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Conserved domains on  [gi|157864056|ref|XP_001687575|]
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putative NADH-ubiquinone oxidoreductase,mitochondrial [Leishmania major strain Friedlin]

Protein Classification

PTZ00304 family protein( domain architecture ID 11488363)

PTZ00304 family protein

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PTZ00304 PTZ00304
NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional
1-459 0e+00

NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional


:

Pssm-ID: 185547 [Multi-domain]  Cd Length: 461  Bit Score: 966.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   1 MRQGWLRSSAALLERVHGHLKDQDRIFTNLYNDFGTGIDAAERRGDWYRTKDILLKGHDWVINEIKASGLRGRGGAGFPS 80
Cdd:PTZ00304   3 RAQGFLRLTASLLVRVHGGLKDQDRIFTNLYRDFDTYIDGALKRGDWYRTKDILLKGHDWIIDEIKKSGLRGRGGAGFPS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  81 GLKWSFMPKKKQDDRPSYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIH 160
Cdd:PTZ00304  83 GLKWSFMPKVKPDGRPSYLVVNADESEPGTCKDREIMRHDPHKLVEGALLAGFAMRARAAYIYIRGEFYNEARALQQAID 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 161 EAYEKGYLGKNACGSGWDFDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTI 240
Cdd:PTZ00304 163 EAYKKGFLGKNACGSGYDFDVYVHRGAGAYICGEETALIESIEGKPGKPRLKPPFPANVGLYGCPTTVTNVETVAVSPTI 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 241 IRRGPQWFAQFGRKGNAGTKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWDNLLCVIPGGSSCPLIPKHICDD 320
Cdd:PTZ00304 243 LRRGPQWFASFGRPNNAGTKLFCISGHVNNPCTVEEEMSIPLRELIERHCGGVRGGWDNLLCVIPGGSSVPLIPKEICDN 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 321 ILMDYDALKEAQTGLGTAAVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWD 400
Cdd:PTZ00304 323 VLMDFDALKEVQSGLGTAAVIVMDKSTDIIDAILRLSKFYKHESCGQCTPCREGTPWLVKMMERFVVGNADKEEIDTLEE 402
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157864056 401 VSKQMEGRSICALGTAAAWPVQGLIRHFKPLMEERIERFWEANPHWGQPGSPWRRWKTH 459
Cdd:PTZ00304 403 VSKQIEGHTICALGDAAAWPVQGLIRHFRPEIEERIERYWEANPHWGKSGSPWRRWKTH 461
 
Name Accession Description Interval E-value
PTZ00304 PTZ00304
NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional
1-459 0e+00

NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional


Pssm-ID: 185547 [Multi-domain]  Cd Length: 461  Bit Score: 966.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   1 MRQGWLRSSAALLERVHGHLKDQDRIFTNLYNDFGTGIDAAERRGDWYRTKDILLKGHDWVINEIKASGLRGRGGAGFPS 80
Cdd:PTZ00304   3 RAQGFLRLTASLLVRVHGGLKDQDRIFTNLYRDFDTYIDGALKRGDWYRTKDILLKGHDWIIDEIKKSGLRGRGGAGFPS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  81 GLKWSFMPKKKQDDRPSYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIH 160
Cdd:PTZ00304  83 GLKWSFMPKVKPDGRPSYLVVNADESEPGTCKDREIMRHDPHKLVEGALLAGFAMRARAAYIYIRGEFYNEARALQQAID 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 161 EAYEKGYLGKNACGSGWDFDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTI 240
Cdd:PTZ00304 163 EAYKKGFLGKNACGSGYDFDVYVHRGAGAYICGEETALIESIEGKPGKPRLKPPFPANVGLYGCPTTVTNVETVAVSPTI 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 241 IRRGPQWFAQFGRKGNAGTKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWDNLLCVIPGGSSCPLIPKHICDD 320
Cdd:PTZ00304 243 LRRGPQWFASFGRPNNAGTKLFCISGHVNNPCTVEEEMSIPLRELIERHCGGVRGGWDNLLCVIPGGSSVPLIPKEICDN 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 321 ILMDYDALKEAQTGLGTAAVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWD 400
Cdd:PTZ00304 323 VLMDFDALKEVQSGLGTAAVIVMDKSTDIIDAILRLSKFYKHESCGQCTPCREGTPWLVKMMERFVVGNADKEEIDTLEE 402
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157864056 401 VSKQMEGRSICALGTAAAWPVQGLIRHFKPLMEERIERFWEANPHWGQPGSPWRRWKTH 459
Cdd:PTZ00304 403 VSKQIEGHTICALGDAAAWPVQGLIRHFRPEIEERIERYWEANPHWGKSGSPWRRWKTH 461
nuoF_fam TIGR01959
NADH-quinone oxidoreductase, F subunit; This model describes the F chain of complexes that ...
25-436 0e+00

NADH-quinone oxidoreductase, F subunit; This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport]


Pssm-ID: 131014  Cd Length: 411  Bit Score: 651.71  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   25 RIFTNLYNDFGTGIDAAERRGDWYRTKDILLK-GHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKKkQDDRPSYIVVNC 103
Cdd:TIGR01959   1 VLTTNLDNPESWTLEEYEKRGGYDALRKALEEmSPDDIIEEVKDSGLRGRGGAGFPTGLKWSFMPKD-DSPKPKYLVCNA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  104 DESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWDFDLYT 183
Cdd:TIGR01959  80 DESEPGTCKDRDLMEFDPHQLIEGMIIAAYAIGAHRGYIYIRGEFIKEAENLEAAIAEAYAAGLLGKNILGSGFDFELFV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  184 YRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKGNAGTKLFC 263
Cdd:TIGR01959 160 HRGAGAYICGEETALLESLEGKRGQPRLKPPFPAVFGLYGKPTVINNVETLASVPAILRRGADWYRKLGKEKSPGTKLFS 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  264 ISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWdNLLCVIPGGSSCPLIPKHICDDILMDYDALKEAQTGLGTAAVIVM 343
Cdd:TIGR01959 240 VSGHVNKPGNYELPLGTPLRELLEDYAGGMRGGW-KLKAVIPGGSSTPVLPAEQHLDAPMDYDSLAAAGSMLGTGAVIVM 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  344 DKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAAWPVQG 423
Cdd:TIGR01959 319 DESTCMVKAVRRLSEFYAHESCGQCTPCREGTGWMVKILERIEEGEGTKEDIDLLLSVCKQIEGKTICALGDAAAWPVQS 398
                         410
                  ....*....|...
gi 157864056  424 LIRHFKPLMEERI 436
Cdd:TIGR01959 399 AIKHFRDEFEAHI 411
NuoF COG1894
NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) [Energy production and ...
21-437 0e+00

NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) [Energy production and conversion]; NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 441498 [Multi-domain]  Cd Length: 418  Bit Score: 651.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  21 KDQDRI-FTNLYNDFGTGIDAAERRGDWYRTKDILLK-GHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKkkQDDRPSY 98
Cdd:COG1894    1 KKQTRVlLRNCGIIDPESLEDYIARGGYQALRKALTEmTPEEVIEEVKDSGLRGRGGAGFPTGLKWSFVPK--APGDPKY 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  99 IVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWD 178
Cdd:COG1894   79 LVCNADEGEPGTFKDRSLLEGDPHQLIEGMIIAAYAIGATKGYIYIRGEYPLAIERLEKAIEEAREAGLLGKNILGSGFD 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 179 FDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKGNAG 258
Cdd:COG1894  159 FDIEVHRGAGAYICGEETALLESLEGKRGQPRLKPPFPAVSGLWGKPTVVNNVETLANVPHIIRNGAEWFASIGTEKSKG 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 259 TKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGwDNLLCVIPGGSSCPLIPKHiCDDILMDYDALKEAQTGLGTA 338
Cdd:COG1894  239 TKLFSLSGHVKNPGLYEVPMGTTLRELIYDIGGGIRGG-RKLKAVQPGGPSGGCLPAE-HLDTPMDYESLAAAGSMLGSG 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 339 AVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAA 418
Cdd:COG1894  317 GMIVMDETTCMVDVARFFLEFYAHESCGKCTPCREGTGWMLEILDRIEAGEGTEEDLDLLEDLADTIKGTSLCALGDAAP 396
                        410
                 ....*....|....*....
gi 157864056 419 WPVQGLIRHFKPLMEERIE 437
Cdd:COG1894  397 NPVLSTLKYFRDEFEAHIK 415
Complex1_51K pfam01512
Respiratory-chain NADH dehydrogenase 51 Kd subunit;
65-235 2.45e-56

Respiratory-chain NADH dehydrogenase 51 Kd subunit;


Pssm-ID: 460237 [Multi-domain]  Cd Length: 150  Bit Score: 184.25  E-value: 2.45e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   65 IKASGLRGRGGAGFPSGLKWSFMPKKKQDdrpsYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYI 144
Cdd:pfam01512   1 VKEAGIVGRGGAGFPTHVKLSPPPKKKIK----YLIVNGAECEPGLTKDRRLMRERPHEIIEGIKIAAYALGAKRGVIGI 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  145 RGEFYNEWRSVEKAIHEAYEKGylgknacgsgwdFDLYTYRGAGAYICGEETAMIASIEGGqGKPRLKPpfPANVGLygc 224
Cdd:pfam01512  77 RDEKPEAIAALEKAIAEARAAG------------FDIEVHRGAGAYPCGEEKALIYSLTGR-GVPRGKP--PADVGV--- 138
                         170
                  ....*....|.
gi 157864056  225 ptTVTNCETVA 235
Cdd:pfam01512 139 --VVNNVETLA 147
NADH_4Fe-4S smart00928
NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;
350-395 1.78e-18

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;


Pssm-ID: 197996 [Multi-domain]  Cd Length: 46  Bit Score: 78.72  E-value: 1.78e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 157864056   350 INAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEI 395
Cdd:smart00928   1 VDAARRLMEFYAHESCGKCTPCREGTGWLLEILDRIEEGEGTEEDL 46
 
Name Accession Description Interval E-value
PTZ00304 PTZ00304
NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional
1-459 0e+00

NADH dehydrogenase [ubiquinone] flavoprotein 1; Provisional


Pssm-ID: 185547 [Multi-domain]  Cd Length: 461  Bit Score: 966.56  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   1 MRQGWLRSSAALLERVHGHLKDQDRIFTNLYNDFGTGIDAAERRGDWYRTKDILLKGHDWVINEIKASGLRGRGGAGFPS 80
Cdd:PTZ00304   3 RAQGFLRLTASLLVRVHGGLKDQDRIFTNLYRDFDTYIDGALKRGDWYRTKDILLKGHDWIIDEIKKSGLRGRGGAGFPS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  81 GLKWSFMPKKKQDDRPSYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIH 160
Cdd:PTZ00304  83 GLKWSFMPKVKPDGRPSYLVVNADESEPGTCKDREIMRHDPHKLVEGALLAGFAMRARAAYIYIRGEFYNEARALQQAID 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 161 EAYEKGYLGKNACGSGWDFDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTI 240
Cdd:PTZ00304 163 EAYKKGFLGKNACGSGYDFDVYVHRGAGAYICGEETALIESIEGKPGKPRLKPPFPANVGLYGCPTTVTNVETVAVSPTI 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 241 IRRGPQWFAQFGRKGNAGTKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWDNLLCVIPGGSSCPLIPKHICDD 320
Cdd:PTZ00304 243 LRRGPQWFASFGRPNNAGTKLFCISGHVNNPCTVEEEMSIPLRELIERHCGGVRGGWDNLLCVIPGGSSVPLIPKEICDN 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 321 ILMDYDALKEAQTGLGTAAVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWD 400
Cdd:PTZ00304 323 VLMDFDALKEVQSGLGTAAVIVMDKSTDIIDAILRLSKFYKHESCGQCTPCREGTPWLVKMMERFVVGNADKEEIDTLEE 402
                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 157864056 401 VSKQMEGRSICALGTAAAWPVQGLIRHFKPLMEERIERFWEANPHWGQPGSPWRRWKTH 459
Cdd:PTZ00304 403 VSKQIEGHTICALGDAAAWPVQGLIRHFRPEIEERIERYWEANPHWGKSGSPWRRWKTH 461
PRK13596 PRK13596
NADH-quinone oxidoreductase subunit NuoF;
20-439 0e+00

NADH-quinone oxidoreductase subunit NuoF;


Pssm-ID: 237441  Cd Length: 433  Bit Score: 823.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  20 LKDQDRIFTNLYNDFGTGIDAAERRGDWYRTKDILLKGHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKKKqDDRPSYI 99
Cdd:PRK13596   2 LKDKDRIFTNLYGLQDWSLKGAKKRGDWDGTKAILDKGRDWIIEEMKASGLRGRGGAGFPTGLKWSFMPKES-DGRPHYL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 100 VVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWDF 179
Cdd:PRK13596  81 VVNADESEPGTCKDRDILRHDPHKLIEGCLIASFAMGAHAAYIYIRGEFIREREALQAAIDEAYEAGLIGKNACGSGWDF 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 180 DLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKGNAGT 259
Cdd:PRK13596 161 DIYVHHGAGAYICGEETALLESLEGKKGQPRLKPPFPANVGLYGCPTTVNNVESIAVVPTILRRGAAWFASIGRPNNTGT 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 260 KLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWDNLLCVIPGGSSCPLIPKHICDDILMDYDALKEAQTGLGTAA 339
Cdd:PRK13596 241 KLFCISGHVNKPCNVEEAMGIPFRELIEKHAGGVRGGWDNLLAVIPGGSSVPLIPAEQCEDAIMDFDSLRAVGSGLGTAA 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 340 VIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAAW 419
Cdd:PRK13596 321 VIVMDKSTDIIKAIARLSYFYKHESCGQCTPCREGTGWMWRVMERMVKGRAQKREIDMLLDVTKQIEGHTICALGDAAAW 400
                        410       420
                 ....*....|....*....|
gi 157864056 420 PVQGLIRHFKPLMEERIERF 439
Cdd:PRK13596 401 PIQGLIRHFRPEIEERIDQY 420
PLN03132 PLN03132
NADH dehydrogenase (ubiquinone) flavoprotein 1; Provisional
14-442 0e+00

NADH dehydrogenase (ubiquinone) flavoprotein 1; Provisional


Pssm-ID: 178678 [Multi-domain]  Cd Length: 461  Bit Score: 770.58  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  14 ERVHGHLKDQDRIFTNLYNDFGTGIDAAERRGDWYRTKDILLKGHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKKkQD 93
Cdd:PLN03132  27 KTHFGGLKDEDRIFTNLYGLHDPFLKGAMKRGDWHRTKDLVLKGPDWIVNEMKKSGLRGRGGAGFPSGLKWSFMPKV-SD 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  94 DRPSYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNAC 173
Cdd:PLN03132 106 GRPSYLVVNADESEPGTCKDREIMRHDPHKLLEGCLIAGVGMRARAAYIYIRGEYVNERLNLERARHEAYAAGLLGKNAC 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 174 GSGWDFDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGR 253
Cdd:PLN03132 186 GSGYDFDVYIHYGAGAYICGEETALLESLEGKQGKPRLKPPFPANVGLYGCPTTVTNVETVAVSPTILRRGPEWFASFGR 265
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 254 KGNAGTKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWDNLLCVIPGGSSCPLIPKHICDDILMDYDALKEAQT 333
Cdd:PLN03132 266 KNNAGTKLFCISGHVNKPCTVEEEMSIPLKELIERHCGGVRGGWDNLLAIIPGGSSVPLLPKKICDDVLMDFDALKAVQS 345
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 334 GLGTAAVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICAL 413
Cdd:PLN03132 346 GLGTAAVIVMDKSTDVVDAIARLSYFYKHESCGQCTPCREGTGWLWDIMERMKVGNAKLEEIDMLQEVTKQIEGHTICAL 425
                        410       420
                 ....*....|....*....|....*....
gi 157864056 414 GTAAAWPVQGLIRHFKPLMEERIERFWEA 442
Cdd:PLN03132 426 GDAAAWPVQGLIRHFRPELERRIKERAER 454
nuoF_fam TIGR01959
NADH-quinone oxidoreductase, F subunit; This model describes the F chain of complexes that ...
25-436 0e+00

NADH-quinone oxidoreductase, F subunit; This model describes the F chain of complexes that resemble NADH-quinone oxidoreductases. The electron acceptor is a quinone, ubiquinone, in mitochondria and most bacteria, including Escherichia coli, where the recommended gene symbol is nuoF. This family does not have any members in chloroplast or cyanobacteria, where the quinone may be plastoquinone and NADH may be replaced by NADPH, nor in Methanosarcina, where NADH is replaced by F420H2. [Energy metabolism, Electron transport]


Pssm-ID: 131014  Cd Length: 411  Bit Score: 651.71  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   25 RIFTNLYNDFGTGIDAAERRGDWYRTKDILLK-GHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKKkQDDRPSYIVVNC 103
Cdd:TIGR01959   1 VLTTNLDNPESWTLEEYEKRGGYDALRKALEEmSPDDIIEEVKDSGLRGRGGAGFPTGLKWSFMPKD-DSPKPKYLVCNA 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  104 DESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWDFDLYT 183
Cdd:TIGR01959  80 DESEPGTCKDRDLMEFDPHQLIEGMIIAAYAIGAHRGYIYIRGEFIKEAENLEAAIAEAYAAGLLGKNILGSGFDFELFV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  184 YRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKGNAGTKLFC 263
Cdd:TIGR01959 160 HRGAGAYICGEETALLESLEGKRGQPRLKPPFPAVFGLYGKPTVINNVETLASVPAILRRGADWYRKLGKEKSPGTKLFS 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  264 ISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGWdNLLCVIPGGSSCPLIPKHICDDILMDYDALKEAQTGLGTAAVIVM 343
Cdd:TIGR01959 240 VSGHVNKPGNYELPLGTPLRELLEDYAGGMRGGW-KLKAVIPGGSSTPVLPAEQHLDAPMDYDSLAAAGSMLGTGAVIVM 318
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  344 DKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAAWPVQG 423
Cdd:TIGR01959 319 DESTCMVKAVRRLSEFYAHESCGQCTPCREGTGWMVKILERIEEGEGTKEDIDLLLSVCKQIEGKTICALGDAAAWPVQS 398
                         410
                  ....*....|...
gi 157864056  424 LIRHFKPLMEERI 436
Cdd:TIGR01959 399 AIKHFRDEFEAHI 411
NuoF COG1894
NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) [Energy production and ...
21-437 0e+00

NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) [Energy production and conversion]; NADH:ubiquinone oxidoreductase, NADH-binding 51 kD subunit (chain F) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 441498 [Multi-domain]  Cd Length: 418  Bit Score: 651.69  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  21 KDQDRI-FTNLYNDFGTGIDAAERRGDWYRTKDILLK-GHDWVINEIKASGLRGRGGAGFPSGLKWSFMPKkkQDDRPSY 98
Cdd:COG1894    1 KKQTRVlLRNCGIIDPESLEDYIARGGYQALRKALTEmTPEEVIEEVKDSGLRGRGGAGFPTGLKWSFVPK--APGDPKY 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  99 IVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWD 178
Cdd:COG1894   79 LVCNADEGEPGTFKDRSLLEGDPHQLIEGMIIAAYAIGATKGYIYIRGEYPLAIERLEKAIEEAREAGLLGKNILGSGFD 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 179 FDLYTYRGAGAYICGEETAMIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKGNAG 258
Cdd:COG1894  159 FDIEVHRGAGAYICGEETALLESLEGKRGQPRLKPPFPAVSGLWGKPTVVNNVETLANVPHIIRNGAEWFASIGTEKSKG 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 259 TKLFCISGHVNRPCTVEEEMSMPLRELLERHAGGVRGGwDNLLCVIPGGSSCPLIPKHiCDDILMDYDALKEAQTGLGTA 338
Cdd:COG1894  239 TKLFSLSGHVKNPGLYEVPMGTTLRELIYDIGGGIRGG-RKLKAVQPGGPSGGCLPAE-HLDTPMDYESLAAAGSMLGSG 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 339 AVIVMDKSTDVINAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAA 418
Cdd:COG1894  317 GMIVMDETTCMVDVARFFLEFYAHESCGKCTPCREGTGWMLEILDRIEAGEGTEEDLDLLEDLADTIKGTSLCALGDAAP 396
                        410
                 ....*....|....*....
gi 157864056 419 WPVQGLIRHFKPLMEERIE 437
Cdd:COG1894  397 NPVLSTLKYFRDEFEAHIK 415
PRK11278 PRK11278
NADH-quinone oxidoreductase subunit NuoF;
46-438 8.18e-110

NADH-quinone oxidoreductase subunit NuoF;


Pssm-ID: 236891 [Multi-domain]  Cd Length: 448  Bit Score: 332.54  E-value: 8.18e-110
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  46 DWYRTKD------ILLKG--HDWVINEIKASGLRGRGGAGFPSGLKWSFMPKKkQDDRPSYIVVNCDESEPGTCKDREIM 117
Cdd:PRK11278  28 DEYRSKNgyegarKALTGmsPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKD-ESMNIRYLLCNADEMEPGTYKDRLLM 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 118 RHEPHKVVEGALLAGFAMRARYGYIYIRGEFYNEWRSVEKAIHEAYEKGYLGKNACGSGWDFDLYTYRGAGAYICGEETA 197
Cdd:PRK11278 107 EQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNIMGTGFDFELFVHTGAGRYICGEETA 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 198 MIASIEGGQGKPRLKPPFPANVGLYGCPTTVTNCETVAVSPTIIRRGPQWFAQFGRKG--NAGTKLFCISGHVNRPCTVE 275
Cdd:PRK11278 187 LINSLEGRRANPRSKPPFPATSGVWGKPTCVNNVETLCNVPAILANGVEWYQNISKGKskDAGTKLMGFSGRVKNPGLWE 266
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 276 EEMSMPLRELLERHAGGVRGGWdNLLCVIPGGSSCP-LIPKHIcdDILMDYDALKEAQTGLGTAAVIVMDKSTDVINAIE 354
Cdd:PRK11278 267 LPFGTTAREILEDYAGGMRDGL-KFKAWQPGGAGTDfLTEAHL--DLPMEFESIGKAGSRLGTALAMAVDHEINMVSLVR 343
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056 355 RLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQM-EGRSICALGTAAAWPVQGLIRHFKPLME 433
Cdd:PRK11278 344 NLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLgPGKTFCAHAPGAVEPLQSAIKYFREEFE 423

                 ....*
gi 157864056 434 ERIER 438
Cdd:PRK11278 424 AGIKQ 428
Complex1_51K pfam01512
Respiratory-chain NADH dehydrogenase 51 Kd subunit;
65-235 2.45e-56

Respiratory-chain NADH dehydrogenase 51 Kd subunit;


Pssm-ID: 460237 [Multi-domain]  Cd Length: 150  Bit Score: 184.25  E-value: 2.45e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056   65 IKASGLRGRGGAGFPSGLKWSFMPKKKQDdrpsYIVVNCDESEPGTCKDREIMRHEPHKVVEGALLAGFAMRARYGYIYI 144
Cdd:pfam01512   1 VKEAGIVGRGGAGFPTHVKLSPPPKKKIK----YLIVNGAECEPGLTKDRRLMRERPHEIIEGIKIAAYALGAKRGVIGI 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  145 RGEFYNEWRSVEKAIHEAYEKGylgknacgsgwdFDLYTYRGAGAYICGEETAMIASIEGGqGKPRLKPpfPANVGLygc 224
Cdd:pfam01512  77 RDEKPEAIAALEKAIAEARAAG------------FDIEVHRGAGAYPCGEEKALIYSLTGR-GVPRGKP--PADVGV--- 138
                         170
                  ....*....|.
gi 157864056  225 ptTVTNCETVA 235
Cdd:pfam01512 139 --VVNNVETLA 147
NADH_4Fe-4S pfam10589
NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;
352-435 1.78e-38

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;


Pssm-ID: 463160 [Multi-domain]  Cd Length: 85  Bit Score: 134.91  E-value: 1.78e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  352 AIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEIYTLWDVSKQMEGRSICALGTAAAWPVQGLIRHFKPL 431
Cdd:pfam10589   2 VARRFLEFYAHESCGKCTPCREGTKWLAEILERIVDGEGTEEDLDLLEELARTIKGRSLCGLGDGAANPVLSALRYFRDE 81

                  ....
gi 157864056  432 MEER 435
Cdd:pfam10589  82 FEAH 85
NADH_4Fe-4S smart00928
NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;
350-395 1.78e-18

NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;


Pssm-ID: 197996 [Multi-domain]  Cd Length: 46  Bit Score: 78.72  E-value: 1.78e-18
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 157864056   350 INAIERLSQFYMHESCGQCTPCREGSPWLDKMMKRFVNGNAKKEEI 395
Cdd:smart00928   1 VDAARRLMEFYAHESCGKCTPCREGTGWLLEILDRIEEGEGTEEDL 46
RnfC COG4656
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and ...
61-142 2.51e-12

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfC subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 443694 [Multi-domain]  Cd Length: 451  Bit Score: 68.63  E-value: 2.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 157864056  61 VINEIKASGLRGRGGAGFPSGLKWSFMPKKKQDdrpsYIVVNCDESEPG-TCKDReIMRHEPHKVVEGALLAGFAMRARY 139
Cdd:COG4656  124 IIERIREAGIVGLGGAGFPTHVKLSPPPDKKID----TLIINGAECEPYlTCDDR-LMRERAEEIIEGIRILMKALGAKK 198

                 ...
gi 157864056 140 GYI 142
Cdd:COG4656  199 VII 201
rnfC TIGR01945
electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in ...
61-127 5.07e-07

electron transport complex, RnfABCDGE type, C subunit; The six subunit complex RnfABCDGE in Rhodobacter capsulatus encodes an apparent NADH oxidoreductase responsible for electron transport to nitrogenase, necessary for nitrogen fixation. A closely related complex in E. coli, RsxABCDGE (Reducer of SoxR), reduces the 2Fe-2S-containing superoxide sensor SoxR, active as a transcription factor when oxidized. This family of putative NADH oxidoreductase complexes exists in many of the same species as the related NQR, a Na(+)-translocating NADH-quinone reductase, but is distinct. This model describes the C subunit. [Energy metabolism, Electron transport]


Pssm-ID: 273888 [Multi-domain]  Cd Length: 435  Bit Score: 51.96  E-value: 5.07e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157864056   61 VINEIKASGLRGRGGAGFPSGLKWSFMPKKKQDdrpsYIVVNCDESEPG-TCKDReIMRHEPHKVVEG 127
Cdd:TIGR01945 124 ILEKIRAAGIVGLGGATFPTHVKLNPPPEKKIE----TLIINGAECEPYlTCDDR-LMRERAEEIIGG 186
SLBB pfam10531
SLBB domain;
262-311 7.47e-05

SLBB domain;


Pssm-ID: 463136 [Multi-domain]  Cd Length: 56  Bit Score: 40.34  E-value: 7.47e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 157864056  262 FCISGHVNRPCTVEEEMSMPLRELLErHAGGVRGGWDNLLCVI----PGGSSCP 311
Cdd:pfam10531   2 VTVTGEVKRPGNYEVPIGTTLSDLIE-LAGGFTDDADLDINLRrlkrPGGPMMG 54
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
52-128 5.75e-04

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 42.63  E-value: 5.75e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 157864056  52 DILLKGHDWVINEIKASGLRGRGGAGFPSGLKWSfmPKkkqDDRPSYIVVNCDESEPG-TCKDReIMRHEPHKVVEGA 128
Cdd:PRK05035 121 DYRQLSPEELIERIRQAGIAGLGGAGFPTAVKLQ--PG---GDKIETLIINGAECEPYiTADDR-LMRERADEIIEGI 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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