|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
27-1043 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 844.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 27 KSISGTVTDDQGEAVISGTVKVKNGSTGTITDINGKYTLSVPSNATLVFSYIGYITQEFKVSelKSNVLNVVLQSDTKAL 106
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVK--GQKNLNITLKEDTQEL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 107 DEVVVVGYGTMRKSDLTGSISTAKGKDMLKAQSFNALDGLKGKVAGVNIFSNTGQPGGESRVIIRGISTINASASPLYVV 186
Cdd:TIGR04056 79 DEVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 187 DGVVMSN-FELLNPNDIESIEVLKDASSAAIYGARGANGVIMVTTKRGNAGKgVHVSYDGSLSIGKMARKIDVMDANEWM 265
Cdd:TIGR04056 159 DGVPRDNgLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGK-PKISYNAEFGFSTPTRLPEMLNAYEYA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 266 STFKQGLENANEFQGKNFTTDLsqiftDERLFNADGSPKY-NTNWQDEA-SRTAISHNHQISFQRTGEGSSIGAFINYTD 343
Cdd:TIGR04056 238 ELYNEALLNRGSSPPDIYTDEE-----IEAYRNGLDPDLYpNTDWQDEIfKRTAFNQRHNLSVSGGTEKARYYVSLGYYN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 344 QQGILLNSYFKRINAKLAYDDKPTDWLSTSVNLLVNHTWGNR---TSDNPYGQGALRTMIEQLPFLPVKLDGEYTQTNII 420
Cdd:TIGR04056 313 EEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNpggSTSNIWGALMLFPRGTPYSTPPVYSDGYYPAYNSG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 421 NTSSIlnnqtdpnsgkqgfspegvgNPVELLERMQAMQYRTQIFGNAALTFHLMKGLDLKTQFGIDYHNNRDANYTPFTP 500
Cdd:TIGR04056 393 NTSLQ--------------------NPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPY 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 501 RPMINQSSE-GAASANNSNSLYWQEETYLTYVKDINKHHINAMAGMSWQEYNYtkfeasdSKYIDDFYGYYNLGSGTNRP 579
Cdd:TIGR04056 453 YYNATGGANnGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKS-------SSYGGLLDDLPSLDAGTSDA 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 580 SVGNDYDKWAMNSYFLRLAYSYDNKYMATVTGRYDGSSKFGQNNKYAFFPSVGLGWMISNEDFLKD-NSLISKLKLHTSY 658
Cdd:TIGR04056 526 SVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKFMKKlKKWLSFLKLRASY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 659 GLTGNSEIGT---YKSLATVSQSNTIIGDALHVVS---YLDNMPNPDLKWEKTGQWDLGFELGLFNNRLNFDISYYYKYT 732
Cdd:TIGR04056 606 GIVGNDNIGDrypYLSLYNLGDGGYNFGTNNGTSVtgiTESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKT 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 733 SDLLLDRPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQTHDFQWTSTLNLGFNKNRVEKLDESasvdpvtgkrqitTD 812
Cdd:TIGR04056 686 KDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEG-------------AY 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 813 GFVGYDMLIREGEELSSFYGYkragIYDGIPSNWDPETMNIPSTIGEKVTYKK-----------REIIGN-GLPDWMGSF 880
Cdd:TIGR04056 753 LPVKYPYISKEGGPIGQIYGY----IADGLFKDDDSPKQTFGNVRPGDIKYKDvngdgkiddddRVPIGYsNTPDLTYGF 828
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 881 INTFNYKGFDLTLDFQFTWGVDVMQ--EYYHSTVARFLTNGIDRLYKEAWHPTlNPSGKEQAIRLNNFGQGANNQADDDW 958
Cdd:TIGR04056 829 GNSFSYKGFDLSALFQGSGGGDVFNdgRGFYPFNGGDWGNVLKIVADNRWTPE-NPNADYPRLSYGDSNNSNNYQASTRW 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 959 VCNGSYLRCNMIQLGYTFNPTLIKKIGLSSLRLYANVNNAFLITskDYNGYDPDNSSRLGdnkwganrqfFTYPRPRTFT 1038
Cdd:TIGR04056 908 LEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTFS--KYKGWDPELQGNDG----------GAYPLQRTFS 975
|
....*
gi 2796448491 1039 FGLNV 1043
Cdd:TIGR04056 976 FGVNL 980
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
106-798 |
1.23e-50 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 190.04 E-value: 1.23e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 106 LDEVVVVGYGT-MRKSDLTGSISTAKGKDMLKAQSFNALDGLKgKVAGVNIfsnTGQPGGESRVIIRGIStiNASASPLY 184
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSV---TSAGGGAGQISIRGFG--GGGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 185 VVDGVVMS-------NFELLNPNDIESIEVLKDASSAaIYGARGANGVIMVTTKRGNAGKGVHVSYDGslsigkmarkid 257
Cdd:COG1629 75 LVDGVPLNdpsggdgGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSASY------------ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 258 vmdanewmstfkqglenanefqgknfttdlsqiftderlfnadGSpkYNTnwqdeasrtaisHNHQISFQRTGEGSSIGA 337
Cdd:COG1629 142 -------------------------------------------GS--YGT------------YRASLSLSGGNGKLAYRL 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 338 FINYTDQQGILLNSYFKRINAKLAYDDKPTDWLSTSVNLlvnhtwgnrtsdnpygqgalrtmieqlpflpvkldgEYTQT 417
Cdd:COG1629 165 SASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSA------------------------------------SYSDS 208
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 418 NIINTSSILNNQTDPN-SGKQGFSPEGVGNpvellermqamQYRTQIFGNAALTF-HLMKGLDLKTQFGIDYH-NNRDAN 494
Cdd:COG1629 209 DQDSPGYLTLAALRPRgAMDDGTNPYSNDT-----------DDNTRDRYSLSLEYeHLGDGLKLSASAYYRYDdTDLDSD 277
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 495 YTPftprpmiNQSSEGAASANNSNSLYWQEETYLTYVKDINKHHiNAMAGMSWQEYNYtkfeasDSKYIDDFYGYYNLGS 574
Cdd:COG1629 278 FTP-------TPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKH-TLLVGLDYQRQDL------DGSGYPLDLGSGSLPT 343
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 575 GTNRPSVGNDYDkwaMNSYFLRLAYSYDNKYMATVTGRYDGSSKFGQN------------NKYAFFPSVGLGWMISNEdf 642
Cdd:COG1629 344 LTSGADDDGTTT---SLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDDtvtgtdsasgsrSYSAFSPSLGLTYQLSPN-- 418
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 643 lkdnsliskLKLHTSYGLTgnSEIGTYKSLATVSQSNTIIGdalhvvsyldnmpNPDLKWEKTGQWDLGFELGLFNNRLN 722
Cdd:COG1629 419 ---------LSLYASYSRG--FRAPTFGELYANGTDPYSVG-------------NPDLKPETSTNYELGLRYRLLDGRLS 474
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2796448491 723 FDISYYYKYTSDLLLDRPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQthdfQWTSTLNLGFNKNRVEKLDESA 798
Cdd:COG1629 475 LSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTDAKFDDDTDGS 546
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
29-111 |
1.67e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 84.18 E-value: 1.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 29 ISGTVTDDQGEAVISG-TVKVKNGSTGTITDINGKYTLSVPS--NATLVFSYIGYITQEFKV--SELKSNVLNVVLQSDT 103
Cdd:pfam13715 1 ISGTVVDENTGEPLPGaTVYVKGTTKGTVTDADGNFELKNLPagTYTLVVSFVGYKTQEKKVtvSNDNTLDVNFLLKEDA 80
|
....*...
gi 2796448491 104 KALDEVVV 111
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
125-818 |
5.11e-12 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 69.79 E-value: 5.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 125 SISTAKGKDMLKAQSFNALDGLKgKVAGVNIfsNTGQPGGESRVIIRGISTINAsaspLYVVDGV--------VMSNFEL 196
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLR-RIPGVSV--TRGGGGGGSTISIRGFGPDRT----LVLVDGLplassnygRGVDLNT 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 197 LNPNDIESIEVLKDASSaAIYGARGANGVIMVTTKRGNAGKGVHVSYDgslsigkmarkidvMDANEWMSTFkqglenan 276
Cdd:cd01347 74 IPPELIERVEVLKGPSS-ALYGSGAIGGVVNIITKRPTDEFGGSVTAG--------------YGSDNSGSSG-------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 277 efqGKNFttDLSQIFTDERLFNAdgspkyntnwqdeasRTAISHNHQISFQRTgegssiGAFINYTDQQGILlnsyfkrI 356
Cdd:cd01347 131 ---GGGF--DVSGALADDGAFGA---------------RLYGAYRDGDGTIDG------DGQADDSDEERYN-------V 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 357 NAKLAYDdkPTDwlSTSVNLLVNHTWGnrTSDNPYGQGALRTMIEQLPFLPvkldgeytqtniinTSSILNNQTDPNSGk 436
Cdd:cd01347 178 AGKLDWR--PDD--DTRLTLDAGYQDQ--DADGPGGTLPANGTGSSLGGGP--------------SSNTNGDRDWDYRD- 236
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 437 qgfspegvgnpvellERMQAMQYRTQIFGNAAltfhlmkGLDLKTQFGIDYHNNRDANYTPFTPRPMINQSSEGAASANN 516
Cdd:cd01347 237 ---------------RYRKRASLGLEHDLNDT-------GWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSE 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 517 SNSLYWQEETYLTYVKDINKHHINAMAGMSWQEYNYtkfeasdskyidDFYGYynlgsgtnrpsvgndydkwamnSYFLR 596
Cdd:cd01347 295 RDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREEL------------DEKQT----------------------ALYAQ 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 597 LAYSYDNKYMATVTGRYD---GSSKFGQNNKY-------AFFPSVGLGWmisnedflkdnSLISKLKLHTSY--GLTGNS 664
Cdd:cd01347 341 DTIELTDDLTLTLGLRYDhydQDSKDTIAGGTtakksysHWSPSLGLVY-----------KLTDGLSLYASYsqGFRAPS 409
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 665 eigTYKSLATVSQSNTIIGdalhvvsyldnmPNPDLKWEKTGQWDLGFElGLFNNRLNFDISYYYKYTSDLLLDRPVPES 744
Cdd:cd01347 410 ---LGELYGGGSHGGTAAV------------GNPNLKPEKSKQYELGLK-YDPGDGLTLSAALFRIDIKNEIVSTPTNTG 473
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796448491 745 TGYSSIMDNIGAVSNRGLDILVTAYPiqTHDFQWtsTLNLGFNKNRVEKLDESASVDPVTGKRQITTDGFVGYD 818
Cdd:cd01347 474 LGLVTVYVNGGKARIRGVELEASYDL--TDGLGL--TGSYTYTDTEVKRTDGATTGNRLPGIPKHTANLGLDYE 543
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
104-264 |
1.82e-03 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 42.32 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 104 KALDEVVVVGYGTMRK-SDLTGSISTAKGKDMLKAQSFNALDGLKGkVAGVNIFSNTGQPGGeSRVIIRGIstinASASP 182
Cdd:PRK13486 23 AAEDVMIVSASGYEKKlTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDVESGTGKTGG-LEISIRGM----PASYT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 183 LYVVDGVVMSNFELLNPND--------------IESIEVLKDASSaAIYGARGANGVIMVTTKRgNAGKgvhvsYDGSLS 248
Cdd:PRK13486 97 LILIDGVRQGGSSDVTPNGfsamntgfmpplaaIERIEVIRGPMS-TLYGSDAMGGVVNIITRK-NADK-----WLSSVN 169
|
170
....*....|....*.
gi 2796448491 249 IGkmarkIDVMDANEW 264
Cdd:PRK13486 170 AG-----LNLQESNKW 180
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| OMP_RagA_SusC |
TIGR04056 |
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ... |
27-1043 |
0e+00 |
|
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 274948 [Multi-domain] Cd Length: 981 Bit Score: 844.95 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 27 KSISGTVTDDQGEAVISGTVKVKNGSTGTITDINGKYTLSVPSNATLVFSYIGYITQEFKVSelKSNVLNVVLQSDTKAL 106
Cdd:TIGR04056 1 ITVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVFSYIGYKTQEVKVK--GQKNLNITLKEDTQEL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 107 DEVVVVGYGTMRKSDLTGSISTAKGKDMLKAQSFNALDGLKGKVAGVNIFSNTGQPGGESRVIIRGISTINASASPLYVV 186
Cdd:TIGR04056 79 DEVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 187 DGVVMSN-FELLNPNDIESIEVLKDASSAAIYGARGANGVIMVTTKRGNAGKgVHVSYDGSLSIGKMARKIDVMDANEWM 265
Cdd:TIGR04056 159 DGVPRDNgLSDLNPEDIESISVLKDASATAIYGSRGANGVILITTKRGKEGK-PKISYNAEFGFSTPTRLPEMLNAYEYA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 266 STFKQGLENANEFQGKNFTTDLsqiftDERLFNADGSPKY-NTNWQDEA-SRTAISHNHQISFQRTGEGSSIGAFINYTD 343
Cdd:TIGR04056 238 ELYNEALLNRGSSPPDIYTDEE-----IEAYRNGLDPDLYpNTDWQDEIfKRTAFNQRHNLSVSGGTEKARYYVSLGYYN 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 344 QQGILLNSYFKRINAKLAYDDKPTDWLSTSVNLLVNHTWGNR---TSDNPYGQGALRTMIEQLPFLPVKLDGEYTQTNII 420
Cdd:TIGR04056 313 EEGILKNSDYKRYNFRANIDAKLTKTLKLSLNVSGSLSKYNNpggSTSNIWGALMLFPRGTPYSTPPVYSDGYYPAYNSG 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 421 NTSSIlnnqtdpnsgkqgfspegvgNPVELLERMQAMQYRTQIFGNAALTFHLMKGLDLKTQFGIDYHNNRDANYTPFTP 500
Cdd:TIGR04056 393 NTSLQ--------------------NPYALLNRGYNENERNRLNGNASLEQKITKGLKLKGTFSYDYSNYKNKKYYKNPY 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 501 RPMINQSSE-GAASANNSNSLYWQEETYLTYVKDINKHHINAMAGMSWQEYNYtkfeasdSKYIDDFYGYYNLGSGTNRP 579
Cdd:TIGR04056 453 YYNATGGANnGYYSESNSRSRNYYLEATLNYNRTFGKHNVSALLGYSQQENKS-------SSYGGLLDDLPSLDAGTSDA 525
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 580 SVGNDYDKWAMNSYFLRLAYSYDNKYMATVTGRYDGSSKFGQNNKYAFFPSVGLGWMISNEDFLKD-NSLISKLKLHTSY 658
Cdd:TIGR04056 526 SVSGSDSEYRLQSLFGRATYSYKDRYLLEFNFRYDGSSRFAKGNRWGFFPSVSLGWRISEEKFMKKlKKWLSFLKLRASY 605
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 659 GLTGNSEIGT---YKSLATVSQSNTIIGDALHVVS---YLDNMPNPDLKWEKTGQWDLGFELGLFNNRLNFDISYYYKYT 732
Cdd:TIGR04056 606 GIVGNDNIGDrypYLSLYNLGDGGYNFGTNNGTSVtgiTESRYGNPNLKWEKTKKWNLGLDLGFFNNRLSLTVDYYYKKT 685
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 733 SDLLLDRPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQTHDFQWTSTLNLGFNKNRVEKLDESasvdpvtgkrqitTD 812
Cdd:TIGR04056 686 KDILQSRSLPSVTGYSSPYANIGKVKNKGVELSLNYRNKIGKDFSWSVRGNFTYNKNKILELDEG-------------AY 752
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 813 GFVGYDMLIREGEELSSFYGYkragIYDGIPSNWDPETMNIPSTIGEKVTYKK-----------REIIGN-GLPDWMGSF 880
Cdd:TIGR04056 753 LPVKYPYISKEGGPIGQIYGY----IADGLFKDDDSPKQTFGNVRPGDIKYKDvngdgkiddddRVPIGYsNTPDLTYGF 828
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 881 INTFNYKGFDLTLDFQFTWGVDVMQ--EYYHSTVARFLTNGIDRLYKEAWHPTlNPSGKEQAIRLNNFGQGANNQADDDW 958
Cdd:TIGR04056 829 GNSFSYKGFDLSALFQGSGGGDVFNdgRGFYPFNGGDWGNVLKIVADNRWTPE-NPNADYPRLSYGDSNNSNNYQASTRW 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 959 VCNGSYLRCNMIQLGYTFNPTLIKKIGLSSLRLYANVNNAFLITskDYNGYDPDNSSRLGdnkwganrqfFTYPRPRTFT 1038
Cdd:TIGR04056 908 LEDGSYLRLKNLTLGYTLPKKWLKKIGISNLRVYFSGQNLFTFS--KYKGWDPELQGNDG----------GAYPLQRTFS 975
|
....*
gi 2796448491 1039 FGLNV 1043
Cdd:TIGR04056 976 FGVNL 980
|
|
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
106-798 |
1.23e-50 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 190.04 E-value: 1.23e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 106 LDEVVVVGYGT-MRKSDLTGSISTAKGKDMLKAQSFNALDGLKgKVAGVNIfsnTGQPGGESRVIIRGIStiNASASPLY 184
Cdd:COG1629 1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSV---TSAGGGAGQISIRGFG--GGGNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 185 VVDGVVMS-------NFELLNPNDIESIEVLKDASSAaIYGARGANGVIMVTTKRGNAGKGVHVSYDGslsigkmarkid 257
Cdd:COG1629 75 LVDGVPLNdpsggdgGLSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSASY------------ 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 258 vmdanewmstfkqglenanefqgknfttdlsqiftderlfnadGSpkYNTnwqdeasrtaisHNHQISFQRTGEGSSIGA 337
Cdd:COG1629 142 -------------------------------------------GS--YGT------------YRASLSLSGGNGKLAYRL 164
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 338 FINYTDQQGILLNSYFKRINAKLAYDDKPTDWLSTSVNLlvnhtwgnrtsdnpygqgalrtmieqlpflpvkldgEYTQT 417
Cdd:COG1629 165 SASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSA------------------------------------SYSDS 208
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 418 NIINTSSILNNQTDPN-SGKQGFSPEGVGNpvellermqamQYRTQIFGNAALTF-HLMKGLDLKTQFGIDYH-NNRDAN 494
Cdd:COG1629 209 DQDSPGYLTLAALRPRgAMDDGTNPYSNDT-----------DDNTRDRYSLSLEYeHLGDGLKLSASAYYRYDdTDLDSD 277
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 495 YTPftprpmiNQSSEGAASANNSNSLYWQEETYLTYVKDINKHHiNAMAGMSWQEYNYtkfeasDSKYIDDFYGYYNLGS 574
Cdd:COG1629 278 FTP-------TPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKH-TLLVGLDYQRQDL------DGSGYPLDLGSGSLPT 343
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 575 GTNRPSVGNDYDkwaMNSYFLRLAYSYDNKYMATVTGRYDGSSKFGQN------------NKYAFFPSVGLGWMISNEdf 642
Cdd:COG1629 344 LTSGADDDGTTT---SLALYAQDTYKLTDKLTLTAGLRYDYVSYDVDDtvtgtdsasgsrSYSAFSPSLGLTYQLSPN-- 418
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 643 lkdnsliskLKLHTSYGLTgnSEIGTYKSLATVSQSNTIIGdalhvvsyldnmpNPDLKWEKTGQWDLGFELGLFNNRLN 722
Cdd:COG1629 419 ---------LSLYASYSRG--FRAPTFGELYANGTDPYSVG-------------NPDLKPETSTNYELGLRYRLLDGRLS 474
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2796448491 723 FDISYYYKYTSDLLLDRPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQthdfQWTSTLNLGFNKNRVEKLDESA 798
Cdd:COG1629 475 LSLALFYSDVDNEILSVPLPNDSGFSTYYTNAGKARSYGVELELSYQLTP----GLSLNASYSYTDAKFDDDTDGS 546
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
99-793 |
3.42e-37 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 149.24 E-value: 3.42e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 99 LQSDTKALDEVVVVGYGTMRK-SDLTGSISTAKGKDMLKAQSFNALDGLKgKVAGVNIFSNTGqPGGESRVIIRGIStin 177
Cdd:COG4771 20 LAEDATELEEVVVTATRTEQSlSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGG-RGGSSGISIRGLG--- 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 178 aSASPLYVVDGVVMSN--------FELLNPNDIESIEVLKDASSaAIYGARGANGVIMVTTKRGNAGKGVHVSYDGSlsi 249
Cdd:COG4771 95 -GDRVLVLIDGVPVNNpalggggdLSYIPPDDIERIEVIRGPAS-ALYGSDAIGGVINIITKKPTDELEGSVSLGYG--- 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 250 gkmarkidvmdanewmstfkqglenanefqgknfttdlsqiftderlfnadgspkyntnwqdeaSRTAISHNHQISFQRT 329
Cdd:COG4771 170 ----------------------------------------------------------------SNGNGTYSGSLSLGGP 185
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 330 GEGSSIGAFINYTDQQGIllnsyfkrINAKLAYDDKPTDWLSTSVNLLVNHTWGNRTSdnpygqgalrtmieqlpflpVK 409
Cdd:COG4771 186 GDKLSFLLSGSYRDRDGY--------LDYRNGGFVGNSGYERYNLNAKLGYRLSDNHR--------------------LS 237
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 410 LDGEYTQTNIINTSSILNNQTDPNSGkqgfspegvgnpvelLERMQAMQYRTQIFGNAALTFhlmkGLDLKTQFGIDYHN 489
Cdd:COG4771 238 LSGGYSRQDRDGGPPTLGDTEISSDN---------------AGDRDTTTDRGNYSLRYNGDL----GDNLDLSLYYSRTD 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 490 NRDANYTPFTPRPMINQSSEGAASANNSNSLYWQEETYLTYvkdinkhhinamaGMSWQeynytkfeasdskyiddfygY 569
Cdd:COG4771 299 RDSTNGSLGGSTGSFSDSDDTTYGLELDLTYPLGGNHTLTL-------------GAEYR--------------------Y 345
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 570 YNLGSGTNRPSVGNDYDKWAmnsYFLRLAYSYDNKYMATVTGRYDGSSKFGQNNKYAFFPSVGLGWMISNEdflkdnsli 649
Cdd:COG4771 346 DDLDSSSFLGGADASRDTYG---LFAQDEWKLTDKLTLTAGLRYDYYSTFGASNYTAFSPRLGLRYDLSDN--------- 413
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 650 skLKLHTSYGLTGNSeigtyKSLATVSQSNTIIGDALHVvsyldnmPNPDLKWEKTGQWDLGFELGLFNNRLNFDISYYY 729
Cdd:COG4771 414 --LTLRASYGRGFRA-----PSLAELYGSGTGTPGRYVL-------GNPDLKPETSDNYELGLEYRLGNGGLSLSLTGFY 479
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796448491 730 KYTSDLLLDRPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQthdfQWTSTLNLGFNKNRVEK 793
Cdd:COG4771 480 TDIKDLIVLVPVGPGPGDVLQYENVGKARTYGLELELKYRLGK----GLTLTASYTYLDSKIDD 539
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
109-345 |
1.20e-34 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 133.84 E-value: 1.20e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 109 VVVVGYG-TMRKSDLTGSISTAKGKDMLKAQSFNALDGLKgKVAGVNIfSNTGQPGGESRVIIRGIStinaSASPLYVVD 187
Cdd:COG4206 1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQV-SSSGGPGSAASISIRGLG----SNQTLVLID 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 188 GVVMSN-------FELLNPNDIESIEVLKDASSAaIYGARGANGVIMVTTKRGNAGKGVHVSY--------DGSLSIGKM 252
Cdd:COG4206 75 GVPLNDpslggvdLSLIPPDDIERIEVLKGAASA-LYGSDAIGGVINITTKKGKKGFKGSVSAsygsfgtrRLSASLSGG 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 253 ARKIDVMDANEWMST-----FKQGLENANEFQGKNFTTDLSQIFTDERLFNADGSPKYNTNWQDEASRTAISHNHQISFQ 327
Cdd:COG4206 154 AGKFSYSLSASYRRSdgyryNDPDLRNNDGYENTSLNARLGYKLGDNGSLSLSGGYSDSERGYPGAVGSDRNLRLSLSLE 233
|
250
....*....|....*...
gi 2796448491 328 RTGEGSSIGAFINYTDQQ 345
Cdd:COG4206 234 YKLSDGWSLLLLAYYYYD 251
|
|
| CarbopepD_reg_2 |
pfam13715 |
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ... |
29-111 |
1.67e-19 |
|
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.
Pssm-ID: 433425 [Multi-domain] Cd Length: 88 Bit Score: 84.18 E-value: 1.67e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 29 ISGTVTDDQGEAVISG-TVKVKNGSTGTITDINGKYTLSVPS--NATLVFSYIGYITQEFKV--SELKSNVLNVVLQSDT 103
Cdd:pfam13715 1 ISGTVVDENTGEPLPGaTVYVKGTTKGTVTDADGNFELKNLPagTYTLVVSFVGYKTQEKKVtvSNDNTLDVNFLLKEDA 80
|
....*...
gi 2796448491 104 KALDEVVV 111
Cdd:pfam13715 81 LLLDEVVV 88
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
118-225 |
8.36e-19 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 82.70 E-value: 8.36e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 118 RKSDLTGSISTAKGKDMLKAQSFNALDGLKGkVAGVNIFSNTGqpGGESRVIIRGIStinaSASPLYVVDGVVMSN---- 193
Cdd:pfam07715 1 DLRDTPGSVSVVTAEDIEDQGATNLADALRG-VPGVSVSSGGG--GGGSSISIRGFG----SNRVLVLVDGVPLNSgggg 73
|
90 100 110
....*....|....*....|....*....|....*
gi 2796448491 194 ---FELLNPNDIESIEVLKDASSaAIYGARGANGV 225
Cdd:pfam07715 74 svdLNSIDPEDIERVEVLKGPAS-ALYGSGAIGGV 107
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
415-770 |
2.33e-14 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 76.73 E-value: 2.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 415 TQTNIINTSSILNNQTDPNSGKQGFSPEGVGNPVELLERMQAMQYRTQIFGNAALTFHlmkGLDLKTQFGIDYHN--NRD 492
Cdd:pfam00593 8 LLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSL---GYDYDLGDGLSWLStlRLG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 493 ANYTPFTPRPMINQSSEGAASANNSNSLYWQEETYLTYVKDINKHHINAMAGMSWQE--YNYTKFEASDSKYIDDFYGYY 570
Cdd:pfam00593 85 LRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTagLDYRRLDDDAYDPYDPANPSS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 571 NLGSGTNRPSVGndydkwamnsYFLRLAYSYDNKYMATVTGRYDGSSKFGQNNKY----------AFFPSVGLGWMISNE 640
Cdd:pfam00593 165 SSYSDTTTDSYG----------LYLQDNIKLTDRLTLTLGLRYDHYSTDGDDGNGggdnfsrsysAFSPRLGLVYKPTDN 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 641 dflkdnsliskLKLHTSYGLTGNseigtykslatVSQSNTIIGDALHVVSYLDNMPNPDLKWEKTGQWDLGFElgLFNNR 720
Cdd:pfam00593 235 -----------LSLYASYSRGFR-----------APSLGELYGSGSGGGGGAVAGGNPDLKPETSDNYELGLK--YDDGR 290
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 2796448491 721 LNFDISYYYKYTSDLLLDRPVPES-TGYSSIMDNIGAVSNRGLDILVTAYP 770
Cdd:pfam00593 291 LSLSLALFYIDIKNLITSDPDGPGlGGTVYTYTNVGKARIRGVELELSGRL 341
|
|
| SusC_RagA_signa |
TIGR04057 |
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model ... |
201-231 |
4.20e-14 |
|
TonB-dependent outer membrane receptor, SusC/RagA subfamily, signature region; This model describes a 31-residue signature region of the SusC/RagA family of outer membrane proteins from the Bacteriodetes. While many TonB-dependent outer membrane receptors are associated with siderophore import, this family seems to include generalized nutrient receptors that may convey fairly large oligomers of protein or carbohydrate. This family occurs in high copy numbers in the most abundant species of the human gut microbiome.
Pssm-ID: 274949 [Multi-domain] Cd Length: 31 Bit Score: 66.83 E-value: 4.20e-14
10 20 30
....*....|....*....|....*....|.
gi 2796448491 201 DIESIEVLKDASSAAIYGARGANGVIMVTTK 231
Cdd:TIGR04057 1 DIESISVLKDASAAAIYGSRGANGVILITTK 31
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
125-818 |
5.11e-12 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 69.79 E-value: 5.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 125 SISTAKGKDMLKAQSFNALDGLKgKVAGVNIfsNTGQPGGESRVIIRGISTINAsaspLYVVDGV--------VMSNFEL 196
Cdd:cd01347 1 SVSVITAEDIEKQPATSLADLLR-RIPGVSV--TRGGGGGGSTISIRGFGPDRT----LVLVDGLplassnygRGVDLNT 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 197 LNPNDIESIEVLKDASSaAIYGARGANGVIMVTTKRGNAGKGVHVSYDgslsigkmarkidvMDANEWMSTFkqglenan 276
Cdd:cd01347 74 IPPELIERVEVLKGPSS-ALYGSGAIGGVVNIITKRPTDEFGGSVTAG--------------YGSDNSGSSG-------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 277 efqGKNFttDLSQIFTDERLFNAdgspkyntnwqdeasRTAISHNHQISFQRTgegssiGAFINYTDQQGILlnsyfkrI 356
Cdd:cd01347 131 ---GGGF--DVSGALADDGAFGA---------------RLYGAYRDGDGTIDG------DGQADDSDEERYN-------V 177
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 357 NAKLAYDdkPTDwlSTSVNLLVNHTWGnrTSDNPYGQGALRTMIEQLPFLPvkldgeytqtniinTSSILNNQTDPNSGk 436
Cdd:cd01347 178 AGKLDWR--PDD--DTRLTLDAGYQDQ--DADGPGGTLPANGTGSSLGGGP--------------SSNTNGDRDWDYRD- 236
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 437 qgfspegvgnpvellERMQAMQYRTQIFGNAAltfhlmkGLDLKTQFGIDYHNNRDANYTPFTPRPMINQSSEGAASANN 516
Cdd:cd01347 237 ---------------RYRKRASLGLEHDLNDT-------GWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYSSE 294
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 517 SNSLYWQEETYLTYVKDINKHHINAMAGMSWQEYNYtkfeasdskyidDFYGYynlgsgtnrpsvgndydkwamnSYFLR 596
Cdd:cd01347 295 RDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREEL------------DEKQT----------------------ALYAQ 340
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 597 LAYSYDNKYMATVTGRYD---GSSKFGQNNKY-------AFFPSVGLGWmisnedflkdnSLISKLKLHTSY--GLTGNS 664
Cdd:cd01347 341 DTIELTDDLTLTLGLRYDhydQDSKDTIAGGTtakksysHWSPSLGLVY-----------KLTDGLSLYASYsqGFRAPS 409
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 665 eigTYKSLATVSQSNTIIGdalhvvsyldnmPNPDLKWEKTGQWDLGFElGLFNNRLNFDISYYYKYTSDLLLDRPVPES 744
Cdd:cd01347 410 ---LGELYGGGSHGGTAAV------------GNPNLKPEKSKQYELGLK-YDPGDGLTLSAALFRIDIKNEIVSTPTNTG 473
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796448491 745 TGYSSIMDNIGAVSNRGLDILVTAYPiqTHDFQWtsTLNLGFNKNRVEKLDESASVDPVTGKRQITTDGFVGYD 818
Cdd:cd01347 474 LGLVTVYVNGGKARIRGVELEASYDL--TDGLGL--TGSYTYTDTEVKRTDGATTGNRLPGIPKHTANLGLDYE 543
|
|
| CarboxypepD_reg |
pfam13620 |
Carboxypeptidase regulatory-like domain; |
28-99 |
1.26e-10 |
|
Carboxypeptidase regulatory-like domain;
Pssm-ID: 433354 [Multi-domain] Cd Length: 81 Bit Score: 58.45 E-value: 1.26e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 28 SISGTVTDDQGEAVISGTVKVKNGSTG----TITDINGKYTLS--VPSNATLVFSYIGYITQEFK---VSELKSNVLNVV 98
Cdd:pfam13620 1 TISGTVTDPSGAPVPGATVTVTNTDTGtvrtTTTDADGRYRFPglPPGTYTVTVSAPGFKTATRTgvtVTAGQTTTLDVT 80
|
.
gi 2796448491 99 L 99
Cdd:pfam13620 81 L 81
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
100-1045 |
1.13e-08 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 59.17 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 100 QSDTKALDEVVVVGYGTMRKS--DLTGSISTAKGKDMLKAQSFNALDGLKgKVAGVNIFSNTGqPGGESRVIIRGiSTIN 177
Cdd:COG4772 17 AEAATTLETVVVTGSRAAEARlkDVPGSVSVVDREELENQAATSLREVLR-RVPGVNVQEEDG-FGLRPNIGIRG-LGPR 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 178 ASASPLYVVDGVVMSNFELLNP--------NDIESIEVLKDASSAAiYGARGANGVIMVTTKRGNAGKGVHVS------- 242
Cdd:COG4772 94 RSRGITLLEDGIPIAPAPYGDPaayyfpdlERMERIEVLRGAAALR-YGPQTVGGAINFVTRTIPTAFGGELRvtggsfg 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 243 -YDGSLSIGKMARKIDVMdanewmstfkqglenaneFQGKNFTTDLSQIFTDERLFNadgspkYNTNWQdeasrtaishn 321
Cdd:COG4772 173 yRRTHASVGGTVGNFGYL------------------VEYSRKRGDGFRDNSGFDIND------FNAKLG----------- 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 322 hqisfQRTGEGSSIGAFINYTDQQ-----GILLNSYfkRINAKLAYddKPTDWLS---TSVNLLVNHTWGNRTSdnpygq 393
Cdd:COG4772 218 -----YRLSDRQELTLKFQYYDEDantpgGLTDAQF--DADPRQSY--RPADQFDtrrTQLSLRYEHQLSDNTT------ 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 394 gaLRTMieqlpflpvkldGEYTQTNIinTSSILNNQTDPNSGKQGFspegvgnpvelleRMQAMQYRTQ-IFGNAALTFH 472
Cdd:COG4772 283 --LTTT------------AYYNDFSR--NWYIRQNTADPNTPGLGL-------------RGNPRGYRSYgIEPRLTHRFE 333
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 473 LmKGLDLKTQFGIDYHNNRDANytpFTPRPMINQSSEGAASANN------SNSLYWQEETYLTyvkdinkHHINAMAGMs 546
Cdd:COG4772 334 L-GGVPHTLEVGLRYHREEEDR---KQYVNTYGQGRSGAGLRRDrrfsadALAAYAQNRFELT-------GRLTLTPGL- 401
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 547 wqeynytKFEASDSKYIDdfygYYNLGSGTNRpSVGNDYDKWAmnsyflrlaysydnkymatvtgrydgsskfgqnnkya 626
Cdd:COG4772 402 -------RYEHIRRDRTD----RYSTRTGGDD-SGSNSYSEFL------------------------------------- 432
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 627 ffPSVGLGWMISNEdflkdnslisklklHTSYGltgnseiGTYKSLATVSQSNTIIGDAlhvvsyldnmPNPDLKWEKTG 706
Cdd:COG4772 433 --PGLGLLYQLTDN--------------LQLYA-------NVSRGFEPPTFGDLAYGNG----------GNPDLKPEKSW 479
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 707 QWDLGFElGLFNNRLNFDISYYYKYTSDLLLdrPVPESTGYSSIMDNIGAVSNRGLDILVTAYPIQTHDFQWTSTLNLGF 786
Cdd:COG4772 480 NYELGTR-GRIGNGLSAEVALFYIDYDNELG--SCSAAGGDRSTFTNAGETRHQGLELALDYDLLKGGGLGLPLFAAYTY 556
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 787 NKNRVEKldesaSVDPVT-GKRqittdgfvgydmliregeelssfygykragiydgIPsnwdpetmnipstigekvtykk 865
Cdd:COG4772 557 TDAEFTS-----DFGPVFaGNR----------------------------------LP---------------------- 575
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 866 reiignGLPDWMGSFINTFNYKGFDLTLDFQFtwgvdvMQEYYHSTvarfltngidrlykeawhptlnpsgkeqairLNN 945
Cdd:COG4772 576 ------YVPRHQLTAGLGYEHGGWTANLNGRY------VSEQFTDA-------------------------------ANT 612
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 946 FGQGANNQADDDWVCNgsylrcnmIQLGYTFNPtlikkiglsSLRLYANVNNaflITSKDYNGydpdnsSRLGDNKWGAn 1025
Cdd:COG4772 613 VADGSFGKIPSYTVLD--------LSASYDFGK---------NLSLFAGVNN---LFDKRYIA------SRAPNYAAGI- 665
|
970 980
....*....|....*....|.
gi 2796448491 1026 rqfftYP-RPRTFTFGLNVAF 1045
Cdd:COG4772 666 -----RPgPPRTVYAGLRLKF 681
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
150-807 |
1.55e-07 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 55.27 E-value: 1.55e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 150 VAGVNIfsNTGQPGGESRVIIRGISTINAsasplYVVDGVVMSNFELLNPNDIESIEVLKDASSaAIYGARGANGVIMVT 229
Cdd:COG4774 36 VPGVTF--GAGEGGNGDSFSIRGFSASGD-----IYVDGLRDPGQYRRDTFNLERVEVLKGPAS-VLYGRGSPGGVINLV 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 230 TKRGNAGKgvhvSYDGSLSIGkmarkidvmdanewmstfkqglenanEFQGKNFTTDLSQIFTDE---RLfnadgspkyN 306
Cdd:COG4774 108 TKRPTDEP----FTEVTLTYG--------------------------SDGQRRATLDVNGPLGDDlayRL---------N 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 307 TNWQDEasrtaishnhqisfqrtgegssiGAFINYTDQqgillnsyfKRINAKLAYDDKPTDwlSTSVNLLVNHTWGNRT 386
Cdd:COG4774 149 GMYRDS-----------------------DSYRDGVDN---------DRWGIAPSLTWRLGD--RTRLTLDYEYQDDDRT 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 387 SDnpYGqgalrtmieqLPFL----PVKLDGEytqtniintssilNNQTDPNSGkqgfspegvgnpvellermqamQYRTQ 462
Cdd:COG4774 195 PD--YG----------VPAVangrPVDVDRS-------------TFYGQPDDY----------------------SDSET 227
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 463 IFGNAALTFHLMKGLDLKTQFGIdYHNNRDANYTPFTprpminqSSEGAASANNSNSLYWQEETYLTYVKDIN------- 535
Cdd:COG4774 228 DSATLRLEHDFNDNWTLRNALRY-SDYDRDYRNTYPT-------GGNATGTVTRSAYRRDQDNDTLSNQTDLTgkfdtgg 299
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 536 -KHHINAMAGMSWQEYNYTKFEASDSKYIDDFY--GYYNLGSGTNRPSVGNDYDKWAMnSYFLRLAYSYDNKYMATVTGR 612
Cdd:COG4774 300 vKHTLLAGVEYSREDSDNARYSGGGTAPTVNLYnpVYGAPVTGPTLGGADNDSRTDTT-GLYLQDTISLTDRWSLLAGLR 378
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 613 YD-----------GSSKFGQNNKyAFFPSVGLGWMISNEdflkdnsliskLKLHTSYGltgnseigtyKSLATVSQSNTI 681
Cdd:COG4774 379 YDrfdtdytdrttGATTSSYDDS-AFSPRAGLVYKPTPN-----------LSLYASYS----------TSFNPGGGAPSL 436
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 682 igdalhvvsyldNMPNPDLKWEKTGQWDLGFELGLFNNRLNFDISYYYkytsdllLDRP-----VPESTGYSSimdNIGA 756
Cdd:COG4774 437 ------------SNAGQALDPEKSRQYEVGVKWDLLDGRLSLTAALFR-------IEKTnvrttDPANPGVYV---QTGE 494
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|.
gi 2796448491 757 VSNRGLDILVTAYPIQthdfQWTSTLNLGFNKNRVeklDESASVDPVtGKR 807
Cdd:COG4774 495 QRSRGVELEATGELTP----GWSVLAGYTYLDAEI---TKSANAANV-GNR 537
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
100-232 |
5.13e-07 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 53.75 E-value: 5.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 100 QSDTKALDEVVVVGYGTMRKSDLTGSISTA-KG---------------KDMLKAQSFNALDGLKGKVAGVNIFSNTGqpG 163
Cdd:COG4773 26 AAEATTLPEVTVTGTAEGTGGYTAKSSSTAtKLdtplretpqsvsvvtRQLIEDQGATTLDDALRNVPGVTVSSYDG--G 103
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2796448491 164 GESRVIIRGISTINasasplYVVDGVVMSNFELLNPN--DIESIEVLKDASSaAIYGARGANGVIMVTTKR 232
Cdd:COG4773 104 GRDSFSIRGFSIDN------YLRDGLPLGGFGGGQPDtaNLERVEVLKGPAG-LLYGAGSPGGLVNLVTKR 167
|
|
| PRK13486 |
PRK13486 |
TonB-dependent receptor; |
104-264 |
1.82e-03 |
|
TonB-dependent receptor;
Pssm-ID: 139606 [Multi-domain] Cd Length: 696 Bit Score: 42.32 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 104 KALDEVVVVGYGTMRK-SDLTGSISTAKGKDMLKAQSFNALDGLKGkVAGVNIFSNTGQPGGeSRVIIRGIstinASASP 182
Cdd:PRK13486 23 AAEDVMIVSASGYEKKlTNAAASVSVISQEELQSSQYHDLAEALRS-VEGVDVESGTGKTGG-LEISIRGM----PASYT 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796448491 183 LYVVDGVVMSNFELLNPND--------------IESIEVLKDASSaAIYGARGANGVIMVTTKRgNAGKgvhvsYDGSLS 248
Cdd:PRK13486 97 LILIDGVRQGGSSDVTPNGfsamntgfmpplaaIERIEVIRGPMS-TLYGSDAMGGVVNIITRK-NADK-----WLSSVN 169
|
170
....*....|....*.
gi 2796448491 249 IGkmarkIDVMDANEW 264
Cdd:PRK13486 170 AG-----LNLQESNKW 180
|
|
|