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Conserved domains on  [gi|530384570|ref|XP_005249716|]
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radial spoke head 10 homolog B isoform X2 [Homo sapiens]

Protein Classification

MORN repeat-containing protein( domain architecture ID 11468649)

membrane-occupation-and-recognition-nexus (MORN) repeat-containing protein may be involved in protein-protein interactions

PubMed:  33296386|35568981

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 1.08e-43

Uncharacterized conserved protein [Function unknown];


:

Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 159.35  E-value: 1.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642   81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642  161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642  213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                        250
                 ....*....|...
gi 530384570 324 FKNGRVYEGAFSN 336
Cdd:COG4642  259 YADGSVYEGEWKN 271
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 1.08e-43

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 159.35  E-value: 1.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642   81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642  161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642  213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                        250
                 ....*....|...
gi 530384570 324 FKNGRVYEGAFSN 336
Cdd:COG4642  259 YADGSVYEGEWKN 271
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 128-335 8.73e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 8.73e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 128 DGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEvvngmrngfgmfkcstqpvsyighWCNGKRHGKGSIYYNQEGTcwYEGD 207
Cdd:PLN03185   7 NGDFYSGSLLGNVPEGPGKYLWSDGCMYEGE------------------------WRRGMRHGNGKISWPSGAT--YEGE 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 208 WVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyPLRNEYIGE 287
Cdd:PLN03185  61 FSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRY-PNGDVFEGSWIQGLQEGPGKYTW----------ANGNVYLGD 129

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530384570 288 FVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFS 335
Cdd:PLN03185 130 MKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWT 177
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 109-129 8.65e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 40.08  E-value: 8.65e-05
                          10        20
                  ....*....|....*....|.
gi 530384570  109 YRGMFSEGLMHGQGTYIWADG 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
225-244 8.73e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 40.02  E-value: 8.73e-05
                           10        20
                   ....*....|....*....|
gi 530384570   225 NIYEGQWEDNMRHGEGRMRW 244
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
 
Name Accession Description Interval E-value
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
86-336 1.08e-43

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 159.35  E-value: 1.08e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:COG4642   81 GGGGKGDGGDGGGGEGGFGGGGGGGGGKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGGIYTFPNGDVYEGEFKNGKPH 160

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 166 GFGMFkcsTQP--VSYIGHWCNGKRHGKGSIYYnqegtcwyegdwvqnikkgwgircyKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:COG4642  161 GQGTL---TYAdgDRYEGEFKNGKRHGQGTLTY-------------------------ANGDVYEGEFKNGQRHGQGTYT 212

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 244 WlttneeytgrwergiQNGFgthtwflkrirssqyplrnEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLT 323
Cdd:COG4642  213 Y---------------ADGD-------------------RYEGEFKNGKRHGQGTLTYADGDRYEGEFKNGKRHGQGTMT 258

                        250
                 ....*....|...
gi 530384570 324 FKNGRVYEGAFSN 336
Cdd:COG4642  259 YADGSVYEGEWKN 271
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
70-341 9.19e-39

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 145.48  E-value: 9.19e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  70 ATQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTW 149
Cdd:COG4642    7 DGAGGGGDATALGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGGEGGVTAAGGGGGGGGGKG 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 150 PDGSMYEGEVVNGMRNGFGmfkcstqpvsyiGHWCNGKRHGKGSIYYNQEGtcWYEGDWVQNIKKGWGIRCYKSGNIYEG 229
Cdd:COG4642   87 DGGDGGGGEGGFGGGGGGG------------GGKKGGGGGGGGVLEGDDGG--GYGGGTADGGRGGGGIYTFPNGDVYEG 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 230 QWEDNMRHGEGRMRWlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyPLRNEYIGEFVNGYRHGRGKFYYASGAMYDG 309
Cdd:COG4642  153 EFKNGKPHGQGTLTY-ADGDRYEGEFKNGKRHGQGTLTY----------ANGDVYEGEFKNGQRHGQGTYTYADGDRYEG 221

                        250       260       270
                 ....*....|....*....|....*....|..
gi 530384570 310 EWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAG 341
Cdd:COG4642  222 EFKNGKRHGQGTLTYADGDRYEGEFKNGKRHG 253
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 128-335 8.73e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 8.73e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 128 DGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEvvngmrngfgmfkcstqpvsyighWCNGKRHGKGSIYYNQEGTcwYEGD 207
Cdd:PLN03185   7 NGDFYSGSLLGNVPEGPGKYLWSDGCMYEGE------------------------WRRGMRHGNGKISWPSGAT--YEGE 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 208 WVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyPLRNEYIGE 287
Cdd:PLN03185  61 FSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRY-PNGDVFEGSWIQGLQEGPGKYTW----------ANGNVYLGD 129

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530384570 288 FVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFS 335
Cdd:PLN03185 130 MKGGKMSGKGTLTWVSGDSYEGQWLDGMMHGFGVYTWSDGGCYVGTWT 177
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 106-320 8.89e-27

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 117.24  E-value: 8.89e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 106 GCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGmfkcstqpvSYIGhwcn 185
Cdd:PLN03185   8 GDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSG---------TYTG---- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 186 gkrhgkgsiyynqEGTCWYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMRWLTTNeEYTGRWERGIQNGFGT 265
Cdd:PLN03185  75 -------------TDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQEGPGKYTWANGN-VYLGDMKGGKMSGKGT 140

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530384570 266 HTWFLKrirssqyplrNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMG 320
Cdd:PLN03185 141 LTWVSG----------DSYEGQWLDGMMHGFGVYTWSDGGCYVGTWTRGLKDGKG 185
COG4642 COG4642
Uncharacterized conserved protein [Function unknown];
133-342 1.10e-25

Uncharacterized conserved protein [Function unknown];


Pssm-ID: 443680 [Multi-domain]  Cd Length: 271  Bit Score: 107.35  E-value: 1.10e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 133 EGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGtcwYEGDWVQNI 212
Cdd:COG4642    1 GGSVAEDGAGGGGDATALGGGGEGGLAAAGGEGGGGLGTLPGGGGYGGGADGGGGGGGGTGVAGGGGG---EGGVTAAGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 213 KKGWGIRCYKSGNIYEGQWEDNMRHGEGRmrwLTTNEEYTGRWERGIQNGFGTHTWFLKRIRSSQ----YPLRNEYIGEF 288
Cdd:COG4642   78 GGGGGGGKGDGGDGGGGEGGFGGGGGGGG---GKKGGGGGGGGVLEGDDGGGYGGGTADGGRGGGgiytFPNGDVYEGEF 154

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 530384570 289 VNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Cdd:COG4642  155 KNGKPHGQGTLTYADGDRYEGEFKNGKRHGQGTLTYANGDVYEGEFKNGQRHGQ 208
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 86-265 4.20e-24

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 108.77  E-value: 4.20e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  86 YEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGMRN 165
Cdd:PLN03185  34 YEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNLKHGLGYQRYPNGDVFEGSWIQGLQE 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 166 GFGMFKCSTQPVsYIGHWCNGKRHGKGSIyynqegtcwyegDWVqnikkgwgircykSGNIYEGQWEDNMRHGEGRMRWl 245
Cdd:PLN03185 114 GPGKYTWANGNV-YLGDMKGGKMSGKGTL------------TWV-------------SGDSYEGQWLDGMMHGFGVYTW- 166

                        170       180
                 ....*....|....*....|
gi 530384570 246 TTNEEYTGRWERGIQNGFGT 265
Cdd:PLN03185 167 SDGGCYVGTWTRGLKDGKGV 186
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 84-300 3.51e-23

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 105.69  E-value: 3.51e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  84 ESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADGLKYEGDFVKNVPMNHGVYTWPDGSMYEGEVVNGM 163
Cdd:PLN03185   9 DFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGSGTYTGTDGTTYKGRWRLNL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 164 RNGFGMfkcstqpvsyighwcngKRHGKGSIyynqegtcwYEGDWVQNIKKGWGIRCYKSGNIYEGQWEDNMRHGEGRMR 243
Cdd:PLN03185  89 KHGLGY-----------------QRYPNGDV---------FEGSWIQGLQEGPGKYTWANGNVYLGDMKGGKMSGKGTLT 142

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 244 WlTTNEEYTGRWERGIQNGFGTHTWflkrirssqyplrNE---YIGEFVNGYRHGRGKFY 300
Cdd:PLN03185 143 W-VSGDSYEGQWLDGMMHGFGVYTW-------------SDggcYVGTWTRGLKDGKGVFY 188
PLN03185 PLN03185
phosphatidylinositol phosphate kinase; Provisional
 279-342 2.41e-08

phosphatidylinositol phosphate kinase; Provisional


Pssm-ID: 215619 [Multi-domain]  Cd Length: 765  Bit Score: 57.92  E-value: 2.41e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530384570 279 PLRNEYIGEFVNGYRHGRGKFYYASGAMYDGEWVSNKKHGMGRLTFKNGRVYEGAFSNDHIAGF 342
Cdd:PLN03185   6 SNGDFYSGSLLGNVPEGPGKYLWSDGCMYEGEWRRGMRHGNGKISWPSGATYEGEFSGGYMHGS 69
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
155-337 2.79e-05

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 45.44  E-value: 2.79e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 155 YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKGSIYYNQEGTCWYEGDWvqniKKGWGIRCYKSGNI-YEGQWED 233
Cdd:COG2849   12 YLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKG----KLGEWKTYYPNGQLkSEGTYKN 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 234 NMRHGEGRMRWlttneeytgrwergiQNGfgthtwflkRIRSsqyplrneyIGEFVNGYRHGRGKFYYASGA-MYDGEWV 312
Cdd:COG2849   88 GKLEGEWKEYY---------------ENG---------KLKS---------EGNYKNGKLHGEWKEYYENGKlKEEGNYK 134

                        170       180
                 ....*....|....*....|....*.
gi 530384570 313 SNKKHGMGRLTFKNGR-VYEGAFSND 337
Cdd:COG2849  135 NGKKDGVWKYYDENGKlVKEEEYKNG 160
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 109-129 8.65e-05

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 40.08  E-value: 8.65e-05
                          10        20
                  ....*....|....*....|.
gi 530384570  109 YRGMFSEGLMHGQGTYIWADG 129
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
225-244 8.73e-05

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 40.02  E-value: 8.73e-05
                           10        20
                   ....*....|....*....|
gi 530384570   225 NIYEGQWEDNMRHGEGRMRW 244
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTY 20
YwqK COG2849
Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];
53-208 2.06e-04

Antitoxin component YwqK of the YwqJK toxin-antitoxin module [Defense mechanisms];


Pssm-ID: 442097 [Multi-domain]  Cd Length: 163  Bit Score: 42.75  E-value: 2.06e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570  53 NEVKPKKDRQNVQQNEDATQYEESILTKLIVESYEGEKVRGLYEGEGFAAFQGGCTYRGMFSEGLMHGQGTYIWADG-LK 131
Cdd:COG2849    1 KKKEGLLKISKYLLSLKLKYELGDTLLEKNGYKSGVKEKTEDSYNEGGKLIKKKLGKGLGKYKKGKLGEWKTYYPNGqLK 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530384570 132 YEGDFVKNVPmnHGVYT--WPDGSM-YEGEVVNGMRNGFGMFKCSTQPVSYIGHWCNGKRHGKgSIYYNQEGTCWYEGDW 208
Cdd:COG2849   81 SEGTYKNGKL--EGEWKeyYENGKLkSEGNYKNGKLHGEWKEYYENGKLKEEGNYKNGKKDGV-WKYYDENGKLVKEEEY 157
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
107-128 2.11e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 38.86  E-value: 2.11e-04
                           10        20
                   ....*....|....*....|..
gi 530384570   107 CTYRGMFSEGLMHGQGTYIWAD 128
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 284-306 2.69e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 38.54  E-value: 2.69e-04
                          10        20
                  ....*....|....*....|...
gi 530384570  284 YIGEFVNGYRHGRGKFYYASGAM 306
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 132-154 7.77e-04

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 37.39  E-value: 7.77e-04
                          10        20
                  ....*....|....*....|...
gi 530384570  132 YEGDFVKNVPMNHGVYTWPDGSM 154
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDGDR 23
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
282-302 8.73e-04

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 37.32  E-value: 8.73e-04
                           10        20
                   ....*....|....*....|.
gi 530384570   282 NEYIGEFVNGYRHGRGKFYYA 302
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYA 21
MORN smart00698
Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;
305-326 1.17e-03

Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases;


Pssm-ID: 197832 [Multi-domain]  Cd Length: 22  Bit Score: 36.93  E-value: 1.17e-03
                           10        20
                   ....*....|....*....|..
gi 530384570   305 AMYDGEWVSNKKHGMGRLTFKN 326
Cdd:smart00698   1 DRYEGEWRNGKRHGRGVYTYAN 22
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 307-327 1.56e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 36.62  E-value: 1.56e-03
                          10        20
                  ....*....|....*....|.
gi 530384570  307 YDGEWVSNKKHGMGRLTFKNG 327
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTWPDG 21
MORN pfam02493
MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple ...
 227-244 3.42e-03

MORN repeat; The MORN (Membrane Occupation and Recognition Nexus) repeat is found in multiple copies in several proteins including junctophilins (See Takeshima et al. Mol. Cell 2000;6:11-22). A MORN-repeat protein has been identified in the parasite Toxoplasma gondiis a dynamic component of cell division apparatus in Toxoplasma gondii. It has been hypothesized to functions as a linker protein between certain membrane regions and the parasite's cytoskeleton.


Pssm-ID: 308220 [Multi-domain]  Cd Length: 23  Bit Score: 35.46  E-value: 3.42e-03
                          10
                  ....*....|....*...
gi 530384570  227 YEGQWEDNMRHGEGRMRW 244
Cdd:pfam02493   1 YEGEWKNGKRHGKGVYTW 18
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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