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Conserved domains on  [gi|328703944|ref|XP_003242359|]
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transcription initiation factor TFIID subunit 9-like [Acyrthosiphon pisum]

Protein Classification

transcription initiation factor TFIID subunit 9 family protein( domain architecture ID 11130032)

transcription initiation factor TFIID subunit 9 family protein similar to Homo sapiens transcription initiation factor TFIID subunit 9 (TAF9), which is a component of the TFIID basal transcription factor complex that plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription

Gene Ontology:  GO:0006352|GO:0003677|GO:0140297|GO:0005669|GO:0016251|GO:0046982
PubMed:  8598927|16858867

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TFIID-31kDa pfam02291
Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of ...
 7-127 3.23e-53

Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of the 31kD subunit (42kD in drosophila) of transcription initiation factor IID (TAFII31). TAFII31 binds to p53, and is an essential requirement for p53 mediated transcription activation.


:

Pssm-ID: 460525  Cd Length: 122  Bit Score: 166.54  E-value: 3.23e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944    7 NRMPKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFANKEKIDADDVKMAIQMARDGVFLKSPPR 86
Cdd:pfam02291   2 KKRPRDARLIHLILASMGITEYEPRVPLQLLEFAYRYTTDVLEDALVYSEHAGKKQIDVDDVRLAIQSRVNHQFTGPPPR 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 328703944   87 DELIKASNELNKKPLPAIKPASGLRIPQNGSSFLQAKYRLK 127
Cdd:pfam02291  82 EFLLELARERNSKPLPPVKPHYGLRLPPERYCLTAPNYDLK 122
 
Name Accession Description Interval E-value
TFIID-31kDa pfam02291
Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of ...
 7-127 3.23e-53

Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of the 31kD subunit (42kD in drosophila) of transcription initiation factor IID (TAFII31). TAFII31 binds to p53, and is an essential requirement for p53 mediated transcription activation.


Pssm-ID: 460525  Cd Length: 122  Bit Score: 166.54  E-value: 3.23e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944    7 NRMPKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFANKEKIDADDVKMAIQMARDGVFLKSPPR 86
Cdd:pfam02291   2 KKRPRDARLIHLILASMGITEYEPRVPLQLLEFAYRYTTDVLEDALVYSEHAGKKQIDVDDVRLAIQSRVNHQFTGPPPR 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 328703944   87 DELIKASNELNKKPLPAIKPASGLRIPQNGSSFLQAKYRLK 127
Cdd:pfam02291  82 EFLLELARERNSKPLPPVKPHYGLRLPPERYCLTAPNYDLK 122
HFD_TAF9 cd07979
histone-fold domain found in transcription initiation factor TFIID subunit 9 (TAF9) and ...
 10-104 4.23e-32

histone-fold domain found in transcription initiation factor TFIID subunit 9 (TAF9) and similar proteins; The family includes TAF9 (also called TATA Binding Protein (TBP) associated factor 9, RNA polymerase II TBP-associated factor subunit G, STAF31/32, transcription initiation factor TFIID 31 kDa subunit, TAFII-31, TAFII31, transcription initiation factor TFIID 32 kDa subunit, TAFII-32, or TAFII32) and TAF9-like (also called transcription initiation factor TFIID subunit 9B, neuronal cell death-related protein 7, DN-7, or transcription-associated factor TAFII31L), which are essential for cell viability. They are involved in transcriptional activation as well as the repression of distinct but overlapping sets of genes. They may have roles in gene regulation associated with apoptosis. Both TAF9 and TAF9-like are TAFs that are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. TAF9 interacts directly with different transcription factors such as p53, herpes simplex virus activator vp16, and the basal transcription factor TFIIB.


Pssm-ID: 467024  Cd Length: 95  Bit Score: 111.93  E-value: 4.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944  10 PKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFANKEKIDADDVKMAIQMARDGVFLKSPPRDEL 89
Cdd:cd07979    1 PRDAQVIRAILKSMGVTDYEPRVVNQLLEFAYRYTTEVLQDAKVYAEHAGRSQIDEEDVRLAIQSRADHSFTQPPPRELL 80

                         90
                 ....*....|....*
gi 328703944  90 IKASNELNKKPLPAI 104
Cdd:cd07979   81 LELAAEKNSIPLPPI 95
TAF9 COG5094
Transcription initiation factor TFIID, subunit TAF9 (also component of histone ...
 1-135 1.37e-21

Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA) [Transcription];


Pssm-ID: 227425  Cd Length: 145  Bit Score: 86.19  E-value: 1.37e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944   1 MSSSQGN----RMPKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFA---NKEKIDADDVKMAIQ 73
Cdd:COG5094    1 MASGGLNlasvSGPRDVRLIHLILRSLGIEEYEPKVPLQLLEFAHRYTQDVLEDALVYAKHTgrgHIATLGVEDVRLALA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 328703944  74 MARDGVFLKSPPRDELIKASNELNKKPLPAIKPASGLRIPQNGSSFLQAKYRLKTDLNKGRN 135
Cdd:COG5094   81 TKVGRHFVPPPPKEYLLELATERNSKPLPQPDGENGIRLPPEKYCLTNLDWEVLRKDPKKKR 142
 
Name Accession Description Interval E-value
TFIID-31kDa pfam02291
Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of ...
 7-127 3.23e-53

Transcription initiation factor IID, 31kD subunit; This family represents the N-terminus of the 31kD subunit (42kD in drosophila) of transcription initiation factor IID (TAFII31). TAFII31 binds to p53, and is an essential requirement for p53 mediated transcription activation.


Pssm-ID: 460525  Cd Length: 122  Bit Score: 166.54  E-value: 3.23e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944    7 NRMPKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFANKEKIDADDVKMAIQMARDGVFLKSPPR 86
Cdd:pfam02291   2 KKRPRDARLIHLILASMGITEYEPRVPLQLLEFAYRYTTDVLEDALVYSEHAGKKQIDVDDVRLAIQSRVNHQFTGPPPR 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 328703944   87 DELIKASNELNKKPLPAIKPASGLRIPQNGSSFLQAKYRLK 127
Cdd:pfam02291  82 EFLLELARERNSKPLPPVKPHYGLRLPPERYCLTAPNYDLK 122
HFD_TAF9 cd07979
histone-fold domain found in transcription initiation factor TFIID subunit 9 (TAF9) and ...
 10-104 4.23e-32

histone-fold domain found in transcription initiation factor TFIID subunit 9 (TAF9) and similar proteins; The family includes TAF9 (also called TATA Binding Protein (TBP) associated factor 9, RNA polymerase II TBP-associated factor subunit G, STAF31/32, transcription initiation factor TFIID 31 kDa subunit, TAFII-31, TAFII31, transcription initiation factor TFIID 32 kDa subunit, TAFII-32, or TAFII32) and TAF9-like (also called transcription initiation factor TFIID subunit 9B, neuronal cell death-related protein 7, DN-7, or transcription-associated factor TAFII31L), which are essential for cell viability. They are involved in transcriptional activation as well as the repression of distinct but overlapping sets of genes. They may have roles in gene regulation associated with apoptosis. Both TAF9 and TAF9-like are TAFs that are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription. TAF9 interacts directly with different transcription factors such as p53, herpes simplex virus activator vp16, and the basal transcription factor TFIIB.


Pssm-ID: 467024  Cd Length: 95  Bit Score: 111.93  E-value: 4.23e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944  10 PKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFANKEKIDADDVKMAIQMARDGVFLKSPPRDEL 89
Cdd:cd07979    1 PRDAQVIRAILKSMGVTDYEPRVVNQLLEFAYRYTTEVLQDAKVYAEHAGRSQIDEEDVRLAIQSRADHSFTQPPPRELL 80

                         90
                 ....*....|....*
gi 328703944  90 IKASNELNKKPLPAI 104
Cdd:cd07979   81 LELAAEKNSIPLPPI 95
TAF9 COG5094
Transcription initiation factor TFIID, subunit TAF9 (also component of histone ...
 1-135 1.37e-21

Transcription initiation factor TFIID, subunit TAF9 (also component of histone acetyltransferase SAGA) [Transcription];


Pssm-ID: 227425  Cd Length: 145  Bit Score: 86.19  E-value: 1.37e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 328703944   1 MSSSQGN----RMPKDSQTIVSMMNDLGIREYEQQVLNHLLEFNYRYTSLILEEAKACSTFA---NKEKIDADDVKMAIQ 73
Cdd:COG5094    1 MASGGLNlasvSGPRDVRLIHLILRSLGIEEYEPKVPLQLLEFAHRYTQDVLEDALVYAKHTgrgHIATLGVEDVRLALA 80

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 328703944  74 MARDGVFLKSPPRDELIKASNELNKKPLPAIKPASGLRIPQNGSSFLQAKYRLKTDLNKGRN 135
Cdd:COG5094   81 TKVGRHFVPPPPKEYLLELATERNSKPLPQPDGENGIRLPPEKYCLTNLDWEVLRKDPKKKR 142
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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