|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1810-2136 |
9.55e-93 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
:
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 304.88 E-value: 9.55e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1810 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKvappclaqSAAPAKVPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPP 1889
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPK--------TDAPAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1890 ARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQKPA 1961
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1962 R-----RGPPPLARAVPEpgPRGRAGTEAGPGARGGRLGLVRVAsALSSGSESSDRSGFRRQLTFIKESPG-LRRRRSEL 2035
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPE--PRSESASKGLRSLPGKRLDLVRMS-SARSSGSESDRSGFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2036 SSAESAASAPQGTSPRRGRPALPAVFLCSSRCEELRAAPRQAPA--RQRPPAARPGPGERPARRTSSESPSRLPVRAPAA 2113
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNpnSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|...
gi 967490223 2114 RPETVKRYASLPHISVARRPDGT 2136
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGSS 331
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
381-455 |
1.35e-35 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
:
Pssm-ID: 465870 Cd Length: 74 Bit Score: 130.36 E-value: 1.35e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967490223 381 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAPEgGGASGVPVPIEPQICQATCAVMKLSFDEEYRRAM 455
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPE-GDSNPMPSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
30-81 |
1.09e-25 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
:
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.60 E-value: 1.09e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 967490223 30 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 81
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 super family |
cl25003 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
721-968 |
2.57e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
The actual alignment was detected with superfamily member pfam16629:
Pssm-ID: 435476 Cd Length: 293 Bit Score: 93.88 E-value: 2.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 721 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKHRPPAAEATskKPlpplRHLDGLAQDYASDSG 800
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRN--KQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 801 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDASGEAAVAAKAKA----------- 869
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 870 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 939
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 967490223 940 KAAHASLSNDSLNSGSASDGYCPREHMLP 968
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
148-229 |
4.29e-20 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
:
Pssm-ID: 463275 Cd Length: 82 Bit Score: 86.54 E-value: 4.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 148 SRATIRLLEELDRERCLLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFG 227
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 967490223 228 TS 229
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
1538-1992 |
1.47e-10 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.27 E-value: 1.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1538 SDEEPPAAAPTPTHRRTSAIPRALTRERLQGR-------------KEAPAPSKAAPSAPPPTRAQPSLiadETPPCYSLS 1604
Cdd:PHA03247 2501 GGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSV---PPPRPAPRP 2577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1605 SSASSLSEPEPPEPPSVSPRGQEPAVTKDPgPRGGRDSSPSPRAAeellqrcissalPRRRPPVSGlRRRKPRATRLDER 1684
Cdd:PHA03247 2578 SEPAVTSRARRPDAPPQSARPRAPVDDRGD-PRGPAPPSPLPPDT------------HAPDPPPPS-PSPAANEPDPHPP 2643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1685 PAEGSREHGEEAAGSDRASDLDSVEWRAIQEGANSIVT-WLHQAAAATREassesdsilsfvsglSVGSTLQPPKHRKGR 1763
Cdd:PHA03247 2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQrPRRRAARPTVG---------------SLTSLADPPPPPPTP 2708
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1764 QAGGEMGSARRPEKRGAASAKTS--GSPRSPAGPEKPRGTqkTTPGVPA-VLRGRTVIYVPSPAPRAQPKGTPGPRATPR 1840
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQAspALPAAPAPPAVPAGP--ATPGGPArPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1841 KVAPPCLAQSAAP-----AKVPSPGQQRSRSL---HRPGKTSELGTLSQPPRSATPPARLAKTPSS------------SS 1900
Cdd:PHA03247 2787 AVASLSESRESLPspwdpADPPAAVLAPAAALppaASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvrrRP 2866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1901 SQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGR 1980
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
490
....*....|..
gi 967490223 1981 AGTEAGPGARGG 1992
Cdd:PHA03247 2947 TDPAGAGEPSGA 2958
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
639-678 |
1.24e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.24e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 967490223 639 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 678
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| PRK12323 super family |
cl46901 |
DNA polymerase III subunit gamma/tau; |
1373-1599 |
4.86e-04 |
|
DNA polymerase III subunit gamma/tau;
The actual alignment was detected with superfamily member PRK12323:
Pssm-ID: 481241 [Multi-domain] Cd Length: 700 Bit Score: 45.25 E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1373 AAVPARLRKVASALVPGRRALPVPVYMLVPAPARAQEDDsctdsaegtpvnfSSAASLSDETLQGPPRDQPGGPEGRQRP 1452
Cdd:PRK12323 384 QPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-------------PARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1453 TGRPTSArqavghrhKAGGAGRSVEQARGTGkNRAGLELPLGRPPSAPADKDDSKPGRTRGDGALQSLCLttpteeavyc 1532
Cdd:PRK12323 451 APAPAAA--------PAAAARPAAAGPRPVA-AAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAP---------- 511
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967490223 1533 fygNDSDEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPP 1599
Cdd:PRK12323 512 ---AQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
|
|
| PRK07764 super family |
cl35613 |
DNA polymerase III subunits gamma and tau; Validated |
2072-2321 |
1.08e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
The actual alignment was detected with superfamily member PRK07764:
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.21 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2072 AAPRQAPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPETVKRYASLPHISVARRPDGTVPAAPAPADAARRSS 2151
Cdd:PRK07764 419 AAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2152 DGEPRSLPR-VAAPGTTWRRIRdEDVPHILRSTLP-----ATALPLRGST------------------------------ 2195
Cdd:PRK07764 499 APAAPAGADdAATLRERWPEIL-AAVPKRSRKTWAillpeATVLGVRGDTlvlgfstgglarrfaspgnaevlvtalaee 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2196 ------------PEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLESREPPGAPASGqlsllgsdvdGPSLAKAPIS 2263
Cdd:PRK07764 578 lggdwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA----------EASAAPAPGV 647
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967490223 2264 APFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSP---MVVAATTDSAAEKAPATSSA 2321
Cdd:PRK07764 648 AAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPapaAPAAPAGAAPAQPAPAPAAT 708
|
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1284-1305 |
2.45e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
:
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.45e-03
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
549-586 |
9.47e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.47e-03
10 20 30
....*....|....*....|....*....|....*...
gi 967490223 549 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 586
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
685-720 |
9.95e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
:
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.95e-03
10 20 30
....*....|....*....|....*....|....*.
gi 967490223 685 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 720
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1810-2136 |
9.55e-93 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 304.88 E-value: 9.55e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1810 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKvappclaqSAAPAKVPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPP 1889
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPK--------TDAPAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1890 ARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQKPA 1961
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1962 R-----RGPPPLARAVPEpgPRGRAGTEAGPGARGGRLGLVRVAsALSSGSESSDRSGFRRQLTFIKESPG-LRRRRSEL 2035
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPE--PRSESASKGLRSLPGKRLDLVRMS-SARSSGSESDRSGFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2036 SSAESAASAPQGTSPRRGRPALPAVFLCSSRCEELRAAPRQAPA--RQRPPAARPGPGERPARRTSSESPSRLPVRAPAA 2113
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNpnSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|...
gi 967490223 2114 RPETVKRYASLPHISVARRPDGT 2136
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGSS 331
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
381-455 |
1.35e-35 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
Pssm-ID: 465870 Cd Length: 74 Bit Score: 130.36 E-value: 1.35e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967490223 381 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAPEgGGASGVPVPIEPQICQATCAVMKLSFDEEYRRAM 455
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPE-GDSNPMPSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
30-81 |
1.09e-25 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.60 E-value: 1.09e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 967490223 30 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 81
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 |
pfam16629 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
721-968 |
2.57e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
Pssm-ID: 435476 Cd Length: 293 Bit Score: 93.88 E-value: 2.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 721 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKHRPPAAEATskKPlpplRHLDGLAQDYASDSG 800
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRN--KQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 801 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDASGEAAVAAKAKA----------- 869
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 870 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 939
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 967490223 940 KAAHASLSNDSLNSGSASDGYCPREHMLP 968
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
148-229 |
4.29e-20 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
Pssm-ID: 463275 Cd Length: 82 Bit Score: 86.54 E-value: 4.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 148 SRATIRLLEELDRERCLLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFG 227
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 967490223 228 TS 229
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1538-1992 |
1.47e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.27 E-value: 1.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1538 SDEEPPAAAPTPTHRRTSAIPRALTRERLQGR-------------KEAPAPSKAAPSAPPPTRAQPSLiadETPPCYSLS 1604
Cdd:PHA03247 2501 GGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSV---PPPRPAPRP 2577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1605 SSASSLSEPEPPEPPSVSPRGQEPAVTKDPgPRGGRDSSPSPRAAeellqrcissalPRRRPPVSGlRRRKPRATRLDER 1684
Cdd:PHA03247 2578 SEPAVTSRARRPDAPPQSARPRAPVDDRGD-PRGPAPPSPLPPDT------------HAPDPPPPS-PSPAANEPDPHPP 2643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1685 PAEGSREHGEEAAGSDRASDLDSVEWRAIQEGANSIVT-WLHQAAAATREassesdsilsfvsglSVGSTLQPPKHRKGR 1763
Cdd:PHA03247 2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQrPRRRAARPTVG---------------SLTSLADPPPPPPTP 2708
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1764 QAGGEMGSARRPEKRGAASAKTS--GSPRSPAGPEKPRGTqkTTPGVPA-VLRGRTVIYVPSPAPRAQPKGTPGPRATPR 1840
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQAspALPAAPAPPAVPAGP--ATPGGPArPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1841 KVAPPCLAQSAAP-----AKVPSPGQQRSRSL---HRPGKTSELGTLSQPPRSATPPARLAKTPSS------------SS 1900
Cdd:PHA03247 2787 AVASLSESRESLPspwdpADPPAAVLAPAAALppaASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvrrRP 2866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1901 SQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGR 1980
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
490
....*....|..
gi 967490223 1981 AGTEAGPGARGG 1992
Cdd:PHA03247 2947 TDPAGAGEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1772-2325 |
1.59e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.72 E-value: 1.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1772 ARRPEKRGAASAKTSGSPRSPAGPEKPRGTQKT-----TPGVPAVLRGRTVIY-----------------VPSPAPRAQP 1829
Cdd:PHA03247 2486 ARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpdePVGEPVHPRMLTWIRgleelasddagdpppplPPAAPPAAPD 2565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1830 KGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSrslhrPGKTSELGTLSQPPrSATPPArlaktpsssssqTSPASQP 1909
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRA-----PVDDRGDPRGPAPP-SPLPPD------------THAPDPP 2627
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1910 LPRKRPLVTQAAGPLPGPGASPV-PKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAV--------------PE 1974
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPPErPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgsltsladpppppPT 2707
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1975 PGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGfrrQLTFIKESPGLRRRRSELSSAESAASAPQGTSPRRGR 2054
Cdd:PHA03247 2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG---PATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT 2784
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2055 PALPAVFLCSSRCEELRAAPRQAPARQRPPAARPGPGERPARrTSSESPSRLPVrAPAARPETVKRYASLPHiSVArrPD 2134
Cdd:PHA03247 2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG-PLPPPTSAQPT-APPPPPGPPPPSLPLGG-SVA--PG 2859
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2135 GTVPaapapadaaRRSSDGEPRSLPrvAAPgttwrrirdedvPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQ 2214
Cdd:PHA03247 2860 GDVR---------RRPPSRSPAAKP--AAP------------ARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPP 2916
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2215 TEEVAAPKTNSSTSPSLESREPPGAPASGQLSLLGSDVDGPSlAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPP 2294
Cdd:PHA03247 2917 PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA-VPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPP 2995
|
570 580 590
....*....|....*....|....*....|.
gi 967490223 2295 FNYVPSPMVVAATTDSAAEKAPATSSATLLE 2325
Cdd:PHA03247 2996 LTGHSLSRVSSWASSLALHEETDPPPVSLKQ 3026
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
639-678 |
1.24e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.24e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 967490223 639 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 678
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| ARM |
smart00185 |
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ... |
638-678 |
1.88e-06 |
|
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.
Pssm-ID: 214547 [Multi-domain] Cd Length: 41 Bit Score: 46.27 E-value: 1.88e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 967490223 638 REDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 678
Cdd:smart00185 1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1373-1599 |
4.86e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.25 E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1373 AAVPARLRKVASALVPGRRALPVPVYMLVPAPARAQEDDsctdsaegtpvnfSSAASLSDETLQGPPRDQPGGPEGRQRP 1452
Cdd:PRK12323 384 QPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-------------PARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1453 TGRPTSArqavghrhKAGGAGRSVEQARGTGkNRAGLELPLGRPPSAPADKDDSKPGRTRGDGALQSLCLttpteeavyc 1532
Cdd:PRK12323 451 APAPAAA--------PAAAARPAAAGPRPVA-AAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAP---------- 511
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967490223 1533 fygNDSDEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPP 1599
Cdd:PRK12323 512 ---AQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2072-2321 |
1.08e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.21 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2072 AAPRQAPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPETVKRYASLPHISVARRPDGTVPAAPAPADAARRSS 2151
Cdd:PRK07764 419 AAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2152 DGEPRSLPR-VAAPGTTWRRIRdEDVPHILRSTLP-----ATALPLRGST------------------------------ 2195
Cdd:PRK07764 499 APAAPAGADdAATLRERWPEIL-AAVPKRSRKTWAillpeATVLGVRGDTlvlgfstgglarrfaspgnaevlvtalaee 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2196 ------------PEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLESREPPGAPASGqlsllgsdvdGPSLAKAPIS 2263
Cdd:PRK07764 578 lggdwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA----------EASAAPAPGV 647
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967490223 2264 APFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSP---MVVAATTDSAAEKAPATSSA 2321
Cdd:PRK07764 648 AAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPapaAPAAPAGAAPAQPAPAPAAT 708
|
|
| SAMP |
pfam05924 |
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1645-1666 |
1.62e-03 |
|
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). This motif binds axin.
Pssm-ID: 461782 Cd Length: 22 Bit Score: 37.57 E-value: 1.62e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1410-1432 |
2.33e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.33e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1284-1305 |
2.45e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.45e-03
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
549-586 |
9.47e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.47e-03
10 20 30
....*....|....*....|....*....|....*...
gi 967490223 549 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 586
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
685-720 |
9.95e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.95e-03
10 20 30
....*....|....*....|....*....|....*.
gi 967490223 685 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 720
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| APC_basic |
pfam05956 |
APC basic domain; This region of the APC family of proteins is known as the basic domain. It ... |
1810-2136 |
9.55e-93 |
|
APC basic domain; This region of the APC family of proteins is known as the basic domain. It contains a high proportion of positively charged amino acids and interacts with microtubules.
Pssm-ID: 428690 [Multi-domain] Cd Length: 336 Bit Score: 304.88 E-value: 9.55e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1810 AVLRGRTVIYVPSpAPRAQPKGTPGPRATPRKvappclaqSAAPAKVPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPP 1889
Cdd:pfam05956 1 VVFRGRTVIYMPG-VKESQPSTSPPPKKTPPK--------TDAPAKNPNLGQQRSRSLHRLGKPSELADLSPPKRSATPP 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1890 ARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGAS------PVPKTPARTLLAKQ--HKTQRSPVRIPFMQKPA 1961
Cdd:pfam05956 72 ARISKAPSSGSSRDSTPSRPPQKKLTSPSQSPGRLPGSGGRnklsplPKTKSPARASTKKSgsHKTQKSPVRIPFMQTPT 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1962 R-----RGPPPLARAVPEpgPRGRAGTEAGPGARGGRLGLVRVAsALSSGSESSDRSGFRRQLTFIKESPG-LRRRRSEL 2035
Cdd:pfam05956 152 KqtglpRNPSPLVTNQPE--PRSESASKGLRSLPGKRLDLVRMS-SARSSGSESDRSGFLRQLTFIKESPSlLLRRRLEL 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2036 SSAESAASAPQGTSPRRGRPALPAVFLCSSRCEELRAAPRQAPA--RQRPPAARPGPGERPARRTSSESPSRLPVRAPAA 2113
Cdd:pfam05956 229 SASESLSPSSQPASPRRSRPGLPAVFLCSSRCQELKGWRKQPPNpnSRAEPSDRPLTRRRPPRRTSSESPSRLPVRNGTW 308
|
330 340
....*....|....*....|...
gi 967490223 2114 RPETVKRYASLPHISVARRPDGT 2136
Cdd:pfam05956 309 KRETFKRYSSLPHINVWRRTGSS 331
|
|
| APC_rep |
pfam18797 |
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo ... |
381-455 |
1.35e-35 |
|
Adenomatous polyposis coli (APC) repeat; Adenomatous polyposis coli contains an armadillo repeat and uses its highly conserved surface groove to recognize the APC-binding region (ABR) of Asef. This entry represents a single repeat unit of the Armadillo region.
Pssm-ID: 465870 Cd Length: 74 Bit Score: 130.36 E-value: 1.35e-35
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 967490223 381 SQPDQGLARKEMRVLHVLEQIRAYCETCWDWLQARDGAPEgGGASGVPVPIEPQICQATCAVMKLSFDEEYRRAM 455
Cdd:pfam18797 1 SQPDDKRGRREMRVLHLLEQIRAYCETCWDWQESHSRGPE-GDSNPMPSPIEHQICPAICALMKLSFDEEHRHAM 74
|
|
| APC_N_CC |
pfam16689 |
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil ... |
30-81 |
1.09e-25 |
|
Coiled-coil N-terminus of APC, dimerization domain; APC_N_CC is the N-terminal, coiled-coil dimerization domain of the adenomatosis polyposis coli (APC) tumour-repressor proteins. It plays a key role in the regulation of cellular levels of the oncogene product beta-catenin. Coiled-coil regions are binding repeats that in this case bind to the armadillo repeat region of beta-catenin.
Pssm-ID: 435517 Cd Length: 52 Bit Score: 101.60 E-value: 1.09e-25
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 967490223 30 APYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKL 81
Cdd:pfam16689 1 ASYDQLLRQVEALKLENTTLRQELRDNSSHLSKLETEASNMKEVLKHLQGSI 52
|
|
| Arm_APC_u3 |
pfam16629 |
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately ... |
721-968 |
2.57e-20 |
|
Armadillo-associated region on APC; Arm_APC_u3 is a semi-unstructured region lying immediately downstream of the armadillo fold before the beta-catenin binding motifs, APC_crr, pfam05923, on APC or adenomatous polyposis coli proteins in higher eukaryotes. The function is not known.
Pssm-ID: 435476 Cd Length: 293 Bit Score: 93.88 E-value: 2.57e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 721 HRPAKHQAAaTAVSPGSCVPSLYVRKQRALEAELDARHLAQALEHLEKHRPPAAEATskKPlpplRHLDGLAQDYASDSG 800
Cdd:pfam16629 1 NRPAKYKDA-NIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSPKASHRN--KQ----RHKQNVYSEYVLDSG 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 801 CFDDDDAPSSlaaaaaTGEPASPAALSLFLGSPFLQGQAlARTPPTRRGGKEAEKDASGEAAVAAKAKA----------- 869
Cdd:pfam16629 74 RHDDSVCRSD------NFNTGNVTVLSPYLNTTVLPSSS-SRDSRGNAESSRSEKDRSLDRERGAGLSNfhpatensgns 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 870 ------KLALAVARIDQLVEDISALHTSSDDSFSLSSGDP---GQEAPREGRAQSCSPCRGPEG-GRREAGSRAHPLLRL 939
Cdd:pfam16629 147 skrigmQISTTAAQIAKVMEEVSSMHISQEDRSSGSTSDMhcmQDDRNSIRRSSTAHPHSNVYSfNKSESSNRPCPMPYM 226
|
250 260
....*....|....*....|....*....
gi 967490223 940 KAAHASLSNDSLNSGSASDGYCPREHMLP 968
Cdd:pfam16629 227 KMEYKRASNDSLNSVSSSDGYGKRGQMKP 255
|
|
| Suppressor_APC |
pfam11414 |
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has ... |
148-229 |
4.29e-20 |
|
Adenomatous polyposis coli tumour suppressor protein; The tumour suppressor protein, APC, has a nuclear export activity as well as many different intracellular functions. The structure consists of three alpha-helices forming two separate antiparallel coiled coils.
Pssm-ID: 463275 Cd Length: 82 Bit Score: 86.54 E-value: 4.29e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 148 SRATIRLLEELDRERCLLLNEIEKEEKEKLWYYSQLQGLSKRLDELPHVETQFSMQMDLIRQQLEFEAQHIRSLMEERFG 227
Cdd:pfam11414 1 DYNMLKRMKQLEQEKDVLLQGLEMVERARDWYQQQLQEVQERQKYLGANGTYFDYGSDAQQERLEFLLARIQEVNRCLGG 80
|
..
gi 967490223 228 TS 229
Cdd:pfam11414 81 LI 82
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1538-1992 |
1.47e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 67.27 E-value: 1.47e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1538 SDEEPPAAAPTPTHRRTSAIPRALTRERLQGR-------------KEAPAPSKAAPSAPPPTRAQPSLiadETPPCYSLS 1604
Cdd:PHA03247 2501 GGPPDPDAPPAPSRLAPAILPDEPVGEPVHPRmltwirgleelasDDAGDPPPPLPPAAPPAAPDRSV---PPPRPAPRP 2577
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1605 SSASSLSEPEPPEPPSVSPRGQEPAVTKDPgPRGGRDSSPSPRAAeellqrcissalPRRRPPVSGlRRRKPRATRLDER 1684
Cdd:PHA03247 2578 SEPAVTSRARRPDAPPQSARPRAPVDDRGD-PRGPAPPSPLPPDT------------HAPDPPPPS-PSPAANEPDPHPP 2643
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1685 PAEGSREHGEEAAGSDRASDLDSVEWRAIQEGANSIVT-WLHQAAAATREassesdsilsfvsglSVGSTLQPPKHRKGR 1763
Cdd:PHA03247 2644 PTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQrPRRRAARPTVG---------------SLTSLADPPPPPPTP 2708
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1764 QAGGEMGSARRPEKRGAASAKTS--GSPRSPAGPEKPRGTqkTTPGVPA-VLRGRTVIYVPSPAPRAQPKGTPGPRATPR 1840
Cdd:PHA03247 2709 EPAPHALVSATPLPPGPAAARQAspALPAAPAPPAVPAGP--ATPGGPArPARPPTTAGPPAPAPPAAPAAGPPRRLTRP 2786
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1841 KVAPPCLAQSAAP-----AKVPSPGQQRSRSL---HRPGKTSELGTLSQPPRSATPPARLAKTPSS------------SS 1900
Cdd:PHA03247 2787 AVASLSESRESLPspwdpADPPAAVLAPAAALppaASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLggsvapggdvrrRP 2866
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1901 SQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGR 1980
Cdd:PHA03247 2867 PSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT 2946
|
490
....*....|..
gi 967490223 1981 AGTEAGPGARGG 1992
Cdd:PHA03247 2947 TDPAGAGEPSGA 2958
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1438-1973 |
7.60e-09 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 61.49 E-value: 7.60e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1438 PPRDQPGGPEgRQRPTGR--PTSARQAVGHRHKAGGAGRSVEQARGTGKNRAGlelPLGRPPSAPADKDDSKPGRTRGDG 1515
Cdd:PHA03247 2556 PPAAPPAAPD-RSVPPPRpaPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGD---PRGPAPPSPLPPDTHAPDPPPPSP 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1516 ALQslclttpteeavycfyGNDSDEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSL--- 1592
Cdd:PHA03247 2632 SPA----------------ANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVgsl 2695
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1593 --IADETPPCYSLSSSASSLSEPEPPEPPSVSPRGQEPAVTKDPGPRGGRDSSPSPRAAEELLQRCISSALPRRRPPVSG 1670
Cdd:PHA03247 2696 tsLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAP 2775
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1671 LRRRKPRATRlderPAEGSREHGEEAAGSDRASdldsvewraiqegANSIVTWLHQAAAATREASSesdsilsfvsglsv 1750
Cdd:PHA03247 2776 AAGPPRRLTR----PAVASLSESRESLPSPWDP-------------ADPPAAVLAPAAALPPAASP-------------- 2824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1751 GSTLQPPkhrkgrqaggemgsarrPEKRGAASAKTSGSPRSPAGPEKprgtqKTTPGVPAVLRGrtviyvPSPAPRAQPK 1830
Cdd:PHA03247 2825 AGPLPPP-----------------TSAQPTAPPPPPGPPPPSLPLGG-----SVAPGGDVRRRP------PSRSPAAKPA 2876
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1831 GTPGPRAtpRKVAPPCLAQSAAPAKVPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPParlaktpsssssqtspasQPL 1910
Cdd:PHA03247 2877 APARPPV--RRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP------------------PPP 2936
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967490223 1911 PRKRPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKT---QRSPVRIPFMQKPARRGPPPLARAVP 1973
Cdd:PHA03247 2937 PRPQPPLAPTTDPAGAGEPSGAVPQPWLGALVPGRVAvprFRVPQPAPSREAPASSTPPLTGHSLS 3002
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1772-2325 |
1.59e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.72 E-value: 1.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1772 ARRPEKRGAASAKTSGSPRSPAGPEKPRGTQKT-----TPGVPAVLRGRTVIY-----------------VPSPAPRAQP 1829
Cdd:PHA03247 2486 ARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpdePVGEPVHPRMLTWIRgleelasddagdpppplPPAAPPAAPD 2565
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1830 KGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSrslhrPGKTSELGTLSQPPrSATPPArlaktpsssssqTSPASQP 1909
Cdd:PHA03247 2566 RSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRA-----PVDDRGDPRGPAPP-SPLPPD------------THAPDPP 2627
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1910 LPRKRPLVTQAAGPLPGPGASPV-PKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAV--------------PE 1974
Cdd:PHA03247 2628 PPSPSPAANEPDPHPPPTVPPPErPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgsltsladpppppPT 2707
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1975 PGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGfrrQLTFIKESPGLRRRRSELSSAESAASAPQGTSPRRGR 2054
Cdd:PHA03247 2708 PEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG---PATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT 2784
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2055 PALPAVFLCSSRCEELRAAPRQAPARQRPPAARPGPGERPARrTSSESPSRLPVrAPAARPETVKRYASLPHiSVArrPD 2134
Cdd:PHA03247 2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAG-PLPPPTSAQPT-APPPPPGPPPPSLPLGG-SVA--PG 2859
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2135 GTVPaapapadaaRRSSDGEPRSLPrvAAPgttwrrirdedvPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQ 2214
Cdd:PHA03247 2860 GDVR---------RRPPSRSPAAKP--AAP------------ARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPP 2916
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2215 TEEVAAPKTNSSTSPSLESREPPGAPASGQLSLLGSDVDGPSlAKAPISAPFVHEGLGVAVGGFPASRHGSPSRSARVPP 2294
Cdd:PHA03247 2917 PQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGA-VPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTPP 2995
|
570 580 590
....*....|....*....|....*....|.
gi 967490223 2295 FNYVPSPMVVAATTDSAAEKAPATSSATLLE 2325
Cdd:PHA03247 2996 LTGHSLSRVSSWASSLALHEETDPPPVSLKQ 3026
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1756-2243 |
2.30e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 59.95 E-value: 2.30e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1756 PPKHRKGRQAGGEMGS-ARRPEkrgaaSAKTSGSPRSPAGP-EKPRGTQKTTPGVPAVLRGRTViyVPSPAPRAQPKGTP 1833
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSrARRPD-----APPQSARPRAPVDDrGDPRGPAPPSPLPPDTHAPDPP--PPSPSPAANEPDPH 2641
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1834 GPRATPrkvAPPCLAQSAAPAKVPSPgqQRSRSLHRPGKTSelgtlsQPPRSATPPARLAKTPSSSSSQTSPASQPLPRK 1913
Cdd:PHA03247 2642 PPPTVP---PPERPRDDPAPGRVSRP--RRARRLGRAAQAS------SPPQRPRRRAARPTVGSLTSLADPPPPPPTPEP 2710
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1914 RPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVripFMQKPARRGPPPLARAVPEPGPRgrAGTEAGPGARGGR 1993
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPA---TPGGPARPARPPTTAGPPAPAPP--AAPAAGPPRRLTR 2785
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1994 lglvrvasalssgsessdrsgfrrqltfikespglrrrrselssaesaasaPQGTSPRRGRPALPavflcSSRCEELRAA 2073
Cdd:PHA03247 2786 ---------------------------------------------------PAVASLSESRESLP-----SPWDPADPPA 2809
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2074 PRQAPARQRPPAARPGPGERParrTSSESPSRLPVRAPAARPETVKRYASLPHISVARRPDG----TVPAAPAPADAARR 2149
Cdd:PHA03247 2810 AVLAPAAALPPAASPAGPLPP---PTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSrspaAKPAAPARPPVRRL 2886
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2150 SSDGEPRSLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTPEDAP-AGPPPRKTSDAVVQTE------------ 2216
Cdd:PHA03247 2887 ARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPrPQPPLAPTTDPAGAGEpsgavpqpwlga 2966
|
490 500 510
....*....|....*....|....*....|..
gi 967490223 2217 ----EVAAPKTN-SSTSPSLESREPPGAPASG 2243
Cdd:PHA03247 2967 lvpgRVAVPRFRvPQPAPSREAPASSTPPLTG 2998
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
639-678 |
1.24e-06 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 47.06 E-value: 1.24e-06
10 20 30 40
....*....|....*....|....*....|....*....|
gi 967490223 639 EDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 678
Cdd:pfam00514 2 PENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| ARM |
smart00185 |
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ... |
638-678 |
1.88e-06 |
|
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.
Pssm-ID: 214547 [Multi-domain] Cd Length: 41 Bit Score: 46.27 E-value: 1.88e-06
10 20 30 40
....*....|....*....|....*....|....*....|.
gi 967490223 638 REDYRQVLRDHNCLQTLLQHLTSHSLTIVSNACGTLWNLSA 678
Cdd:smart00185 1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1542-1972 |
2.81e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 52.68 E-value: 2.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1542 PPAAAPTPTHRRTSAIPRALTRERLQGRKEaPAPSKAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPEPPSV 1621
Cdd:PRK07764 401 AAAAAPAAAPAPAAAAPAAAAAPAPAAAPQ-PAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAA 479
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1622 SPRGQEPAVTKDPGPRGGRDSSPS--PRAAEELLQR--CISSALPRRRPPVSGLRrrKPRATRLDERPAEGSREHGEEAA 1697
Cdd:PRK07764 480 PAPAPPAAPAPAAAPAAPAAPAAPagADDAATLRERwpEILAAVPKRSRKTWAIL--LPEATVLGVRGDTLVLGFSTGGL 557
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1698 GSDRASdldsvewraiQEGANSIVTWLHQaaaatreassesdsilsfVSGLSVGSTLQPPKHRKGRQAGGEMGSARRPEK 1777
Cdd:PRK07764 558 ARRFAS----------PGNAEVLVTALAE------------------ELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPP 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1778 RGAASAKTSGSPRSPAGPekPRGTQKTTPGVPAVLRGRTVIY-------VPSPAPRAQPKGTPGPRATPRKVAPPCLAQS 1850
Cdd:PRK07764 610 EEAARPAAPAAPAAPAAP--APAGAAAAPAEASAAPAPGVAApehhpkhVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP 687
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1851 AAPAkvPSPGQQRSRSLHRPGKTSELGTlSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGAS 1930
Cdd:PRK07764 688 AAPA--APAGAAPAQPAPAPAATPPAGQ-ADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAP 764
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 967490223 1931 PVPKTPARTLLAKQHKTQRSPVR--IPFMQKPARRGPPPLARAV 1972
Cdd:PRK07764 765 APAAAPAAAPPPSPPSEEEEMAEddAPSMDDEDRRDAEEVAMEL 808
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1543-1990 |
1.12e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.75 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1543 PAAAPTPTHRRTSAIPRAltrerlqgrkEAPAPSKAAPSAPPPTRAQPSLIADETPPcyslsSSASSLSEPEPPEPPSVS 1622
Cdd:PRK07764 390 GAGAPAAAAPSAAAAAPA----------AAPAPAAAAPAAAAAPAPAAAPQPAPAPA-----PAPAPPSPAGNAPAGGAP 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1623 PRGQEPAVTKDPGPRGGRDSSPSPRAAEEllqrcissalprrrppvsglrrrkPRATRLDERPAEGSREHGEEAAGSDRA 1702
Cdd:PRK07764 455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPA------------------------PPAAPAPAAAPAAPAAPAAPAGADDAA 510
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1703 SDLDSveWRAIQE--GANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQA-GGEMGSARRPEKRG 1779
Cdd:PRK07764 511 TLRER--WPEILAavPKRSRKTWAILLPEATVLGVRGDTLVLGFSTGGLARRFASPGNAEVLVTAlAEELGGDWQVEAVV 588
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1780 AASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVlrgrtviyvPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPSP 1859
Cdd:PRK07764 589 GPAPGAAGGEGPPAPASSGPPEEAARPAAPAA---------PAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV 659
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1860 GQQRSRSLHRPGKTSELGTLSQPPRSATPPARlaktpsssssqtspASQPLPRKRPLVTQAAGPLPGPGASPVPKTPART 1939
Cdd:PRK07764 660 PDASDGGDGWPAKAGGAAPAAPPPAPAPAAPA--------------APAGAAPAQPAPAPAATPPAGQADDPAAQPPQAA 725
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 967490223 1940 llakQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTEAGPGAR 1990
Cdd:PRK07764 726 ----QGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAA 772
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1539-1985 |
1.49e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 50.37 E-value: 1.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1539 DEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPEP 1618
Cdd:PRK07764 391 AGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAP 470
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1619 PSVSPRGQEPAvtkdPGPRGGRDSSPSPRAAEEllqrcisSALPRRRPPVSGLRRRKPRAtrldeRPAEGSREHGEEAAG 1698
Cdd:PRK07764 471 AAAPEPTAAPA----PAPPAAPAPAAAPAAPAA-------PAAPAGADDAATLRERWPEI-----LAAVPKRSRKTWAIL 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1699 SDRAsdldsvewRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKhrkgrQAGGEMGSARRPEKR 1778
Cdd:PRK07764 535 LPEA--------TVLGVRGDTLVLGFSTGGLARRFASPGNAEVLVTALAEELGGDWQVEA-----VVGPAPGAAGGEGPP 601
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1779 GAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAvlRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPS 1858
Cdd:PRK07764 602 APASSGPPEEAARPAAPAAPAAPAAPAPAGAA--AAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPA 679
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1859 PGQQRSRSLHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRkrplVTQAAGPLPG-PGASPVPKTPA 1937
Cdd:PRK07764 680 APPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP----AADDPVPLPPePDDPPDPAGAP 755
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 967490223 1938 RTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTEA 1985
Cdd:PRK07764 756 AQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAEE 803
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1756-2074 |
4.19e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 49.01 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1756 PPKHRKGRQAGGEMGSARRPEKRGAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGrtviyvPSPAPRAQPKGTPGP 1835
Cdd:PHA03307 127 PPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARA------PSSPPAEPPPSTPPA 200
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1836 RATPRKVAPPCLAQSAAPAKVPSPG--------QQRSRSLHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPAS 1907
Cdd:PHA03307 201 AASPRPPRRSSPISASASSPAPAPGrsaaddagASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSS 280
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1908 QPLPRKRPLVTQAAGPLPGPGASPVPKTPARTllakQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTEAGP 1987
Cdd:PHA03307 281 RPGPASSSSSPRERSPSPSPSSPGSGPAPSSP----RASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRP 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1988 GARggrlglvRVASALSSGSESSDRSGFRRQltfikesPGLRRRRSELSSAESAASAPQGTSPRRGRPALPAVFLCSSRC 2067
Cdd:PHA03307 357 PPP-------ADPSSPRKRPRPSRAPSSPAA-------SAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAA 422
|
....*..
gi 967490223 2068 EELRAAP 2074
Cdd:PHA03307 423 SGAFYAR 429
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1815-2293 |
5.55e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.78 E-value: 5.55e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1815 RTVIYVPSPAPRAQPKGTPGPRATPRkvaPPCLAQSAAPAKVPSPGQQRSRSLHRPGKTSELGTL---SQPPRSATPPAR 1891
Cdd:PHA03247 2457 RTILGAPFSLSLLLGELFPGAPVYRR---PAEARFPFAAGAAPDPGGGGPPDPDAPPAPSRLAPAilpDEPVGEPVHPRM 2533
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1892 LAKTPSSSSSQTSPASQPLPRKRPLVTQAAG--PLPGPGASPVPKTPARTLLAK------QHKTQRSPV--RIPFMQKPA 1961
Cdd:PHA03247 2534 LTWIRGLEELASDDAGDPPPPLPPAAPPAAPdrSVPPPRPAPRPSEPAVTSRARrpdappQSARPRAPVddRGDPRGPAP 2613
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1962 RRGPPPLARAVPEPGPrgragteaGPGARGGRLGLVRVASALSSGSESSDRSGFRRQLtfikespglRRRRSELSSAESA 2041
Cdd:PHA03247 2614 PSPLPPDTHAPDPPPP--------SPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSR---------PRRARRLGRAAQA 2676
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2042 ASAPQGTSPRRGRPALPAVflcssrceelraaprqaPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPETVKRY 2121
Cdd:PHA03247 2677 SSPPQRPRRRAARPTVGSL-----------------TSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAP 2739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2122 ASLPhisvarRPDGTVPaapapadaarrssdgePRSLPRVAAPgttwrrirdedvphilrstlPATALPLRgSTPEDAPA 2201
Cdd:PHA03247 2740 APPA------VPAGPAT----------------PGGPARPARP--------------------PTTAGPPA-PAPPAAPA 2776
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2202 GPPPRKTSDAVVQTEEVAAPKTNSSTSPSLESREPPG---------APASGQLSLLGSDVDGPSLAKAPISAPFVHEGlG 2272
Cdd:PHA03247 2777 AGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLApaaalppaaSPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGG-S 2855
|
490 500
....*....|....*....|.
gi 967490223 2273 VAVGGfPASRHGSPSRSARVP 2293
Cdd:PHA03247 2856 VAPGG-DVRRRPPSRSPAAKP 2875
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1746-2136 |
6.78e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 48.44 E-value: 6.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1746 SGLSVGSTLQPPkhrkGRQAGGEMGSARRPEKRGAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAP 1825
Cdd:PRK07764 383 RRLGVAGGAGAP----AAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPP 458
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1826 RAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSrslhRPGKTSELGTLSQPPRSATPPAR--LAKTPSSSSSQT 1903
Cdd:PRK07764 459 AAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAP----AAPAAPAGADDAATLRERWPEILaaVPKRSRKTWAIL 534
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1904 SPASQPLPRKRPLVTQA------AGPLPGPGASPVPKTPARTLLAKQHK------TQRSPVRIPFMQKPARRGPPP-LAR 1970
Cdd:PRK07764 535 LPEATVLGVRGDTLVLGfstgglARRFASPGNAEVLVTALAEELGGDWQveavvgPAPGAAGGEGPPAPASSGPPEeAAR 614
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1971 AVPEPGPRGRAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFrrqlTFIKESPGLRRRRSELSSAESAASAPQGTSP 2050
Cdd:PRK07764 615 PAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAV----PDASDGGDGWPAKAGGAAPAAPPPAPAPAAP 690
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2051 RRGRPALPAvflcssRCEELRAAPRQAPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPETVKRYASLPHISVA 2130
Cdd:PRK07764 691 AAPAGAAPA------QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAP 764
|
....*.
gi 967490223 2131 RRPDGT 2136
Cdd:PRK07764 765 APAAAP 770
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1538-1936 |
1.57e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.09 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1538 SDEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPE 1617
Cdd:PHA03307 62 CDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1618 PPSVSPRGQEPAVTKDPGPRGGRDSSPSPRAAeellqRCISSALPRRRPPVSGLRRRKPRATRLDeRPAEGSREHGEEAA 1697
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAA-----LPLSSPEETARAPSSPPAEPPPSTPPAA-ASPRPPRRSSPISA 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1698 GSDRASDLDsvewraiqegansivtwLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKH----RKGRQAGGEMGSAR 1773
Cdd:PHA03307 216 SASSPAPAP-----------------GRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPapitLPTRIWEASGWNGP 278
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1774 RPEKRGAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGR-TVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAA 1852
Cdd:PHA03307 279 SSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSsRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPP 358
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1853 PAKVPSPgQQRSRSLHRPGKTselgtlSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASPV 1932
Cdd:PHA03307 359 PADPSSP-RKRPRPSRAPSSP------AASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYP 431
|
....
gi 967490223 1933 PKTP 1936
Cdd:PHA03307 432 LLTP 435
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1800-1995 |
4.62e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.64 E-value: 4.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1800 GTQKTTPGVPAVLRGRTVIYVPSPAPRAqPKGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSRSLHRPGKTSELGTL 1879
Cdd:PRK12323 371 GAGPATAAAAPVAQPAPAAAAPAAAAPA-PAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1880 SQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQK 1959
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAESIPDP 529
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 967490223 1960 PARRGPPPLARAVPEPG----PRGRAGTEAGPGARGGRLG 1995
Cdd:PRK12323 530 ATADPDDAFETLAPAPAaapaPRAAAATEPVVAPRPPRAS 569
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1373-1599 |
4.86e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 45.25 E-value: 4.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1373 AAVPARLRKVASALVPGRRALPVPVYMLVPAPARAQEDDsctdsaegtpvnfSSAASLSDETLQGPPRDQPGGPEGRQRP 1452
Cdd:PRK12323 384 QPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-------------PARRSPAPEALAAARQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1453 TGRPTSArqavghrhKAGGAGRSVEQARGTGkNRAGLELPLGRPPSAPADKDDSKPGRTRGDGALQSLCLttpteeavyc 1532
Cdd:PRK12323 451 APAPAAA--------PAAAARPAAAGPRPVA-AAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAP---------- 511
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 967490223 1533 fygNDSDEEPPAAAPTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPSAPPPTRAQPSLIADETPP 1599
Cdd:PRK12323 512 ---AQPDAAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPD 575
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1792-1982 |
4.96e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 45.44 E-value: 4.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1792 PAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSRSLHRPG 1871
Cdd:PHA03378 670 GHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAA 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1872 KTSELGTLSQPPRSATPParlAKTPSSSSSQTSPASQPLPRKRPlvTQAAGPLPGPGASPVPKTPARTLLAKQHKTQRSP 1951
Cdd:PHA03378 750 APGRARPPAAAPGRARPP---AAAPGAPTPQPPPQAPPAPQQRP--RGAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQI 824
|
170 180 190
....*....|....*....|....*....|....*....
gi 967490223 1952 VRIPFMQ-----KPARRGPPPLAR---AVPEPGPRGRAG 1982
Cdd:PHA03378 825 LRQLLTGgvkrgRPSLKKPAALERqaaAGPTPSPGSGTS 863
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1787-2164 |
5.47e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 45.55 E-value: 5.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1787 GSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPSPGQQRSRS 1866
Cdd:PHA03307 25 PATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREG 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1867 LHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASP--------VPKTPAR 1938
Cdd:PHA03307 105 SPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSrqaalplsSPEETAR 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1939 TLLAKQHKTQRSPVRIPFMQKPARRGpPPLARAVPEPGPRG--RAGTEAGPGARGGRLGLVRVASALSSGSESSDRSGFR 2016
Cdd:PHA03307 185 APSSPPAEPPPSTPPAAASPRPPRRS-SPISASASSPAPAPgrSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPI 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2017 RQLTFIKE-SPGLRRRRSELSSAESAASAPQGTSPRRGRPALP-------AVFLCSSRCEELRAAPRQAPARQRPPAARP 2088
Cdd:PHA03307 264 TLPTRIWEaSGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGpapssprASSSSSSSRESSSSSTSSSSESSRGAAVSP 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 967490223 2089 GPGERPARRTSSESPSRLPvrAPAARPETVKRYASLPHISVARRPDGTVPAAPAPADAARRSSDGEPRSLPRVAAP 2164
Cdd:PHA03307 344 GPSPSRSPSPSRPPPPADP--SSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPL 417
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
1647-1860 |
6.70e-04 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 45.24 E-value: 6.70e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1647 RAAEELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGSREHGEEAAGSDRASDLDSVEWRAIQEGANSivtwlHQ 1726
Cdd:PLN03237 1174 KAEEAREKLQRAAARGESGAAKKVSRQAPKKPAPKKTTKKASESETTEETYGSSAMETENVAEVVKPKGRAGA-----KK 1248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1727 AAAATREASSESDSILSFvsglsvgstlqppkhrKGRQAGGEMGSArrPEKRgaaSAKTSGSPRSPAGPEKPRGTQKTTP 1806
Cdd:PLN03237 1249 KAPAAAKEKEEEDEILDL----------------KDRLAAYNLDSA--PAQS---AKMEETVKAVPARRAAARKKPLASV 1307
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 967490223 1807 GVPAVLRGRTVIYVP--SPAPRAQPKGTPGPRATPRKVA-PPCLAQSAAPAKVPSPG 1860
Cdd:PLN03237 1308 SVISDSDDDDDDFAVevSLAERLKKKGGRKPAAANKKAAkPPAAAKKRGPATVQSGQ 1364
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
2072-2321 |
1.08e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.21 E-value: 1.08e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2072 AAPRQAPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPETVKRYASLPHISVARRPDGTVPAAPAPADAARRSS 2151
Cdd:PRK07764 419 AAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA 498
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2152 DGEPRSLPR-VAAPGTTWRRIRdEDVPHILRSTLP-----ATALPLRGST------------------------------ 2195
Cdd:PRK07764 499 APAAPAGADdAATLRERWPEIL-AAVPKRSRKTWAillpeATVLGVRGDTlvlgfstgglarrfaspgnaevlvtalaee 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2196 ------------PEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLESREPPGAPASGqlsllgsdvdGPSLAKAPIS 2263
Cdd:PRK07764 578 lggdwqveavvgPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPA----------EASAAPAPGV 647
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 967490223 2264 APFVHEGLGVAVGGFPASRHGSPSRSARVPPFNYVPSP---MVVAATTDSAAEKAPATSSA 2321
Cdd:PRK07764 648 AAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPapaAPAAPAGAAPAQPAPAPAAT 708
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1628-1991 |
1.11e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.39 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1628 PAVTKDPGPRGGRDSSPSPRA-AEELLQRCISSALPRRRPPVSGLRRRKPRATR-----LDERPAEGSREHGEEAAGSDR 1701
Cdd:PHA03307 55 VVAGAAACDRFEPPTGPPPGPgTEAPANESRSTPTWSLSTLAPASPAREGSPTPpgpssPDPPPPTPPPASPPPSPAPDL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1702 ASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSESDSILSFVSGLSVGSTLQPPKHRKGRQAGGEMGSARRPEKRGAA 1781
Cdd:PHA03307 135 SEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPIS 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1782 SAKTSGSPRSPAGPEKPRG------TQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAK 1855
Cdd:PHA03307 215 ASASSPAPAPGRSAADDAGasssdsSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRER 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1856 VPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKT 1935
Cdd:PHA03307 295 SPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRA 374
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 967490223 1936 PARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTEAGPGARG 1991
Cdd:PHA03307 375 PSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARY 430
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1880-2294 |
1.62e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.62e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1880 SQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPARtllAKQHKTQRSPVRIPFMQK 1959
Cdd:PRK07764 396 AAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAP---SPPPAAAPSAQPAPAPAA 472
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1960 PARRGPPPLARAVPEPGPRGRAGTEAGPGARGGrlglvrvasalssgseSSDRSGFRRQLTFIKES-PGLRRRRSELSSA 2038
Cdd:PRK07764 473 APEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAG----------------ADDAATLRERWPEILAAvPKRSRKTWAILLP 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2039 ESAASAPQGTSPRRG--RPALPAVFLCSSRCEELRAAPRQAPARQRPPAARPGPGERPARRTSSESPSRLPVRAPAARPE 2116
Cdd:PRK07764 537 EATVLGVRGDTLVLGfsTGGLARRFASPGNAEVLVTALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPA 616
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2117 TVKRYASlphisvarrpdgtvPAAPAPADAARRSSDGEPRSLPRVAAPGTTWRRIRDEDVPHILRSTLPATALPLRGSTP 2196
Cdd:PRK07764 617 APAAPAA--------------PAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPP 682
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2197 EDAPAGPPPRKTSDAvvQTEEVAAPKTNSSTSPSLESREPPGAPASGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVG 2276
Cdd:PRK07764 683 PAPAPAAPAAPAGAA--PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPP 760
|
410
....*....|....*...
gi 967490223 2277 GFPASRHGSPSRSARVPP 2294
Cdd:PRK07764 761 PPAPAPAAAPAAAPPPSP 778
|
|
| SAMP |
pfam05924 |
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1645-1666 |
1.62e-03 |
|
SAMP Motif; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). This motif binds axin.
Pssm-ID: 461782 Cd Length: 22 Bit Score: 37.57 E-value: 1.62e-03
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1347-1689 |
1.82e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.62 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1347 EGPAPTGSRPRGAADQELELLRECLGAAVPARLRKVASalVPGRRALPVPVYMLVPAPARAQEDDSCTDSAEGTPVNFSS 1426
Cdd:PHA03307 49 ELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRS--TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASP 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1427 AASLSDETLQGPPRDQPGGPEGRQRPTGRPTSARQAVGHRHKAGGA------GRSVEQARGTGKNRAGLELPLGRPP--- 1497
Cdd:PHA03307 127 PPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAalplssPEETARAPSSPPAEPPPSTPPAAASprp 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1498 -------SAPADKDDSKPGRTRGDGALQSLCLTTPTEEAVyCFYGNDSDEEPPAAAPTPTHRRTSAIPRALTRERLQGRK 1570
Cdd:PHA03307 207 prrsspiSASASSPAPAPGRSAADDAGASSSDSSSSESSG-CGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPA 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1571 EAPAPSKAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPEPPSVSPRGQEPAVTKDPGPRGGRDSSPSPRAAE 1650
Cdd:PHA03307 286 SSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSP 365
|
330 340 350
....*....|....*....|....*....|....*....
gi 967490223 1651 ELLQRCISSALPRRRPPVSGLRRRKPRATRLDERPAEGS 1689
Cdd:PHA03307 366 RKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT 404
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
2047-2301 |
1.95e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.52 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2047 GTSPRRGRPALPAVFLCSSRCEELRAAPRQAPARQRPPAARPGPGERPARRTSsespsrlPVRAPAARPETVKRYASLPh 2126
Cdd:PHA03378 670 GHIPYQPSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATG-------RARPPAAAPGRARPPAAAP- 741
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2127 iSVARRPDGTvpaapapADAARRSSDGEPRSLPRVAAPGTtwrrirdedvphilrstlpatalplrgSTPEDAPAGPPpr 2206
Cdd:PHA03378 742 -GRARPPAAA-------PGRARPPAAAPGRARPPAAAPGA---------------------------PTPQPPPQAPP-- 784
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2207 ktsdavvqteevaAPKTNSSTSPSlESREPPGAPASGQLSLlgsdvDGPSLAKAPISAPFVHEGLGVAVGGFPASRhgSP 2286
Cdd:PHA03378 785 -------------APQQRPRGAPT-PQPPPQAGPTSMQLMP-----RAAPGQQGPTKQILRQLLTGGVKRGRPSLK--KP 843
|
250
....*....|....*
gi 967490223 2287 SRSARVPPFNYVPSP 2301
Cdd:PHA03378 844 AALERQAAAGPTPSP 858
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1756-1993 |
1.98e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.52 E-value: 1.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1756 PPKHRKGRQAGGEMGSARRPEKRGAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQPKGTPGP 1835
Cdd:PHA03378 529 PPQPRAGRRAPCVYTEDLDIESDEPASTEPVHDQLLPAPGLGPLQIQPLTSPTTSQLASSAPSYAQTPWPVPHPSQTPEP 608
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1836 RATpRKVAPpclaQSAAPAKVPSPGQQRS----------------RSLHRPGK---TSELGTLSQPPRSATPPARLAKTP 1896
Cdd:PHA03378 609 PTT-QSHIP----ETSAPRQWPMPLRPIPmrplrmqpitfnvlvfPTPHQPPQveiTPYKPTWTQIGHIPYQPSPTGANT 683
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1897 SSSSSQTSPASQPLPRkrplvtqAAGPLPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPG 1976
Cdd:PHA03378 684 MLPIQWAPGTMQPPPR-------APTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRARPPAAAPGRARP 756
|
250
....*....|....*..
gi 967490223 1977 PRGRAGTEAGPGARGGR 1993
Cdd:PHA03378 757 PAAAPGRARPPAAAPGA 773
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1469-1649 |
2.21e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 43.30 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1469 AGGAGRSVEQARGTGKNRAGLELPLG---RPPSAPADKDDSKPGRTRGDGALQSLCLTTPTEEAVYCFYGNDSDEEPPAA 1545
Cdd:PRK07003 367 APGGGVPARVAGAVPAPGARAAAAVGasaVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGD 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1546 APTPTHRRTSAIPRALTRERLQGRKEAPAPSKAAPS-APPPTRAQPSLIADETPPcyslsssaSSLSEPEPPEPPSVSPR 1624
Cdd:PRK07003 447 APVPAKANARASADSRCDERDAQPPADSGSASAPASdAPPDAAFEPAPRAAAPSA--------ATPAAVPDARAPAAASR 518
|
170 180
....*....|....*....|....*
gi 967490223 1625 GQEPAVTKDPGPRGgrdSSPSPRAA 1649
Cdd:PRK07003 519 EDAPAAAAPPAPEA---RPPTPAAA 540
|
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1410-1432 |
2.33e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.33e-03
|
| APC_r |
pfam05923 |
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis ... |
1284-1305 |
2.45e-03 |
|
APC repeat; This short region is found repeated in the mid region of the adenomatous polyposis proteins (APCs). In the human protein many cancer-linked SNPs are found near the first three occurrences of the motif. These repeats bind beta-catenin.
Pssm-ID: 461781 Cd Length: 24 Bit Score: 37.36 E-value: 2.45e-03
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
2076-2302 |
2.49e-03 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 43.14 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2076 QAPARQRPP--AARPGPGERPARRTSSESPSRLPVRAPAARPETVKRYASLP---HISVARRPDGTVPAAPAPADAARRS 2150
Cdd:PTZ00449 586 KHPKDPEEPkkPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPppqRPSSPERPEGPKIIKSPKPPKSPKP 665
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2151 S----------DGEPRSLPRVAAPGTTwrRIRDEDVPHILRSTLPATAlplrgSTPEDAPAGPPPRKTSDAVVQTEEVAA 2220
Cdd:PTZ00449 666 PfdpkfkekfyDDYLDAAAKSKETKTT--VVLDESFESILKETLPETP-----GTPFTTPRPLPPKLPRDEEFPFEPIGD 738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2221 PkTNSSTSPSlESREPPgAPASGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAvgGFPASRHGSPSRSARVPPFNYVPS 2300
Cdd:PTZ00449 739 P-DAEQPDDI-EFFTPP-EEERTFFHETPADTPLPDILAEEFKEEDIHAETGEP--DEAMKRPDSPSEHEDKPPGDHPSL 813
|
..
gi 967490223 2301 PM 2302
Cdd:PTZ00449 814 PK 815
|
|
| ZapB |
pfam06005 |
Cell division protein ZapB; ZapB is a non-essential, abundant cell division factor that is ... |
22-83 |
3.48e-03 |
|
Cell division protein ZapB; ZapB is a non-essential, abundant cell division factor that is required for proper Z-ring formation.
Pssm-ID: 428718 [Multi-domain] Cd Length: 71 Bit Score: 38.02 E-value: 3.48e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 967490223 22 ELKMASSVAPYEQLVRQVEALKAENSHLRQELRDNSSHLSKLETETSGMKEVLKHLQGKLEQ 83
Cdd:pfam06005 10 ETKIQAAVDTIALLQMENEELKEENEELKEEANELEEENQQLKQERNQWQERIRGLLGKLDE 71
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1207-1705 |
3.91e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 3.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1207 DPCSGQGSGTISPSELPDSP-GQTMPP----------------SRSKTPPLAPAPqgPPEASQFSLQWESYVKRFLDIAd 1269
Cdd:PHA03247 2505 DPDAPPAPSRLAPAILPDEPvGEPVHPrmltwirgleelasddAGDPPPPLPPAA--PPAAPDRSVPPPRPAPRPSEPA- 2581
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1270 CRERCRLPSELDAGSVRFTVEKPDENFSCASSLSALALHEHYVQQDVelrllPSACPERGGGTGGAGLHFAGHRRREEGP 1349
Cdd:PHA03247 2582 VTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPP-----PSPSPAANEPDPHPPPTVPPPERPRDDP 2656
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1350 APT-GSRPRGAADQElellRECLGAAVPARlrkvasalvPGRRALPVPVYMLV-----PAPARAQED-----DSCTDSAE 1418
Cdd:PHA03247 2657 APGrVSRPRRARRLG----RAAQASSPPQR---------PRRRAARPTVGSLTsladpPPPPPTPEPaphalVSATPLPP 2723
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1419 GTPVNFSSAASLSDETLQGPPRDQPGGPEGRQRPTGRPTSA--RQAVGHRHKAGGAGRSVEQARGTGKNRAGLELPLgrp 1496
Cdd:PHA03247 2724 GPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAgpPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPS--- 2800
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1497 PSAPADKDDSKPGRTRGDGALQSLCLTTPTEEAVYcfygNDSDEEPPAAAPTPTHRRTSAIPRALTRERlqGRKEAPAPS 1576
Cdd:PHA03247 2801 PWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQ----PTAPPPPPGPPPPSLPLGGSVAPGGDVRRR--PPSRSPAAK 2874
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1577 KAAPSAPPPTRAQPSLIADETPPCYSLSSSASSLSEPEPPEPPSVSPRGQEPAVTKDPGPRGGRDSSPSPRAAEELLQRC 1656
Cdd:PHA03247 2875 PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGE 2954
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 967490223 1657 ISSALPRR--------RPPVSGLRRRKPRATRLDERPAEGSREHGEEAAGSDRASDL 1705
Cdd:PHA03247 2955 PSGAVPQPwlgalvpgRVAVPRFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1779-2125 |
5.71e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.14 E-value: 5.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1779 GAASAKTSGSPRSPAGpEKPRGTQKTTPGVPAVLRgrtviyvpspAPRAQPKGTPGPRATPRKVAPPCLAQSAAPAKVPS 1858
Cdd:PRK07003 363 TGGGAPGGGVPARVAG-AVPAPGARAAAAVGASAV----------PAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPA 431
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1859 PGQQrsrslhrpgktselGTLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPLVTQAAGPLPGPGASPVPKTPAr 1938
Cdd:PRK07003 432 PPAT--------------ADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAFEPAPRA- 496
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1939 tllAKQHKTQRSPVRIPFMQKPARRGPPPLARAVPEPGPRGRAGTEAGPGARGGrlglvrvasalssgsessdrsGFRRQ 2018
Cdd:PRK07003 497 ---AAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARPPTPAAAAPAARAG---------------------GAAAA 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 2019 LTFIKeSPGLRrrrselssaesaasapqgTSPRRGRPALPAvflcssrceelrAAPRQAPARQRPPAARPGPGERPARRT 2098
Cdd:PRK07003 553 LDVLR-NAGMR------------------VSSDRGARAAAA------------AKPAAAPAAAPKPAAPRVAVQVPTPRA 601
|
330 340
....*....|....*....|....*..
gi 967490223 2099 SSESPSRLPVRAPAARPETVKRYASLP 2125
Cdd:PRK07003 602 RAATGDAPPNGAARAEQAAESRGAPPP 628
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
1755-1977 |
7.71e-03 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 41.59 E-value: 7.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1755 QPPKHRKGRQ--AGGEMGSARRPEK---RGAASAKTSGSPRSPAGPEKPRGTQKTTPGVPAVLRGRTVIYVPSPAPRAQP 1829
Cdd:PHA03378 715 QRPAAATGRArpPAAAPGRARPPAAapgRARPPAAAPGRARPPAAAPGRARPPAAAPGAPTPQPPPQAPPAPQQRPRGAP 794
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 967490223 1830 KGTPGPRA--TPRKVAPPclaqsaAPAKVPSPGQQRSRSLHRPGKTSELGTLSQPPRSATPPARLAKTPSSSSSQTSPAS 1907
Cdd:PHA03378 795 TPQPPPQAgpTSMQLMPR------AAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQAAAGPTPSPGSGTSDKIVQ 868
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 967490223 1908 QPL---PRKRPLVTQAAGPLPGP-GASPVPKTPARTLLAKQHKTQRSPVRIPfmqkPARRGPpplARAVPEPGP 1977
Cdd:PHA03378 869 APVfypPVLQPIQVMRQLGSVRAaAASTVTQAPTEYTGERRGVGPMHPTDIP----PSKRAK---TDAYVESQP 935
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
549-586 |
9.47e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.47e-03
10 20 30
....*....|....*....|....*....|....*...
gi 967490223 549 KKVLREAGSVTALVQCvLRATKESTLKSVLSALWNLSA 586
Cdd:pfam00514 5 KQAVIEAGAVPPLVRL-LSSPDEEVQEEAAWALSNLAA 41
|
|
| Arm |
pfam00514 |
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ... |
685-720 |
9.95e-03 |
|
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.
Pssm-ID: 425727 [Multi-domain] Cd Length: 41 Bit Score: 35.89 E-value: 9.95e-03
10 20 30
....*....|....*....|....*....|....*.
gi 967490223 685 ELLWDLGAVGMLRNLVHSKHKMIAMGSAAALRNLLA 720
Cdd:pfam00514 6 QAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLAA 41
|
|
| |
