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Conserved domains on  [gi|564365568|ref|XP_006243882|]
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microtubule-associated protein 4 isoform X14 [Rattus norvegicus]

Protein Classification

PHA03247 and Tubulin-binding domain-containing protein( domain architecture ID 10450448)

PHA03247 and Tubulin-binding domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1968-1997 2.84e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 2.84e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1968 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 1997
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1999-2028 4.53e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.53e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1999 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2028
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2030-2060 9.16e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 9.16e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 564365568  2030 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2060
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1907-1928 5.31e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 47.41  E-value: 5.31e-07
                           10        20
                   ....*....|....*....|..
gi 564365568  1907 DLKSVRSKVGSTENMKHQPGGG 1928
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 super family cl33720
large tegument protein UL36; Provisional
 1687-1964 1.35e-04

large tegument protein UL36; Provisional


The actual alignment was detected with superfamily member PHA03247:

Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1687 PTKSRGPTPHQPKSASQERerakllKASGVSRQEEGKAAVGLTGNDIATPPNKELPPSPEKKAKPITETKVAEKRTSPSK 1766
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRAR------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHP 2642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1767 PSSAPAlRPGPKTTPTISKATSPS-TLVSTGSSSRSPSTTLPKRPTTTKTEG------KPADVKRMTAKSATADLSRSKT 1839
Cdd:PHA03247 2643 PPTVPP-PERPRDDPAPGRVSRPRrARRLGRAAQASSPPQRPRRRAARPTVGsltslaDPPPPPPTPEPAPHALVSATPL 2721

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1840 TSASSVKRNTTPT-----GATPPAGMASTRVKPMSAPCRSSVALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSK 1914
Cdd:PHA03247 2722 PPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 564365568 1915 VGSTENMKHQPGGGRAkveKKTEAATTAGNPEPNAVTKAASSISSAPKPP 1964
Cdd:PHA03247 2802 WDPADPPAAVLAPAAA---LPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1968-1997 2.84e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 2.84e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1968 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 1997
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1999-2028 4.53e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.53e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1999 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2028
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2030-2060 9.16e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 9.16e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 564365568  2030 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2060
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1907-1928 5.31e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 47.41  E-value: 5.31e-07
                           10        20
                   ....*....|....*....|..
gi 564365568  1907 DLKSVRSKVGSTENMKHQPGGG 1928
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1687-1964 1.35e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1687 PTKSRGPTPHQPKSASQERerakllKASGVSRQEEGKAAVGLTGNDIATPPNKELPPSPEKKAKPITETKVAEKRTSPSK 1766
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRAR------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHP 2642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1767 PSSAPAlRPGPKTTPTISKATSPS-TLVSTGSSSRSPSTTLPKRPTTTKTEG------KPADVKRMTAKSATADLSRSKT 1839
Cdd:PHA03247 2643 PPTVPP-PERPRDDPAPGRVSRPRrARRLGRAAQASSPPQRPRRRAARPTVGsltslaDPPPPPPTPEPAPHALVSATPL 2721

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1840 TSASSVKRNTTPT-----GATPPAGMASTRVKPMSAPCRSSVALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSK 1914
Cdd:PHA03247 2722 PPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 564365568 1915 VGSTENMKHQPGGGRAkveKKTEAATTAGNPEPNAVTKAASSISSAPKPP 1964
Cdd:PHA03247 2802 WDPADPPAAVLAPAAA---LPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1733-1963 1.03e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1733 IATPPNKELPPSPEKKAKPITETKVAEKRTSPSKPSSAPALRPGPKTTPTISKATSPSTLVSTGSSSRSPSTTLPKRPTT 1812
Cdd:pfam05109  548 VTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATS 627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1813 TKTEGK----PADVKRMTAKSATADLSRSKTTSASSVKRNTTPTGATPPAGMASTRVKPMSA-------------PCRSS 1875
Cdd:pfam05109  628 AVTTGQhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTsthhvstsspaprPGTTS 707

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1876 VALSVDKKPTSTKP------------SSSAPRVSRLATTvSAPDLKSVRSKVGSTENMKHQPG-GGRAKVEKKTEAATTA 1942
Cdd:pfam05109  708 QASGPGNSSTSTKPgevnvtkgtppkNATSPQAPSGQKT-AVPTVTSTGGKANSTTGGKHTTGhGARTSTEPTTDYGGDS 786

                          250       260
                   ....*....|....*....|...
gi 564365568  1943 GNPEP--NAVTKAASSISSAPKP 1963
Cdd:pfam05109  787 TTPRTryNATTYLPPSTSSKLRP 809
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1968-1997 2.84e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.51  E-value: 2.84e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1968 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 1997
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1999-2028 4.53e-13

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 64.74  E-value: 4.53e-13
                           10        20        30
                   ....*....|....*....|....*....|
gi 564365568  1999 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 2028
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 2030-2060 9.16e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 52.41  E-value: 9.16e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 564365568  2030 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 2060
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 1907-1928 5.31e-07

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 47.41  E-value: 5.31e-07
                           10        20
                   ....*....|....*....|..
gi 564365568  1907 DLKSVRSKVGSTENMKHQPGGG 1928
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1687-1964 1.35e-04

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 47.63  E-value: 1.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1687 PTKSRGPTPHQPKSASQERerakllKASGVSRQEEGKAAVGLTGNDIATPPNKELPPSPEKKAKPITETKVAEKRTSPSK 1766
Cdd:PHA03247 2569 PPPRPAPRPSEPAVTSRAR------RPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHP 2642

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1767 PSSAPAlRPGPKTTPTISKATSPS-TLVSTGSSSRSPSTTLPKRPTTTKTEG------KPADVKRMTAKSATADLSRSKT 1839
Cdd:PHA03247 2643 PPTVPP-PERPRDDPAPGRVSRPRrARRLGRAAQASSPPQRPRRRAARPTVGsltslaDPPPPPPTPEPAPHALVSATPL 2721

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1840 TSASSVKRNTTPT-----GATPPAGMASTRVKPMSAPCRSSVALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSK 1914
Cdd:PHA03247 2722 PPGPAAARQASPAlpaapAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSP 2801

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|
gi 564365568 1915 VGSTENMKHQPGGGRAkveKKTEAATTAGNPEPNAVTKAASSISSAPKPP 1964
Cdd:PHA03247 2802 WDPADPPAAVLAPAAA---LPPAASPAGPLPPPTSAQPTAPPPPPGPPPP 2848
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1733-1963 1.03e-03

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 44.14  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1733 IATPPNKELPPSPEKKAKPITETKVAEKRTSPSKPSSAPALRPGPKTTPTISKATSPSTLVSTGSSSRSPSTTLPKRPTT 1812
Cdd:pfam05109  548 VTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATS 627

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1813 TKTEGK----PADVKRMTAKSATADLSRSKTTSASSVKRNTTPTGATPPAGMASTRVKPMSA-------------PCRSS 1875
Cdd:pfam05109  628 AVTTGQhnitSSSTSSMSLRPSSISETLSPSTSDNSTSHMPLLTSAHPTGGENITQVTPASTsthhvstsspaprPGTTS 707

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568  1876 VALSVDKKPTSTKP------------SSSAPRVSRLATTvSAPDLKSVRSKVGSTENMKHQPG-GGRAKVEKKTEAATTA 1942
Cdd:pfam05109  708 QASGPGNSSTSTKPgevnvtkgtppkNATSPQAPSGQKT-AVPTVTSTGGKANSTTGGKHTTGhGARTSTEPTTDYGGDS 786

                          250       260
                   ....*....|....*....|...
gi 564365568  1943 GNPEP--NAVTKAASSISSAPKP 1963
Cdd:pfam05109  787 TTPRTryNATTYLPPSTSSKLRP 809
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 1657-1964 4.60e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 42.37  E-value: 4.60e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1657 QKITGKSELKVLD-ERKKEDKSKMAVKGymrPTKSRGP--TPHQPKSASQERERAKLLKASgvsrQEEGKAAVGLTGNDI 1733
Cdd:PTZ00449  486 KKLIKKSKKKLAPiEEEDSDKHDEPPEG---PEASGLPpkAPGDKEGEEGEHEDSKESDEP----KEGGKPGETKEGEVG 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1734 ATP-PNKELPPS--------PE--KKAKPITETKVAEKRTSPSKPSSaPALRPGPKtTPTISK----------ATSPSTL 1792
Cdd:PTZ00449  559 KKPgPAKEHKPSkiptlskkPEfpKDPKHPKDPEEPKKPKRPRSAQR-PTRPKSPK-LPELLDipkspkrpesPKSPKRP 636

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1793 VSTGSSSRSPSTTLPKRPTTTKTEGKPA-----DVKRMTAKSATADLSRSKTT--------SASSVKRNTTPtgATPPAG 1859
Cdd:PTZ00449  637 PPPQRPSSPERPEGPKIIKSPKPPKSPKppfdpKFKEKFYDDYLDAAAKSKETkttvvldeSFESILKETLP--ETPGTP 714

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1860 MASTRVKPMSAPCRSSVALSVDKKPTSTKPSSSaprvsrlaTTVSAPDLKSVRSKvgstENMKHQPGGGRAKVEKKTEAA 1939
Cdd:PTZ00449  715 FTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDI--------EFFTPPEEERTFFH----ETPADTPLPDILAEEFKEEDI 782

                         330       340
                  ....*....|....*....|....*
gi 564365568 1940 TTAGNPEPNAVTKAASSISSAPKPP 1964
Cdd:PTZ00449  783 HAETGEPDEAMKRPDSPSEHEDKPP 807
PHA03247 PHA03247
large tegument protein UL36; Provisional
 1686-1894 9.56e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.46  E-value: 9.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1686 RPTKSRGPTPHQPKSAsqeRERAKLLKASGVSRQEEGKAAVGLTGNDIATPPNKELPPSPEKKAKPIT------------ 1753
Cdd:PHA03247 2713 HALVSATPLPPGPAAA---RQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAgpprrltrpava 2789

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564365568 1754 -ETKVAEKRTSPSKPSSAPALRPGPktTPTISKATSPSTLVSTGSSSRSPSTTLPKRP--TTTKTEGKPAdvkrmtaksA 1830
Cdd:PHA03247 2790 sLSESRESLPSPWDPADPPAAVLAP--AAALPPAASPAGPLPPPTSAQPTAPPPPPGPppPSLPLGGSVA---------P 2858

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564365568 1831 TADLSRskttsassvkRNTTPTGATPPAGMASTRVKPMSAPCRS----SVALSVDKKPTSTKPSSSAP 1894
Cdd:PHA03247 2859 GGDVRR----------RPPSRSPAAKPAAPARPPVRRLARPAVSrsteSFALPPDQPERPPQPQAPPP 2916
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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