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Conserved domains on  [gi|2396491875|ref|XP_002308317|]
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3-hydroxyisobutyryl-CoA hydrolase-like protein 3, mitochondrial isoform X1 [Populus trichocarpa]

Protein Classification

enoyl-CoA hydratase/isomerase family protein( domain architecture ID 11240944)

enoyl-CoA hydratase/isomerase family protein plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate; similar to Homo sapiens 3-hydroxyisobutyryl-CoA hydrolase and Cereibacter sphaeroides Enoyl-CoA hydratase

CATH:  3.90.226.10
EC:  3.1.2.-
Gene Ontology:  GO:0016790
PubMed:  18470480|11263873
SCOP:  4004188

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 3.99e-149

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


:

Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 424.57  E-value: 3.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVvAEIRKDKNTPVVQKVFTAEYS 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRAL-YEAAKAGGGEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  99 LICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLALTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 179 IStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNdpHQDINALLAEYG-HDPESESQLKSLLPRIISTFGPNkSVEEI 257
Cdd:pfam16113 158 LN-GADALAAGLATHYVPSARLPALEEALAALDWSD--PADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 258 IEKLKshqlsADPKVVEWANDALQGIGKGAPFSLCLTQKYFSRVAFAfgkisnelsTLSGVMKTEYRIALRSSLRNDFAE 337
Cdd:pfam16113 234 IAALE-----AEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL---------SLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2396491875 338 GVRAVLVDKDQKPKWNPSSLEEVDQSEIESLF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 3.99e-149

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 424.57  E-value: 3.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVvAEIRKDKNTPVVQKVFTAEYS 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRAL-YEAAKAGGGEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  99 LICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLALTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 179 IStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNdpHQDINALLAEYG-HDPESESQLKSLLPRIISTFGPNkSVEEI 257
Cdd:pfam16113 158 LN-GADALAAGLATHYVPSARLPALEEALAALDWSD--PADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 258 IEKLKshqlsADPKVVEWANDALQGIGKGAPFSLCLTQKYFSRVAFAfgkisnelsTLSGVMKTEYRIALRSSLRNDFAE 337
Cdd:pfam16113 234 IAALE-----AEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL---------SLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2396491875 338 GVRAVLVDKDQKPKWNPSSLEEVDQSEIESLF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 17-371 1.32e-122

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 357.59  E-value: 1.32e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDM--DIKYKtfMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVvAEIRKDKNTPVVQKVFT 94
Cdd:PRK05617   11 GGVGVITLNRPKALNALSLEMirAIDAA--LDAWEDDDAVAAVVIEGAGERGFCAGGDIRAL-YEAARAGDPLAADRFFR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLAL 174
Cdd:PRK05617   88 EEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGA--LGTYLAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 175 TGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDPhQDINALLAEYGHDPEsESQLKSLLPRIISTFGPNkSV 254
Cdd:PRK05617  166 TGARIS-AADALYAGLADHFVPSADLPALLDALISLRWDSGA-DVVDAALAAFATPAP-ASELAAQRAWIDECFAGD-TV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 255 EEIIEKLKSHQlsadpkvVEWANDALQGIGKGAPFSLCLTQKYFSRvafafgkisNELSTLSGVMKTEYRIALRSSLRND 334
Cdd:PRK05617  242 EDIIAALEADG-------GEFAAKTADTLRSRSPTSLKVTLEQLRR---------ARGLTLEECLRRELRLALAMLRSPD 305

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 2396491875 335 FAEGVRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKP 371
Cdd:PRK05617  306 FVEGVRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 15-209 1.19e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 155.03  E-value: 1.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  15 HPNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSsPRAFCAGMDIKGVVAEIRKDkntPVVQKVFT 94
Cdd:cd06558     5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAG---EEARAFIR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGeGSVGNYLAL 174
Cdd:cd06558    81 ELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVG-PARARELLL 159

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2396491875 175 TGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQ 209
Cdd:cd06558   160 TGRRIS-AEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-209 2.22e-39

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 140.69  E-value: 2.22e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSsPRAFCAGMDIKgvvaEIRKDKNTPVVQKVFTAE 96
Cdd:COG1024     7 GGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLK----ELAAAADPEEARAFARGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGsVGNYLALTG 176
Cdd:COG1024    82 QRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLA-RAKELLLTG 160

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2396491875 177 KRIStPSDALFVGLGSHYVPSGNLVQLKEALLQ 209
Cdd:COG1024   161 RRID-AEEALELGLVNRVVPDDELLAAALALAA 192
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-179 1.26e-13

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 72.18  E-value: 1.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKA-LNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVVAEIRKDKNTPV---VQKV 92
Cdd:TIGR02441  21 GDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLsqeGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  93 FTaeyslicKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTE--RTVLAMPENGIGLFPDVGFSyiaAKSPGEGSVGN 170
Cdd:TIGR02441 101 FE-------RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGT---QRLPKLTGVPA 170

                         170
                  ....*....|.
gi 2396491875 171 YL--ALTGKRI 179
Cdd:TIGR02441 171 ALdmMLTGKKI 181
 
Name Accession Description Interval E-value
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 19-369 3.99e-149

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 424.57  E-value: 3.99e-149
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVvAEIRKDKNTPVVQKVFTAEYS 98
Cdd:pfam16113   1 VGVITLNRPKALNALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRAL-YEAAKAGGGEAGRDFFREEYR 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  99 LICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLALTGKR 178
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTERTRFAMPETAIGLFPDVGGSYFLSRLPGE--LGLYLALTGAR 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 179 IStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNdpHQDINALLAEYG-HDPESESQLKSLLPRIISTFGPNkSVEEI 257
Cdd:pfam16113 158 LN-GADALAAGLATHYVPSARLPALEEALAALDWSD--PADVDAVLAEFAeESDPPPSPLAAHREAIDRCFSAD-TVEEI 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 258 IEKLKshqlsADPKVVEWANDALQGIGKGAPFSLCLTQKYFSRVAFAfgkisnelsTLSGVMKTEYRIALRSSLRNDFAE 337
Cdd:pfam16113 234 IAALE-----AEADGDEWAAETLKTLRKRSPTSLKVTLRQLRRGRKL---------SLAECLRMEYRLALRCLRRPDFVE 299

                         330       340       350
                  ....*....|....*....|....*....|..
gi 2396491875 338 GVRAVLVDKDQKPKWNPSSLEEVDQSEIESLF 369
Cdd:pfam16113 300 GVRALLIDKDRNPKWSPATLEEVTDEMVDAYF 331
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 17-371 1.32e-122

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 357.59  E-value: 1.32e-122
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDM--DIKYKtfMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVvAEIRKDKNTPVVQKVFT 94
Cdd:PRK05617   11 GGVGVITLNRPKALNALSLEMirAIDAA--LDAWEDDDAVAAVVIEGAGERGFCAGGDIRAL-YEAARAGDPLAADRFFR 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLAL 174
Cdd:PRK05617   88 EEYRLNALIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRAPGA--LGTYLAL 165

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 175 TGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDPhQDINALLAEYGHDPEsESQLKSLLPRIISTFGPNkSV 254
Cdd:PRK05617  166 TGARIS-AADALYAGLADHFVPSADLPALLDALISLRWDSGA-DVVDAALAAFATPAP-ASELAAQRAWIDECFAGD-TV 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 255 EEIIEKLKSHQlsadpkvVEWANDALQGIGKGAPFSLCLTQKYFSRvafafgkisNELSTLSGVMKTEYRIALRSSLRND 334
Cdd:PRK05617  242 EDIIAALEADG-------GEFAAKTADTLRSRSPTSLKVTLEQLRR---------ARGLTLEECLRRELRLALAMLRSPD 305

                         330       340       350
                  ....*....|....*....|....*....|....*..
gi 2396491875 335 FAEGVRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKP 371
Cdd:PRK05617  306 FVEGVRAVLIDKDRNPKWSPATLEDVTPEDVEAFFAP 342
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
 18-378 1.34e-70

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 225.83  E-value: 1.34e-70
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKgVVAEIRKDKN--TPVVQKVfta 95
Cdd:PLN02874   20 RVRVITLNRPRQLNVISLSVVSLLAEFLEQWEKDDSVELIIIKGAG-RAFSAGGDLK-MFYDGRESDDscLEVVYRM--- 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  96 eYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLALT 175
Cdd:PLN02874   95 -YWLCYHIHTYKKTQVALVHGLVMGGGAGLMVPMKFRVVTEKTVFATPEASVGFHTDCGFSYILSRLPGH--LGEYLALT 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 176 GKRISTpSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDphQDINALLAEYGHDPE-SESQLKSLLPRIISTFGPNkSV 254
Cdd:PLN02874  172 GARLNG-KEMVACGLATHFVPSEKLPELEKRLLNLNSGDE--SAVQEAIEEFSKDVQaDEDSILNKQSWINECFSKD-TV 247

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 255 EEIIEKLKShQLSADPKvvEWANDALQGIGKGAPFSLCLTQKYFSrvafafgkiSNELSTLSGVMKTEYRI---ALRSSL 331
Cdd:PLN02874  248 EEIIKAFES-EASKTGN--EWIKETLKGLRRSSPTGLKITLRSIR---------EGRKQSLAECLKKEFRLtmnILRSTV 315

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 2396491875 332 RNDFAEGVRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKPLSPEAEL 378
Cdd:PLN02874  316 SDDVYEGIRALVIDKDNAPKWNPSTLDEVTDEKVDLVFQPFKAREEL 362
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
 24-378 4.56e-63

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 207.14  E-value: 4.56e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  24 LDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVvAEIRKDKNTPVVQKVFTAEYSLICKI 103
Cdd:PLN02851   57 LNRPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSG-RAFCSGADVVSL-YHLINEGNVEECKLFFENLYKFVYLQ 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 104 SEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPgeGSVGNYLALTGKRISTpS 183
Cdd:PLN02851  135 GTYLKPNVAIMDGITMGCGAGISIPGMFRVVTDKTVFAHPEVQMGFHPDAGASYYLSRLP--GYLGEYLALTGQKLNG-V 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 184 DALFVGLGSHYVPSGNLVQLKEALLQItFSNDPHQdINALLAEYGH--DPESESQLKSLlpRIISTFGPNKSVEEIIEKL 261
Cdd:PLN02851  212 EMIACGLATHYCLNARLPLIEERLGKL-LTDDPAV-IEDSLAQYGDlvYPDKSSVLHKI--ETIDKCFGHDTVEEIIEAL 287

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 262 KSHQLSAdpkVVEWANDALQGIGKGAPFSLCLTQKYFSRVAFafgkisnelSTLSGVMKTEYRIAL---RSSLRNDFAEG 338
Cdd:PLN02851  288 ENEAASS---YDEWCKKALKKIKEASPLSLKVTLQSIREGRF---------QTLDQCLAREYRISLcgvSKWVSGDFCEG 355

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|...
gi 2396491875 339 VRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKPLS---PEAEL 378
Cdd:PLN02851  356 VRARLVDKDFAPKWDPPSLGEVSKDMVDCYFTPLDeseSELEL 398
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
 17-377 5.17e-63

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 206.49  E-value: 5.17e-63
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDkNTPVVQKVFTAE 96
Cdd:PLN02988   17 SSVRILTLNRPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHG-RAFCAGGDVAAVVRDIEQG-NWRLGANFFSDE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPgeGSVGNYLALTG 176
Cdd:PLN02988   95 YMLNYVMATYSKAQVSILNGIVMGGGAGVSVHGRFRIATENTVFAMPETALGLFPDVGASYFLSRLP--GFFGEYVGLTG 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 177 KRISTpSDALFVGLGSHYVPSGNLVQLKEALLQITfSNDPhQDINALLAEYGHDPESESQLKSLLPRIISTFGPNKSVEE 256
Cdd:PLN02988  173 ARLDG-AEMLACGLATHFVPSTRLTALEADLCRIG-SNDP-TFASTILDAYTQHPRLKPQSAYHRLDVIDRCFSRRTVEE 249

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 257 IIEKLKSHqlsADPKVVEWANDALQGIGKGAPFSLCLTQKYFSRvafafgkisNELSTLSGVMKTEYRI---ALRSSLRN 333
Cdd:PLN02988  250 IISALERE---ATQEADGWISATIQALKKASPASLKISLRSIRE---------GRLQGVGQCLIREYRMvchVMKGEISK 317

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....
gi 2396491875 334 DFAEGVRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKPLSPEAE 377
Cdd:PLN02988  318 DFVEGCRAILVDKDKNPKWEPRRLEDMKDSMVEQYFERVEEEEE 361
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
 24-374 2.23e-56

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 189.51  E-value: 2.23e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  24 LDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVaEIRKDKNTPVVQKVFTAEYSLICKI 103
Cdd:PLN02157   52 LNRPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSG-RAFCAGGDIVSLY-HLRKRGSPDAIREFFSSLYSFIYLL 129

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 104 SEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgsVGNYLALTGKRISTpS 183
Cdd:PLN02157  130 GTYLKPHVAILNGVTMGGGTGVSIPGTFRVATDRTIFATPETIIGFHPDAGASFNLSHLPGR--LGEYLGLTGLKLSG-A 206

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 184 DALFVGLGSHYVPSGNLVQLKEALLQItFSNDPHQDINAL--LAEYGHdPESESQLK--SLLPRIIStfgpNKSVEEIIE 259
Cdd:PLN02157  207 EMLACGLATHYIRSEEIPVMEEQLKKL-LTDDPSVVESCLekCAEVAH-PEKTGVIRriDLLEKCFS----HDTVEEIID 280

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875 260 KLkshQLSADPKVVEWANDALQGIGKGAPFSLCLTQKYFSRvafafgkisNELSTLSGVMKTEYRIALR---SSLRNDFA 336
Cdd:PLN02157  281 SL---EIEAGRRKDTWCITTLRRLKESSPLSLKVALRSIRE---------GRLQTLDQCLIREYRMSLQgliGPMSGNFC 348

                         330       340       350
                  ....*....|....*....|....*....|....*...
gi 2396491875 337 EGVRAVLVDKDQKPKWNPSSLEEVDQSEIESLFKPLSP 374
Cdd:PLN02157  349 EGVRARLIDKDEAPKWDPPSLEKVSEDMVDDYFCALTP 386
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 15-209 1.19e-45

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 155.03  E-value: 1.19e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  15 HPNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSsPRAFCAGMDIKGVVAEIRKDkntPVVQKVFT 94
Cdd:cd06558     5 RDGGVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAG---EEARAFIR 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGeGSVGNYLAL 174
Cdd:cd06558    81 ELQELLRALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVG-PARARELLL 159

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2396491875 175 TGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQ 209
Cdd:cd06558   160 TGRRIS-AEEALELGLVDEVVPDEELLAAALELAR 193
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 17-209 2.22e-39

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 140.69  E-value: 2.22e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSsPRAFCAGMDIKgvvaEIRKDKNTPVVQKVFTAE 96
Cdd:COG1024     7 GGVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLK----ELAAAADPEEARAFARGL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGsVGNYLALTG 176
Cdd:COG1024    82 QRLFRALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLA-RAKELLLTG 160

                         170       180       190
                  ....*....|....*....|....*....|...
gi 2396491875 177 KRIStPSDALFVGLGSHYVPSGNLVQLKEALLQ 209
Cdd:COG1024   161 RRID-AEEALELGLVNRVVPDDELLAAALALAA 192
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 17-200 9.15e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 98.79  E-value: 9.15e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMdikYKTF---MDEWESDPRVRCVLVEGSsPRAFCAGMDIKGVVAeiRKDKNTPVVQKVF 93
Cdd:PRK06688   13 DGVLTITINRPDKKNALTAAM---YQALadaLEAAATDPAVRVVVLTGA-GRAFSAGGDIKDFPK--APPKPPDELAPVN 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  94 TAeyslICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgSVGNYLA 173
Cdd:PRK06688   87 RF----LRAIAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGR-ARAAEML 161

                         170       180
                  ....*....|....*....|....*..
gi 2396491875 174 LTGKRISTPsDALFVGLGSHYVPSGNL 200
Cdd:PRK06688  162 LLGEPLSAE-EALRIGLVNRVVPAAEL 187
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 18-161 1.33e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 95.62  E-value: 1.33e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDkntpvVQKVFtaeY 97
Cdd:PRK06072    9 GYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEG-RAFCVGADLSEFAPDFAID-----LRETF---Y 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2396491875  98 SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAK 161
Cdd:PRK06072   80 PIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLK 143
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 8-216 9.06e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 93.26  E-value: 9.06e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875   8 EFVKGNIHPNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKgvvaEIRKDKNTP 87
Cdd:PRK07657    3 QNISVDYVTPHVVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLK----ERAGMNEEQ 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  88 VVQKVftaeySLICK-ISEYKK---PYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSP 163
Cdd:PRK07657   79 VRHAV-----SLIRTtMEMVEQlpqPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLI 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2396491875 164 GEGSVGNyLALTGKRISTpSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK07657  154 GVGRAKE-LIYTGRRISA-QEAKEIGLVEFVVPAHLLEEKAIEIAEKIASNGP 204
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 16-196 9.54e-21

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 90.50  E-value: 9.54e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  16 PNGVAVLTLDRPKALNAMNLdmdikykTFMDE-------WESDPRVRCVLVEGsSPRAFCAGMDIKGVVAEIRKDKNTPv 88
Cdd:pfam00378   3 NAGVAVITLNRPEAVNALSA-------ELITEliqalekLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALY- 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  89 vQKVFtaeYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgSV 168
Cdd:pfam00378  74 -RENV---LDLWTLLYTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGH-SK 148

                         170       180
                  ....*....|....*....|....*...
gi 2396491875 169 GNYLALTGKRIStPSDALFVGLGSHYVP 196
Cdd:pfam00378 149 AMEMLLLGRRIS-AQEALKWGLVDKVVP 175
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
18-216 5.88e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 88.28  E-value: 5.88e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVVAEIRKDKNTPVVQKVFTAEy 97
Cdd:PRK05980   12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEFSASVAAGADVALRDFVRRGQ- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSvGNYLALTGK 177
Cdd:PRK05980   91 AMTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKR-ALELLLTGD 169

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2396491875 178 RIStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK05980  170 AFS-AERALEIGLVNAVVPHEELLPAARALARRIIRHSP 207
PLN02600 PLN02600
enoyl-CoA hydratase
 17-198 9.09e-18

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 81.77  E-value: 9.09e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKgvvaeIRKDKNTPVVQKVFTAE 96
Cdd:PLN02600    3 SGIVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLK-----ERRKMSPSEVQKFVNSL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgSVGNYLALTG 176
Cdd:PLN02600   78 RSTFSSLEALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGR-SRAKELIFTG 156

                         170       180
                  ....*....|....*....|..
gi 2396491875 177 KRISTpSDALFVGLGSHYVPSG 198
Cdd:PLN02600  157 RRIGA-REAASMGLVNYCVPAG 177
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
18-216 1.63e-15

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 75.55  E-value: 1.63e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIkgvvAEIrKDKNTPVVQKVFTAEY 97
Cdd:PRK05809   13 HIAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADI----SEM-KDLNEEEGRKFGLLGN 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGsVGNYLALTGK 177
Cdd:PRK05809   88 KVFRKLENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPG-KAKELIYTGD 166

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 2396491875 178 RISTpSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK05809  167 MINA-EEALRIGLVNKVVEPEKLMEEAKALANKIAANAP 204
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 14-200 5.09e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 74.36  E-value: 5.09e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  14 IHPNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVA----EIRKDKNTPVV 89
Cdd:PRK06210   11 VADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAG-RGFCAGADMGELQTidpsDGRRDTDVRPF 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  90 QK----VFTAEYSLICKIseyKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGE 165
Cdd:PRK06210   90 VGnrrpDYQTRYHFLTAL---RKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGH 166

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2396491875 166 GSVGNYLaLTGKRISTpSDALFVGLGSHYVPSGNL 200
Cdd:PRK06210  167 ANALDLL-LSARTFYA-EEALRLGLVNRVVPPDEL 199
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 18-227 5.75e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 73.85  E-value: 5.75e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKgvvaEIRKDKNTPVVQkvfTAEY 97
Cdd:PRK06190   13 RVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAGLDLK----ELGGDGSAYGAQ---DALP 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 SLICKISEYKKPYVSLMDG--VTMGFGIGLsgHGRYRIVTERTVLAMPENGIGLFPDVGFSyiaAKSPgeGSVGNYLA-- 173
Cdd:PRK06190   85 NPSPAWPAMRKPVIGAINGaaVTGGLELAL--ACDILIASERARFADTHARVGILPGWGLS---VRLP--QKVGIGRArr 157

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2396491875 174 --LTGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDPhQDINALLAEY 227
Cdd:PRK06190  158 msLTGDFLD-AADALRAGLVTEVVPHDELLPRARRLAASIAGNNP-AAVRALKASY 211
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 18-216 6.80e-15

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 73.92  E-value: 6.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVVAeiRKDKNTPvvQKVF---T 94
Cdd:PRK06494   13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAA--GGKRGWP--ESGFgglT 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLickiseyKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSY-IAAKSPGEGSVGnyLA 173
Cdd:PRK06494   89 SRFDL-------DKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHrLPRQIGLKRAMG--MI 159

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2396491875 174 LTGKRISTPsDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK06494  160 LTGRRVTAR-EGLELGFVNEVVPAGELLAAAERWADDILACSP 201
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 18-216 7.41e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 70.89  E-value: 7.41e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGvVAEIRKDKN-TPVVQKVFTAE 96
Cdd:PRK06127   20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQ-FEESRSDAEaVAAYEQAVEAA 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLickISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLfpdvGFSYIAAKS------PgegSVGN 170
Cdd:PRK06127   99 QAA---LADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGL----GYGYDGVKNlvdlvgP---SAAK 168

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2396491875 171 YLALTGKRIsTPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK06127  169 DLFYTARRF-DAAEALRIGLVHRVTAADDLETALADYAATIAGNAP 213
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 17-179 1.26e-13

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 72.18  E-value: 1.26e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKA-LNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVVAEIRKDKNTPV---VQKV 92
Cdd:TIGR02441  21 GDVAVVKIDSPNSkVNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLsqeGQEM 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  93 FTaeyslicKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTE--RTVLAMPENGIGLFPDVGFSyiaAKSPGEGSVGN 170
Cdd:TIGR02441 101 FE-------RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKdrKTLLGLPEVMLGLLPGAGGT---QRLPKLTGVPA 170

                         170
                  ....*....|.
gi 2396491875 171 YL--ALTGKRI 179
Cdd:TIGR02441 171 ALdmMLTGKKI 181
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 17-207 4.33e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 68.54  E-value: 4.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKgvvaEIRKDKNTPVVQKvfTAE 96
Cdd:PRK08138   16 DGVALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGE-KVFAAGADIK----EFATAGAIEMYLR--HTE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YsLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKspgegSVGNY----L 172
Cdd:PRK08138   89 R-YWEAIAQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVR-----AVGKFkamrM 162

                         170       180       190
                  ....*....|....*....|....*....|....*
gi 2396491875 173 ALTGKRISTPsDALFVGLGSHYVPSGNLvqLKEAL 207
Cdd:PRK08138  163 ALTGCMVPAP-EALAIGLVSEVVEDEQT--LPRAL 194
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 17-200 6.28e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 68.04  E-value: 6.28e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKgvvaEIRKDKNTPVVQKVFTAE 96
Cdd:PRK08139   19 DGVATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLK----EMRAARGLAYFRALFARC 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLF---PDVGFSY-IAAKSPGEgsvgnyL 172
Cdd:PRK08139   94 SRVMQAIVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVALSRnVPRKQAME------M 167

                         170       180
                  ....*....|....*....|....*...
gi 2396491875 173 ALTGKRISTpSDALFVGLGSHYVPSGNL 200
Cdd:PRK08139  168 LLTGEFIDA-ATAREWGLVNRVVPADAL 194
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 17-165 1.25e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 67.37  E-value: 1.25e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEW-ESDPRVrcVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPV---VQKV 92
Cdd:PRK07659   14 GRVATIMLNRPEALNALDEPMLKELLQALKEVaESSAHI--VVLRGNG-RGFSAGGDIKMMLSSNDESKFDGVmntISEI 90

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2396491875  93 FTAEYSLickiseyKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGE 165
Cdd:PRK07659   91 VVTLYTM-------PKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGE 156
PLN02888 PLN02888
enoyl-CoA hydratase
 16-125 1.42e-11

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 64.39  E-value: 1.42e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  16 PNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDI-------KGVVaeirKDKNT-P 87
Cdd:PLN02888   17 RNGIATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSG-RAFCSGVDLtaaeevfKGDV----KDVETdP 91

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2396491875  88 VVQkvftaeyslickISEYKKPYVSLMDG--VTMGFGIGL 125
Cdd:PLN02888   92 VAQ------------MERCRKPIIGAINGfaITAGFEIAL 119
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
18-200 2.80e-11

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 63.21  E-value: 2.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDP-RVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPVVQKVFTAE 96
Cdd:PRK05981   13 GVAILTLDHPEVMNAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAG-RGFCTGANLQGRGSGGRESDSGGDAGAALETA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YS-LICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSVGNyLALT 175
Cdd:PRK05981   92 YHpFLRRLRNLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAME-LSLL 170

                         170       180
                  ....*....|....*....|....*.
gi 2396491875 176 GKRIstPSD-ALFVGLGSHYVPSGNL 200
Cdd:PRK05981  171 GEKL--PAEtALQWGLVNRVVDDAEL 194
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 18-207 8.75e-11

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 61.57  E-value: 8.75e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKAlNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPVV---QKVFT 94
Cdd:PRK07658   11 HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGEG-RFFSAGADIKEFTSVTEAEQATELAqlgQVTFE 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 aeyslicKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPdvGFSyiaakspgeGS------V 168
Cdd:PRK07658   89 -------RVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIP--GFA---------GTqrlpryV 150

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 2396491875 169 GNYLA----LTGKRIsTPSDALFVGLGSHYVPSGNLvqLKEAL 207
Cdd:PRK07658  151 GKAKAlemmLTSEPI-TGAEALKWGLVNGVFPEETL--LDDAK 190
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 18-217 2.74e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 60.32  E-value: 2.74e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKGVVAEIRKDKNTPVVQKVFTAEy 97
Cdd:PRK05995   13 QVATVTLNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGK-AFCAGADLNWMKKMAGYSDDENRADARRLAD- 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 sLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSvgNYLALTGK 177
Cdd:PRK05995   91 -MLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIPATISPYVIRAMGERAA--RRYFLTAE 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 2396491875 178 RIsTPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDPH 217
Cdd:PRK05995  168 RF-DAAEALRLGLVHEVVPAEALDAKVDELLAALVANSPQ 206
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 18-197 3.82e-10

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 59.78  E-value: 3.82e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDI-----KGVVAEIrkdkNTPVVQkv 92
Cdd:PRK09674   11 RVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNA-RFFAAGADLnemaeKDLAATL----NDPRPQ-- 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  93 ftaeysLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgSVGNYL 172
Cdd:PRK09674   84 ------LWQRLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGK-SLASQM 156

                         170       180
                  ....*....|....*....|....*
gi 2396491875 173 ALTGKRIsTPSDALFVGLGSHYVPS 197
Cdd:PRK09674  157 VLTGESI-TAQQAQQAGLVSEVFPP 180
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 15-201 4.27e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 59.85  E-value: 4.27e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  15 HPN-GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIK--GVVAEIrkDKNTPVVQK 91
Cdd:PRK05864   15 HPRpEIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAG-RGFSSGADHKsaGVVPHV--EGLTRPTYA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  92 VFTAEY--SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVL--AMPENGIGLfPDVGFSYIAAKSPGEgS 167
Cdd:PRK05864   92 LRSMELldDVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraAGINNGLTA-SELGLSYLLPRAIGS-S 169

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2396491875 168 VGNYLALTGKRIsTPSDALFVGLGSHYVPSGNLV 201
Cdd:PRK05864  170 RAFEIMLTGRDV-DAEEAERIGLVSRQVPDEQLL 202
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 17-241 4.59e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 59.66  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKGVVAEirkdknTPVVQKVFTAE 96
Cdd:PRK06143   15 RGVATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATL------DQASAEAFISR 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICK-ISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLfPDVGFSYIAAKSPGEGSVgNYLALT 175
Cdd:PRK06143   89 LRDLCDaVRHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVGI-PSVIHAALLPRLIGWART-RWLLLT 166

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2396491875 176 GKRISTPSdALFVGLGSHYVPSGNLVQLKEALLqitfsndphqdinALLAEYGhdPESESQLKSLL 241
Cdd:PRK06143  167 GETIDAAQ-ALAWGLVDRVVPLAELDAAVERLA-------------ASLAGCG--PQALRQQKRLL 216
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 17-143 5.45e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 59.62  E-value: 5.45e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIK----------GVVAEIRKDknt 86
Cdd:PRK06144   16 GGIARITFNRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAqfrafstaedAVAYERRID--- 92

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2396491875  87 pvvqKVFTAeyslickISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMP 143
Cdd:PRK06144   93 ----RVLGA-------LEQLRVPTIAAIAGACVGGGAAIAAACDLRIATPSARFGFP 138
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 17-75 5.62e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 59.63  E-value: 5.62e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKG 75
Cdd:PRK08260   12 DGIATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVIVTGAG-RAFCAGADLSA 69
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
18-149 7.49e-10

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 58.94  E-value: 7.49e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPkALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTP----VVQKVF 93
Cdd:PRK06495   13 HVAVVTLDNP-PVNALSRELRDELIAVFDEISERPDVRVVVLTGAG-KVFCAGADLKGRPDVIKGPGDLRahnrRTRECF 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2396491875  94 TAeyslickISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGL 149
Cdd:PRK06495   91 HA-------IRECAKPVIAAVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGL 139
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 19-207 7.76e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 58.90  E-value: 7.76e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGsSPRAFCAGMDIKGVVAEIRKDkntpvvqkVFTAEY- 97
Cdd:PRK05862   14 VGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITG-SEKAFAAGADIKEMADLSFMD--------VYKGDYi 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSVGNyLALTGk 177
Cdd:PRK05862   85 TNWEKVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMD-LCLTG- 162

                         170       180       190
                  ....*....|....*....|....*....|
gi 2396491875 178 RISTPSDALFVGLGSHYVPSGNLvqLKEAL 207
Cdd:PRK05862  163 RMMDAAEAERAGLVSRVVPADKL--LDEAL 190
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 16-216 1.47e-09

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 58.28  E-value: 1.47e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  16 PNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPVVQKVFTA 95
Cdd:PRK05674   13 PRGFATLWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRG-RHFSAGADLAWMQQSADLDYNTNLDDARELA 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  96 EysLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVgFSYIAAKSPGEGSVGNYlALT 175
Cdd:PRK05674   92 E--LMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAV-ISPFVVKAIGERAARRY-ALT 167

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 2396491875 176 GKRISTpSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK05674  168 AERFDG-RRARELGLLAESYPAAELEAQVEAWIANLLLNSP 207
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
21-207 1.49e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 58.19  E-value: 1.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  21 VLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKGVVA-----EIRKDKNTPVVQKVFTA 95
Cdd:PRK07799   17 IVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGG-AFCAGMDLKAATKkppgdSFKDGSYDPSRIDALLK 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  96 EYSLickiseyKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPdVGFSYIAAKSPGEGSVGNYLALT 175
Cdd:PRK07799   96 GRRL-------TKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFP-MGGSAVRLVRQIPYTVACDLLLT 167

                         170       180       190
                  ....*....|....*....|....*....|..
gi 2396491875 176 GKRISTPsDALFVGLGSHYVPSGNlvQLKEAL 207
Cdd:PRK07799  168 GRHITAA-EAKEIGLIGHVVPDGQ--ALDKAL 196
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
17-193 1.68e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 57.97  E-value: 1.68e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAE-----------IRKDKN 85
Cdd:PRK07509   11 DGIADVRLNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGEG-GAFCAGLDVKSVASSpgnavkllfkrLPGNAN 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  86 TPvvQKVFTAEYSLICkiseykkPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGfSYIAAKSPGE 165
Cdd:PRK07509   90 LA--QRVSLGWRRLPV-------PVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMA-GTVSLRGLVR 159

                         170       180
                  ....*....|....*....|....*...
gi 2396491875 166 GSVGNYLALTGkRISTPSDALFVGLGSH 193
Cdd:PRK07509  160 KDVARELTYTA-RVFSAEEALELGLVTH 186
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
18-78 7.17e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 56.15  E-value: 7.17e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVA 78
Cdd:PRK08252   12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAG-GTFCAGMDLKAFAR 71
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 15-190 7.43e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 55.89  E-value: 7.43e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  15 HPNGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGsSPRAFCAGMDIKGVVAEIRKDKNtPVVQKVft 94
Cdd:PRK05870    9 VDDGVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTG-AGKAFCAGADLTALGAAPGRPAE-DGLRRI-- 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 aeYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGeGSVGNYLAL 174
Cdd:PRK05870   85 --YDGFLAVASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVG-PQVARAALL 161

                         170
                  ....*....|....*.
gi 2396491875 175 TGKRISTPSdALFVGL 190
Cdd:PRK05870  162 FGMRFDAEA-AVRHGL 176
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 19-198 9.74e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 55.70  E-value: 9.74e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  19 VAVLTLDRPKAlNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKgVVAEIRKDkNTPVVQKVFTAEYS 98
Cdd:PRK09076   13 VAILTLNNPPA-NTWTADSLQALKQLVLELNADKDVYALVITGDGEKFFSAGADLN-LFADGDKA-VAREMARRFGEAFE 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  99 licKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSvGNYLALTGKR 178
Cdd:PRK09076   90 ---ALSAFRGVSIAAINGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGW-AKRMILCGER 165

                         170       180
                  ....*....|....*....|
gi 2396491875 179 ISTPSdALFVGLGSHYVPSG 198
Cdd:PRK09076  166 VDAAT-ALRIGLVEEVVEKG 184
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 16-192 1.22e-08

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 55.68  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  16 PN-GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRaFCAGMDIKgVVAEIRKD-------KNTP 87
Cdd:PLN02664   14 PNsSVFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDH-FCSGIDLK-TLNSISEQsssgdrgRSGE 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  88 VVQKVFTAEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGfsyIAAKSPGEGS 167
Cdd:PLN02664   92 RLRRKIKFLQDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLG---TLQRLPSIVG 168

                         170       180
                  ....*....|....*....|....*..
gi 2396491875 168 VGNY--LALTGKRISTpSDALFVGLGS 192
Cdd:PLN02664  169 YGNAmeLALTGRRFSG-SEAKELGLVS 194
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
18-206 1.30e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 55.45  E-value: 1.30e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPVVQKVFTAEy 97
Cdd:PRK07468   14 GVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAG-KSFCAGGDLGWMRAQMTADRATRIEEARRLAM- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  98 sLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSpGEGSvGNYLALTGK 177
Cdd:PRK07468   92 -MLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVARM-GEAN-ARRVFMSAR 168

                         170       180
                  ....*....|....*....|....*....
gi 2396491875 178 RISTpSDALFVGLGSHYVPSGNLVQLKEA 206
Cdd:PRK07468  169 LFDA-EEAVRLGLLSRVVPAERLDAAVEA 196
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 17-210 5.83e-08

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 53.47  E-value: 5.83e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRcVLVEGSSPRAFCAGMDIKGVVAEIrKDKNTPVVQKVFTAE 96
Cdd:PRK09120   16 DGIAWVTLNRPEKRNAMSPTLNREMIDVLDALEFDDDAG-VLVLTGAGDAWSAGMDLKEYFRET-DAQPEILQERIRREA 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKspgegSVGN----YL 172
Cdd:PRK09120   94 YGWWRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMAD-----TVGHrdalYY 168

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 2396491875 173 ALTGKRIsTPSDALFVGLGSHYVPsgnLVQLKEALLQI 210
Cdd:PRK09120  169 IMTGETF-TGRKAAEMGLVNESVP---LAQLRARTREL 202
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 18-72 6.74e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 52.99  E-value: 6.74e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWEsDPRVRCVLVEGSSpRAFCAGMD 72
Cdd:PRK08140   13 GVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAG-RGFCAGQD 65
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
18-75 6.90e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 53.51  E-value: 6.90e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKG 75
Cdd:PRK08272   19 RIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAG-KGFCAGYDLSA 75
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
18-153 8.16e-08

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 52.76  E-value: 8.16e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVlVEGSSPRAFCAGMDIKGVVAEIRKDKNTPVVQkvfTAEY 97
Cdd:PRK07827   15 GVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAV-VLTHTGGTFCAGADLSEAGGGGGDPYDAAVAR---AREM 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2396491875  98 -SLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDV 153
Cdd:PRK07827   91 tALLRAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAI 147
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 18-180 9.92e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 52.69  E-value: 9.92e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDkntPVVQkvftAE- 96
Cdd:PRK07511   12 STLVLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGAG-GFFCAGGNLNRLLENRAKP---PSVQ----AAs 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 ----YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKS-PGEgsVGNY 171
Cdd:PRK07511   84 idglHDWIRAIRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARAlPRQ--LATE 161


                  ....*....
gi 2396491875 172 LALTGKRIS 180
Cdd:PRK07511  162 LLLEGKPIS 170
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
18-218 1.65e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 51.90  E-value: 1.65e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAM--NLDMDiKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKGVVAEIRKDKNTPV------- 88
Cdd:PRK09245   12 HIVTLTMNRPETRNALsdNDAVD-ALVAACAAINADRSVRAVILTGAGT-AFSSGGNVKDMRARVGAFGGSPAdirqgyr 89

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  89 --VQKVFTAEYSLickiseyKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEg 166
Cdd:PRK09245   90 hgIQRIPLALYNL-------EVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGM- 161

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2396491875 167 SVGNYLALTGKRISTPSdALFVGLGSHYVPSGNLVQLKEALLQITFSNDPHQ 218
Cdd:PRK09245  162 ARAAEMAFTGDAIDAAT-ALEWGLVSRVVPADQLLPAARALAERIAANPPHA 212
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
17-198 4.86e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 50.40  E-value: 4.86e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDprVRCVLVEGSSPRaFCAGMDIkgvvAEIRKDKNTPVVQKVFT-- 94
Cdd:PRK08150   10 GGVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDL----SELRERDAGEGMHHSRRwh 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLI--CKIseykkPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEGSVGNyL 172
Cdd:PRK08150   83 RVFDKIqyGRV-----PVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTD-M 156

                         170       180
                  ....*....|....*....|....*.
gi 2396491875 173 ALTGkRISTPSDALFVGLGSHYVPSG 198
Cdd:PRK08150  157 MLTG-RVYDAQEGERLGLAQYLVPAG 181
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
15-164 8.97e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 49.79  E-value: 8.97e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  15 HPnGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSsPRAFCAGMDIKGVVAEIRKDKNtpVVQKVFT 94
Cdd:PRK06023   13 HP-GVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLGT-EGCFSAGNDMQDFLAAAMGGTS--FGSEILD 88

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  95 AEYSLickiSEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPG 164
Cdd:PRK06023   89 FLIAL----AEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMG 154
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
17-216 1.93e-06

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 48.92  E-value: 1.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKAlNAMNL----DMDIKYKTFMDewesDPRVRCVLVEGSSPRAFCAGMDIKGVVAEIRKDKNTPVvqkv 92
Cdd:PRK03580   11 GSILEITLDRPKA-NAIDAktsfAMGEVFLNFRD----DPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGP---- 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  93 ftAEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVG-FSYIAAKSPgeGSVGNY 171
Cdd:PRK03580   82 --GGFAGLTEIFDLDKPVIAAVNGYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGgVLRLPKRLP--PAIANE 157

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 2396491875 172 LALTGKRIStPSDALFVGLGSHYVPSGNLVQLKEALLQITFSNDP 216
Cdd:PRK03580  158 MVMTGRRMD-AEEALRWGIVNRVVPQAELMDRARELAQQLVNSAP 201
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
13-144 2.87e-06

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 48.04  E-value: 2.87e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  13 NIHPNGVAVLTLDRPKaLNAMNLDMDIKYKTFMDEWESDPRVRCVLV--EGsspRAFCAGMDIKgvvaEIrkdKNTPVVQ 90
Cdd:PRK07938    6 TTPEPGIAEVTVDYPP-VNALPSAGWFALADAITAAGADPDTRVVVLraEG---RGFNAGVDIK----EL---QATPGFT 74

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2396491875  91 KVFTAE---YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPE 144
Cdd:PRK07938   75 ALIDANrgcFAAFRAVYECAVPVIAAVHGFCLGGGIGLVGNADVIVASDDATFGLPE 131
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 17-180 3.51e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 47.81  E-value: 3.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPrAFCAGMDIKGVVAEIRKDkNTPVVQKVftAE 96
Cdd:PRK07260   10 DDLATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDED-DVQSLVKI--AE 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 ysLICKIS----EYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKSPGEgSVGNYL 172
Cdd:PRK07260   86 --LVNEISfaikQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFIQAFVGVGLAPDAGGLFLLTRAIGL-NRATHL 162


                  ....*...
gi 2396491875 173 ALTGKRIS 180
Cdd:PRK07260  163 AMTGEALT 170
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
13-154 4.52e-06

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 48.74  E-value: 4.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  13 NIHPNGVAVLTLDRP-KALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSPRAFCAGMDIKgvvaeirkdkntpVVQK 91
Cdd:PRK11154   10 NVREDNIAVITIDVPgEKMNTLKAEFAEQVRAILKQLREDKELKGVVFISGKPDNFIAGADIN-------------MLAA 76

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2396491875  92 VFTAE---------YSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVT--ERTVLAMPENGIGLFPDVG 154
Cdd:PRK11154   77 CKTAQeaealarqgQQLFAEIEALPIPVVAAIHGACLGGGLELALACHYRVCTddPKTVLGLPEVQLGLLPGSG 150
PRK12478 PRK12478
crotonase/enoyl-CoA hydratase family protein;
19-75 8.75e-05

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 183548  Cd Length: 298  Bit Score: 43.79  E-value: 8.75e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVRCVLVEGSSpRAFCAGMDIKG 75
Cdd:PRK12478   15 VATITLNRPEQLNTIVPPMPDEIEAAIGLAERDQDIKVIVLRGAG-RAFSGGYDFGG 70
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
18-190 2.77e-04

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 41.98  E-value: 2.77e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  18 GVAVLTLDRPKALNAMNLDMDIKYKTFMDEWESDPRVrcVLVEGsSPRAFCAGMDIKGVVAEIRKDKNTPvvqkvFTAE- 96
Cdd:PRK07112   13 DVCFLQLHRPEAQNTINDRLIAECMDVLDRCEHAATI--VVLEG-LPEVFCFGADFSAIAEKPDAGRADL-----IDAEp 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  97 -YSLICKISEykKPYVSL--MDG-VTMGfGIGLSGHGRYRIVTERTVLAMPENGIGLFPDVGFSYIAAKspgegsVG--- 169
Cdd:PRK07112   85 lYDLWHRLAT--GPYVTIahVRGkVNAG-GIGFVAASDIVIADETAPFSLSELLFGLIPACVLPFLIRR------IGtqk 155

                         170       180
                  ....*....|....*....|..
gi 2396491875 170 -NYLALTGKRISTpSDALFVGL 190
Cdd:PRK07112  156 aHYMTLMTQPVTA-QQAFSWGL 176
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 19-77 3.36e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 41.93  E-value: 3.36e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2396491875  19 VAVLTLDRPKALNAMNLDMDIKYKTFMDEwESDPRVRCVLVEGSSPrAFCAGMDIKGVV 77
Cdd:PRK07854   10 VLTIELQRPERRNALNAELCEELREAVRK-AVDESARAIVLTGQGT-VFCAGADLSGDV 66
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
17-156 3.36e-04

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 41.88  E-value: 3.36e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2396491875  17 NGVAVLTLDRPKALNAMNLDmdiKYKTFMD-----EWESDprVRCVLVEGSSpRAFCAGMDIKGVVAEIRKDKNTPVVQk 91
Cdd:PRK08258   25 DGVATITLNRPERKNPLTFE---SYAELRDlfrelVYADD--VKAVVLTGAG-GNFCSGGDVHEIIGPLTKMDMPELLA- 97

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2396491875  92 vFT-AEYSLICKISEYKKPYVSLMDGVTMGFGIGLSGHGRYRIVTERTVLAMpengigLFPDVGFS 156
Cdd:PRK08258   98 -FTrMTGDLVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAF------LFTRVGLA 156
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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