NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|564330225|ref|XP_006230004|]
View 

protocadherin-16 isoform X1 [Rattus norvegicus]

Protein Classification

cadherin repeat domain-containing protein( domain architecture ID 10182789)

cadherin repeat domain-containing protein similar to cadherins, which are calcium-dependent cell adhesion proteins that preferentially interact with themselves in connecting cells

CATH:  2.60.40.60
Gene Ontology:  GO:0007156|GO:0005509
PubMed:  28268172
SCOP:  4007535

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 1.36e-37

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 137.44  E-value: 1.36e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1108 VAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 564330225 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 2.32e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 133.98  E-value: 2.32e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.22e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.22e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  476 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 564330225  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 4.69e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.43  E-value: 4.69e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 1.71e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.81  E-value: 1.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1852 SYSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 564330225 1931 GPLSTTVPITVTVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 4.38e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.65  E-value: 4.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1544 RMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 564330225 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 6.21e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 6.21e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAG- 2677
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                          90
                  ....*....|....*...
gi 564330225 2678 THFALVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 3.67e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.67e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 564330225 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 8.21e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 8.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2479 HYRVAVSEDLPPGSTLLTLEAIDADgSRSHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 564330225 2559 TQYNLTVTAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.23e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.23e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 564330225  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.19e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 564330225  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 1.49e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.86  E-value: 1.49e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 564330225 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 1.64e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 564330225 2452 APGRSAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 4.21e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.21e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  788 QYVFSVPEDVAPGTSVGVVQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 564330225  866 PPVFSAARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 4.87e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 564330225 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 3.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.23  E-value: 3.82e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2705 STSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 564330225 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 5.80e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGTITVqsAEGLDFETNPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITT--AKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  894 TVLLPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 564330225  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 8.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 8.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  144 LQIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 564330225  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.06e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 564330225  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.43e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.22  E-value: 2.43e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 1.37e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.91  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 564330225 1075 elGQQTGTATVRVVILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 7.81e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.60  E-value: 7.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1438 LPENPEPGATLYTFRASDADGpGPNSDVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLIVEATDrpaNASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD---GGGP 80

                          90
                  ....*....|....*...
gi 564330225 1518 RKATRVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 1.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtatsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 564330225 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 4.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.42  E-value: 4.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 564330225  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 3.52e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


:

Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspaalgPRDR------VLFIVATDLGRPARSATGVVI 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 564330225 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1427 4.66e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


:

Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 55.43  E-value: 4.66e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564330225   1356 GVLTYTLVGGaDPEGTFALDSASGRLYLARVLDFESGPAWRaLTVRAEGPGGAGAR-LMRVQVRVQDENEHAP 1427
Cdd:smart00112   11 GKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSsTATVTITVLDVNDNAP 81
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 1.36e-37

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 137.44  E-value: 1.36e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1108 VAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 564330225 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 2.32e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 133.98  E-value: 2.32e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.22e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.22e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  476 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 564330225  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 4.69e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.43  E-value: 4.69e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 1.71e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.81  E-value: 1.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1852 SYSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 564330225 1931 GPLSTTVPITVTVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 4.38e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.65  E-value: 4.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1544 RMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 564330225 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 6.21e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 6.21e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAG- 2677
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                          90
                  ....*....|....*...
gi 564330225 2678 THFALVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 3.67e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.67e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 564330225 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 8.21e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 8.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2479 HYRVAVSEDLPPGSTLLTLEAIDADgSRSHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 564330225 2559 TQYNLTVTAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 490-570 1.47e-29

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 113.98  E-value: 1.47e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    490 TARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNE 569
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225    570 P 570
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.23e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.23e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 564330225  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.19e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 564330225  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1108-1196 3.17e-27

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 107.77  E-value: 3.17e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1108 VAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDsKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSA 1187
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG-GNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 564330225  1188 TGTVHVAVL 1196
Cdd:pfam00028   84 TATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1123-1203 3.94e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 107.05  E-value: 3.94e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1123 ATDKDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSATGTVHVAVLDLNDNS 1202
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1203 P 1203
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1766-1846 5.28e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 106.66  E-value: 5.28e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1766 RASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDHA 1845
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1846 P 1846
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 1.49e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.86  E-value: 1.49e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 564330225 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1665-1742 2.95e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 104.35  E-value: 2.95e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1665 KATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPPLLTHITVRVTVEDENDHS 1741
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1742 P 1742
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1545-1632 6.21e-26

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 103.92  E-value: 6.21e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1545 MRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPRS 1623
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82


                   ....*....
gi 564330225  1624 STQLLTVSV 1632
Cdd:pfam00028   83 STATVTITV 91
Cadherin pfam00028
Cadherin domain;
1647-1735 1.02e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 103.15  E-value: 1.02e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1647 YNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPP 1723
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225  1724 LLTHITVRVTVE 1735
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1561-1640 1.26e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.81  E-value: 1.26e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1561 VARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSSTQLLTVSVVDVNDEA 1639
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1640 P 1640
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 1.64e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 564330225 2452 APGRSAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 273-354 2.21e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 98.96  E-value: 2.21e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    273 ASDADAGANGAVTYEINrrQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDN 352
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 564330225    353 QP 354
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 4.21e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.21e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  788 QYVFSVPEDVAPGTSVGVVQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 564330225  866 PPVFSAARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 4.87e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 564330225 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
476-560 1.27e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 97.37  E-value: 1.27e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   476 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*
gi 564330225   556 ATVSV 560
Cdd:pfam00028   85 ATVTI 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 3.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.23  E-value: 3.82e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2705 STSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 564330225 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 5.80e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGTITVqsAEGLDFETNPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITT--AKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1853-1943 6.94e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 95.06  E-value: 6.94e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1853 YSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYY-LGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDgAAAG 1931
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD-SGGP 79

                           90
                   ....*....|..
gi 564330225  1932 PLSTTVPITVTV 1943
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  894 TVLLPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 564330225  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 8.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 8.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  144 LQIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 564330225  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.06e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 564330225  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
1752-1839 1.10e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 91.98  E-value: 1.10e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1752 EVPEGQDPQT-LTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSA 1830
Cdd:pfam00028    4 SVPENAPVGTeVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 564330225  1831 TLLVTVTVL 1839
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.43e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.22  E-value: 2.43e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2499-2593 5.53e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.53e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2499 AIDADgSRSHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESLTQYNLTVTAADRGQPPRSSA 2578
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET--------------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSST 66

                            90
                    ....*....|....*
gi 564330225   2579 VPVTVTVLDVNDNPP 2593
Cdd:smart00112   67 ATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2619-2697 7.26e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.95  E-value: 7.26e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2619 ASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAG-THFALVPVTVEVQDVNDHGP 2697
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1871-1951 1.22e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 1.22e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1871 QAHDPDEGDNGRVMYYL-GAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAAGPLSTTVPITVTVRDVNDH 1949
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 564330225   1950 AP 1951
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 1.37e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.91  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 564330225 1075 elGQQTGTATVRVVILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
254-346 1.53e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.53e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGA 333
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 564330225   334 HPELGSAFVTVHV 346
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 383-464 1.79e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 87.79  E-value: 1.79e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    383 SVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVN 460
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEIT---TTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 564330225    461 DNAP 464
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
1217-1306 2.20e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.13  E-value: 2.20e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1217 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGSGSE-LFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPR 1295
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 564330225  1296 SASLQLLVQVL 1306
Cdd:pfam00028   82 SSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 595-677 5.66e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 5.66e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    595 TATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQGPsSFDFTVTAIDGGG--LKSMVYVKVFVADE 672
Cdd:smart00112    1 SATDADSGENGKVTYSI---LSGNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGppLSSTATVTITVLDV 76


                    ....*
gi 564330225    673 NDNPP 677
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 7.81e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.60  E-value: 7.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1438 LPENPEPGATLYTFRASDADGpGPNSDVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLIVEATDrpaNASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD---GGGP 80

                          90
                  ....*....|....*...
gi 564330225 1518 RKATRVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2600-2690 2.17e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.35  E-value: 2.17e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2600 YRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAGTH 2679
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225  2680 -FALVPVTVEVQ 2690
Cdd:pfam00028   81 lSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2392-2473 6.88e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 6.88e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2392 SATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTVgamALGHEGPGVVDVVLEARDHGAPGRSAQATVHVQLKDQN 2469
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTK---PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 564330225   2470 DHAP 2473
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-247 6.95e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 6.95e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    161 AHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLL 240
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETG-------EITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 564330225    241 DINDHAP 247
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2480-2586 7.40e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 7.40e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2480 YRVAVSEDLPPGSTLLTLEAIDADGSrSHATVDYSIISGNRGRVFQLEPRlaevgDGVgpgpqalgcLVLLEPLDFESLT 2559
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLG-PNGRIFYSILGGGPGGNFRIDPD-----TGD---------ISTTKPLDRESIG 65

                           90       100
                   ....*....|....*....|....*..
gi 564330225  2560 QYNLTVTAADRGQPPRSSAVPVTVTVL 2586
Cdd:pfam00028   66 EYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
684-774 9.20e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 9.20e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   684 YAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQ 763
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|.
gi 564330225   764 AEPIARVNISI 774
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2188-2268 1.41e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.00  E-value: 1.41e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2188 ADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2267
Cdd:smart00112    2 ATDADSGENGKVTYSIL-SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   2268 P 2268
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 1.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtatsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 564330225 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1537 3.04e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 3.04e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1452 RASDADGpGPNSDVRYRLLRQEPPVPaLRLDARTGALSAPRGLDRETTPALLLIVEATDrpaNASRRKATRVSARVFVTD 1531
Cdd:smart00112    1 SATDADS-GENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATD---GGGPPLSSTATVTITVLD 75


                    ....*.
gi 564330225   1532 ENDNAP 1537
Cdd:smart00112   76 VNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2090-2162 3.39e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 3.39e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564330225   2090 GSNGPITYSILSGNERGIFSIQPSTGTITVQSAegLDFETNPRLRLVLQAESGGAFAFSV---LTLTLQDANDNAP 2162
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSStatVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
897-983 3.93e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.19  E-value: 3.93e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   897 LPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPRTSH 975
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 564330225   976 FRLRVVIQ 983
Cdd:pfam00028   85 ATVTITVL 92
Cadherin pfam00028
Cadherin domain;
368-457 6.39e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.41  E-value: 6.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDIS---TTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225   446 LRAEAAFVLHVT 457
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2705-2797 9.07e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 9.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2705 STSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLEavpGPEGReAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG---GGPGG-NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 564330225  2785 --NLSASVTVSVLIT 2797
Cdd:pfam00028   78 gpPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2295-2367 1.42e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.42e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564330225   2295 DVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEGHANLTVLVEDVNDNVP 2367
Cdd:smart00112    4 DADSGEngKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1234-1306 3.03e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.15  E-value: 3.03e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564330225   1234 QAKDPDEGENGTILYTLT-GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1306
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
2067-2155 1.89e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.18  E-value: 1.89e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2067 EAVLRENAPPGTPVISPKAVHS-GGSNGPITYSILSGNERGIFSIQPSTGTITVQSAegLDFETNPRLRLVLQAESGGAF 2145
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|.
gi 564330225  2146 A-FSVLTLTLQ 2155
Cdd:pfam00028   80 PlSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
2374-2465 2.51e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.79  E-value: 2.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTvgaMALGHEGPGVVDVVLEARDHG 2451
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 564330225  2452 APGRSAQATVHVQL 2465
Cdd:pfam00028   78 GPPLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 4.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.42  E-value: 4.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 564330225  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
577-658 5.80e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.80e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQgPSSFDFTVTAIDG 656
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI---LGGGPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDS 76


                   ..
gi 564330225   657 GG 658
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
999-1090 6.46e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 6.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   999 YRVDLPSGTTTGTQILQVQAQAPDGSP---VTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKae 1075
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-- 78

                           90
                   ....*....|....*
gi 564330225  1076 lGQQTGTATVRVVIL 1090
Cdd:pfam00028   79 -PPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2169-2261 1.51e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2169 YVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSP 2248
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIL-GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 564330225  2249 ALVGSATLTVMVI 2261
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1020-1097 2.54e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.76  E-value: 2.54e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564330225   1020 APDGSPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKAELgqqTGTATVRVVILNQNDHSP 1097
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPL---SSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 813-886 3.27e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.37  E-value: 3.27e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564330225    813 GRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRElLGPVLELEVRA-GSGTPPVFSAARIRVLLDDVNDNSP 886
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 911-984 1.12e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 1.12e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564330225    911 RALDPDSGANSRVTFSLLAGGD-GLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPRTSHFRLRVVIQD 984
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLD 75
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 702-775 1.43e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.43e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564330225    702 HAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQAEPIARVNISIV 775
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2722-2801 1.50e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.50e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2722 HAMDGDAGTFGRLRYTLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDE 2801
Cdd:smart00112    1 SATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
Cadherin pfam00028
Cadherin domain;
2277-2360 2.03e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2277 RVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEG 2351
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPngRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSggpPLSS 83


                   ....*....
gi 564330225  2352 HANLTVLVE 2360
Cdd:pfam00028   84 TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
789-878 3.44e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   789 YVFSVPEDVAPGTSVGVVQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLGPVlELEVRA-GSGTP 866
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEY-ELTVEAtDSGGP 79

                           90
                   ....*....|..
gi 564330225   867 PVFSAARIRVLL 878
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 3.52e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspaalgPRDR------VLFIVATDLGRPARSATGVVI 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 564330225 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
Cadherin pfam00028
Cadherin domain;
145-240 4.06e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 4.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   145 QIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDG 224
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*.
gi 564330225   225 GSPPRRAQALLDVTLL 240
Cdd:pfam00028   77 GGPPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 72-135 5.98e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.83  E-value: 5.98e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225     72 YFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAV------TPDGATVEVTVRVADINDHAP 135
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEatdgggPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2811-2916 9.74e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 9.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2811 FHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYLRvdsrapgsgtatsgggGRTRREAP 2888
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT----------------KPLDRESI 64

                           90       100
                   ....*....|....*....|....*...
gi 564330225  2889 RELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:pfam00028   65 GEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1976-2049 2.23e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.62  E-value: 2.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspaalgPRDR------VLFIVATDLGRPARSATGVVI 2048
Cdd:pfam00028   15 VLTVTATDPDLGPNGRIFYSILGGGPGGNfRIDPDTGDISTTK------PLDResigeyELTVEATDSGGPPLSSTATVT 88


                   .
gi 564330225  2049 V 2049
Cdd:pfam00028   89 I 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1427 4.66e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 55.43  E-value: 4.66e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564330225   1356 GVLTYTLVGGaDPEGTFALDSASGRLYLARVLDFESGPAWRaLTVRAEGPGGAGAR-LMRVQVRVQDENEHAP 1427
Cdd:smart00112   11 GKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSsTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1980-2052 2.72e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 2.72e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1980 RAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARSPaalgprDR------VLFIVATDLGRPARSATGVVIVGIQ 2052
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPL------DReeqpeyTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
44-127 3.13e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 50.76  E-value: 3.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    44 QIDEEQPAGTLIGDISAG---LPPGTAPppMYFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAV------ 114
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATdpdLGPNGRI--FYSILGGGPGGN---FRIDPDTGDISTTKPLDRESIGEYELTVEatdsgg 78

                           90
                   ....*....|...
gi 564330225   115 TPDGATVEVTVRV 127
Cdd:pfam00028   79 PPLSSTATVTITV 91
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 1224-1642 7.22e-06

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 52.18  E-value: 7.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1224 VPPGTLVTTLQAKDPDEGENGTILYTLTGSGSELFSLHPHTGELHTA------ASLIRAERPHYVltlsahdqgSPP--- 1294
Cdd:COG3321   797 VGPGPVLTGLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAgvpvdwSALYPGRGRRRV---------PLPtyp 867

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1295 ---RSASLQLLVQVLPSTRMVESPDLVEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEPASMGVLTYTLVGGADPEGT 1371
Cdd:COG3321   868 fqrEDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAA 947

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1372 FALDSASGRLYLARVLDFESGPAWRALTVRAEGPGGAGARLMRVQVRVQDENEHAPAFARDPLALALPENPEPGATLYTF 1451
Cdd:COG3321   948 AAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAAL 1027

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1452 RASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLIVEATDRPANASRRKATRVSARVFVTD 1531
Cdd:COG3321  1028 LAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALL 1107

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1532 ENDNAPVFASPSRMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGDGHFRLHATTGALSVVRPLDREQRAEHVLT 1611
Cdd:COG3321  1108 LLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAA 1187

                         410       420       430
                  ....*....|....*....|....*....|.
gi 564330225 1612 VVASDHGSPPRSSTQLLTVSVVDVNDEAPAF 1642
Cdd:COG3321  1188 ALAGLAALLLAALLAALLAALLALALAALAA 1218
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2829-2916 1.81e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 45.42  E-value: 1.81e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2829 QATDEDGGADGLVLYSLATSSP--YFGINQTTGALYL--RVDsrapgsgtatsggggrtrREAPRELRLEVVARGPLPGS 2904
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTtkPLD------------------REEQPEYTLTVEATDGGGPP 62

                            90
                    ....*....|..
gi 564330225   2905 RSATVPVTVDIT 2916
Cdd:smart00112   63 LSSTATVTITVL 74
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1609-1948 1.99e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 50.81  E-value: 1.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1609 VLTVVASDhgSPPRSSTQLLTVSVVDVNDE--APAFPQQEYNvilrENSppgTSLLTLKATDPDlgaNGQVTYG--GVSG 1684
Cdd:NF038112 1255 TFQLVVSD--GTKTSAPDTVTVLVRNVNRApvAVAGAPATVD----ERS---TVTLDGSGTDAD---GDALTYAwtQTSG 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1685 ESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPpllTHITVRVTVEDENdHSPTfGNTHLSLEVPEGqDPQTLTT 1764
Cdd:NF038112 1323 PAVTLTGATTATATFTAPEVTADTQLTFTLTVSDGTAS---ATDTVTVTVRNVN-RAPV-ANAGADQTVDER-STVTLSG 1396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1765 lRASDPDGGlngQLQYRilgGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDH 1844
Cdd:NF038112 1397 -SATDPDGD---ALTYA---WTQTAGPTVTLTGADTATASFTAPEVAADTELTFQLTVSADGQASADVTVTVTVRNVNRA 1469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1845 APAFPVPSYSVEvpEDAPVGtllLQLQAHDPDegdnGRVMYYLGAGTAG-AFLLEPTSGELSTATALDREHCASYAFSVT 1923
Cdd:NF038112 1470 PVAHAGESITVD--EGSTVT---LDASATDPD----GDTLTYAWTQVAGpSVTLTGADSAKLTFTAPEVSADTTLTFSLT 1540

                         330       340
                  ....*....|....*....|....*
gi 564330225 1924 AVDGAAAgplSTTVPITVTVRDVND 1948
Cdd:NF038112 1541 VTDGSGS---SGPVVVTVTVKNVNR 1562
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1729-1951 1.37e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 44.65  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1729 TVRVTVEDENdHSPTfGNTHLSLEVPEGqDPQTLTTlRASDPDGGLNGQLqYRILGGDPsgafaLDLTSGEFGTTRPLDR 1808
Cdd:NF038112 1271 TVTVLVRNVN-RAPV-AVAGAPATVDER-STVTLDG-SGTDADGDALTYA-WTQTSGPA-----VTLTGATTATATFTAP 1340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1809 EVEPAFQL--QIEARDGGQpalSATLLVTVTVLDANDHapafPVPSYSVEVPEDAPvGTLLLQLQAHDPDegdnGRVMYY 1886
Cdd:NF038112 1341 EVTADTQLtfTLTVSDGTA---SATDTVTVTVRNVNRA----PVANAGADQTVDER-STVTLSGSATDPD----GDALTY 1408

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564330225 1887 LGAGTAG-AFLLEPTSGELSTATALDREHCASYAFSVTAvdgAAAGPLSTTVPITVTVRDVNdHAP 1951
Cdd:NF038112 1409 AWTQTAGpTVTLTGADTATASFTAPEVAADTELTFQLTV---SADGQASADVTVTVTVRNVN-RAP 1470
 
Name Accession Description Interval E-value
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1108-1201 1.36e-37

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 137.44  E-value: 1.36e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1108 VAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSA 1187
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGL-FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSS 84

                          90
                  ....*....|....
gi 564330225 1188 TGTVHVAVLDLNDN 1201
Cdd:cd11304    85 TATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1646-1740 2.32e-36

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 133.98  E-value: 2.32e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1646 EYNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLP 1722
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYsivSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 1723 PLLTHITVRVTVEDENDH 1740
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 476-568 1.22e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 128.97  E-value: 1.22e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  476 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLSST 85

                          90
                  ....*....|...
gi 564330225  556 ATVSVALQDVNDN 568
Cdd:cd11304    86 ATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 254-352 4.69e-34

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 127.43  E-value: 4.69e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGA 333
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI--VSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225  334 HPELGSAFVTVHVRDANDN 352
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1852-1949 1.71e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 122.81  E-value: 1.71e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1852 SYSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYYLGAGTA-GAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAA 1930
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDG-GG 79

                          90
                  ....*....|....*....
gi 564330225 1931 GPLSTTVPITVTVRDVNDH 1949
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1544-1637 4.38e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.65  E-value: 4.38e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1544 RMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPR 1622
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*
gi 564330225 1623 SSTQLLTVSVVDVND 1637
Cdd:cd11304    83 SSTATVTITVLDVND 97
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2599-2695 6.21e-32

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 121.27  E-value: 6.21e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2599 SYRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAG- 2677
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGp 80

                          90
                  ....*....|....*...
gi 564330225 2678 THFALVPVTVEVQDVNDH 2695
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1750-1844 3.67e-31

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 118.96  E-value: 3.67e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1750 SLEVPEGQDP-QTLTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPAL 1828
Cdd:cd11304     3 EVSVPENAPPgTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|....*.
gi 564330225 1829 SATLLVTVTVLDANDH 1844
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2479-2591 8.21e-30

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 115.10  E-value: 8.21e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2479 HYRVAVSEDLPPGSTLLTLEAIDADgSRSHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESL 2558
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPD-SGENGEVTYSIVSGNEDGLFSIDPST--------------GEITTAKPLDREEQ 65

                          90       100       110
                  ....*....|....*....|....*....|...
gi 564330225 2559 TQYNLTVTAADRGQPPRSSAVPVTVTVLDVNDN 2591
Cdd:cd11304    66 SSYTLTVTATDGGGPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 490-570 1.47e-29

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 113.98  E-value: 1.47e-29
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    490 TARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNE 569
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225    570 P 570
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 577-675 3.23e-28

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 110.48  E-value: 3.23e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQgPSSFDFTVTAIDG 656
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSI---VSGNEDGLFSIDPSTGEITTAKPLDREE-QSSYTLTVTATDG 77

                          90       100
                  ....*....|....*....|.
gi 564330225  657 GG--LKSMVYVKVFVADENDN 675
Cdd:cd11304    78 GGppLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 368-462 2.19e-27

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 108.17  E-value: 2.19e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGG--EGHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:cd11304     5 SVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGneDGLFSIDPSTGEIT---TAKPLDREEQSSYTLTVTATDGGGPP 81

                          90
                  ....*....|....*..
gi 564330225  446 LRAEAAFVLHVTDVNDN 462
Cdd:cd11304    82 LSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1108-1196 3.17e-27

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 107.77  E-value: 3.17e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1108 VAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDsKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSA 1187
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPG-GNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 564330225  1188 TGTVHVAVL 1196
Cdd:pfam00028   84 TATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1123-1203 3.94e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 107.05  E-value: 3.94e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1123 ATDKDSGPNGRLTYSLQQLSEDSKaFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSATGTVHVAVLDLNDNS 1202
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1203 P 1203
Cdd:smart00112   81 P 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1766-1846 5.28e-27

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 106.66  E-value: 5.28e-27
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1766 RASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDHA 1845
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1846 P 1846
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1218-1306 1.49e-26

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 105.86  E-value: 1.49e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1218 IQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT-GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRS 1296
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVsGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPLS 83

                          90
                  ....*....|
gi 564330225 1297 ASLQLLVQVL 1306
Cdd:cd11304    84 STATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1665-1742 2.95e-26

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 104.35  E-value: 2.95e-26
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1665 KATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPPLLTHITVRVTVEDENDHS 1741
Cdd:smart00112    1 SATDADSGENGKVTYsilSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1742 P 1742
Cdd:smart00112   81 P 81
Cadherin pfam00028
Cadherin domain;
1545-1632 6.21e-26

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 103.92  E-value: 6.21e-26
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1545 MRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGG-DGHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPRS 1623
Cdd:pfam00028    3 ASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLS 82


                   ....*....
gi 564330225  1624 STQLLTVSV 1632
Cdd:pfam00028   83 STATVTITV 91
Cadherin pfam00028
Cadherin domain;
1647-1735 1.02e-25

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 103.15  E-value: 1.02e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1647 YNVILRENSPPGTSLLTLKATDPDLGANGQVTY---GGVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPP 1723
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYsilGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225  1724 LLTHITVRVTVE 1735
Cdd:pfam00028   81 LSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1561-1640 1.26e-25

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 102.81  E-value: 1.26e-25
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1561 VARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSSTQLLTVSVVDVNDEA 1639
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   1640 P 1640
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2374-2471 1.64e-25

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 102.78  E-value: 1.64e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTVgamALGHEGPGVVDVVLEARDHG 2451
Cdd:cd11304     2 YEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDglFSIDPSTGEITTAK---PLDREEQSSYTLTVTATDGG 78

                          90       100
                  ....*....|....*....|
gi 564330225 2452 APGRSAQATVHVQLKDQNDH 2471
Cdd:cd11304    79 GPPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 273-354 2.21e-24

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 98.96  E-value: 2.21e-24
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    273 ASDADAGANGAVTYEINrrQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDN 352
Cdd:smart00112    2 ATDADSGENGKVTYSIL--SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDN 79


                    ..
gi 564330225    353 QP 354
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 788-884 4.21e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.21e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  788 QYVFSVPEDVAPGTSVGVVQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLgPVLELEVRA-GSGT 865
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPdSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQ-SSYTLTVTAtDGGG 79

                          90
                  ....*....|....*....
gi 564330225  866 PPVFSAARIRVLLDDVNDN 884
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2275-2365 4.87e-24

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 98.92  E-value: 4.87e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2275 ELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PH 2349
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGEngEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggpPL 82

                          90
                  ....*....|....*.
gi 564330225 2350 EGHANLTVLVEDVNDN 2365
Cdd:cd11304    83 SSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
476-560 1.27e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 97.37  E-value: 1.27e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   476 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSS 555
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*
gi 564330225   556 ATVSV 560
Cdd:pfam00028   85 ATVTI 89
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2705-2801 3.82e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 96.23  E-value: 3.82e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2705 STSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV----SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGG 78

                          90
                  ....*....|....*..
gi 564330225 2785 NLSASVTVSVLITGEDE 2801
Cdd:cd11304    79 GPPLSSTATVTITVLDV 95
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2067-2160 5.80e-23

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 95.84  E-value: 5.80e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2067 EAVLRENAPPGTPVISPKAV-HSGGSNGPITYSILSGNERGIFSIQPSTGTITVqsAEGLDFETNPRLRLVLQAESGGAF 2145
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATdPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITT--AKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|....*...
gi 564330225 2146 AFSV---LTLTLQDANDN 2160
Cdd:cd11304    81 PLSStatVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
1853-1943 6.94e-23

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 95.06  E-value: 6.94e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1853 YSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYY-LGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDgAAAG 1931
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSiLGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATD-SGGP 79

                           90
                   ....*....|..
gi 564330225  1932 PLSTTVPITVTV 1943
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 894-984 1.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 94.69  E-value: 1.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  894 TVLLPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPR 972
Cdd:cd11304     3 EVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNeDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGPPL 82

                          90
                  ....*....|..
gi 564330225  973 TSHFRLRVVIQD 984
Cdd:cd11304    83 SSTATVTITVLD 94
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 144-245 8.49e-22

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 92.38  E-value: 8.49e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  144 LQIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYD 223
Cdd:cd11304     4 VSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTG-------EITTAKPLDREEQSSYTLTVTATD 76

                          90       100
                  ....*....|....*....|..
gi 564330225  224 GGSPPRRAQALLDVTLLDINDH 245
Cdd:cd11304    77 GGGPPLSSTATVTITVLDVNDN 98
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 683-775 1.06e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.99  E-value: 1.06e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  683 EYAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGL 762
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGGP 80

                          90
                  ....*....|...
gi 564330225  763 QAEPIARVNISIV 775
Cdd:cd11304    81 PLSSTATVTITVL 93
Cadherin pfam00028
Cadherin domain;
1752-1839 1.10e-21

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 91.98  E-value: 1.10e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1752 EVPEGQDPQT-LTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSA 1830
Cdd:pfam00028    4 SVPENAPVGTeVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSS 83


                   ....*....
gi 564330225  1831 TLLVTVTVL 1839
Cdd:pfam00028   84 TATVTITVL 92
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2168-2266 2.43e-21

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 91.22  E-value: 2.43e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2168 HYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGS 2247
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIV-SGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG 79

                          90
                  ....*....|....*....
gi 564330225 2248 PALVGSATLTVMVIDTNDN 2266
Cdd:cd11304    80 PPLSSTATVTITVLDVNDN 98
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2499-2593 5.53e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 89.33  E-value: 5.53e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2499 AIDADgSRSHATVDYSIISGNRGRVFQLEPRLaevgdgvgpgpqalGCLVLLEPLDFESLTQYNLTVTAADRGQPPRSSA 2578
Cdd:smart00112    2 ATDAD-SGENGKVTYSILSGNDDGLFSIDPET--------------GEITTTKPLDREEQPEYTLTVEATDGGGPPLSST 66

                            90
                    ....*....|....*
gi 564330225   2579 VPVTVTVLDVNDNPP 2593
Cdd:smart00112   67 ATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2619-2697 7.26e-21

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.95  E-value: 7.26e-21
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2619 ASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAG-THFALVPVTVEVQDVNDHGP 2697
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1871-1951 1.22e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 88.56  E-value: 1.22e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1871 QAHDPDEGDNGRVMYYL-GAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGaAAGPLSTTVPITVTVRDVNDH 1949
Cdd:smart00112    1 SATDADSGENGKVTYSIlSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDG-GGPPLSSTATVTITVLDVNDN 79


                    ..
gi 564330225   1950 AP 1951
Cdd:smart00112   80 AP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 998-1095 1.37e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 88.91  E-value: 1.37e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  998 TYRVDLPSGTTTGTQILQVQAQAPDG---SPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKa 1074
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSgenGEVTYSIVSGNEDGLFSIDPSTGEITTAKPLDREEQSSYTLTVTATDGGG- 79

                          90       100
                  ....*....|....*....|.
gi 564330225 1075 elGQQTGTATVRVVILNQNDH 1095
Cdd:cd11304    80 --PPLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
254-346 1.53e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.51  E-value: 1.53e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   254 YHAVVSESLAPGSPVLQVFASDADAGANGAVTYEInrRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGA 333
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI--LGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG 78

                           90
                   ....*....|...
gi 564330225   334 HPELGSAFVTVHV 346
Cdd:pfam00028   79 PPLSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 383-464 1.79e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 87.79  E-value: 1.79e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    383 SVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVN 460
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNddGLFSIDPETGEIT---TTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 564330225    461 DNAP 464
Cdd:smart00112   78 DNAP 81
Cadherin pfam00028
Cadherin domain;
1217-1306 2.20e-20

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 88.13  E-value: 2.20e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1217 PIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGSGSE-LFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPR 1295
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPL 81

                           90
                   ....*....|.
gi 564330225  1296 SASLQLLVQVL 1306
Cdd:pfam00028   82 SSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 595-677 5.66e-20

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 86.63  E-value: 5.66e-20
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    595 TATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQGPsSFDFTVTAIDGGG--LKSMVYVKVFVADE 672
Cdd:smart00112    1 SATDADSGENGKVTYSI---LSGNDDGLFSIDPETGEITTTKPLDREEQP-EYTLTVEATDGGGppLSSTATVTITVLDV 76


                    ....*
gi 564330225    673 NDNPP 677
Cdd:smart00112   77 NDNAP 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1438-1535 7.81e-20

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 86.60  E-value: 7.81e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1438 LPENPEPGATLYTFRASDADGpGPNSDVRYRLLRQEPPvPALRLDARTGALSAPRGLDRETTPALLLIVEATDrpaNASR 1517
Cdd:cd11304     6 VPENAPPGTVVLTVSATDPDS-GENGEVTYSIVSGNED-GLFSIDPSTGEITTAKPLDREEQSSYTLTVTATD---GGGP 80

                          90
                  ....*....|....*...
gi 564330225 1518 RKATRVSARVFVTDENDN 1535
Cdd:cd11304    81 PLSSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
2600-2690 2.17e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 82.35  E-value: 2.17e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2600 YRVTVPEDMPVGAELLHVEASDADPGPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAGTH 2679
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225  2680 -FALVPVTVEVQ 2690
Cdd:pfam00028   81 lSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2392-2473 6.88e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 6.88e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2392 SATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTVgamALGHEGPGVVDVVLEARDHGAPGRSAQATVHVQLKDQN 2469
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDglFSIDPETGEITTTK---PLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVN 77


                    ....
gi 564330225   2470 DHAP 2473
Cdd:smart00112   78 DNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 161-247 6.95e-18

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 80.47  E-value: 6.95e-18
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    161 AHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLL 240
Cdd:smart00112    2 ATDADSGENGKVTYSILSGNDDGLFSIDPETG-------EITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74


                    ....*..
gi 564330225    241 DINDHAP 247
Cdd:smart00112   75 DVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2480-2586 7.40e-18

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 80.81  E-value: 7.40e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2480 YRVAVSEDLPPGSTLLTLEAIDADGSrSHATVDYSIISGNRGRVFQLEPRlaevgDGVgpgpqalgcLVLLEPLDFESLT 2559
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLG-PNGRIFYSILGGGPGGNFRIDPD-----TGD---------ISTTKPLDRESIG 65

                           90       100
                   ....*....|....*....|....*..
gi 564330225  2560 QYNLTVTAADRGQPPRSSAVPVTVTVL 2586
Cdd:pfam00028   66 EYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
684-774 9.20e-17

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 77.73  E-value: 9.20e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   684 YAASLSAQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQ 763
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|.
gi 564330225   764 AEPIARVNISI 774
Cdd:pfam00028   81 LSSTATVTITV 91
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2188-2268 1.41e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 77.00  E-value: 1.41e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2188 ADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2267
Cdd:smart00112    2 ATDADSGENGKVTYSIL-SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDVNDNA 80


                    .
gi 564330225   2268 P 2268
Cdd:smart00112   81 P 81
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2810-2916 1.80e-16

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 77.35  E-value: 1.80e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 2810 SFHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALYLRV--DsrapgsgtatsggggrtrR 2885
Cdd:cd11304     1 SYEVSVPENAPPGTVVLTVSATDPDSGENGEVTYSIVSGNEdgLFSIDPSTGEITTAKplD------------------R 62

                          90       100       110
                  ....*....|....*....|....*....|.
gi 564330225 2886 EAPRELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:cd11304    63 EEQSSYTLTVTATDGGGPPLSSTATVTITVL 93
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1452-1537 3.04e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 3.04e-16
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1452 RASDADGpGPNSDVRYRLLRQEPPVPaLRLDARTGALSAPRGLDRETTPALLLIVEATDrpaNASRRKATRVSARVFVTD 1531
Cdd:smart00112    1 SATDADS-GENGKVTYSILSGNDDGL-FSIDPETGEITTTKPLDREEQPEYTLTVEATD---GGGPPLSSTATVTITVLD 75


                    ....*.
gi 564330225   1532 ENDNAP 1537
Cdd:smart00112   76 VNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2090-2162 3.39e-16

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 75.85  E-value: 3.39e-16
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564330225   2090 GSNGPITYSILSGNERGIFSIQPSTGTITVQSAegLDFETNPRLRLVLQAESGGAFAFSV---LTLTLQDANDNAP 2162
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKP--LDREEQPEYTLTVEATDGGGPPLSStatVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
897-983 3.93e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 76.19  E-value: 3.93e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   897 LPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGG-DGLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPRTSH 975
Cdd:pfam00028    5 VPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGPPLSST 84


                   ....*...
gi 564330225   976 FRLRVVIQ 983
Cdd:pfam00028   85 ATVTITVL 92
Cadherin pfam00028
Cadherin domain;
368-457 6.39e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.41  E-value: 6.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   368 RVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGE--GHFALSTQDSVIYlvcVARRLDREERDVYNLRVTATDSGSPP 445
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGpgGNFRIDPDTGDIS---TTKPLDRESIGEYELTVEATDSGGPP 80

                           90
                   ....*....|..
gi 564330225   446 LRAEAAFVLHVT 457
Cdd:pfam00028   81 LSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2705-2797 9.07e-16

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 75.03  E-value: 9.07e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2705 STSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLEavpGPEGReAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAG 2784
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILG---GGPGG-NFRIDPDTGDISTTKPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....*
gi 564330225  2785 --NLSASVTVSVLIT 2797
Cdd:pfam00028   78 gpPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2295-2367 1.42e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.92  E-value: 1.42e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564330225   2295 DVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEGHANLTVLVEDVNDNVP 2367
Cdd:smart00112    4 DADSGEngKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGggpPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1234-1306 3.03e-15

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 73.15  E-value: 3.03e-15
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564330225   1234 QAKDPDEGENGTILYTLT-GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1306
Cdd:smart00112    1 SATDADSGENGKVTYSILsGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
2067-2155 1.89e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 71.18  E-value: 1.89e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2067 EAVLRENAPPGTPVISPKAVHS-GGSNGPITYSILSGNERGIFSIQPSTGTITVQSAegLDFETNPRLRLVLQAESGGAF 2145
Cdd:pfam00028    2 SASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKP--LDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|.
gi 564330225  2146 A-FSVLTLTLQ 2155
Cdd:pfam00028   80 PlSSTATVTIT 90
Cadherin pfam00028
Cadherin domain;
2374-2465 2.51e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 70.79  E-value: 2.51e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2374 YQVMMLEHTPPGSAILSVSATDRDSGANGHISYHLASPAEG--FSVDTNNGTLFTTvgaMALGHEGPGVVDVVLEARDHG 2451
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT---KPLDRESIGEYELTVEATDSG 77

                           90
                   ....*....|....
gi 564330225  2452 APGRSAQATVHVQL 2465
Cdd:pfam00028   78 GPPLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 43-133 4.03e-14

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 70.42  E-value: 4.03e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   43 LQIDEEQPAGTLIGDISA-GLPPGTAPPPMYFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAVTPDG--- 118
Cdd:cd11304     4 VSVPENAPPGTVVLTVSAtDPDSGENGEVTYSIVSGNEDGL---FSIDPSTGEITTAKPLDREEQSSYTLTVTATDGggp 80

                          90
                  ....*....|....*...
gi 564330225  119 ---ATVEVTVRVADINDH 133
Cdd:cd11304    81 plsSTATVTITVLDVNDN 98
Cadherin pfam00028
Cadherin domain;
577-658 5.80e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 5.80e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   577 YNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLgagLGASGSPPFRIDAHSGEVCTTRILDRDQgPSSFDFTVTAIDG 656
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSI---LGGGPGGNFRIDPDTGDISTTKPLDRES-IGEYELTVEATDS 76


                   ..
gi 564330225   657 GG 658
Cdd:pfam00028   77 GG 78
Cadherin pfam00028
Cadherin domain;
999-1090 6.46e-14

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 69.64  E-value: 6.46e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   999 YRVDLPSGTTTGTQILQVQAQAPDGSP---VTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKae 1075
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPngrIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGG-- 78

                           90
                   ....*....|....*
gi 564330225  1076 lGQQTGTATVRVVIL 1090
Cdd:pfam00028   79 -PPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
2169-2261 1.51e-13

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 68.48  E-value: 1.51e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2169 YVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAaSQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSP 2248
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSIL-GGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSGGP 79

                           90
                   ....*....|...
gi 564330225  2249 ALVGSATLTVMVI 2261
Cdd:pfam00028   80 PLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1020-1097 2.54e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.76  E-value: 2.54e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 564330225   1020 APDGSPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKAELgqqTGTATVRVVILNQNDHSP 1097
Cdd:smart00112    7 SGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPL---SSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 813-886 3.27e-13

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 67.37  E-value: 3.27e-13
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564330225    813 GRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRElLGPVLELEVRA-GSGTPPVFSAARIRVLLDDVNDNSP 886
Cdd:smart00112    8 GENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDRE-EQPEYTLTVEAtDGGGPPLSSTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 911-984 1.12e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.83  E-value: 1.12e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 564330225    911 RALDPDSGANSRVTFSLLAGGD-GLFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPRTSHFRLRVVIQD 984
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLD 75
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 702-775 1.43e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.43e-12
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 564330225    702 HAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWPLGRRANSVVQLEIGAQDGGGLQAEPIARVNISIV 775
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVL 74
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2722-2801 1.50e-12

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 65.45  E-value: 1.50e-12
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2722 HAMDGDAGTFGRLRYTLLeavpGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDE 2801
Cdd:smart00112    1 SATDADSGENGKVTYSIL----SGNDDGLFSIDPETGEITTTKPLDREEQPEYTLTVEATDGGGPPLSSTATVTITVLDV 76
Cadherin pfam00028
Cadherin domain;
2277-2360 2.03e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 65.40  E-value: 2.03e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2277 RVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDG---PHEG 2351
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPngRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEYELTVEATDSggpPLSS 83


                   ....*....
gi 564330225  2352 HANLTVLVE 2360
Cdd:pfam00028   84 TATVTITVL 92
Cadherin pfam00028
Cadherin domain;
789-878 3.44e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 3.44e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   789 YVFSVPEDVAPGTSVGVVQAHNP-PGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLGPVlELEVRA-GSGTP 866
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPdLGPNGRIFYSILGGGPGGNFRIDPDTGDISTTKPLDRESIGEY-ELTVEAtDSGGP 79

                           90
                   ....*....|..
gi 564330225   867 PVFSAARIRVLL 878
Cdd:pfam00028   80 PLSSTATVTITV 91
Cadherin_repeat cd11304
Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1976-2052 3.52e-12

Cadherin tandem repeat domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers.


Pssm-ID: 206637 [Multi-domain]  Cd Length: 98  Bit Score: 65.03  E-value: 3.52e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspaalgPRDR------VLFIVATDLGRPARSATGVVI 2048
Cdd:cd11304    16 VLTVSATDPDSGENGEVTYSIVSGNEDGLfSIDPSTGEITTAK------PLDReeqssyTLTVTATDGGGPPLSSTATVT 89


                  ....
gi 564330225 2049 VGIQ 2052
Cdd:cd11304    90 ITVL 93
Cadherin pfam00028
Cadherin domain;
145-240 4.06e-12

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 64.63  E-value: 4.06e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   145 QIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGpggapvpELVIAGELDRENRSHYMLQLEAYDG 224
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGGNFRIDPDTG-------DISTTKPLDRESIGEYELTVEATDS 76

                           90
                   ....*....|....*.
gi 564330225   225 GSPPRRAQALLDVTLL 240
Cdd:pfam00028   77 GGPPLSSTATVTITVL 92
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 72-135 5.98e-11

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 60.83  E-value: 5.98e-11
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225     72 YFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAV------TPDGATVEVTVRVADINDHAP 135
Cdd:smart00112   15 YSILSGNDDGL---FSIDPETGEITTTKPLDREEQPEYTLTVEatdgggPPLSSTATVTITVLDVNDNAP 81
Cadherin pfam00028
Cadherin domain;
2811-2916 9.74e-11

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 60.78  E-value: 9.74e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  2811 FHFQVPEGAQRGHSLGHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYLRvdsrapgsgtatsgggGRTRREAP 2888
Cdd:pfam00028    1 YSASVPENAPVGTEVLTVTATDPDLGPNGRIFYSILGGGPGgnFRIDPDTGDISTT----------------KPLDRESI 64

                           90       100
                   ....*....|....*....|....*...
gi 564330225  2889 RELRLEVVARGPLPGSRSATVPVTVDIT 2916
Cdd:pfam00028   65 GEYELTVEATDSGGPPLSSTATVTITVL 92
Cadherin pfam00028
Cadherin domain;
1976-2049 2.23e-10

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 59.62  E-value: 2.23e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225  1976 LATLRAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARspaalgPRDR------VLFIVATDLGRPARSATGVVI 2048
Cdd:pfam00028   15 VLTVTATDPDLGPNGRIFYSILGGGPGGNfRIDPDTGDISTTK------PLDResigeyELTVEATDSGGPPLSSTATVT 88


                   .
gi 564330225  2049 V 2049
Cdd:pfam00028   89 I 89
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1356-1427 4.66e-09

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 55.43  E-value: 4.66e-09
                            10        20        30        40        50        60        70
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 564330225   1356 GVLTYTLVGGaDPEGTFALDSASGRLYLARVLDFESGPAWRaLTVRAEGPGGAGAR-LMRVQVRVQDENEHAP 1427
Cdd:smart00112   11 GKVTYSILSG-NDDGLFSIDPETGEITTTKPLDREEQPEYT-LTVEATDGGGPPLSsTATVTITVLDVNDNAP 81
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 1980-2052 2.72e-07

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 50.43  E-value: 2.72e-07
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   1980 RAEDRDAGANASILYRLAGTPPPGT-TVDSYTGEIRVARSPaalgprDR------VLFIVATDLGRPARSATGVVIVGIQ 2052
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDDGLfSIDPETGEITTTKPL------DReeqpeyTLTVEATDGGGPPLSSTATVTITVL 74
Cadherin pfam00028
Cadherin domain;
44-127 3.13e-07

Cadherin domain;


Pssm-ID: 394985 [Multi-domain]  Cd Length: 92  Bit Score: 50.76  E-value: 3.13e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225    44 QIDEEQPAGTLIGDISAG---LPPGTAPppMYFISAQEGSGVgtdLDIDEHSGVVCTARVLDRERRDRYRFTAV------ 114
Cdd:pfam00028    4 SVPENAPVGTEVLTVTATdpdLGPNGRI--FYSILGGGPGGN---FRIDPDTGDISTTKPLDRESIGEYELTVEatdsgg 78

                           90
                   ....*....|...
gi 564330225   115 TPDGATVEVTVRV 127
Cdd:pfam00028   79 PPLSSTATVTITV 91
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
 1224-1642 7.22e-06

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 52.18  E-value: 7.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1224 VPPGTLVTTLQAKDPDEGENGTILYTLTGSGSELFSLHPHTGELHTA------ASLIRAERPHYVltlsahdqgSPP--- 1294
Cdd:COG3321   797 VGPGPVLTGLVRQCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAgvpvdwSALYPGRGRRRV---------PLPtyp 867

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1295 ---RSASLQLLVQVLPSTRMVESPDLVEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEPASMGVLTYTLVGGADPEGT 1371
Cdd:COG3321   868 fqrEDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAA 947

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1372 FALDSASGRLYLARVLDFESGPAWRALTVRAEGPGGAGARLMRVQVRVQDENEHAPAFARDPLALALPENPEPGATLYTF 1451
Cdd:COG3321   948 AAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAAL 1027

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1452 RASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLIVEATDRPANASRRKATRVSARVFVTD 1531
Cdd:COG3321  1028 LAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALL 1107

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1532 ENDNAPVFASPSRMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGDGHFRLHATTGALSVVRPLDREQRAEHVLT 1611
Cdd:COG3321  1108 LLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAA 1187

                         410       420       430
                  ....*....|....*....|....*....|.
gi 564330225 1612 VVASDHGSPPRSSTQLLTVSVVDVNDEAPAF 1642
Cdd:COG3321  1188 ALAGLAALLLAALLAALLAALLALALAALAA 1218
CA smart00112
Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. ...
 2829-2916 1.81e-05

Cadherin repeats; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. Cadherin domains occur as repeats in the extracellular regions which are thought to mediate cell-cell contact when bound to calcium.


Pssm-ID: 214520 [Multi-domain]  Cd Length: 81  Bit Score: 45.42  E-value: 1.81e-05
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225   2829 QATDEDGGADGLVLYSLATSSP--YFGINQTTGALYL--RVDsrapgsgtatsggggrtrREAPRELRLEVVARGPLPGS 2904
Cdd:smart00112    1 SATDADSGENGKVTYSILSGNDdgLFSIDPETGEITTtkPLD------------------REEQPEYTLTVEATDGGGPP 62

                            90
                    ....*....|..
gi 564330225   2905 RSATVPVTVDIT 2916
Cdd:smart00112   63 LSSTATVTITVL 74
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1609-1948 1.99e-05

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 50.81  E-value: 1.99e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1609 VLTVVASDhgSPPRSSTQLLTVSVVDVNDE--APAFPQQEYNvilrENSppgTSLLTLKATDPDlgaNGQVTYG--GVSG 1684
Cdd:NF038112 1255 TFQLVVSD--GTKTSAPDTVTVLVRNVNRApvAVAGAPATVD----ERS---TVTLDGSGTDAD---GDALTYAwtQTSG 1322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1685 ESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPpllTHITVRVTVEDENdHSPTfGNTHLSLEVPEGqDPQTLTT 1764
Cdd:NF038112 1323 PAVTLTGATTATATFTAPEVTADTQLTFTLTVSDGTAS---ATDTVTVTVRNVN-RAPV-ANAGADQTVDER-STVTLSG 1396

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1765 lRASDPDGGlngQLQYRilgGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQPALSATLLVTVTVLDANDH 1844
Cdd:NF038112 1397 -SATDPDGD---ALTYA---WTQTAGPTVTLTGADTATASFTAPEVAADTELTFQLTVSADGQASADVTVTVTVRNVNRA 1469

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1845 APAFPVPSYSVEvpEDAPVGtllLQLQAHDPDegdnGRVMYYLGAGTAG-AFLLEPTSGELSTATALDREHCASYAFSVT 1923
Cdd:NF038112 1470 PVAHAGESITVD--EGSTVT---LDASATDPD----GDTLTYAWTQVAGpSVTLTGADSAKLTFTAPEVSADTTLTFSLT 1540

                         330       340
                  ....*....|....*....|....*
gi 564330225 1924 AVDGAAAgplSTTVPITVTVRDVND 1948
Cdd:NF038112 1541 VTDGSGS---SGPVVVTVTVKNVNR 1562
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 1850-1949 2.06e-04

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 43.10  E-value: 2.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1850 VPSYSVEVPEDAPvgTLLLQLqAHDPDEgDNGRVMYYLGAGT---AGAFLLEPTSGELSTATALDREHCASYAFSVTAVD 1926
Cdd:cd00031     1 IPDGSAVEGRSRG--SFRVSI-PTDLIA-SSGEIIKISAAGKealPSWLHWEPHSGILEGLEKLDREDKGVHYISVSAAS 76

                          90       100
                  ....*....|....*....|...
gi 564330225 1927 GAAAGPLSTTVpITVTVRDVNDH 1949
Cdd:cd00031    77 LGANVPQTSSV-FSIEVYDENDN 98
myxo_dep_M36 NF038112
myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family ...
 1729-1951 1.37e-03

myxosortase-dependent M36 family metallopeptidase; Members of this bacterial protein family have an M36 family metallopeptidase domain, like fungalysin (see PF02128), and a C-terminal MYXO-CTERM domain (see TIGR03901), suggesting processing and surface-anchoring by the still-unknown putative transpeptidase, myxosortase. Members of this family include MXAN_3564 (mepA), part of the effector cargo of outer membrane vesicles that the species produces in large numbers during predation on other microbes.


Pssm-ID: 468355 [Multi-domain]  Cd Length: 1597  Bit Score: 44.65  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1729 TVRVTVEDENdHSPTfGNTHLSLEVPEGqDPQTLTTlRASDPDGGLNGQLqYRILGGDPsgafaLDLTSGEFGTTRPLDR 1808
Cdd:NF038112 1271 TVTVLVRNVN-RAPV-AVAGAPATVDER-STVTLDG-SGTDADGDALTYA-WTQTSGPA-----VTLTGATTATATFTAP 1340

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 564330225 1809 EVEPAFQL--QIEARDGGQpalSATLLVTVTVLDANDHapafPVPSYSVEVPEDAPvGTLLLQLQAHDPDegdnGRVMYY 1886
Cdd:NF038112 1341 EVTADTQLtfTLTVSDGTA---SATDTVTVTVRNVNRA----PVANAGADQTVDER-STVTLSGSATDPD----GDALTY 1408

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 564330225 1887 LGAGTAG-AFLLEPTSGELSTATALDREHCASYAFSVTAvdgAAAGPLSTTVPITVTVRDVNdHAP 1951
Cdd:NF038112 1409 AWTQTAGpTVTLTGADTATASFTAPEVAADTELTFQLTV---SADGQASADVTVTVTVRNVN-RAP 1470
CA_like cd00031
Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell ...
 2639-2695 2.28e-03

Cadherin repeat-like domain; Cadherins are glycoproteins involved in Ca2+-mediated cell-cell adhesion. The cadherin repeat domains occur as tandem repeats in the extracellular regions, which are thought to mediate cell-cell contact when bound to calcium. They play numerous roles in cell fate, signalling, proliferation, differentiation, and migration; members include E-, N-, P-, T-, VE-, CNR-, proto-, and FAT-family cadherin, desmocollin, and desmoglein, a large variety of domain architectures with varying repeat copy numbers. Cadherin-repeat containing proteins exist as monomers, homodimers, or heterodimers. This family also includes the cadherin-like repeats of extracellular alpha-dystroglycan.


Pssm-ID: 206635  Cd Length: 98  Bit Score: 40.02  E-value: 2.28e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 564330225 2639 PLGLFELDENSGALRLAHPLDCETQAQHQLVVQAADPAGThfalVPVT-----VEVQDVNDH 2695
Cdd:cd00031    41 LPSWLHWEPHSGILEGLEKLDREDKGVHYISVSAASLGAN----VPQTssvfsIEVYDENDN 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH