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Conserved domains on  [gi|297291543|ref|XP_001083841|]
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protein-L-isoaspartate(D-aspartate) O-methyltransferase isoform X1 [Macaca mulatta]

Protein Classification

protein-L-isoaspartate O-methyltransferase( domain architecture ID 12014395)

protein-L-isoaspartate O-methyltransferase catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 7.72e-112

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


:

Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 321.24  E-value: 7.72e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  142 DVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 297291543  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 7.72e-112

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 321.24  E-value: 7.72e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  142 DVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 297291543  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-281 3.78e-72

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 220.85  E-value: 3.78e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEG 137
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVAMMTELL--ELKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  138 AKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVG 217
Cdd:TIGR00080  79 MKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVT 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 297291543  218 AAAPVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKEKQW 281
Cdd:TIGR00080 154 AAGPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-278 1.30e-52

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 170.97  E-value: 1.30e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGS 145
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAIMCELL--DLKEGMKVLEIGT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 146 GSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQ 225
Cdd:PRK13942  86 GSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 297291543 226 ALIDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK13942 161 PLIEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-275 3.11e-51

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 166.80  E-value: 3.11e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGSG 146
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVARMLEAL--DLKPGDRVLEIGTG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 147 SGILTACFARMVGctgKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQA 226
Cdd:COG2518   77 SGYQAAVLARLAG---RVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEA 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 297291543 227 LIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGsVKMKPLMGVIYVPLT 275
Cdd:COG2518  149 LLEQLAPGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 139-241 9.86e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 46.65  E-value: 9.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 139 KALDVGSGSGILTACFARMVGCtgKVIGIDhikelVDDSINNVRKDDPTLLSSGRVQLVVGDGRMG-YAEEAPYDAIHVG 217
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGA--RVTGVD-----ISPVALELARKAAAALLADNVEVLKGDAEELpPEADESFDVIISD 73

                         90       100       110
                 ....*....|....*....|....*....|.
gi 297291543 218 AAAPVV---PQALIDQ----LKPGGRLILPV 241
Cdd:cd02440   74 PPLHHLvedLARFLEEarrlLKPGGVLVLTL 104
 
Name Accession Description Interval E-value
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
66-274 7.72e-112

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 321.24  E-value: 7.72e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   66 ASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYAKC----NPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKAL 141
Cdd:pfam01135   1 NRNEALIENLKNYGVIKSDKVAEAMLAVDREEFVPEsfksYAYEDIPLSIGYGQTISAPHMHAMMLELL--ELKPGMRVL 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  142 DVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDPTllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAAP 221
Cdd:pfam01135  79 EIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLE-----NVIVVVGDGRQGWPEFAPYDAIHVGAAAP 153

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 297291543  222 VVPQALIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPL 274
Cdd:pfam01135 154 EIPEALIDQLKEGGRLVIPVGP-NGNQVLQQFDKRNDGSVVIKDLEGVRFVPL 205
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 62-281 3.78e-72

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 220.85  E-value: 3.78e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   62 KSGGASHSELIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEG 137
Cdd:TIGR00080   1 MDLESQKKALIDKLINEGYIKSKRVIDALLSVPREEFVpehfKEYAYVDTPLEIGYGQTISAPHMVAMMTELL--ELKPG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  138 AKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVG 217
Cdd:TIGR00080  79 MKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRK-----LGLDNVIVIVGDGTQGWEPLAPYDRIYVT 153

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 297291543  218 AAAPVVPQALIDQLKPGGRLILPVGPagGNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKEKQW 281
Cdd:TIGR00080 154 AAGPKIPEALIDQLKEGGILVMPVGE--YLQVLKRAEK-RGGEIIIKDVEPVAFVPLVGGEGFQ 214
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 70-278 1.30e-52

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 170.97  E-value: 1.30e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  70 ELIHNLRKNGIIKTDKVFEVMLATDR----SHYAKCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGS 145
Cdd:PRK13942   8 RVIEELIREGYIKSKKVIDALLKVPRhlfvPEYLEEYAYVDTPLEIGYGQTISAIHMVAIMCELL--DLKEGMKVLEIGT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 146 GSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQ 225
Cdd:PRK13942  86 GSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKK-----LGYDNVEVIVGDGTLGYEENAPYDRIYVTAAGPDIPK 160

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 297291543 226 ALIDQLKPGGRLILPVGPAggNQMLEQYDKlQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK13942 161 PLIEQLKDGGIMVIPVGSY--SQELIRVEK-DNGKIIKKKLGEVAFVPLIGKN 210
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 75-275 3.11e-51

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 166.80  E-value: 3.11e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  75 LRKNGIiKTDKVFEVMLATDR--------SHYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGSG 146
Cdd:COG2518    4 LRPRGV-TDPRVLDAMRAVPRelfvpealRELA----YADRALPIGHGQTISQPYIVARMLEAL--DLKPGDRVLEIGTG 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 147 SGILTACFARMVGctgKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQA 226
Cdd:COG2518   77 SGYQAAVLARLAG---RVYSVERDPELAERARERLAA-----LGYDNVTVRVGDGALGWPEHAPFDRIIVTAAAPEVPEA 148

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 297291543 227 LIDQLKPGGRLILPVGPaGGNQMLEQYDKLQDGsVKMKPLMGVIYVPLT 275
Cdd:COG2518  149 LLEQLAPGGRLVAPVGE-GGVQRLVLITRTGDG-FERESLFEVRFVPLR 195
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
71-278 1.85e-45

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 152.28  E-value: 1.85e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  71 LIHNLRKNGIiKTDKVFEVMLATDRS--------HYAkcnpYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALD 142
Cdd:PRK00312  12 LVLRLRAEGI-LDERVLEAIEATPRElfvpeafkHKA----YENRALPIGCGQTISQPYMVARMTELL--ELKPGDRVLE 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 143 VGSGSGILTACFARMVGctgKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPV 222
Cdd:PRK00312  85 IGTGSGYQAAVLAHLVR---RVFSVERIKTLQWEAKRRLKQ-----LGLHNVSVRHGDGWKGWPAYAPFDRILVTAAAPE 156

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 297291543 223 VPQALIDQLKPGGRLILPVGpaGGNQMLEQYDKLQDGSVKMKPLMGVIYVPLTDKE 278
Cdd:PRK00312 157 IPRALLEQLKEGGILVAPVG--GEEQQLLTRVRKRGGRFEREVLEEVRFVPLVKGE 210
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 71-274 1.34e-32

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 119.15  E-value: 1.34e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  71 LIHNLRKNGIIKTDKVFEVMLATDRSHYA----KCNPYMDSPQSIGFQATISAPHMHAYALELLfdQLHEGAKALDVGSG 146
Cdd:PRK13944   5 LVEELVREGIIKSERVKKAMLSVPREEFVmpeyRMMAYEDRPLPLFAGATISAPHMVAMMCELI--EPRPGMKILEVGTG 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 147 SGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptLLSSGRVQLVVGDGRMGYAEEAPYDAIHVGAAAPVVPQA 226
Cdd:PRK13944  83 SGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIER----LGYWGVVEVYHGDGKRGLEKHAPFDAIIVTAAASTIPSA 158

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 297291543 227 LIDQLKPGGRLILPVGPAGGnQMLEQYDKLQDGsVKMKPLMGVIYVPL 274
Cdd:PRK13944 159 LVRQLKDGGVLVIPVEEGVG-QVLYKVVKRGEK-VEKRAITYVLFVPL 204
methyltran_FxLD TIGR04364
methyltransferase, FxLD system; Members of this family resemble occur regularly in the ...
 69-241 1.33e-19

methyltransferase, FxLD system; Members of this family resemble occur regularly in the vicinity of lantibiotic biosynthesis enzymes and their probable target, the FxLD family of putative ribosomal natural product precursor (TIGR04363). Members resemble protein-L-isoaspartate O-methyltransferase (TIGR00080) and a predicted methyltranserase, TIGR04188, of another putative peptide modification system.


Pssm-ID: 275158  Cd Length: 394  Bit Score: 87.42  E-value: 1.33e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543   69 SELIHNLRKNGIIKTDKVFEVMLATDRSHYAKCNP----YM----------DSPQSIgfqATISAPHMHAYALELLfdQL 134
Cdd:TIGR04364   6 AALVDELREDGVIRSPRVEAAFRTVPRHLFAPGAPlekaYAanravvtkrdEDGRAL---SSVSAPHIQAMMLEQA--GV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  135 HEGAKALDVGSGsGILTACFARMVGCTGKVIGIDHIKELVDDSinnvRKddptLLSS---GRVQLVVGDGRMGYAEEAPY 211
Cdd:TIGR04364  81 EPGMRVLEIGSG-GYNAALLAELVGPSGEVTTVDIDEDVTDRA----RA----CLAAagyPQVTVVLADAEAGVPELAPY 151

                         170       180       190
                  ....*....|....*....|....*....|
gi 297291543  212 DAIHVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR04364 152 DRIIVTVGAWDIPPAWLDQLAPGGRLVVPL 181
PRK13943 PRK13943
protein-L-isoaspartate O-methyltransferase; Provisional
 64-241 8.26e-19

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 237568 [Multi-domain]  Cd Length: 322  Bit Score: 84.51  E-value: 8.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  64 GGASHSELIHNLRKNGIikTDKVFEVMLATDRS-----HYAKCNPYMD----SPQSIGFQATISAPHMHAYALELLfdQL 134
Cdd:PRK13943   3 EFFMREKLFWILKKYGI--SDHIAKAFLEVPREefltkSYPLSYVYEDivlvSYDDGEEYSTSSQPSLMALFMEWV--GL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 135 HEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRMGYAEEAPYDAI 214
Cdd:PRK13943  79 DKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVRR-----LGIENVIFVCGDGYYGVPEFAPYDVI 153

                        170       180
                 ....*....|....*....|....*..
gi 297291543 215 HVGAAAPVVPQALIDQLKPGGRLILPV 241
Cdd:PRK13943 154 FVTVGVDEVPETWFTQLKEGGRVIVPI 180
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 134-238 3.87e-11

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 61.71  E-value: 3.87e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 134 LHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptLLSSGRVQLVVGDGRMGYAEEaPYDA 213
Cdd:COG2519   89 IFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLER----FGLPDNVELKLGDIREGIDEG-DVDA 163

                         90       100
                 ....*....|....*....|....*..
gi 297291543 214 IHVGAAAP--VVPQAlIDQLKPGGRLI 238
Cdd:COG2519  164 VFLDMPDPweALEAV-AKALKPGGVLV 189
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 128-239 7.16e-10

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 55.79  E-value: 7.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 128 ELLFDQLHEGAKALDVGSGSGILTACFARMvGCtgKVIGIDhikeLVDDSINNVRKddptLLSSGRVQLVVGDGRMGYAE 207
Cdd:COG2227   16 ALLARLLPAGGRVLDVGCGTGRLALALARR-GA--DVTGVD----ISPEALEIARE----RAAELNVDFVQGDLEDLPLE 84

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 297291543 208 EAPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG2227   85 DGSFDLVicsevleHLPDPAALL-RELARLLKPGGLLLL 122
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 126-239 1.40e-09

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 55.71  E-value: 1.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 126 ALELLFD--QLHEGAKALDVGSGSGILTACFARMVGCtgKVIGIDhikeLVDDSINNVRKDDPTLLSSGRVQLVVGDGRm 203
Cdd:COG2230   39 KLDLILRklGLKPGMRVLDIGCGWGGLALYLARRYGV--RVTGVT----LSPEQLEYARERAAEAGLADRVEVRLADYR- 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 297291543 204 GYAEEAPYDAI-------HVGAAA-PVVPQALIDQLKPGGRLIL 239
Cdd:COG2230  112 DLPADGQFDAIvsigmfeHVGPENyPAYFAKVARLLKPGGRLLL 155
methyltr_grsp TIGR04188
methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are ...
 134-246 2.86e-09

methyltransferase, ATP-grasp peptide maturase system; Members of this protein family are predicted SAM-dependent methyltransferases that regularly occur in the context of a putative peptide modification ATP-grasp enzyme (TIGR04187, related to enzymes of microviridin maturation) and a putative ribosomal peptide modification target (TIGR04186).


Pssm-ID: 275041  Cd Length: 363  Bit Score: 56.98  E-value: 2.86e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  134 LHEGAKALDVGSGSGILTACFARMVGcTGKVIGIDHIKELVDDSinnvrkdDPTLLSSG-RVQLVVGDGRMGYAEEAPYD 212
Cdd:TIGR04188 105 VEDGHRVLEIGTGTGYSAALLCHRLG-DDNVTSVEVDPGLAARA-------ASALAAAGyAPTVVTGDGLLGHPPRAPYD 176

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 297291543  213 AIHVGAAAPVVPQALIDQLKPGGRLILPVG---PAGG 246
Cdd:TIGR04188 177 RIIATCAVRRVPPAWLRQTRPGGVILTTLSgwlYGGG 213
PrmA COG2264
Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];
127-239 5.10e-09

Ribosomal protein L11 methylase PrmA [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441865 [Multi-domain]  Cd Length: 284  Bit Score: 55.95  E-value: 5.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 127 LELLFDQLHEGAKALDVGSGSGILtACFARMVGCtGKVIGIDhIKEL-VDDSINNVRKDDptllSSGRVQLVVGDGRmgy 205
Cdd:COG2264  139 LEALEKLLKPGKTVLDVGCGSGIL-AIAAAKLGA-KRVLAVD-IDPVaVEAARENAELNG----VEDRIEVVLGDLL--- 208

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 297291543 206 aEEAPYDAIhVgA---AAPVVPQA--LIDQLKPGGRLIL 239
Cdd:COG2264  209 -EDGPYDLV-V-AnilANPLIELApdLAALLKPGGYLIL 244
Tam COG4106
Trans-aconitate methyltransferase [Energy production and conversion];
136-239 6.26e-09

Trans-aconitate methyltransferase [Energy production and conversion];


Pssm-ID: 443282 [Multi-domain]  Cd Length: 100  Bit Score: 52.52  E-value: 6.26e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 136 EGAKALDVGSGSGILTACFARMVGCtGKVIGIDhikeLVDDSINNVRKDDPtllssgRVQLVVGDGRmGYAEEAPYDAIH 215
Cdd:COG4106    1 PPRRVLDLGCGTGRLTALLAERFPG-ARVTGVD----LSPEMLARARARLP------NVRFVVADLR-DLDPPEPFDLVV 68

                         90       100       110
                 ....*....|....*....|....*....|
gi 297291543 216 VGAA------APVVPQALIDQLKPGGRLIL 239
Cdd:COG4106   69 SNAAlhwlpdHAALLARLAAALAPGGVLAV 98
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 141-235 2.39e-08

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 50.64  E-value: 2.39e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  141 LDVGSGSGILTACFARMVGCtgKVIGIDHIKELVDDSINNVRKDDPtllssgRVQLVVGDGRMGYAEEAPYDAIHVGAAA 220
Cdd:pfam13649   2 LDLGCGTGRLTLALARRGGA--RVTGVDLSPEMLERARERAAEAGL------NVEFVQGDAEDLPFPDGSFDLVVSSGVL 73

                          90       100
                  ....*....|....*....|...
gi 297291543  221 PVVPQALIDQ--------LKPGG 235
Cdd:pfam13649  74 HHLPDPDLEAalreiarvLKPGG 96
SmtA COG0500
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ...
 126-269 3.05e-08

SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];


Pssm-ID: 440266 [Multi-domain]  Cd Length: 199  Bit Score: 52.61  E-value: 3.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 126 ALELLFDQLHEGAKALDVGSGSGILTACFARMVGctGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDGRM-G 204
Cdd:COG0500   16 ALLALLERLPKGGRVLDLGCGTGRNLLALAARFG--GRVIGIDLSPEAIALARARAAK-----AGLGNVEFLVADLAElD 88

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 297291543 205 YAEEAPYDAI-------HVgaaAPVVPQALID----QLKPGGRLILPVGPAGGNQMLEQYDKLQDGSVKMKPLMGV 269
Cdd:COG0500   89 PLPAESFDLVvafgvlhHL---PPEEREALLRelarALKPGGVLLLSASDAAAALSLARLLLLATASLLELLLLLR 161
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 123-239 5.84e-08

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 50.76  E-value: 5.84e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 123 HAYALELLfdQLHEGAKALDVGSGSGILTACFARMvgcTGKVIGIDHIKELVDDSINNVRKDDPtllssgRVQLVVGDG- 201
Cdd:COG2226   11 REALLAAL--GLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAAEAGL------NVEFVVGDAe 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 297291543 202 RMGYAEEApYDAIHVGAAAPVVP--QALIDQ----LKPGGRLIL 239
Cdd:COG2226   80 DLPFPDGS-FDLVISSFVLHHLPdpERALAEiarvLKPGGRLVV 122
AdoMet_MTases cd02440
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ...
 139-241 9.86e-07

S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).


Pssm-ID: 100107 [Multi-domain]  Cd Length: 107  Bit Score: 46.65  E-value: 9.86e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 139 KALDVGSGSGILTACFARMVGCtgKVIGIDhikelVDDSINNVRKDDPTLLSSGRVQLVVGDGRMG-YAEEAPYDAIHVG 217
Cdd:cd02440    1 RVLDLGCGTGALALALASGPGA--RVTGVD-----ISPVALELARKAAAALLADNVEVLKGDAEELpPEADESFDVIISD 73

                         90       100       110
                 ....*....|....*....|....*....|.
gi 297291543 218 AAAPVV---PQALIDQ----LKPGGRLILPV 241
Cdd:cd02440   74 PPLHHLvedLARFLEEarrlLKPGGVLVLTL 104
ubiE PRK00216
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ...
 137-239 1.40e-06

bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;


Pssm-ID: 234689 [Multi-domain]  Cd Length: 239  Bit Score: 48.23  E-value: 1.40e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 137 GAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDdsinNVRKDDPTLLSSGRVQLVVGDgrmgyAEEAPY----- 211
Cdd:PRK00216  52 GDKVLDLACGTGDLAIALAKAVGKTGEVVGLDFSEGMLA----VGREKLRDLGLSGNVEFVQGD-----AEALPFpdnsf 122

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 297291543 212 DAIHVGAAAPVVPQalIDQ--------LKPGGRL-IL 239
Cdd:PRK00216 123 DAVTIAFGLRNVPD--IDKalremyrvLKPGGRLvIL 157
CbiT TIGR02469
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes ...
 117-241 1.49e-06

precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; This model recognizes the CbiT methylase which is responsible, in part (along with CbiE), for methylating precorrin-6y (or cobalt-precorrin-6y) at both the 5 and 15 positions as well as the concomitant decarbozylation at C-12. In many organisms, this protein is fused to the CbiE subunit. The fused protein, when found in organisms catalyzing the oxidative version of the cobalamin biosynthesis pathway, is called CobL. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]


Pssm-ID: 274148 [Multi-domain]  Cd Length: 124  Bit Score: 46.55  E-value: 1.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  117 ISAPHMHAYALELLfdQLHEGAKALDVGSGSGILTACFARMVGcTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQL 196
Cdd:TIGR02469   2 MTKREVRALTLAKL--RLRPGDVLWDIGAGTGSVTIEAARLVP-NGRVYAIERNPEALDLIERNLRR-----FGVSNIVI 73

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 297291543  197 VVGDgrmgyAEEAPY------DAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:TIGR02469  74 VEGD-----APEAPEallpdpDAVFVGGSGgllQEILEAVERRLRPGGRIVLNA 122
PRK08317 PRK08317
hypothetical protein; Provisional
 124-239 1.49e-06

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 48.39  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 124 AYALELLfdQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINnvRKDDptllSSGRVQLVVGDG-R 202
Cdd:PRK08317   9 ARTFELL--AVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKE--RAAG----LGPNVEFVRGDAdG 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 297291543 203 MGYAEEApYDAI-------HVGAaapvvPQALIDQ----LKPGGRLIL 239
Cdd:PRK08317  81 LPFPDGS-FDAVrsdrvlqHLED-----PARALAEiarvLRPGGRVVV 122
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 134-239 1.79e-06

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 46.64  E-value: 1.79e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  134 LHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptlLSSGRVQLVVGDgrmgyAEEAP--- 210
Cdd:pfam13847   1 IDKGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDISEEAIEKARENAQK-----LGFDNVEFEQGD-----IEELPell 70

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 297291543  211 ----YD------AIHVGAAAPVVPQALIDQLKPGGRLIL 239
Cdd:pfam13847  71 eddkFDvvisncVLNHIPDPDKVLQEILRVLKPGGRLII 109
arsM PRK11873
arsenite methyltransferase;
131-183 6.76e-06

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 46.48  E-value: 6.76e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 297291543 131 FDQLHEGAKALDVGSGSGIltACF--ARMVGCTGKVIGIDHIKELVDDSINNVRK 183
Cdd:PRK11873  72 LAELKPGETVLDLGSGGGF--DCFlaARRVGPTGKVIGVDMTPEMLAKARANARK 124
prmA PRK00517
50S ribosomal protein L11 methyltransferase;
127-239 1.54e-05

50S ribosomal protein L11 methyltransferase;


Pssm-ID: 234786 [Multi-domain]  Cd Length: 250  Bit Score: 45.14  E-value: 1.54e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 127 LELLFDQLHEGAKALDVGSGSGILtACFARMVGCTgKVIGIDhIKEL-VDDSINNVRkddptlLSSGRVQLVVGDGrmgy 205
Cdd:PRK00517 110 LEALEKLVLPGKTVLDVGCGSGIL-AIAAAKLGAK-KVLAVD-IDPQaVEAARENAE------LNGVELNVYLPQG---- 176

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 297291543 206 aeEAPYDAIhVgA---AAPVVpqALIDQ----LKPGGRLIL 239
Cdd:PRK00517 177 --DLKADVI-V-AnilANPLL--ELAPDlarlLKPGGRLIL 211
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 126-241 4.65e-05

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 43.25  E-value: 4.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 126 ALELLFDQLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKddptLLSSGRVQLVVGDGRMGY 205
Cdd:PRK00377  30 ALALSKLRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEK----FGVLNNIVLIKGEAPEIL 105

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 297291543 206 AEEAP-YDAIHVGAAA---PVVPQALIDQLKPGGRLILPV 241
Cdd:PRK00377 106 FTINEkFDRIFIGGGSeklKEIISASWEIIKKGGRIVIDA 145
Methyltransf_11 pfam08241
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 141-239 6.98e-05

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 462406 [Multi-domain]  Cd Length: 94  Bit Score: 40.73  E-value: 6.98e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  141 LDVGSGSGILTACFARMVgctGKVIGIDHIKELVDDSINNVRKDDptllssgrVQLVVGDG-RMGYAEEApYDAIHVGAA 219
Cdd:pfam08241   1 LDVGCGTGLLTELLARLG---ARVTGVDISPEMLELAREKAPREG--------LTFVVGDAeDLPFPDNS-FDLVLSSEV 68

                          90       100
                  ....*....|....*....|....*.
gi 297291543  220 ---APVVPQAL--IDQ-LKPGGRLIL 239
Cdd:pfam08241  69 lhhVEDPERALreIARvLKPGGILII 94
PRK14968 PRK14968
putative methyltransferase; Provisional
 128-168 9.75e-05

putative methyltransferase; Provisional


Pssm-ID: 237872 [Multi-domain]  Cd Length: 188  Bit Score: 42.19  E-value: 9.75e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 297291543 128 ELLFDQLHE--GAKALDVGSGSGILTACFARMvgcTGKVIGID 168
Cdd:PRK14968  13 FLLAENAVDkkGDRVLEVGTGSGIVAIVAAKN---GKKVVGVD 52
Ubie_methyltran pfam01209
ubiE/COQ5 methyltransferase family;
136-238 3.21e-04

ubiE/COQ5 methyltransferase family;


Pssm-ID: 395966 [Multi-domain]  Cd Length: 228  Bit Score: 41.27  E-value: 3.21e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  136 EGAKALDVGSGSGILTACFARMVGCTGKVIGIDhikelvddsINnvrkddPTLLSSGR----------VQLVVGDGRMGY 205
Cdd:pfam01209  42 RGNKFLDVAGGTGDWTFGLSDSAGSSGKVVGLD---------IN------ENMLKEGEkkakeegkynIEFLQGNAEELP 106

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 297291543  206 AEEAPYDAIHVGAA---APVVPQALIDQ---LKPGGRLI 238
Cdd:pfam01209 107 FEDDSFDIVTISFGlrnFPDYLKVLKEAfrvLKPGGRVV 145
PLN02366 PLN02366
spermidine synthase
 181-235 5.63e-04

spermidine synthase


Pssm-ID: 215208 [Multi-domain]  Cd Length: 308  Bit Score: 40.78  E-value: 5.63e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 297291543 181 VRKDDPtllssgRVQLVVGDGR--MGYAEEAPYDAIHVGAAAPVVP-QALIDQ---------LKPGG 235
Cdd:PLN02366 140 VGFDDP------RVNLHIGDGVefLKNAPEGTYDAIIVDSSDPVGPaQELFEKpffesvaraLRPGG 200
MTS pfam05175
Methyltransferase small domain; This domain is found in ribosomal RNA small subunit ...
 131-239 7.69e-04

Methyltransferase small domain; This domain is found in ribosomal RNA small subunit methyltransferase C as well as other methyltransferases.


Pssm-ID: 428349 [Multi-domain]  Cd Length: 170  Bit Score: 39.50  E-value: 7.69e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543  131 FDQLHEGaKALDVGSGSGILTACFARMVGctgkvigiDHIKELVDDSINNVRKDDPTLLSSG--RVQLVVGDGRMGyAEE 208
Cdd:pfam05175  27 LPKDLSG-KVLDLGCGAGVLGAALAKESP--------DAELTMVDINARALESARENLAANGleNGEVVASDVYSG-VED 96

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 297291543  209 APYDAI------HVG-AAAPVVPQALI----DQLKPGGRLIL 239
Cdd:pfam05175  97 GKFDLIisnppfHAGlATTYNVAQRFIadakRHLRPGGELWI 138
COG4976 COG4976
Predicted methyltransferase, contains TPR repeat [General function prediction only];
121-239 1.13e-03

Predicted methyltransferase, contains TPR repeat [General function prediction only];


Pssm-ID: 444001 [Multi-domain]  Cd Length: 181  Bit Score: 39.21  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 121 HMHAYALELLFDQlhEGAKALDVGSGSGILTACFARMVgctGKVIGIDhikeLVDDSINNVRKddptllSSGRVQLVVGD 200
Cdd:COG4976   33 LLAEELLARLPPG--PFGRVLDLGCGTGLLGEALRPRG---YRLTGVD----LSEEMLAKARE------KGVYDRLLVAD 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 297291543 201 GRMGYAEEAPYDAI-------HVGAAAPVVpQALIDQLKPGGRLIL 239
Cdd:COG4976   98 LADLAEPDGRFDLIvaadvltYLGDLAAVF-AGVARALKPGGLFIF 142
RsmC COG2813
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ...
 128-239 1.15e-03

16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification


Pssm-ID: 442062 [Multi-domain]  Cd Length: 191  Bit Score: 39.02  E-value: 1.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 128 ELLFDQL--HEGAKALDVGSGSGILTACFARMVGcTGKVIGIDhIKEL-VDDSINNVRKDDPTllssgRVQLVVGDGRMG 204
Cdd:COG2813   39 RLLLEHLpePLGGRVLDLGCGYGVIGLALAKRNP-EARVTLVD-VNARaVELARANAAANGLE-----NVEVLWSDGLSG 111

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 297291543 205 YAEEaPYDAI------HVGAAAPV-VPQALIDQ----LKPGGRLIL 239
Cdd:COG2813  112 VPDG-SFDLIlsnppfHAGRAVDKeVAHALIADaarhLRPGGELWL 156
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 133-235 1.16e-03

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 39.01  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 297291543 133 QLHEGAKALDVGSGSGILTACFARMVGCTGKVIGIDHIKELVDDSINNVRKDDptllSSGRVQLVVGDGR--MGYAEEAP 210
Cdd:COG4122   13 RLLGAKRILEIGTGTGYSTLWLARALPDDGRLTTIEIDPERAAIARENFARAG----LADRIRLILGDALevLPRLADGP 88

                         90       100
                 ....*....|....*....|....*...
gi 297291543 211 YDAIHVGAAAPVVP---QALIDQLKPGG 235
Cdd:COG4122   89 FDLVFIDADKSNYPdylELALPLLRPGG 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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