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Conserved domains on  [gi|1046869346|ref|XP_008770443|]
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zinc finger protein 407 isoform X1 [Rattus norvegicus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 10604184)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677|GO:0003700
PubMed:  11179890|12665246|11361095|10940247|22803940|30718982
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1717-1742 2.25e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.25e-04
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1717 HLTRHKRVHTGEKPYRCPWCDYRSNC 1742
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1703-1727 7.56e-04

C2H2-type zinc-finger domain;


:

Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.56e-04
                           10        20
                   ....*....|....*....|....*
gi 1046869346 1703 FKCDECNFASTTQSHLTRHKRVHTG 1727
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1546-1567 1.09e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.09e-03
                           10        20
                   ....*....|....*....|..
gi 1046869346 1546 HIRTHTGSKPFKCKICHFATAQ 1567
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1689-1714 1.92e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.92e-03
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1689 ALTKHRRQHTGEKPFKCDECNFASTT 1714
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1631-1658 2.11e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 2.11e-03
                           10        20
                   ....*....|....*....|....*...
gi 1046869346 1631 ALNNHVKLHTGEKPFKCtwPTCHYSFLT 1658
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1717-1742 2.25e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.25e-04
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1717 HLTRHKRVHTGEKPYRCPWCDYRSNC 1742
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1703-1727 7.56e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.56e-04
                           10        20
                   ....*....|....*....|....*
gi 1046869346 1703 FKCDECNFASTTQSHLTRHKRVHTG 1727
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1546-1567 1.09e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.09e-03
                           10        20
                   ....*....|....*....|..
gi 1046869346 1546 HIRTHTGSKPFKCKICHFATAQ 1567
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1689-1714 1.92e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.92e-03
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1689 ALTKHRRQHTGEKPFKCDECNFASTT 1714
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1631-1658 2.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 2.11e-03
                           10        20
                   ....*....|....*....|....*...
gi 1046869346 1631 ALNNHVKLHTGEKPFKCtwPTCHYSFLT 1658
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1701-1756 4.25e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.99  E-value: 4.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1046869346 1701 KPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWC---DYRSNCAENIRKHILHTGKH 1756
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSgcdKSFSRPLELSRHLRTHHNNP 90
 
Name Accession Description Interval E-value
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1717-1742 2.25e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.05  E-value: 2.25e-04
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1717 HLTRHKRVHTGEKPYRCPWCDYRSNC 1742
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_5 pfam13909
C2H2-type zinc-finger domain;
1703-1727 7.56e-04

C2H2-type zinc-finger domain;


Pssm-ID: 404746 [Multi-domain]  Cd Length: 25  Bit Score: 38.69  E-value: 7.56e-04
                           10        20
                   ....*....|....*....|....*
gi 1046869346 1703 FKCDECNFASTTQSHLTRHKRVHTG 1727
Cdd:pfam13909    1 YKCSQCDYSTAWKSNLKRHLRKHTG 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1546-1567 1.09e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.12  E-value: 1.09e-03
                           10        20
                   ....*....|....*....|..
gi 1046869346 1546 HIRTHTGSKPFKCKICHFATAQ 1567
Cdd:pfam13465    5 HMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1689-1714 1.92e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 1.92e-03
                           10        20
                   ....*....|....*....|....*.
gi 1046869346 1689 ALTKHRRQHTGEKPFKCDECNFASTT 1714
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1631-1658 2.11e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.35  E-value: 2.11e-03
                           10        20
                   ....*....|....*....|....*...
gi 1046869346 1631 ALNNHVKLHTGEKPFKCtwPTCHYSFLT 1658
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKC--PECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1701-1756 4.25e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 41.99  E-value: 4.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1046869346 1701 KPFKCDECNFASTTQSHLTRHKRVHTGEKPYRCPWC---DYRSNCAENIRKHILHTGKH 1756
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSgcdKSFSRPLELSRHLRTHHNNP 90
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 1684-1753 5.83e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 41.63  E-value: 5.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1046869346 1684 GGTRHALTKHRRQHT-GEKPFKCD--ECNFASTTQSHLTRHKR-------------------VHTGEKPYRCPWCDYRSN 1741
Cdd:COG5189    330 GGERNIDTPSRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpspekmniFSAKDKPYRCEVCDKRYK 409

                           90
                   ....*....|..
gi 1046869346 1742 CAENIRKHILHT 1753
Cdd:COG5189    410 NLNGLKYHRKHS 421
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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