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Conserved domains on  [gi|2241054966|ref|XP_002532257|]
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protein ALTERED SEED GERMINATION 2 [Ricinus communis]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
48-382 1.89e-27

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 113.47  E-value: 1.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  48 LLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGT--RTIsypSGHFGNIFQTKIMPftDDRKIVTSSADGQVRVGQ 125
Cdd:COG2319   116 LTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKllRTL---TGHSGAVTSVAFSP--DGKLLASGSDDGTVRLWD 190
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 126 VLENGQVDTkkLGKHQGRVYKLAVepgSP--HILYSCGEDGFVQHFDLRSWSATKLFccssfsensRRPSNWIrlNAIVI 203
Cdd:COG2319   191 LATGKLLRT--LTGHTGAVRSVAF---SPdgKLLASGSADGTVRLWDLATGKLLRTL---------TGHSGSV--RSVAF 254
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 204 DPrNPHYFAVGGSDEYARVydirkcrWDASSNSdiavntfcPRHLIGTKNVHITGLAYSSTSELLAS-YNDELIYLFqks 282
Cdd:COG2319   255 SP-DGRLLASGSADGTVRL-------WDLATGE--------LLRTLTGHSGGVNSVAFSPDGKLLASgSDDGTVRLW--- 315
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 283 mgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSfFGPNDEYVLSGSDCGNMFIWKKQGGKLVRLMFSDRQVVNQFD 362
Cdd:COG2319   316 -------------DLATGKLLRTLTGHTGA--VRSVA-FSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVA 379
                         330       340
                  ....*....|....*....|
gi 2241054966 363 PHPHMPMFATCGIEKSVKLW 382
Cdd:COG2319   380 FSPDGRTLASGSADGTVRLW 399
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
48-382 1.89e-27

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 113.47  E-value: 1.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  48 LLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGT--RTIsypSGHFGNIFQTKIMPftDDRKIVTSSADGQVRVGQ 125
Cdd:COG2319   116 LTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKllRTL---TGHSGAVTSVAFSP--DGKLLASGSDDGTVRLWD 190
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 126 VLENGQVDTkkLGKHQGRVYKLAVepgSP--HILYSCGEDGFVQHFDLRSWSATKLFccssfsensRRPSNWIrlNAIVI 203
Cdd:COG2319   191 LATGKLLRT--LTGHTGAVRSVAF---SPdgKLLASGSADGTVRLWDLATGKLLRTL---------TGHSGSV--RSVAF 254
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 204 DPrNPHYFAVGGSDEYARVydirkcrWDASSNSdiavntfcPRHLIGTKNVHITGLAYSSTSELLAS-YNDELIYLFqks 282
Cdd:COG2319   255 SP-DGRLLASGSADGTVRL-------WDLATGE--------LLRTLTGHSGGVNSVAFSPDGKLLASgSDDGTVRLW--- 315
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 283 mgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSfFGPNDEYVLSGSDCGNMFIWKKQGGKLVRLMFSDRQVVNQFD 362
Cdd:COG2319   316 -------------DLATGKLLRTLTGHTGA--VRSVA-FSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVA 379
                         330       340
                  ....*....|....*....|
gi 2241054966 363 PHPHMPMFATCGIEKSVKLW 382
Cdd:COG2319   380 FSPDGRTLASGSADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
44-382 2.99e-27

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 110.50  E-value: 2.99e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  44 LYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGTRTISYpSGHFGNIfqTKIMPFTDDRKIVTSSADGQVRV 123
Cdd:cd00200     1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL-KGHTGPV--RDVAASADGTYLASGSSDKTIRL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 124 gQVLENGQVdTKKLGKHQGRVYKLAVEPgSPHILYSCGEDGfvqhfDLRSWSATKLFCCSSFSENsrrpSNWIrlNAIVI 203
Cdd:cd00200    78 -WDLETGEC-VRTLTGHTSYVSSVAFSP-DGRILSSSSRDK-----TIKVWDVETGKCLTTLRGH----TDWV--NSVAF 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 204 DPrNPHYFAVGGSDEYARVYDIRKCRwdassnsdiavntfcPRHLIGTKNVHITGLAYSST-SELLASYNDELIYLFqks 282
Cdd:cd00200   144 SP-DGTFVASSSQDGTIKLWDLRTGK---------------CVATLTGHTGEVNSVAFSPDgEKLLSSSSDGTIKLW--- 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 283 mgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSfFGPNDEYVLSGSDCGNMFIWKKQGGKLVRLMFSDRQVVNQFD 362
Cdd:cd00200   205 -------------DLSTGKCLGTLRGHENG--VNSVA-FSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLA 268
                         330       340
                  ....*....|....*....|
gi 2241054966 363 PHPHMPMFATCGIEKSVKLW 382
Cdd:cd00200   269 WSPDGKRLASGSADGTIRIW 288
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
36-342 5.06e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 58.56  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  36 EGIVKQISLYK----------KLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDW---VTGTRTISYPSGHFGNIFQTK 102
Cdd:PLN00181  457 EGLCKYLSFSKlrvkadlkqgDLLNSSNLVCAIGFDRDGEFFATAGVNKKIKIFECesiIKDGRDIHYPVVELASRSKLS 536
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 103 IMPFTD--DRKIVTSSADGQVRVGQVLENGQVDTKKlgKHQGRVYKLAVEPGSPHILYSCGEDGFVQHFDLRSWSA---- 176
Cdd:PLN00181  537 GICWNSyiKSQVASSNFEGVVQVWDVARSQLVTEMK--EHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSigti 614
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 177 -TKL-FCCSSFSENSRRPsnwirlnaividprnphyFAVGGSDEYARVYDIRkcrwdassNSDIAVNTFCPRHligtKNV 254
Cdd:PLN00181  615 kTKAnICCVQFPSESGRS------------------LAFGSADHKVYYYDLR--------NPKLPLCTMIGHS----KTV 664
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 255 HITGLAYSSTseLLASYNDELIYLFQKSM---GMGPYPLsissedlqkleepQVYLGHRNSKTVKGVSFfgpNDEYVLSG 331
Cdd:PLN00181  665 SYVRFVDSST--LVSSSTDNTLKLWDLSMsisGINETPL-------------HSFMGHTNVKNFVGLSV---SDGYIATG 726
                         330
                  ....*....|.
gi 2241054966 332 SDCGNMFIWKK 342
Cdd:PLN00181  727 SETNEVFVYHK 737
WD40 pfam00400
WD domain, G-beta repeat;
43-80 3.65e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.57  E-value: 3.65e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2241054966  43 SLYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWD 80
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
43-80 1.35e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.00  E-value: 1.35e-06
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2241054966   43 SLYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWD 80
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
48-382 1.89e-27

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 113.47  E-value: 1.89e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  48 LLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGT--RTIsypSGHFGNIFQTKIMPftDDRKIVTSSADGQVRVGQ 125
Cdd:COG2319   116 LTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKllRTL---TGHSGAVTSVAFSP--DGKLLASGSDDGTVRLWD 190
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 126 VLENGQVDTkkLGKHQGRVYKLAVepgSP--HILYSCGEDGFVQHFDLRSWSATKLFccssfsensRRPSNWIrlNAIVI 203
Cdd:COG2319   191 LATGKLLRT--LTGHTGAVRSVAF---SPdgKLLASGSADGTVRLWDLATGKLLRTL---------TGHSGSV--RSVAF 254
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 204 DPrNPHYFAVGGSDEYARVydirkcrWDASSNSdiavntfcPRHLIGTKNVHITGLAYSSTSELLAS-YNDELIYLFqks 282
Cdd:COG2319   255 SP-DGRLLASGSADGTVRL-------WDLATGE--------LLRTLTGHSGGVNSVAFSPDGKLLASgSDDGTVRLW--- 315
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 283 mgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSfFGPNDEYVLSGSDCGNMFIWKKQGGKLVRLMFSDRQVVNQFD 362
Cdd:COG2319   316 -------------DLATGKLLRTLTGHTGA--VRSVA-FSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVA 379
                         330       340
                  ....*....|....*....|
gi 2241054966 363 PHPHMPMFATCGIEKSVKLW 382
Cdd:COG2319   380 FSPDGRTLASGSADGTVRLW 399
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
44-382 2.99e-27

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 110.50  E-value: 2.99e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  44 LYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGTRTISYpSGHFGNIfqTKIMPFTDDRKIVTSSADGQVRV 123
Cdd:cd00200     1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTL-KGHTGPV--RDVAASADGTYLASGSSDKTIRL 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 124 gQVLENGQVdTKKLGKHQGRVYKLAVEPgSPHILYSCGEDGfvqhfDLRSWSATKLFCCSSFSENsrrpSNWIrlNAIVI 203
Cdd:cd00200    78 -WDLETGEC-VRTLTGHTSYVSSVAFSP-DGRILSSSSRDK-----TIKVWDVETGKCLTTLRGH----TDWV--NSVAF 143
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 204 DPrNPHYFAVGGSDEYARVYDIRKCRwdassnsdiavntfcPRHLIGTKNVHITGLAYSST-SELLASYNDELIYLFqks 282
Cdd:cd00200   144 SP-DGTFVASSSQDGTIKLWDLRTGK---------------CVATLTGHTGEVNSVAFSPDgEKLLSSSSDGTIKLW--- 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 283 mgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSfFGPNDEYVLSGSDCGNMFIWKKQGGKLVRLMFSDRQVVNQFD 362
Cdd:cd00200   205 -------------DLSTGKCLGTLRGHENG--VNSVA-FSPDGYLLASGSEDGTIRVWDLRTGECVQTLSGHTNSVTSLA 268
                         330       340
                  ....*....|....*....|
gi 2241054966 363 PHPHMPMFATCGIEKSVKLW 382
Cdd:cd00200   269 WSPDGKRLASGSADGTIRIW 288
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
32-341 1.86e-20

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 91.24  E-value: 1.86e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  32 YSASE-GIVKQISLY-----KKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGTRTISYpSGHFGNIFQTKIMP 105
Cdd:cd00200    25 ATGSGdGTIKVWDLEtgellRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRTL-TGHTSYVSSVAFSP 103
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 106 ftDDRKIVTSSADGQVRVGQVLENGQVDTkkLGKHQGRVYKLAVEPgSPHILYSCGEDGFVQHFDLRSWSatklfCCSSF 185
Cdd:cd00200   104 --DGRILSSSSRDKTIKVWDVETGKCLTT--LRGHTDWVNSVAFSP-DGTFVASSSQDGTIKLWDLRTGK-----CVATL 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 186 SENsrrpSNWIrlNAIVIDPRNPHyFAVGGSDEYARVYDIRKCRWDASsnsdiavntfCPRHLIGtknvhITGLAYSSTS 265
Cdd:cd00200   174 TGH----TGEV--NSVAFSPDGEK-LLSSSSDGTIKLWDLSTGKCLGT----------LRGHENG-----VNSVAFSPDG 231
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2241054966 266 ELLASYN-DELIYLFqksmgmgpyplsisseDLQKLEEPQVYLGHRNSktVKGVSFFgPNDEYVLSGSDCGNMFIWK 341
Cdd:cd00200   232 YLLASGSeDGTIRVW----------------DLRTGECVQTLSGHTNS--VTSLAWS-PDGKRLASGSADGTIRIWD 289
WD40 COG2319
WD40 repeat [General function prediction only];
44-270 3.04e-19

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 89.59  E-value: 3.04e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  44 LYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVTGTRTISYPsGHFGNIFQTKIMPftDDRKIVTSSADGQVRV 123
Cdd:COG2319   196 LLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLT-GHSGSVRSVAFSP--DGRLLASGSADGTVRL 272
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 124 GQVlENGQVdTKKLGKHQGRVYKLAVepgSP--HILYSCGEDGFVQHFDLRSWSATKLFccssfsensRRPSNWIRlnAI 201
Cdd:COG2319   273 WDL-ATGEL-LRTLTGHSGGVNSVAF---SPdgKLLASGSDDGTVRLWDLATGKLLRTL---------TGHTGAVR--SV 336
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2241054966 202 VIDPrNPHYFAVGGSDEYARVydirkcrWDASSNSdiavntfCPRHLIGTKNVhITGLAYSSTSELLAS 270
Cdd:COG2319   337 AFSP-DGKTLASGSDDGTVRL-------WDLATGE-------LLRTLTGHTGA-VTSVAFSPDGRTLAS 389
PLN00181 PLN00181
protein SPA1-RELATED; Provisional
36-342 5.06e-09

protein SPA1-RELATED; Provisional


Pssm-ID: 177776 [Multi-domain]  Cd Length: 793  Bit Score: 58.56  E-value: 5.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966  36 EGIVKQISLYK----------KLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDW---VTGTRTISYPSGHFGNIFQTK 102
Cdd:PLN00181  457 EGLCKYLSFSKlrvkadlkqgDLLNSSNLVCAIGFDRDGEFFATAGVNKKIKIFECesiIKDGRDIHYPVVELASRSKLS 536
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 103 IMPFTD--DRKIVTSSADGQVRVGQVLENGQVDTKKlgKHQGRVYKLAVEPGSPHILYSCGEDGFVQHFDLRSWSA---- 176
Cdd:PLN00181  537 GICWNSyiKSQVASSNFEGVVQVWDVARSQLVTEMK--EHEKRVWSIDYSSADPTLLASGSDDGSVKLWSINQGVSigti 614
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 177 -TKL-FCCSSFSENSRRPsnwirlnaividprnphyFAVGGSDEYARVYDIRkcrwdassNSDIAVNTFCPRHligtKNV 254
Cdd:PLN00181  615 kTKAnICCVQFPSESGRS------------------LAFGSADHKVYYYDLR--------NPKLPLCTMIGHS----KTV 664
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2241054966 255 HITGLAYSSTseLLASYNDELIYLFQKSM---GMGPYPLsissedlqkleepQVYLGHRNSKTVKGVSFfgpNDEYVLSG 331
Cdd:PLN00181  665 SYVRFVDSST--LVSSSTDNTLKLWDLSMsisGINETPL-------------HSFMGHTNVKNFVGLSV---SDGYIATG 726
                         330
                  ....*....|.
gi 2241054966 332 SDCGNMFIWKK 342
Cdd:PLN00181  727 SETNEVFVYHK 737
WD40 pfam00400
WD domain, G-beta repeat;
43-80 3.65e-07

WD domain, G-beta repeat;


Pssm-ID: 459801 [Multi-domain]  Cd Length: 39  Bit Score: 46.57  E-value: 3.65e-07
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2241054966  43 SLYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWD 80
Cdd:pfam00400   2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
43-80 1.35e-06

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 45.00  E-value: 1.35e-06
                           10        20        30
                   ....*....|....*....|....*....|....*...
gi 2241054966   43 SLYKKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWD 80
Cdd:smart00320   3 ELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
WD40 COG2319
WD40 repeat [General function prediction only];
46-83 5.88e-05

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 45.29  E-value: 5.88e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 2241054966  46 KKLLGHEGCVNSVEFNYTGDLLVSGSDDKQVMFWDWVT 83
Cdd:COG2319   366 RTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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