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Conserved domains on  [gi|564335578|ref|XP_006232116|]
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zinc finger RNA-binding protein isoform X3 [Rattus norvegicus]

Protein Classification

zinc finger RNA-binding protein( domain architecture ID 13915102)

zinc finger RNA-binding protein is involved in postimplantation and gastrulation stages of development

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003676
PubMed:  11361095|22803940|30718982|10940247|12665246|11179890
SCOP:  4003583

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DZF smart00572
domain in DSRM or ZnF_C2H2 domain containing proteins;
747-1001 5.98e-140

domain in DSRM or ZnF_C2H2 domain containing proteins;


:

Pssm-ID: 128842  Cd Length: 246  Bit Score: 419.47  E-value: 5.98e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    747 ALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVISPekydikcavSEAAIILNSCVEPKMQV 826
Cdd:smart00572    1 TLKGVMRVGSFAKGTLLKGDNVAELVLLCKEKPTSELVARLARKLPEQLKAVTE---------DEALIIVTSTKEPTMEV 71

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    827 TITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFP 906
Cdd:smart00572   72 GILITSPLARVELLITTVPENLRKLDPEDHLDRKKCLSALASLRHAKWFQARASGLQSCVIVIRVLRDLCNRVPTWQPLS 151

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    907 SWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAF 986
Cdd:smart00572  152 GWPLELLVEKAIGSARQPLGLGDAFRRVFECLASGILLPGSPGLTDPCEKDNTDALTALTLQQREDVTASAQTALRLLAF 231

                           250
                    ....*....|....*
gi 564335578    987 RQIHKVLGMDPLPQM 1001
Cdd:smart00572  232 GQIHKILGMDPLPSM 246
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 544-575 8.27e-08

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 49.17  E-value: 8.27e-08
                            10        20        30
                    ....*....|....*....|....*....|..
gi 564335578    544 RFHCKLCECSFNDPNAKEMHLKGRRHRLQYKK 575
Cdd:smart00451    3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 294-323 6.35e-07

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 46.48  E-value: 6.35e-07
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    294 HYCDVCKISCAGPQTYKEHLEGQKHKKKEA 323
Cdd:smart00451    4 FYCKLCNVTFTDEISVEAHLKGKKHKKNVK 33
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 347-376 7.08e-06

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


:

Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 43.78  E-value: 7.08e-06
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    347 CELCDVSCTGADAYAAHIRGAKHQKVVKLH 376
Cdd:smart00451    6 CKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PHA03255 super family cl31530
BDLF3; Provisional
 345-514 1.23e-05

BDLF3; Provisional


The actual alignment was detected with superfamily member PHA03255:

Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 47.98  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  345 LRCE--LCDVSCTGADAYAAHIRGAkhqkvvklhTKLGKPIPSTEPNVVSQATSSTAVSASKPTaspSSIGASNCTLNTS 422
Cdd:PHA03255   16 LICEtsLIWTSSGSSTASAGNVTGT---------TAVTTPSPSASGPSTNQSTTLTTTSAPITT---TAILSTNTTTVTS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  423 SiaTTSVKGLSTTGN-SSLNSTSNTKVSAVPTNMAAKKTSTPKINfvgGNKLQSTGNKAEDLKGTDCIKNNPAASAVQIP 501
Cdd:PHA03255   84 T--GTTVTPVPTTSNaSTINVTTKVTAQNITATEAGTGTSTGVTS---NVTTRSSSTTSATTRITNATTLAPTLSSKGTS 158

                         170
                  ....*....|...
gi 564335578  502 EVKQDAVSEPVTP 514
Cdd:PHA03255  159 NATKTTAELPTVP 171
 
Name Accession Description Interval E-value
DZF smart00572
domain in DSRM or ZnF_C2H2 domain containing proteins;
747-1001 5.98e-140

domain in DSRM or ZnF_C2H2 domain containing proteins;


Pssm-ID: 128842  Cd Length: 246  Bit Score: 419.47  E-value: 5.98e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    747 ALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVISPekydikcavSEAAIILNSCVEPKMQV 826
Cdd:smart00572    1 TLKGVMRVGSFAKGTLLKGDNVAELVLLCKEKPTSELVARLARKLPEQLKAVTE---------DEALIIVTSTKEPTMEV 71

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    827 TITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFP 906
Cdd:smart00572   72 GILITSPLARVELLITTVPENLRKLDPEDHLDRKKCLSALASLRHAKWFQARASGLQSCVIVIRVLRDLCNRVPTWQPLS 151

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    907 SWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAF 986
Cdd:smart00572  152 GWPLELLVEKAIGSARQPLGLGDAFRRVFECLASGILLPGSPGLTDPCEKDNTDALTALTLQQREDVTASAQTALRLLAF 231

                           250
                    ....*....|....*
gi 564335578    987 RQIHKVLGMDPLPQM 1001
Cdd:smart00572  232 GQIHKILGMDPLPSM 246
DZF pfam07528
DZF domain; The function of this domain is unknown. It is often found associated with ...
 753-999 1.36e-74

DZF domain; The function of this domain is unknown. It is often found associated with pfam00098 or pfam00035. This domain has been predicted to belong to the nucleotidyltransferase superfamily.


Pssm-ID: 284860  Cd Length: 248  Bit Score: 246.33  E-value: 1.36e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   753 RVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVISPekyDIKCAVSEAAIILNSCVEPKMQVTITLTS 832
Cdd:pfam07528    1 QVGSFKKGTLLKGSNVADVVVILKTLPTTELVDALAKKVEEDLKTSMK---TEILQSVEALIVIKNTKEPPLELGFHITS 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   833 PIIRE--------ENMRegdvtsgmVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSD 904
Cdd:pfam07528   78 PVAKVrmliatlpENLR--------KLEPEDHLDRKKMQSHLASIRHTRWFEENAHHLKSIKVLIRVLKDLCRRFDTFGP 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   905 FPSWAMELLVEKAISSASSPQS--PGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALR 982
Cdd:pfam07528  150 LSGWPLDLLAHKAIMNNPSRQAlpAGEAFRRVFELLASGIFLPGSAGITDPCEKGHTRVHTHLTLQQQDDCCMTAQTLLR 229

                          250
                   ....*....|....*..
gi 564335578   983 LLAFRQIHKVLGMDPLP 999
Cdd:pfam07528  230 VLAHGGYKHILGMDGNT 246
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 544-575 8.27e-08

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 49.17  E-value: 8.27e-08
                            10        20        30
                    ....*....|....*....|....*....|..
gi 564335578    544 RFHCKLCECSFNDPNAKEMHLKGRRHRLQYKK 575
Cdd:smart00451    3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 294-323 6.35e-07

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 46.48  E-value: 6.35e-07
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    294 HYCDVCKISCAGPQTYKEHLEGQKHKKKEA 323
Cdd:smart00451    4 FYCKLCNVTFTDEISVEAHLKGKKHKKNVK 33
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 347-376 7.08e-06

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 43.78  E-value: 7.08e-06
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    347 CELCDVSCTGADAYAAHIRGAKHQKVVKLH 376
Cdd:smart00451    6 CKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PHA03255 PHA03255
BDLF3; Provisional
 345-514 1.23e-05

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 47.98  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  345 LRCE--LCDVSCTGADAYAAHIRGAkhqkvvklhTKLGKPIPSTEPNVVSQATSSTAVSASKPTaspSSIGASNCTLNTS 422
Cdd:PHA03255   16 LICEtsLIWTSSGSSTASAGNVTGT---------TAVTTPSPSASGPSTNQSTTLTTTSAPITT---TAILSTNTTTVTS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  423 SiaTTSVKGLSTTGN-SSLNSTSNTKVSAVPTNMAAKKTSTPKINfvgGNKLQSTGNKAEDLKGTDCIKNNPAASAVQIP 501
Cdd:PHA03255   84 T--GTTVTPVPTTSNaSTINVTTKVTAQNITATEAGTGTSTGVTS---NVTTRSSSTTSATTRITNATTLAPTLSSKGTS 158

                         170
                  ....*....|...
gi 564335578  502 EVKQDAVSEPVTP 514
Cdd:PHA03255  159 NATKTTAELPTVP 171
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 545-569 6.47e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.56  E-value: 6.47e-05
                           10        20
                   ....*....|....*....|....*
gi 564335578   545 FHCKLCECSFNDPNAKEMHLKGRRH 569
Cdd:pfam12874    1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 295-318 7.42e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.56  E-value: 7.42e-05
                           10        20
                   ....*....|....*....|....
gi 564335578   295 YCDVCKISCAGPQTYKEHLEGQKH 318
Cdd:pfam12874    2 YCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 345-369 2.36e-04

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 39.02  E-value: 2.36e-04
                           10        20
                   ....*....|....*....|....*
gi 564335578   345 LRCELCDVSCTGADAYAAHIRGAKH 369
Cdd:pfam12874    1 FYCELCNVTFNSESQLKSHLQGKKH 25
 
Name Accession Description Interval E-value
DZF smart00572
domain in DSRM or ZnF_C2H2 domain containing proteins;
747-1001 5.98e-140

domain in DSRM or ZnF_C2H2 domain containing proteins;


Pssm-ID: 128842  Cd Length: 246  Bit Score: 419.47  E-value: 5.98e-140
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    747 ALKGVLRVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVISPekydikcavSEAAIILNSCVEPKMQV 826
Cdd:smart00572    1 TLKGVMRVGSFAKGTLLKGDNVAELVLLCKEKPTSELVARLARKLPEQLKAVTE---------DEALIIVTSTKEPTMEV 71

                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    827 TITLTSPIIREENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSDFP 906
Cdd:smart00572   72 GILITSPLARVELLITTVPENLRKLDPEDHLDRKKCLSALASLRHAKWFQARASGLQSCVIVIRVLRDLCNRVPTWQPLS 151

                           170       180       190       200       210       220       230       240
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578    907 SWAMELLVEKAISSASSPQSPGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALRLLAF 986
Cdd:smart00572  152 GWPLELLVEKAIGSARQPLGLGDAFRRVFECLASGILLPGSPGLTDPCEKDNTDALTALTLQQREDVTASAQTALRLLAF 231

                           250
                    ....*....|....*
gi 564335578    987 RQIHKVLGMDPLPQM 1001
Cdd:smart00572  232 GQIHKILGMDPLPSM 246
DZF pfam07528
DZF domain; The function of this domain is unknown. It is often found associated with ...
 753-999 1.36e-74

DZF domain; The function of this domain is unknown. It is often found associated with pfam00098 or pfam00035. This domain has been predicted to belong to the nucleotidyltransferase superfamily.


Pssm-ID: 284860  Cd Length: 248  Bit Score: 246.33  E-value: 1.36e-74
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   753 RVGVLAKGLLLRGDRNVNLVLLCSEKPSKSLLSRIAENLPKQLAVISPekyDIKCAVSEAAIILNSCVEPKMQVTITLTS 832
Cdd:pfam07528    1 QVGSFKKGTLLKGSNVADVVVILKTLPTTELVDALAKKVEEDLKTSMK---TEILQSVEALIVIKNTKEPPLELGFHITS 77

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   833 PIIRE--------ENMRegdvtsgmVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTWSD 904
Cdd:pfam07528   78 PVAKVrmliatlpENLR--------KLEPEDHLDRKKMQSHLASIRHTRWFEENAHHLKSIKVLIRVLKDLCRRFDTFGP 149

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578   905 FPSWAMELLVEKAISSASSPQS--PGDALRRVFECISSGIILKGSPGLLDPCEKDPFDTLATMTDQQREDITSSAQFALR 982
Cdd:pfam07528  150 LSGWPLDLLAHKAIMNNPSRQAlpAGEAFRRVFELLASGIFLPGSAGITDPCEKGHTRVHTHLTLQQQDDCCMTAQTLLR 229

                          250
                   ....*....|....*..
gi 564335578   983 LLAFRQIHKVLGMDPLP 999
Cdd:pfam07528  230 VLAHGGYKHILGMDGNT 246
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 544-575 8.27e-08

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 49.17  E-value: 8.27e-08
                            10        20        30
                    ....*....|....*....|....*....|..
gi 564335578    544 RFHCKLCECSFNDPNAKEMHLKGRRHRLQYKK 575
Cdd:smart00451    3 GFYCKLCNVTFTDEISVEAHLKGKKHKKNVKK 34
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 294-323 6.35e-07

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 46.48  E-value: 6.35e-07
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    294 HYCDVCKISCAGPQTYKEHLEGQKHKKKEA 323
Cdd:smart00451    4 FYCKLCNVTFTDEISVEAHLKGKKHKKNVK 33
ZnF_U1 smart00451
U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ...
 347-376 7.08e-06

U1-like zinc finger; Family of C2H2-type zinc fingers, present in matrin, U1 small nuclear ribonucleoprotein C and other RNA-binding proteins.


Pssm-ID: 197732 [Multi-domain]  Cd Length: 35  Bit Score: 43.78  E-value: 7.08e-06
                            10        20        30
                    ....*....|....*....|....*....|
gi 564335578    347 CELCDVSCTGADAYAAHIRGAKHQKVVKLH 376
Cdd:smart00451    6 CKLCNVTFTDEISVEAHLKGKKHKKNVKKR 35
PHA03255 PHA03255
BDLF3; Provisional
 345-514 1.23e-05

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 47.98  E-value: 1.23e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  345 LRCE--LCDVSCTGADAYAAHIRGAkhqkvvklhTKLGKPIPSTEPNVVSQATSSTAVSASKPTaspSSIGASNCTLNTS 422
Cdd:PHA03255   16 LICEtsLIWTSSGSSTASAGNVTGT---------TAVTTPSPSASGPSTNQSTTLTTTSAPITT---TAILSTNTTTVTS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564335578  423 SiaTTSVKGLSTTGN-SSLNSTSNTKVSAVPTNMAAKKTSTPKINfvgGNKLQSTGNKAEDLKGTDCIKNNPAASAVQIP 501
Cdd:PHA03255   84 T--GTTVTPVPTTSNaSTINVTTKVTAQNITATEAGTGTSTGVTS---NVTTRSSSTTSATTRITNATTLAPTLSSKGTS 158

                         170
                  ....*....|...
gi 564335578  502 EVKQDAVSEPVTP 514
Cdd:PHA03255  159 NATKTTAELPTVP 171
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 545-569 6.47e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.56  E-value: 6.47e-05
                           10        20
                   ....*....|....*....|....*
gi 564335578   545 FHCKLCECSFNDPNAKEMHLKGRRH 569
Cdd:pfam12874    1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 295-318 7.42e-05

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 40.56  E-value: 7.42e-05
                           10        20
                   ....*....|....*....|....
gi 564335578   295 YCDVCKISCAGPQTYKEHLEGQKH 318
Cdd:pfam12874    2 YCELCNVTFNSESQLKSHLQGKKH 25
zf-met pfam12874
Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found ...
 345-369 2.36e-04

Zinc-finger of C2H2 type; This is a zinc-finger domain with the CxxCx(12)Hx(6)H motif, found in multiple copies in a wide range of proteins from plants to metazoans. Some member proteins, particularly those from plants, are annotated as being RNA-binding.


Pssm-ID: 463736 [Multi-domain]  Cd Length: 25  Bit Score: 39.02  E-value: 2.36e-04
                           10        20
                   ....*....|....*....|....*
gi 564335578   345 LRCELCDVSCTGADAYAAHIRGAKH 369
Cdd:pfam12874    1 FYCELCNVTFNSESQLKSHLQGKKH 25
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 544-570 2.87e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.99  E-value: 2.87e-03
                           10        20
                   ....*....|....*....|....*..
gi 564335578   544 RFHCKLCECSFNDPNAKEMHLKGRRHR 570
Cdd:pfam12171    1 QFYCVLCDKYFKSENALQNHLKSKKHK 27
zf-C2H2_jaz pfam12171
Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, ...
 294-319 3.10e-03

Zinc-finger double-stranded RNA-binding; This domain family is found in archaea and eukaryotes, and is approximately 30 amino acids in length. The mammalian members of this group occur multiple times along the protein, joined by flexible linkers, and are referred to as JAZ - dsRNA-binding ZF protein - zinc-fingers. The JAZ proteins are expressed in all tissues tested and localize in the nucleus, particularly the nucleolus. JAZ preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids rather than DNA. In addition to binding double-stranded RNA, these zinc-fingers are required for nucleolar localization.


Pssm-ID: 432381 [Multi-domain]  Cd Length: 27  Bit Score: 35.99  E-value: 3.10e-03
                           10        20
                   ....*....|....*....|....*.
gi 564335578   294 HYCDVCKISCAGPQTYKEHLEGQKHK 319
Cdd:pfam12171    2 FYCVLCDKYFKSENALQNHLKSKKHK 27
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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