secreted phosphoprotein 24 isoform X1 [Mus musculus]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| Cathelicidins super family | cl29764 | Cathelicidin; A novel protein family, showing a conserved proregion and a variable ... |
67-108 | 6.58e-21 | ||
Cathelicidin; A novel protein family, showing a conserved proregion and a variable carboxyl-terminal antimicrobial domain. This region shows similarity to cystatins. The actual alignment was detected with superfamily member pfam07448: Pssm-ID: 453055 Cd Length: 64 Bit Score: 79.09 E-value: 6.58e-21
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| CY super family | cl09238 | Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ... |
32-100 | 2.62e-03 | ||
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains. The actual alignment was detected with superfamily member pfam00031: Pssm-ID: 447698 Cd Length: 92 Bit Score: 34.62 E-value: 2.62e-03
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| Name | Accession | Description | Interval | E-value | ||
| Spp-24 | pfam07448 | Secreted phosphoprotein 24 (Spp-24) cystatin-like domain; This family represents a conserved ... |
67-108 | 6.58e-21 | ||
Secreted phosphoprotein 24 (Spp-24) cystatin-like domain; This family represents a conserved region approximately 60 residues long within secreted phosphoprotein 24 (Spp-24), which seems to be restricted to vertebrates. This is a non-collagenous protein found in bone that is related in sequence to the cystatin family of thiol protease inhibitors. This suggests that Spp-24 could function to modulate the thiol protease activities known to be involved in bone turnover. It is also possible that the intact form of Spp-24 found in bone could be a precursor to a biologically active peptide that coordinates an aspect of bone turnover. Pssm-ID: 429466 Cd Length: 64 Bit Score: 79.09 E-value: 6.58e-21
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| Cystatin | pfam00031 | Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ... |
32-100 | 2.62e-03 | ||
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included. Pssm-ID: 425431 Cd Length: 92 Bit Score: 34.62 E-value: 2.62e-03
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| CY | smart00043 | Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ... |
34-98 | 4.63e-03 | ||
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains. Pssm-ID: 214484 Cd Length: 107 Bit Score: 33.94 E-value: 4.63e-03
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| Name | Accession | Description | Interval | E-value | ||
| Spp-24 | pfam07448 | Secreted phosphoprotein 24 (Spp-24) cystatin-like domain; This family represents a conserved ... |
67-108 | 6.58e-21 | ||
Secreted phosphoprotein 24 (Spp-24) cystatin-like domain; This family represents a conserved region approximately 60 residues long within secreted phosphoprotein 24 (Spp-24), which seems to be restricted to vertebrates. This is a non-collagenous protein found in bone that is related in sequence to the cystatin family of thiol protease inhibitors. This suggests that Spp-24 could function to modulate the thiol protease activities known to be involved in bone turnover. It is also possible that the intact form of Spp-24 found in bone could be a precursor to a biologically active peptide that coordinates an aspect of bone turnover. Pssm-ID: 429466 Cd Length: 64 Bit Score: 79.09 E-value: 6.58e-21
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| Cystatin | pfam00031 | Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ... |
32-100 | 2.62e-03 | ||
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included. Pssm-ID: 425431 Cd Length: 92 Bit Score: 34.62 E-value: 2.62e-03
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| CY | smart00043 | Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ... |
34-98 | 4.63e-03 | ||
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains. Pssm-ID: 214484 Cd Length: 107 Bit Score: 33.94 E-value: 4.63e-03
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| Blast search parameters | ||||
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