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Conserved domains on  [gi|966923583|ref|XP_014979790|]
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dimethylaniline monooxygenase [N-oxide-forming] 4 [Macaca mulatta]

Protein Classification

flavin-binding monooxygenase-like family protein( domain architecture ID 1000557)

flavin-binding monooxygenase-like family protein; such as flavin-containing monooxygenases (FMOs) that catalyze the monooxygenation of a variety of substrates

EC:  1.14.13.-
Gene Ontology:  GO:0004497

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FMO-like super family cl30939
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


The actual alignment was detected with superfamily member pfam00743:

Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 979.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583    2 AKKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   82 MNQEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  162 GIHKFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSEDWGYPFNMMVIRRYYS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKTAK-FIVNDELPNCILCGTITMKTSVMEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKHVFPLNLERATLAIIGLLSLKGSILSATELQARWATRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  401 SQKLMMEATEK-EQLIKRGVIKDTNKDKLDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLVGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 966923583  480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 979.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583    2 AKKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   82 MNQEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  162 GIHKFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSEDWGYPFNMMVIRRYYS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKTAK-FIVNDELPNCILCGTITMKTSVMEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKHVFPLNLERATLAIIGLLSLKGSILSATELQARWATRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  401 SQKLMMEATEK-EQLIKRGVIKDTNKDKLDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLVGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 966923583  480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-395 3.85e-79

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 254.79  E-value: 3.85e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   5 VAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFtesskdgmtRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNQ 84
Cdd:COG2072    9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRD---------NRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  85 EKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRpdfSETGQWDVVTETeGKQNRAvfDAVMVCTGHFLNPHLPleAFPGIH 164
Cdd:COG2072   80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWD---EADGRWTVTTDD-GETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 165 KFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGR---SEDWGYPFNMMVIRRYYS 241
Cdd:COG2072  152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnyDPERGRPANYLGLEAPPA 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 242 FIAqvlpsRFLNWIQERKLNKRFNHEDYGL---SITKGkTAKFIVNDELPNCILCGTITMKTS-VMEFTETSAVFEDGTV 317
Cdd:COG2072  232 LNR-----RDARAWLRRLLRAQVKDPELGLltpDYPPG-CKRPLLSTDYYEALRRGNVELVTGgIERITEDGVVFADGTE 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 318 EEnIDVVIFTTGYTFSFPFFEEPlkslctkKIF---------LYKHVFPLNLERatLAIIGLLSLKG--SILSATELQAR 386
Cdd:COG2072  306 HE-VDVIVWATGFRADLPWLAPL-------DVRgrdgrsgprAYLGVVVPGFPN--LFFLGPNSPSGhsSLTLGAERQAR 375


                 ....*....
gi 966923583 387 WATRVFKGL 395
Cdd:COG2072  376 YIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-407 4.80e-40

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 151.55  E-value: 4.80e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   2 AKKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFT-ESSKDGM----------TRVYKSLVTNVCKEMSCYS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTpKSESDPLsldptrsivhSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  71 DFPF-------HEDYPNFMNQEKFWDYLQEFAEHFDLLKYIQFKTTVCSITkrpdfSETGQWDVVTETEGK-QNRAVFDA 142
Cdd:PLN02172  90 DFPFvprfddeSRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKNSGGfSKDEIFDA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 143 VMVCTGHFLNPHLPleAFPGIHKFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTgtwvlg 222
Cdd:PLN02172 165 VVVCNGHYTEPNVA--HIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASRA------ 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 223 rsedwgypfnmmviRRYYSFIAQVLPSRFLnWIQERklnKRFNHEDyglsitkgktakfivndelpncilcGTItmktsv 302
Cdd:PLN02172 237 --------------SESDTYEKLPVPQNNL-WMHSE---IDTAHED-------------------------GSI------ 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 303 meftetsaVFEDGTVEEnIDVVIFTTGYTFSFPFFE------------EPlkslctkkifLYKHVFPLNLErATLAIIGL 370
Cdd:PLN02172 268 --------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtngymridenrvEP----------LYKHVFPPALA-PGLSFIGL 327

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 966923583 371 LSLkGSILSATELQARWATRVFKGLCKIpPSQKLMME 407
Cdd:PLN02172 328 PAM-GIQFVMFEIQSKWVAAVLSGRVTL-PSEDKMME 362
 
Name Accession Description Interval E-value
FMO-like pfam00743
Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone ...
 2-531 0e+00

Flavin-binding monooxygenase-like; This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.


Pssm-ID: 395602 [Multi-domain]  Cd Length: 531  Bit Score: 979.26  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583    2 AKKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFTESSKDGMTRVYKSLVTNVCKEMSCYSDFPFHEDYPNF 81
Cdd:pfam00743   1 AKKVAVIGAGVSGLASIKCCLEEGLEPTCFERSDDIGGLWRFTENVEEGRASIYKSVITNTSKEMSCFSDFPFPEDYPNF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   82 MNQEKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRPDFSETGQWDVVTETEGKQNRAVFDAVMVCTGHFLNPHLPLEAFP 161
Cdd:pfam00743  81 MHNSKFLEYFRMFAKEFDLLKYIQFKTTVCSVKKRPDFSTSGQWEVVTEHEGKQESAVFDAVMVCTGHHTNPHLPLESFP 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  162 GIHKFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGRSEDWGYPFNMMVIRRYYS 241
Cdd:pfam00743 161 GIEKFKGQYFHSRDYKHPEGFTGKRVLVIGIGNSGGDIAVELSHTAAQVFLSTRRGSWVLSRVSDHGYPWDMLFSTRFTS 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  242 FIAQVLPSRFLNWIQERKLNKRFNHEDYGLSITKGKTAK-FIVNDELPNCILCGTITMKTSVMEFTETSAVFEDGTVEEN 320
Cdd:pfam00743 241 FLRNILPTSISNWLMEKQMNRRFNHENYGLKPKNRALSKePVVNDDLPNRILCGAVKVKPNVKEFTETSAIFEDGTVEED 320

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  321 IDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLYKHVFPLNLERATLAIIGLLSLKGSILSATELQARWATRVFKGLCKIPP 400
Cdd:pfam00743 321 IDVVIFATGYTFAFPFLEESLVKVENNKVSLYKYVFPPNLEKPTLAIIGLIQPLGSIIPTVELQARWATRVFKGLCTLPS 400

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  401 SQKLMMEATEK-EQLIKRGVIKDTNKDKLDYIAYMDDIAACIGTKPSIPLLFLKDPRLAWEVFFGPCTPYQYRLVGPGKW 479
Cdd:pfam00743 401 QSEMMAEINKRqEKKIKRFGDSQSHTIQTDYIDYMDELALFIGAKPNLLSLLLTDPKLALKLFFGPCTPYQYRLVGPGKW 480

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|..
gi 966923583  480 DGARNAILTQWDRTLKPLKTRIVPDSSKPASMShYLKAWGAPVLLASLLLIC 531
Cdd:pfam00743 481 EGARNAILTQWDRILKPLKTRVVEKSSSPASSF-TLKIFGLPVVLVAIFLIL 531
CzcO COG2072
Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ...
 5-395 3.85e-79

Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism];


Pssm-ID: 441675 [Multi-domain]  Cd Length: 414  Bit Score: 254.79  E-value: 3.85e-79
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   5 VAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFtesskdgmtRVYKSLVTNVCKEMSCYSDFPFHEDYPNFMNQ 84
Cdd:COG2072    9 VVVIGAGQAGLAAAYHLRRAGIDFVVLEKADDVGGTWRD---------NRYPGLRLDTPSHLYSLPFFPNWSDDPDFPTG 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  85 EKFWDYLQEFAEHFDLLKYIQFKTTVCSITKRpdfSETGQWDVVTETeGKQNRAvfDAVMVCTGHFLNPHLPleAFPGIH 164
Cdd:COG2072   80 DEILAYLEAYADKFGLRRPIRFGTEVTSARWD---EADGRWTVTTDD-GETLTA--RFVVVATGPLSRPKIP--DIPGLE 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 165 KFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWVLGR---SEDWGYPFNMMVIRRYYS 241
Cdd:COG2072  152 DFAGEQLHSADWRNPVDLAGKRVLVVGTGASAVQIAPELARVAAHVTVFQRTPPWVLPRpnyDPERGRPANYLGLEAPPA 231

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 242 FIAqvlpsRFLNWIQERKLNKRFNHEDYGL---SITKGkTAKFIVNDELPNCILCGTITMKTS-VMEFTETSAVFEDGTV 317
Cdd:COG2072  232 LNR-----RDARAWLRRLLRAQVKDPELGLltpDYPPG-CKRPLLSTDYYEALRRGNVELVTGgIERITEDGVVFADGTE 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 318 EEnIDVVIFTTGYTFSFPFFEEPlkslctkKIF---------LYKHVFPLNLERatLAIIGLLSLKG--SILSATELQAR 386
Cdd:COG2072  306 HE-VDVIVWATGFRADLPWLAPL-------DVRgrdgrsgprAYLGVVVPGFPN--LFFLGPNSPSGhsSLTLGAERQAR 375


                 ....*....
gi 966923583 387 WATRVFKGL 395
Cdd:COG2072  376 YIARLIAHM 384
PLN02172 PLN02172
flavin-containing monooxygenase FMO GS-OX
 2-407 4.80e-40

flavin-containing monooxygenase FMO GS-OX


Pssm-ID: 215116 [Multi-domain]  Cd Length: 461  Bit Score: 151.55  E-value: 4.80e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   2 AKKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGLWKFT-ESSKDGM----------TRVYKSLVTNVCKEMSCYS 70
Cdd:PLN02172  10 SQHVAVIGAGAAGLVAARELRREGHTVVVFEREKQVGGLWVYTpKSESDPLsldptrsivhSSVYESLRTNLPRECMGYR 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  71 DFPF-------HEDYPNFMNQEKFWDYLQEFAEHFDLLKYIQFKTTVCSITkrpdfSETGQWDVVTETEGK-QNRAVFDA 142
Cdd:PLN02172  90 DFPFvprfddeSRDSRRYPSHREVLAYLQDFAREFKIEEMVRFETEVVRVE-----PVDGKWRVQSKNSGGfSKDEIFDA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 143 VMVCTGHFLNPHLPleAFPGIHKFKGQILHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTgtwvlg 222
Cdd:PLN02172 165 VVVCNGHYTEPNVA--HIPGIKSWPGKQIHSHNYRVPDPFKNEVVVVIGNFASGADISRDIAKVAKEVHIASRA------ 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 223 rsedwgypfnmmviRRYYSFIAQVLPSRFLnWIQERklnKRFNHEDyglsitkgktakfivndelpncilcGTItmktsv 302
Cdd:PLN02172 237 --------------SESDTYEKLPVPQNNL-WMHSE---IDTAHED-------------------------GSI------ 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583 303 meftetsaVFEDGTVEEnIDVVIFTTGYTFSFPFFE------------EPlkslctkkifLYKHVFPLNLErATLAIIGL 370
Cdd:PLN02172 268 --------VFKNGKVVY-ADTIVHCTGYKYHFPFLEtngymridenrvEP----------LYKHVFPPALA-PGLSFIGL 327

                        410       420       430
                 ....*....|....*....|....*....|....*..
gi 966923583 371 LSLkGSILSATELQARWATRVFKGLCKIpPSQKLMME 407
Cdd:PLN02172 328 PAM-GIQFVMFEIQSKWVAAVLSGRVTL-PSEDKMME 362
Pyr_redox_3 pfam13738
Pyridine nucleotide-disulphide oxidoreductase;
72-352 3.30e-17

Pyridine nucleotide-disulphide oxidoreductase;


Pssm-ID: 404603 [Multi-domain]  Cd Length: 296  Bit Score: 82.27  E-value: 3.30e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   72 FPFHEDYPNfmnQEKFWDYLQEFAEHFDLLkyIQFKTTVCSITKrpdfsETGQWDVVTetegkqNRAVFDA--VMVCTGH 149
Cdd:pfam13738  65 FTFNREHPS---GNEYAEYLRRVADHFELP--INLFEEVTSVKK-----EDDGFVVTT------SKGTYQAryVIIATGE 128

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  150 FLNPHLPleAFPGIHKfkgqilHSQEYKIPEGFQGKRILVIGLGNTGGDIAVELSRTAAQVLLSTRTGTWvlgrsEDWGY 229
Cdd:pfam13738 129 FDFPNKL--GVPELPK------HYSYVKDFHPYAGQKVVVIGGYNSAVDAALELVRKGARVTVLYRGSEW-----EDRDS 195

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  230 PfnmmvirryysfiaqvlPSRFLN-WIQERklnkrfnhedyglsitkgktakfivndeLPNCILCGTITM--KTSVMEFT 306
Cdd:pfam13738 196 D-----------------PSYSLSpDTLNR----------------------------LEELVKNGKIKAhfNAEVKEIT 230

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 966923583  307 ETSAV----FEDGTVEENIDVVIFTTGYTFSFPFFEEPLKSLCTKKIFLY 352
Cdd:pfam13738 231 EVDVSykvhTEDGRKVTSNDDPILATGYHPDLSFLKKGLFELDEDGRPVL 280
Lys_Orn_oxgnase pfam13434
L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold ...
 81-215 2.89e-08

L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase; This is a family of Rossmann fold oxidoreductases that catalyze NADPH-dependent hydroxylation and are involved in siderophore biosynthesis. This family includes L-ornithine 5-monooxygenase, which catalyzes the hydroxylation of L-ornithine at the N5 position, and L-lysine 6-monooxygenase, which catalyzes the hydroxylation of lysine at the N6 position (EC:1.14.13.59).


Pssm-ID: 433204 [Multi-domain]  Cd Length: 338  Bit Score: 55.67  E-value: 2.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   81 FMNQEKFW-------DYLQEFAEHFDllKYIQFKTTVCSITKRPDfSETGQWDVVTETEGKQNRAVF-DAVMVCTGhfLN 152
Cdd:pfam13434  84 FYNLETFFpsrrefnDYLQWAASHLP--NRLRFGQEVESVEPDAE-RGEPLLRVRVRDADGEETTFLaRNLVLGTG--GE 158

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 966923583  153 PHLPlEAFPGihkfKGQILHSQEY--KIPEGFQGKRILVIGLGNTGGDIAVELSRT--AAQVLLSTR 215
Cdd:pfam13434 159 PYIP-ECARG----GERVFHSSEYleRIDRLAAKKRIAVVGSGQSAAEIFRDLLRRgpAYELTWVTR 220
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
4-215 6.68e-06

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 48.19  E-value: 6.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   4 KVAVIGAGVSGISSIKCCVDEDLEPTCFERsDDIGG-LWKFTEsskdgmtrvykslVTNvckemscYSDFPFHEDYPNFM 82
Cdd:COG0492    2 DVVIIGAGPAGLTAAIYAARAGLKTLVIEG-GEPGGqLATTKE-------------IEN-------YPGFPEGISGPELA 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  83 nqekfwDYLQEFAEHFDllkyIQFKTT-VCSITKrpdfsETGQWDVVTEtEGKQNRAvfDAVMVCTGHFLNPhLPLeafP 161
Cdd:COG0492   61 ------ERLREQAERFG----AEILLEeVTSVDK-----DDGPFRVTTD-DGTEYEA--KAVIIATGAGPRK-LGL---P 118

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 966923583 162 GIHKFKGQILHsqeYKIP-EGFQ--GKRILVIGLGNTGGDIAVELSRTAAQVLLSTR 215
Cdd:COG0492  119 GEEEFEGRGVS---YCATcDGFFfrGKDVVVVGGGDSALEEALYLTKFASKVTLIHR 172
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 3-207 4.07e-04

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 42.84  E-value: 4.07e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   3 KKVAVIGAGVSGISsikcCVDEdL-----EPTCFERSDDIGGLWKFtesskdGMtrvykslvtnvckemscysdfpfhed 77
Cdd:PRK12810 144 KKVAVVGSGPAGLA----AADQ-LaraghKVTVFERADRIGGLLRY------GI-------------------------- 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  78 yPNF-MnqEKfwdylqEFAEH-FDLLKY--IQFKTTVcsitkrpdfsETGQwDVVTEtegkQNRAVFDAVMVCTGHFLNP 153
Cdd:PRK12810 187 -PDFkL--EK------EVIDRrIELMEAegIEFRTNV----------EVGK-DITAE----ELLAEYDAVFLGTGAYKPR 242

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 966923583 154 HLPL--EAFPGIHK---FKGQILHSQEYKIPEGF---QGKRILVIGlgntGGDIAVELSRTA 207
Cdd:PRK12810 243 DLGIpgRDLDGVHFamdFLIQNTRRVLGDETEPFisaKGKHVVVIG----GGDTGMDCVGTA 300
NAD_binding_9 pfam13454
FAD-NAD(P)-binding;
6-150 5.37e-04

FAD-NAD(P)-binding;


Pssm-ID: 433222 [Multi-domain]  Cd Length: 155  Bit Score: 40.72  E-value: 5.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583    6 AVIGAGVSGISS----IKCCVDEDLEPTCFERSDD-IGGLWkFTESSKDGMTRVYKSlvtnvckEMSCYSDFPFH----- 75
Cdd:pfam13454   1 AIVGGGPSGLALlerlLARAPKRPLEITLFDPSPPgAGGVY-RTDQSPEHLLNVPAS-------RMSLFPDDPPHflewl 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   76 ------EDYPNFMNQEK-----FWDYLQEFAEHF--DLLKYIQF---KTTVCSITKRPDfsetGQWdvVTETEGKQNRAv 139
Cdd:pfam13454  73 rargalDEAPGLDPDDFppralYGRYLRDRFEEAlaRAPAGVTVrvhRARVTDLRPRGD----GYR--VLLADGRTLAA- 145

                         170
                  ....*....|.
gi 966923583  140 fDAVMVCTGHF 150
Cdd:pfam13454 146 -DAVVLATGHG 155
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 3-207 4.68e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 39.73  E-value: 4.68e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583   3 KKVAVIGAGVSGISsikcCVDeDL-----EPTCFERSDDIGGLwkftesskdgMTrvykslvtnvckemscysdfpfhed 77
Cdd:COG0493  122 KKVAVVGSGPAGLA----AAY-QLaraghEVTVFEALDKPGGL----------LR------------------------- 161

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 966923583  78 Y--PNF-MnqEKfwDYLQefAEHfDLLK--YIQFKTTVcSITKrpDFSetgqwdvvteteGKQNRAVFDAVMVCTG---- 148
Cdd:COG0493  162 YgiPEFrL--PK--DVLD--REI-ELIEalGVEFRTNV-EVGK--DIT------------LDELLEEFDAVFLATGagkp 219

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 966923583 149 HFLNphLPLEAFPGIHK---F-KGQILHSQEYKIPegFQGKRILVIGLGNTGGDIAvelsRTA 207
Cdd:COG0493  220 RDLG--IPGEDLKGVHSamdFlTAVNLGEAPDTIL--AVGKRVVVIGGGNTAMDCA----RTA 274
HemY COG1232
Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen ...
 3-40 5.90e-03

Protoporphyrinogen oxidase HemY/PPOX [Coenzyme transport and metabolism]; Protoporphyrinogen oxidase HemY/PPOX is part of the Pathway/BioSystem: Heme biosynthesis


Pssm-ID: 440845 [Multi-domain]  Cd Length: 443  Bit Score: 39.43  E-value: 5.90e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 966923583   3 KKVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGL 40
Cdd:COG1232    2 KRVAVIGGGIAGLTAAYRLAKAGHEVTVLEASDRVGGL 39
PRK07233 PRK07233
hypothetical protein; Provisional
 4-40 8.02e-03

hypothetical protein; Provisional


Pssm-ID: 235977 [Multi-domain]  Cd Length: 434  Bit Score: 38.71  E-value: 8.02e-03
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 966923583   4 KVAVIGAGVSGISSIKCCVDEDLEPTCFERSDDIGGL 40
Cdd:PRK07233   1 KIAIVGGGIAGLAAAYRLAKRGHEVTVFEADDQLGGL 37
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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