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Conserved domains on  [gi|145353610|ref|XP_001421100|]
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predicted protein [Ostreococcus lucimarinus CCE9901]

Protein Classification

PLN00208 family protein( domain architecture ID 10010700)

PLN00208 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PLN00208 PLN00208
translation initiation factor (eIF); Provisional
 1-129 6.30e-72

translation initiation factor (eIF); Provisional


:

Pssm-ID: 177798  Cd Length: 145  Bit Score: 211.96  E-value: 6.30e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   1 MPKSnsKGKGGKNRRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIIL 80
Cdd:PLN00208   1 MPKN--KGKGGKNRKRGKNEADDEKRELIFKEDGQEYAQVLRMLGNGRCEALCIDGTKRLCHIRGKMRKKVWIAAGDIIL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 145353610  81 LGLRDFQDEKADVILKYLADEARSLKAYGELPDTFRVNDT---DTFEEERDE 129
Cdd:PLN00208  79 VGLRDYQDDKADVILKYMPDEARLLKAYGELPENTRLNEGiagDLDEEEDGE 130
 
Name Accession Description Interval E-value
PLN00208 PLN00208
translation initiation factor (eIF); Provisional
 1-129 6.30e-72

translation initiation factor (eIF); Provisional


Pssm-ID: 177798  Cd Length: 145  Bit Score: 211.96  E-value: 6.30e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   1 MPKSnsKGKGGKNRRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIIL 80
Cdd:PLN00208   1 MPKN--KGKGGKNRKRGKNEADDEKRELIFKEDGQEYAQVLRMLGNGRCEALCIDGTKRLCHIRGKMRKKVWIAAGDIIL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 145353610  81 LGLRDFQDEKADVILKYLADEARSLKAYGELPDTFRVNDT---DTFEEERDE 129
Cdd:PLN00208  79 VGLRDYQDDKADVILKYMPDEARLLKAYGELPENTRLNEGiagDLDEEEDGE 130
S1_IF1A cd05793
S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A ...
 35-111 9.53e-42

S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A in archaea, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. IF1A is essential for translation initiation. eIF1A acts synergistically with eIF1 to mediate assembly of ribosomal initiation complexes at the initiation codon and maintain the accuracy of this process by recognizing and destabilizing aberrant preinitiation complexes from the mRNA. Without eIF1A and eIF1, 43S ribosomal preinitiation complexes can bind to the cap-proximal region, but are unable to reach the initiation codon. eIF1a also enhances the formation of 5'-terminal complexes in the presence of other translation initiation factors. This protein family is only found in eukaryotes and archaea.


Pssm-ID: 240219  Cd Length: 77  Bit Score: 133.42  E-value: 9.53e-42
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145353610  35 QEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILKYLADEARSLKAYGEL 111
Cdd:cd05793    1 EEYGQVEKMLGNGRLEVRCFDGKKRLCRIRGKMRKRVWINEGDIVLVAPWDFQDDKADIIYKYTPDEVRWLKRKGEL 77
eIF1a smart00652
eukaryotic translation initiation factor 1A;
30-112 4.17e-41

eukaryotic translation initiation factor 1A;


Pssm-ID: 128900  Cd Length: 83  Bit Score: 131.99  E-value: 4.17e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610    30 FKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILKYLADEARSLKAYG 109
Cdd:smart00652   1 FKEDGQEIAQVVKMLGNGRLEVMCADGKERLARIPGKMRKKVWIRRGDIVLVDPWDFQDVKADIIYKYTKDEVRWLKKEG 80


                   ...
gi 145353610   110 ELP 112
Cdd:smart00652  81 ELP 83
eIF-1A TIGR00523
eukaryotic/archaeal initiation factor 1A; Recommended nomenclature: eIF-1A for eukaryotes, ...
 16-112 5.05e-34

eukaryotic/archaeal initiation factor 1A; Recommended nomenclature: eIF-1A for eukaryotes, aIF-1A for Archaea. Also called eIF-4C [Protein synthesis, Translation factors]


Pssm-ID: 273118  Cd Length: 98  Bit Score: 114.58  E-value: 5.05e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   16 RGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVIL 95
Cdd:TIGR00523   1 RGKQDSDGPRVRLPYKEEGEIYGVITQMLGAGRVKVRCFDGNKRLARIPGKLRKKIWIREGDVVLVKPWEFQDDKCDIVW 80

                          90
                  ....*....|....*..
gi 145353610   96 KYLADEARSLKAYGELP 112
Cdd:TIGR00523  81 RYTLTEVEWLKRKGYLK 97
eIF-1a pfam01176
Translation initiation factor 1A / IF-1; This family includes both the eukaryotic translation ...
 35-96 2.11e-23

Translation initiation factor 1A / IF-1; This family includes both the eukaryotic translation factor eIF-1A and the bacterial translation initiation factor IF-1.


Pssm-ID: 460099  Cd Length: 62  Bit Score: 86.28  E-value: 2.11e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 145353610   35 QEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILK 96
Cdd:pfam01176   1 EVIGKVVEALGNNLFEVELDNGHTRLAHIPGKMRNRIWIKRGDYVLVEPSPYDLTKGRIVYR 62
InfA COG0361
Translation initiation factor IF-1 [Translation, ribosomal structure and biogenesis]; ...
 31-97 4.16e-17

Translation initiation factor IF-1 [Translation, ribosomal structure and biogenesis]; Translation initiation factor IF-1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440130  Cd Length: 73  Bit Score: 70.52  E-value: 4.16e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 145353610  31 KEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRK-KVWVNTGDIILLGLRDFQDEKADVILKY 97
Cdd:COG0361    5 EDLIEVEGVVEEVLPNARFRVRLENGHERLARISGKMRKnRIRILPGDRVLVEPSPYDLTKGRIVYRY 72
 
Name Accession Description Interval E-value
PLN00208 PLN00208
translation initiation factor (eIF); Provisional
 1-129 6.30e-72

translation initiation factor (eIF); Provisional


Pssm-ID: 177798  Cd Length: 145  Bit Score: 211.96  E-value: 6.30e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   1 MPKSnsKGKGGKNRRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIIL 80
Cdd:PLN00208   1 MPKN--KGKGGKNRKRGKNEADDEKRELIFKEDGQEYAQVLRMLGNGRCEALCIDGTKRLCHIRGKMRKKVWIAAGDIIL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 145353610  81 LGLRDFQDEKADVILKYLADEARSLKAYGELPDTFRVNDT---DTFEEERDE 129
Cdd:PLN00208  79 VGLRDYQDDKADVILKYMPDEARLLKAYGELPENTRLNEGiagDLDEEEDGE 130
PTZ00329 PTZ00329
eukaryotic translation initiation factor 1A; Provisional
 1-128 3.53e-71

eukaryotic translation initiation factor 1A; Provisional


Pssm-ID: 185558  Cd Length: 155  Bit Score: 210.44  E-value: 3.53e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   1 MPKSnsKGKGGKNRRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIIL 80
Cdd:PTZ00329   1 MPKN--KGKGGKNRRRGKNDNEGEKRELVFKEEGQEYAQVLRMLGNGRLEAYCFDGVKRLCHIRGKMRKRVWINIGDIIL 78

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 145353610  81 LGLRDFQDEKADVILKYLADEARSLKAYGELPDTFRVNDTDTFEEERD 128
Cdd:PTZ00329  79 VSLRDFQDSKADVILKYTPDEARALKQHGELPETAKINETDIFDDEGD 126
S1_IF1A cd05793
S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A ...
 35-111 9.53e-42

S1_IF1A: Translation initiation factor IF1A, also referred to as eIF1A in eukaryotes and aIF1A in archaea, S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. IF1A is essential for translation initiation. eIF1A acts synergistically with eIF1 to mediate assembly of ribosomal initiation complexes at the initiation codon and maintain the accuracy of this process by recognizing and destabilizing aberrant preinitiation complexes from the mRNA. Without eIF1A and eIF1, 43S ribosomal preinitiation complexes can bind to the cap-proximal region, but are unable to reach the initiation codon. eIF1a also enhances the formation of 5'-terminal complexes in the presence of other translation initiation factors. This protein family is only found in eukaryotes and archaea.


Pssm-ID: 240219  Cd Length: 77  Bit Score: 133.42  E-value: 9.53e-42
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 145353610  35 QEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILKYLADEARSLKAYGEL 111
Cdd:cd05793    1 EEYGQVEKMLGNGRLEVRCFDGKKRLCRIRGKMRKRVWINEGDIVLVAPWDFQDDKADIIYKYTPDEVRWLKRKGEL 77
eIF1a smart00652
eukaryotic translation initiation factor 1A;
30-112 4.17e-41

eukaryotic translation initiation factor 1A;


Pssm-ID: 128900  Cd Length: 83  Bit Score: 131.99  E-value: 4.17e-41
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610    30 FKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILKYLADEARSLKAYG 109
Cdd:smart00652   1 FKEDGQEIAQVVKMLGNGRLEVMCADGKERLARIPGKMRKKVWIRRGDIVLVDPWDFQDVKADIIYKYTKDEVRWLKKEG 80


                   ...
gi 145353610   110 ELP 112
Cdd:smart00652  81 ELP 83
eIF-1A TIGR00523
eukaryotic/archaeal initiation factor 1A; Recommended nomenclature: eIF-1A for eukaryotes, ...
 16-112 5.05e-34

eukaryotic/archaeal initiation factor 1A; Recommended nomenclature: eIF-1A for eukaryotes, aIF-1A for Archaea. Also called eIF-4C [Protein synthesis, Translation factors]


Pssm-ID: 273118  Cd Length: 98  Bit Score: 114.58  E-value: 5.05e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610   16 RGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVIL 95
Cdd:TIGR00523   1 RGKQDSDGPRVRLPYKEEGEIYGVITQMLGAGRVKVRCFDGNKRLARIPGKLRKKIWIREGDVVLVKPWEFQDDKCDIVW 80

                          90
                  ....*....|....*..
gi 145353610   96 KYLADEARSLKAYGELP 112
Cdd:TIGR00523  81 RYTLTEVEWLKRKGYLK 97
S1_IF1A_like cd04456
S1_IF1A_like: Translation initiation factor IF1A-like, S1-like RNA-binding domain. IF1A is ...
 35-111 1.66e-32

S1_IF1A_like: Translation initiation factor IF1A-like, S1-like RNA-binding domain. IF1A is also referred to as eIF1A in eukaryotes and aIF1A in archaea. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. IF1A is essential for translation initiation. eIF1A acts synergistically with eIF1 to mediate assembly of ribosomal initiation complexes at the initiation codon and maintain the accuracy of this process by recognizing and destabilizing aberrant preinitiation complexes from the mRNA. Without eIF1A and eIF1, 43S ribosomal preinitiation complexes can bind to the cap-proximal region, but are unable to reach the initiation codon. eIF1a also enhances the formation of 5'-terminal complexes in the presence of other translation initiation factors. This protein family is only found in eukaryotes and archaea.


Pssm-ID: 239903  Cd Length: 78  Bit Score: 109.95  E-value: 1.66e-32
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 145353610  35 QEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDF-QDEKADVILKYLADEARSLKAYGEL 111
Cdd:cd04456    1 QQIVRVLRMLGNNRHEVECADGQRRLVSIPGKLRKNIWIKRGDFLIVDPIEEgEDVKADIIFVYCKDHVRSLKKEGFL 78
PRK04012 PRK04012
translation initiation factor IF-1A; Provisional
 14-112 3.33e-26

translation initiation factor IF-1A; Provisional


Pssm-ID: 179708  Cd Length: 100  Bit Score: 94.63  E-value: 3.33e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 145353610  14 RRRGKGGGEDEKRELIFKEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADV 93
Cdd:PRK04012   1 MKKKQDDEEVTRVRLPMPEEGEVFGVVEQMLGANRVRVRCMDGVERMGRIPGKMKKRMWIREGDVVIVAPWDFQDEKADI 80

                         90
                 ....*....|....*....
gi 145353610  94 ILKYLADEARSLKAYGELP 112
Cdd:PRK04012  81 IWRYTKPQVDWLRRKGYIS 99
eIF-1a pfam01176
Translation initiation factor 1A / IF-1; This family includes both the eukaryotic translation ...
 35-96 2.11e-23

Translation initiation factor 1A / IF-1; This family includes both the eukaryotic translation factor eIF-1A and the bacterial translation initiation factor IF-1.


Pssm-ID: 460099  Cd Length: 62  Bit Score: 86.28  E-value: 2.11e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 145353610   35 QEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRKKVWVNTGDIILLGLRDFQDEKADVILK 96
Cdd:pfam01176   1 EVIGKVVEALGNNLFEVELDNGHTRLAHIPGKMRNRIWIKRGDYVLVEPSPYDLTKGRIVYR 62
InfA COG0361
Translation initiation factor IF-1 [Translation, ribosomal structure and biogenesis]; ...
 31-97 4.16e-17

Translation initiation factor IF-1 [Translation, ribosomal structure and biogenesis]; Translation initiation factor IF-1 is part of the Pathway/BioSystem: Translation factors


Pssm-ID: 440130  Cd Length: 73  Bit Score: 70.52  E-value: 4.16e-17
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 145353610  31 KEDGQEYAQVLRMLGNGRLEAQCIDGVKRLCHIRGKMRK-KVWVNTGDIILLGLRDFQDEKADVILKY 97
Cdd:COG0361    5 EDLIEVEGVVEEVLPNARFRVRLENGHERLARISGKMRKnRIRILPGDRVLVEPSPYDLTKGRIVYRY 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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