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Conserved domains on  [gi|528520530|ref|XP_005162968|]
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solute carrier family 12 member 7 isoform X2 [Danio rerio]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
58-1133 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1236.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530    58 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 136
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   137 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 216
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   217 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 296
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   297 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 376
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   377 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 456
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   457 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 515
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   516 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 594
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   595 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 674
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   675 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 754
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   755 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 834
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   835 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 875
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   876 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 955
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   956 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 1035
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  1036 FSERSrrteanasmavrdlfnmkpNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEVMMEGL 1115
Cdd:TIGR00930  875 ITDAE-------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL 935
                         1130
                   ....*....|....*...
gi 528520530  1116 NRVLLVRGGGREVITIYS 1133
Cdd:TIGR00930  936 PPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
58-1133 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1236.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530    58 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 136
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   137 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 216
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   217 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 296
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   297 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 376
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   377 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 456
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   457 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 515
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   516 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 594
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   595 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 674
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   675 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 754
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   755 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 834
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   835 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 875
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   876 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 955
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   956 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 1035
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  1036 FSERSrrteanasmavrdlfnmkpNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEVMMEGL 1115
Cdd:TIGR00930  875 ITDAE-------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL 935
                         1130
                   ....*....|....*...
gi 528520530  1116 NRVLLVRGGGREVITIYS 1133
Cdd:TIGR00930  936 PPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
139-710 3.62e-45

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 170.19  E-value: 3.62e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   139 GVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 218
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   219 LcFYLGTTFAGAMYILGTIEILLTYIVPSAAIFKAEdkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLA 298
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   299 CVVLSILAIYAGVIKTIFeppvfpvcvlgnrtlqnhdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlnsvt 378
Cdd:pfam00324  145 IKIIAIIGFIIVGIILLS-------------------------------------------------------------- 162
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   379 eiqgIPGLTSGVISENMWGKYGPAgmlvekdipsvsasdssqdkympYVVNDI-TAFFTLLVgIYFPSVTGIMAGSNRSG 457
Cdd:pfam00324  163 ----GGNPNDGAIFRYLGDNGGKN-----------------------NFPPGFgKGFISVFV-IAFFAFTGIELVGIAAG 214
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   458 DLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEG---VVLRDKFGDSVKGNLVIGTLSWPS-PWVIVIGSFFSCCGA 533
Cdd:pfam00324  215 EVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpGLLNDSASAASPFVIFFKFLGISGlAPLINAVILTAALSA 294
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   534 GLQSLTGAPRLLQAIARDGIVPFleVFGHGKANGEPTWALLLTALICESGILIASLdaVAPILSMFFLMCYLFVNLACAL 613
Cdd:pfam00324  295 ANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIVWG 370
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   614 QTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALI 693
Cdd:pfam00324  371 LISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFLI 450
                          570
                   ....*....|....*..
gi 528520530   694 RLEEAPPHTKNWRPQML 710
Cdd:pfam00324  451 ILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
147-670 1.13e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.41  E-value: 1.13e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  147 NILGVILFLRMTWIVGTAG--ILEAFIIVSMCCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 223
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  224 GTTFAGAMYILGTIEiLLTYIVPSAAIFkaedkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLACVVLS 303
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  304 ILAIYAGVIktifeppvfpvcvlgnrtlqnhdfdkcmkteiidnVTVTTKLWSLFcsgpelnascneyftlnsvteiqgI 383
Cdd:COG0531   162 LLLFIVVGL-----------------------------------FAFDPANFTPF------------------------L 182
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  384 PGLTSgvisenmwgkygpagmlvekdipsvsasdssqdkympyvvndITAFFTLLVGIyFPSVTGIMAGSNRSGDLRDAQ 463
Cdd:COG0531   183 PAGGG------------------------------------------LSGVLAALALA-FFAFTGFEAIANLAEEAKNPK 219
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  464 RSIPIGTILAIATTTIIYLSCVVLFGacieGVVLRDKFGDSVKGNLVIGTLSWPSP--WVIVIGSFFSCCGAGLQSLTGA 541
Cdd:COG0531   220 RNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGA 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  542 PRLLQAIARDGIVPflEVFGH-GKANGEPTWALLLTALICESGILI--ASLDAVAPILSMFFLMCYLFVNLAcALQTLLR 618
Cdd:COG0531   296 SRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRR 372
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 528520530  619 TPNWRPRFKYYHWALSFLGMSLCLALMFIS---SWYYALVAMLIAGCIYKYIEYR 670
Cdd:COG0531   373 RPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
58-1133 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1236.51  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530    58 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 136
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   137 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 216
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   217 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 296
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   297 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 376
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   377 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 456
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   457 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 515
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   516 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 594
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   595 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 674
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   675 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 754
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   755 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 834
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   835 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 875
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   876 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 955
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   956 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 1035
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  1036 FSERSrrteanasmavrdlfnmkpNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEVMMEGL 1115
Cdd:TIGR00930  875 ITDAE-------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEVLSEDL 935
                         1130
                   ....*....|....*...
gi 528520530  1116 NRVLLVRGGGREVITIYS 1133
Cdd:TIGR00930  936 PPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
139-710 3.62e-45

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 170.19  E-value: 3.62e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   139 GVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 218
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   219 LcFYLGTTFAGAMYILGTIEILLTYIVPSAAIFKAEdkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLA 298
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   299 CVVLSILAIYAGVIKTIFeppvfpvcvlgnrtlqnhdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlnsvt 378
Cdd:pfam00324  145 IKIIAIIGFIIVGIILLS-------------------------------------------------------------- 162
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   379 eiqgIPGLTSGVISENMWGKYGPAgmlvekdipsvsasdssqdkympYVVNDI-TAFFTLLVgIYFPSVTGIMAGSNRSG 457
Cdd:pfam00324  163 ----GGNPNDGAIFRYLGDNGGKN-----------------------NFPPGFgKGFISVFV-IAFFAFTGIELVGIAAG 214
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   458 DLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEG---VVLRDKFGDSVKGNLVIGTLSWPS-PWVIVIGSFFSCCGA 533
Cdd:pfam00324  215 EVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpGLLNDSASAASPFVIFFKFLGISGlAPLINAVILTAALSA 294
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   534 GLQSLTGAPRLLQAIARDGIVPFleVFGHGKANGEPTWALLLTALICESGILIASLdaVAPILSMFFLMCYLFVNLACAL 613
Cdd:pfam00324  295 ANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIVWG 370
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   614 QTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALI 693
Cdd:pfam00324  371 LISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFLI 450
                          570
                   ....*....|....*..
gi 528520530   694 RLEEAPPHTKNWRPQML 710
Cdd:pfam00324  451 ILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
147-670 1.13e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.41  E-value: 1.13e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  147 NILGVILFLRMTWIVGTAG--ILEAFIIVSMCCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 223
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  224 GTTFAGAMYILGTIEiLLTYIVPSAAIFkaedkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLACVVLS 303
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  304 ILAIYAGVIktifeppvfpvcvlgnrtlqnhdfdkcmkteiidnVTVTTKLWSLFcsgpelnascneyftlnsvteiqgI 383
Cdd:COG0531   162 LLLFIVVGL-----------------------------------FAFDPANFTPF------------------------L 182
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  384 PGLTSgvisenmwgkygpagmlvekdipsvsasdssqdkympyvvndITAFFTLLVGIyFPSVTGIMAGSNRSGDLRDAQ 463
Cdd:COG0531   183 PAGGG------------------------------------------LSGVLAALALA-FFAFTGFEAIANLAEEAKNPK 219
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  464 RSIPIGTILAIATTTIIYLSCVVLFGacieGVVLRDKFGDSVKGNLVIGTLSWPSP--WVIVIGSFFSCCGAGLQSLTGA 541
Cdd:COG0531   220 RNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGA 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530  542 PRLLQAIARDGIVPflEVFGH-GKANGEPTWALLLTALICESGILI--ASLDAVAPILSMFFLMCYLFVNLAcALQTLLR 618
Cdd:COG0531   296 SRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRR 372
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 528520530  619 TPNWRPRFKYYHWALSFLGMSLCLALMFIS---SWYYALVAMLIAGCIYKYIEYR 670
Cdd:COG0531   373 RPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
724-896 1.09e-18

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 89.98  E-value: 1.09e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   724 PRLLSFTTQLKAGKGLTIVGSVLEG--TYLSRENQAKRAeqniKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGM 801
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGrlSQKLRSELQKKA----YRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   802 KHNSVLMAWPSNWRQSS-------------------------------------DPHTWRSFIETVRETTAAHLALLVAK 844
Cdd:pfam03522   78 KPNILLMGYKSDWRTCDkeeleeyfnvihdafdlqyavailrlpegldvshllqDQDTEELGLGDETNSSYAEQSSEEQS 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   845 NVDSFPHQERLT------------------------------------------------------------EGTIDVWW 864
Cdd:pfam03522  158 TSNSKQDDDKSKlskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnnitqfqkkqkKGTIDVWW 237
                          250       260       270
                   ....*....|....*....|....*....|..
gi 528520530   865 IVHDGGMLMLLPFLLRQHKVWKKCKMRIFTVA 896
Cdd:pfam03522  238 LYDDGGLTLLLPYILSTRSKWSDCKLRVFALG 269
AA_permease_2 pfam13520
Amino acid permease;
434-659 1.77e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 76.97  E-value: 1.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   434 FFTLLVGIYfpSVTGIMAGSNRSGDLRdaQRSIPIGTILAIATTTIIYL--SCVVLFGACIEGVVLRD-------KFGDS 504
Cdd:pfam13520  191 FAGFLGVLW--SFTGFESAANVSEEVK--KRNVPKAIFIGVIIVGVLYIlvNIAFFGVVPDDEIALSSglgqvaaLLFQA 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   505 VKGNLVIGtlswpspwVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKANGEPTWALLLTALICESGI 584
Cdd:pfam13520  267 VGGKWGAI--------IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILSLILL 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   585 LIASLDAVAPI----LSMFFLMCYLFVNLACALqtLLRTPNWRPRFKYYHWALSFLGMSLCLALMFI-----------SS 649
Cdd:pfam13520  339 LLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGILFSLFLIVAlffppvgpatgSS 416
                          250
                   ....*....|
gi 528520530   650 WYYALVAMLI 659
Cdd:pfam13520  417 LNYAIILIVA 426
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
457-650 3.09e-06

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 51.29  E-value: 3.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   457 GDLRDAQRSIPIGTILAIATTTIIY-LSCVVLFGACIEGVVLRDKFGDSVKGNLVIGTLSWPSPwvIVIGsfFSCCGAGL 535
Cdd:TIGR00911  259 EEVKNPYRTLPIAIIISMPIVTFIYvLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMP--ALVG--LSCFGSVN 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   536 QSLTGAPRLLQAIARDGIVPFLEVFGHGKANgEPTWALLLTaliCESGILIASLDAVAPILSMFFLMCYLFVNLACALQT 615
Cdd:TIGR00911  335 GSLFSSSRLFFVGGREGHLPSLLSMIHVKRL-TPLPSLLIV---CTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLL 410
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 528520530   616 LLR--TPNWRPRFKyYHWALSFLGMSLCLALMFISSW 650
Cdd:TIGR00911  411 WLRykRPEMNRPIK-VPLFFPVFFLLSCLFLIILSLY 446
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
405-613 4.62e-03

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 40.95  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   405 LVEKDIPSVSAS-DSSQDKYMPYVVNDI-----TAFFTLLvgiyfpsvtGIMAGSNRSGDLRDAQRSIPIGTILAIATTT 478
Cdd:TIGR00906  206 FTKADVANWSITeEKGAGGFMPYGFTGVlsgaaTCFFAFI---------GFDAIATTGEEVKNPQRAIPIGIVTSLLVCF 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520530   479 IIYlscvVLFGACIEGVVLRDKFGDSVKGNLVIGTLSW-PSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIV-PF 556
Cdd:TIGR00906  277 VAY----FLMSAALTLMMPYYLLDPDAPFPVAFEYVGWdPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLfKW 352
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 528520530   557 LEVFghGKANGEPTWALLLTALICESGILIASLDAVAPILSMFFLMCYLFVNlACAL 613
Cdd:TIGR00906  353 LAQI--NSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAYSLVA-ACVL 406
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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