NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|444320273|ref|XP_004180793|]
View 

hypothetical protein TBLA_0E02210 [Henningerozyma blattae CBS 6284]

Protein Classification

SKIP/SNW domain-containing protein; molecular chaperone DnaK( domain architecture ID 8095)

SKIP/SNW domain-containing protein similar to human SKIP/SNW1, which may act as a splicing factor and a transcriptional coactivator| molecular chaperone DnaK belongs to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent ""client"" proteins towards degradation

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
SKIP_SNW super family cl03682
SKIP/SNW domain; This domain is found in chromatin proteins.
 119-246 6.48e-41

SKIP/SNW domain; This domain is found in chromatin proteins.


The actual alignment was detected with superfamily member pfam02731:

Pssm-ID: 460666  Cd Length: 152  Bit Score: 142.33  E-value: 6.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 444320273  119 EYKSKNLGSDASEsRNIRIIEHASDPLQPNMIKQKKNQLLQTDEsDIPILHKTGESdrllLSKEEKAAWNIPSAISNWKN 198
Cdd:pfam02731   1 RYTPSQQNSGAKQ-RIIKMVEAQVDPLEPPKFKHKKVPRGPPSP-PPPVLHSPPRK----LTKEEQQEWKIPPCISNWKN 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 444320273  199 PNGFAIDLDKRLVSDKKndpqGIKSLEISSKFEDISNALEEADKKARE 246
Cdd:pfam02731  75 PKGYTIPLDKRLAADGR----GLQDVEINDKFAKLSEALYIAERKARE 118
 
Name Accession Description Interval E-value
SKIP_SNW pfam02731
SKIP/SNW domain; This domain is found in chromatin proteins.
 119-246 6.48e-41

SKIP/SNW domain; This domain is found in chromatin proteins.


Pssm-ID: 460666  Cd Length: 152  Bit Score: 142.33  E-value: 6.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 444320273  119 EYKSKNLGSDASEsRNIRIIEHASDPLQPNMIKQKKNQLLQTDEsDIPILHKTGESdrllLSKEEKAAWNIPSAISNWKN 198
Cdd:pfam02731   1 RYTPSQQNSGAKQ-RIIKMVEAQVDPLEPPKFKHKKVPRGPPSP-PPPVLHSPPRK----LTKEEQQEWKIPPCISNWKN 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 444320273  199 PNGFAIDLDKRLVSDKKndpqGIKSLEISSKFEDISNALEEADKKARE 246
Cdd:pfam02731  75 PKGYTIPLDKRLAADGR----GLQDVEINDKFAKLSEALYIAERKARE 118
 
Name Accession Description Interval E-value
SKIP_SNW pfam02731
SKIP/SNW domain; This domain is found in chromatin proteins.
 119-246 6.48e-41

SKIP/SNW domain; This domain is found in chromatin proteins.


Pssm-ID: 460666  Cd Length: 152  Bit Score: 142.33  E-value: 6.48e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 444320273  119 EYKSKNLGSDASEsRNIRIIEHASDPLQPNMIKQKKNQLLQTDEsDIPILHKTGESdrllLSKEEKAAWNIPSAISNWKN 198
Cdd:pfam02731   1 RYTPSQQNSGAKQ-RIIKMVEAQVDPLEPPKFKHKKVPRGPPSP-PPPVLHSPPRK----LTKEEQQEWKIPPCISNWKN 74

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 444320273  199 PNGFAIDLDKRLVSDKKndpqGIKSLEISSKFEDISNALEEADKKARE 246
Cdd:pfam02731  75 PKGYTIPLDKRLAADGR----GLQDVEINDKFAKLSEALYIAERKARE 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH