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Conserved domains on  [gi|1370487809|ref|XP_006713995|]
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protein FAM193A isoform X2 [Homo sapiens]

Protein Classification

PTZ00449 and FAM193_C domain-containing protein( domain architecture ID 11239807)

PTZ00449 and FAM193_C domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FAM193_C pfam15914
FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 ...
 1483-1538 2.40e-29

FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. This C-terminal region of these proteins carries the most conserved residues.


:

Pssm-ID: 464940  Cd Length: 57  Bit Score: 111.55  E-value: 2.40e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370487809 1483 DVFLPKDIDLDSVDMDETEREVEYFKRFCLDSARQTR-QRLSINWSNFSLKKATFAA 1538
Cdd:pfam15914    1 DVFLPKDIDLDDVEMDDTEREVEYFKRFCLDSAPQTRkQKVHVNWKDFSLKKKTTAA 57
PRK12323 super family cl46901
DNA polymerase III subunit gamma/tau;
976-1053 3.42e-03

DNA polymerase III subunit gamma/tau;


The actual alignment was detected with superfamily member PRK12323:

Pssm-ID: 481241 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 3.42e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370487809  976 AAPRnsPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSV 1053
Cdd:PRK12323   372 AGPA--TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447
 
Name Accession Description Interval E-value
FAM193_C pfam15914
FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 ...
 1483-1538 2.40e-29

FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. This C-terminal region of these proteins carries the most conserved residues.


Pssm-ID: 464940  Cd Length: 57  Bit Score: 111.55  E-value: 2.40e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370487809 1483 DVFLPKDIDLDSVDMDETEREVEYFKRFCLDSARQTR-QRLSINWSNFSLKKATFAA 1538
Cdd:pfam15914    1 DVFLPKDIDLDDVEMDDTEREVEYFKRFCLDSAPQTRkQKVHVNWKDFSLKKKTTAA 57
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
976-1053 3.42e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 3.42e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370487809  976 AAPRnsPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSV 1053
Cdd:PRK12323   372 AGPA--TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447
 
Name Accession Description Interval E-value
FAM193_C pfam15914
FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 ...
 1483-1538 2.40e-29

FAM193 family C-terminal; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. This C-terminal region of these proteins carries the most conserved residues.


Pssm-ID: 464940  Cd Length: 57  Bit Score: 111.55  E-value: 2.40e-29
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370487809 1483 DVFLPKDIDLDSVDMDETEREVEYFKRFCLDSARQTR-QRLSINWSNFSLKKATFAA 1538
Cdd:pfam15914    1 DVFLPKDIDLDDVEMDDTEREVEYFKRFCLDSAPQTRkQKVHVNWKDFSLKKKTTAA 57
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
976-1053 3.42e-03

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 42.17  E-value: 3.42e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370487809  976 AAPRnsPTGLAPLPALSPAALSPAALSPASTPHLANLAAPSFPKTATTTPGFVDTRKSFCPAPLPPATDGSISAPPSV 1053
Cdd:PRK12323   372 AGPA--TAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGA 447
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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