAERYKELKAELRELELALLVLrleelreELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2444 DKTNQLMETLNAIKKENiQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQEAAAENNKLKEEI 2520
Cdd:TIGR02168  285 ELQKELYALANEISRLE-QQKQILR---ERLANLERQLEELEAQLEELESKLDELAEELAELeekLEELKEELESLEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2521 RGLRSHMDDLNSENAKLDAELIQYREDLNQVisikdSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDlQRSSNA 2600
Cdd:TIGR02168  361 EELEAELEELESRLEELEEQLETLRSKVAQL-----ELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK-KLEEAE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2601 LQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtlgiyHAQLKVKEEELQRLSALLSSSQKRITELEEelvcvQKEAAKK 2680
Cdd:TIGR02168  435 LKELQAELEELEEELEELQEELERLEEALEEL------REELEEAEQALDAAERELAQLQARLDSLER-----LQENLEG 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2681 VGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQ---SFGRSMSSLQNSRDH 2757
Cdd:TIGR02168  504 FSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLkqnELGRVTFLPLDSIKG 583

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2758 A-----NEELDELKRKYDASLKELAQLKEQ-QGLLNrerhALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSS 2831
Cdd:TIGR02168  584 TeiqgnDREILKNIEGFLGVAKDLVKFDPKlRKALS----YLLGGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2832 QLedsYNQVQSFSKAMASLQNERDHLWNELEKFrkseegkqrsaaqpatsLAEVQSLKKAMSSLQNDRDRLLKELKNLQQ 2911
Cdd:TIGR02168  660 VI---TGGSAKTNSSILERRREIEELEEKIEEL-----------------EEKIAELEKALAELRKELEELEEELEQLRK 719

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2912 QYLQINQEITELRPLKAQLQEYQDKTkTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAisDKDQQVS 2991
Cdd:TIGR02168  720 ELEELSRQISALRKDLARLEAEVEQL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA--QIEQLKE 796

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2992 HLQNLIRELRSSSSQAQPLKVQYQRQASpetsaspdGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEK 3071
Cdd:TIGR02168  797 ELKALREALDELRAELTLLNEEAANLRE--------RLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELI 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3072 NTLSIQLcdtsqslrenqqhygdllnhcAVLEKQVQELQavskekgplnidvapgapqekngvhrksdpEELREPQQSFS 3151
Cdd:TIGR02168  869 EELESEL---------------------EALLNERASLE------------------------------EALALLRSELE 897

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909118 3152 EAQQQLCNTRQEVNELRKLLEEERDQRVAAENALSLAEEQIRRL 3195
Cdd:TIGR02168  898 ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1076-1932 9.78e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 9.78e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1076 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDAsDGDSVALVKEtvvi 1155
Cdd:TIGR02168  222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL-QKELYALANE---- 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1156 sppgtdsgehwKPELEEKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1235
Cdd:TIGR02168  297 -----------ISRLEQQKQILRERLANLERQLEEL----EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELE 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1236 NIGDQLRQLQIQVREsidgklpspDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASALQGGTSVAQI 1315
Cdd:TIGR02168  362 ELEAELEELESRLEE---------LEEQLETLRSKVAQLELQIASLNNEIERLEARL--------ERLEDRRERLQQEIE 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1316 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiAGLEHL 1395
Cdd:TIGR02168  425 ELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLE---RLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1396 RELQPELDELQKLISEKEEDVSYLSGQLR---EKEAALtkiqtEIIEQEDLIKALHTQLE--MQAKEHDERIKQLQVELC 1470
Cdd:TIGR02168  502 EGFSEGVKALLKNQSGLSGILGVLSELISvdeGYEAAI-----EAALGGRLQAVVVENLNaaKKAIAFLKQNELGRVTFL 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1471 EMKQKPEeieeesrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKD-RVLGRL 1549
Cdd:TIGR02168  577 PLDSIKG---------TEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDNALELAKKlRPGYRI 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1550 ALLQEE---RDKLIT----EMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1622
Cdd:TIGR02168  648 VTLDGDlvrPGGVITggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1623 YEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1702
Cdd:TIGR02168  728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1703 ENDRLRAevhpaggtakecmetLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLE 1782
Cdd:TIGR02168  808 LRAELTL---------------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELE 872

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1783 -ATEKHDNQMNVTEEATQSIpgeTEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAgle 1861
Cdd:TIGR02168  873 sELEALLNERASLEEALALL---RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLS--- 946

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1862 EEKQKNKEFSQTLENERNALLSQIstkDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEE 1932
Cdd:TIGR02168  947 EEYSLTLEEAEALENKIEDDEEEA---RRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1423-1942 1.03e-09

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 64.68  E-value: 1.03e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1423 LREKEAALTKIQTEI--IEQEDLIKALHTqLEMQAKEHDERIKQLQVE---LCEMKQKPEEIEEESRAKQQIQRKLQAAL 1497
Cdd:PRK02224   182 LSDQRGSLDQLKAQIeeKEEKDLHERLNG-LESELAELDEEIERYEEQreqARETRDEADEVLEEHEERREELETLEAEI 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1498 ----ISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSL 1573
Cdd:PRK02224   261 edlrETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAH 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1574 SGSCESLK---LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1650
Cdd:PRK02224   341 NEEAESLRedaDDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1651 KQELYGKLRSTEANKKETEKQLQEAEKEMEE----------MKEKMRKFAKSKQQKILELEEENDRLRAEVhpaggtake 1720
Cdd:PRK02224   421 RDELREREAELEATLRTARERVEEAEALLEAgkcpecgqpvEGSPHVETIEEDRERVEELEAELEDLEEEV--------- 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1721 cmetllssnASMKEEVERVKMEYETlSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANL-EATEKHDNQMNVTEEATQ 1799
Cdd:PRK02224   492 ---------EEVEERLERAEDLVEA-EDRIERLEERREDLEELIAERRETIEEKRERAEELrERAAELEAEAEEKREAAA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1800 SIPGETEDqdslSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEekqknkefsqtLENERN 1879
Cdd:PRK02224   562 EAEEEAEE----AREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAE-----------LNDERR 626

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 1880 ALLSQISTKDGEL--KLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER---LMNQLAELN 1942
Cdd:PRK02224   627 ERLAEKRERKRELeaEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEigaVENELEELE 694
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2489-3060 1.54e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.19  E-value: 1.54e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2489 QQLEERHLSVILEKDQLIQEAAAEnnkLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqQKQLLEAQLQ 2568
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEE---LEAELEELEAELEELEAELAELEAELEELRLELEE--------LELELEEAQA 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2569 QNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEE 2648
Cdd:COG1196    289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE--LEEAEAELAEAEEA 366

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2649 LQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLL 2728
Cdd:COG1196    367 LLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2729 MVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQgllnRERHALLSETTFSMDLPEENS 2808
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAE----ADYEGFLEGVKAALLLAGLRG 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2809 LSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSL 2888
Cdd:COG1196    522 LAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAV 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2889 KKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQDKTK------TFQIMQEELRQENLSWQHELHQLR 2962
Cdd:COG1196    602 DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLegeggsAGGSLTGGSRRELLAALLEAEAEL 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2963 MEKSSWEIHERRMKEQYLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQNLIYETELLRNQ 3042
Cdd:COG1196    682 EELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPD 761

                          570
                   ....*....|....*...
gi 1622909118 3043 LNDSLKEIHQKELRIQQL 3060
Cdd:COG1196    762 LEELERELERLEREIEAL 779
PTZ00121 PTZ00121
MAEBL; Provisional
 1911-2536 1.85e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 64.01  E-value: 1.85e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1911 EELSRVTKLKETAEEEKDDLEER---LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELE--EEKQQLVK 1985
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERnneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKkaEEKKKADE 1306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1986 EKTKVESEIRKEYLEKiqgaqKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLE 2065
Cdd:PTZ00121  1307 AKKKAEEAKKADEAKK-----KAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKAD 1381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2066 ITK---ENLAQAVEHRKKAQAELASFKVLlddTQSEAARVLADNLKLKKELQSNKESVK--SQMKQKDEDLERRLEQAEE 2140
Cdd:PTZ00121  1382 AAKkkaEEKKKADEAKKKAEEDKKKADEL---KKAAAAKKKADEAKKKAEEKKKADEAKkkAEEAKKADEAKKKAEEAKK 1458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2141 -KHLKEKKNMQEKLDALRR---EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD-DRDRVIDE 2215
Cdd:PTZ00121  1459 aEEAKKKAEEAKKADEAKKkaeEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKaEEAKKADE 1538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2216 AKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENK 2295
Cdd:PTZ00121  1539 AKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2296 ----ELLSQLEETRHLYHNSQN----------ELAKLESELNILKDQLTdlsnslEKCKEQKENLEGIiRQQEADIQNSK 2361
Cdd:PTZ00121  1619 kikaEELKKAEEEKKKVEQLKKkeaeekkkaeELKKAEEENKIKAAEEA------KKAEEDKKKAEEA-KKAEEDEKKAA 1691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2362 FSYEQLETDLQASRELTSRLHEEINMKEQkmislLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2441
Cdd:PTZ00121  1692 EALKKEAEEAKKAEELKKKEAEEKKKAEE-----LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEE 1766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2442 AVDKTNQLMETLNAIK----KENIQQKAQLDSFVKSMSSL-------QNDRDRIVGDYQQLEerhlsvilekDQLIQEAA 2510
Cdd:PTZ00121  1767 EKKAEEIRKEKEAVIEeeldEEDEKRRMEVDKKIKDIFDNfaniiegGKEGNLVINDSKEME----------DSAIKEVA 1836

                          650       660
                   ....*....|....*....|....*.
gi 1622909118 2511 AENNKLKEEIRGLRSHMDDLNSENAK 2536
Cdd:PTZ00121  1837 DSKNMQLEEADAFEKHKFNKNNENGE 1862
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1850-2632 2.84e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.16  E-value: 2.84e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1850 IDQLKERIAGLEEEKQKNKEFSQTLE-----------NERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTK 1918
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKekreyegyellKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1919 LKETAEEEKDDLEERLMNQLaelngsignycqdvtdaQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEy 1998
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1999 lekiqgaqkepgnKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEfvqtesqKDLEITKENLAQAVEHR 2078
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD-------KEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2079 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsQMKQKDEDLERRLEQAEEKhlkeKKNMQEKLDALRR 2158
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEWK----LEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2159 EKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRV---IDEAKKWERKFSDAIQT------ 2229
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVaagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2230 -----------KEEEIRLKEENCS--------VLKDQLRQMSIHMEE--LKINISRLEHDKQ-------------IWESK 2275
Cdd:TIGR02169  550 nnvvveddavaKEAIELLKRRKAGratflplnKMRDERRDLSILSEDgvIGFAVDLVEFDPKyepafkyvfgdtlVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2276 AQTEVQLQQKVCDTLQGENKE----LLSQLEETRHLYHNSQNELAKLESelniLKDQLTDLSNSLEKCKEQKENLEGIIR 2351
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgaMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELSSLQSELRRIENRLD 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2352 QQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKmislLSGKEEAIQVAIAELrQQHDKEIKELEnllsqeeee 2431
Cdd:TIGR02169  706 ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEED----LSSLEQEIENVKSEL-KELEARIEELE--------- 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2432 nivleeenkkavDKTNQLMETLNAIKKENIQQkaQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQL---IQE 2508
Cdd:TIGR02169  772 ------------EDLHKLEEALNDLEARLSHS--RIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2509 AAAENNKLKEEIRGLRSHMDDLNSENAKLDAELiqyredlnqvisikdsqqkqlleaqlqqnKELKNKYAKLEEKLKESE 2588
Cdd:TIGR02169  838 LQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL-----------------------------EELEAALRDLESRLGDLK 888

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....
gi 1622909118 2589 EANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEE 2632
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEE 932
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1848-2054 3.60e-09

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 61.70  E-value: 3.60e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1848 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEK 1927
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1928 DDLEERLMNQLAEL--NGSIGNY-----CQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEiRKEYLE 2000
Cdd:COG4942    100 EAQKEELAELLRALyrLGRQPPLalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAE-RAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909118 2001 KIQGAQKEpgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALE 2054
Cdd:COG4942    179 LLAELEEE------RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELE 226
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1841-2615 3.69e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 3.69e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1841 DEINNYLQQIDQLKERIAGLEEEKQKN-KEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEELSRVTKL 1919
Cdd:TIGR02169  265 KRLEEIEQLLEELNKKIKDLGEEEQLRvKEKIGELEAEIASLERSIAEKERELEDAEERLAK---LEAEIDKLLAEIEEL 341

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1920 KETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYL 1999
Cdd:TIGR02169  342 EREIEEERKRRDK-LTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2000 EKIQGAQKEPGNKSHAKELQELLKEKQQEVK-------QLQKDCIRYQEKISALERTVKALEFVQTESQKDLEItKENLA 2072
Cdd:TIGR02169  421 ELADLNAAIAGIEAKINELEEEKEDKALEIKkqewkleQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAE-AEAQA 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2073 QAVEHRkkaQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQ----KDEDL---------ERRLEQAE 2139
Cdd:TIGR02169  500 RASEER---VRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLNnvvvEDDAVakeaiellkRRKAGRAT 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2140 EKHLKEKKNMQEKLDALRREKVHleetigEIQVTLNKKDKEIQQVqenldstVAQLAAFTKSMSSLQDDRDRVID----- 2214
Cdd:TIGR02169  577 FLPLNKMRDERRDLSILSEDGVI------GFAVDLVEFDPKYEPA-------FKYVFGDTLVVEDIEAARRLMGKyrmvt 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2215 -EAKKWERkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWES---KAQTEVQLQQKVCDTL 2290
Cdd:TIGR02169  644 lEGELFEK--SGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENrldELSQELSDASRKIGEI 721

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2291 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFsyEQLETD 2370
Cdd:TIGR02169  722 EKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI--PEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2371 LQASRELTSRLHEEINMKEQKMISLLSGKEEAiqvaiaelrqqhDKEIKELENLLsqeeEENIVLEEENKKAVDKTNQLM 2450
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRLTLEKEYL------------EKEIQELQEQR----IDLKEQIKSIEKEIENLNGKK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2451 ETLNAIKKENIQQKAQLDsfvKSMSSLQNDRDRIVGDYQQLEERhlsvilekdqlIQEAAAENNKLKEEIRGLRSHMDDL 2530
Cdd:TIGR02169  864 EELEEELEELEAALRDLE---SRLGDLKKERDELEAQLRELERK-----------IEELEAQIEKKRKRLSELKAKLEAL 929

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2531 NSENAKLDAELIQYREDLNQVISIKDSQQK-QLLEAQLQQNKELKNKyakLEEKLKESEEANEDLQRSSNALQEEKRDLS 2609
Cdd:TIGR02169  930 EEELSEIEDPKGEDEEIPEEELSLEDVQAElQRVEEEIRALEPVNML---AIQEYEEVLKRLDELKEKRAKLEEERKAIL 1006


                   ....*.
gi 1622909118 2610 KEIESL 2615
Cdd:TIGR02169 1007 ERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 63-617 5.10e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.10e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   63 ELKDIIRQKDVQLQ-QKDEALQEEKKAADNKIKKLKLHAKakltSLNKHIEEMKAQGGTVLLTEPQSEEQLSKHDKSSTE 141
Cdd:COG1196    217 ELKEELKELEAELLlLKLRELEAELEELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAEEYE 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  142 EEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEmkefvmmKQQLQEKEELISTLQAQLSQTQAEQAAQLS 221
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEEL-------EEELEELEEELEEAEEELEEAEAELAEAEE 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  222 SMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESlvgRAQVVDLLQQELTAAEQRNQILS 301
Cdd:COG1196    366 ALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERL---EEELEELEEALAELEEEEEEEEE 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  302 QQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLsfhNLQEEMRHLLEQLEQAGQAQAELESRySALEQKHKAE 381
Cdd:COG1196    443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL---LEELAEAAARLLLLLEAEADYEGFLE-GVKAALLLAG 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  382 MEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAqtIEQLEDQ---------LQQKSKEISQFLNRLPLQ 452
Cdd:COG1196    519 LRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA--IEYLKAAkagratflpLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  453 QHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRIGEADREV 532
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  533 SEISIVDDANKRSSSTEESGQDVLENtfSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEGDHEVLDQKEMKQMEGE 612
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAE--EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754


                   ....*
gi 1622909118  613 GIAPI 617
Cdd:COG1196    755 ELPEP 759
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 920-1771 5.31e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 5.31e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  920 EKMVQLNEEKFSLGVEIKTLKEQ-LNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagLISKEELQHEFDLLKKENEQ 998
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQeLKLKEQAKKALEYYQLKEKLELEEEYLLYLDY----LKLNEERIDLLQELLRDEQE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  999 RKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKE 1078
Cdd:pfam02463  252 EIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1079 VELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPP 1158
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1159 G-TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:pfam02463  412 ElARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLS 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1238 GDQLRQLQIQVRESIDG--KLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDA-----SALQGGT 1310
Cdd:pfam02463  492 RQKLEERSQKESKARSGlkVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEveerqKLVRALT 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1311 SVAQIKAQLKEIETEKEKLELKISSTTSELT--------KKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKL 1382
Cdd:pfam02463  572 ELPLGARKLRLLIPKLKLPLKSIAVLEIDPIlnlaqldkATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKG 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1383 ESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI 1462
Cdd:pfam02463  652 VSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQ 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1463 KQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEK 1542
Cdd:pfam02463  732 DKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 DRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKE 1622
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1623 YEillqsyenvsneaeriqhvvEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEE 1702
Cdd:pfam02463  892 EE--------------------KEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1703 ENDRLRAEVHPAGGTAKEcmETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1771
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAK--EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 935-1535 6.91e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.91e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  935 EIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLQAALINRKELL 1014
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELE----LELEEAQAEEYELLAELARLEQDIARLEERRRELE 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1015 QRVSRLEEELANLKDQSKKEiplsESERGEVEEDKENKEysekcvtskcQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1094
Cdd:COG1196    316 ERLEELEEELAELEEELEEL----EEELEELEEELEEAE----------EELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1095 EEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgehwkpELEEKI 1174
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEE-----------------EEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1175 LALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1254
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1255 klpspdqqewcsptPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASalqggtsvAQIKAQLKEIETEKEKLELKIS 1334
Cdd:COG1196    525 --------------AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAA--------AAIEYLKAAKAGRATFLPLDKI 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1335 STTSELTKKSEEVFQLQDQINKQGLEIEslktASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEE 1414
Cdd:COG1196    583 RARAALAAALARGAIGAAVDLVASDLRE----ADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSA 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1415 DVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelcemkqkpEEIEEESRAKQQIQRKLQ 1494
Cdd:COG1196    659 GGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA----------EAEEERLEEELEEEALEE 728

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909118 1495 AALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1535
Cdd:COG1196    729 QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2310-2781 8.32e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 8.32e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2310 NSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHE--EINM 2387
Cdd:TIGR04523  149 KKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISElkKQNN 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2388 KEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2467
Cdd:TIGR04523  229 QLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDW 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2468 DSFVKSmsSLQNDRDRIVGDYQQLEERHLSVilekdqliqeaaaenNKLKEEIRGLRSHMDDLNSENAKLDAELiqyRED 2547
Cdd:TIGR04523  309 NKELKS--ELKNQEKKLEEIQNQISQNNKII---------------SQLNEQISQLKKELTNSESENSEKQREL---EEK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2548 LNQVISIKDSQQKQLleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVT 2627
Cdd:TIGR04523  369 QNEIEKLKKENQSYK-----QEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIK 443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2628 ALQEEGTlgiyhaqlkVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKlKKELKHLHHDAGIMRNETE 2707
Cdd:TIGR04523  444 DLTNQDS---------VKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSK-EKELKKLNEEKKELEEKVK 513

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 2708 TAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQS--FGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKE 2781
Cdd:TIGR04523  514 DLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQE 589
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1169-1767 1.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1169 ELEEKILALEKEKEQLQKKLQEALTSrkaiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1248
Cdd:COG1196    271 ELRLELEELELELEEAQAEEYELLAE----LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEEL 346

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1249 REsidgklpspdqqewcsptpglEEPLFKATEQHHTQpvlesnlcpdwpshsEDASALQGGTSVAQIKAQLKEIETEKEK 1328
Cdd:COG1196    347 EE---------------------AEEELEEAEAELAE---------------AEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1329 LELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglEHLRELQPELDELQKL 1408
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEA--ELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1409 ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAK-- 1486
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAal 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1487 QQIQRKLQAALISRKEALKENKslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRS 1566
Cdd:COG1196    549 QNIVVEDDEVAAAAIEYLKAAK-------AGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1567 LLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEyeillqsyenvsnEAERIQHVVEA 1646
Cdd:COG1196    622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEA-------------EAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1647 VRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKEcmETLL 1726
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL--EELE 766

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909118 1727 SSNASMKEEVER---VKM----EYETLSKKFQSLMSEKDSLSEEVQDL 1767
Cdd:COG1196    767 RELERLEREIEAlgpVNLlaieEYEELEERYDFLSEQREDLEEARETL 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1843-2347 2.60e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 60.08  E-value: 2.60e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1843 INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNallsQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKET 1922
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEE----LIKEKEKELEEVLREINEISSELPELREELEKLEKEVKE 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1923 AEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQqlVKEKTKVESEIRKEYLEKI 2002
Cdd:PRK03918   233 LEELKEEIEE-LEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKE--KAEEYIKLSEFYEEYLDEL 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2003 QGAQKEPGN-KSHAKELQELLKE---KQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHR 2078
Cdd:PRK03918   310 REIEKRLSRlEEEINGIEERIKEleeKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2079 KKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHL------------KEK 2146
Cdd:PRK03918   390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKA-KGKCPVCGRELTEEHRKELleeytaelkrieKEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2147 KNMQEKLDALRREKVHLE----------------ETIGEIQVTLNKKDKE-IQQVQENLDSTVAQLAAFTKSMSSLQDDR 2209
Cdd:PRK03918   469 KEIEEKERKLRKELRELEkvlkkeseliklkelaEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLKKEL 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2210 DRvIDEAKKWERKFSDAIQTKEEEI-----RLKEENCSVLKD------QLRQMSIHMEELKINISRLEHDKQIWES---- 2274
Cdd:PRK03918   549 EK-LEELKKKLAELEKKLDELEEELaellkELEELGFESVEEleerlkELEPFYNEYLELKDAEKELEREEKELKKleee 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2275 --KAQTEVQLQQKVCDTLQGENKELLSQLEETRH-----LYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLE 2347
Cdd:PRK03918   628 ldKAFEELAETEKRLEELRKELEELEKKYSEEEYeelreEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 563-1253 2.75e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 2.75e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  563 KHKELSVLLLEMKEAQEEIAFLKLQLqgKRAEEGDHEVLDQKEMKQMEGEGIapikmevfledtgqnfplmpneESSLPA 642
Cdd:TIGR02168  223 RELELALLVLRLEELREELEELQEEL--KEAEEELEELTAELQELEEKLEEL----------------------RLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  643 VEKEQAS-TEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYE----- 716
Cdd:TIGR02168  279 LEEEIEElQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEelkee 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  717 -----KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV--------VTELRAQVRQLEMNLAE 783
Cdd:TIGR02168  353 lesleAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlerledrRERLQQEIEELLKKLEE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  784 AERQR-RFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKES------EVL 856
Cdd:TIGR02168  433 AELKElQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGfsegvkALL 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  857 EGAERVRHISSKVEELSQALSQKELEIAK-----MDQLLLEKKRDVETLQQTIEEKDQ-QVTEISFSMTEKMVQLNEEKF 930
Cdd:TIGR02168  513 KNQSGLSGILGVLSELISVDEGYEAAIEAalggrLQAVVVENLNAAKKAIAFLKQNELgRVTFLPLDSIKGTEIQGNDRE 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  931 SLGVEIKTLKEQLNLLSRAEEAKK------------EQVEEDNEVVSGLKQNY-------DEMSPAGLISKEELQHEFDL 991
Cdd:TIGR02168  593 ILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvDDLDNALELAKKLRPGYrivtldgDLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  992 LK-----KENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEI 1066
Cdd:TIGR02168  673 LErrreiEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1067 EISLKQTISEKEVELEHIRKDLEEKMAAE---EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsNTDASDG 1143
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEaeiEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLR--ERLESLE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1144 DSVALVKETVVISPPGTDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI---LKKAQEKERHLREELKQQKDDY 1220
Cdd:TIGR02168  831 RRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLeeaLALLRSELEELSEELRELESKR 910

                          730       740       750
                   ....*....|....*....|....*....|...
gi 1622909118 1221 NRLQEQFDEQSKENENIGDQLRQLQIQVRESID 1253
Cdd:TIGR02168  911 SELRRELEELREKLAQLELRLEGLEVRIDNLQE 943
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1895-2501 3.83e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 3.83e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1895 LQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLmnqlaelngsignycQDVTDAQIKNELLESEMKNLKKCVS 1974
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL---------------REINEISSELPELREELEKLEKEVK 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1975 ELEEEKQ---QLVKEKTKVESEIRKEYlEKIQGAQKEPGNKshaKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVK 2051
Cdd:PRK03918   232 ELEELKEeieELEKELESLEGSKRKLE-EKIRELEERIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLD 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2052 ALEFVQTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLK--KELQSNKESVKSQMKQKD- 2128
Cdd:PRK03918   308 ELREIEKRLSR-LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEeaKAKKEELERLKKRLTGLTp 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2129 EDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLN--KKDKEIQQVQENL---DSTVAQLAAFTKSMS 2203
Cdd:PRK03918   387 EKLEKELEELE----KAKEEIEEEISKITARIGELKKEIKELKKAIEelKKAKGKCPVCGRElteEHRKELLEEYTAELK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2204 SLQDDRDRVIDEAKKWERKFsdaiqTKEEEIRLKEENCSVLKDQLRQMSIHMEELK-INISRLEhdkqiwesKAQTEVQL 2282
Cdd:PRK03918   463 RIEKELKEIEEKERKLRKEL-----RELEKVLKKESELIKLKELAEQLKELEEKLKkYNLEELE--------KKAEEYEK 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2283 QQKVCDTLQGENKELLSQLEETRHLyhnsQNELAKLESELNILKDQLTDLSNSLEKCK-EQKENLEGIIRQQEaDIQNSK 2361
Cdd:PRK03918   530 LKEKLIKLKGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELE-PFYNEY 604

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2362 FSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKE----IKELENLLSQEEEENIVLEE 2437
Cdd:PRK03918   605 LELKDAEKELEREEKELKKLEEELDKAF-EELAETEKRLEELRKELEELEKKYSEEeyeeLREEYLELSRELAGLRAELE 683

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909118 2438 ENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILE 2501
Cdd:PRK03918   684 ELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1323-1986 4.58e-08

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 59.26  E-value: 4.58e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1323 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL-EHLRELQPE 1401
Cdd:TIGR04523   32 DTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1402 LDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEhderIKQLQVELCEMKQKPEEIEE 1481
Cdd:TIGR04523  112 IKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQ----KEELENELNLLEKEKLNIQK 187

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1482 ESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLIT 1561
Cdd:TIGR04523  188 NIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKK 267

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1562 EMDRSLLEnqslsgsCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSewQEKHKELQKEYEILLQSYENVSNEAERIQ 1641
Cdd:TIGR04523  268 QLSEKQKE-------LEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWN--KELKSELKNQEKKLEEIQNQISQNNKIIS 338

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1642 HVVEAVRQEKQELYGKlrstEANKKETEKQLQEaekemeemkekmrkfaksKQQKILELEEENDRLraevhpaggtaKEC 1721
Cdd:TIGR04523  339 QLNEQISQLKKELTNS----ESENSEKQRELEE------------------KQNEIEKLKKENQSY-----------KQE 385

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1722 METLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLeaTEKHDNQMNVTEEATQSI 1801
Cdd:TIGR04523  386 IKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDL--TNQDSVKELIIKNLDNTR 463

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1802 PGETEDQDSLSMSTRPAcsesvpsENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNAL 1881
Cdd:TIGR04523  464 ESLETQLKVLSRSINKI-------KQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEK 536

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1882 LSQISTKDGELKLLQEEVSKMNL------LNQQIQEELSRVTKLKETAEEEKDDLEER------LMNQLAELNGSIGNYC 1949
Cdd:TIGR04523  537 ESKISDLEDELNKDDFELKKENLekeideKNKEIEELKQTQKSLKKKQEEKQELIDQKekekkdLIKEIEEKEKKISSLE 616

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909118 1950 QDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKE 1986
Cdd:TIGR04523  617 KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET 653
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1313-1786 4.78e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 59.31  E-value: 4.78e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1313 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVfqlqDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGL 1392
Cdd:PRK03918   189 ENIEELIKEKEKELEEVLREINEISSELPELREEL----EKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIREL 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1393 E-HLRELQPELDELQKL------ISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQL 1465
Cdd:PRK03918   265 EeRIEELKKEIEELEEKvkelkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIK-ELEEKEERLEEL 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1466 QVELCEMKQKPEEIEEESRAKQQIQRKLqaaliSRKEALKENkslqeelsLARDTIEHLTKSLADVESHVSAQNKEKDRV 1545
Cdd:PRK03918   344 KKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKR--------LTGLTPEKLEKELEELEKAKEEIEEEISKI 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1546 LGRLALLQEErdklITEMDRSLLENQSLSGSCESLKlalEGLTEDKEKLVKEIESLKSSKIA-ESSEWQEKHKELQKEye 1624
Cdd:PRK03918   411 TARIGELKKE----IKELKKAIEELKKAKGKCPVCG---RELTEEHRKELLEEYTAELKRIEkELKEIEEKERKLRKE-- 481

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1625 ilLQSYENVSNEAERIQHVVEAVRQEKqELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEN 1704
Cdd:PRK03918   482 --LRELEKVLKKESELIKLKELAEQLK-ELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKL 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1705 DRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAT 1784
Cdd:PRK03918   559 AELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAET 638


                   ..
gi 1622909118 1785 EK 1786
Cdd:PRK03918   639 EK 640
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1742-2501 9.40e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 58.16  E-value: 9.40e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1742 EYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ--MNVTEEATQSIPGETEDQDSLSMSTRPAC 1819
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkiKDLGEEEQLRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1820 SESVPSENSANPAVSEDVSshdEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEV 1899
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEA---EIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1900 S----KMNLLNQQIQEELSRVTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSE 1975
Cdd:TIGR02169  388 KdyreKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1976 LEEEKQQLVKEKTKVESEIRK---EYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERT-- 2049
Cdd:TIGR02169  467 YEQELYDLKEEYDRVEKELSKlqrELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyATAIEVAag 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2050 --------------VKALEFVQTE---------------SQKDLEITKEN-----LAQAVEHRKKAQAelaSFKVLLDDT 2095
Cdd:TIGR02169  547 nrlnnvvveddavaKEAIELLKRRkagratflplnkmrdERRDLSILSEDgvigfAVDLVEFDPKYEP---AFKYVFGDT 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2096 qseaarVLADNLKLKKELQSNKESV--------KSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETI 2167
Cdd:TIGR02169  624 ------LVVEDIEAARRLMGKYRMVtlegelfeKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSEL 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2168 GEIQvtlnkkdKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQ 2247
Cdd:TIGR02169  698 RRIE-------NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2248 lrQMSIHMEELKINisrlehdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKD 2327
Cdd:TIGR02169  771 --EEDLHKLEEALN--------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2328 QLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKM--ISLLSGKEEAIQV 2405
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIeeLEAQIEKKRKRLS 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2406 AIAELRQQHDKEIKELENLLSQEEEENIVLEEENK--KAVDKTNQLMETLNAIKKENIQQ----KAQLDSFVKSMSSLQN 2479
Cdd:TIGR02169  921 ELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDvqAELQRVEEEIRALEPVNMLAIQEyeevLKRLDELKEKRAKLEE 1000

                          810       820
                   ....*....|....*....|..
gi 1622909118 2480 DRDRIVGDYQQLEERHLSVILE 2501
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREVFME 1022
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1310-1943 1.27e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.82  E-value: 1.27e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQI 1389
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQD--RIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQA 308

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1390 AGLEHLRELQpeldelqklISEKEEDVSYLSGQLREKEAALtkiqteiieqEDLIKALHTQLEMQakehderikqlQVEL 1469
Cdd:pfam15921  309 RNQNSMYMRQ---------LSDLESTVSQLRSELREAKRMY----------EDKIEELEKQLVLA-----------NSEL 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1470 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEAL----KENKSLQEELSLARDTIEHLTKSLADveshvsaQNKEKDRV 1545
Cdd:pfam15921  359 TEARTERDQFSQESGNLDDQLQKLLADLHKREKELslekEQNKRLWDRDTGNSITIDHLRRELDD-------RNMEVQRL 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1546 LgrlALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIA-ESSE---------WQEK 1615
Cdd:pfam15921  432 E---ALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTlESSErtvsdltasLQEK 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1616 HK----------ELQKEYEILLQSYENVSNEAERIQH-----------------VVEAVRQEKQ---ELYGKLRSTEANK 1665
Cdd:pfam15921  509 ERaieatnaeitKLRSRVDLKLQELQHLKNEGDHLRNvqtecealklqmaekdkVIEILRQQIEnmtQLVGQHGRTAGAM 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1666 KETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVERVKMEYET 1745
Cdd:pfam15921  589 QVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELE-----------KVKLVNAGSERLRAVKDIKQERDQ 657

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1746 LSKKFQSLMSEKDSLSEEVQDLKHQLESNVskqanlEATEKHDNQMNVTEEATQSipgETEDQDSLSMSTrpacsesvps 1825
Cdd:pfam15921  658 LLNEVKTSRNELNSLSEDYEVLKRNFRNKS------EEMETTTNKLKMQLKSAQS---ELEQTRNTLKSM---------- 718

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1826 ENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEE--------------EKQKNKEFSQTLENERNALLSQISTKDGE 1891
Cdd:pfam15921  719 EGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEamtnankekhflkeEKNKLSQELSTVATEKNKMAGELEVLRSQ 798

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1622909118 1892 LKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNG 1943
Cdd:pfam15921  799 ERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVKELQG 850
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1955-2768 1.30e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1955 AQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2034
Cdd:pfam02463  179 IEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQ 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2035 DciryQEKISALERTVKALEFVQTESQKdleITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQ 2114
Cdd:pfam02463  259 E----IEKEEEKLAQVLKENKEEEKEKK---LQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELK 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2115 SNKESVKSQMKQKDEDLERRL------EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2188
Cdd:pfam02463  332 KEKEEIEELEKELKELEIKREaeeeeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2189 dstvaQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHD 2268
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2269 KQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK--DQLTDLSNSLEKCKEQKENL 2346
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAisTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2347 EGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS 2426
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKES 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2427 QEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLI 2506
Cdd:pfam02463  647 GLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2507 QEAAAENNKLKEEIR----------GLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNK 2576
Cdd:pfam02463  727 VQEAQDKINEELKLLkqkideeeeeEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRAL 806

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2577 YAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALL 2656
Cdd:pfam02463  807 EEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKD 886

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2657 SSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKD 2736
Cdd:pfam02463  887 ELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLL 966

                          810       820       830
                   ....*....|....*....|....*....|..
gi 1622909118 2737 LTAQIQSFGRSMSSLQNSRDHANEELDELKRK 2768
Cdd:pfam02463  967 LAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1311-1786 1.61e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 57.38  E-value: 1.61e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1311 SVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLKTASHEAEVRAESLQQKLESSQLQIA 1390
Cdd:PRK03918   239 EIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVK----ELKELKEKAEEYIKLSEFYEEYLDELREIEK 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1391 GLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDlIKALHTQLE-MQAKEHDERIKQLQVEL 1469
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEE-AKAKKEELErLKKRLTGLTPEKLEKEL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1470 CEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTI--EHLTKSLADVESHVSAQNKEKDRVLG 1547
Cdd:PRK03918   394 EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELteEHRKELLEEYTAELKRIEKELKEIEE 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1548 RLALLQEERDKLITEM--DRSLLENQSLSGSCESLKLALEGLT-EDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYE 1624
Cdd:PRK03918   474 KERKLRKELRELEKVLkkESELIKLKELAEQLKELEEKLKKYNlEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE 553

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1625 IllqsyenvSNEAERIQHVVEAVRQEKQELYGKLRSTE-ANKKETEKQLQEAEKEMEE--MKEKMRKFAKSKQQKILELE 1701
Cdd:PRK03918   554 L--------KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPFYNEylELKDAEKELEREEKELKKLE 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1702 EENDRLRAEVHPAGGTAKECMETLLSSNAS--------MKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES 1773
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKELEELEKKyseeeyeeLREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEE 705

                          490
                   ....*....|...
gi 1622909118 1774 NVSKQANLEATEK 1786
Cdd:PRK03918   706 REKAKKELEKLEK 718
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 951-1767 1.72e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.39  E-value: 1.72e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  951 EAKKEQVEEDNEVVsglKQNYDEMSpaglISKEELQHEFDLLKKENEQRKRKLqaALINRKELLQRVSRLEEELANLKDQ 1030
Cdd:TIGR02169  169 DRKKEKALEELEEV---EENIERLD----LIIDEKRQQLERLRREREKAERYQ--ALLKEKREYEGYELLKEKEALERQK 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1031 SKKEIPLSESERgEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQ 1110
Cdd:TIGR02169  240 EAIERQLASLEE-ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1111 DKTNQIDLLQAEISENQVIIQklttsntdasdgdsvalvketvvisppgtdsgehwkpELEEKILALEKEKEQLQKKLQE 1190
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-------------------------------------ELEREIEEERKRRDKLTEEYAE 361

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1191 ALTSRKAILKKAQEKE---RHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREsIDGKLPSPDQQewcsp 1267
Cdd:TIGR02169  362 LKEELEDLRAELEEVDkefAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD-LNAAIAGIEAK----- 435

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1268 TPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQggTSVAQIKAQLKEIETEKEKLE--LKISSTTSELTKKSE 1345
Cdd:TIGR02169  436 INELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK--EEYDRVEKELSKLQRELAEAEaqARASEERVRGGRAVE 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1346 EVF------------QLQDQINKQGLEIES-----LKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKL 1408
Cdd:TIGR02169  514 EVLkasiqgvhgtvaQLGSVGERYATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSIL 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1409 ISEKEEDVSY----------------------------------------LSGQLREKEAALTKIQTEIIEQEDLIKALH 1448
Cdd:TIGR02169  594 SEDGVIGFAVdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtLEGELFEKSGAMTGGSRAPRGGILFSRSEP 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1449 TQLEMQAkehdERIKQLQVELCEMKQKPEEIEEESRAKQQ----IQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1524
Cdd:TIGR02169  674 AELQRLR----ERLEGLKRELSSLQSELRRIENRLDELSQelsdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1525 TKSLADVESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLEN------------QSLSGSCESLKLALEGLTEDKE 1592
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelskleeevSRIEARLREIEQKLNRLTLEKE 829

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1593 KLVKEIESLKSSKIaessEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL 1672
Cdd:TIGR02169  830 YLEKEIQELQEQRI----DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKI 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1673 QEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTA------------KECMETLLSSNASMKEEVERVK 1740
Cdd:TIGR02169  906 EELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELsledvqaelqrvEEEIRALEPVNMLAIQEYEEVL 985

                          890       900
                   ....*....|....*....|....*..
gi 1622909118 1741 MEYETLSKKFQSLMSEKDSLSEEVQDL 1767
Cdd:TIGR02169  986 KRLDELKEKRAKLEEERKAILERIEEY 1012
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1395-1611 2.08e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 2.08e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:COG4942     22 AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALI----SRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1550
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLlspeDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLA 181

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1551 LLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSE 1611
Cdd:COG4942    182 ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1441-2186 2.33e-07

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 57.05  E-value: 2.33e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1441 EDLIKALHTQLEMQAKEH---DERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1517
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKfylRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1518 RDT-IEHLTKSLADVESHVSaqnkekdRVLGRLALLQEERDKLITEMDR-SLLENQSLSGSCESLKLALEgltedkeklv 1595
Cdd:pfam15921  168 SNTqIEQLRKMMLSHEGVLQ-------EIRSILVDFEEASGKKIYEHDSmSTMHFRSLGSAISKILRELD---------- 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1596 KEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEnvsneaERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQea 1675
Cdd:pfam15921  231 TEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQ------DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLE-- 302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1676 ekemeEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLms 1755
Cdd:pfam15921  303 -----IIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNL-- 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1756 eKDSLSEEVQDL-KHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVS 1834
Cdd:pfam15921  376 -DDQLQKLLADLhKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1835 EDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKM----NLLNQQIQ 1910
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLrsrvDLKLQELQ 534

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1911 EELSRVTKLKETAEE---------EKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQ 1981
Cdd:pfam15921  535 HLKNEGDHLRNVQTEcealklqmaEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKD 614

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1982 QLVKEKTKVESEIRKEYLEKIQ----GAQKEPGNKSHAKELQELLKE---KQQEVKQLQKDC----IRYQEKISALERTV 2050
Cdd:pfam15921  615 KKDAKIRELEARVSDLELEKVKlvnaGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTT 694

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2051 KALEFVQTESQKDLEITKENL-------AQAVEHRKKAQAELASFKVLLDDTQSEaarvladnLKLKKELQSNKESVKSQ 2123
Cdd:pfam15921  695 NKLKMQLKSAQSELEQTRNTLksmegsdGHAMKVAMGMQKQITAKRGQIDALQSK--------IQFLEEAMTNANKEKHF 766

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 2124 MKQKDEDLERRLEQAEekhlKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQE 2186
Cdd:pfam15921  767 LKEEKNKLSQELSTVA----TEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQD 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1305-1551 2.76e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.93  E-value: 2.76e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1305 ALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES 1384
Cdd:COG4942      8 ALLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1385 SQLQIAglehlrELQPELDELQKLISE------KEEDVSYLSGQLREKEAA--------LTKIQTEIIEQEDLIKALHTQ 1450
Cdd:COG4942     88 LEKEIA------ELRAELEAQKEELAEllralyRLGRQPPLALLLSPEDFLdavrrlqyLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1451 LEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELslaRDTIEHLTKSLAD 1530
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL---EALIARLEAEAAA 238

                          250       260
                   ....*....|....*....|.
gi 1622909118 1531 VESHVSAQNKEKDRvlGRLAL 1551
Cdd:COG4942    239 AAERTPAAGFAALK--GKLPW 257
PTZ00121 PTZ00121
MAEBL; Provisional
 1313-1877 3.37e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 3.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1313 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTAshEAEVRAESLQQKLESSQLQIAGL 1392
Cdd:PTZ00121  1320 AKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE--EAKKKADAAKKKAEEKKKADEAK 1397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1393 EHLRELQPELDELQKLISEKE--EDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQvelc 1470
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD---- 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1471 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQ----EELSLARDTIEHLTKSLADvESHVSAQNKEKDRVL 1546
Cdd:PTZ00121  1474 EAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEakkaEEAKKADEAKKAEEAKKAD-EAKKAEEKKKADELK 1552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1547 GRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEIL 1626
Cdd:PTZ00121  1553 KAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1627 LQSYENVSNEAERIQHvVEAVRQEKQElyGKLRSTEANKKETE-----KQLQEAEKEMEEMKEKMRKFA--KSKQQKILE 1699
Cdd:PTZ00121  1633 KKVEQLKKKEAEEKKK-AEELKKAEEE--NKIKAAEEAKKAEEdkkkaEEAKKAEEDEKKAAEALKKEAeeAKKAEELKK 1709

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1700 LEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEyETLSKKFQSLMSEKDSLSEEVQDLKHQL------ES 1773
Cdd:PTZ00121  1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKD-EEEKKKIAHLKKEEEKKAEEIRKEKEAVieeeldEE 1788

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1774 NVSKQANLEATEK--HDNQMNVTEEATQSIP-----GETEDQDS--LSMSTRPACSESVPSENSANPAVSEDVSSHDEIN 1844
Cdd:PTZ00121  1789 DEKRRMEVDKKIKdiFDNFANIIEGGKEGNLvindsKEMEDSAIkeVADSKNMQLEEADAFEKHKFNKNNENGEDGNKEA 1868

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1622909118 1845 NYLQQIDQLKERIAGLEEEKQKNKEFSQTLENE 1877
Cdd:PTZ00121  1869 DFNKEKDLKEDDEEEIEEADEIEKIDKDDIERE 1901
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1588-2165 4.16e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 4.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1588 TEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIqhvvEAVRQEKQELYGKLRSTEANKKE 1667
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEI----EELEKELESLEGSKRKLEEKIRE 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1668 TEKQLQEAEKEMEEMKEKMR----------------KFAKSKQQKILELEEENDRLRAEVhpaggtakECMETLLSSNAS 1731
Cdd:PRK03918   264 LEERIEELKKEIEELEEKVKelkelkekaeeyiklsEFYEEYLDELREIEKRLSRLEEEI--------NGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1732 MKEEVERVKMEYETLSKKFQSLmSEKDSLSEEVQDLKHQLESNVSKQANL---EATEKHDNQMNVTEEATQSIPGETEDQ 1808
Cdd:PRK03918   336 KEERLEELKKKLKELEKRLEEL-EERHELYEEAKAKKEELERLKKRLTGLtpeKLEKELEELEKAKEEIEEEISKITARI 414

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1809 DSLS--MSTRPACSESVPSENSANPAVSEDVSSHDE---INNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLS 1883
Cdd:PRK03918   415 GELKkeIKELKKAIEELKKAKGKCPVCGRELTEEHRkelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESE 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1884 QISTKD--GELKLLQEEVSKMNLlnqqiqEELSRVTKLKETAEEEKDDLEERLMNQLAELNgsignycqdvtdaqiKNEL 1961
Cdd:PRK03918   495 LIKLKElaEQLKELEEKLKKYNL------EELEKKAEEYEKLKEKLIKLKGEIKSLKKELE---------------KLEE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1962 LESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIqgaqkepgnkshaKELQELLKEkQQEVKQLQKDCIRYQE 2041
Cdd:PRK03918   554 LKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL-------------KELEPFYNE-YLELKDAEKELEREEK 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2042 KISALERTVKALEFVQTESQKDLEITKENLAQAveHRKKAQAELASFKVLLDDTQSEAARVLADnlklKKELQSNKESVK 2121
Cdd:PRK03918   620 ELKKLEEELDKAFEELAETEKRLEELRKELEEL--EKKYSEEEYEELREEYLELSRELAGLRAE----LEELEKRREEIK 693

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*.
gi 1622909118 2122 SQMKQKDEDLERRLEQAEEKHLKEK--KNMQEKLDALRREKVHLEE 2165
Cdd:PRK03918   694 KTLEKLKEELEEREKAKKELEKLEKalERVEELREKVKKYKALLKE 739
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 554-1433 4.91e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.83  E-value: 4.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  554 DVLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQgkrAEEGDHEVLdQKEMKQMEgegiapikmevfledtgqnfplm 633
Cdd:TIGR02168  228 ALLVLRLEELREELEELQEELKEAEEELEELTAELQ---ELEEKLEEL-RLEVSELE----------------------- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  634 pneesslpavEKEQASTEHQNRTSEEISlndagvELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQE 713
Cdd:TIGR02168  281 ----------EEIEELQKELYALANEIS------RLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  714 IYE---KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VTELRAQVRQLEmnlaeaERQRR 789
Cdd:TIGR02168  345 KLEelkEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNeIERLEARLERLE------DRRER 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  790 FDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKV 869
Cdd:TIGR02168  419 LQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  870 EELSQAlsQKELEIAKMDQLLLEKKRDVetLQQTIEEkdqqvteisfsmtekmvqlnEEKFSLGVEIkTLKEQLN-LLSR 948
Cdd:TIGR02168  499 ENLEGF--SEGVKALLKNQSGLSGILGV--LSELISV--------------------DEGYEAAIEA-ALGGRLQaVVVE 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  949 AEEAKKEQVEEDNEVVSG------LKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINrkeLLQRVsRLEE 1022
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSY---LLGGV-LVVD 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1023 ELANLKDQSKKEIPLSE---------SERGEVEEDKENKEYSekcVTSKCQEIEIsLKQTISEKEVELEHIRKDLEEKMA 1093
Cdd:TIGR02168  630 DLDNALELAKKLRPGYRivtldgdlvRPGGVITGGSAKTNSS---ILERRREIEE-LEEKIEELEEKIAELEKALAELRK 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1094 AEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVisppgtdsgEHWKPELEEK 1173
Cdd:TIGR02168  706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL---------EERLEEAEEE 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1174 ILALEKEKEQLQ---KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1250
Cdd:TIGR02168  777 LAEAEAEIEELEaqiEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1251 SIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshsedASALQGGTSVAQIKAQLKEIETEKEKLE 1330
Cdd:TIGR02168  857 LA--------------------------------------------------AEIEELEELIEELESELEALLNERASLE 886

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1331 LKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGlehlrELQPELDELQKLIS 1410
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE-----EYSLTLEEAEALEN 961

                          890       900
                   ....*....|....*....|...
gi 1622909118 1411 EKEEDVSYLSGQLREKEAALTKI 1433
Cdd:TIGR02168  962 KIEDDEEEARRRLKRLENKIKEL 984
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1360-1811 5.01e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.82  E-value: 5.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1360 EIESLKTASHEAEVRAESLQQKLESSQLQiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI-- 1437
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHEER---REELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERdd 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1438 -IEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ--------------KPEEIEEESRAKQQIQRKLQAALISRKE 1502
Cdd:PRK02224   298 lLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVaaqahneeaeslreDADDLEERAEELREEAAELESELEEARE 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1503 ALKENKS----LQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRL----ALLQEERDKLitEMDRSLLE----- 1569
Cdd:PRK02224   378 AVEDRREeieeLEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREaeleATLRTARERV--EEAEALLEagkcp 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1570 --NQSLSGSceSLKLALEGLTEDKEKLVKEIESLKS--SKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVE 1645
Cdd:PRK02224   456 ecGQPVEGS--PHVETIEEDRERVEELEAELEDLEEevEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1646 AVRQEKQELYGKLRSTEANKKETEKQLQEAekemEEMKEKMRKFAKSKQQKILELEEENDRLRAevhpaggtakecMETL 1725
Cdd:PRK02224   534 EKRERAEELRERAAELEAEAEEKREAAAEA----EEEAEEAREEVAELNSKLAELKERIESLER------------IRTL 597

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1726 LSSNASMKEEVERVKMEYETLSKKFQslmSEKDSLSEEvQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGET 1805
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELND---ERRERLAEK-RERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELR 673


                   ....*.
gi 1622909118 1806 EDQDSL 1811
Cdd:PRK02224   674 EERDDL 679
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1172-1878 5.07e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.84  E-value: 5.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1172 EKILALEKEKEQ-----LQKKLQEALTSRKAILKKAQEKERHLREelkqqkddynrLQEQFDEQSKENENIGDQLRQLQI 1246
Cdd:TIGR02169  211 ERYQALLKEKREyegyeLLKEKEALERQKEAIERQLASLEEELEK-----------LTEEISELEKRLEEIEQLLEELNK 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1247 QVRESIDGklpspdqqEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpshsEDASAlqggtSVAQIKAQLKEIETEK 1326
Cdd:TIGR02169  280 KIKDLGEE--------EQLRVKEKIGELEAEIASLERSIAEKEREL--------EDAEE-----RLAKLEAEIDKLLAEI 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1327 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQlqiaglEHLRELQPELDELQ 1406
Cdd:TIGR02169  339 EELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLK------REINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1407 KLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmQAKEHDERIKQlqvELCEMKQKPEEIEEESRAK 1486
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE-QLAADLSKYEQ---ELYDLKEEYDRVEKELSKL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1487 QQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH------------------------VSAQNKEK 1542
Cdd:TIGR02169  489 QRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERyataievaagnrlnnvvveddavaKEAIELLK 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 DRVLGRLALL------QEERDKLITEMD---------------------------------------------------- 1564
Cdd:TIGR02169  569 RRKAGRATFLplnkmrDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlvvedieaarrlmgkyrmvtlegel 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1565 --------------RSLLENQ-SLSGSCESLKLALEGLTEDKEKLVKE---IESLKSSKIAESSEWQEKHKELQKEYEIL 1626
Cdd:TIGR02169  649 feksgamtggsrapRGGILFSrSEPAELQRLRERLEGLKRELSSLQSElrrIENRLDELSQELSDASRKIGEIEKEIEQL 728

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1627 LQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQL-QEAEKEMEEMKEKMRKFAKSKQQKILELEEEND 1705
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLhKLEEALNDLEARLSHSRIPEIQAELSKLEEEVS 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1706 RLRA----------EVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQS--------------LMSEKDSLS 1761
Cdd:TIGR02169  809 RIEArlreieqklnRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEleeeleeleaalrdLESRLGDLK 888

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1762 EEVQDLKHQLESNVSKQANLEAT----EKHDNQMNVTEEATQSIPGETEDQDSlSMSTRPACSESVPSENSANPAVSEDV 1837
Cdd:TIGR02169  889 KERDELEAQLRELERKIEELEAQiekkRKRLSELKAKLEALEEELSEIEDPKG-EDEEIPEEELSLEDVQAELQRVEEEI 967

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 1622909118 1838 SSHDEINN--------YLQQIDQLKERIAGLEEEKQKNKEFSQTLENER 1878
Cdd:TIGR02169  968 RALEPVNMlaiqeyeeVLKRLDELKEKRAKLEEERKAILERIEEYEKKK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1076-1675 5.13e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 55.71  E-value: 5.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1076 EKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvi 1155
Cdd:COG1196    222 LKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA--- 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1156 sppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAIlkkaQEKERHLREELKQQKDDYNRLQEQFDEQSKENE 1235
Cdd:COG1196    299 -------------RLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEELEEAEAELA 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1236 NIGDQLRQLQIQVREsidgklpspDQQEWcsptpgleeplfkateqhhtqpvlesnlcpdwpsHSEDASALQGGTSVAQI 1315
Cdd:COG1196    362 EAEEALLEAEAELAE---------AEEEL----------------------------------EELAEELLEALRAAAEL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1316 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLE-H 1394
Cdd:COG1196    399 AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEaA 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdLIKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:COG1196    479 LAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA-VAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRV-------LG 1547
Cdd:COG1196    558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVaarleaaLR 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1548 RLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILL 1627
Cdd:COG1196    638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1622909118 1628 QSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1675
Cdd:COG1196    718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEEL 765
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1891-2744 5.52e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.75  E-value: 5.52e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1891 ELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELN---GSIGNYCQDVTDAQIKNELLESEMK 1967
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYllyLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1968 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2047
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2048 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2127
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLEL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2128 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTvaqlaaftkSMSSLQD 2207
Cdd:pfam02463  414 ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKET---------QLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2208 DRDRVIDEAKKWERKFSdaiQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVC 2287
Cdd:pfam02463  485 QLELLLSRQKLEERSQK---ESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVE 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2288 DTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQL 2367
Cdd:pfam02463  562 ERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESA 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2368 ETDLQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTN 2447
Cdd:pfam02463  642 KAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEE 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2448 QLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIvGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHM 2527
Cdd:pfam02463  722 LLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLK-KEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2528 DDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD 2607
Cdd:pfam02463  801 EELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2608 LSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDK 2687
Cdd:pfam02463  881 EQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEE 960

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2688 LKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSF 2744
Cdd:pfam02463  961 RNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1436-2034 6.03e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 55.46  E-value: 6.03e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1436 EIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELS 1515
Cdd:PRK03918   183 KFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIR 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1516 LARDTIEHLTKSLADVEshvsaqnkEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLtedkEKLV 1595
Cdd:PRK03918   263 ELEERIEELKKEIEELE--------EKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI----EERI 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1596 KEIESLKSskiaESSEWQEKHKELQKEYEILLQSYEnvsnEAERIQHVVEAVRQEKQELYGKlrsteaNKKETEKQLQEA 1675
Cdd:PRK03918   331 KELEEKEE----RLEELKKKLKELEKRLEELEERHE----LYEEAKAKKEELERLKKRLTGL------TPEKLEKELEEL 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1676 EKEMEEMKEKMRKFakskQQKILELEEENDRLRAEVHPAGGTAKECMetlLSSNASMKEEVERVKMEYETLSKKFQSLMS 1755
Cdd:PRK03918   397 EKAKEEIEEEISKI----TARIGELKKEIKELKKAIEELKKAKGKCP---VCGRELTEEHRKELLEEYTAELKRIEKELK 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1756 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSanpAVSE 1835
Cdd:PRK03918   470 EIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIK---SLKK 546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1836 DVSSHDEINNYLQqidQLKERIAGLEEEKqknKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSR 1915
Cdd:PRK03918   547 ELEKLEELKKKLA---ELEKKLDELEEEL---AELLKELEELGFESVEELEERLKELEPFYNEYLELKDAEKELEREEKE 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1916 VTKLKETAEEEKDDLEErLMNQLAELNGSIGNYCQDVTDAQIKNelLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1995
Cdd:PRK03918   621 LKKLEEELDKAFEELAE-TEKRLEELRKELEELEKKYSEEEYEE--LREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1622909118 1996 --KEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2034
Cdd:PRK03918   698 klKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLK 738
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1387-1662 6.48e-07

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 55.32  E-value: 6.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1387 LQIAGLEhlRELQPELDELQKL----ISEKEEDVSYLsgQLREKEAALTKIQTEIIEQEDLIKALHT----QLEMQAKEH 1458
Cdd:PRK05771     9 VLIVTLK--SYKDEVLEALHELgvvhIEDLKEELSNE--RLRKLRSLLTKLSEALDKLRSYLPKLNPlreeKKKVSVKSL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1459 DERIKQLQVELcemkqkpEEIEEESRAKQQIQRKLQA---ALISRKEALKENKSLQEELSLARDT-----------IEHL 1524
Cdd:PRK05771    85 EELIKDVEEEL-------EKIEKEIKELEEEISELENeikELEQEIERLEPWGNFDLDLSLLLGFkyvsvfvgtvpEDKL 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1525 TKSLADVESHVS---AQNKEKDRVLgrLALLQEERDKLITEMDRSLLENQSLSGScESLKLALEGLTEDKEKLVKEIESL 1601
Cdd:PRK05771   158 EELKLESDVENVeyiSTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESL 234

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1602 KsSKIAESSEwqekhkelqKEYEILLQSYENVSNEAERiqhvveavrqekQELYGKLRSTE 1662
Cdd:PRK05771   235 L-EELKELAK---------KYLEELLALYEYLEIELER------------AEALSKFLKTD 273
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 927-1588 7.41e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.36  E-value: 7.41e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  927 EEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEfDLLKKENEQRKRKLQAA 1006
Cdd:TIGR00618  187 AKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQK-REAQEEQLKKQQLLKQL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1007 LINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRK 1086
Cdd:TIGR00618  266 RARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRR 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1087 DLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHW 1166
Cdd:TIGR00618  346 LLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQ 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1167 KPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDdynrlQEQFDEQSKENENIGDQLRQLQI 1246
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVLARLLELQ 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1247 QVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHHTQPVLESNlcpdwpshSEDASALQGGTSVAQIKAQLKEIETEK 1326
Cdd:TIGR00618  501 EEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEE--------DVYHQLTSERKQRASLKEQMQEIQQSF 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1327 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAE----------SLQQKLESSQLQIAGLEHLR 1396
Cdd:TIGR00618  573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdvrlHLQQCSQELALKLTALHALQ 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1397 ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDL--IKALHTQLEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:TIGR00618  653 LTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLaqCQTLLRELETHIEEYDREFNEIENASSSLGS 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 kpeEIEEESRAKQQIQRKLQAaliSRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1554
Cdd:TIGR00618  733 ---DLAAREDALNQSLKELMH---QARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEA 806

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1622909118 1555 E-RDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1588
Cdd:TIGR00618  807 EiGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841
PTZ00121 PTZ00121
MAEBL; Provisional
 710-1237 7.55e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.53  E-value: 7.55e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  710 KAQEIYEKNLDEKAKEISNLNQLIE--EFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQ 787
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  788 RRFDYESQTAHHNLLTEQIHSLSIEAKSKD---VKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVL----EGAE 860
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAkkkaEEAK 1444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  861 RVRHISSKVEELSQA--LSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlNEEKFSLGVEI 936
Cdd:PTZ00121  1445 KADEAKKKAEEAKKAeeAKKKAEEAKKADEAKkkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK---KADEAKKAEEA 1521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  937 KTLKEqlnlLSRAEEAKKEQVEEDNEVvsglKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQR 1016
Cdd:PTZ00121  1522 KKADE----AKKAEEAKKADEAKKAEE----KKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEAR 1593

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1017 VSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE 1096
Cdd:PTZ00121  1594 IEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED 1673

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1097 QLQAlvKEMNQTLQDKTNQIDLLQAEISENQviiqklttsntdasdgdsvalvketvvisppgtdsgehwKPELEEKILA 1176
Cdd:PTZ00121  1674 KKKA--EEAKKAEEDEKKAAEALKKEAEEAK---------------------------------------KAEELKKKEA 1712

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1177 LEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:PTZ00121  1713 EEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEI 1773
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2592-2796 1.04e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 54.92  E-value: 1.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2592 EDLQRSSNALQ--EEKRDLSKEIESLKVSVSQLTRQVTALQEEG-TLGIYHAQLKVK---------EEELQRLSALLSSS 2659
Cdd:COG4913    235 DDLERAHEALEdaREQIELLEPIRELAERYAAARERLAELEYLRaALRLWFAQRRLElleaeleelRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2660 QKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLmvtKENKDLTA 2739
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFA---ALRAEAAA 391

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2740 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2796
Cdd:COG4913    392 LLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 284-888 1.29e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.29e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  284 DLLQQELTAAEQRNQILSQQLQQIEAEHNtlrntvETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAG-- 361
Cdd:COG1196    223 KELEAELLLLKLRELEAELEELEAELEEL------EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLae 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  362 QAQAELESRYSALEQKH-KAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSK 440
Cdd:COG1196    297 LARLEQDIARLEERRRElEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  441 EISQFLNRlpLQQHETASQtcfpdvynegTQAVTEENIASLQKRVVELENEKGALL--LSSIELEELKAENEKLSSQITL 518
Cdd:COG1196    377 AEEELEEL--AEELLEALR----------AAAELAAQLEELEEAEEALLERLERLEeeLEELEEALAELEEEEEEEEEAL 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  519 LEAQNRIGEADREVSEISIVDDANKRSSSTEESGQDVLENTFSQKHKELSVLLLEMKEAQEEI----AFLKLQLQGKRAE 594
Cdd:COG1196    445 EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLegvkAALLLAGLRGLAG 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  595 EGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQ 674
Cdd:COG1196    525 AVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  675 DCDKSLSAVPDIGQcHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNAdNNSSAFTALSEER 754
Cdd:COG1196    605 ASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE-LLAALLEAEAELE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  755 DQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQF 834
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909118  835 SEQSTLIRSLQSQLQN---------KESEVLEgaERVRHISSKVEELSQALSQKELEIAKMDQ 888
Cdd:COG1196    763 EELERELERLEREIEAlgpvnllaiEEYEELE--ERYDFLSEQREDLEEARETLEEAIEEIDR 823
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1313-2550 1.40e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 54.67  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1313 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQIN---KQGLEIES----LKTASHEAEVRAESLQQKLESS 1385
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELEEENEDSIHLEKEIKdlfDKYLEIDDeiiyINKLKLELKEKIKNISDKNEYI 619

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1386 QLQIAGLEHLRELQPELDELQKLISEKeedvsyLSGQLREKEAALTKIQTEIIE-QEDLIKALHTQLEMQAKEHDERIKQ 1464
Cdd:TIGR01612  620 KKAIDLKKIIENNNAYIDELAKISPYQ------VPEHLKNKDKIYSTIKSELSKiYEDDIDALYNELSSIVKENAIDNTE 693

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1465 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKE------ALKENKSLQEELSLARD-TIEHLTKSLADVESHVSA 1537
Cdd:TIGR01612  694 DKAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKnelldiIVEIKKHIHGEINKDLNkILEDFKNKEKELSNKIND 773

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1538 QNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKS------SKIAESSE 1611
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFmkddflNKVDKFIN 853

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1612 WQEKHKE-LQKEYEILLQSYENVSNEaeriqhvveaVRQEKQELY-GKLRSTEANKKETEKQLQEAEKEMEEMKEKMR-- 1687
Cdd:TIGR01612  854 FENNCKEkIDSEHEQFAELTNKIKAE----------ISDDKLNDYeKKFNDSKSLINEINKSIEEEYQNINTLKKVDEyi 923

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1688 KFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMetllSSNASMKEEVERVKMEYET-LSKKFQSL-MSEKDSLSEEVQ 1765
Cdd:TIGR01612  924 KICENTKESIEKFHNKQNILKEILNKNIDTIKESN----LIEKSYKDKFDNTLIDKINeLDKAFKDAsLNDYEAKNNELI 999

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1766 DLKHQLESNVSKqaNLEATEKHdnQMNVTEEATQSIPGETEDqdslsmstrpacsesvpsensANPAVSE-DVSSHDEIN 1844
Cdd:TIGR01612 1000 KYFNDLKANLGK--NKENMLYH--QFDEKEKATNDIEQKIED---------------------ANKNIPNiEIAIHTSIY 1054

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1845 NYLQQIDQL-KERIAGLEEEKQKNKEFSQTLENERNALLSQIS----TKDGELKlLQEEVSK----MNLLNQQIQEELSR 1915
Cdd:TIGR01612 1055 NIIDEIEKEiGKNIELLNKEILEEAEINITNFNEIKEKLKHYNfddfGKEENIK-YADEINKikddIKNLDQKIDHHIKA 1133

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1916 VTKLKETAEEEKDDLEERLmnqlaelngsigNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEK------QQLVKEKTK 1989
Cdd:TIGR01612 1134 LEEIKKKSENYIDEIKAQI------------NDLEDVADKAISNDDPEEIEKKIENIVTKIDKKKniydeiKKLLNEIAE 1201

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1990 VESEirKEYLEKIQGAqkepgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEK-ISALERTVKALEFVQTESQKDLEITK 2068
Cdd:TIGR01612 1202 IEKD--KTSLEEVKGI-----NLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAyIEDLDEIKEKSPEIENEMGIEMDIKA 1274

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2069 ENLAQAVEHRKKAQAELASFK--VLLDDTQSEAARVLADNLK------LKKELQSNkesvKSQMKQKDEDLERRLEQ-AE 2139
Cdd:TIGR01612 1275 EMETFNISHDDDKDHHIISKKhdENISDIREKSLKIIEDFSEesdindIKKELQKN----LLDAQKHNSDINLYLNEiAN 1350

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2140 EKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDstvaqLAAFTKSMSSLQDDRDrvIDEAKKW 2219
Cdd:TIGR01612 1351 IYNILKLNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDIN-----LEECKSKIESTLDDKD--IDECIKK 1423

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2220 ERKFSDAIQTKEEEI-----RLKEENCSVLK-----DQLRQMSIHMEELKINISRLEHDKQIWESKAQTEvqlQQKVCDT 2289
Cdd:TIGR01612 1424 IKELKNHILSEESNIdtyfkNADENNENVLLlfkniEMADNKSQHILKIKKDNATNDHDFNINELKEHID---KSKGCKD 1500

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2290 LQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEA------DIQNSKFS 2363
Cdd:TIGR01612 1501 EADKNAKAIEKNKELFEQYKKDVTELLNKYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKseqkikEIKKEKFR 1580

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2364 YEQLETDLQASRELTSRLHEEINMKEQKMISllsgkeeaiqvaIAELRQQHDKEIKELENLLSQEEEENIVLEEEN-KKA 2442
Cdd:TIGR01612 1581 IEDDAAKNDKSNKAAIDIQLSLENFENKFLK------------ISDIKKKINDCLKETESIEKKISSFSIDSQDTElKEN 1648

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2443 VDKTNQLMETLNAIK--KENIQ-QKAQLDSFVKSMSSLQNDRDRIVGDYQqleerhlSVILEKdqlIQEAAAEN-NKLKE 2518
Cdd:TIGR01612 1649 GDNLNSLQEFLESLKdqKKNIEdKKKELDELDSEIEKIEIDVDQHKKNYE-------IGIIEK---IKEIAIANkEEIES 1718

                         1290      1300      1310
                   ....*....|....*....|....*....|..
gi 1622909118 2519 EIRGLRSHMDDLNSENAKLDAELIQYREDLNQ 2550
Cdd:TIGR01612 1719 IKELIEPTIENLISSFNTNDLEGIDPNEKLEE 1750
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 997-1660 1.47e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.17  E-value: 1.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  997 EQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKeiplsesergeveedkenkeysekcvtskcqeieisLKQTISE 1076
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEE------------------------------------LEAELAE 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1077 KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvis 1156
Cdd:COG1196    265 LEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE---- 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1157 ppgtdsgehwkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENEN 1236
Cdd:COG1196    341 ------------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1237 IGDQLRQLQIQVRESIdgklpspdqqewcsptpgleeplfkateqhhtqpvlesnlcpdwpshSEDASALQGGTSVAQIK 1316
Cdd:COG1196    409 EEALLERLERLEEELE-----------------------------------------------ELEEALAELEEEEEEEE 441

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1317 AQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtASHEAEVRAESLQQKLESSQLQIAGLEHLR 1396
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAA-ARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1397 ELQPELDELQKLISEKEEDV-SYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQK 1475
Cdd:COG1196    521 GLAGAVAVLIGVEAAYEAALeAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAA 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1476 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1555
Cdd:COG1196    601 VDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAE 680

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1556 RDKLITEMDRSLLENQslsgscESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSN 1635
Cdd:COG1196    681 LEELAERLAEEELELE------EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALE 754

                          650       660
                   ....*....|....*....|....*
gi 1622909118 1636 EAERIQhVVEAVRQEKQELYGKLRS 1660
Cdd:COG1196    755 ELPEPP-DLEELERELERLEREIEA 778
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1080-1640 1.53e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 54.30  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1080 ELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsntdaSDGDSVALVKETVVISPPG 1159
Cdd:PRK03918   173 EIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLE------KEVKELEELKEEIEELEKE 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1160 TDSGEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAI--LKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENI 1237
Cdd:PRK03918   247 LESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELkeLKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGI 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1238 GDQLRQLQIQVRESidgklpspdqQEWCSPTPGLEEPLFKATEQHHTQPVLESNLcpdwpSHSEDASALQGGTSVAQIKA 1317
Cdd:PRK03918   327 EERIKELEEKEERL----------EELKKKLKELEKRLEELEERHELYEEAKAKK-----EELERLKKRLTGLTPEKLEK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1318 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINkqglEIESLK----------TASHEAEVRAESLQQKLESSQL 1387
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIE----ELKKAKgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1388 QIAGLEHLRELQPELDELQKLISEKEEDVSY--LSGQLREKEAALTKIQTEIIEQE----DLIKALHTQLEMQ---AKEH 1458
Cdd:PRK03918   468 LKEIEEKERKLRKELRELEKVLKKESELIKLkeLAEQLKELEEKLKKYNLEELEKKaeeyEKLKEKLIKLKGEiksLKKE 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1459 DERIKQLQVELCEMKQKPEEIEEE-SRAKQQIQRKLQAALISRKEALKENKSLQE---ELSLARDTIEHLTKSLADVESH 1534
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEElAELLKELEELGFESVEELEERLKELEPFYNeylELKDAEKELEREEKELKKLEEE 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1535 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSllENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSkIAESSEWQE 1614
Cdd:PRK03918   628 LDKAFEELAETEKRLEELRKELEELEKKYSEE--EYEELREEYLELSRELAGLRAELEELEKRREEIKKT-LEKLKEELE 704

                          570       580
                   ....*....|....*....|....*.
gi 1622909118 1615 KHKELQKEYEILLQSYENVSNEAERI 1640
Cdd:PRK03918   705 EREKAKKELEKLEKALERVEELREKV 730
PTZ00121 PTZ00121
MAEBL; Provisional
 1987-2693 2.36e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.99  E-value: 2.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1987 KTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKdcIRYQEKISALERTVKALEFVQTESQKDLE- 2065
Cdd:PTZ00121  1085 EDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEE--ARKAEDARKAEEARKAEDAKRVEIARKAEd 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2066 ITKENLAQAVEHRKKAQAELASFKV--------LLDDTQSEAARvLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQ 2137
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKAEAARKAEEVrkaeelrkAEDARKAEAAR-KAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEE 1241

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2138 AeeKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQD--DRDRVIDE 2215
Cdd:PTZ00121  1242 A--KKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKkaEEAKKADE 1319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2216 AKK---WERKFSDAIQTKEEEIRLKEEnCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQG 2292
Cdd:PTZ00121  1320 AKKkaeEAKKKADAAKKKAEEAKKAAE-AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2293 ENKELLSQLEETRHLYHNSQN-ELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdiqnSKFSYEQLETDL 2371
Cdd:PTZ00121  1399 KAEEDKKKADELKKAAAAKKKaDEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEA----KKKAEEAKKADE 1474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2372 QASRELTSRLHEEINMK---EQKMISLLSGKEEAIQVAiAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQ 2448
Cdd:PTZ00121  1475 AKKKAEEAKKADEAKKKaeeAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKK 1553

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2449 LMETLNAIKKENIQQKaqldsfvKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMD 2528
Cdd:PTZ00121  1554 AEELKKAEEKKKAEEA-------KKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELK 1626

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2529 DLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQlqqnkELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDL 2608
Cdd:PTZ00121  1627 KAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAA-----EEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2609 SKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKL 2688
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781


                   ....*
gi 1622909118 2689 KKELK 2693
Cdd:PTZ00121  1782 EEELD 1786
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1719-2348 2.58e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.58  E-value: 2.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1719 KECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV-----SKQANLEATEK 1786
Cdd:pfam15921   88 KDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVheleaAKCLKEDMLED 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1787 HDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQIDQ----LKERIAGLEE 1862
Cdd:pfam15921  168 SNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELDTeisyLKGRIFPVED 245

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1863 EKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkETAEEEKDDLEERLMNQ 1937
Cdd:pfam15921  246 QLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EIIQEQARNQNSMYMRQ 318

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1938 LAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKS 2013
Cdd:pfam15921  319 LSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKE 398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2014 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALefvQTESQKDLEitkeNLAQAVEHRKKAQAELASFKVLLD 2093
Cdd:pfam15921  399 QNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAM---KSECQGQME----RQMAAIQGKNESLEKVSSLTAQLE 471

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2094 DTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLE--QAEEKHLKEKKNMQ-EKLDALRREKVHLEETIGE- 2169
Cdd:pfam15921  472 STK-EMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEatNAEITKLRSRVDLKlQELQHLKNEGDHLRNVQTEc 550

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2170 --IQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVideakkwERKFSDA-IQTKEEEIRLKEENCSVLKD 2246
Cdd:pfam15921  551 eaLKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQL-------EKEINDRrLELQEFKILKDKKDAKIREL 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2247 QLRQMSIHMEELKINISRLEHDKQIWESKaqtevQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILK 2326
Cdd:pfam15921  624 EARVSDLELEKVKLVNAGSERLRAVKDIK-----QERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLK 698

                          650       660
                   ....*....|....*....|..
gi 1622909118 2327 DQLTDLSNSLEKCKEQKENLEG 2348
Cdd:pfam15921  699 MQLKSAQSELEQTRNTLKSMEG 720
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
682-1119 2.79e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 2.79e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  682 AVPDIGQCHQDELERLKSQILELE-LNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLlaq 760
Cdd:PRK02224   177 GVERVLSDQRGSLDQLKAQIEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREEL--- 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  761 vkelsvvTELRAQVRQLEMNLAEAERQRR-FDYESQTAHHNLLT--EQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQ 837
Cdd:PRK02224   254 -------ETLEAEIEDLRETIAETEREREeLAEEVRDLRERLEEleEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  838 STLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQV------ 911
Cdd:PRK02224   327 RDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvd 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  912 ----TEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKK----EQVEEDNEVVSGLKQNYDEmspaglisKE 983
Cdd:PRK02224   407 lgnaEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIEEDRER--------VE 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  984 ELQHEFDLLKKENEQRKRKLQAAlINRKELLQRVSRLEEELANLKDqskkeipLSESERGEVEEDKENKEysekcvtskc 1063
Cdd:PRK02224   479 ELEAELEDLEEEVEEVEERLERA-EDLVEAEDRIERLEERREDLEE-------LIAERRETIEEKRERAE---------- 540

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 1064 qeieiSLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLL 1119
Cdd:PRK02224   541 -----ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2246-2863 2.82e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.38  E-value: 2.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2246 DQLRQMSIHMEELKINISRLEHDKQIWES--KAQTEVQLQQKVCDTLQGENKELLSQLEETRHlyHNSQNELAKLESELN 2323
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLRAALRLWFAQRRLELLEAEL--EELRAELARLEAELE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2324 ILKDQLTDLSNSLEKCKEQKENLEGIIRQQ-EADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMisllsgkeEA 2402
Cdd:COG4913    313 RLEARLDALREELDELEAQIRGNGGDRLEQlEREIERLERELEERERRRARLEALLAALGLPLPASAEEF--------AA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2403 IQVAIAELRQQHDKEIKELENLLSQEEEENivleeenKKAVDKTNQLMETLNAIKkeniQQKAQLDSFVKSM-----SSL 2477
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAAL-------RDLRRELRELEAEIASLE----RRKSNIPARLLALrdalaEAL 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2478 QNDRD--RIVGDYQQLEERH---------------LSVILEKDQLIQEAAA-ENNKLKEEIRGLRSHMDDLNSENAKLDA 2539
Cdd:COG4913    454 GLDEAelPFVGELIEVRPEEerwrgaiervlggfaLTLLVPPEHYAAALRWvNRLHLRGRLVYERVRTGLPDPERPRLDP 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2540 EliqyreDLNQVISIKDSQQKQLLEAQLQQNKELknkyakleeklkeseeanedlqrssnalqeekrdlskeiesLKV-S 2618
Cdd:COG4913    534 D------SLAGKLDFKPHPFRAWLEAELGRRFDY-----------------------------------------VCVdS 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2619 VSQLTRQVTALQEEGTL-GIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKkVGEIEDKLKKELKHLH- 2696
Cdd:COG4913    567 PEELRRHPRAITRAGQVkGNGTRHEKDDRRRIRSRYVLGFDNRAKLAALEAELAELEEELAE-AEERLEALEAELDALQe 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2697 -HDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAqiqsfgrsmsslqnsrdhANEELDELKRKYDASLKE 2775
Cdd:COG4913    646 rREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA------------------LEEQLEELEAELEELEEE 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2776 LAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLlskDEQLLHLssQLEDSYNQV-QSFSKAMASLQNER 2854
Cdd:COG4913    708 LDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL---EERFAAA--LGDAVERELrENLEERIDALRARL 782


                   ....*....
gi 1622909118 2855 DHLWNELEK 2863
Cdd:COG4913    783 NRAEEELER 791
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1318-1468 2.97e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 2.97e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1318 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRE 1397
Cdd:COG1579     11 DLQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKE 90

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1622909118 1398 ---LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVE 1468
Cdd:COG1579     91 yeaLQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAE 164
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2313-2933 3.02e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 3.02e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2313 NELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLEtdlQASRELTSRLheeinMKEQKM 2392
Cdd:TIGR04523   26 NIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILE---QQIKDLNDKL-----KKNKDK 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2393 ISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMET---LNAIKKENIQQKAQLDS 2469
Cdd:TIGR04523   98 INKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLnnkYNDLKKQKEELENELNL 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2470 FVKSMSSLQNDRDRIVGDYQQLEERhLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLN 2549
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2550 QVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKE-SEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQ 2625
Cdd:TIGR04523  257 QLKDEQNKIKKQLSEKQKeleQNNKKIKELEKQLNQLKSEiSDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKI 336

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2626 VTALQEegtlgiyhaQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED------KLKKELKHLHHDA 2699
Cdd:TIGR04523  337 ISQLNE---------QISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesqinDLESKIQNQEKLN 407

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2700 GIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQL 2779
Cdd:TIGR04523  408 QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQK 487

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2780 KEQQGLLNRERHALLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQS------FSKAMASLQNE 2853
Cdd:TIGR04523  488 QKELKSKEKELKKLNEEKKEL-----EEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDelnkddFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2854 RDHLWNELEKFR---KSEEGKQRSAAQPATSL-AEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQ 2929
Cdd:TIGR04523  563 IDEKNKEIEELKqtqKSLKKKQEEKQELIDQKeKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNK 642


                   ....
gi 1622909118 2930 LQEY 2933
Cdd:TIGR04523  643 LKQE 646
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2497-2913 3.05e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.53  E-value: 3.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2497 SVILEKD--QLIQEAAAENNKLKEEIRGLrshmDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLleAQLQQNKELK 2574
Cdd:TIGR02169  137 NVVLQGDvtDFISMSPVERRKIIDEIAGV----AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQL--ERLRREREKA 210

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2575 NKYakleeklkeseeanedlqrssNALQEEKRD-----LSKEIESLKVSVSQLTRQVTALqeegtlgiyhaqlkvkEEEL 2649
Cdd:TIGR02169  211 ERY---------------------QALLKEKREyegyeLLKEKEALERQKEAIERQLASL----------------EEEL 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2650 QRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLHhdagimrNETETAEERVAELARDLVEMEQKLLM 2729
Cdd:TIGR02169  254 EKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELE-------AEIASLERSIAEKERELEDAEERLAK 326

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2730 VTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTfsmDLPEEnsl 2809
Cdd:TIGR02169  327 LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE---KLKRE--- 400

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2810 syLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKfrksEEGKQRSAAqpatslAEVQSLK 2889
Cdd:TIGR02169  401 --INELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK----QEWKLEQLA------ADLSKYE 468

                          410       420
                   ....*....|....*....|....
gi 1622909118 2890 KAMSSLQNDRDRLLKELKNLQQQY 2913
Cdd:TIGR02169  469 QELYDLKEEYDRVEKELSKLQREL 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2600-3198 3.35e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 3.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2600 ALQEEKRDLSK-----EIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQ 2674
Cdd:TIGR02168  217 ELKAELRELELallvlRLEELREELEELQEELKEAEEE--LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALA 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2675 KEAAKKVGEIEdKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNS 2754
Cdd:TIGR02168  295 NEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2755 RDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSEttfsmdlpeenslsyLEKLNQQLLSKDEQLLhlSSQLE 2834
Cdd:TIGR02168  374 LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDR---------------RERLQQEIEELLKKLE--EAELK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2835 DSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYL 2914
Cdd:TIGR02168  437 ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQS 516

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2915 QINQ------EITELRP---------LKAQLQEYQDKTKTFQIM-QEELRQENLSWQH--ELHQLRMEKSSWEIHERRMK 2976
Cdd:TIGR02168  517 GLSGilgvlsELISVDEgyeaaieaaLGGRLQAVVVENLNAAKKaIAFLKQNELGRVTflPLDSIKGTEIQGNDREILKN 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2977 -EQYLMAISDKDQQVSHLQNLIRELRSSSS------QAQPLKVQYQRQASPET----SASPDGSQN----------LIYE 3035
Cdd:TIGR02168  597 iEGFLGVAKDLVKFDPKLRKALSYLLGGVLvvddldNALELAKKLRPGYRIVTldgdLVRPGGVITggsaktnssiLERR 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3036 TEL--LRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQAVS 3113
Cdd:TIGR02168  677 REIeeLEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3114 KEKgpLNIDVAPGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLCNTRQEVNELRKLLEEERD----------------- 3176
Cdd:TIGR02168  757 TEL--EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlrerleslerria 834

                          650       660
                   ....*....|....*....|....*.
gi 1622909118 3177 ----QRVAAENALSLAEEQIRRLEHS 3198
Cdd:TIGR02168  835 aterRLEDLEEQIEELSEDIESLAAE 860
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 479-1253 3.47e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 53.14  E-value: 3.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  479 ASLQKRVVELENEKGAL--LLSSIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIvDDANKRSSSTEESgQDVL 556
Cdd:TIGR02168  209 AEKAERYKELKAELRELelALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKL-EELRLEVSELEEE-IEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  557 ENTFSQKHKELSVLLLEMKEAQEEIAFLK---LQLQGKRAEEGDHEVLDQKEMKQMEGEgiapikmevfLEDTGQNFPLM 633
Cdd:TIGR02168  287 QKELYALANEISRLEQQKQILRERLANLErqlEELEAQLEELESKLDELAEELAELEEK----------LEELKEELESL 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  634 PNEESSLPAVEKEQASTEHQNRTsEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQ- 712
Cdd:TIGR02168  357 EAELEELEAELEELESRLEELEE-QLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAEl 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  713 EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDY 792
Cdd:TIGR02168  436 KELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  793 ESQTAHHNLLTEQIH-----SLSIEA----KSKDVKIEVLQNELDDVQLQfsEQSTLIRSL--------QSQLQNKESEV 855
Cdd:TIGR02168  516 SGLSGILGVLSELISvdegyEAAIEAalggRLQAVVVENLNAAKKAIAFL--KQNELGRVTflpldsikGTEIQGNDREI 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  856 LEGAERVRHISSKVEELSQALSqkeleiaKMDQLLLEKKRDVETLQQTIEE------------KDQQVTEISFSMTEKMV 923
Cdd:TIGR02168  594 LKNIEGFLGVAKDLVKFDPKLR-------KALSYLLGGVLVVDDLDNALELakklrpgyrivtLDGDLVRPGGVITGGSA 666

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  924 QLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEdnevVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKL 1003
Cdd:TIGR02168  667 KTNSSILERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1004 QAalinrkeLLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEH 1083
Cdd:TIGR02168  743 EQ-------LEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK-ALREALDELRAELTL 814

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1084 IRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISppGTDSG 1163
Cdd:TIGR02168  815 LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEE--ALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1164 EHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQ 1243
Cdd:TIGR02168  893 RSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARR 972

                          810
                   ....*....|
gi 1622909118 1244 LQIQVRESID 1253
Cdd:TIGR02168  973 RLKRLENKIK 982
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2134-2777 3.59e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 3.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2134 RLEQAEEKHLKEKKNMQEKLDALRRE---KVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRD 2210
Cdd:PRK03918   159 DYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKE 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2211 RvIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkdQLRQMSIHMEELKINISRLEHDKQIWEskaqtevqlqqkvcdtl 2290
Cdd:PRK03918   239 E-IEELEKELESLEGSKRKLEEKIRELEE-------RIEELKKEIEELEEKVKELKELKEKAE----------------- 293

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2291 qgENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEAdIQNSKFSYEQLETD 2370
Cdd:PRK03918   294 --EYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAKAK 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2371 LQASRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQqhdkEIKELENLLSQEEEENIVLeeenKKAVDKTNQLM 2450
Cdd:PRK03918   371 KEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEEL----KKAKGKCPVCG 442

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2451 ETLNAIKKENIqqkaqLDSFVKSMSSLQNDRDRIVGDYQQLEERhlSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2530
Cdd:PRK03918   443 RELTEEHRKEL-----LEEYTAELKRIEKELKEIEEKERKLRKE--LRELEKVLKKESELIKLKELAEQLKELEEKLKKY 515

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2531 NSENAKLDAEliQYREDLNQVISIKDSQQKqlLEAQLQQNKELKNKYAKleeklkeseeanedLQRSSNALQEEKRDLSK 2610
Cdd:PRK03918   516 NLEELEKKAE--EYEKLKEKLIKLKGEIKS--LKKELEKLEELKKKLAE--------------LEKKLDELEEELAELLK 577

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2611 EIESLKV-SVSQLTRQVTALQEegtlgIYHAQLKVK--EEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED- 2686
Cdd:PRK03918   578 ELEELGFeSVEELEERLKELEP-----FYNEYLELKdaEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEEl 652

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2687 ----------KLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLlmvtKENKDLTAQIQSFGRSMSSLqnsrd 2756
Cdd:PRK03918   653 ekkyseeeyeELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEEL----EEREKAKKELEKLEKALERV----- 723

                          650       660
                   ....*....|....*....|.
gi 1622909118 2757 hanEELDELKRKYDASLKELA 2777
Cdd:PRK03918   724 ---EELREKVKKYKALLKERA 741
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1316-1782 3.83e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.72  E-value: 3.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1316 KAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHL 1395
Cdd:TIGR04523  123 EVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1396 -----------RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQ 1464
Cdd:TIGR04523  203 lsnlkkkiqknKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKK 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1465 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENksLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDR 1544
Cdd:TIGR04523  283 IKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEE--IQNQISQNNKIISQLNEQISQLKKELTNSESENSE 360

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1545 VLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLAL--------------EGLTEDKEKLVKEIESLKSSKIAESS 1610
Cdd:TIGR04523  361 KQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIqnqeklnqqkdeqiKKLQQEKELLEKEIERLKETIIKNNS 440

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1611 EWQE----------KHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEME 1680
Cdd:TIGR04523  441 EIKDltnqdsvkelIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKIS 520

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1681 EMKEKMRKFAKSKQQKILELEEENDRLRAEvhpAGGTAKECMETLLSSNasmKEEVERVKMEYETLSKKFQSLMSEKDSL 1760
Cdd:TIGR04523  521 SLKEKIEKLESEKKEKESKISDLEDELNKD---DFELKKENLEKEIDEK---NKEIEELKQTQKSLKKKQEEKQELIDQK 594

                          490       500
                   ....*....|....*....|..
gi 1622909118 1761 SEEVQDLKHQLESNVSKQANLE 1782
Cdd:TIGR04523  595 EKEKKDLIKEIEEKEKKISSLE 616
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 352-1132 3.89e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.81  E-value: 3.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  352 HLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQL 431
Cdd:pfam15921   75 HIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHEL 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  432 -------EDQLQQKSKEISQFlnRLPLQQHETASQ---TCFPDVYNEGTQAVTEENIAS----------LQKRVVELENE 491
Cdd:pfam15921  155 eaakclkEDMLEDSNTQIEQL--RKMMLSHEGVLQeirSILVDFEEASGKKIYEHDSMStmhfrslgsaISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  492 ----KGALLLSSIELEELKAENEKlSSQITLLEAQNRIGEADREvSEISIVDDANKRSS--STEESGQDVLENTFSQKHK 565
Cdd:pfam15921  233 isylKGRIFPVEDQLEALKSESQN-KIELLLQQHQDRIEQLISE-HEVEITGLTEKASSarSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  566 ELSVLLLEMKEAQEEIAFLKLQL-QGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVE 644
Cdd:pfam15921  311 QNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKRE 390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  645 KEQASTEHQNR------TSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQIlelelnfhkaqeiyeKN 718
Cdd:pfam15921  391 KELSLEKEQNKrlwdrdTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAI---------------QG 455

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  719 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSvvTELRAQVRQLEMNLAEAERQR-RFDYESQTA 797
Cdd:pfam15921  456 KNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT--ASLQEKERAIEATNAEITKLRsRVDLKLQEL 533

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  798 HHnLLTEQIHslsieakskdvkIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALS 877
Cdd:pfam15921  534 QH-LKNEGDH------------LRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEIN 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  878 QKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKM---VQLNEEKFSLGVEIKTLKEQLNLLSraeeakk 954
Cdd:pfam15921  601 DRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLravKDIKQERDQLLNEVKTSRNELNSLS------- 673

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  955 eqveEDNEVvsgLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELAnlkdqskke 1034
Cdd:pfam15921  674 ----EDYEV---LKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQIT--------- 737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1035 iplseSERGEVEEDKENKEYSEKCVTSKCQEIEIsLKQTISEKEVELEHIRKDlEEKMAAE-EQLQALVKEMNQTLQDKT 1113
Cdd:pfam15921  738 -----AKRGQIDALQSKIQFLEEAMTNANKEKHF-LKEEKNKLSQELSTVATE-KNKMAGElEVLRSQERRLKEKVANME 810

                          810
                   ....*....|....*....
gi 1622909118 1114 NQIDLLQAEISENQVIIQK 1132
Cdd:pfam15921  811 VALDKASLQFAECQDIIQR 829
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1476-1718 5.50e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 5.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1476 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQEE 1555
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1556 RDKLITEMDRsLLENQSLSGSCESLKLALEGltEDKEKLVKEIESLKSSkiaessewQEKHKELQKEYEILLQSYENVSN 1635
Cdd:COG4942     99 LEAQKEELAE-LLRALYRLGRQPPLALLLSP--EDFLDAVRRLQYLKYL--------APARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1636 EAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1715
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247


                   ...
gi 1622909118 1716 GTA 1718
Cdd:COG4942    248 FAA 250
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1424-2918 5.78e-06

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 52.75  E-value: 5.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1424 REKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAAL--ISRK 1501
Cdd:TIGR01612  540 KEIEAGLKESYELAKNWKKLIHEIKKELE----EENEDSIHLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIknISDK 615

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1502 -EALKENKSLQEELSLARDTIEHLTK-SLADVESHVSAQNKEKDRVLGRLA-LLQEERDKLITEMDRSLLENQSLSgsce 1578
Cdd:TIGR01612  616 nEYIKKAIDLKKIIENNNAYIDELAKiSPYQVPEHLKNKDKIYSTIKSELSkIYEDDIDALYNELSSIVKENAIDN---- 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1579 slklaleglTEDKEKLvkeiESLKSSKIAESSEWQEKHKELQKEYeilLQSYENVSNEAERIqhVVEAVRQEKQELYGKL 1658
Cdd:TIGR01612  692 ---------TEDKAKL----DDLKSKIDKEYDKIQNMETATVELH---LSNIENKKNELLDI--IVEIKKHIHGEINKDL 753

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1659 RSTEANKKETEKQLQEAEKEMEEMKEKMRKFakskQQKILELEEE-NDRlraevhpaggtakecmetllSSNASMKEEve 1737
Cdd:TIGR01612  754 NKILEDFKNKEKELSNKINDYAKEKDELNKY----KSKISEIKNHyNDQ--------------------INIDNIKDE-- 807

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1738 RVKMEYETLSKKFQSLMSEKDSLSE---EVQDLKHQLESNVSKQANLEAT--EKHDNQMNVTEEATQSIPGETEDQDSLS 1812
Cdd:TIGR01612  808 DAKQNYDKSKEYIKTISIKEDEIFKiinEMKFMKDDFLNKVDKFINFENNckEKIDSEHEQFAELTNKIKAEISDDKLND 887

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1813 MSTRPACSESVPSE-NSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKE---------------------- 1869
Cdd:TIGR01612  888 YEKKFNDSKSLINEiNKSIEEEYQNINTLKKVDEYIKICENTKESIEKFHNKQNILKEilnknidtikesnlieksykdk 967

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1870 FSQTLENERNAL--------LSQISTKDGEL----KLLQEEV--SKMNLLNQQIQEELSRVTKLketaEEEKDDLEERLM 1935
Cdd:TIGR01612  968 FDNTLIDKINELdkafkdasLNDYEAKNNELikyfNDLKANLgkNKENMLYHQFDEKEKATNDI----EQKIEDANKNIP 1043

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1936 NQLAELNGSIGNYCQDVTDAQIKN-ELLESE-MKNLKKCVSELEEEKQQL----VKEKTKVESEIRKEYLEKIQGAQKEP 2009
Cdd:TIGR01612 1044 NIEIAIHTSIYNIIDEIEKEIGKNiELLNKEiLEEAEINITNFNEIKEKLkhynFDDFGKEENIKYADEINKIKDDIKNL 1123

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2010 GNK--SHAKELQELLKEKQQEVKQLQKdciryqeKISALERTVKALefVQTESQKDLEITKENLAQAVEHRKKAQAELas 2087
Cdd:TIGR01612 1124 DQKidHHIKALEEIKKKSENYIDEIKA-------QINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEI-- 1192

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2088 fKVLLddtqSEAARVLADNLKLKK----ELQSNKESVKSQMKQKDEDLER--RLEQAEEKHLKEKKNMQEKLDALRREKV 2161
Cdd:TIGR01612 1193 -KKLL----NEIAEIEKDKTSLEEvkgiNLSYGKNLGKLFLEKIDEEKKKseHMIKAMEAYIEDLDEIKEKSPEIENEMG 1267

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2162 HLEETIGEIQV--TLNKKDKEIQQVQENLDSTVAQLAafTKSMSSLQDD-RDRVIDEAKKWERKFSDAIQTKEEEIRLKE 2238
Cdd:TIGR01612 1268 IEMDIKAEMETfnISHDDDKDHHIISKKHDENISDIR--EKSLKIIEDFsEESDINDIKKELQKNLLDAQKHNSDINLYL 1345

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2239 ENCSVLkdqlrqmsihmeelkINISRLEHDKQIWEskaqtevqlqqkvcdtlqgENKELLSQLEETRHlyhNSQNELAKL 2318
Cdd:TIGR01612 1346 NEIANI---------------YNILKLNKIKKIID-------------------EVKEYTKEIEENNK---NIKDELDKS 1388

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2319 ESELNILKDQLtdlsnSLEKCKEQKE------NLEGIIrQQEADIQNSKFSYE-QLETDLQASRELT---SRLHEEINMK 2388
Cdd:TIGR01612 1389 EKLIKKIKDDI-----NLEECKSKIEstlddkDIDECI-KKIKELKNHILSEEsNIDTYFKNADENNenvLLLFKNIEMA 1462

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2389 EQKMISLLSGKEEaiqvaiaELRQQHDKEIKELENLLSQEEEENIVLEEeNKKAVDKTNQLMETLNAIKKENIQQKAQLd 2468
Cdd:TIGR01612 1463 DNKSQHILKIKKD-------NATNDHDFNINELKEHIDKSKGCKDEADK-NAKAIEKNKELFEQYKKDVTELLNKYSAL- 1533

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2469 SFVKSMSSLQNDRDRIVGDYQQLE----------ERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLD 2538
Cdd:TIGR01612 1534 AIKNKFAKTKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLKIS 1613

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2539 AELIQYREDLNQVISIK--------DSQQKQLLEAQLQQN------KELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2604
Cdd:TIGR01612 1614 DIKKKINDCLKETESIEkkissfsiDSQDTELKENGDNLNslqeflESLKDQKKNIEDKKKELDELDSEIEKIEIDVDQH 1693

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2605 KRDLS---------------KEIESLKVSVSQLTRQVTA---------LQEEGTLGIYHAQLKVKEEELQRLSALLSS-- 2658
Cdd:TIGR01612 1694 KKNYEigiiekikeiaiankEEIESIKELIEPTIENLISsfntndlegIDPNEKLEEYNTEIGDIYEEFIELYNIIAGcl 1773

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2659 ---SQKRIT--ELEEELVCVQKEAAKKVgEIEDKLKKELKHLhhdagimrnetetaeeRVAELARDLVEMEQKLLMV--- 2730
Cdd:TIGR01612 1774 etvSKEPITydEIKNTRINAQNEFLKII-EIEKKSKSYLDDI----------------EAKEFDRIINHFKKKLDHVndk 1836

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2731 -TKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENS- 2808
Cdd:TIGR01612 1837 fTKEYSKINEGFDDISKSIENVKNSTDE-NLLFDILNKTKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINIQIQNNs 1915

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2809 -LSYLEKLNQQLLSkdeqllHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSA---------AQP 2878
Cdd:TIGR01612 1916 gIDLFDNINIAILS------SLDSEKEDTLKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQdtlniifenQQL 1989

                         1610      1620      1630      1640
                   ....*....|....*....|....*....|....*....|
gi 1622909118 2879 ATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQ 2918
Cdd:TIGR01612 1990 YEKIQASNELKDTLSDLKYKKEKILNDVKLLLHKFDELNK 2029
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1316-1520 5.92e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 5.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1316 KAQLKEIETEKEKLELKISsttsELTKKSEEVFQLQDQINKQGLEIESLKTAShEAEVRAESLQQKLESSQLQiagLEHL 1395
Cdd:COG4913    609 RAKLAALEAELAELEEELA----EAEERLEALEAELDALQERREALQRLAEYS-WDEIDVASAEREIAELEAE---LERL 680

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1396 RELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEmqakEHDERIKQLQVELCEmKQK 1475
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLE----AAEDLARLELRALLE-ERF 755

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909118 1476 PEEIEEESRakQQIQRKLQAaliSRKEALKENKSLQEELSLARDT 1520
Cdd:COG4913    756 AAALGDAVE--RELRENLEE---RIDALRARLNRAEEELERAMRA 795
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1584-2190 6.47e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.94  E-value: 6.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1584 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1663
Cdd:TIGR04523  129 LEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKK 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1664 nKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDrlraevhpaggTAKECMETLLSSNASMKEEVERVKMEY 1743
Cdd:TIGR04523  209 -KIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS-----------NTQTQLNQLKDEQNKIKKQLSEKQKEL 276

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1744 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMStrpacsesv 1823
Cdd:TIGR04523  277 EQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQL--------- 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1824 psENSANPAVSEDVSSHDEINNYLQQIDQLKEriagleeEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMN 1903
Cdd:TIGR04523  348 --KKELTNSESENSEKQRELEEKQNEIEKLKK-------ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ 418

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1904 LLNQQIQEELSRVTKLKETAEEEKDDLEerlmNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKkcvSELEEEKQQL 1983
Cdd:TIGR04523  419 QEKELLEKEIERLKETIIKNNSEIKDLT----NQDSVKELIIKNLDNTRESLETQLKVLSRSINKIK---QNLEQKQKEL 491

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1984 VKEktkvESEIRKEYLEKIQGAQKepgnkshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFvqtesqkd 2063
Cdd:TIGR04523  492 KSK----EKELKKLNEEKKELEEK-------VKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDF-------- 552

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2064 lEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLErRLEQAEEKHL 2143
Cdd:TIGR04523  553 -ELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELE-KAKKENEKLS 630

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1622909118 2144 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDS 2190
Cdd:TIGR04523  631 SIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKESKTKIDD 677
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1737-2352 7.26e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.25  E-value: 7.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1737 ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEAteKHDNQMNVTEEATQSIPGETEDQDSLSMSTR 1816
Cdd:COG1196    221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEA--ELEELRLELEELELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1817 PACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQ 1896
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1897 EEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELngsignycQDVTDAQIKNELLESEMKNLKKCVSEL 1976
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEEL--------EELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1977 EEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISA--LERTVKALE 2054
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLI 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2055 FVQTESQKDLEITKENLAQAVeHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKsqmkqkdEDLERR 2134
Cdd:COG1196    531 GVEAAYEAALEAALAAALQNI-VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGA-------IGAAVD 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2135 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2214
Cdd:COG1196    603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2215 EAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGEN 2294
Cdd:COG1196    683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDL 762

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2295 KELLSQLEETRhlyhnsqNELAKLES-------ELNILKDQLTDLSNSLEKCKEQKENLEGIIRQ 2352
Cdd:COG1196    763 EELERELERLE-------REIEALGPvnllaieEYEELEERYDFLSEQREDLEEARETLEEAIEE 820
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-534 7.70e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 51.86  E-value: 7.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   51 QERLAYAEQLVVELKDIIRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKAKLT---SLNKHIEEMKAQGGTVLLTEPQ 127
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEeleEAEAELAEAEEALLEAEAELAE 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  128 SEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQA 207
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  208 QLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQR------------------KL 269
Cdd:COG1196    457 EEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLaglrglagavavligveaAY 536

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  270 EEHEESLVGRAQVVDLLQQELTAAEQRN-------------------QILSQQLQQIEAEHNTLRNTVETEREESKILLE 330
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEylkaakagratflpldkirARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  331 KMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQN 410
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  411 SKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTcfPDVYNEGTQAVTEENIASLQKRVVELEN 490
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEE--LLEEEALEELPEPPDLEELERELERLER 774

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909118  491 EKGAL----LLSSIELEELKAENEKLSSQI-TLLEA----QNRIGEADREVSE 534
Cdd:COG1196    775 EIEALgpvnLLAIEEYEELEERYDFLSEQReDLEEAretlEEAIEEIDRETRE 827
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
993-1524 8.50e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.96  E-value: 8.50e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  993 KKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDqskkEIPLSESERGEVEEDKEN-----KEYSEKCVTSKCQEIE 1067
Cdd:PRK02224   184 DQRGSLDQLKAQIEEKEEKDLHERLNGLESELAELDE----EIERYEEQREQARETRDEadevlEEHEERREELETLEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1068 IS-LKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTL-------QDKTNQIDLLQAEISENQviiQKLTTSNTD 1139
Cdd:PRK02224   260 IEdLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAglddadaEAVEARREELEDRDEELR---DRLEECRVA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1140 ASDGDSVAlvketvvisppgtDSGEHWKPELEEKILALEKEKEQLQKKLQ---EALTSRKAILKKAQEKERHLREELKQQ 1216
Cdd:PRK02224   337 AQAHNEEA-------------ESLREDADDLEERAEELREEAAELESELEearEAVEDRREEIEELEEEIEELRERFGDA 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1217 KDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESID-----------GKLPSPDQQEWCSP-TPGLEEPLFKATEqhht 1284
Cdd:PRK02224   404 PVDLGNAEDFLEELREERDELREREAELEATLRTARErveeaealleaGKCPECGQPVEGSPhVETIEEDRERVEE---- 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1285 qpvLESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESL 1364
Cdd:PRK02224   480 ---LEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1365 KTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLI 1444
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEI----ERLREKREALAELNDERRERLAEK 632

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1445 KALHTQLEmqAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHL 1524
Cdd:PRK02224   633 RERKRELE--AEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2350-3109 9.68e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 9.68e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2350 IRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEqKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLS--- 2426
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAE-RYQALLKEKREYEGYELLKEKEALERQKEAIERQLAsle 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2427 QEEEENIVLEEENKKAVDKTNQLMETLNA-IKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEErhlsvilEKDQL 2505
Cdd:TIGR02169  251 EELEKLTEEISELEKRLEEIEQLLEELNKkIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE-------DAEER 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2506 IQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNqvisikdsqqkqLLEAQLQQ----NKELKNKYAKLE 2581
Cdd:TIGR02169  324 LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE------------DLRAELEEvdkeFAETRDELKDYR 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2582 EKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYhaQLKVKEEELQRLSALLSSSQK 2661
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKAL--EIKKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2662 RITELEEELVCVQKEAAKKVGEIeDKLKKELKHLHHDAGIMRNETETAEER---VAELARDLVEMEQKLLmvtkenkdLT 2738
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQREL-AEAEAQARASEERVRGGRAVEEVLKASiqgVHGTVAQLGSVGERYA--------TA 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2739 AQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPE-----ENSLSY-- 2811
Cdd:TIGR02169  541 IEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEfdpkyEPAFKYvf 620

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2812 -----LEKL--------NQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQrsaaqp 2878
Cdd:TIGR02169  621 gdtlvVEDIeaarrlmgKYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQ------ 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2879 atslAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQDKTKTFQIMQEELRQENLSW 2954
Cdd:TIGR02169  695 ----SELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEklkeRLEELEEDLSSLEQEIENVKSELKELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2955 QHELHQLRMEKSSWEIHERRMKEQYLMAISDK-DQQVSHLQNLIRELRSSSSQAQPLKVQYQrqaspetsaspDGSQNLI 3033
Cdd:TIGR02169  771 EEDLHKLEEALNDLEARLSHSRIPEIQAELSKlEEEVSRIEARLREIEQKLNRLTLEKEYLE-----------KEIQELQ 839

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 3034 YETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQEL 3109
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
710-915 1.07e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 51.17  E-value: 1.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  710 KAQEIYEKNLDEKAKEISNLNQLIEEFKKNADnnssaFTALSEERDQLLAQVkelsvvTELRAQVRQLEMNLAEAERQRR 789
Cdd:COG3206    175 KALEFLEEQLPELRKELEEAEAALEEFRQKNG-----LVDLSEEAKLLLQQL------SELESQLAEARAELAEAEARLA 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  790 FDYESQTAHHNLLTEQIHSLSIEAKSKdvKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRH----- 864
Cdd:COG3206    244 ALRAQLGSGPDALPELLQSPVIQQLRA--QLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILAsleae 321

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118  865 ---ISSKVEELSQALSQKELEIAKMDQL---LLEKKRDVETLQQTIEEKDQQVTEIS 915
Cdd:COG3206    322 leaLQAREASLQAQLAQLEARLAELPELeaeLRRLEREVEVARELYESLLQRLEEAR 378
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1733-2381 1.09e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.66  E-value: 1.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1733 KEEVERVKMEYE-----------------------------TLSKKFQSLMSEKDSL-------SEEVQDLKHQLESNV- 1775
Cdd:pfam15921   73 KEHIERVLEEYShqvkdlqrrlnesnelhekqkfylrqsviDLQTKLQEMQMERDAMadirrreSQSQEDLRNQLQNTVh 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1776 ----SKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSShdEINNYLQQID 1851
Cdd:pfam15921  153 eleaAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGS--AISKILRELD 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1852 Q----LKERIAGLEEEKQKNKEFSQT-----LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELsrvtklkET 1922
Cdd:pfam15921  231 TeisyLKGRIFPVEDQLEALKSESQNkiellLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQL-------EI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1923 AEEEKDDLEERLMNQLAELNGSIGNYCQDVTDA----QIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1998
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAkrmyEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1999 -----------LEKIQGAQ---KEPGNKSHAKELQELLKEKQQEV-------KQLQKDCI-RYQEKISALERTVKALEFV 2056
Cdd:pfam15921  384 adlhkrekelsLEKEQNKRlwdRDTGNSITIDHLRRELDDRNMEVqrleallKAMKSECQgQMERQMAAIQGKNESLEKV 463

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2057 QTESQKdLEITKENLAQAVEHRKKAQAELASFKVLLDD--------------TQSEAARVLAD-NLKLK----------- 2110
Cdd:pfam15921  464 SSLTAQ-LESTKEMLRKVVEELTAKKMTLESSERTVSDltaslqekeraieaTNAEITKLRSRvDLKLQelqhlknegdh 542

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2111 -KELQSNKESVKSQMKQKDEDLErRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK----KDKEIQQVQ 2185
Cdd:pfam15921  543 lRNVQTECEALKLQMAEKDKVIE-ILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilKDKKDAKIR 621

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2186 EnLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHME--------E 2257
Cdd:pfam15921  622 E-LEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMEtttnklkmQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2258 LKINISRLEHDKQIWESKA-------------QTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNI 2324
Cdd:pfam15921  701 LKSAQSELEQTRNTLKSMEgsdghamkvamgmQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2325 LKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRL 2381
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRL 837
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1310-2231 1.10e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.33  E-value: 1.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-------IESLKTASHEAEVRAESLQQKL 1382
Cdd:pfam01576  103 QHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKErklleerISEFTSNLAEEEEKAKSLSKLK 182

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1383 ESSQLQIAGLE-HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE- 1460
Cdd:pfam01576  183 NKHEAMISDLEeRLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNa 262

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1461 --RIKQLQVELCEMkQKPEEIEEESRAKQQIQRKlqaALISRKEALKenKSLQEELSLARDTIEHLTKSLADVESHVSAQ 1538
Cdd:pfam01576  263 lkKIRELEAQISEL-QEDLESERAARNKAEKQRR---DLGEELEALK--TELEDTLDTTAAQQELRSKREQEVTELKKAL 336

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1539 NKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEgltEDKEKLVKEIESLKSSKI----------AE 1608
Cdd:pfam01576  337 EEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALE---SENAELQAELRTLQQAKQdsehkrkkleGQ 413

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1609 SSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRK 1688
Cdd:pfam01576  414 LQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQ 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1689 FAKSKQQKILELEEEND-RLRAEVHPAGGTAK------------ECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMS 1755
Cdd:pfam01576  494 LEDERNSLQEQLEEEEEaKRNVERQLSTLQAQlsdmkkkleedaGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEK 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1756 EKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQ--------DSLSMSTRPACSES----- 1822
Cdd:pfam01576  574 TKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRaeaearekETRALSLARALEEAleake 653

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1823 -VPSENSANPAVSED-VSSHDEINNYL-----------QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQIStKD 1889
Cdd:pfam01576  654 eLERTNKQLRAEMEDlVSSKDDVGKNVhelerskraleQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFE-RD 732

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1890 GELKLLQEEVSKMNLLNQ--QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSigNYCQDVTDAQIKNelLESEMK 1967
Cdd:pfam01576  733 LQARDEQGEEKRRQLVKQvrELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAA--NKGREEAVKQLKK--LQAQMK 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1968 NLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALE 2047
Cdd:pfam01576  809 DLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLE 888

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2048 RTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQK 2127
Cdd:pfam01576  889 ARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKFKSS 968

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2128 DEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIgeIQVTLNKKDKEiqQVQENLDSTVAQLAAFTKSMSSLQD 2207
Cdd:pfam01576  969 IAALEAKIAQLEEQLEQESRERQAANKLVRRTEKKLKEVL--LQVEDERRHAD--QYKDQAEKGNSRMKQLKRQLEEAEE 1044

                          970       980
                   ....*....|....*....|....
gi 1622909118 2208 DRDRVIDEAKKWERKFSDAIQTKE 2231
Cdd:pfam01576 1045 EASRANAARRKLQRELDDATESNE 1068
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1314-2161 1.24e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 1.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1314 QIKAQLKEIETEKEKLELKiSSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES----SQLQI 1389
Cdd:TIGR00606  225 QITSKEAQLESSREIVKSY-ENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKvfqgTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1390 AGLEHLR------------ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1457
Cdd:TIGR00606  304 NDLYHNHqrtvrekerelvDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1458 HDERIKQLQVELCEMKQkpEEIEEESRAKQQIQRKLQAALISRKEALKEnksLQEELSLARDTIEHLTKSLADVESHVSA 1537
Cdd:TIGR00606  384 RGPFSERQIKNFHTLVI--ERQEDEAKTAAQLCADLQSKERLKQEQADE---IRDEKKGLGRTIELKKEILEKKQEELKF 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1538 QNKEKDRVLGrlallqeerdklitEMDRSLLENQSLSGSCESLKLALE-GLTEDKEKLVKEIESLKSSKIAESSEWQEKH 1616
Cdd:TIGR00606  459 VIKELQQLEG--------------SSDRILELDQELRKAERELSKAEKnSLTETLKKEVKSLQNEKADLDRKLRKLDQEM 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1617 KELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLrSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQk 1696
Cdd:TIGR00606  525 EQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLL-GYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELAS- 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1697 ileLEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEV--ERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESN 1774
Cdd:TIGR00606  603 ---LEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESdlERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSC 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1775 VSKQANLEATEKHDNQM-NVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQL 1853
Cdd:TIGR00606  680 CPVCQRVFQTEAELQEFiSDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD 759

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1854 KERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQE-ELSRVTKLKETAEEEKDDLEE 1932
Cdd:TIGR00606  760 IQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGsDLDRTVQQVNQEKQEKQHELD 839

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1933 RLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNK 2012
Cdd:TIGR00606  840 TVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLE 919

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2013 SHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKEN--------LAQAVEHRKKAQAE 2084
Cdd:TIGR00606  920 KDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETelntvnaqLEECEKHQEKINED 999

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2085 LASFKVLLdDTQSEAARVLADNLKLKK---ELQSNKESVKSQMKQKDEDLERRLEQAEEKhlkekknMQEKLDALRREKV 2161
Cdd:TIGR00606 1000 MRLMRQDI-DTQKIQERWLQDNLTLRKrenELKEVEEELKQHLKEMGQMQVLQMKQEHQK-------LEENIDLIKRNHV 1071
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1315-1710 1.34e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1315 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKtaSHEAEVRAESLQQKLESSQlqiaglEH 1394
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLN--NQKEQDWNKELKSELKNQE------KK 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKalhtQLEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:TIGR04523  323 LEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNLESQINDLES 398

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEESrakQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQE 1554
Cdd:TIGR04523  399 KIQNQEKLN---QQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSR 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1555 ERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKEL-QKEYEILLQSYENV 1633
Cdd:TIGR04523  476 SINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIsDLEDELNKDDFELK 555

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1634 SNEaeriqhvVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAE 1710
Cdd:TIGR04523  556 KEN-------LEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKE 625
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2118-2825 1.41e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2118 ESVKSQMKQKDEDLERRLEQAEEKHLKEK--------------KNMQEKLDAL----RREKVHLEETIGEIQVTLNKKDK 2179
Cdd:pfam15921   77 ERVLEEYSHQVKDLQRRLNESNELHEKQKfylrqsvidlqtklQEMQMERDAMadirRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2180 EIQQVQENLDSTVAQLAAFTKSMSS----LQDDRDRVIDEAKKWERKFSDAIQTKEEEIRlkeENCSVLKDQLRQMSIHM 2255
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLShegvLQEIRSILVDFEEASGKKIYEHDSMSTMHFR---SLGSAISKILRELDTEI 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2256 EELKINISRLEHDKQIWESKAQTEVQL----QQKVCDTLQGENKELLSQLEETRHlyhNSQNELAKLESELNILKDQLTD 2331
Cdd:pfam15921  234 SYLKGRIFPVEDQLEALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKAS---SARSQANSIQSQLEIIQEQARN 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2332 lSNSLEKCkeQKENLEGIIRQQEADIQNSKFSYEQLETDLQ-----ASRELTSRLHEEINMKE---------QKMISLLS 2397
Cdd:pfam15921  311 -QNSMYMR--QLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlANSELTEARTERDQFSQesgnlddqlQKLLADLH 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2398 GKEEAIQ-----------------VAIAELRQQHDK---EIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIK 2457
Cdd:pfam15921  388 KREKELSlekeqnkrlwdrdtgnsITIDHLRRELDDrnmEVQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSSLT 467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2458 KENIQQKAQLDSFVKSMSSLQ---NDRDRIVGDYQqleerhlSVILEKDQLIQEAAAENNKLK-------EEIRGLRSHM 2527
Cdd:pfam15921  468 AQLESTKEMLRKVVEELTAKKmtlESSERTVSDLT-------ASLQEKERAIEATNAEITKLRsrvdlklQELQHLKNEG 540

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2528 DDLNSENAKLDAELIQYREDlNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSnaLQEEKRD 2607
Cdd:pfam15921  541 DHLRNVQTECEALKLQMAEK-DKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK--ILKDKKD 617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2608 lsKEIESLKVSVSQLTRQVTALQEEGTLGIyHAQLKVKEEELQRLSALlSSSQKRITELEEELVCVQKEAAKKVGEIE-- 2685
Cdd:pfam15921  618 --AKIRELEARVSDLELEKVKLVNAGSERL-RAVKDIKQERDQLLNEV-KTSRNELNSLSEDYEVLKRNFRNKSEEMEtt 693

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2686 -DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDE 2764
Cdd:pfam15921  694 tNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNK 773

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909118 2765 LKRKYDASLKELAQLKEQQGLLnRERHALLSETTFSMDLP-EENSLSYLEklNQQLLSKDEQ 2825
Cdd:pfam15921  774 LSQELSTVATEKNKMAGELEVL-RSQERRLKEKVANMEVAlDKASLQFAE--CQDIIQRQEQ 832
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 981-1783 1.49e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  981 SKEELQHEFDLLKKENEQRKRKLQAaliNRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVT 1060
Cdd:TIGR02169  238 QKEAIERQLASLEEELEKLTEEISE---LEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKE 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1061 SKCQEIEISLKQTISE---KEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQI-------DLLQAEISENQVII 1130
Cdd:TIGR02169  315 RELEDAEERLAKLEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELeevdkefAETRDELKDYREKL 394

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1131 QKLTtSNTDASDGDSVALVKETVVISPPGTDSGEHWKpELEEKILALEKEKEQLQKKLQEA---LTSRKAILKKAQEKER 1207
Cdd:TIGR02169  395 EKLK-REINELKRELDRLQEELQRLSEELADLNAAIA-GIEAKINELEEEKEDKALEIKKQewkLEQLAADLSKYEQELY 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1208 HLREELKQQKDDYNRLQEQFDEQSKenenigdqlrQLQIQVRESIDGKLPSPDQQEWCSPTPGLEEPLFKATEQHhtQPV 1287
Cdd:TIGR02169  473 DLKEEYDRVEKELSKLQRELAEAEA----------QARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERY--ATA 540

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1288 LES-------NLCPDWPSHSEDASAL----QGGTS----VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQlqd 1352
Cdd:TIGR02169  541 IEVaagnrlnNVVVEDDAVAKEAIELlkrrKAGRAtflpLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFK--- 617

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1353 QINKQGLEIESLKTA-SHEAEVRAESLQQKL-ESSQLQIAGleHLRELQPELDELQKlisekEEDVSYLSGQLREKEAAL 1430
Cdd:TIGR02169  618 YVFGDTLVVEDIEAArRLMGKYRMVTLEGELfEKSGAMTGG--SRAPRGGILFSRSE-----PAELQRLRERLEGLKREL 690

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1431 TKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALisrkealKENKSL 1510
Cdd:TIGR02169  691 SSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVK-------SELKEL 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1511 QEELSLARDTIEHLTKSLADVESHvsaqnkekdrvlgrlaLLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTED 1590
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLEAR----------------LSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1591 KEKLVKEIESLKSSKIaessEWQEKHKELQKEyeillqsyenvsneaeriqhvVEAVRQEKQELYGKLRSTEANKKETEK 1670
Cdd:TIGR02169  828 KEYLEKEIQELQEQRI----DLKEQIKSIEKE---------------------IENLNGKKEELEEELEELEAALRDLES 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1671 QLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLrAEVHPAGGTAKECMETLLSSNASMKEEVERVkMEYETLSKKF 1750
Cdd:TIGR02169  883 RLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL-SELKAKLEALEEELSEIEDPKGEDEEIPEEE-LSLEDVQAEL 960

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1622909118 1751 QSLMSEKDSLS-------EEVQDLKHQLESNVSKQANLEA 1783
Cdd:TIGR02169  961 QRVEEEIRALEpvnmlaiQEYEEVLKRLDELKEKRAKLEE 1000
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1300-2053 1.57e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.13  E-value: 1.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1300 SEDASALQGGTSVAQIKAQLKEIETEKEKL---ELKISSTTSELTKKSEEVFQLQDQINKQGLEIESL--KTASHEAEVR 1374
Cdd:pfam02463  216 KEKLELEEEYLLYLDYLKLNEERIDLLQELlrdEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLqeEELKLLAKEE 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1375 AESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQ 1454
Cdd:pfam02463  296 EELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEEL 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1455 AKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESH 1534
Cdd:pfam02463  376 LAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEK 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1535 VSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQE 1614
Cdd:pfam02463  456 QELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLG 535

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1615 KHKELQKEYEILLQSYEN--VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKS 1692
Cdd:pfam02463  536 VAVENYKVAISTAVIVEVsaTADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEA 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1693 KQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLE 1772
Cdd:pfam02463  616 DEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1773 SNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1852
Cdd:pfam02463  696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1853 LKERIAGLEEEKQ--KNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDL 1930
Cdd:pfam02463  776 LAEEREKTEKLKVeeEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEE 855

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1931 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPG 2010
Cdd:pfam02463  856 LERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE 935

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1622909118 2011 NKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKAL 2053
Cdd:pfam02463  936 EPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLM 978
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1315-1926 1.82e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.82e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1315 IKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAEslqqklessqlqiagleh 1394
Cdd:TIGR04523  108 INSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKE------------------ 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1395 lrELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALhTQLEMQAKEHDERIKQLQVELCEMKQ 1474
Cdd:TIGR04523  170 --ELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQI-SELKKQNNQLKDNIEKKQQEINEKTT 246

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1475 KPEEIEEesrakqqiqrKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLALLQ- 1553
Cdd:TIGR04523  247 EISNTQT----------QLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSEl 316

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1554 EERDKLITEMDRSLLENQSLSGSceslklaLEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENV 1633
Cdd:TIGR04523  317 KNQEKKLEEIQNQISQNNKIISQ-------LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1634 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEvhp 1713
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESL--- 466

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1714 aggtaKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNV 1793
Cdd:TIGR04523  467 -----ETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKIS 541

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1794 TEEATQSIPGETEDQDSLSmstrpacsesvpsensanpavsedvsshDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1873
Cdd:TIGR04523  542 DLEDELNKDDFELKKENLE----------------------------KEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQ 593

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 1874 LENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEE 1926
Cdd:TIGR04523  594 KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQE 646
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1359-1997 1.86e-05

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 50.67  E-value: 1.86e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1359 LEIESLktasheaEVRAESLQQKLESSQLQIAGLEHLRE-LQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI 1437
Cdd:PRK01156   159 LEINSL-------ERNYDKLKDVIDMLRAEISNIDYLEEkLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAM 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1438 IEQEDLIKALH---------TQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENK 1508
Cdd:PRK01156   232 DDYNNLKSALNelssledmkNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENKK 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1509 SLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRvlgrlallQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLT 1588
Cdd:PRK01156   312 QILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSR--------YDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYS 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1589 EDKEKLVKEIESLKSSKIAESSewqekhkELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrstEANKKET 1668
Cdd:PRK01156   384 KNIERMSAFISEILKIQEIDPD-------AIKKELNEINVKLQDISSKVSSLNQRIRALRENLDEL-------SRNMEML 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1669 EKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNasmKEEVERVKMEYETLSK 1748
Cdd:PRK01156   450 NGQSVCPVCGTTLGEEKSNHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLE---SEEINKSINEYNKIES 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1749 KFQSLMSEKDSLSE-EVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSEN 1827
Cdd:PRK01156   527 ARADLEDIKIKINElKDKHDKYEEIKNRYKSLKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEI 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1828 SANpavSEDVSSHDEinNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQ 1907
Cdd:PRK01156   607 EIG---FPDDKSYID--KSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIED 681

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1908 QIQEELSRVTKLKeTAEEEKDDLEERLMNQLAELNGSIGNycqdvtdaqiKNELLESeMKNLKKCVSELEEEKQQLvkEK 1987
Cdd:PRK01156   682 NLKKSRKALDDAK-ANRARLESTIEILRTRINELSDRIND----------INETLES-MKKIKKAIGDLKRLREAF--DK 747

                          650
                   ....*....|
gi 1622909118 1988 TKVESEIRKE 1997
Cdd:PRK01156   748 SGVPAMIRKS 757
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1312-1780 2.10e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.15  E-value: 2.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1312 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1391
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1392 LEHLRELQPELDELQKLISEKEEdvsylsgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAK----EHDERIKQLQV 1467
Cdd:COG4717    128 LPLYQELEALEAELAELPERLEE--------LEERLEELRELEEELEELEAELAELQEELEELLEqlslATEEELQDLAE 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1468 ELCEMKQKPEEIEEESRAKQQIQRKLQAA---LISRKEALKENKSLQEELSLAR----------------DTIEHLTKSL 1528
Cdd:COG4717    200 ELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKEARLLLLiaaallallglggsllSLILTIAGVL 279

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1529 ADVESHVSAQNKEKDRvlgRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE 1608
Cdd:COG4717    280 FLVLGLLALLFLLLAR---EKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREA 356

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1609 SSEWQE-KHKELQKEYEILLQSYeNVSNEAERIQHVVEAvrQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMR 1687
Cdd:COG4717    357 EELEEElQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE 433

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1688 kfAKSKQQKILELEEENDRLRAEVhpagGTAKECMETLLSSN--ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQ 1765
Cdd:COG4717    434 --LEELEEELEELEEELEELREEL----AELEAELEQLEEDGelAELLQELEELKAELRELAEEWAALKLALELLEEARE 507

                          490
                   ....*....|....*
gi 1622909118 1766 DLKHQLESNVSKQAN 1780
Cdd:COG4717    508 EYREERLPPVLERAS 522
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1578-2171 2.12e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 2.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1578 ESLKLALEGLTEDKEKLVKEIESLKsskiAESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGK 1657
Cdd:COG1196    228 ELLLLKLRELEAELEELEAELEELE----AELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQD 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1658 LRSTEANKKETEKQLQEAekemeemkekmrkfakskQQKILELEEENDRLRAEvhpaggtakecMETLLSSNASMKEEVE 1737
Cdd:COG1196    304 IARLEERRRELEERLEEL------------------EEELAELEEELEELEEE-----------LEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1738 RVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIpgETEDQDSLSMSTRP 1817
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER--LEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1818 ACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELK--LL 1895
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEgvKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1896 QEEVSKMNLLNQQIQEELSRVtklketaEEEKDDLEERLMNQLAELNgsignycqdVTDAQIKNELLESEMKNLKKCVSE 1975
Cdd:COG1196    513 ALLLAGLRGLAGAVAVLIGVE-------AAYEAALEAALAAALQNIV---------VEDDEVAAAAIEYLKAAKAGRATF 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1976 LEEEKQQlvKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEF 2055
Cdd:COG1196    577 LPLDKIR--ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGE 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2056 VQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRL 2135
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1622909118 2136 EQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQ 2171
Cdd:COG1196    735 EELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2590-2796 2.19e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 2.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2590 ANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEgtLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEE 2669
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR--IAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2670 LVCVQKEAAKKVGEI-----EDKLK-----KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTA 2739
Cdd:COG4942     99 LEAQKEELAELLRALyrlgrQPPLAlllspEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2740 QIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLNRERHALLSE 2796
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1172-1401 2.77e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 2.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1172 EKILALEKEKEQLQKKLQEAltsrKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVREs 1251
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAEL----EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE- 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1252 IDGKLpspDQQEwcsptpGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQGGTS------VAQIKAQLKEIETE 1325
Cdd:COG4942     95 LRAEL---EAQK------EELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAparreqAEELRADLAELAAL 165

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 1326 KEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPE 1401
Cdd:COG4942    166 RAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PTZ00121 PTZ00121
MAEBL; Provisional
 948-1618 3.24e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 3.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  948 RAEEAKKEQVEEDNEVVSGLK--QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELA 1025
Cdd:PTZ00121  1183 KAEEVRKAEELRKAEDARKAEaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARM 1262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1026 NLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEE-QLQALVKE 1104
Cdd:PTZ00121  1263 AHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAaKKKAEEAK 1342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1105 MNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNtDASDGDSVALVKETVVISPPGTDSGEHWKPELEE--KILALEKEKE 1182
Cdd:PTZ00121  1343 KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE-AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElkKAAAAKKKAD 1421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1183 QLQKKLQEAltsRKAILKKAQEKERHLREELKQQKDDYNRLQEQfdEQSKENENIGDQLRQLQIQVRESIDGKLPSPDQQ 1262
Cdd:PTZ00121  1422 EAKKKAEEK---KKADEAKKKAEEAKKADEAKKKAEEAKKAEEA--KKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1263 EWCSPTPGLEEPLFKATEQHHTQPvlesnlcpdwpshsedasalqggtsvAQIKAQLKEIETEKEKLELKisstTSELTK 1342
Cdd:PTZ00121  1497 KKADEAKKAAEAKKKADEAKKAEE--------------------------AKKADEAKKAEEAKKADEAK----KAEEKK 1546

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1343 KSEEVFQLQDQinKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQ 1422
Cdd:PTZ00121  1547 KADELKKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEE 1624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1423 LREKEAALTKI-QTEIIEQEDLIKAlhTQLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRK 1501
Cdd:PTZ00121  1625 LKKAEEEKKKVeQLKKKEAEEKKKA--EELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAK 1702

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1502 EALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVlgrLALLQEERDKLITEMDRSLLENQSLSGSCESLK 1581
Cdd:PTZ00121  1703 KAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA---EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEA 1779

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1622909118 1582 LALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKE 1618
Cdd:PTZ00121  1780 VIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKE 1816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 37-535 4.13e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.55  E-value: 4.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   37 ESDMEFNNTTQEDVQERLAYAEQLVVELkdiiRQKDVQLQQKDEALQEEKKAADNKIKKLKLHAKAKLTSLNKHIEEMKA 116
Cdd:COG1196    301 EQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAE 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  117 QggtvlltepqsEEQLSKHDKSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQ 196
Cdd:COG1196    377 A-----------EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  197 EKEELISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEHEESL 276
Cdd:COG1196    446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGA 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  277 VGR-AQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLE 355
Cdd:COG1196    526 VAVlIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  356 QLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQL 435
Cdd:COG1196    606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  436 QQKSKEISQFLNRLPLQQHETASQTcfpdvyNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ 515
Cdd:COG1196    686 ERLAEEELELEEALLAEEEEERELA------EAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                          490       500
                   ....*....|....*....|
gi 1622909118  516 ITLLEAQNRIGEADREVSEI 535
Cdd:COG1196    760 PDLEELERELERLEREIEAL 779
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1303-1711 5.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 5.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1303 ASALQGGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLE-IESLKTASHEAEVRAESLQQK 1381
Cdd:COG4913    281 LRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLEREIERLERELEERERR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1382 LESSQLQIAGLEH-LRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE 1460
Cdd:COG4913    361 RARLEALLAALGLpLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1461 RIKQLQVELCE---------------MKQKPEE------IE-------------------------------------EE 1482
Cdd:COG4913    441 RLLALRDALAEalgldeaelpfvgelIEVRPEEerwrgaIErvlggfaltllvppehyaaalrwvnrlhlrgrlvyerVR 520

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1483 SRAKQQIQRKLQAALISRKEALKENKS---LQEELSLARD-----------------TIEHLTKSLADVESHVSAQNKEK 1542
Cdd:COG4913    521 TGLPDPERPRLDPDSLAGKLDFKPHPFrawLEAELGRRFDyvcvdspeelrrhpraiTRAGQVKGNGTRHEKDDRRRIRS 600

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 DRVLG-----RLALLQEERDKL---ITEMDRSLLENQSLSGSCESLKLALEGLTE------DKEKLVKEIESLKS--SKI 1606
Cdd:COG4913    601 RYVLGfdnraKLAALEAELAELeeeLAEAEERLEALEAELDALQERREALQRLAEyswdeiDVASAEREIAELEAelERL 680

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1607 AESSEW----QEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEM 1682
Cdd:COG4913    681 DASSDDlaalEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG 760

                          490       500
                   ....*....|....*....|....*....
gi 1622909118 1683 KEKMRKFAKSKQQKILELEEENDRLRAEV 1711
Cdd:COG4913    761 DAVERELRENLEERIDALRARLNRAEEEL 789
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 204-964 7.19e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 7.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  204 TLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLhEDELLQLVTQADVETEMQQklRVLQRKLEEHEESLVGRAQVV 283
Cdd:TIGR02169  234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEI-EQLLEELNKKIKDLGEEEQ--LRVKEKIGELEAEIASLERSI 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  284 DLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQE--------------- 348
Cdd:TIGR02169  311 AEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEvdkefaetrdelkdy 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  349 ----------------EMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSK 412
Cdd:TIGR02169  391 rekleklkreinelkrELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  413 LLQDKdeqavqsaQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAV---TEENIASLQKRVVELE 489
Cdd:TIGR02169  471 LYDLK--------EEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIE 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  490 NEKGALLLSSIELEELKAE------NEKLSSQITLLEAqNRIGEADREVSEISivddankrssstEESGQDVLEN--TFS 561
Cdd:TIGR02169  543 VAAGNRLNNVVVEDDAVAKeaiellKRRKAGRATFLPL-NKMRDERRDLSILS------------EDGVIGFAVDlvEFD 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  562 QKHKELSVLLLEMKEAQEEIaflklqlqgkraeEGDHEVLDQKEMKQMEGEGIAP---IKMEVFLEDTGQNFPLMPNEES 638
Cdd:TIGR02169  610 PKYEPAFKYVFGDTLVVEDI-------------EAARRLMGKYRMVTLEGELFEKsgaMTGGSRAPRGGILFSRSEPAEL 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  639 SLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKN 718
Cdd:TIGR02169  677 QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  719 LDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKElsvvtELRAQVRQLEMNLAEAERQRrfdyesqtah 798
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS-----KLEEEVSRIEARLREIEQKL---------- 821

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  799 hNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQ 878
Cdd:TIGR02169  822 -NRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRE 900

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  879 KELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEkMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVE 958
Cdd:TIGR02169  901 LERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQ 979


                   ....*.
gi 1622909118  959 EDNEVV 964
Cdd:TIGR02169  980 EYEEVL 985
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2225-2989 7.29e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.89  E-value: 7.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2225 DAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEET 2304
Cdd:TIGR00606  224 DQITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDEQL 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2305 RHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEgiIRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEE 2384
Cdd:TIGR00606  304 NDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELL--VEQGRLQLQADRHQEHIRARDSLI---QSLATRLE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2385 INMKEQKMISllsgkEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQK 2464
Cdd:TIGR00606  379 LDGFERGPFS-----ERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2465 AQLDSFVKSMSSLQNDRDRIVGDYQQL--EERHLSvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE-- 2540
Cdd:TIGR00606  454 EELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtt 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2541 -------LIQYREDLNQVISIKDSQQKQLLEAQL---QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSK 2610
Cdd:TIGR00606  533 trtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINN 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2611 EIESLKVSVSQLTRQV----TALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKeAAKKVGEIED 2686
Cdd:TIGR00606  613 ELESKEEQLSSYEDKLfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCP-VCQRVFQTEA 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2687 KLKKELKHLHHDAGIMRNETETAEERVAELARD------LVEMEQKLL-MVTKENKDLTAQIQSFGRSMSSLQNSRDHAN 2759
Cdd:TIGR00606  692 ELQEFISDLQSKLRLAPDKLKSTESELKKKEKRrdemlgLAPGRQSIIdLKEKEIPELRNKLQKVNRDIQRLKNDIEEQE 771

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2760 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQ 2839
Cdd:TIGR00606  772 TLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKL 851

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2840 VQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ-INQ 2918
Cdd:TIGR00606  852 IQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEElISS 931

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 2919 EITELRPLKAQLQEYQDKTKT--------FQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2989
Cdd:TIGR00606  932 KETSNKKAQDKVNDIKEKVKNihgymkdiENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQ 1010
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1837-2052 8.28e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 8.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1837 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEvskMNLLNQQIQEELSRV 1916
Cdd:COG4942     16 AAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE---LAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1917 TKLKETAEEEKDDLEERL------------------------------MNQLAE-LNGSIGNYCQDVTDAQIKNELLESE 1965
Cdd:COG4942     93 AELRAELEAQKEELAELLralyrlgrqpplalllspedfldavrrlqyLKYLAPaRREQAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1966 MKNLKKCVSELEEEKQQLVKEKTKVESEIrkeylekiqgaqkepgnkshaKELQELLKEKQQEVKQLQKDCIRYQEKISA 2045
Cdd:COG4942    173 RAELEALLAELEEERAALEALKAERQKLL---------------------ARLEKELAELAAELAELQQEAEELEALIAR 231


                   ....*..
gi 1622909118 2046 LERTVKA 2052
Cdd:COG4942    232 LEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2686-2912 9.43e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2686 DKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDEL 2765
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2766 KRKYDASLKELAQLKEQQGLLnrerhALLSETTFSMDLpeeNSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSK 2845
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLA-----LLLSPEDFLDAV---RRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2846 AMASLQNERDHLWNELEKFRKSEEGKQRSAAQpatslaEVQSLKKAMSSLQNDRDRLLKELKNLQQQ 2912
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEK------ELAELAAELAELQQEAEELEALIARLEAE 235
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2016-2197 9.93e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 9.93e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2016 KELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELA--------- 2086
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAellralyrl 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2087 ----SFKVLLD-DTQSEAARVLADNLKLKKELQSNKESVKSQmKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKV 2161
Cdd:COG4942    117 grqpPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRAD-LAELAALRAELEAERAELEALLAELEEERAALEALKA 195

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909118 2162 HLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAA 2197
Cdd:COG4942    196 ERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
708-1222 1.10e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.37  E-value: 1.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  708 FHKAQeiyeknldeKAKEISNLNQLIEEF-------KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEmn 780
Cdd:COG4913    197 LHKTQ---------SFKPIGDLDDFVREYmleepdtFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYA-- 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  781 lAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAE 860
Cdd:COG4913    266 -AARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  861 R--------VRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSL 932
Cdd:COG4913    345 ReierlereLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELREL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  933 GVEIKTLKE-QLNLLSRAEEAKKE-------------------QVEEDNE------------------------------ 962
Cdd:COG4913    425 EAEIASLERrKSNIPARLLALRDAlaealgldeaelpfvgeliEVRPEEErwrgaiervlggfaltllvppehyaaalrw 504

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  963 -------------VVSGLKQNYDEMS--PAGLISK-------------EELQHEFDLLKKENEQRKRKLQAAL------- 1007
Cdd:COG4913    505 vnrlhlrgrlvyeRVRTGLPDPERPRldPDSLAGKldfkphpfrawleAELGRRFDYVCVDSPEELRRHPRAItragqvk 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1008 -------------INRKELL-----QRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEI- 1068
Cdd:COG4913    585 gngtrhekddrrrIRSRYVLgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVa 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1069 SLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQT---LQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDS 1145
Cdd:COG4913    665 SAEREIAELEAELERLDASSDDLAALEEQLEELEAELEELeeeLDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLAR 744

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1146 VALVketvvisppgtdsgehwkPELEEKILALEKEKeqLQKKLQEALTSRkaiLKKAQEKERHLREELKQQKDDYNR 1222
Cdd:COG4913    745 LELR------------------ALLEERFAAALGDA--VERELRENLEER---IDALRARLNRAEEELERAMRAFNR 798
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2451-2669 1.12e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2451 ETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERhlsvILEKDQLIQEAAAENNKLKEEIRGLRSHMDDL 2530
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERR----IAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2531 NSENAKLDAELIQY---------REDLNQVISIKDSQQ--------KQLLEAQLQQNKELKNKYAKLEEKLKESEEANED 2593
Cdd:COG4942     96 RAELEAQKEELAELlralyrlgrQPPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 2594 LQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQeegtlgiyhAQLKVKEEELQRLSALLSSSQKRITELEEE 2669
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELA---------AELAELQQEAEELEALIARLEAEAAAAAER 242
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2704-2932 1.21e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2704 NETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQ 2783
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2784 gllnRERHALLSETtfsmdlpeensLSYLEKLNQQllsKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEK 2863
Cdd:COG4942    100 ----EAQKEELAEL-----------LRALYRLGRQ---PPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 2864 FRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKEL----KNLQQQYLQINQEITELRPLKAQLQE 2932
Cdd:COG4942    162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLekelAELAAELAELQQEAEELEALIARLEA 234
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 716-913 1.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 1.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  716 EKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKelsvvtELRAQVRQLEMNLAEAERQRRFDYESQ 795
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIR------ALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  796 TAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQA 875
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1622909118  876 LSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTE 913
Cdd:COG4942    180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAE 217
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 835-1131 1.28e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.61  E-value: 1.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  835 SEQSTLIRSLQSQ--LQNKESEVLEGAERVRHISSKVEELSQALS--QKELEIAKMDQLLLE--KKRDVETLQQTIEEKD 908
Cdd:PRK05771    16 SYKDEVLEALHELgvVHIEDLKEELSNERLRKLRSLLTKLSEALDklRSYLPKLNPLREEKKkvSVKSLEELIKDVEEEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  909 QQVTEISFSMTEKMVQLNEEKFSLGVEIKTLK--EQLNLlsraeEAKKEQveeDNEVVSGLkqnydemspAGLISKEELQ 986
Cdd:PRK05771    96 EKIEKEIKELEEEISELENEIKELEQEIERLEpwGNFDL-----DLSLLL---GFKYVSVF---------VGTVPEDKLE 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  987 HEFDLLKKENE----QRKRKLQAALINRKELLQRVsrlEEELANLkDQSKKEIPlsesERGEVEEdkenkEYSEkcvtsk 1062
Cdd:PRK05771   159 ELKLESDVENVeyisTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE----EEGTPSE-----LIRE------ 219

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1063 cqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQidLLQAEISENQVIIQ 1131
Cdd:PRK05771   220 -------IKEELEEIEKERESLLEELKELAKKYLEELLALYEYLEIELERAEA--LSKFLKTDKTFAIE 279
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2308-2913 1.37e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 1.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2308 YHNSQNELAKLESELNILKDqltdlsnSLEKCKEQKENLEGIIRQQEAdiqnskfsyeqletdlqasrELTSRLHEeinm 2387
Cdd:PRK03918   160 YENAYKNLGEVIKEIKRRIE-------RLEKFIKRTENIEELIKEKEK--------------------ELEEVLRE---- 208

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2388 keqkmISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKEniqqKAQL 2467
Cdd:PRK03918   209 -----INEISSELPELREELEKLEKEV-KELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKE----IEEL 278

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2468 DSFVKSMSSLQNDRDRivgdYQQLEERHLSVILEKDQLIQEAAaennKLKEEIRGLRSHMDDLNSENAKLDAELIQYRED 2547
Cdd:PRK03918   279 EEKVKELKELKEKAEE----YIKLSEFYEEYLDELREIEKRLS----RLEEEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2548 LNQVISIKDSQQK-QLLEAQLQQNKELKNKYAKL-----EEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQ 2621
Cdd:PRK03918   351 EKRLEELEERHELyEEAKAKKEELERLKKRLTGLtpeklEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE 430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2622 LT----------RQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL-----VCVQKEAAKKVGEIED 2686
Cdd:PRK03918   431 LKkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLkkeseLIKLKELAEQLKELEE 510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2687 KLKK-----------ELKHLHHDAGIMRNETETAE---ERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSmsslq 2752
Cdd:PRK03918   511 KLKKynleelekkaeEYEKLKEKLIKLKGEIKSLKkelEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE----- 585

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2753 nSRDHANEELDELKRKYDASLKELAQLKEQQGLLNR-ERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHlss 2831
Cdd:PRK03918   586 -SVEELEERLKELEPFYNEYLELKDAEKELEREEKElKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEY--- 661

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2832 qlEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRlLKELKNLQQ 2911
Cdd:PRK03918   662 --EELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALERVEELREK-VKKYKALLK 738


                   ..
gi 1622909118 2912 QY 2913
Cdd:PRK03918   739 ER 740
PTZ00121 PTZ00121
MAEBL; Provisional
 867-1251 1.39e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 1.39e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  867 SKVEELSQALSQKELEIAKMDQlllEKKRDVETLQQTIEEKDQQVTEISFSMTEKMvqlneekfslgvEIKTLKEQLNLL 946
Cdd:PTZ00121  1366 AEAAEKKKEEAKKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAKK------------KADEAKKKAEEK 1430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  947 SRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAalinrKELLQRVSRLEEELAN 1026
Cdd:PTZ00121  1431 KKADEAKK-KAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEA-----KKKAEEAKKKADEAKK 1504

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1027 LKDQSKKEIPLSESERG-EVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEM 1105
Cdd:PTZ00121  1505 AAEAKKKADEAKKAEEAkKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAE 1584

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1106 NQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKEtvvisppgtdsgEHWKPELEEKILALEKEKEQLQ 1185
Cdd:PTZ00121  1585 EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEE------------EKKKVEQLKKKEAEEKKKAEEL 1652

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 1186 KKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRES 1251
Cdd:PTZ00121  1653 KKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718
46 PHA02562
endonuclease subunit; Provisional
 1841-2001 1.40e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1841 DEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKL-------------LQEEVSKMNLLNQ 1907
Cdd:PHA02562   227 EEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMyekggvcptctqqISEGPDRITKIKD 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1908 QIQEELSRVTKLKETAEEEKDDLEERLMNQ--LAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVK 1985
Cdd:PHA02562   307 KLKELQHSLEKLDTAIDELEEIMDEFNEQSkkLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386

                          170
                   ....*....|....*.
gi 1622909118 1986 EKTKVESEIRKEYLEK 2001
Cdd:PHA02562   387 ELDKIVKTKSELVKEK 402
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1584-1996 1.41e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1584 LEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEillqSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1663
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE----EYAELQEELEELEEELEELEAELEELREELEKLEK 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1664 NKKETEKQLQEAEKEMEEMKEKMR-KFAKSKQQKILELEEENDRLRAEVHPAggtAKECMETLLSSNASMKEEVERVKME 1742
Cdd:COG4717    124 LLQLLPLYQELEALEAELAELPERlEELEERLEELRELEEELEELEAELAEL---QEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1743 YETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPA---- 1818
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAgvlf 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1819 --------CSESVPSENSANPAVSEDVSSHDEINNYLQQI--DQLKERIAGLEEEKQKNKEFSQTLEnERNALLSQISTK 1888
Cdd:COG4717    281 lvlgllalLFLLLAREKASLGKEAEELQALPALEELEEEEleELLAALGLPPDLSPEELLELLDRIE-ELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1889 DGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER--LMNQLAELNGSIGNYCQDVTDAQIKNELLESEM 1966
Cdd:COG4717    360 EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELeeLEEQLEELLGELEELLEALDEEELEEELEELEE 439

                          410       420       430
                   ....*....|....*....|....*....|
gi 1622909118 1967 KnlkkcVSELEEEKQQLVKEKTKVESEIRK 1996
Cdd:COG4717    440 E-----LEELEEELEELREELAELEAELEQ 464
PTZ00121 PTZ00121
MAEBL; Provisional
 710-1250 1.44e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 47.83  E-value: 1.44e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  710 KAQEIYEKNLDEKAKEISNLNQLIEEFKK----NADNNSSAFTALSEERDQLLAQVKELSVVTELRA--QVRQLEMNLAE 783
Cdd:PTZ00121  1231 KAEEAKKDAEEAKKAEEERNNEEIRKFEEarmaHFARRQAAIKAEEARKADELKKAEEKKKADEAKKaeEKKKADEAKKK 1310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  784 AERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEG-AERV 862
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKkAEEK 1390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  863 R---HISSKVEEL---SQALSQKELEIAKMDQLL--LEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGV 934
Cdd:PTZ00121  1391 KkadEAKKKAEEDkkkADELKKAAAAKKKADEAKkkAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  935 EIKTLKEQLNLLSRAEEAKKeQVEEDNEVVSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKrklqAALINRKELL 1014
Cdd:PTZ00121  1471 KADEAKKKAEEAKKADEAKK-KAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKK----ADEAKKAEEK 1545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1015 QRVSRLEEELANLKDQSKKEIplsESERGEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKMAA 1094
Cdd:PTZ00121  1546 KKADELKKAEELKKAEEKKKA---EEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1095 E-----EQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETvvispPGTDSGEHWKPE 1169
Cdd:PTZ00121  1623 EelkkaEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEE-----DEKKAAEALKKE 1697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1170 LEEKilaleKEKEQLQKKLQEALTSRKAiLKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVR 1249
Cdd:PTZ00121  1698 AEEA-----KKAEELKKKEAEEKKKAEE-LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771


                   .
gi 1622909118 1250 E 1250
Cdd:PTZ00121  1772 E 1772
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1397-2329 1.53e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1397 ELQPELDELQKlISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKP 1476
Cdd:pfam01576    6 EMQAKEEELQK-VKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRL 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1477 EEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLAD----VESHVSAQNKEKDRVLGRLAll 1552
Cdd:pfam01576   85 EEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEdillLEDQNSKLSKERKLLEERIS-- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1553 qeERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYEN 1632
Cdd:pfam01576  163 --EFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAK 240

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1633 VSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKFAKSKQQKILELEEEND------R 1706
Cdd:pfam01576  241 KEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDttaaqqE 320

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1707 LRAEVHPAGGTAKECMETLLSSN---------------ASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQL 1771
Cdd:pfam01576  321 LRSKREQEVTELKKALEEETRSHeaqlqemrqkhtqalEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAK 400

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1772 ESNVSKQANLEA-----TEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNY 1846
Cdd:pfam01576  401 QDSEHKRKKLEGqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEE 480

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1847 LQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKETA--- 1923
Cdd:pfam01576  481 TRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALtqq 560

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1924 EEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQ 2003
Cdd:pfam01576  561 LEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALS 640

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2004 GAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQA 2083
Cdd:pfam01576  641 LARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEV 720

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2084 ELASFKVLLD------DTQSE--------AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQA---EEKHLKEK 2146
Cdd:pfam01576  721 NMQALKAQFErdlqarDEQGEekrrqlvkQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAAnkgREEAVKQL 800

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2147 KNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKW------- 2219
Cdd:pfam01576  801 KKLQAQMKDLQRELEEARASRDEILAQSKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELADEIASGasgksal 880

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2220 ---ERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQtevqlqqkvcdTLQGENKE 2296
Cdd:pfam01576  881 qdeKRRLEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERSTSQKSESARQ-----------QLERQNKE 949

                          970       980       990
                   ....*....|....*....|....*....|....
gi 1622909118 2297 LLSQLEETRHLYHNSQ-NELAKLESELNILKDQL 2329
Cdd:pfam01576  950 LKAKLQEMEGTVKSKFkSSIAALEAKIAQLEEQL 983
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1852-2183 1.76e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 47.43  E-value: 1.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1852 QLKERIAGLEEEKQKNKEFSQTLENERNALLSQIST-KDGELKLLQEEVSKMNLLNQQIQEELSRVTKlketaEEEKDDL 1930
Cdd:pfam17380  288 QQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKaRQAEMDRQAAIYAEQERMAMERERELERIRQ-----EERKREL 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1931 EERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgaqkepg 2010
Cdd:pfam17380  363 ERIRQEEIAMEISRMRELERLQMERQQKNERVRQELEAARK-VKILEEERQRKIQQQKVEMEQIRAEQEEARQ------- 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2011 nkshaKELQELLKEKQQEVKQLQKDCIRYQEKISALErtvkalefvqtesQKDLEITKENLAQAVEHRKKAQAELASFKV 2090
Cdd:pfam17380  435 -----REVRRLEEERAREMERVRLEEQERQQQVERLR-------------QQEEERKRKKLELEKEKRDRKRAEEQRRKI 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2091 LLDDTQSEAARVLADNLK---LKKELQSNKESVKSQMKQKDEDLERRleqaEEKHLKEKKNMQEKLDALRREKVHLEETI 2167
Cdd:pfam17380  497 LEKELEERKQAMIEEERKrklLEKEMEERQKAIYEEERRREAEEERR----KQQEMEERRRIQEQMRKATEERSRLEAME 572

                          330
                   ....*....|....*.
gi 1622909118 2168 GEIQVTLNKKDKEIQQ 2183
Cdd:pfam17380  573 REREMMRQIVESEKAR 588
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1086-1527 1.80e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.45  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1086 KDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDsgeh 1165
Cdd:COG4717     74 KELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLE---- 149

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1166 wkpELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQ 1245
Cdd:COG4717    150 ---ELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1246 IQVRESIDGKLPSPDQQ--EWCSPTPGLEEPLFKATEQHHTQPVLESNLCP----------------DWPSHSEDASALQ 1307
Cdd:COG4717    227 EELEQLENELEAAALEErlKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgllallflllAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1308 GGTSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESsql 1387
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVED--- 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1388 qiagLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEdlikalHTQLEMQAKEHDERIKQLQV 1467
Cdd:COG4717    384 ----EEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEE------LEELEEELEELEEELEELRE 453

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1468 ELCEMKQKPEEIEEESRAkQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKS 1527
Cdd:COG4717    454 ELAELEAELEQLEEDGEL-AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
mukB PRK04863
chromosome partition protein MukB;
2703-3026 1.99e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.26  E-value: 1.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2703 RNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDH------------------------- 2757
Cdd:PRK04863   292 RRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQqekieryqadleeleerleeqnevv 371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2758 --ANEELDELKRKYDASLKELAQLKEQ-----QGLLNRERHAL-----------LSETTFSMDLPEENSLSYLEKLNQQL 2819
Cdd:PRK04863   372 eeADEQQEENEARAEAAEEEVDELKSQladyqQALDVQQTRAIqyqqavqalerAKQLCGLPDLTADNAEDWLEEFQAKE 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2820 LSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQN-----ERDHLWNE-LEKFRKSEEgkQRSAAQPATSL-AEVQSLKKAM 2892
Cdd:PRK04863   452 QEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKiagevSRSEAWDVaRELLRRLRE--QRHLAEQLQQLrMRLSELEQRL 529

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2893 sSLQNDRDRLLKELKNLQQQYLQINQEITELR-PLKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSW-EI 2970
Cdd:PRK04863   530 -RQQQRAERLLAEFCKRLGKNLDDEDELEQLQeELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWlAA 608

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2971 HER--RMKEQYLMAISDKDQQVSHLQNLIRELRS-------SSSQAQPLKVQYQRQASPETSASP 3026
Cdd:PRK04863   609 QDAlaRLREQSGEEFEDSQDVTEYMQQLLEREREltverdeLAARKQALDEEIERLSQPGGSEDP 673
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2115-2793 2.41e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 47.14  E-value: 2.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2115 SNKESVKSQMKQKDEDLERRLEqaEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQ 2194
Cdd:pfam12128  207 EDDGVVPPKSRLNRQQVEHWIR--DIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQET 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2195 LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEEncsvlkDQLRQMSIHMEELKINISRLEhdkqiwes 2274
Cdd:pfam12128  285 SAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALED------QHGAFLDADIETAAADQEQLP-------- 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2275 KAQTEVQLQQKVCDTLQGENKELlSQLEETRHLYHNSQN--ELAKLESELNILKDQLTDLsnsLEKCKEQKENLEGIIRQ 2352
Cdd:pfam12128  351 SWQSELENLEERLKALTGKHQDV-TAKYNRRRSKIKEQNnrDIAGIKDKLAKIREARDRQ---LAVAEDDLQALESELRE 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2353 QeADIQNSKFSYEQLETDLQASrELTSRLHEEINMKEQKMisllsgKEEAIQVAIAELRQQHDKEIKELENLLSQEEEEN 2432
Cdd:pfam12128  427 Q-LEAGKLEFNEEEYRLKSRLG-ELKLRLNQATATPELLL------QLENFDERIERAREEQEAANAEVERLQSELRQAR 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2433 IVLEEENKKAVDKTNQLMETLNAIkkeniqQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2512
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSAL------DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2513 NNKLKEEIRGLRSHMDDLN-SENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEAN 2591
Cdd:pfam12128  573 SVGGELNLYGVKLDLKRIDvPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNAR 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2592 EDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKE-------EELQRLSALLSSSQKRIT 2664
Cdd:pfam12128  653 LDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEqkreartEKQAYWQVVEGALDAQLA 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2665 ELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDagimrnetetaEERVAELARDLVEMEQKLLMVTKENKDLTaQIQSF 2744
Cdd:pfam12128  733 LLKAAIAARRSGAKAELKALETWYKRDLASLGVD-----------PDVIAKLKREIRTLERKIERIAVRRQEVL-RYFDW 800

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 2745 GRSMSSLQnsRDHANEELDELKRKYDASLKELAQLKEQQGL----LNRERHAL 2793
Cdd:pfam12128  801 YQETWLQR--RPRLATQLSNIERAISELQQQLARLIADTKLrrakLEMERKAS 851
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 717-1254 2.64e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 2.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  717 KNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELsvvtelRAQVRQLEMNLAEAERQRRFDYESQT 796
Cdd:TIGR04523  117 EQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDL------KKQKEELENELNLLEKEKLNIQKNID 190

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  797 AHHNLLTEQIHSLSIeAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQAL 876
Cdd:TIGR04523  191 KIKNKLLKLELLLSN-LKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQL 269

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  877 SQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKF---------------SLGVEIKTLKE 941
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNKELKSELKNQEKKLeeiqnqisqnnkiisQLNEQISQLKK 349

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  942 QLNLLSRAEEAKKEQVEEDNEVVSGLK---QNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVS 1018
Cdd:TIGR04523  350 ELTNSESENSEKQRELEEKQNEIEKLKkenQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIE 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1019 RLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIEiSLKQTISEKEVELEHIRKDLEEKMAAEEQL 1098
Cdd:TIGR04523  430 RLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSIN-KIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1099 QALVKEMNQTLQDKTNQIDLLQAEISE-NQVIIQKLTTSNTDASDGDSVALVKEtvvisppgTDSGEHWKPELEEKILAL 1177
Cdd:TIGR04523  509 EEKVKDLTKKISSLKEKIEKLESEKKEkESKISDLEDELNKDDFELKKENLEKE--------IDEKNKEIEELKQTQKSL 580

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1178 EKEKEQLQKKLQEALTSRKAILKKAQEKERhLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1254
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEEKEK-KISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKE 656
PTZ00440 PTZ00440
reticulocyte binding protein 2-like protein; Provisional
 1907-2468 2.93e-04

reticulocyte binding protein 2-like protein; Provisional


Pssm-ID: 240419 [Multi-domain]  Cd Length: 2722  Bit Score: 47.13  E-value: 2.93e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1907 QQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSElEEEKQQLVKE 1986
Cdd:PTZ00440   479 EKDSMDSKEKKESSDSNYQEKVDELLQIINSIKEKNNIVNNNFKNIEDYYITIEGLKNEIEGLIELIKY-YLQSIETLIK 557

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1987 KTKVESEIRKEYLEKIQGAQkepGNKSHAKELQELLKEKQ---QEVKQLQKDCIRYQEKISALERTVKAL--EFVQTESQ 2061
Cdd:PTZ00440   558 DEKLKRSMKNDIKNKIKYIE---ENVDHIKDIISLNDEIDniiQQIEELINEALFNKEKFINEKNDLQEKvkYILNKFYK 634

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2062 KDLEITKENLAQAVEHRKKAQAELAS---FKVLLDDTQSEAARVL---ADNL-----KLKKELQSNKESVKSQMKQKDED 2130
Cdd:PTZ00440   635 GDLQELLDELSHFLDDHKYLYHEAKSkedLQTLLNTSKNEYEKLEfmkSDNIdniikNLKKELQNLLSLKENIIKKQLNN 714

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2131 LERRLEQAEEKHLKEKKNMQEKLDALRREKVHLE---ETIGEIQ----VTLNKKDKEI-------QQVQENLDSTVAQLA 2196
Cdd:PTZ00440   715 IEQDISNSLNQYTIKYNDLKSSIEEYKEEEEKLEvykHQIINRKnefiLHLYENDKDLpdgkntyEEFLQYKDTILNKEN 794

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2197 AFTKSMSSLQDDRDRVIDEAKKWE-----------------RKFSDAIQTKEEEIRLKE------ENCSVLKDQLRQMSI 2253
Cdd:PTZ00440   795 KISNDINILKENKKNNQDLLNSYNiliqkleahtekndeelKQLLQKFPTEDENLNLKElekefnENNQIVDNIIKDIEN 874

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2254 H------MEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESEL-NILK 2326
Cdd:PTZ00440   875 MnkniniIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQHMKIINTDNIIQKNEKLNLLNNLNKEKEKIEKQLsDTKI 954

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2327 DQL-TDLSNSLEKCKEQKENLEGI-------IRQQEADIQNSKFSYEQLETDLQAsreLTSRLHEEINMKEQKMISLLSG 2398
Cdd:PTZ00440   955 NNLkMQIEKTLEYYDKSKENINGNdgthlekLDKEKDEWEHFKSEIDKLNVNYNI---LNKKIDDLIKKQHDDIIELIDK 1031

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2399 KEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLD 2468
Cdd:PTZ00440  1032 LIKEKGKEIEEKVDQYISLLEKMKTKLSSFHFNIDIKKYKNPKIKEEIKLLEEKVEALLKKIDENKNKLI 1101
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1948-2632 2.96e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 46.65  E-value: 2.96e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1948 YCQDVTDAQIK----NELLESEMKNLKKCVSELEEEKQQLVKEKTKVeSEIRKEYLEKIQGAQKEPGNKSH----AKELQ 2019
Cdd:pfam15921   83 YSHQVKDLQRRlnesNELHEKQKFYLRQSVIDLQTKLQEMQMERDAM-ADIRRRESQSQEDLRNQLQNTVHeleaAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2020 E-LLKEKQQEVKQLQKDCIRYQEKISALERTVkaLEFVQTESQKdleITKENLAQAVEHRKKAQAelasFKVLLDDTQSE 2098
Cdd:pfam15921  162 EdMLEDSNTQIEQLRKMMLSHEGVLQEIRSIL--VDFEEASGKK---IYEHDSMSTMHFRSLGSA----ISKILRELDTE 232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2099 AARVLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKD 2178
Cdd:pfam15921  233 ISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQN 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2179 KEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDeaKKWERKFSDAIQTKEEEIRLKEENCSvLKDQLRQM--SIHME 2256
Cdd:pfam15921  313 SMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELE--KQLVLANSELTEARTERDQFSQESGN-LDDQLQKLlaDLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2257 ELKINISRlEHDKQIWESKAQTEVQLQ-------------QKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESeln 2323
Cdd:pfam15921  390 EKELSLEK-EQNKRLWDRDTGNSITIDhlrrelddrnmevQRLEALLKAMKSECQGQMERQMAAIQGKNESLEKVSS--- 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2324 iLKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKE--- 2400
Cdd:pfam15921  466 -LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDhlr 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2401 ------EAIQVAIAE-------LRQQhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQL 2467
Cdd:pfam15921  545 nvqtecEALKLQMAEkdkvieiLRQQ----IENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKI 620

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2468 DSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQE---AAAENNKLKEEI----RGLRSHMDDLNSENAKLDAE 2540
Cdd:pfam15921  621 RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEvktSRNELNSLSEDYevlkRNFRNKSEEMETTTNKLKMQ 700

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2541 LIQYREDLNQV------ISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIES 2614
Cdd:pfam15921  701 LKSAQSELEQTrntlksMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELST 780

                          730
                   ....*....|....*...
gi 1622909118 2615 LKVSVSQLTRQVTALQEE 2632
Cdd:pfam15921  781 VATEKNKMAGELEVLRSQ 798
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 2684-2942 3.07e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 3.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2684 IEDKLKKELKHLHhDAGIMRNE---TETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGR-SMSSLQNSRDHAN 2759
Cdd:PRK05771    14 LKSYKDEVLEALH-ELGVVHIEdlkEELSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKvSVKSLEELIKDVE 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2760 EELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYL---------EKLNQQLLSKDEQLLHLS 2830
Cdd:PRK05771    93 EELEKIEKEIKELEEEISELENEIKELEQEIERLEPWGNFDLDLSLLLGFKYVsvfvgtvpeDKLEELKLESDVENVEYI 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2831 SQLEDSYNQVQSFSKAMASLQNE--RDHlwnELEKFRKSEEGkqrsaaqpaTSLAEVQSLKKAMSSLQNDRDRLLKELKN 2908
Cdd:PRK05771   173 STDKGYVYVVVVVLKELSDEVEEelKKL---GFERLELEEEG---------TPSELIREIKEELEEIEKERESLLEELKE 240

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909118 2909 LQQQYLQINQEITELRPLKAQLQEYQDKT----KTFQI 2942
Cdd:PRK05771   241 LAKKYLEELLALYEYLEIELERAEALSKFlktdKTFAI 278
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 801-1032 3.20e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  801 LLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKE 880
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  881 LEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEI----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAE 950
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  951 EAKKEQVEEDNEVVSGLKQNYDEMspaglisKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQ 1030
Cdd:COG4942    170 EAERAELEALLAELEEERAALEAL-------KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242


                   ..
gi 1622909118 1031 SK 1032
Cdd:COG4942    243 TP 244
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1774-2180 3.43e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 46.43  E-value: 3.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1774 NVSKQANLEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSSHDEINNYLQQIDQ 1852
Cdd:PLN02939    41 GFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELpQKSTSSDDDHNRASMQRDEAIAAIDNEQQTNSK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1853 LKERIAGLEEEkqknkEFSQTLEN-ERNALLsqistkdgelkllqeevskMNLLNQQIQEELSRVTKLKETAEEEKDDLE 1931
Cdd:PLN02939   121 DGEQLSDFQLE-----DLVGMIQNaEKNILL-------------------LNQARLQALEDLEKILTEKEALQGKINILE 176

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1932 ERLMNQLAELNGSignycqdvTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEkiqgaqkepgn 2011
Cdd:PLN02939   177 MRLSETDARIKLA--------AQEKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENML----------- 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2012 kshAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDL----EITKENLAQAVEhrkkaqaelaS 2087
Cdd:PLN02939   238 ---LKDDIQFLKAELIEVAETEERVFKLEKERSLLDASLRELESKFIVAQEDVsklsPLQYDCWWEKVE----------N 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2088 FKVLLDDTQSE---AARVLADNLKLKKELQSNKESVKSQMKQKD-----EDLERRLEQAEEKHLKEKKNMQEKLDAlrre 2159
Cdd:PLN02939   305 LQDLLDRATNQvekAALVLDQNQDLRDKVDKLEASLKEANVSKFssykvELLQQKLKLLEERLQASDHEIHSYIQL---- 380

                          410       420
                   ....*....|....*....|.
gi 1622909118 2160 kvhLEETIGEIQVTLNKKDKE 2180
Cdd:PLN02939   381 ---YQESIKEFQDTLSKLKEE 398
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 668-1244 4.03e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 46.58  E-value: 4.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  668 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAqeIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAF 747
Cdd:TIGR01612 1119 DIKNLDQKIDHHIKALEEIKKKSENYIDEIKAQINDLEDVADKA--ISNDDPEEIEKKIENIVTKIDKKKNIYDEIKKLL 1196

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  748 TALSE-ERDQL-LAQVKELSVVTELRAQVRQLEmNLAEAERQRRFDYESQTAHHNLLTE------QIHSLSIEAKSKDVK 819
Cdd:TIGR01612 1197 NEIAEiEKDKTsLEEVKGINLSYGKNLGKLFLE-KIDEEKKKSEHMIKAMEAYIEDLDEikekspEIENEMGIEMDIKAE 1275

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  820 IEVLQNELDDVQLQFSEQSTLIRSLqSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVET 899
Cdd:TIGR01612 1276 METFNISHDDDKDHHIISKKHDENI-SDIREKSLKIIEDFSEESDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNI 1354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  900 LQ-QTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLlsraeEAKKEQVEE--DNEVVSGLKQNYDEMSP 976
Cdd:TIGR01612 1355 LKlNKIKKIIDEVKEYTKEIEENNKNIKDELDKSEKLIKKIKDDINL-----EECKSKIEStlDDKDIDECIKKIKELKN 1429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  977 AGLISKEELQHEFDLLKKENEQrkrklqaALINRKELLQRVSRLEEELANLKDQSKKEIPLSesergeVEEDKENKEYSE 1056
Cdd:TIGR01612 1430 HILSEESNIDTYFKNADENNEN-------VLLLFKNIEMADNKSQHILKIKKDNATNDHDFN------INELKEHIDKSK 1496

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1057 KCVTskcqEIEISLKQTISEKEVeLEHIRKDLEEKMAAEEQLqALVKEMNQTLQDKTNQID---------LLQAEISE-- 1125
Cdd:TIGR01612 1497 GCKD----EADKNAKAIEKNKEL-FEQYKKDVTELLNKYSAL-AIKNKFAKTKKDSEIIIKeikdahkkfILEAEKSEqk 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1126 -NQVIIQKLTTSNTDASDGDS-VALVKETVVISPpgtdsgehwkpeLEEKILALEkekeQLQKKLQEALTSRKAILKKAQ 1203
Cdd:TIGR01612 1571 iKEIKKEKFRIEDDAAKNDKSnKAAIDIQLSLEN------------FENKFLKIS----DIKKKINDCLKETESIEKKIS 1634

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909118 1204 EKERHLRE-ELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1244
Cdd:TIGR01612 1635 SFSIDSQDtELKENGDNLNSLQEFLESLKDQKKNIEDKKKEL 1676
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1908-2541 4.06e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 46.37  E-value: 4.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1908 QIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKcvSELEEEKQQLVKEK 1987
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLD--ADIETAAADQEQLP 350

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1988 TkVESEIrkEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQL----QKDCIRYQEKISALERTVKALEFVQTESQKD 2063
Cdd:pfam12128  351 S-WQSEL--ENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIagikDKLAKIREARDRQLAVAEDDLQALESELREQ 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2064 LEITKENLAQAVEHRKKAQAELasfKVLLDDTQSEaarvladnlklkKELQSNKESVKSQMKQKDEDLERR---LEQAEE 2140
Cdd:pfam12128  428 LEAGKLEFNEEEYRLKSRLGEL---KLRLNQATAT------------PELLLQLENFDERIERAREEQEAAnaeVERLQS 492

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2141 KHLKEKKNMQEKLDALRREKVHLEETIGeiqvtlnkkdkEIQQVQENLDSTVAQLAAFTKSMSSL-QDDRDRVIDEAKKW 2219
Cdd:pfam12128  493 ELRQARKRRDQASEALRQASRRLEERQS-----------ALDELELQLFPQAGTLLHFLRKEAPDwEQSIGKVISPELLH 561

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2220 ErkfSDAIQTKEEEIRLKEENCSVLKDQLRQMSI-----HMEELKINISRLEHDKQiwesKAQTEVQLQQKVCDTLQGEN 2294
Cdd:pfam12128  562 R---TDLDPEVWDGSVGGELNLYGVKLDLKRIDVpewaaSEEELRERLDKAEEALQ----SAREKQAAAEEQLVQANGEL 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2295 KELLSQLEETRHLYHNSQNELAKLESELNILKDQLTD-LSNSLEKCKEQKENLEGIIRQQEADIQNSkfsyeqletdLQA 2373
Cdd:pfam12128  635 EKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKaLAERKDSANERLNSLEAQLKQLDKKHQAW----------LEE 704

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2374 SRELTSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETL 2453
Cdd:pfam12128  705 QKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKI 784

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2454 NAIKKeNIQQKAQLDSFVKSMSSLQNDRDRIvgdyqQLEERHLSVILEKDQL---IQEAAAENNKLKEEIRGLRSHMDDL 2530
Cdd:pfam12128  785 ERIAV-RRQEVLRYFDWYQETWLQRRPRLAT-----QLSNIERAISELQQQLarlIADTKLRRAKLEMERKASEKQQVRL 858

                          650
                   ....*....|.
gi 1622909118 2531 NSENAKLDAEL 2541
Cdd:pfam12128  859 SENLRGLRCEM 869
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1995-2188 4.17e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.91  E-value: 4.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1995 RKEYLEKIQGaQKEPGNKSHAKELQELLKEKQQEVKQLQKDciryQEKISALERTVKALEFVQTESQKDLEITK--ENLA 2072
Cdd:COG4717     54 EADELFKPQG-RKPELNLKELKELEEELKEAEEKEEEYAEL----QEELEELEEELEELEAELEELREELEKLEklLQLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2073 QAVEHRKKAQAELASFKVLLDDTQSEAARVladnlklkKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEK 2152
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190
                   ....*....|....*....|....*....|....*.
gi 1622909118 2153 LDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENL 2188
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENEL 236
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2274-2483 4.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2274 SKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQ 2353
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2354 EADIQ-NSKFSYEQL----ETDLQASRELtsRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHdKEIKELENLLSQE 2428
Cdd:COG4942    110 LRALYrLGRQPPLALllspEDFLDAVRRL--QYLKYLAPARREQAEELRADLAELAALRAELEAER-AELEALLAELEEE 186

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2429 EEENIVLEEENKKAVDKTNQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDR 2483
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK12704 PRK12704
phosphodiesterase; Provisional
 2077-2239 5.40e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.54  E-value: 5.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2077 HRKKAQAELASFKVLLDDTQsEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR--LEQAEEKHLKEKKNMQEKLD 2154
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2155 ALRREKVHLEETIGEiqvtLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDD--RDRVIDEAKKwERKFSDAIQTKEE 2232
Cdd:PRK12704   104 LLEKREEELEKKEKE----LEQKQQELEKKEEELEELIEEQLQELERISGLTAEeaKEILLEKVEE-EARHEAAVLIKEI 178


                   ....*..
gi 1622909118 2233 EIRLKEE 2239
Cdd:PRK12704   179 EEEAKEE 185
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1311-1511 6.52e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.39  E-value: 6.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1311 SVAQIKAQLKEIETEKEKLELKISS--TTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQ 1388
Cdd:COG3206    176 ALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1389 IAGLEHLRELQPELDELQKLISEKEEdvsyLSGQLREKEAALTKIQTEIIEQEDLIKA----LHTQLEMQAKEHDERIKQ 1464
Cdd:COG3206    256 LPELLQSPVIQQLRAQLAELEAELAE----LSARYTPNHPDVIALRAQIAALRAQLQQeaqrILASLEAELEALQAREAS 331

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1622909118 1465 LQVELCEMKQKPEEIEEESRAKQQIQRKLQAA------LISRKEALKENKSLQ 1511
Cdd:COG3206    332 LQAQLAQLEARLAELPELEAELRRLEREVEVArelyesLLQRLEEARLAEALT 384
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-459 6.62e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 6.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  245 LLQLVTQADVETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLR---NTVETE 321
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  322 REESKILLEKMELEVAER---------------KLSFHNLQEEMR--HLLEQLEQAGQAQAE-LESRYSALEQKhKAEME 383
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRrlQYLKYLAPARREQAEeLRADLAELAAL-RAELE 170

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118  384 EKTSHILSLQKTGQELQSACDALKDQNSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQ 459
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
46 PHA02562
endonuclease subunit; Provisional
 2546-2782 6.99e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 6.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2546 EDL--NQVISIKDSQQKQLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRD----LSKEIESLKVSV 2619
Cdd:PHA02562   157 EDLldISVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKTIKAEI 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2620 SQLTRQVTALQEEGtlGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVC------------VQKEAAKKVGEIEDK 2687
Cdd:PHA02562   237 EELTDELLNLVMDI--EDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCptctqqisegpdRITKIKDKLKELQHS 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2688 LKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIQsfgrsmsSLQNSRDHANEELDELKR 2767
Cdd:PHA02562   315 LEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEELAKLQD 386

                          250
                   ....*....|....*
gi 1622909118 2768 KYDASLKELAQLKEQ 2782
Cdd:PHA02562   387 ELDKIVKTKSELVKE 401
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2467-3070 7.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2467 LDSFVKSM----SSLQNDRDRIVGDYQQLEERHLSVILEKDQL-----IQEAAAENNKLKEEIRGLRSHMDDLNSENAKL 2537
Cdd:COG4913    209 LDDFVREYmleePDTFEAADALVEHFDDLERAHEALEDAREQIellepIRELAERYAAARERLAELEYLRAALRLWFAQR 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2538 DAELIQYREDLNQvisikdsQQKQLLEAQLQQNKELKNKyAKLEEKLKESEEANEDLQRSsNALQEEKRDLSKEIESLKV 2617
Cdd:COG4913    289 RLELLEAELEELR-------AELARLEAELERLEARLDA-LREELDELEAQIRGNGGDRL-EQLEREIERLERELEERER 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2618 SVSQLTRQVTALQEE--GTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDkLKKELKHL 2695
Cdd:COG4913    360 RRARLEALLAALGLPlpASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIAS-LERRKSNI 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2696 HHDAGIMRNETETA----EER---VAEL---------------------ARDLVEMEQKLLMVTK--ENKDLTAQIQSFG 2745
Cdd:COG4913    439 PARLLALRDALAEAlgldEAElpfVGELievrpeeerwrgaiervlggfALTLLVPPEHYAAALRwvNRLHLRGRLVYER 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2746 --RSMSSLQNSRDHAN---EELD------------ELKRKYD----ASLKELAQLKE---QQGLL--NRERHALlsettf 2799
Cdd:COG4913    519 vrTGLPDPERPRLDPDslaGKLDfkphpfrawleaELGRRFDyvcvDSPEELRRHPRaitRAGQVkgNGTRHEK------ 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2800 sMDLPEENSLSYLEKLN-QQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQnERDHLWNELEKFRKSE---------- 2868
Cdd:COG4913    593 -DDRRRIRSRYVLGFDNrAKLAALEAELAELEEELAEAEERLEALEAELDALQ-ERREALQRLAEYSWDEidvasaerei 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2869 EGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELR 2948
Cdd:COG4913    671 AELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAE---EELDELQDRLEAAEDLARLEL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2949 QENLswQHELHQLRMEKssweiHERRMKEQYLMAISDKDQQVSHLQNLIRELRSsssqaqplkvQYQRQASPETSASPDG 3028
Cdd:COG4913    748 RALL--EERFAAALGDA-----VERELRENLEERIDALRARLNRAEEELERAMR----------AFNREWPAETADLDAD 810

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....
gi 1622909118 3029 SQNLIYETELLRNQLNDSLKEIHQK--ELRIQQLNSKFSQLLEE 3070
Cdd:COG4913    811 LESLPEYLALLDRLEEDGLPEYEERfkELLNENSIEFVADLLSK 854
PLN02939 PLN02939
transferase, transferring glycosyl groups
 1379-1742 8.19e-04

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 45.28  E-value: 8.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1379 QQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYL---SGQLREKEAALTKIQTEIIEQEDLiKALHTQLEMQA 1455
Cdd:PLN02939    39 RRGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSlrtVMELPQKSTSSDDDHNRASMQRDE-AIAAIDNEQQT 117

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1456 KEHD-ERIKQLQVE-LCEMKQKPEE-IEEESRAKQQIQRKLQAALiSRKEAL-KENKSLQEELSLARDTIEHLTKSLADV 1531
Cdd:PLN02939   118 NSKDgEQLSDFQLEdLVGMIQNAEKnILLLNQARLQALEDLEKIL-TEKEALqGKINILEMRLSETDARIKLAAQEKIHV 196

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1532 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKE---KLVKEIESLKSS---- 1604
Cdd:PLN02939   197 EILEEQLEKLRNELLIRGATEGLCVHSLSKELDVLKEENMLLKDDIQFLKAELIEVAETEErvfKLEKERSLLDASlrel 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1605 --KIAESSEWQEKHKELQkeYEILLQSYENVSNEAERIQHVVE---AVRQEKQELYGKLRSTEANKKETekqlqeaekem 1679
Cdd:PLN02939   277 esKFIVAQEDVSKLSPLQ--YDCWWEKVENLQDLLDRATNQVEkaaLVLDQNQDLRDKVDKLEASLKEA----------- 343

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1680 eemkeKMRKFAKSK----QQKILELEEENDRLRAEVHPAGGTAKECMETLLSSNASMKEEVERVKME 1742
Cdd:PLN02939   344 -----NVSKFSSYKvellQQKLKLLEERLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKRSLE 405
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2523-2725 8.27e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 8.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2523 LRSHMDDLNSENAKLDAELIQYREDLNQvisikdsqqkqlLEAQLQQNKElKNKYAKLEEKLKESEEANEDLQRSSNALQ 2602
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELEE------------AEAALEEFRQ-KNGLVDLSEEAKLLLQQLSELESQLAEAR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2603 EEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVG 2682
Cdd:COG3206    233 AELAEAEARLAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQ 312

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|...
gi 1622909118 2683 EIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQ 2725
Cdd:COG3206    313 RILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRR 355
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2825-3097 8.32e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.31  E-value: 8.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2825 QLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKS--EEGKQRSAAQpatslAEVQSLKKAMSSLQNDRDRL 2902
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLEleELELELEEAQ-----AEEYELLAELARLEQDIARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2903 LKELKNLQQQYLQINQEITELRP----LKAQLQEYQDKTKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQ 2978
Cdd:COG1196    308 EERRRELEERLEELEEELAELEEeleeLEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2979 YLMAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQASPETSASPdgsqnliyETELLRNQLNDSLKEIHQKELRIQ 3058
Cdd:COG1196    388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE--------EEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1622909118 3059 QLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLN 3097
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2293-2513 8.89e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 8.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2293 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQ 2372
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2373 ASRE-LTSRLHEEINMKEQKMISLLSGKEEAIQVA-----IAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKT 2446
Cdd:COG4942    101 AQKEeLAELLRALYRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2447 NQLMETLNAIKKENIQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAEN 2513
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1318-1995 9.49e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.04  E-value: 9.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1318 QLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQInkQGLEIESLKTASHEAEVRAE----SLQQKLESSQLQIAGLE 1393
Cdd:TIGR00606  427 QADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKEL--QQLEGSSDRILELDQELRKAerelSKAEKNSLTETLKKEVK 504

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1394 HLRELQPELDELQKLISEKEEDVSYLSGQLREKEAaLTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMK 1473
Cdd:TIGR00606  505 SLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEM-LTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKS 583

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1474 QKPEEIEEESRakqQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSlADVESHVSAQNKEKDRVLGRLALLQ 1553
Cdd:TIGR00606  584 KEINQTRDRLA---KLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLA 659

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1554 EERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEdkekLVKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSYENV 1633
Cdd:TIGR00606  660 GATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGR 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1634 SNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLqEAEKEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHP 1713
Cdd:TIGR00606  736 QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLL-GTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAK 814

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1714 AGGTakecmeTLLSSNASMKEEVERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQLES----NVSKQANLEATEKHDN 1789
Cdd:TIGR00606  815 LQGS------DLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNElkseKLQIGTNLQRRQQFEE 888

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1790 QMNVTEEATQSIPGETED-QDSLSMSTRPACSESVPSENSANPAVSEDVSSHDEINNYLQQIDQLKERIAGLEEEKQKNK 1868
Cdd:TIGR00606  889 QLVELSTEVQSLIREIKDaKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGK 968

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1869 E-FSQTLENERNALLSQISTKDGELKLLQEEVSKM--NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGsi 1945
Cdd:TIGR00606  969 DdYLKQKETELNTVNAQLEECEKHQEKINEDMRLMrqDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMGQ-- 1046

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1946 gnycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIR 1995
Cdd:TIGR00606 1047 ----MQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
PRK12704 PRK12704
phosphodiesterase; Provisional
 1665-1808 9.57e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.77  E-value: 9.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1665 KKETEKQLQEAEKEMEEMKEKMRKFAKS-KQQKILELEEENDRLRAEVHpaggtaKEcmetLLSSNASMKEEVERVKMEY 1743
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAiKKEALLEAKEEIHKLRNEFE------KE----LRERRNELQKLEKRLLQKE 95

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1744 ETLSKKFQSLMSEKDSLSEEVQDLKHQLESNVSKQANLEATEKHDNQ-----MNVT-EEATQSIPGETEDQ 1808
Cdd:PRK12704    96 ENLDRKLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQeleriSGLTaEEAKEILLEKVEEE 166
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 691-1023 1.08e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.06  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  691 QDELERLKSQILELELNFHKAQ---EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKEL-SV 766
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSqelSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELeAR 766

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  767 VTELRAQVRQLEMNLAEAERQRRFDYESQtahhnlLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQS 846
Cdd:TIGR02169  767 IEELEEDLHKLEEALNDLEARLSHSRIPE------IQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  847 QLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLN 926
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  927 EekfsLGVEIKTLKEQLNLLSRAEEAKKEQVEED---NEVVSGLKQNYDEMSPAGLISKEELQhEFDLLKKENEQRKRKL 1003
Cdd:TIGR02169  921 E----LKAKLEALEEELSEIEDPKGEDEEIPEEElslEDVQAELQRVEEEIRALEPVNMLAIQ-EYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|
gi 1622909118 1004 QAALINRKELLQRVSRLEEE 1023
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKK 1015
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
211-387 1.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  211 QTQAEQAAQLssmqQVVREKDARFEtQVRLHEDELLQLVTQADVETEmQQKLRVLQRKLEEHEESLVGRAQVVDLLQQEL 290
Cdd:COG4913    245 EDAREQIELL----EPIRELAERYA-AARERLAELEYLRAALRLWFA-QRRLELLEAELEELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  291 TAAEQR----------NQILSQQLQQIEAEHNTL-RNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQ 359
Cdd:COG4913    319 DALREEldeleaqirgNGGDRLEQLEREIERLEReLEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEE 398

                          170       180       190
                   ....*....|....*....|....*....|..
gi 1622909118  360 ----AGQAQAELESRYSALEQKHKAEMEEKTS 387
Cdd:COG4913    399 eleaLEEALAEAEAALRDLRRELRELEAEIAS 430
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1837-2074 1.14e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.44  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1837 VSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKmnlLNQQIQEelsRV 1916
Cdd:COG3883     12 AFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAE---AEAEIEE---RR 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1917 TKLKETAEEEKddLEERLMNQLAELNGSignycQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEirk 1996
Cdd:COG3883     86 EELGERARALY--RSGGSVSYLDVLLGS-----ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAK--- 155

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 1997 eyLEKIQGAQKEpgNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQA 2074
Cdd:COG3883    156 --LAELEALKAE--LEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAA 229
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1911-2573 1.14e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1911 EELSRVTKLKETAEEEKDDLE---------ERLMNQLAELNgsignYCQDVTD---AQIKNELLESEMKNLKKCVSELEE 1978
Cdd:COG4913    235 DDLERAHEALEDAREQIELLEpirelaeryAAARERLAELE-----YLRAALRlwfAQRRLELLEAELEELRAELARLEA 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1979 EKQQLVKEKTKVESEIR--KEYLEKIQGAQKEpgnkshakELQELLKEKQQEVKQLQKDCIRYQEKISALERTV----KA 2052
Cdd:COG4913    310 ELERLEARLDALREELDelEAQIRGNGGDRLE--------QLEREIERLERELEERERRRARLEALLAALGLPLpasaEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2053 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDL- 2131
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEAELp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2132 -----------ERRLEQAEEKHLKEKK-NM---QEKLDALRR--EKVHLEETIGEIQVTLNKKDKEIQQVQEN-----LD 2189
Cdd:COG4913    462 fvgelievrpeEERWRGAIERVLGGFAlTLlvpPEHYAAALRwvNRLHLRGRLVYERVRTGLPDPERPRLDPDslagkLD 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2190 S-----------------------TVAQLAAFTKSMSSL----QDDRDRVIDEAKKWERK----FS--DAIQTKEEEIRL 2236
Cdd:COG4913    542 FkphpfrawleaelgrrfdyvcvdSPEELRRHPRAITRAgqvkGNGTRHEKDDRRRIRSRyvlgFDnrAKLAALEAELAE 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2237 KEENCSVLKDQLRQMSIHMEELKINISRLEH-DKQIWESKAQTEVQLQqkvcdtlqgenkelLSQLEETRHLYHNSQNEL 2315
Cdd:COG4913    622 LEEELAEAEERLEALEAELDALQERREALQRlAEYSWDEIDVASAERE--------------IAELEAELERLDASSDDL 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2316 AKLESELNILKDQLTDLsnslekcKEQKENLEGIIRQQEADIqnskfsyEQLETDLQASREltsRLHEEINMKEQKMISL 2395
Cdd:COG4913    688 AALEEQLEELEAELEEL-------EEELDELKGEIGRLEKEL-------EQAEEELDELQD---RLEAAEDLARLELRAL 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2396 LSGK--EEAIQVAIAELRQQHDKEIKELENLLSQeeeenivleeenkkavdKTNQLMETLNAIKKENIQQKAQLDSFVKS 2473
Cdd:COG4913    751 LEERfaAALGDAVERELRENLEERIDALRARLNR-----------------AEEELERAMRAFNREWPAETADLDADLES 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2474 MSSLQNDRDRIVGD-----YQQLEErhlsviLEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSE--------------- 2533
Cdd:COG4913    814 LPEYLALLDRLEEDglpeyEERFKE------LLNENSIEFVADLLSKLRRAIREIKERIDPLNDSlkripfgpgrylrle 887

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 1622909118 2534 -NAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKEL 2573
Cdd:COG4913    888 aRPRPDPEVREFRQELRAVTSGASLFDEELSEARFAALKRL 928
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2174-2374 1.22e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2174 LNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKfsdaIQTKEEEIRLKEENCSVLKDQLRQMSI 2253
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAE----IDKLQAEIAEAEAEIEERREELGERAR 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2254 HMEELKINISRLEhdkQIWESKAQTEVQLQQKVCDTLQGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLS 2333
Cdd:COG3883     94 ALYRSGGSVSYLD---VLLGSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909118 2334 NSLEKCKEQKENLEGIIRQQEADIQNSKFSYEQLETDLQAS 2374
Cdd:COG3883    171 AELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAA 211
PRK01156 PRK01156
chromosome segregation protein; Provisional
 2291-2924 1.26e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.51  E-value: 1.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2291 QGENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLegiiRQQEADIQNSKFSYEQLETD 2370
Cdd:PRK01156   137 QGEMDSLISGDPAQRKKILDEILEINSLERNYDKLKDVIDMLRAEISNIDYLEEKL----KSSNLELENIKKQIADDEKS 212

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2371 LQASRELTSRLHEEINMKEQKMISL------LSGKEEAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVD 2444
Cdd:PRK01156   213 HSITLKEIERLSIEYNNAMDDYNNLksalneLSSLEDMKNRYESEIKTAESDLSMELEKNNYYKELEERHMKIINDPVYK 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2445 KTNQLMETLNAIKkeniqqkaQLDSFVKSMSSLQNDrdrivgdyqqleerhlsviLEKDQLIQEAAAENNKLKEEIRGLR 2524
Cdd:PRK01156   293 NRNYINDYFKYKN--------DIENKKQILSNIDAE-------------------INKYHAIIKKLSVLQKDYNDYIKKK 345

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2525 SHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQkqlleaqlQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEE 2604
Cdd:PRK01156   346 SRYDDLNNQILELEGYEMDYNSYLKSIESLKKKIE--------EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVK 417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2605 KRDLSKEIESLKVSVSQLTRqvtalqeegtlgiyhaqlkvKEEELQRLSALLSSSQKRI---TELEEELVcvqKEAAKKV 2681
Cdd:PRK01156   418 LQDISSKVSSLNQRIRALRE--------------------NLDELSRNMEMLNGQSVCPvcgTTLGEEKS---NHIINHY 474

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2682 GEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEmeqKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHANE- 2760
Cdd:PRK01156   475 NEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEIN---KSINEYNKIESARADLEDIKIKINELKDKHDKYEEi 551

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2761 -------ELDELKRKYDASLKELAQLKEQQGLLNRERHALLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQLLHLSSQL 2833
Cdd:PRK01156   552 knrykslKLEDLDSKRTSWLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2834 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQY 2913
Cdd:PRK01156   632 NNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRI 711

                          650
                   ....*....|.
gi 1622909118 2914 LQINQEITELR 2924
Cdd:PRK01156   712 NELSDRINDIN 722
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1313-1513 1.27e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1313 AQIKAQLKEIETEKEKLELKISSTTSELTKKSEEvfQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSqlqiaGL 1392
Cdd:COG4913    265 AAARERLAELEYLRAALRLWFAQRRLELLEAELE--ELRAELARLEAELERLEARLDALREELDELEAQIRGN-----GG 337

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1393 EHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEM 1472
Cdd:COG4913    338 DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1622909118 1473 KQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEE 1513
Cdd:COG4913    418 RRELRELEAEIASLERRKSNIPARLLALRDALAEALGLDEA 458
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 2600-2924 1.29e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.94  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2600 ALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVcVQKEAAK 2679
Cdd:COG3096    789 ELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHLAVAFAPDPEAELAALRQRRSELERELAQHRAQEQ-QLRQQLD 867

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2680 KVGEIEDKLKKELKHLHHDAgimrneTETAEERVAELARDLVEMEQKLLMVTKENKDLT------AQIQSFGRSMSSLQN 2753
Cdd:COG3096    868 QLKEQLQLLNKLLPQANLLA------DETLADRLEELREELDAAQEAQAFIQQHGKALAqleplvAVLQSDPEQFEQLQA 941

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2754 SRDHANEELDELKRKYDAsLKELAQlkeqqgllnrERHALLSETTFSMdLPEENSLSylEKLNQQLLSKDEQLLHLSSQL 2833
Cdd:COG3096    942 DYLQAKEQQRRLKQQIFA-LSEVVQ----------RRPHFSYEDAVGL-LGENSDLN--EKLRARLEQAEEARREAREQL 1007

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2834 EDSYNQVQSFSKAMASLQNERDHLWNELEKFRK--SEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLK------- 2904
Cdd:COG3096   1008 RQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQelEELGVQADAEAEERARIRRDELHEELSQNRSRRSQLEKqltrcea 1087

                          330       340
                   ....*....|....*....|
gi 1622909118 2905 ELKNLQQQYLQINQEITELR 2924
Cdd:COG3096   1088 EMDSLQKRLRKAERDYKQER 1107
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2568-3089 1.44e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2568 QQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLS-------KEIESLKVSVSQLTRQVTALQEEGTLGIYHA 2640
Cdd:pfam15921  138 QSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMlshegvlQEIRSILVDFEEASGKKIYEHDSMSTMHFRS 217

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2641 QLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIEDKLKKELKHLhhdagIMRNETE-TAEERVAELARD 2719
Cdd:pfam15921  218 LGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQHQDRIEQL-----ISEHEVEiTGLTEKASSARS 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2720 LVEMEQKLLMVTKENKdlTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELA------------------QLKE 2781
Cdd:pfam15921  293 QANSIQSQLEIIQEQA--RNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEkqlvlanseltearterdQFSQ 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2782 QQGLLNRERHALLSETTfsmdlPEENSLSYLEKLNQQLLSKDE----QLLHLSSQLEDSYNQVQ---------------S 2842
Cdd:pfam15921  371 ESGNLDDQLQKLLADLH-----KREKELSLEKEQNKRLWDRDTgnsiTIDHLRRELDDRNMEVQrleallkamksecqgQ 445

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2843 FSKAMASLQNERDHLWN--------------------ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSLQND 2898
Cdd:pfam15921  446 MERQMAAIQGKNESLEKvssltaqlestkemlrkvveELTAKKMTLESSERTVSDLTASLQEkeraIEATNAEITKLRSR 525

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2899 RDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyqdKTKTFQIMQEELRQ-ENLSWQH-------ELHQLRMEKsswEI 2970
Cdd:pfam15921  526 VDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE---KDKVIEILRQQIENmTQLVGQHgrtagamQVEKAQLEK---EI 599

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2971 HERRMKEQYLMAISDKDQQVshlqnlIRELRSSSSQAQPLKVQYQRQASPETSASPDGSQ---NLIYETELLRNQLNdSL 3047
Cdd:pfam15921  600 NDRRLELQEFKILKDKKDAK------IRELEARVSDLELEKVKLVNAGSERLRAVKDIKQerdQLLNEVKTSRNELN-SL 672

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1622909118 3048 KEihQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQ 3089
Cdd:pfam15921  673 SE--DYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
410-577 1.47e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  410 NSKLLQDKDEQAVQSAQTIEQLEDQLQQKSKEISQFLNRLplQQHETASQTCFPDVynegtqavteeNIASLQKRVVELE 489
Cdd:COG4913    608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERR--EALQRLAEYSWDEI-----------DVASAEREIAELE 674

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  490 NEKGALLLSSIELEELKAENEKLSSQITllEAQNRIGEADREVSEisiVDDANKRSSSTEESGQDVLENTFSQKHKELSV 569
Cdd:COG4913    675 AELERLDASSDDLAALEEQLEELEAELE--ELEEELDELKGEIGR---LEKELEQAEEELDELQDRLEAAEDLARLELRA 749


                   ....*...
gi 1622909118  570 LLLEMKEA 577
Cdd:COG4913    750 LLEERFAA 757
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2015-2539 1.71e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2015 AKELQELLKEKQQEVKQLQKDCIRYQEKISALERtvkalefvqtesqkdleiTKENLAQAVEHRKKAQAELASFKVLLDD 2094
Cdd:PRK02224   201 EKDLHERLNGLESELAELDEEIERYEEQREQARE------------------TRDEADEVLEEHEERREELETLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2095 TQSEAARVladnlklKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLK--EKKNMQEKLDALRREKVHLEETIGEIQV 2172
Cdd:PRK02224   263 LRETIAET-------EREREELAEEVRDLRERLEELEEERDDLLAEAGLDdaDAEAVEARREELEDRDEELRDRLEECRV 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2173 TLNKKDKEIQQVQENldstVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVLKDQLRQMS 2252
Cdd:PRK02224   336 AAQAHNEEAESLRED----ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAE 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2253 IHMEELKINISRLEhdkqiwESKAQTEVQLQQkVCDTLQgENKELLSQ---------LEETRHL--YHNSQNELAKLESE 2321
Cdd:PRK02224   412 DFLEELREERDELR------EREAELEATLRT-ARERVE-EAEALLEAgkcpecgqpVEGSPHVetIEEDRERVEELEAE 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2322 LNILKDQLTDLSNSL-------------EKCKEQKENLEGIIRQQEADIQNSKFSYEQ-------LETDLQASRELTSRL 2381
Cdd:PRK02224   484 LEDLEEEVEEVEERLeraedlveaedriERLEERREDLEELIAERRETIEEKRERAEElreraaeLEAEAEEKREAAAEA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2382 HEEINmKEQKMISLLSGKEEAIQVAIAELRQqhdkeIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLnaikKENI 2461
Cdd:PRK02224   564 EEEAE-EAREEVAELNSKLAELKERIESLER-----IRTLLAAIADAEDEIERLREKREALAELNDERRERL----AEKR 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2462 QQKAQLDSFVKS--MSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLkEEIRGLRSHMDDLNSENAKLDA 2539
Cdd:PRK02224   634 ERKRELEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENEL-EELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2401-2628 1.90e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2401 EAIQVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKKaVDKTNQLMETLNAIKKENIQQKAQLDsfvKSMSSLQND 2480
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARR-IRALEQELAALEAELAELEKEIAELR---AELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2481 RDRIVGDYQQLEERHLSVILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdaeliqyrEDLNQVISIKDSQQK 2560
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 2561 QLLEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTA 2628
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2293-2670 1.92e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2293 ENKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEKCKEQKENLEGIIRQQEADIQNSKFS--YEQLETD 2370
Cdd:COG4717     75 ELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPerLEELEER 154

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2371 LQASREL---TSRLHEEINMKEQKMISLLSGKEEAIQVAIAELRQQHDkEIKELENLLSQEEEENIVLEEENKKAVDKTN 2447
Cdd:COG4717    155 LEELRELeeeLEELEAELAELQEELEELLEQLSLATEEELQDLAEELE-ELQQRLAELEEELEEAQEELEELEEELEQLE 233

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2448 QLMETLNAIKKEN---------------IQQKAQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSVILEKDQLIQEAAAE 2512
Cdd:COG4717    234 NELEAAALEERLKearlllliaaallalLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPAL 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2513 NNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQLLEAQLQQNKElknkyakleEKLKESEEANE 2592
Cdd:COG4717    314 EELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIA---------ALLAEAGVEDE 384

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 2593 DLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQEEGTLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEEL 2670
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAEL 462
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 983-1633 1.98e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  983 EELQHEFDLLKKENEQRKRklqaalinrkellqrvsrLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKCVTSK 1062
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLES------------------AELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQ 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1063 CQEIEISLKQTISEKEVELEHIRKDLEekmAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTT------- 1135
Cdd:pfam12128  299 WKEKRDELNGELSAADAAVAKDRSELE---ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGkhqdvta 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1136 ------SNTDASDGDSVALVKETVVISPPGTDSG------------EHWKPELEEKILALEKEKEQLQKKLQEAltsrKA 1197
Cdd:pfam12128  376 kynrrrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaeddlqaleSELREQLEAGKLEFNEEEYRLKSRLGEL----KL 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1198 ILKKAQEKErHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQiQVRESIDGKLPSPDQ--QEWCSPTPGLEEPL 1275
Cdd:pfam12128  452 RLNQATATP-ELLLQLENFDERIERAREEQEAANAEVERLQSELRQAR-KRRDQASEALRQASRrlEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1276 FKateQHHTQPVLESNLCPDWPSH-----------------SEDASALQGGTSVAQIKAQLK------------EIETEK 1326
Cdd:pfam12128  530 FP---QAGTLLHFLRKEAPDWEQSigkvispellhrtdldpEVWDGSVGGELNLYGVKLDLKridvpewaaseeELRERL 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1327 EKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESL--QQKLESSQLQIAGLEHLRELQPELDE 1404
Cdd:pfam12128  607 DKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLfdEKQSEKDKKNKALAERKDSANERLNS 686

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1405 L---QKLISEKEEDVS-YLSGQLRE----KEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERI-KQLQVELCEMKQK 1475
Cdd:pfam12128  687 LeaqLKQLDKKHQAWLeEQKEQKREarteKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALeTWYKRDLASLGVD 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1476 PEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDtieHLTKSLADVESHVSaqnkekdRVLGRLALLQEE 1555
Cdd:pfam12128  767 PDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRP---RLATQLSNIERAIS-------ELQQQLARLIAD 836

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1556 ----RDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKL-VKEIESLKSSKIAESSEWQEKHKELQKEYEILLQSY 1630
Cdd:pfam12128  837 tklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKEDAnSEQAQGSIGERLAQLEDLKLKRDYLSESVKKYVEHF 916


                   ...
gi 1622909118 1631 ENV 1633
Cdd:pfam12128  917 KNV 919
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2710-2934 2.00e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2710 EERVAELARDLVEMEQKLLMVTKENK--DLTAQIQSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQqglln 2787
Cdd:COG3206    181 EEQLPELRKELEEAEAALEEFRQKNGlvDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDA----- 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2788 rerhallsettfsmdLPEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDhlwnelekfrks 2867
Cdd:COG3206    256 ---------------LPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQ------------ 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 2868 eegkqrsaaqpatslaevQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEYQ 2934
Cdd:COG3206    309 ------------------QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2022-2233 2.10e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2022 LKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAAR 2101
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2102 VLADNLKLKKELQS-------NKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTL 2174
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 2175 NKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQTKEEE 2233
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAA 236
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
2742-2949 2.62e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.47  E-value: 2.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2742 QSFGRSMSSLQNSRDHANEELDELKRKYDASLKELAQLKEQQGLLnrerhallsettfsmDLPEENSLsylekLNQQLLS 2821
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLV---------------DLSEEAKL-----LLQQLSE 223

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2822 KDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWN--ELEKFRKSEEGKQRSAAQPATSLAE----VQSLKKAMSSL 2895
Cdd:COG3206    224 LESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPnhpdVIALRAQIAAL 303

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118 2896 QNDRDRLLKE-LKNLQQQYLQINQEITELRplkAQLQEYQDKTKTFQIMQEELRQ 2949
Cdd:COG3206    304 RAQLQQEAQRiLASLEAELEALQAREASLQ---AQLAQLEARLAELPELEAELRR 355
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 690-1125 2.69e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.77  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  690 HQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSVVTE 769
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  770 LRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQL- 848
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLl 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  849 ----QNKESEVLEGAERVRHISSKVEELSQALS---------QKELEIAKMDQLLLEKKRDVETLQQTIEE-KDQQVTEI 914
Cdd:COG1196    495 llleAEADYEGFLEGVKAALLLAGLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYlKAAKAGRA 574

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  915 SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspaGLISKEELQHEFDLLKK 994
Cdd:COG1196    575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEA---ALRRAVTLAGRLREVTL 651

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  995 ENEQRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKEYSEKcvtsKCQEIEISLKQTI 1074
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEE----ERLEEELEEEALE 727

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1622909118 1075 SEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISE 1125
Cdd:COG1196    728 EQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2144-2338 2.76e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2144 KEKKNMQEKLDALRREKVHLEETIGEIQVTLNKKDKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVIDEAKKWERKF 2223
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2224 SDAI-------QTKEEEIRLKEENCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESK---AQTEVQLQQKVCDTLQGE 2293
Cdd:COG4942    107 AELLralyrlgRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALraeLEAERAELEALLAELEEE 186

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1622909118 2294 NKELLSQLEETRHLYHNSQNELAKLESELNILKDQLTDLSNSLEK 2338
Cdd:COG4942    187 RAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 693-1250 2.85e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.52  E-value: 2.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  693 ELERLKSQILELELNFHKAQE---IYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLAQVKELSV-VT 768
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEErlaKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKeFA 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  769 ELRAQVRQLEMNLAEAERQRrfdYESQTAHHNL------LTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 842
Cdd:TIGR02169  382 ETRDELKDYREKLEKLKREI---NELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  843 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVE-----------TLQQTIEEKDQQV 911
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEvlkasiqgvhgTVAQLGSVGERYA 538

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  912 TEISFSMTEKMVQLNEEKFSLGVE-IKTLKEQ---------LNLLSRAE-------------------------EAKKEQ 956
Cdd:TIGR02169  539 TAIEVAAGNRLNNVVVEDDAVAKEaIELLKRRkagratflpLNKMRDERrdlsilsedgvigfavdlvefdpkyEPAFKY 618

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  957 VEEDNEVVSGLKQNYDEMSPAGLISKEElqhefDLLKKENEQR--KRKLQAALINRKELLQRVSRLEEELANLKDQskKE 1034
Cdd:TIGR02169  619 VFGDTLVVEDIEAARRLMGKYRMVTLEG-----ELFEKSGAMTggSRAPRGGILFSRSEPAELQRLRERLEGLKRE--LS 691

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1035 IPLSESERGEVEEDKENKEYSEkcvtskcqeieisLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTN 1114
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSD-------------ASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1115 QIDLLQAEISENQVIIQKLTTSNTDASDGDSVALVKETVVISPPGTDSGEHWKP---ELEEKILALEKEKEQLQKKLQE- 1190
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEArlrEIEQKLNRLTLEKEYLEKEIQEl 838

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1191 -----ALTSRKAILKKAQE----KERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQVRE 1250
Cdd:TIGR02169  839 qeqriDLKEQIKSIEKEIEnlngKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEE 907
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1471-2197 3.20e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.29  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1471 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLArdtieHLTKSLADVESHVSAQNKEKDRVLGRL- 1549
Cdd:pfam12128  215 KSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLS-----HLHFGYKSDETLIASRQEERQETSAELn 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1550 ALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKE-IESLKSSKIAESSeWQEKHKELQKEYEILLQ 1628
Cdd:pfam12128  290 QLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAdIETAAADQEQLPS-WQSELENLEERLKALTG 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1629 SYENVSNEAERIQHVVeaVRQEKQELYGKLRSTEANKKETEKQLQEAEKEMEEMKEKMRKfakSKQQKILELEEENDRLR 1708
Cdd:pfam12128  369 KHQDVTAKYNRRRSKI--KEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELRE---QLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1709 AEVHPAGG--TAKECMETLLSSNASMKEEVERVKMEYETLSKKFQSLMSEK---DSLSEEvQDLKHQLES---NVSKQAN 1780
Cdd:pfam12128  444 SRLGELKLrlNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELrqaRKRRDQ-ASEALRQASrrlEERQSAL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1781 LEATEKHDNQMNVTEEATQSIPGETEDQDSLSMSTRPAC-SESVPSENSANPAVSEDVSS------HDEINNYLQQIDQL 1853
Cdd:pfam12128  523 DELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHrTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEEL 602

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1854 KERIAGLEEEKQKNKEFSQTLEnernallSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTklketaeEEKDDLEER 1933
Cdd:pfam12128  603 RERLDKAEEALQSAREKQAAAE-------EQLVQANGELEKASREETFARTALKNARLDLRRLF-------DEKQSEKDK 668

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1934 LMNQLAELNGSIGNYCQDVtDAQIKneLLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQgAQKEPGNKS 2013
Cdd:pfam12128  669 KNKALAERKDSANERLNSL-EAQLK--QLDKKHQAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLK-AAIAARRSG 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2014 HAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD 2093
Cdd:pfam12128  745 AKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2094 DTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLER-RLEQAEEKHLKEKKNMQEkldaLRREKVHLEETIGEIQV 2172
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGlRCEMSKLATLKEDANSEQ----AQGSIGERLAQLEDLKL 900

                          730       740
                   ....*....|....*....|....*
gi 1622909118 2173 TLNKKDKEIQQVQENLDSTVAQLAA 2197
Cdd:pfam12128  901 KRDYLSESVKKYVEHFKNVIADHSG 925
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2752-3007 3.31e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2752 QNSRDHANEELDELKRKYDASLKELAQLKEQQgllnrerhallsettfsmdlpeenslsylEKLNQQLLSKDEQLLHLSS 2831
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEE-----------------------------KALLKQLAALERRIAALAR 69

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2832 QLEDSYNQVQSFSKAMASLQNERDHLWNELEKfRKSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRD-RLLKEL-KNL 2909
Cdd:COG4942     70 RIRALEQELAALEAELAELEKEIAELRAELEA-QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRlQYLKYLaPAR 148

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2910 QQQYLQINQEITELRPLKAQLQEYQDKtktfqimQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQ 2989
Cdd:COG4942    149 REQAEELRADLAELAALRAELEAERAE-------LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221

                          250
                   ....*....|....*...
gi 1622909118 2990 VSHLQNLIRELRSSSSQA 3007
Cdd:COG4942    222 AEELEALIARLEAEAAAA 239
PRK09039 PRK09039
peptidoglycan -binding protein;
2701-2836 3.35e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 42.65  E-value: 3.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2701 IMRNETETAEERVAELARDLVEMEQKLLMVTKENKDLTAQIqsfgrsmSSLQNSRDHANEELDELKRKYDASLKELAQLK 2780
Cdd:PRK09039    43 FLSREISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSV-------ANLRASLSAAEAERSRLQALLAELAGAGAAAE 115

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118 2781 EQQGLLNRErhaLLSETTFSmdlpeENSLSYLEKLNQQLLSKDEQLLHLSSQLEDS 2836
Cdd:PRK09039   116 GRAGELAQE---LDSEKQVS-----ARALAQVELLNQQIAALRRQLAALEAALDAS 163
alph_xenorhab_A NF033928
alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding ...
 2045-2214 3.47e-03

alpha-xenorhabdolysin family binary toxin subunit A; Alpha-xenorhabdolysin was the founding member of a family of alpha-helical pore-forming binary toxins. YaxAB from Yersinia enterocolitica has been studied structurally. This HMM represents subunit A proteins such as XaxA and YaxA, capable of binding to the membrane even in the absence of the B subunit. This family is related to the Bacillus haemolytic enterotoxin family (see PF05791.9), although thresholds for this HMM are set to exclude that family.


Pssm-ID: 468250 [Multi-domain]  Cd Length: 340  Bit Score: 42.67  E-value: 3.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2045 ALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFkvlLDDTQSEAARVLADNLKLKKELQSNK----ESV 2120
Cdd:NF033928    88 PIIDLINEMPIIKRGDLTEEELSELPPIPLSSDDKEIVKELKEI---LEDLKNDIKDYQQKADDVKKELDDFEndlrEEL 164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2121 KSQMKQKDEDLERRLEQAEEKHLKEK-KNMQEKLDALRREKVHLEETIG----------------------EIQVTLNKK 2177
Cdd:NF033928   165 LPQLKLKKKLYDDNLGSDSIEELREKiDQLEKEIEQLNKEYDDYVKLSFtglaggpiglaitggifgskaeKIRKEKNAL 244

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1622909118 2178 DKEIQQVQENLDSTVAQLAAFTKSMSSLQDDRDRVID 2214
Cdd:NF033928   245 IQEIDELQEQLKKKNALLGSLERLQTSLDDILTRMED 281
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1310-1503 3.49e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1310 TSVAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLES--SQL 1387
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGEraRAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1388 QIAG------------------LEHLRELQPELDELQKLISEKEEDVsylsGQLREKEAALTKIQTEIIEQEDLIKALHT 1449
Cdd:COG3883     96 YRSGgsvsyldvllgsesfsdfLDRLSALSKIADADADLLEELKADK----AELEAKKAELEAKLAELEALKAELEAAKA 171

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1622909118 1450 QLEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEA 1503
Cdd:COG3883    172 ELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAA 225
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2325-3191 3.74e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2325 LKDQLTDLSNSLEKCKE---QKENLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKMISLLSGKEE 2401
Cdd:TIGR00606  222 IRDQITSKEAQLESSREivkSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2402 AIQvaiaELRQQHDKEIKELENLLSQEeeenivleeenKKAVDKTNQLMETLNAIKKENIQQKAQLdsfvksmsSLQNDR 2481
Cdd:TIGR00606  302 QLN----DLYHNHQRTVREKERELVDC-----------QRELEKLNKERRLLNQEKTELLVEQGRL--------QLQADR 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2482 DRIVGDYQQLEERHLSVILEKDQLIQEAAAENnKLKEEIRGLRSHMDDLNSENAKLDAELiQYREDLNQVISIKDSQQKQ 2561
Cdd:TIGR00606  359 HQEHIRARDSLIQSLATRLELDGFERGPFSER-QIKNFHTLVIERQEDEAKTAAQLCADL-QSKERLKQEQADEIRDEKK 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2562 LLEAQLQQNKEL----KNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESlkVSVSQLTRQVTALQEEG---- 2633
Cdd:TIGR00606  437 GLGRTIELKKEIlekkQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKN--SLTETLKKEVKSLQNEKadld 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2634 -TLGIYHAQLKVKEEELQRLSALLSSSQKRITELEEELVCVQKEAAKKVGEIED-KLKKELKHLHHDagiMRNETETAEE 2711
Cdd:TIGR00606  515 rKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfPNKKQLEDWLHS---KSKEINQTRD 591

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2712 RVAELARDLVEMEQKLLMVTKENKDLTAQIQSFGRSMSSLQNSRDHaNEELDELKRKYDASLKELAQLKEQQGLLNRERH 2791
Cdd:TIGR00606  592 RLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2792 ALLSETTFSMDL------PEENSLSYLEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR 2865
Cdd:TIGR00606  671 QLTDENQSCCPVcqrvfqTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2866 KSEEGKQRSAAQPATSLAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELRPLKAQLQEyQDKTKTFQimqe 2945
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQG-SDLDRTVQ---- 825

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2946 ELRQENLSWQHELhqlrmEKSSWEIHERRMkeqylmAISDKDQQVSHLQNLIRELRSSSSQAQPLKVQYQRQAspetsas 3025
Cdd:TIGR00606  826 QVNQEKQEKQHEL-----DTVVSKIELNRK------LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE------- 887

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3026 pDGSQNLIYETELLRNQLNDSLKEIHQKELRIQQLNSKFSQLLEEKNTLSIQLCDTSQSLRENQQhygDLLNHCAVLEKQ 3105
Cdd:TIGR00606  888 -EQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK---NIHGYMKDIENK 963

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 3106 VQELQAVSKEKGPLNIDVApGAPQEKNGVHRKSDPEELREPQQSFSEAQQQLC-----NTRQEVNELRKLLEEERDQRVA 3180
Cdd:TIGR00606  964 IQDGKDDYLKQKETELNTV-NAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnLTLRKRENELKEVEEELKQHLK 1042

                          890
                   ....*....|.
gi 1622909118 3181 AENALSLAEEQ 3191
Cdd:TIGR00606 1043 EMGQMQVLQMK 1053
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1169-1245 3.84e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.15  E-value: 3.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1169 ELEEKILALEKEKEQLQKKLQEALTSRKAILKK----AQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQL 1244
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERLAELRDelaeLEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494


                   .
gi 1622909118 1245 Q 1245
Cdd:COG0542    495 A 495
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1459-1711 4.15e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 4.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1459 DERIKQLQ----VELCEMKQK--PEEIEEESRAkqqiQRKLQAALISRKEALKENKSLQEELSLAR-----DTIEHLTKS 1527
Cdd:PRK05771    19 DEVLEALHelgvVHIEDLKEElsNERLRKLRSL----LTKLSEALDKLRSYLPKLNPLREEKKKVSvksleELIKDVEEE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1528 LADVESHVSAQNKEKDRvlgrlalLQEERDKLITEMDR-SLLENQSLS----GSCESLKLALEGLTEDKEKLVKEIESLK 1602
Cdd:PRK05771    95 LEKIEKEIKELEEEISE-------LENEIKELEQEIERlEPWGNFDLDlsllLGFKYVSVFVGTVPEDKLEELKLESDVE 167

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1603 SSKIAESSEwqEK-------HKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELygklrsteankketekqlQEA 1675
Cdd:PRK05771   168 NVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------------------EEI 227

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1622909118 1676 EKEMEEMKEKMRKFAKSKQQKILELEE--ENDRLRAEV 1711
Cdd:PRK05771   228 EKERESLLEELKELAKKYLEELLALYEylEIELERAEA 265
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1848-2001 4.17e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 4.17e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1848 QQIDQLKERIAGLEEEKQKNKEFSQTLENERNALLSQISTKDGELKLLQEEVSKMNLLNQQIQEELSRVTKLKE------ 1921
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1922 ---TAEEEKDDLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEY 1998
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1622909118 1999 LEK 2001
Cdd:COG1579    177 LAL 179
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1922-2153 4.22e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 42.99  E-value: 4.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1922 TAEEEKDDLEERLMN----QLAELNGSIGNYcqdvtdaqiKNELLESEMKNLKKCVSELEEEKQqlvKEKTKVESEIRKE 1997
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNE---------RLRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1998 YLEKIQGAQKEPGNKShakELQELLKEKQQEVKQLQKDCIRYQEKISALE---------------RTVKA---------- 2052
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELENEIKELEQEIERLEpwgnfdldlslllgfKYVSVfvgtvpedkl 157

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2053 LEFVQTESQKDLEITKEN-------LAQAVEHRKKAQAELASFKVLLDDTQSE--AARVLADNLKLKKELQSNKESVKSQ 2123
Cdd:PRK05771   158 EELKLESDVENVEYISTDkgyvyvvVVVLKELSDEVEEELKKLGFERLELEEEgtPSELIREIKEELEEIEKERESLLEE 237

                          250       260       270
                   ....*....|....*....|....*....|..
gi 1622909118 2124 MKQKDEDLERRLEQAEEK--HLKEKKNMQEKL 2153
Cdd:PRK05771   238 LKELAKKYLEELLALYEYleIELERAEALSKF 269
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1323-1520 4.68e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1323 ETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAglehlrELQPEL 1402
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIE------ERREEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1403 DELQKLISEKEEDVSYLS-----------------------------GQLREKEAALTKIQTEIIEQEDLIKALHTQLEM 1453
Cdd:COG3883     89 GERARALYRSGGSVSYLDvllgsesfsdfldrlsalskiadadadllEELKADKAELEAKKAELEAKLAELEALKAELEA 168

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1454 QAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDT 1520
Cdd:COG3883    169 AKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAA 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1376-1605 5.15e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 5.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1376 ESLQQKLESSQLQIAGLEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALtkIQTEIIEQEDLIKALHTQLEmqa 1455
Cdd:COG4913    238 ERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLEL--LEAELEELRAELARLEAELE--- 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1456 kEHDERIKQLQVELCEMKQKPEEIeeESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHV 1535
Cdd:COG4913    313 -RLEARLDALREELDELEAQIRGN--GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA 389

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1536 SAQnkeKDRVLGRLALLQEERDKLITemdrsllenqslsgsceslklALEGLTEDKEKLVKEIESLKSSK 1605
Cdd:COG4913    390 AAL---LEALEEELEALEEALAEAEA---------------------ALRDLRRELRELEAEIASLERRK 435
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1312-1562 5.20e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.20  E-value: 5.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1312 VAQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHEAEVRAESLQQKLESSQLQIAG 1391
Cdd:COG4372     47 LEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQD 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1392 LEHLR-ELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEIieQEDLIKALHTQLEMQAKEHDERIKQLQVELC 1470
Cdd:COG4372    127 LEQQRkQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL--QALSEAEAEQALDELLKEANRNAEKEEELAE 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1471 EMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADVESHVSAQNKEKDRVLGRLA 1550
Cdd:COG4372    205 AEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAILVEKDTEEEELEIAALE 284

                          250
                   ....*....|..
gi 1622909118 1551 LLQEERDKLITE 1562
Cdd:COG4372    285 LEALEEAALELK 296
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1314-1675 5.34e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.70  E-value: 5.34e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1314 QIKAQLKEIETE-----KEKLELKISSTTSELTKKSEEVFQLQDQ-------INKQGLEIESLKTASHEAEVRAESLQQK 1381
Cdd:TIGR04523  285 ELEKQLNQLKSEisdlnNQKEQDWNKELKSELKNQEKKLEEIQNQisqnnkiISQLNEQISQLKKELTNSESENSEKQRE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1382 LESSQLQIAGLEhlRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQT------EIIEQEDLIKALHTQLEMQA 1455
Cdd:TIGR04523  365 LEEKQNEIEKLK--KENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKlqqekeLLEKEIERLKETIIKNNSEI 442

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1456 KEHDERIKQLQVELCEMKQKPEEIEEE----SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARDTIEHLTKSLADV 1531
Cdd:TIGR04523  443 KDLTNQDSVKELIIKNLDNTRESLETQlkvlSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSL 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1532 ESHVSAQNKEKDRVLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKL-----ALEGLTEDKEKLVKEIESLKSSKI 1606
Cdd:TIGR04523  523 KEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELkqtqkSLKKKQEEKQELIDQKEKEKKDLI 602

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1622909118 1607 AESSEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEA 1675
Cdd:TIGR04523  603 KEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRNKWPEIIKKIKES 671
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2508-2977 5.73e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.36  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2508 EAAAEN-NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVISIKDSQQKQL--LEAQLQQNKELKNKYAKLEEKL 2584
Cdd:PRK03918   161 ENAYKNlGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELpeLREELEKLEKEVKELEELKEEI 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2585 KESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTALQE-----------EGTLGIYHAQLKVKEEELQRLS 2653
Cdd:PRK03918   241 EELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEYLDELREIEKRLSRLE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2654 ALLSSSQKRITELE------EELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2727
Cdd:PRK03918   321 EEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2728 LMVTKENKDLTAQIQSFGRSMSSLQNS---------------RDHANEELDELKRKYDASLKELAqlKEQQGLLNRERHA 2792
Cdd:PRK03918   401 EEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE--KELKEIEEKERKL 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2793 LLSETTFSMDLPEENSLSYLEKLNQQLLSKDEQL-LHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFrksEEGK 2871
Cdd:PRK03918   479 RKELRELEKVLKKESELIKLKELAEQLKELEEKLkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL---EELK 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2872 QRSAAqpatslaevqsLKKAMSSLQNDRDRLLKELKNLQQQYL-QINQEITELRPLKAQLQEYQDKTKTFQIMQEELRQE 2950
Cdd:PRK03918   556 KKLAE-----------LEKKLDELEEELAELLKELEELGFESVeELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          490       500
                   ....*....|....*....|....*..
gi 1622909118 2951 NLSWQHELHQLRMEKSSWEIHERRMKE 2977
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEE 651
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 839-1053 5.81e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  839 TLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSM 918
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  919 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEMspagliskEELQHEFDLLKKENE 997
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAEL--------EAKLAELEALKAELE 167

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118  998 QRKRKLQAALINRKELLQRVSRLEEELANLKDQSKKEIPLSESERGEVEEDKENKE 1053
Cdd:COG3883    168 AAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 861-1437 6.01e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 6.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  861 RVRHISSKVEELSQALSQKELEIAKMDQLLLEKKRDVETLQQTIEEKDQQVTEISFSMTE---KMVQLNEEKFSLGVEIK 937
Cdd:TIGR04523   34 EEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKnkdKINKLNSDLSKINSEIK 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  938 TLKEQLNL----LSRAEEAKKEQVEEDNEVVSGLKQNYDEMSPAGLI------SKEELQHEFDLLKKENEQRK------- 1000
Cdd:TIGR04523  114 NDKEQKNKleveLNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKyndlkkQKEELENELNLLEKEKLNIQknidkik 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1001 ---RKLQAALINRKELLQRVSRLEEELANLKDQS---KKEIPLSESERGEVEEDKENKEYSEKCVTSKCQEIeislKQTI 1074
Cdd:TIGR04523  194 nklLKLELLLSNLKKKIQKNKSLESQISELKKQNnqlKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI----KKQL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1075 SEKEVELEHIRKDLEEKMAAEEQLQA------------LVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTtsntdasd 1142
Cdd:TIGR04523  270 SEKQKELEQNNKKIKELEKQLNQLKSeisdlnnqkeqdWNKELKSELKNQEKKLEEIQNQISQNNKIISQLN-------- 341

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1143 gDSVALVKETVVISppgTDSGEHWKPELEEKILALEKEKEQLQKKLQE--ALTSRKAIL----KKAQEKERHLREELKQQ 1216
Cdd:TIGR04523  342 -EQISQLKKELTNS---ESENSEKQRELEEKQNEIEKLKKENQSYKQEikNLESQINDLeskiQNQEKLNQQKDEQIKKL 417

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1217 KDDYNRLQEQFDEQSKENENIGDQLRQL--QIQVRESIDGKLPSPDQQewcsptpgLEEPLFKATEQHHTQPVLESNLCP 1294
Cdd:TIGR04523  418 QQEKELLEKEIERLKETIIKNNSEIKDLtnQDSVKELIIKNLDNTRES--------LETQLKVLSRSINKIKQNLEQKQK 489

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1295 DWPSHSEDASALQGGTSvaQIKAQLKEIETEKEKLELKISSTTSELTKKSEEVFQLQDQINK--QGLEIESLKTASHEAE 1372
Cdd:TIGR04523  490 ELKSKEKELKKLNEEKK--ELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddFELKKENLEKEIDEKN 567

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1622909118 1373 VRAESLQQ---KLESSQLQIAglEHLRELQPELDELQKLISEKEEDVSYLSGQLREKEAALTKIQTEI 1437
Cdd:TIGR04523  568 KEIEELKQtqkSLKKKQEEKQ--ELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSII 633
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 259-1092 6.09e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.65  E-value: 6.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  259 QQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQIEAEHNTLRNTVETEREESKILLEKMELEVAE 338
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIES 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  339 RKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKD 418
Cdd:pfam02463  256 SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  419 EQAVQSAQTIEQLEDQLQQKSKEISQFLNRLPLQQHETASQTCFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLS 498
Cdd:pfam02463  336 EIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELAR 415

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  499 SIELEELKAENEKLSSQITLLEAQNRIGEADREVSEISIVDDAnkrsssTEESGQDVLENTFSQKHKELSVLLLEMKEAQ 578
Cdd:pfam02463  416 QLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQEL------KLLKDELELKKSEDLLKETQLVKLQEQLELL 489

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  579 EEIAFLK--LQLQGKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDTGQNFPLMPNEESSLPAVEKEQASTEHQNRT 656
Cdd:pfam02463  490 LSRQKLEerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRA 569

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  657 SEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQEIYEKNLDEKAKEISNLNQLIEEF 736
Cdd:pfam02463  570 LTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLR 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  737 KKNADNNSSAFTALSEERDQLLAQVKELSVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHNLLTEQIHSLSIEAKS- 815
Cdd:pfam02463  650 KGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQe 729

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  816 KDVKIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEKKR 895
Cdd:pfam02463  730 AQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEE 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  896 DVETLQQT------------IEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEV 963
Cdd:pfam02463  810 LKEEAELLeeeqllieqeekIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELE 889

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  964 VSGLKQNYDEMSPAGLISKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEE-LANLKDQSKKEIPLSESER 1042
Cdd:pfam02463  890 SKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEkEENNKEEEEERNKRLLLAK 969

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1043 GEVEEDKENKEYSEKCVTSKCQEIEISLKQTISEKEVELEHIRKDLEEKM 1092
Cdd:pfam02463  970 EELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
mukB PRK04863
chromosome partition protein MukB;
2707-3009 6.47e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 42.64  E-value: 6.47e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2707 ETAEERVAELARDLVEMEQKllmvtkenkdlTAQIQSFGRSMSSLQ---NSRDHANEELDELKRKYDASLKELAQLKEQQ 2783
Cdd:PRK04863   890 ETLADRVEEIREQLDEAEEA-----------KRFVQQHGNALAQLEpivSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQA 958

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2784 GLLN--RERHALLSETTFSMDLPEENSLSylEKLNQQLLSKDEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNEL 2861
Cdd:PRK04863   959 FALTevVQRRAHFSYEDAAEMLAKNSDLN--EKLRQRLEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQML 1036

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2862 ekfrksEEGKQRSAAQ--PATSLAEVQslkkamssLQNDRDRLLKELKNLQQQYLQINQEIT----ELRPLKAQLQEYQd 2935
Cdd:PRK04863  1037 ------QELKQELQDLgvPADSGAEER--------ARARRDELHARLSANRSRRNQLEKQLTfceaEMDNLTKKLRKLE- 1101

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2936 ktKTFQIMQEELRQENLSWQHELHQLRMEKSSWEIHERR---MKEQYLMAISDKDQ-----QVSHLQNLIRELRSSSSQA 3007
Cdd:PRK04863  1102 --RDYHEMREQVVNAKAGWCAVLRLVKDNGVERRLHRRElayLSADELRSMSDKALgalrlAVADNEHLRDVLRLSEDPK 1179


                   ..
gi 1622909118 3008 QP 3009
Cdd:PRK04863  1180 RP 1181
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 2171-2575 6.68e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.35  E-value: 6.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2171 QVTLNKKDKEIQQVQEnLDSTVAQLAAFTKSMSSLQDDRdRVIDEAKKWERKFSDAIQTKEEEIRLKEENCSVlkDQLRQ 2250
Cdd:PRK10929    34 QAKAAKTPAQAEIVEA-LQSALNWLEERKGSLERAKQYQ-QVIDNFPKLSAELRQQLNNERDEPRSVPPNMST--DALEQ 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2251 msihmEELKINISRLEHDKQiweskAQTEVQLQQKVCDTL------QGENKELLSQLEETRHLYHN-----SQNELAKLE 2319
Cdd:PRK10929   110 -----EILQVSSQLLEKSRQ-----AQQEQDRAREISDSLsqlpqqQTEARRQLNEIERRLQTLGTpntplAQAQLTALQ 179

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2320 SELNILKDQLtdlsNSLEKCKEQKENLEGIIRQQeadIQNSKFSYEQLETDLQAsreltsrLHEEINMKEQKMISLLSGK 2399
Cdd:PRK10929   180 AESAALKALV----DELELAQLSANNRQELARLR---SELAKKRSQQLDAYLQA-------LRNQLNSQRQREAERALES 245

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2400 EEAIQVAIAELRQQHDKEIK---ELENLLSQEEEENIVLEEENKKAVDKTNQLMETLNAIKkeniQQKAQLDSfvksmss 2476
Cdd:PRK10929   246 TELLAEQSGDLPKSIVAQFKinrELSQALNQQAQRMDLIASQQRQAASQTLQVRQALNTLR----EQSQWLGV------- 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2477 lqndrDRIVGDYQQLEERHLSVILEKDQLIQEAAaennklkeEIRGLRSHMDDLNSENAKLDaeliQYREDLNQVISikd 2556
Cdd:PRK10929   315 -----SNALGEALRAQVARLPEMPKPQQLDTEMA--------QLRVQRLRYEDLLNKQPQLR----QIRQADGQPLT--- 374

                          410
                   ....*....|....*....
gi 1622909118 2557 SQQKQLLEAQLQQNKELKN 2575
Cdd:PRK10929   375 AEQNRILDAQLRTQRELLN 393
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2479-2765 6.86e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.21  E-value: 6.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2479 NDRDRIVGDY-------QQLEErhlsvileKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLdAELIQYREDLNQV 2551
Cdd:COG4913    593 DDRRRIRSRYvlgfdnrAKLAA--------LEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV 663

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2552 isikDSQQKQL--LEAQLQQNKELKNKYAKLEEKLKESEEANEDLQRSSNALQEEKRDLSKEIESLKVSVSQLTRQVTAL 2629
Cdd:COG4913    664 ----ASAEREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAA 739

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 2630 QEEGTLGiYHAQLkvkeeELQRLSALLSSSQKRITE-LEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNETET 2708
Cdd:COG4913    740 EDLARLE-LRALL-----EERFAAALGDAVERELREnLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLES 813

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1622909118 2709 AEERVAELAR----DLVEMEQKLL-MVTKENKDLTAQIQsfgrsmSSLQNSRDHANEELDEL 2765
Cdd:COG4913    814 LPEYLALLDRleedGLPEYEERFKeLLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 898-1605 6.98e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.41  E-value: 6.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  898 ETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEA----KKEQVEEDNEVVSGLKQNYDE 973
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  974 MSPAGLISKeelqhefDLLKKENEQRKrKLQAALINRKELLQRVSRLeeeLANLKDQSKKEIplsesergeVEEDKENke 1053
Cdd:pfam15921  154 LEAAKCLKE-------DMLEDSNTQIE-QLRKMMLSHEGVLQEIRSI---LVDFEEASGKKI---------YEHDSMS-- 211

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1054 ysekcvTSKCQEIEISLKQTISEKEVELEHIRKDLeekMAAEEQLQALVKEMNQTLQDKTNQ-IDLLQAEISENQVIIQK 1132
Cdd:pfam15921  212 ------TMHFRSLGSAISKILRELDTEISYLKGRI---FPVEDQLEALKSESQNKIELLLQQhQDRIEQLISEHEVEITG 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1133 LTTSNTDASDgDSVALVKETVVISPPGTDSGEHWKPELEEkilaLEKEKEQLQKKLQEAltsrkaiLKKAQEKERHLREE 1212
Cdd:pfam15921  283 LTEKASSARS-QANSIQSQLEIIQEQARNQNSMYMRQLSD----LESTVSQLRSELREA-------KRMYEDKIEELEKQ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1213 LKQQKDDYNRLQEQFDEQSKENENIGDQLRQL--QIQVRESIDGKLPSPDQQEWCSPTPGleeplfKATEQHHTQPVLES 1290
Cdd:pfam15921  351 LVLANSELTEARTERDQFSQESGNLDDQLQKLlaDLHKREKELSLEKEQNKRLWDRDTGN------SITIDHLRRELDDR 424

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1291 NLcpdWPSHSEDASALQGGTSVAQIKAQLKEIETEKEKLElKISSTTSELTKKSEEVFQLQDQINKQGLEIESLKTASHE 1370
Cdd:pfam15921  425 NM---EVQRLEALLKAMKSECQGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1371 AEVRAESLQQKLESSQLQIAGLEHLRELQpeLDELQKLISEKEEdvsylsgqlrekeaaLTKIQTEIieqedlikalhTQ 1450
Cdd:pfam15921  501 LTASLQEKERAIEATNAEITKLRSRVDLK--LQELQHLKNEGDH---------------LRNVQTEC-----------EA 552

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1451 LEMQAKEHDERIKQLQVELCEMKQKPEEIEEESRAKQQIQRKLQAALISRKEALKENKSLQEElslARDTIEHLTKSLAD 1530
Cdd:pfam15921  553 LKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDK---KDAKIRELEARVSD 629

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1622909118 1531 VE-SHVSAQNKEKDRvLGRLALLQEERDKLITEMDRSLLENQSLSGSCESLKLALEGLTEDKEKLVKEIE-SLKSSK 1605
Cdd:pfam15921  630 LElEKVKLVNAGSER-LRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKmQLKSAQ 705
46 PHA02562
endonuclease subunit; Provisional
 668-909 7.45e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  668 ELKSTKQDCDKSLSAVPDIGQCHQDELERLKSQILElelNFHKAQEIYEKNLdEKAK----EISNLNQLIEEFKKNADNN 743
Cdd:PHA02562   178 ELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGE---NIARKQNKYDELV-EEAKtikaEIEELTDELLNLVMDIEDP 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  744 SSAFTALSEERDQLLAQVKELSVVTELraqvrqlemnlaeaerqrrfdYESQ----TAHHNLLTEQIHSLSIEAKSKDV- 818
Cdd:PHA02562   254 SAALNKLNTAAAKIKSKIEQFQKVIKM---------------------YEKGgvcpTCTQQISEGPDRITKIKDKLKELq 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  819 ----KIEVLQNELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQlllEKK 894
Cdd:PHA02562   313 hsleKLDTAIDELEEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD---ELD 389

                          250
                   ....*....|....*
gi 1622909118  895 RDVETLQQTIEEKDQ 909
Cdd:PHA02562   390 KIVKTKSELVKEKYH 404
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 1316-1622 8.00e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 42.15  E-value: 8.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1316 KAQLKEIETEKEKLELKISSTTSELTKKSEEVfqLQDQINKQGLEIESLKTASheaeVRAESLQQKLESSQLQIAGL--- 1392
Cdd:PLN03229   428 KTPVRELEGEVEKLKEQILKAKESSSKPSELA--LNEMIEKLKKEIDLEYTEA----VIAMGLQERLENLREEFSKAnsq 501

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1393 EHLreLQPEL-DELQKLISEKEEDVS----YLSgqLREKEAALTKIQTEIIEQEDLIKALHTQLEMqakehDERIKQLqV 1467
Cdd:PLN03229   502 DQL--MHPVLmEKIEKLKDEFNKRLSrapnYLS--LKYKLDMLNEFSRAKALSEKKSKAEKLKAEI-----NKKFKEV-M 571

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1468 ELCEMKQKPEEIEEESrAKQQIQRKLQAALISRKEALKENKSLQEEL-----SLARDTIEHLTKSLADVESHVSAQNKEK 1542
Cdd:PLN03229   572 DRPEIKEKMEALKAEV-ASSGASSGDELDDDLKEKVEKMKKEIELELagvlkSMGLEVIGVTKKNKDTAEQTPPPNLQEK 650

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1543 drvlgrLALLQEERDKLITEMDRSllenQSLSGSCESLKL--ALEGLTEDKEkLVKEIESLKSS---KIAE---SSEWQE 1614
Cdd:PLN03229   651 ------IESLNEEINKKIERVIRS----SDLKSKIELLKLevAKASKTPDVT-EKEKIEALEQQikqKIAEalnSSELKE 719


                   ....*...
gi 1622909118 1615 KHKELQKE 1622
Cdd:PLN03229   720 KFEELEAE 727
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
502-1029 8.89e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 41.95  E-value: 8.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  502 LEELKAENEKLSSQiTLLEAQNRIGEADREV-SEISIVDDANKRSSSTEESGQDVLEnTFSQKHKELSVLLLEMKEAQEE 580
Cdd:PRK02224   189 LDQLKAQIEEKEEK-DLHERLNGLESELAELdEEIERYEEQREQARETRDEADEVLE-EHEERREELETLEAEIEDLRET 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  581 IAFLKlqlqgKRAEEGDHEVLDQKEMKQMEGEGIAPIKMEVFLEDtgqnfplmpneeSSLPAVEKEQASTEHQNRTSEEi 660
Cdd:PRK02224   267 IAETE-----REREELAEEVRDLRERLEELEEERDDLLAEAGLDD------------ADAEAVEARREELEDRDEELRD- 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  661 SLNDAGVELKSTKQDCDKSLSAVPDigqcHQDELERLKSQILELELNFHKAQEiyekNLDEKAKEISNLNQLIEEFKKNA 740
Cdd:PRK02224   329 RLEECRVAAQAHNEEAESLREDADD----LEERAEELREEAAELESELEEARE----AVEDRREEIEELEEEIEELRERF 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  741 DNNSSAFTALSEERDQLLAQVKEL-SVVTELRAQVRQLEMNLAEAERQRRFDYESQTAHHnlLTEQIHSLSIEakSKDVK 819
Cdd:PRK02224   401 GDAPVDLGNAEDFLEELREERDELrEREAELEATLRTARERVEEAEALLEAGKCPECGQP--VEGSPHVETIE--EDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  820 IEVLQNELDDVQLQFS------EQSTLIRSLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEIAKMDQLLLEK 893
Cdd:PRK02224   477 VEELEAELEDLEEEVEeveerlERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEK 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  894 KRDVETLQQTIEEKDQQVTEISFSMTE---------KMVQLNEEKFSLGVEIKTLKEQLNLLSRAEEAKKEQVEEDNEVV 964
Cdd:PRK02224   557 REAAAEAEEEAEEAREEVAELNSKLAElkeriesleRIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERK 636

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1622909118  965 SGLKQNYDEMspagliSKEELQHEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKD 1029
Cdd:PRK02224   637 RELEAEFDEA------RIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEE 695
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 137-387 8.93e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 8.93e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  137 KSSTEEEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMKQQLQEKEELISTLQAQLSQTQAEQ 216
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  217 AAQLSSMQQVVRekdarfeTQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEheeslvgRAQVVDLLQQELTAAEQr 296
Cdd:COG4942    100 EAQKEELAELLR-------ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPA-------RREQAEELRADLAELAA- 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  297 nqilsqqlqqIEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMRHLLEQLEQAGQAQAELESRYSALEQ 376
Cdd:COG4942    165 ----------LRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|.
gi 1622909118  377 KHKAEMEEKTS 387
Cdd:COG4942    235 EAAAAAERTPA 245
PLN02939 PLN02939
transferase, transferring glycosyl groups
 634-1001 9.06e-03

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 41.81  E-value: 9.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  634 PNEESSLPAVEKEQASTEHQNRTSEEISLNDAGVELKSTKQDCDKSLSAVPDIGQCHQDeleRLKSQILELelNFHKAQE 713
Cdd:PLN02939    40 RGFSSQQKKKRGKNIAPKQRSSNSKLQSNTDENGQLENTSLRTVMELPQKSTSSDDDHN---RASMQRDEA--IAAIDNE 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  714 IYEKNLDEKakEISNLNqlIEEFKKNADNNSSAFTALSEERDQLLAQV-KELSVVTELRAQVRQLEMNLAEAERQRRFDY 792
Cdd:PLN02939   115 QQTNSKDGE--QLSDFQ--LEDLVGMIQNAEKNILLLNQARLQALEDLeKILTEKEALQGKINILEMRLSETDARIKLAA 190

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  793 ESQtAHHNLLTEQI----HSLSIEAKSKDVKIEVLQNELDDVQlqfsEQSTLIRSLQSQLQNKESEVLEGAERV------ 862
Cdd:PLN02939   191 QEK-IHVEILEEQLeklrNELLIRGATEGLCVHSLSKELDVLK----EENMLLKDDIQFLKAELIEVAETEERVfkleke 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  863 -RHISSKVEELSQALSQKELEIAKMDQLLLEKKRD-VETLQQTIEEKDQQVTEISFSMT-----EKMVQLNEEKFSLGVE 935
Cdd:PLN02939   266 rSLLDASLRELESKFIVAQEDVSKLSPLQYDCWWEkVENLQDLLDRATNQVEKAALVLDqnqdlRDKVDKLEASLKEANV 345

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1622909118  936 IKTLKEQLNLLSRAEEAKKEQVEEDNEVVSGLKQNYDEmspagliSKEELQHEFDLLKKENEQRKR 1001
Cdd:PLN02939   346 SKFSSYKVELLQQKLKLLEERLQASDHEIHSYIQLYQE-------SIKEFQDTLSKLKEESKKRSL 404
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1064-1254 9.24e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1064 QEIEISLKQTISEKEVELEHIRKDLEEKMAAEEQLQALVKEMNQTLQDKTNQIDLLQAEISENQVIIQKLTTSNTDASDG 1143
Cdd:COG4942     40 EKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQ 119

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118 1144 DSVALV--KETVVISPPGTDSGEHWKPELEEKILALEKEKEQLQkKLQEALTSRKAILKKAQEKERHLREELKQQKDDYN 1221
Cdd:COG4942    120 PPLALLlsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA-ALRAELEAERAELEALLAELEEERAALEALKAERQ 198

                          170       180       190
                   ....*....|....*....|....*....|...
gi 1622909118 1222 RLQEQFDEQSKENENIGDQLRQLQIQVRESIDG 1254
Cdd:COG4942    199 KLLARLEKELAELAAELAELQQEAEELEALIAR 231
COG5022 COG5022
Myosin heavy chain [General function prediction only];
33-296 9.91e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.99  E-value: 9.91e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118   33 ELHQESDMEFNNTTQEDVQERLAYAEQLVVELKDIIRQKDvqlQQKDEALQEEKKAADNKiKKLKLHAKAKLTSLNKHIE 112
Cdd:COG5022    856 KAKKRFSLLKKETIYLQSAQRVELAERQLQELKIDVKSIS---SLKLVNLELESEIIELK-KSLSSDLIENLEFKTELIA 931

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  113 EMKaqggtVLLTEPQSEEQLSKhdkssteeEMEVEKIKHKLQEKEEQISTLQAQLTQAQAEQAAQFDKSSTEMKEFVMMK 192
Cdd:COG5022    932 RLK-----KLLNNIDLEEGPSI--------EYVKLPELNKLHEVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFK 998

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1622909118  193 QQLQEKEELISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKLEEH 272
Cdd:COG5022    999 KELAELSKQYGALQESTKQLKELPVEVAELQSASKIISSESTELSILKPLQKLKGLLLLENNQLQARYKALKLRRENSLL 1078

                          250       260
                   ....*....|....*....|....
gi 1622909118  273 EESLVGRAQVVDLLQQELTAAEQR 296
Cdd:COG5022   1079 DDKQLYQLESTENLLKTINVKDLE 1102
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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