|
Name |
Accession |
Description |
Interval |
E-value |
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
631-863 |
1.04e-74 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 244.05 E-value: 1.04e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 631 ALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDLDAFSPEEVKQFVETININCTLLLALINDILDLSRIE 710
Cdd:COG2205 1 ELEEALEELEELERLKSEFLANVSHELRTPLTSILGAAELLLDEEDLSPEERRELLEIIRESAERLLRLIEDLLDLSRLE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 711 SGTMDFKFGAFNLAFIMQEVHESQRLSMP-RDVELRIEIPEgEDKLVITDSVRLKQVVNNLINNAKKFTVTGS-ITFgYV 788
Cdd:COG2205 81 SGKLSLELEPVDLAELLEEAVEELRPLAEeKGIRLELDLPP-ELPLVYADPELLEQVLANLLDNAIKYSPPGGtITI-SA 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796428172 789 TNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSF--TQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG2205 159 RREGDGVRISVSDNGPGIPEEELERIFERFYRGDNSrgEGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
537-863 |
1.28e-71 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 239.04 E-value: 1.28e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 537 LRRFGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEINSRMSFRLKSVDGSYEWWEFRSTAYDSLTVDTPYMVL 616
Cdd:COG0642 1 LLLLLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 617 GVCQSIQRYKDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDLdafSPEEVKQFVETININCTLL 696
Cdd:COG0642 81 LLLLLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEE---LDEEQREYLETILRSADRL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 697 LALINDILDLSRIESGTMDFKFGAFNLAFIMQEVHESQRLSMP-RDVELRIEIPEGEDkLVITDSVRLKQVVNNLINNAK 775
Cdd:COG0642 158 LRLINDLLDLSRLEAGKLELEPEPVDLAELLEEVVELFRPLAEeKGIELELDLPDDLP-TVRGDPDRLRQVLLNLLSNAI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 776 KFTVTGS-ITFGyVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEDSFTQGAGLGLSICQTIVDRLHGSISVSSEL 852
Cdd:COG0642 237 KYTPEGGtVTVS-VRREGDRVRISVEDTGPGIPPEDLERIFEPFFrtDPSRRGGGTGLGLAIVKRIVELHGGTIEVESEP 315
|
330
....*....|.
gi 2796428172 853 GKGTRFEVVIP 863
Cdd:COG0642 316 GKGTTFTVTLP 326
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
504-867 |
2.03e-68 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 232.52 E-value: 2.03e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 504 MQRRFFNMAVEESSIYPWQYNMRMNRFHFPGGLLRRFGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEINSRM 583
Cdd:COG5002 23 LLLLLLLLLLLLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALL 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 584 SFRLKSVDGSYEWWEFRSTAYDSLTVDTPYMVLGVCQSIQRYKDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNA 663
Cdd:COG5002 103 ILLLLLALLILLAALLLLLSELLLLLLLLGRLSLRLSALLLGLLLLAAVERDITELERLEQMRREFVANVSHELRTPLTS 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 664 IVGFSDLLKDLDAFSPEEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNLAFIMQEVHESQRLSMP-RDV 742
Cdd:COG5002 183 IRGYLELLLDGAADDPEERREYLEIILEEAERLSRLVNDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLAEeKGI 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 743 ELRIEIPEgEDKLVITDSVRLKQVVNNLINNAKKFTVTGS-ITFGyVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKE 821
Cdd:COG5002 263 ELELDLPE-DPLLVLGDPDRLEQVLTNLLDNAIKYTPEGGtITVS-LREEDDQVRISVRDTGIGIPEEDLPRIFERFYRV 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 2796428172 822 DS----FTQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIPDANE 867
Cdd:COG5002 341 DKsrsrETGGTGLGLAIVKHIVEAHGGRIWVESEPGKGTTFTITLPLARE 390
|
|
| TMAO_torS |
TIGR02956 |
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the ... |
599-863 |
2.37e-52 |
|
TMAO reductase sytem sensor TorS; This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems]
Pssm-ID: 274362 [Multi-domain] Cd Length: 968 Bit Score: 198.08 E-value: 2.37e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 599 FRSTAYDSLTVDtpYMVLGVCQSIQRYKDTEEALIA----------------------ARDRALQADKLKSAFLANMSHE 656
Cdd:TIGR02956 397 FRDTAAHNLKLQ--ADERQVAQELQEHKESLEQLVAqrtqelaetnerlnaevknhakARAEAEEANRAKSAFLATMSHE 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 657 IRTPLNAIVGFSDLLKDLDAfsPEEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNLAFIMQEVHE-SQR 735
Cdd:TIGR02956 475 IRTPLNGILGTLELLGDTGL--TSQQQQYLQVINRSGESLLDILNDILDYSKIEAGHLSISPRPFDLNALLDDVHHlMVS 552
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 736 LSMPRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIF 815
Cdd:TIGR02956 553 RAQLKGIQLRLNIPEQLPNWWQGDGPRIRQVLINLVGNAIKFTDRGSVVLRVSLNDDSSLLFEVEDTGCGIAEEEQATLF 632
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2796428172 816 erfykeDSFTQ--------GAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:TIGR02956 633 ------DAFTQadgrrrsgGTGLGLAISQRLVEAMDGELGVESELGVGSCFWFTLP 682
|
|
| KinE |
COG5809 |
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome ... |
367-863 |
8.65e-49 |
|
Sporulation sensor histidine kinase E [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444511 [Multi-domain] Cd Length: 489 Bit Score: 180.56 E-value: 8.65e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 367 RLLIQHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGlssetYTSRFYEGQMAGSIfrIYMNGENILQDL 446
Cdd:COG5809 3 SSKMELQLRKSEQRFRSLFENAPDAILILDLEGKILKVNPAAERIFG-----YTEDELLGTNILDF--LHPDDEKELREI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 447 LKKVRTGKSPIpipEKAFMQENHQGTYFPVSGEVVPIF-ANEKMTGMAIVCRNISE-----------EEMQRRFFNMAVE 514
Cdd:COG5809 76 LKLLKEGESRD---ELEFELRHKNGKRLEFSSKLSPIFdQNGDIEGMLAISRDITErkrmeealresEEKFRLIFNHSPD 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 515 ESSIYPWQYNMR-MNRFHfpgglLRRFGYiGDTDLLTRdEMDALIHPEDLPHTRRNFDAILLGNEInSRMSFRLKSVDGS 593
Cdd:COG5809 153 GIIVTDLDGRIIyANPAA-----CKLLGI-SIEELIGK-SILELIHSDDQENVAAFISQLLKDGGI-AQGEVRFWTKDGR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 594 YEWWEFRSTAYDSLtvDTPYMVLGVCQSIQRYKDTEEALiaardraLQADKLKSA--FLANMSHEIRTPLNAIVGFSDLL 671
Cdd:COG5809 225 WRLLEASGAPIKKN--GEVDGIVIIFRDITERKKLEELL-------RKSEKLSVVgeLAAGIAHEIRNPLTSLKGFIQLL 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 672 KDLDAfspEEVKQFVETI-----NINctlllALINDILDLSRIESGtmdfKFGAFNLAFIMQEV---HESQRLSmpRDVE 743
Cdd:COG5809 296 KDTID---EEQKTYLDIMlseldRIE-----SIISEFLVLAKPQAI----KYEPKDLNTLIEEViplLQPQALL--KNVQ 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 744 LRIEIPEGEDkLVITDSVRLKQVVNNLINNAKKFTVTGsitfGYVTNREGYT-----TIFVEDTGSGISEDAQKHIFERF 818
Cdd:COG5809 362 IELELEDDIP-DILGDENQLKQVFINLLKNAIEAMPEG----GNITIETKAEdddkvVISVTDEGCGIPEERLKKLGEPF 436
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 2796428172 819 Y--KEdsftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG5809 437 YttKE----KGTGLGLMVSYKIIEEHGGKITVESEVGKGTTFSITLP 479
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
365-867 |
2.47e-47 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 176.51 E-value: 2.47e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 365 QTRLLIQHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSETYTSRFYEGQMAGSIFRIYMNGENILQ 444
Cdd:COG4251 1 LLLLALLLLLLLLLLLLLLLLLLLLLVLLLALALLLLLALLVLLLLLIRLLLLLLLSLLALLLLLLLLLLLLLVLAALAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 445 DLLKKVRTGKSPIPIPEKAFMQENHQGTYFPVSGEVVPIFANEKMTGMAIVCRNISEEEMQRRFFNMAVEESSIYPWQYN 524
Cdd:COG4251 81 LLLLLLLELALVLLALLLVLLLLLALLLLLALLLLLELLLLLLALLLLLLLLALLLLEELALLRLALALLLLLLLLLLLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 525 MRMNRFHFPGGLLRRFGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEINSRMSFRLKSVDGSYEWWEFRSTAY 604
Cdd:COG4251 161 LLLLALILALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 605 DSLTVDTPYMVLGVCQSIQRYKDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLK-DLDAFSPEEVK 683
Cdd:COG4251 241 LILLLLLLILVLELLELRLELEELEEELEERTAELERSNEELEQFAYVASHDLREPLRKISGFSQLLEeDYGDKLDEEGR 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 684 QFVETININCTLLLALINDILDLSRIESGTMDFKfgAFNLAFIMQEVHESQRLSMP-RDVELRIE-IPEgedklVITDSV 761
Cdd:COG4251 321 EYLERIRDAAERMQALIDDLLAYSRVGRQELEFE--PVDLNELLEEVLEDLEPRIEeRGAEIEVGpLPT-----VRGDPT 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 762 RLKQVVNNLINNAKKFT---VTGSITFGYvTNREGYTTIFVEDTGSGISEDAQKHIFERFYK---EDSFtQGAGLGLSIC 835
Cdd:COG4251 394 LLRQVFQNLISNAIKYSrpgEPPRIEIGA-EREGGEWVFSVRDNGIGIDPEYAEKIFEIFQRlhsRDEY-EGTGIGLAIV 471
|
490 500 510
....*....|....*....|....*....|..
gi 2796428172 836 QTIVDRLHGSISVSSELGKGTRFEVVIPDANE 867
Cdd:COG4251 472 KKIVERHGGRIWVESEPGEGATFYFTLPKAPA 503
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
518-863 |
1.87e-46 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 170.36 E-value: 1.87e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 518 IYPWQYNMRMNRFHFPGGLLRRFGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEINSRMSFRLKSVDGSYEWW 597
Cdd:COG4191 12 LALLRALALALALLLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 598 EFRSTAYDSLTVDTPYMVLGVCQSIQRYKDTEEALIAARDRALQADKLKS--AFLANMSHEIRTPLNAIVGFSDLLKDL- 674
Cdd:COG4191 92 ALLLLLLAALDAEENAELEELERDITELERAEEELRELQEQLVQSEKLAAlgELAAGIAHEINNPLAAILGNAELLRRRl 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 675 -DAFSPEEVKQFVETININCTLLLALINDILDLSRIESGTMDfkfgAFNLAFIMQEVHESQRLSMP-RDVELRIEIPEgE 752
Cdd:COG4191 172 eDEPDPEELREALERILEGAERAAEIVRSLRAFSRRDEEERE----PVDLNELIDEALELLRPRLKaRGIEVELDLPP-D 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 753 DKLVITDSVRLKQVVNNLINNAK---KFTVTGSITFGyVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEDSftQG 827
Cdd:COG4191 247 LPPVLGDPGQLEQVLLNLLINAIdamEEGEGGRITIS-TRREGDYVVISVRDNGPGIPPEVLERIFEPFFttKPVG--KG 323
|
330 340 350
....*....|....*....|....*....|....*.
gi 2796428172 828 AGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG4191 324 TGLGLSISYGIVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
603-863 |
9.07e-43 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 168.28 E-value: 9.07e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 603 AYDSL--TVDTPYMVLGvcqsiQRYKDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDldafSPE 680
Cdd:PRK15347 358 AYNQLldTLNEQYDTLE-----NKVAERTQALAEAKQRAEQANKRKSEHLTTISHEIRTPLNGVLGALELLQN----TPL 428
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 681 EVKQF--VETINiNCTL-LLALINDILDLSRIESGTMDFKFGAFNLAFI----MQEVHeSQRLSmpRDVELRI----EIP 749
Cdd:PRK15347 429 TAEQMdlADTAR-QCTLsLLAIINNLLDFSRIESGQMTLSLEETALLPLldqaMLTIQ-GPAQS--KSLTLRTfvgaHVP 504
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 750 EgedKLViTDSVRLKQVVNNLINNAKKFTVTGSITFgYVTnREGYTTIF-VEDTGSGISEDAQKHIFERFYKEDSFTQGA 828
Cdd:PRK15347 505 L---YLH-LDSLRLRQILVNLLGNAVKFTETGGIRL-RVK-RHEQQLCFtVEDTGCGIDIQQQQQIFTPFYQADTHSQGT 578
|
250 260 270
....*....|....*....|....*....|....*
gi 2796428172 829 GLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK15347 579 GLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
558-863 |
8.56e-41 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 153.85 E-value: 8.56e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 558 IHPEDLPHTRRNFDAILLGNEINSRmSFRLKSVDGSYEWWEFRSTAYDSltVDTPYMVLGVCQSIQRYKDTEEALIaard 637
Cdd:COG3852 55 LFPEDSPLRELLERALAEGQPVTER-EVTLRRKDGEERPVDVSVSPLRD--AEGEGGVLLVLRDITERKRLERELR---- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 638 ralQADKLKSA--FLANMSHEIRTPLNAIVGFSDLLKDldAFSPEEVKQFVETININCTLLLALINDILDLSRiesgTMD 715
Cdd:COG3852 128 ---RAEKLAAVgeLAAGLAHEIRNPLTGIRGAAQLLER--ELPDDELREYTQLIIEEADRLNNLVDRLLSFSR----PRP 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 716 FKFGAFNLAFIMQEVHESQRLSMPRDVELRIE----IPEgedklVITDSVRLKQVVNNLINNAK-------KFTVTGSIT 784
Cdd:COG3852 199 PEREPVNLHEVLERVLELLRAEAPKNIRIVRDydpsLPE-----VLGDPDQLIQVLLNLVRNAAeampeggTITIRTRVE 273
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 785 FGYV---TNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEdsftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFE 859
Cdd:COG3852 274 RQVTlggLRPRLYVRIEVIDNGPGIPEEILDRIFEPFFttKE----KGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFR 349
|
....
gi 2796428172 860 VVIP 863
Cdd:COG3852 350 IYLP 353
|
|
| PRK10841 |
PRK10841 |
two-component system sensor histidine kinase RcsC; |
629-863 |
8.20e-40 |
|
two-component system sensor histidine kinase RcsC;
Pssm-ID: 182772 [Multi-domain] Cd Length: 924 Bit Score: 158.98 E-value: 8.20e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 629 EEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLL--KDLdafsPEEVKQFVETININCTLLLALINDILDL 706
Cdd:PRK10841 430 EESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLqtKEL----PKGVDRLVTAMNNSSSLLLKIISDILDF 505
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 707 SRIESGTMDFKFGAFNLAFIMQEVhESQRLSM--PRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAKKFTVTGSIT 784
Cdd:PRK10841 506 SKIESEQLKIEPREFSPREVINHI-TANYLPLvvKKRLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIV 584
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 785 FgYVTNREGYTTIFVEDTGSGISEDAQKHIFERFY-----KEDSFtQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFE 859
Cdd:PRK10841 585 L-HVRVDGDYLSFRVRDTGVGIPAKEVVRLFDPFFqvgtgVQRNF-QGTGLGLAICEKLINMMDGDISVDSEPGMGSQFT 662
|
....
gi 2796428172 860 VVIP 863
Cdd:PRK10841 663 IRIP 666
|
|
| PRK11091 |
PRK11091 |
aerobic respiration control sensor protein ArcB; Provisional |
616-863 |
3.00e-39 |
|
aerobic respiration control sensor protein ArcB; Provisional
Pssm-ID: 236842 [Multi-domain] Cd Length: 779 Bit Score: 156.64 E-value: 3.00e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 616 LGVCQSIQRYKDTEEAL-IAARDralqadklKSAFLANMSHEIRTPLNAIVGFSDLLKDLDaFSPEEVKQfVETININCT 694
Cdd:PRK11091 260 MGFGRDITERKRYQDALeKASRD--------KTTFISTISHELRTPLNGIVGLSRILLDTE-LTAEQRKY-LKTIHVSAI 329
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 695 LLLALINDILDLSRIE-------SGTMDFKfgAF-----NLAFIMQEvhesqrlsmPRDVELRIEIPEGEDKLVITDSVR 762
Cdd:PRK11091 330 TLGNIFNDIIDMDKMErrklqldNQPIDFT--DFladleNLSGLQAE---------QKGLRFDLEPLLPLPHKVITDGTR 398
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYK-EDS----FTQGAGLGLSICQT 837
Cdd:PRK11091 399 LRQILWNLISNAVKFTQQGGVTVRVRYEEGDMLTFEVEDSGIGIPEDELDKIFAMYYQvKDShggkPATGTGIGLAVSKR 478
|
250 260
....*....|....*....|....*.
gi 2796428172 838 IVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK11091 479 LAQAMGGDITVTSEEGKGSCFTLTIH 504
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
629-862 |
1.62e-38 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 146.58 E-value: 1.62e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 629 EEALIAARD--RALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDLDAFSPEEVKQFVETININCTLLLALINDILDL 706
Cdd:TIGR02966 95 EQKLLVARDvtRLRRLEQMRRDFVANVSHELRTPLTVLRGYLETLADGPDEDPEEWNRALEIMLEQSQRMQSLVEDLLTL 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 707 SRIESGTMDFKFGAFNLAFIMQEV-HESQRLSMPRDVELRIEIPEGEDklVITDSVRLKQVVNNLINNAKKFT-VTGSIT 784
Cdd:TIGR02966 175 SRLESAASPLEDEPVDMPALLDHLrDEAEALSQGKNHQITFEIDGGVD--VLGDEDELRSAFSNLVSNAIKYTpEGGTIT 252
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 785 FGYVTnREGYTTIFVEDTGSGIsedAQKHI---FERFYKEDSF----TQGAGLGLSICQTIVDRLHGSISVSSELGKGTR 857
Cdd:TIGR02966 253 VRWRR-DGGGAEFSVTDTGIGI---APEHLprlTERFYRVDKSrsrdTGGTGLGLAIVKHVLSRHHARLEIESELGKGST 328
|
....*
gi 2796428172 858 FEVVI 862
Cdd:TIGR02966 329 FSFIF 333
|
|
| PRK11107 |
PRK11107 |
hybrid sensory histidine kinase BarA; Provisional |
635-863 |
2.10e-38 |
|
hybrid sensory histidine kinase BarA; Provisional
Pssm-ID: 236848 [Multi-domain] Cd Length: 919 Bit Score: 154.62 E-value: 2.10e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 635 ARDRALQADKLKSAFLANMSHEIRTPLNAIVGFS-DLLKdldafSPEEVKQ--FVETININCTLLLALINDILDLSRIES 711
Cdd:PRK11107 282 AKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTrQTLK-----TPLTPTQrdYLQTIERSANNLLAIINDILDFSKLEA 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 712 GTMDFKFGAFNLAFIMQEV--------HEsqrlsmpRDVELRI----EIPEGedklVITDSVRLKQVVNNLINNAKKFTV 779
Cdd:PRK11107 357 GKLVLENIPFSLRETLDEVvtllahsaHE-------KGLELTLnidpDVPDN----VIGDPLRLQQIITNLVGNAIKFTE 425
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 780 TGSITF--GYVTNREGYTTIFVE--DTGSGISEDAQKHIFERFYKEDSFTQ----GAGLGLSICQTIVDRLHGSISVSSE 851
Cdd:PRK11107 426 SGNIDIlvELRALSNTKVQLEVQirDTGIGISERQQSQLFQAFRQADASISrrhgGTGLGLVITQKLVNEMGGDISFHSQ 505
|
250
....*....|..
gi 2796428172 852 LGKGTRFEVVIP 863
Cdd:PRK11107 506 PNRGSTFWFHLP 517
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
628-863 |
6.02e-37 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 144.33 E-value: 6.02e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 628 TEEALIAARD--RALQADKLKSA--FLANMSHEIRTPLNAIVGFSDLLK----DLDAFSPEEVKQFVETININCTLLLAL 699
Cdd:COG5000 179 DDGYVIVFDDitELLRAERLAAWgeLARRIAHEIKNPLTPIQLSAERLRrklaDKLEEDREDLERALDTIIRQVDRLKRI 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 700 INDILDLSRIESGtmdfKFGAFNLAFIMQEVHESQRLSMPR-DVELRIEIPEgEDKLVITDSVRLKQVVNNLINNA---- 774
Cdd:COG5000 259 VDEFLDFARLPEP----QLEPVDLNELLREVLALYEPALKEkDIRLELDLDP-DLPEVLADRDQLEQVLINLLKNAieai 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 775 KKftvTGSITFgYVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEdsftQGAGLGLSICQTIVDRLHGSISVSSEL 852
Cdd:COG5000 334 EE---GGEIEV-STRREDGRVRIEVSDNGPGIPEEVLERIFEPFFttKP----KGTGLGLAIVKKIVEEHGGTIELESRP 405
|
250
....*....|.
gi 2796428172 853 GKGTRFEVVIP 863
Cdd:COG5000 406 GGGTTFTIRLP 416
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
635-863 |
5.05e-34 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 140.81 E-value: 5.05e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 635 ARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDlDAFSPEEvKQFVETININCTLLLALINDILDLSRIESGTM 714
Cdd:PRK11466 433 ARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLAD-NPALNAQ-RDDLRAITDSGESLLTILNDILDYSAIEAGGK 510
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 715 -----DFKFGAFNLAFIMQEVHESqRLSmPRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVT 789
Cdd:PRK11466 511 nvsvsDEPFEPRPLLESTLQLMSG-RVK-GRPIRLATDIADDLPTALMGDPRRIRQVITNLLSNALRFTDEGSIVLRSRT 588
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796428172 790 NREGYTtIFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK11466 589 DGEQWL-VEVEDSGCGIDPAKLAEIFQPFVQVSGKRGGTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
620-863 |
8.74e-33 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 137.17 E-value: 8.74e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 620 QSIQRYKDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLLKDlDAFSPEEVKQFVETININCTLLLAL 699
Cdd:PRK09959 686 QDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSG-SGLSKEQRVEAISLAYATGQSLLGL 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 700 INDILDLSRIESGTMDFKFGAFNLAFIMQEV-HESQRLSMPRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAKKFT 778
Cdd:PRK09959 765 IGEILDVDKIESGNYQLQPQWVDIPTLVQNTcHSFGAIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFT 844
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 779 VTGSI----TFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQ--GAGLGLSICQTIVDRLHGSISVSSEL 852
Cdd:PRK09959 845 TEGAVkittSLGHIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQqtGSGLGLMICKELIKNMQGDLSLESHP 924
|
250
....*....|.
gi 2796428172 853 GKGTRFEVVIP 863
Cdd:PRK09959 925 GIGTTFTITIP 935
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
758-865 |
5.90e-31 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 117.36 E-value: 5.90e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 758 TDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKED---SFTQGAGLGLSI 834
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDHVEITVEDNGPGIPPEDLEKIFEPFFRTDkrsRKIGGTGLGLSI 80
|
90 100 110
....*....|....*....|....*....|.
gi 2796428172 835 CQTIVDRLHGSISVSSELGKGTRFEVVIPDA 865
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLPLE 111
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
649-863 |
1.45e-30 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 127.95 E-value: 1.45e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 649 FLANMSHEIRTPLNAIVGFSDLLKDlDAFSPEEV-KQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNLAFIM 727
Cdd:NF033092 375 FVANVSHELRTPLTTMRSYLEALAD-GAWKDPELaPRFLGVTQNETERMIRLVNDLLQLSRMDSKDYKLNKEWVNFNEFF 453
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 728 QEVheSQRLSM---PRDVELRIEIPEGEDKLVItDSVRLKQVVNNLINNAKKFTVT-GSITFgYVTNREGYTTIFVEDTG 803
Cdd:NF033092 454 NYI--IDRFEMilkNKNITFKREFPKRDLWVEI-DTDKITQVLDNIISNAIKYSPEgGTITF-RLLETHNRIIISISDQG 529
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796428172 804 SGISEDAQKHIFERFYKED---SFTQGA-GLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:NF033092 530 LGIPKKDLDKIFDRFYRVDkarSRKMGGtGLGLAIAKEVVEAHGGRIWAESEEGKGTTIYFTLP 593
|
|
| KinA |
COG5805 |
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle ... |
375-863 |
4.05e-30 |
|
Sporulation sensor histidine kinase A (Stage II sporulation protein SpoIIF/SpoIIJ) [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444507 [Multi-domain] Cd Length: 496 Bit Score: 125.23 E-value: 4.05e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 375 VEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSETYTSRFYEGQMAGSIFRIYMNGenilqdlLKKVRTGK 454
Cdd:COG5805 30 IEITEELETILENLPDAIIAVNREGKVIYINPAMEKLLGYTSEEIIGKTIFDFLEKEYHYRVKTR-------IERLQKGY 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 455 SPIPIPekafMQENHQGTYFPVSGEVVPIFANEKMTG----MAIVCRNISEEEMQR-RFFNMAVEESS---IYPWQYNMR 526
Cdd:COG5805 103 DVVMIE----QIYCKDGELIYVEVKLFPIYNQNGQAAilalRDITKKKKIEEILQEqEERLQTLIENSpdlICVIDTDGR 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 527 MnRFHFPGGLlRRFG-----YIGDTDLltrdemdALIHPEDLPHTRRNFDAIL-LGNEINSRMSFRLKsvDGSYEWWEFR 600
Cdd:COG5805 179 I-LFINESIE-RLFGapreeLIGKNLL-------ELLHPCDKEEFKERIESITeVWQEFIIEREIITK--DGRIRYFEAV 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 601 ST-AYDSLTVDTPYMVlgVCQSIQRYKDTEEALIaardralQADKLKSA--FLANMSHEIRTPLNAIVGFSDLLKDldaf 677
Cdd:COG5805 248 IVpLIDTDGSVKGILV--ILRDITEKKEAEELMA-------RSEKLSIAgqLAAGIAHEIRNPLTSIKGFLQLLQP---- 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 678 SPEEVKQFVETIninctlllalindILDLSRIESGTMDF---------KFGAFNLAFIMQEV---HESQrlSMPRDVELR 745
Cdd:COG5805 315 GIEDKEEYFDIM-------------LSELDRIESIISEFlalakpqavNKEKENINELIQDVvtlLETE--AILHNIQIR 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 746 IEIPEgEDKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEds 823
Cdd:COG5805 380 LELLD-EDPFIYCDENQIKQVFINLIKNAIEAMPNGGTITIHTEEEDNSVIIRVIDEGIGIPEERLKKLGEPFFttKE-- 456
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2796428172 824 ftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG5805 457 --KGTGLGLMVSYKIIENHNGTIDIDSKVGKGTTFTITLP 494
|
|
| HATPase_EvgS-ArcB-TorS-like |
cd16922 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid ... |
763-863 |
1.23e-29 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases, many are hybrid sensor histidine kinases, similar to Escherichia coli EvgS, ArcB, TorS, BarA, RcsC; This family contains the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinases (HKs), including the following Escherichia coli HKs: EvgS, a HK of the EvgS-EvgA two-component system (TCS) that confers acid resistance; ArcB, a HK of the ArcB-ArcA TCS that modulates the expression of numerous genes in response to respiratory growth conditions; TorS, a HK of the TorS-TorR TCS which is involved in the anaerobic utilization of trimethylamine-N-oxide; BarA, a HK of the BarA-UvrY TCS involved in the regulation of carbon metabolism; and RcsC, a HK of the RcsB-RcsC TCS which regulates the expression of the capsule operon and of the cell division gene ftsZ. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), with most having accessory sensor domain(s) such as GAF, PAS and CHASE; many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340399 [Multi-domain] Cd Length: 110 Bit Score: 113.36 E-value: 1.23e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGSITF----GYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSFT----QGAGLGLSI 834
Cdd:cd16922 1 LRQILLNLLGNAIKFTEEGEVTLrvslEEEEEDGVQLRFSVEDTGIGIPEEQQARLFEPFSQADSSTtrkyGGTGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 2796428172 835 CQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16922 81 SKKLVELMGGDISVESEPGQGSTFTFTLP 109
|
|
| HATPase |
cd00075 |
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ... |
763-862 |
2.44e-29 |
|
Histidine kinase-like ATPase domain; This superfamily includes the histidine kinase-like ATPase (HATPase) domains of several ATP-binding proteins such as histidine kinase, DNA gyrase B, topoisomerases, heat shock protein 90 (HSP90), phytochrome-like ATPases and DNA mismatch repair proteins. Domains belonging to this superfamily are also referred to as GHKL (gyrase, heat-shock protein 90, histidine kinase, MutL) ATPase domains.
Pssm-ID: 340391 [Multi-domain] Cd Length: 102 Bit Score: 112.31 E-value: 2.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGS-ITFGyVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSF--TQGAGLGLSICQTIV 839
Cdd:cd00075 1 LEQVLSNLLDNALKYSPPGGtIEIS-LRQEGDGVVLEVEDNGPGIPEEDLERIFERFYRGDKSreGGGTGLGLAIVRRIV 79
|
90 100
....*....|....*....|...
gi 2796428172 840 DRLHGSISVSSELGKGTRFEVVI 862
Cdd:cd00075 80 EAHGGRITVESEPGGGTTFTVTL 102
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
758-866 |
2.14e-27 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 107.07 E-value: 2.14e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 758 TDSVRLKQVVNNLINNAKKFTVTGSItfGYVT-NREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQ-GAGLGLSIC 835
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGE--ITVTlSEGGELTLTVEDNGIGIPPEDLPRIFEPFSTADKRGGgGTGLGLSIV 78
|
90 100 110
....*....|....*....|....*....|.
gi 2796428172 836 QTIVDRLHGSISVSSELGKGTRFEVVIPDAN 866
Cdd:pfam02518 79 RKLVELLGGTITVESEPGGGTTVTLTLPLAQ 109
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
626-863 |
1.22e-26 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 114.41 E-value: 1.22e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 626 KDTEEALIAARDRALQADKLKSAFLANMSHEIRTPLNAIVGFSDLlkdldAFS-PEEVKQFVETININC---TLLLALIN 701
Cdd:TIGR01386 221 RELAQSFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQV-----ALSqPRTGEEYREVLESNLeelERLSRMVS 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 702 DILDLSRIESGTMDFKFGAFNLAFIMQEVHES-QRLSMPRDVELRIeipEGEdKLVITDSVRLKQVVNNLINNAKKFTVT 780
Cdd:TIGR01386 296 DMLFLARADNGQLALERVRLDLAAELAKVAEYfEPLAEERGVRIRV---EGE-GLVRGDPQMFRRAISNLLSNALRHTPD 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 781 GSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSF----TQGAGLGLSICQTIVDRLHGSISVSSELGKgT 856
Cdd:TIGR01386 372 GGTITVRIERRSDEVRVSVSNPGPGIPPEHLSRLFDRFYRVDPArsnsGEGTGLGLAIVRSIMEAHGGRASAESPDGK-T 450
|
....*..
gi 2796428172 857 RFEVVIP 863
Cdd:TIGR01386 451 RFILRFP 457
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
641-863 |
6.57e-25 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 109.15 E-value: 6.57e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 641 QADKLKSAFLANMSHEIRTPLNAIVGFSDLLKD-LDAFSPEEVKQFVETINInctlLLALINDILDLSRIESGTMDFKFG 719
Cdd:NF012163 235 KNEQMRRDFMADISHELRTPLAVLRAELEAIQDgIRKFTPESLDSLQAEVGT----LTKLVDDLHDLSMSDEGALAYQKA 310
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 720 AFNL-AFIMQEVHESQRLSMPRDVELRIEIPEGedKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIF 798
Cdd:NF012163 311 SVDLvPLLEVEGGAFRERFASAGLELEVSLPDS--SLVFGDRDRLMQLFNNLLENSLRYTDSGGSLHISASQRPKEVTLT 388
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 799 VEDTGSGISEDAQKHIFERFYK-EDSFTQ---GAGLGLSICQTIVDRLHGSISVS-SELGkGTRFEVVIP 863
Cdd:NF012163 389 VADSAPGVSDEQLARLFERFYRvEVSRNRasgGSGLGLAISLNIVQAHGGTLHAAhSPLG-GLRIVVTLP 457
|
|
| KinB |
COG5806 |
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome ... |
633-863 |
4.93e-24 |
|
Sporulation sensor histidine kinase B [Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 444508 [Multi-domain] Cd Length: 412 Bit Score: 105.72 E-value: 4.93e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 633 IAARDRALQADKLK--SAFLANMSHEIRTPLNAIVGFSDLLKDLDAfSPEEVKQFVEtininctLLL-------ALINDI 703
Cdd:COG5806 186 ILLRKELQRAEKLEvvSELAASIAHEVRNPLTVVRGFIQLLQEPEL-SDEKRKQYIR-------IALeeldraeAIITDY 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 704 LDLSRIESGTMDFkfgaFNLAfimQEVHESQRLSMP----RDVELRIEIPEGedKLVITDSVRLKQVVNNLINNAKKFTV 779
Cdd:COG5806 258 LTFAKPQPEKLEK----IDVS---EELEHVIDVLSPyanmNNVEIQTELEPG--LYIEGDRQKLQQCLINIIKNGIEAMP 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 780 TGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEdsftQGAGLGLSICQTIVDRLHGSISVSSELGKGTR 857
Cdd:COG5806 329 NGGTLTIDVSIDKNKVIISIKDTGVGMTKEQLERLGEPYFstKE----KGTGLGTMVSYRIIEAMNGTIRVESEVGKGTT 404
|
....*.
gi 2796428172 858 FEVVIP 863
Cdd:COG5806 405 FTITLP 410
|
|
| PRK13837 |
PRK13837 |
two-component system VirA-like sensor kinase; |
618-863 |
3.15e-23 |
|
two-component system VirA-like sensor kinase;
Pssm-ID: 237526 [Multi-domain] Cd Length: 828 Bit Score: 105.92 E-value: 3.15e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 618 VCQSIQRYKDTEEALIAARdRALQADKLKS--AFLANMSHEIRTPLNAIVGFSDLLKDLDAFSPEEVKQFVETINincTL 695
Cdd:PRK13837 421 LAHAIERRRLETERDALER-RLEHARRLEAvgTLASGIAHNFNNILGAILGYAEMALNKLARHSRAARYIDEIIS---AG 496
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 696 LLA--LINDILDLSRIESGTMDfkfgAFNLAFIMQEVHESQRLSMPRDVELRIEIpEGEDKLVITDSVRLKQVVNNLINN 773
Cdd:PRK13837 497 ARArlIIDQILAFGRKGERNTK----PFDLSELVTEIAPLLRVSLPPGVELDFDQ-DQEPAVVEGNPAELQQVLMNLCSN 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 774 A----------------KKFTVTGSITFGYVTNREgYTTIFVEDTGSGISEDAQKHIFERFykedsFT---QGAGLGLSI 834
Cdd:PRK13837 572 AaqamdgagrvdislsrAKLRAPKVLSHGVLPPGR-YVLLRVSDTGAGIDEAVLPHIFEPF-----FTtraGGTGLGLAT 645
|
250 260
....*....|....*....|....*....
gi 2796428172 835 CQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK13837 646 VHGIVSAHAGYIDVQSTVGRGTRFDVYLP 674
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
652-863 |
3.31e-22 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 101.07 E-value: 3.31e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 652 NMSHEIRTPLNAIVGFSDLLKDldAFSPEEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNLAFIMQEVH 731
Cdd:PRK11100 262 TLTHELKSPLAAIRGAAELLQE--DPPPEDRARFTGNILTQSARLQQLIDRLLELARLEQRQELEVLEPVALAALLEELV 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 732 ESQ--RLSMpRDVELRIEIPEGEdklVITDSVRLKQVVNNLINNAKKFTVTGS-ITFGyVTNREGYTTIFVEDTGSGISE 808
Cdd:PRK11100 340 EAReaQAAA-KGITLRLRPDDAR---VLGDPFLLRQALGNLLDNAIDFSPEGGtITLS-AEVDGEQVALSVEDQGPGIPD 414
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2796428172 809 DAQKHIFERFY---KEDSFTQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK11100 415 YALPRIFERFYslpRPANGRKSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
644-863 |
4.02e-22 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 99.26 E-value: 4.02e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 644 KLKSAFLANMSHEIRTPLNAIVGFSDLLK-----DLDAFSPEEVKQF-------VETINinctlllALINDILDLSRIES 711
Cdd:PRK09303 149 KFKDRVLAMLAHDLRTPLTAASLALETLElgqidEDTELKPALIEQLqdqarrqLEEIE-------RLITDLLEVGRTRW 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 712 GTMDFKFGAFNLAFIMQEV-HESQRLSMPRDVELRIEIPEgeD-KLVITDSVRLKQVVNNLINNAKKFTVT-GSITFGyV 788
Cdd:PRK09303 222 EALRFNPQKLDLGSLCQEViLELEKRWLAKSLEIQTDIPS--DlPSVYADQERIRQVLLNLLDNAIKYTPEgGTITLS-M 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 789 TNRegyTTIFVE----DTGSGISEDAQKHIFE-RF-YKEDSFTQGAGLGLSICQTIVdRLH-GSISVSSELGKGTRFEVV 861
Cdd:PRK09303 299 LHR---TTQKVQvsicDTGPGIPEEEQERIFEdRVrLPRDEGTEGYGIGLSVCRRIV-RVHyGQIWVDSEPGQGSCFHFT 374
|
..
gi 2796428172 862 IP 863
Cdd:PRK09303 375 LP 376
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
3.19e-21 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 89.40 E-value: 3.19e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAkkftVTGSITFGYVTNREGYTT----IFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTI 838
Cdd:cd16943 4 LNQVLLNLLVNA----AQAMEGRGRITIRTWAHVdqvlIEVEDTGSGIDPEILGRIFDPFFTTKPVGEGTGLGLSLSYRI 79
|
90 100
....*....|....*....|....*
gi 2796428172 839 VDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16943 80 IQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
644-863 |
7.06e-21 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 97.02 E-value: 7.06e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 644 KLKSAFLANMSHEIRTPLNAIVGFSDLLKD-LDAFSPeEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFN 722
Cdd:NF040691 269 RLQQRFVSDVSHELRTPLTTIRMAADVIHDsRDDFDP-ATARSAELLHTELDRFESLLSDLLEISRFDAGAAELDVEPVD 347
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 723 LAFIMQEVHESQR-LSMPRDVELRIEIPeGEDKLVITDSVRLKQVVNNLINNA------KKFTVTgsitfgyVTNREGYT 795
Cdd:NF040691 348 LRPLVRRVVDALRqLAERAGVELRVDAP-GTPVVAEVDPRRVERVLRNLVVNAiehgegKPVVVT-------VAQDDTAV 419
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796428172 796 TIFVEDTGSGISEDAQKHIFERFYKEDS----FTQGAGLGLSICqtIVD-RLH-GSISVSSELGKGTRFEVVIP 863
Cdd:NF040691 420 AVTVRDHGVGLKPGEVALVFDRFWRADPararTTGGTGLGLAIA--LEDaRLHgGWLEAWGRPGQGSQFRLTLP 491
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
630-863 |
2.04e-20 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 95.08 E-value: 2.04e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 630 EALIAARDrALQADKLKSA---FLANMSHEIRTPLNAIVGFSDLLKDLDAFSPEEVKQfVETININCTLLLALINDILDL 706
Cdd:PRK11006 186 QLLMVARD-VTQMHQLEGArrnFFANVSHELRTPLTVLQGYLEMMQDQPLEGALREKA-LHTMREQTQRMEGLVKQLLTL 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 707 SRIESGTMdfkfgafnlaFIMQEV-----------HESQRLSMPRDvELRIEIpegEDKL-VITDSVRLKQVVNNLINNA 774
Cdd:PRK11006 264 SKIEAAPT----------IDLNEKvdvpmmlrvleREAQTLSQGKH-TITFEV---DNSLkVFGNEDQLRSAISNLVYNA 329
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 775 KKFTVTGS-ITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFYKEDSF----TQGAGLGLSICQTIVDRLHGSISVS 849
Cdd:PRK11006 330 VNHTPEGThITVRWQRVPQG-AEFSVEDNGPGIAPEHIPRLTERFYRVDKArsrqTGGSGLGLAIVKHALSHHDSRLEIE 408
|
250
....*....|....
gi 2796428172 850 SELGKGTRFEVVIP 863
Cdd:PRK11006 409 SEVGKGTRFSFVLP 422
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
631-863 |
2.17e-20 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 96.19 E-value: 2.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 631 ALIAARDRALQADKLKS--AFLANMSHEIRTPLNAIVGFSDLL--KDLDAFSPE---EVKQFVETINinctlllALINDI 703
Cdd:PRK11360 373 ERKRLQRRVARQERLAAlgELVAGVAHEIRNPLTAIRGYVQIWrqQTSDPPSQEylsVVLREVDRLN-------KVIDQL 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 704 LDLSRIESGTM---DFKFGAFNLAFIMQEVHESQRLSMPRDVELriEIPegedkLVITDSVRLKQVVNNLINNA-KKFTV 779
Cdd:PRK11360 446 LEFSRPRESQWqpvSLNALVEEVLQLFQTAGVQARVDFETELDN--ELP-----PIWADPELLKQVLLNILINAvQAISA 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 780 TGSITF--GYVTNREGYTTIfvEDTGSGISEDAQKHIFERFykedsFT---QGAGLGLSICQTIVDRLHGSISVSSELGK 854
Cdd:PRK11360 519 RGKIRIrtWQYSDGQVAVSI--EDNGCGIDPELLKKIFDPF-----FTtkaKGTGLGLALSQRIINAHGGDIEVESEPGV 591
|
....*....
gi 2796428172 855 GTRFEVVIP 863
Cdd:PRK11360 592 GTTFTLYLP 600
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
623-863 |
3.06e-20 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 96.64 E-value: 3.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 623 QRYKDTEEALIA-ARDR----------ALQADK--LKSAFLANMSHEIRTPLNAIVGFSDLLK-DLDAF-SP--EEVKQF 685
Cdd:PRK10490 628 QRLLETFTLLIAnALERltltaseeqaRLASEReqLRNALLAALSHDLRTPLTVLFGQAEILTlDLASEgSPhaRQASEI 707
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 686 VETInINCTlllALINDILDLSRIESGtmdfkfgAFNLA---FIMQEVHESQRLSMP---RDVELRIEIPEgEDKLVITD 759
Cdd:PRK10490 708 RQQV-LNTT---RLVNNLLDMARIQSG-------GFNLRkewLTLEEVVGSALQMLEpglSGHPINLSLPE-PLTLIHVD 775
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 760 SVRLKQVVNNLINNAKKFTvtGSITFGYVTNREGYTTIFVE--DTGSGISEDAQKHIFERF---YKEdSFTQGAGLGLSI 834
Cdd:PRK10490 776 GPLFERVLINLLENAVKYA--GAQAEIGIDAHVEGERLQLDvwDNGPGIPPGQEQLIFDKFargNKE-SAIPGVGLGLAI 852
|
250 260
....*....|....*....|....*....
gi 2796428172 835 CQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK10490 853 CRAIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
752-860 |
4.09e-20 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 86.31 E-value: 4.09e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 752 EDKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFYKED-SFTQGAGL 830
Cdd:cd16940 3 ADIQVQGDALLLFLLLRNLVDNAVRYSPQGSRVEIKLSADDG-AVIRVEDNGPGIDEEELEALFERFYRSDgQNYGGSGL 81
|
90 100 110
....*....|....*....|....*....|
gi 2796428172 831 GLSICQTIVDRLHGSISVSSELGKGTRFEV 860
Cdd:cd16940 82 GLSIVKRIVELHGGQIFLGNAQGGGLEAWV 111
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
646-712 |
4.95e-20 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 84.57 E-value: 4.95e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796428172 646 KSAFLANMSHEIRTPLNAIVGFSDLLKDLDAfsPEEVKQFVETININCTLLLALINDILDLSRIESG 712
Cdd:pfam00512 2 KSEFLANLSHELRTPLTAIRGYLELLRDEKL--DEEQREYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
654-867 |
1.49e-19 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 91.83 E-value: 1.49e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 654 SHEIRTPLNAIVGFSDLLKdldafsPEEVKQFVETININctlLLALINDILdlSRIESGTMDfkfgafnlAFI---MQEV 730
Cdd:COG3290 197 RHDFRNHLHTISGLLQLGE------YDEALEYIDEISEE---LQELIDSLL--SRIGNPVLA--------ALLlgkAARA 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 731 HEsqrlsmpRDVELRIEIPEGEDKLVITDSVrLKQVVNNLINNA-----KKFTVTGSITFgYVTNREGYTTIFVEDTGSG 805
Cdd:COG3290 258 RE-------RGIDLTIDIDSDLPDLPLSDTD-LVTILGNLLDNAieaveKLPEEERRVEL-SIRDDGDELVIEVEDSGPG 328
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2796428172 806 ISEDAQKHIFERFY--KEDsftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIPDANE 867
Cdd:COG3290 329 IPEELLEKIFERGFstKLG---EGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLPKEGE 389
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
648-863 |
2.22e-19 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 92.00 E-value: 2.22e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 648 AFLANMSHEIRTPLNAIVGFSDLLKD-LDAFSPEEVKQFVETInincTLLLALINDILDLSRIESGTMDFKFGAFNLAFI 726
Cdd:PRK10549 242 DFMADISHELRTPLAVLRGELEAIQDgVRKFTPESVASLQAEV----GTLTKLVDDLHQLSLSDEGALAYRKTPVDLVPL 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 727 MQEVHESQRLSMpRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAKKFTVTGS---ITFGYvtnREGYTTIFVEDTG 803
Cdd:PRK10549 318 LEVAGGAFRERF-ASRGLTLQLSLPDSATVFGDPDRLMQLFNNLLENSLRYTDSGGslhISAEQ---RDKTLRLTFADSA 393
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2796428172 804 SGISEDAQKHIFERFYKEDS----FTQGAGLGLSICQTIVDRLHGSISVS-SELGkGTRFEVVIP 863
Cdd:PRK10549 394 PGVSDEQLQKLFERFYRTEGsrnrASGGSGLGLAICLNIVEAHNGRIIAAhSPFG-GVSITVELP 457
|
|
| COG2984 |
COG2984 |
ABC-type uncharacterized transport system, periplasmic component [General function prediction ... |
26-309 |
3.64e-19 |
|
ABC-type uncharacterized transport system, periplasmic component [General function prediction only];
Pssm-ID: 442223 Cd Length: 284 Bit Score: 88.81 E-value: 3.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 26 RTYNVLFIQ-SYtkntpwHSLLTENLE---NGLDKGGVKANITTEYLNADYWSFasecfIMRRICERARQRKTDLIVTSS 101
Cdd:COG2984 1 KPKKIGILQiSE------HPALDAAREgfkDGLAEAGYGKNLKLDYQNAQGDQA-----TAAQIAAKLVADKPDLIVAIG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 102 DEAFFTLThcgdSLPYQIPVVVSGIKYPDE-----RVFERMPNVSGYVSKTDFDVLLDAAVRMFPSRRELVCLSDSSFLS 176
Cdd:COG2984 70 TPAAQAAA----NATKDIPVVFTAVTDPVGaglvkSLEKPGGNVTGVSDLLPIEKQLELIKKLLPDAKRIGVLYNPSEAN 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 177 lkGVKTVEEswerIKSNYPEHELKVLNVQAKSLNSIITS------------ICYDYNAYKHIviapKWIPFLSLKLKAPV 244
Cdd:COG2984 146 --SVAQVEE----LKKAAKKLGLELVEATVTSSNEIQQAlqslagkvdaiyVPTDNTVVSAL----EAIAKVAARAKIPV 215
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2796428172 245 FTSQNLAMTNGVLCVYDAVPGEDAFAAGRQAASILKGKSPASLGV---KDFggKLLFDYKQLQFFRVN 309
Cdd:COG2984 216 FGGDDSSVKAGALAGYGIDYYELGRQAAEMALRILKGEKPADIPVetpKKF--ELVINLKTAKALGIT 281
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
759-863 |
4.14e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 83.28 E-value: 4.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 759 DSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDS----FTQGAGLGLSI 834
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTDTGGKLRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESsrnrASGGSGLGLAI 80
|
90 100 110
....*....|....*....|....*....|
gi 2796428172 835 CQTIVDRLHGSISVS-SELGkGTRFEVVIP 863
Cdd:cd16946 81 CHNIALAHGGTISAEhSPLG-GLRLVLTLP 109
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
5.55e-19 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 82.83 E-value: 5.55e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTV-----TGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSftQGAGLGLSICQT 837
Cdd:cd16920 1 IQQVLINLVRNGIEAMSeggceRRELTIRTSPADDRAVTISVKDTGPGIAEEVAGQLFDPFYTTKS--EGLGMGLSICRS 78
|
90 100
....*....|....*....|....*.
gi 2796428172 838 IVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16920 79 IIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
646-712 |
7.59e-19 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 81.07 E-value: 7.59e-19
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796428172 646 KSAFLANMSHEIRTPLNAIVGFSDLLKDLDAfsPEEVKQFVETININCTLLLALINDILDLSRIESG 712
Cdd:smart00388 2 KREFLANLSHELRTPLTAIRGYLELLLDTEL--SEEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
627-858 |
2.52e-18 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 88.51 E-value: 2.52e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 627 DTEEALIAArdralqadklKSAFLANMSHEIRTPLnaiVGFSDLLKDLDAFSPEEVkqfvETININCTLLLALINDILDL 706
Cdd:PRK10604 203 DNINALIAS----------KKQLIDGIAHELRTPL---VRLRYRLEMSDNLSAAES----QALNRDIGQLEALIEELLTY 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 707 SRIESGTMDFKFGAFNLAFIMQEVHESQRLSMPrDVELRIEIPEGEDKLVItDSVRLKQVVNNLINNAKKF---TVTGSI 783
Cdd:PRK10604 266 ARLDRPQNELHLSEPDLPAWLSTHLADIQAVTP-EKTVRLDTPHQGDYGAL-DMRLMERVLDNLLNNALRYahsRVRVSL 343
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 784 TFgyvtnREGYTTIFVEDTGSGISEDAQKHIFERFYK----EDSFTQGAGLGLSICQTIVDRLHGSISV-SSELGkGTRF 858
Cdd:PRK10604 344 LL-----DGNQACLIVEDDGPGIPPEERERVFEPFVRldpsRDRATGGCGLGLAIVHSIALAMGGSVNCdESELG-GARF 417
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
646-865 |
6.69e-18 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 87.52 E-value: 6.69e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 646 KSAFLANMSHEIRTPLNAIVGFSDLLKDLDAfSPEEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNLAf 725
Cdd:PRK09835 262 QSNFSADIAHEIRTPITNLITQTEIALSQSR-SQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKKMLDLA- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 726 imQEVHES----QRLSMPRDVELRIEipeGEDKLVITDSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVED 801
Cdd:PRK09835 340 --DEVGKVfdffEAWAEERGVELRFV---GDPCQVAGDPLMLRRAISNLLSNALRYTPAGEAITVRCQEVDHQVQLVVEN 414
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2796428172 802 TGSGISEDAQKHIFERFYKEDSFTQ----GAGLGLSICQTIVDRLHGSISVSSELgKGTRFEVVIPDA 865
Cdd:PRK09835 415 PGTPIAPEHLPRLFDRFYRVDPSRQrkgeGSGIGLAIVKSIVVAHKGTVAVTSDA-RGTRFVISLPRL 481
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
643-708 |
4.29e-17 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 76.10 E-value: 4.29e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2796428172 643 DKLKSAFLANMSHEIRTPLNAIVGFSDLLKDlDAFSPEEVKQFVETININCTLLLALINDILDLSR 708
Cdd:cd00082 1 LQAKGEFLANVSHELRTPLTAIRGALELLEE-ELLDDEEQREYLERIREEAERLLRLINDLLDLSR 65
|
|
| HATPase_PhoQ-like |
cd16954 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
722-862 |
1.69e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli PhoQ and Providencia stuartii AarG. PhoQ is the histidine kinase (HK) of the PhoP-PhoQ two-component regulatory system (TCS), which responds to the levels of Mg2+ and Ca2+, controls virulence, mediates the adaptation to Mg2+-limiting environments, and regulates numerous cellular activities. Providencia stuartii AarG is a putative sensor kinase which controls the expression of the 2'-N-acetyltransferase and an intrinsic multiple antibiotic resistance (Mar) response in Providencia stuartii. The AarG product is similar to PhoQ in that it is able to restore wild-type levels of resistance to a Salmonella typhimurium phoQ mutant. However, the expression of the 2'-N-acetyltransferase gene and of aarP (a gene encoding a transcriptional activator of 2'-N-acetyltransferase) are not significantly affected by the levels of Mg2+ or Ca2+. Most proteins in this group contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have an accessory HAMP sensor domain, and some have an intracellular membrane -interaction PhoQ sensor domain.
Pssm-ID: 340430 [Multi-domain] Cd Length: 135 Bit Score: 76.90 E-value: 1.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 722 NLAFIMQEVHESQRLSMPRDVELRIEIP-EGEDklvitdsvrLKQVVNNLINNAKKFtvtgSITFGYVTNR--EGYTTIF 798
Cdd:cd16954 5 SLCSALNKVYQRKGVSISLDISPELRFPgERND---------LMELLGNLLDNACKW----CLEFVEVTARqtDGGLHLI 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2796428172 799 VEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTIVDRLHGSISVS-SELGkGTRFEVVI 862
Cdd:cd16954 72 VDDDGPGVPESQRSKIFQRGQRLDEQRPGQGLGLAIAKEIVEQYGGELSLSdSPLG-GARFEVVF 135
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
637-863 |
2.38e-16 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 82.27 E-value: 2.38e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 637 DRALqadklksaFLANMSHEIRTPLNAIVGFSDLLKDLDAFSPEEVKQFVETINinctlllALINDILDLSRIESGtMDF 716
Cdd:PRK09467 228 DRTL--------LMAGVSHDLRTPLTRIRLATEMMSEEDGYLAESINKDIEECN-------AIIEQFIDYLRTGQE-MPM 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 717 KFGAFNLafIMQEVHESQrlsMPRDVELRIEIPEGEDKLVItDSVRLKQVVNNLINNAKKFTvTG--SITFGYVTNREGY 794
Cdd:PRK09467 292 EMADLNA--LLGEVIAAE---SGYEREIETALQPGPIEVPM-NPIAIKRALANLVVNAARYG-NGwiKVSSGTEGKRAWF 364
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2796428172 795 TtifVEDTGSGISEDAQKHIFERFYKEDSF--TQGAGLGLSICQTIVDRLHGSISVS-SELGkGTRFEVVIP 863
Cdd:PRK09467 365 Q---VEDDGPGIPPEQLKHLFQPFTRGDSArgSSGTGLGLAIVKRIVDQHNGKVELGnSEEG-GLSARAWLP 432
|
|
| HATPase_FilI-like |
cd16921 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
8.47e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Methanosaeta harundinacea FilI and some hybrid sensor histidine kinases; This family includes FilI, the histidine kinase (HK) component of FilI-FilRs, a two-component signal transduction system (TCS) of the methanogenic archaeon, Methanosaeta harundinacea, which is involved in regulating methanogenesis. The cytoplasmic HK core consists of a C-terminal HK-like ATPase domain (represented here) and a histidine kinase dimerization and phosphoacceptor domain (HisKA) domain, which, in FilI, are coupled to CHASE, HAMP, PAS, and GAF sensor domains. FilI-FilRs catalyzes the phosphotransfer between FilI (HK) and FilRs (FilR1 and FilR2, response regulators) of the TCS. TCSs are predicted to be of bacterial origin, and acquired by archaea by horizontal gene transfer. This model also includes related HATPase domains such as that of Synechocystis sp. PCC6803 phytochrome-like protein Cph1. Proteins having this HATPase domain and HisKA domain also have accessory sensor domains such as CHASE, GAF, HAMP and PAS; some are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340398 [Multi-domain] Cd Length: 105 Bit Score: 73.90 E-value: 8.47e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFT---VTGSITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFYK--EDSFTQGAGLGLSICQT 837
Cdd:cd16921 1 LGQVLTNLLGNAIKFRrprRPPRIEVGAEDVGEE-WTFYVRDNGIGIDPEYAEKVFGIFQRlhSREEYEGTGVGLAIVRK 79
|
90 100
....*....|....*....|....*.
gi 2796428172 838 IVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16921 80 IIERHGGRIWLESEPGEGTTFYFTLP 105
|
|
| HATPase_YcbM-like |
cd16947 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-860 |
9.69e-16 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis YcbM; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis YcbM, a HK of the two-component system YcbM-YcbL. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA).
Pssm-ID: 340423 [Multi-domain] Cd Length: 125 Bit Score: 74.47 E-value: 9.69e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYK-EDSFT---QGAGLGLSICQTI 838
Cdd:cd16947 21 LQRILKNLISNAIKYGSDGKFLGMTLREDEKHVYIDIWDKGKGISETEKDHVFERLYTlEDSRNsakQGNGLGLTITKRL 100
|
90 100
....*....|....*....|..
gi 2796428172 839 VDRLHGSISVSSELGKGTRFEV 860
Cdd:cd16947 101 AESMGGSIYVNSKPYEKTVFTV 122
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
623-867 |
1.91e-15 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 79.83 E-value: 1.91e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 623 QRYKDTEEALIAARDRalqadKLKSAFL----ANMSHEIRTPLNAIVGFSdllKDLDAFSPE--EVKQFVETININCTLL 696
Cdd:PRK10364 215 RRYLRSRQLLQDEMKR-----KEKLVALghlaAGVAHEIRNPLSSIKGLA---KYFAERAPAggEAHQLAQVMAKEADRL 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 697 LALINDILDLSRiesgTMDFKFGAFNLAFIMQevHESQRLSM---PRDVELRIEIPEGEdKLVITDSVRLKQVVNNLINN 773
Cdd:PRK10364 287 NRVVSELLELVK----PTHLALQAVDLNDLIN--HSLQLVSQdanSREIQLRFTANDTL-PEIQADPDRLTQVLLNLYLN 359
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 774 A-KKFTVTGSITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFykedsFT---QGAGLGLSICQTIVDRLHGSISVS 849
Cdd:PRK10364 360 AiQAIGQHGVISVTASESGAG-VKISVTDSGKGIAADQLEAIFTPY-----FTtkaEGTGLGLAVVHNIVEQHGGTIQVA 433
|
250
....*....|....*...
gi 2796428172 850 SELGKGTRFEVVIPDANE 867
Cdd:PRK10364 434 SQEGKGATFTLWLPVNIT 451
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
759-863 |
7.50e-15 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 71.37 E-value: 7.50e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 759 DSVRLKQVVNNLINNAKKFTVTGS-ITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYK-EDSFTQ---GAGLGLS 833
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFTPDGGrIRCILEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQgDGSSTRahgGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 2796428172 834 ICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
371-632 |
2.52e-14 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 73.91 E-value: 2.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 371 QHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSEtytsrfyegQMAGSIFRIYMNGENIlQDLLKKV 450
Cdd:COG2202 3 EEALEESERRLRALVESSPDAIIITDLDGRILYVNPAFERLTGYSAE---------ELLGKTLRDLLPPEDD-DEFLELL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 451 RTGKSPIPIPEKAFMQENHQGTYFPVSGEVVPIF-ANEKMTGMAIVCRNIS-----EEEMQR--RFFNMAVEESSIYPWQ 522
Cdd:COG2202 73 RAALAGGGVWRGELRNRRKDGSLFWVELSISPVRdEDGEITGFVGIARDITerkraEEALREseERLRLLVENAPDGIFV 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 523 YNMRMNRFHFPGGLLRRFGYIGDtDLLTRDEMDaLIHPEDLPHTRRNFDAILLGNEINSRMSFRLKSVDGsyEWWEFRST 602
Cdd:COG2202 153 LDLDGRILYVNPAAEELLGYSPE-ELLGKSLLD-LLHPEDRERLLELLRRLLEGGRESYELELRLKDGDG--RWVWVEAS 228
|
250 260 270
....*....|....*....|....*....|
gi 2796428172 603 AYDSLTVDTPYMVLGVCQSIQRYKDTEEAL 632
Cdd:COG2202 229 AVPLRDGGEVIGVLGIVRDITERKRAEEAL 258
|
|
| PRK11086 |
PRK11086 |
sensory histidine kinase DcuS; Provisional |
748-863 |
2.75e-14 |
|
sensory histidine kinase DcuS; Provisional
Pssm-ID: 236839 [Multi-domain] Cd Length: 542 Bit Score: 76.49 E-value: 2.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 748 IPEGEDKLVITDsvrLKQVVNNLINNA-----KKFTVTGSITFGYvtnREGYTTIFVEDTGSGISEDAQKHIFERFYKed 822
Cdd:PRK11086 422 LPDSGDEDQVHE---LITILGNLIENAleavgGEEGGEISVSLHY---RNGWLHCEVSDDGPGIAPDEIDAIFDKGYS-- 493
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 2796428172 823 sfTQGA--GLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK11086 494 --TKGSnrGVGLYLVKQSVENLGGSIAVESEPGVGTQFFVQIP 534
|
|
| HATPase_BvrS-ChvG-like |
cd16953 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
3.85e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Brucella abortus BvrS and Sinorhizobium meliloti ChvG; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Brucella abortus BvrS of the BvrR-BvrS two-component regulatory system (TCS), which controls cell invasion and intracellular survival, as well as Sinorhizobium meliloti and Agrobacterium tumefaciens ChvG of the ChvI-ChvG TCS necessary for endosymbiosis and pathogenicity in plants. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), an accessory HAMP sensor domain, a periplasmic stimulus-sensing domain, and some also have a sensor N-terminal transmembrane domain.
Pssm-ID: 340429 [Multi-domain] Cd Length: 110 Bit Score: 69.14 E-value: 3.85e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFT--VTGSITFGYVTNREGYTtIFVEDTGSGISEDAQKHIFERFYKE----DSFTQGAGLGLSICQ 836
Cdd:cd16953 1 LGQVLRNLIGNAISFSppDTGRITVSAMPTGKMVT-ISVEDEGPGIPQEKLESIFDRFYTErpanEAFGQHSGLGLSISR 79
|
90 100 110
....*....|....*....|....*....|..
gi 2796428172 837 TIVDrLHGSISVSS-----ELGKGTRFEVVIP 863
Cdd:cd16953 80 QIIE-AHGGISVAEnhnqpGQVIGARFTVQLP 110
|
|
| HATPase_EcPhoR-like |
cd16952 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-865 |
4.34e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli PhoR; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Escherichia coli or Vibrio cholera PhoR, the histidine kinase (HK) of PhoB-PhoR a two-component signal transduction system (TCS) involved in phosphate regulation. PhoR monitors extracellular inorganic phosphate (Pi) availability and PhoB, the response regulator, regulates transcription of genes of the phosphate regulon. PhoR is a bifunctional histidine autokinase/phospho-PhoB phosphatase; in phosphate deficiency, it autophosphorylates and Pi is transferred to PhoB, and when environmental Pi is abundant, it removes the phosphoryl group from phosphorylated PhoB. Other roles of PhoB-PhoR TCS have been described, including motility, biofilm formation, intestinal colonization, and virulence in V. cholera. E.coli PhoR and Bacillus subtilis PhoR (whose HATPase domain belongs to a different family) sense very different signals in each bacterium. In E. coli the PhoR signal comes from phosphate transport mediated by the PstSCAB2 phosphate transporter and the PhoU chaperone-like protein while in B. subtilis, the PhoR activation signal comes from wall teichoic acid (WTA) metabolism.
Pssm-ID: 340428 [Multi-domain] Cd Length: 108 Bit Score: 69.15 E-value: 4.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTV-TGSITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFYKEDSF----TQGAGLGLSICQT 837
Cdd:cd16952 1 LRSAFSNLVSNAVKYTPpSDTITVRWSQEESG-ARLSVEDTGPGIPPEHIPRLTERFYRVDIErcrnTGGTGLGLAIVKH 79
|
90 100
....*....|....*....|....*...
gi 2796428172 838 IVDRLHGSISVSSELGKGTRFEVVIPDA 865
Cdd:cd16952 80 VMSRHDARLLIASELGKGSRFTCLFPSS 107
|
|
| HATPase_CckA-like |
cd16919 |
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar ... |
794-863 |
4.83e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor hybrid histidine kinases, similar to Brucella abortus 2308 CckA; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) similar to Brucella abortus 2308 CckA, which is a component of an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival; phosphoryl transfer initiates from the sensor kinase CckA and proceeds via the ChpT phosphotransferase to two regulatory substrates: the DNA-binding response regulator CtrA and the phospho-receiver protein CpdR. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), a REC signal receiver domain, and some contain PAS or PAS and GAF sensor domain(s).
Pssm-ID: 340396 [Multi-domain] Cd Length: 116 Bit Score: 69.33 E-value: 4.83e-14
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 794 YTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16919 47 YVCLEVSDTGSGMPAEVLRRAFEPFFTTKEVGKGTGLGLSMVYGFVKQSGGHLRIYSEPGVGTTVRIYLP 116
|
|
| HATPase_BceS-YxdK-YvcQ-like |
cd16948 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
758-863 |
7.08e-14 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis BceS, YxdK, and Bacillus thuringiensis YvcQ; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Bacillus subtilis BceS and Bacillus thuringiensis YvcQ, the HKs of the two-component regulatory system (TCSs) BceS-BceR and YvcQ-YvcP, repsectively, which are both involved in regulating bacitracin resistance. It also includes the HATPase domain of YxdK, the HK of YxdK-YxdJ TCS involved in sensing antimicrobial compounds.
Pssm-ID: 340424 [Multi-domain] Cd Length: 109 Bit Score: 68.47 E-value: 7.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 758 TDSVRLKQVVNNLINNAKKFT-VTGSITFgYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDS---FTQGAGLGLS 833
Cdd:cd16948 1 TDAKWLSFIIGQIVSNALKYSkQGGKIEI-YSETNEQGVVLSIKDFGIGIPEEDLPRVFDKGFTGENgrnFQESTGMGLY 79
|
90 100 110
....*....|....*....|....*....|
gi 2796428172 834 ICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16948 80 LVKKLCDKLGHKIDVESEVGEGTTFTITFP 109
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
766-863 |
2.04e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 66.93 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 766 VVNNLINNA-----------KKFTVTgsitfgyVTNREGYTTIFVEDTGSGISEDAQKHIFERFY--KEDSftqGAGLGL 832
Cdd:cd16915 4 IVGNLIDNAldalaatgapnKQVEVF-------LRDEGDDLVIEVRDTGPGIAPELRDKVFERGVstKGQG---ERGIGL 73
|
90 100 110
....*....|....*....|....*....|.
gi 2796428172 833 SICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16915 74 ALVRQSVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
620-855 |
4.91e-13 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 72.80 E-value: 4.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 620 QSIQRYKDTEEALIAARDRALQADKLKS--AFLANMSHEIRTPLNAI--VGFSdLLKDLDAFSPEEVKQFVETININCTL 695
Cdd:COG4192 405 TEIEERKRIEKNLRQTQDELIQAAKMAVvgQTMTSLAHELNQPLNAMsmYLFS-AKKALEQENYAQLPTSLDKIEGLIER 483
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 696 LLALINDILDLSRIESGTMDFkfgafnlAFIMQEVHESQRLSMPRDVELRIEIPEGEDKLVITDSVRLKQVVNNLINNAK 775
Cdd:COG4192 484 MDKIIKSLRQFSRKSDTPLQP-------VDLRQVIEQAWELVESRAKPQQITLHIPDDLMVQGDQVLLEQVLVNLLVNAL 556
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 776 KFTVTGSITFGYVTNREGYTTIFVEDTGSGIsEDAQKhIFERFYKedSFTQGAGLGLSICQTIVDRLHGSISVSSELGKG 855
Cdd:COG4192 557 DAVATQPQISVDLLSNAENLRVAISDNGNGW-PLVDK-LFTPFTT--TKEVGLGLGLSICRSIMQQFGGDLYLASTLERG 632
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
5.79e-13 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 65.55 E-value: 5.79e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTvTGSITFGYVTNREgYTTIFVEDTGSGISEDAQKHIFERFYKEDSF--TQGAGLGLSICQTIVD 840
Cdd:cd16950 1 LKRVLSNLVDNALRYG-GGWVEVSSDGEGN-RTRIQVLDNGPGIAPEEVDELFQPFYRGDNArgTSGTGLGLAIVQRISD 78
|
90 100
....*....|....*....|...
gi 2796428172 841 RLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16950 79 AHGGSLTLANRAGGGLCARIELP 101
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
649-863 |
4.83e-12 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 69.77 E-value: 4.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 649 FLANMS----HEIRTPLnAIVGFS-DLLKDLDAfsPEEVKQFVETININCTLLLALINDILDLSRIESGTMDFKFGAFNL 723
Cdd:TIGR03785 484 YLENMSsrlsHELRTPV-AVVRSSlENLELQAL--EQEKQKYLERAREGTERLSMILNNMSEATRLEQAIQSAEVEDFDL 560
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 724 AFIMQEVHES-QRLSMPRDVELRIEipegEDKLVITDSVRL-KQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVED 801
Cdd:TIGR03785 561 SEVLSGCMQGyQMTYPPQRFELNIP----ETPLVMRGSPELiAQMLDKLVDNAREFSPEDGLIEVGLSQNKSHALLTVSN 636
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2796428172 802 TGSGISEDAQKHIFerfykeDSF----TQGA------GLGLSICQTIVDRLHGSISVSSEL-GKGTRFEVVIP 863
Cdd:TIGR03785 637 EGPPLPEDMGEQLF------DSMvsvrDQGAqdqphlGLGLYIVRLIADFHQGRIQAENRQqNDGVVFRISLP 703
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
649-849 |
2.10e-11 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 66.98 E-value: 2.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 649 FLANMSHEIRTPLNAIVGFSD---LLKDLDAFSPEEVKQFVETINiNCTlllALINDILDLSRIESGTMDFKFGAFNLAF 725
Cdd:PRK10337 240 FTSDAAHELRSPLAALKVQTEvaqLSDDDPQARKKALLQLHAGID-RAT---RLVDQLLTLSRLDSLDNLQDVAEIPLED 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 726 IMQE-VHESQRLSMPRDVELRIEIPegeDKLVIT--DSVRLKQVVNNLINNAKKFTVTGSITFGYVTNRegytTIFVEDT 802
Cdd:PRK10337 316 LLQSaVMDIYHTAQQAGIDVRLTLN---AHPVIRtgQPLLLSLLVRNLLDNAIRYSPQGSVVDVTLNAR----NFTVRDN 388
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2796428172 803 GSGISEDAQKHIFERFYKEDSFTQ-GAGLGLSICQTIVdRLHGsISVS 849
Cdd:PRK10337 389 GPGVTPEALARIGERFYRPPGQEAtGSGLGLSIVRRIA-KLHG-MNVS 434
|
|
| PRK13560 |
PRK13560 |
hypothetical protein; Provisional |
374-863 |
2.19e-11 |
|
hypothetical protein; Provisional
Pssm-ID: 106506 [Multi-domain] Cd Length: 807 Bit Score: 67.78 E-value: 2.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 374 LVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQ-MLGLSSETYTSRFYEGQ--------MAGSIFRIYMNGENILQ 444
Cdd:PRK13560 327 LLEKEDMLRAIIEAAPIAAIGLDADGNICFVNNNAAErMLGWSAAEVMGKPLPGMdpelneefWCGDFQEWYPDGRPMAF 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 445 DLLKKVRTGKSPIPIPEKAFMQENHQGTYFPVSGEVVPIFANE-KMTGMAIVCRNISEE---EMQRRFFNMAVEESSIYP 520
Cdd:PRK13560 407 DACPMAKTIKGGKIFDGQEVLIEREDDGPADCSAYAEPLHDADgNIIGAIALLVDITERkqvEEQLLLANLIVENSPLVL 486
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 521 WQYNMRMNrfhFPGGLLRR----FGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEINSRMSFRLKSVDGSYEW 596
Cdd:PRK13560 487 FRWKAEEG---WPVELVSKnitqFGYEPDEFISGKRMFAAIIHPADLEQVAAEVAEFAAQGVDRFEQEYRILGKGGAVCW 563
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 597 WEFRSTA-YDSLTVDTPYMvlGVCQSIQRYKDTEEALIAARDRalqadklKSAFLANMSHEIRTPLNAIvgfSDLLkDLD 675
Cdd:PRK13560 564 IDDQSAAeRDEEGQISHFE--GIVIDISERKHAEEKIKAALTE-------KEVLLKEIHHRVKNNLQII---SSLL-DLQ 630
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 676 AFS---PEEVKQFVETININCTLllALINDILDLSRiesgtmdfkfgafNLAFI-----MQEV--HESQRLSMPRDVeLR 745
Cdd:PRK13560 631 AEKlhdEEAKCAFAESQDRICAM--ALAHEKLYQSE-------------DLADIdfldyIESLtaHLKNSFAIDFGR-ID 694
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 746 IEIPEGEDKLVITDSVRLKQVVNNLINNAKKF----TVTGSITFGYVTNREGYTTIFVEDTGSGISEDAqkhiferfyke 821
Cdd:PRK13560 695 CKIDADDGCLDIDKAIPCGLIISELLSNALKHafpdGAAGNIKVEIREQGDGMVNLCVADDGIGLPAGF----------- 763
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 2796428172 822 dSFTQGAGLGLSICQTIVDRLHGSISVSSElgKGTRFEVVIP 863
Cdd:PRK13560 764 -DFRAAETLGLQLVCALVKQLDGEIALDSR--GGARFNIRFP 802
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
2.91e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 60.91 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKF---TVTGSITFgyvtnREGYTTIFVEDTGSGISEDAQKHIFERFYKEDS----FTQGAGLGLSIC 835
Cdd:cd16939 1 MARALDNLLRNALRYahrTVRIALLV-----SGGRLTLIVEDDGPGIPAAARERVFEPFVRLDPsrdrATGGFGLGLAIV 75
|
90 100
....*....|....*....|....*....
gi 2796428172 836 QTIVDRLHGSISV-SSELGkGTRFEVVIP 863
Cdd:cd16939 76 HRVALWHGGHVECdDSELG-GACFRLTWP 103
|
|
| HATPase_VanS-like |
cd16923 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
4.46e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Enterococcus faecium VanS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Enterococcus faecium VanS HK of the VanS-VanR two-component regulatory system (TCS) which activates the transcription of vanH, vanA and vanX vancomycin resistance genes. It also contains Ecoli YedV and PcoS, probable members of YedW-YedV TCS and PcoS-PcoR TCS, repectively. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); most also have a HAMP sensor domain.
Pssm-ID: 340400 [Multi-domain] Cd Length: 102 Bit Score: 60.09 E-value: 4.46e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSF--TQGAGLGLSICQTIVD 840
Cdd:cd16923 1 LQRVFSNLLSNAIKYSPENTRIYITSFLTDDVVNIMFKNPSSHPLDFKLEKLFERFYRGDNSrnTEGAGLGLSIAKAIIE 80
|
90 100
....*....|....*....|...
gi 2796428172 841 RLHGSISVSSElGKGTRFEVVIP 863
Cdd:cd16923 81 LHGGSASAEYD-DNHDLFKVRLP 102
|
|
| HATPase_CpxA-like |
cd16949 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
7.45e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CpxA; This family includes the histidine kinase-like ATPase (HATPase) domains of two-component sensor histidine kinase (HKs) similar to Escherichia coli CpxA, HK of the CpxA-CpxR two-component regulatory system (TCS) which may function in acid stress and in cell wall stability. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a CpxA family periplasmic domain.
Pssm-ID: 340425 [Multi-domain] Cd Length: 104 Bit Score: 59.65 E-value: 7.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKKFTVTGSITFGYVTNREgyTTIFVEDTGSGISEDAQKHIFERFYKEDSF----TQGAGLGLSICQTI 838
Cdd:cd16949 1 LARALENVLRNALRYSPSKILLDISQDGDQ--WTITITDDGPGVPEDQLEQIFLPFYRVDSArdreSGGTGLGLAIAERA 78
|
90 100
....*....|....*....|....*
gi 2796428172 839 VDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16949 79 IEQHGGKIKASNRKPGGLRVRIWLP 103
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
759-849 |
9.53e-11 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 59.40 E-value: 9.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 759 DSVRLKQVVNNLINNAKKFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKED-SFTQGA--GLGLSIC 835
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEYLYFEIWDNGHGFSEQDLKKALELFYRDDtSRRSGGhyGMGLYIA 80
|
90
....*....|....
gi 2796428172 836 QTIVDRLHGSISVS 849
Cdd:cd16975 81 KNLVEKHGGSLIIE 94
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
632-867 |
1.28e-10 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 63.83 E-value: 1.28e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 632 LIAARDRALQADKLksaFLANMSHEIRTPLNAIVGFSDLLKDLdafSPEEVKQFVETINinctLLLALINDILDLSRIES 711
Cdd:PRK10755 126 LVSRLTSTLDQERL---FTADVAHELRTPLAGIRLHLELLEKQ---HHIDVAPLIARLD----QMMHTVEQLLQLARAGQ 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 712 gtmDFKFGAFNLAFIMQEVHESQRLSMPRDVELR---IEIPEGEDKLVIT-DSVRLKQVVNNLINNAKKFTVTGS-ITFg 786
Cdd:PRK10755 196 ---SFSSGHYQTVKLLEDVILPSQDELSEMLEQRqqtLLLPESAADITVQgDATLLRLLLRNLVENAHRYSPEGStITI- 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 787 YVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTIVDRLHGSISVSSEL-GKGTRFEVVIPDA 865
Cdd:PRK10755 272 KLSQEDGGAVLAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQLHHGQFFLQNRQeRSGTRAWVWLPKA 351
|
..
gi 2796428172 866 NE 867
Cdd:PRK10755 352 QN 353
|
|
| HATPase_CreC-like |
cd16945 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
759-844 |
1.40e-10 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli CreC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli CreC of the CreC-CreB two-component regulatory system (TCS) involved in catabolic regulation. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and accessory sensory domain(s) such as HAMP, CACHE or PAS.
Pssm-ID: 340421 [Multi-domain] Cd Length: 106 Bit Score: 59.01 E-value: 1.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 759 DSVRLKQVVNNLINNAKKFT-VTGSITFGYVTNREGyTTIFVEDTGSGISEDAQKHIFERFY---KEDSFTQGAGLGLSI 834
Cdd:cd16945 1 DPFLLRQAINNLLDNAIDFSpEGGLIALQLEADTEG-IELLVFDEGSGIPDYALNRVFERFYslpRPHSGQKSTGLGLAF 79
|
90
....*....|
gi 2796428172 835 CQTIVdRLHG 844
Cdd:cd16945 80 VQEVA-QLHG 88
|
|
| PRK10815 |
PRK10815 |
two-component system sensor histidine kinase PhoQ; |
765-861 |
6.69e-10 |
|
two-component system sensor histidine kinase PhoQ;
Pssm-ID: 182754 [Multi-domain] Cd Length: 485 Bit Score: 62.34 E-value: 6.69e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 765 QVVNNLINNAKKFTvtgsITFGYVTNREG--YTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTIVDRL 842
Cdd:PRK10815 381 EVMGNVLDNACKYC----LEFVEISARQTdeHLHIVVEDDGPGIPESKRELIFDRGQRADTLRPGQGLGLSVAREITEQY 456
|
90 100
....*....|....*....|
gi 2796428172 843 HGSISVS-SELGkGTRFEVV 861
Cdd:PRK10815 457 EGKISAGdSPLG-GARMEVI 475
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
650-863 |
9.32e-10 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 61.87 E-value: 9.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 650 LANMSHEIRTPLNAIVGFSDLLKDLDAFSPEevkqfVETININCTLLLALINDILDLSRiesgtmdfkfgafnlafiMQE 729
Cdd:PRK09470 247 LSDISHELRTPLTRLQLATALLRRRQGESKE-----LERIETEAQRLDSMINDLLVLSR------------------NQQ 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 730 VHESQRLSMPRDvELRIEIPE---------GEDKLVITDSVR---------LKQVVNNLINNAKKFTVTgSITFGYVTNR 791
Cdd:PRK09470 304 KNHLERETFKAN-SLWSEVLEdakfeaeqmGKSLTVSAPPGPwpingnpnaLASALENIVRNALRYSHT-KIEVAFSVDK 381
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796428172 792 EGyTTIFVEDTGSGISEDAQKHIFERFYK----EDSFTQGAGLGLSICQTIVDRLHGSISVS-SELGkGTRFEVVIP 863
Cdd:PRK09470 382 DG-LTITVDDDGPGVPEEEREQIFRPFYRvdeaRDRESGGTGLGLAIVENAIQQHRGWVKAEdSPLG-GLRLTIWLP 456
|
|
| COG3920 |
COG3920 |
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction ... |
341-866 |
8.17e-09 |
|
Two-component sensor histidine kinase, HisKA and HATPase domains [Signal transduction mechanisms];
Pssm-ID: 443125 [Multi-domain] Cd Length: 495 Bit Score: 59.15 E-value: 8.17e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 341 GALVLLVAWLFRANRRESRKRIHAQTRLLIQHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSETYT 420
Cdd:COG3920 1 LLLALLLLLLLALAALLLLAALLLLAAALLLALLALLLLALLLLALLLASALLALLALSAAALAAALAVALAAAVGAAAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 421 SRFYEGQMAGSIFRIYMNGENILQDLLKKVRTGKSPIPIPEKAFMQENHQGTYFPVSGEVVPIFANEKMTGMAIVCRNIS 500
Cdd:COG3920 81 LLALLVLLLLLLLAAAALALALLLAALAGLLLLAALLLLRLVALLAALALLALLLLLLLLLAILALAELAVALAELAAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 501 EEEMQRRFFNMAVEESSIYPWQYNMRMNRFHFPGGLLRRFGYIGDTDLLTRDEMDALIHPEDLPHTRRNFDAILLGNEIN 580
Cdd:COG3920 161 LLLAEELAALRLAAAALLLLLAALLDLGLALAALAAAALLALLLALELLLALLLLLLLLLALLLVLLAALLRLRAAVLEE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 581 SRMSFRLKSVDgsyeWWEFRSTAYDSLTVDTPYMVLGVCQSIQRYKDTEEALIAARDRalqadklKSAFLANMSHEIRtp 660
Cdd:COG3920 241 LERRRRARGLG----RLLLLLLLLLLLLRALLLLAAGIRLVITERKRAEEELEASLEE-------KELLLRELHHRVK-- 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 661 lN--AIVgfSDLLK-DLDAFSPEEVKQFVETIN--INCtllLALINDILDLSRiESGTMDFKfgafnlAFIMQEVHESQR 735
Cdd:COG3920 308 -NnlQVV--SSLLRlQARRADDPEAREALEESQnrIQA---LALVHELLYQSE-DWEGVDLR------DYLRELLEPLRD 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 736 LSMPRDVELRIEIPEGEdkLVITDSVRLKQVVNNLINNAKKF----TVTGSITFGyVTNREGYTTIFVEDTGSGISEDAq 811
Cdd:COG3920 375 SYGGRGIRIELDGPDVE--LPADAAVPLGLILNELVTNALKHaflsGEGGRIRVS-WRREDGRLRLTVSDNGVGLPEDV- 450
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*
gi 2796428172 812 khiferfykedSFTQGAGLGLSICQTIVDRLHGSISVSSElgKGTRFEVVIPDAN 866
Cdd:COG3920 451 -----------DPPARKGLGLRLIRALVRQLGGTLELDRP--EGTRVRITFPLAE 492
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-860 |
1.25e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 53.23 E-value: 1.25e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAkkFTVTGSITFGYVT---NRE-GYTTIFVEDTGSGISEDAQKHIFERFYKEDSFTQGAGLGLSICQTI 838
Cdd:cd16976 1 IQQVLMNLLQNA--LDAMGKVENPRIRiaaRRLgGRLVLVVRDNGPGIAEEHLSRVFDPFFTTKPVGKGTGLGLSISYGI 78
|
90 100
....*....|....*....|..
gi 2796428172 839 VDRLHGSISVSSELGKGTRFEV 860
Cdd:cd16976 79 VEEHGGRLSVANEEGAGARFTF 100
|
|
| HATPase_Glnl-NtrB-like |
cd16918 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
763-863 |
2.52e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli GlnL (synonyms NtrB and NRII); This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs), similar to Escherichia coli GlnL/NtrB/NRII HK of the two-component regulatory system (TCS) GlnL/GlnG (NtrB-NtrC, or NRII-NRI), which regulates the transcription of genes encoding metabolic enzymes and permeases in response to carbon and nitrogen status in E. coli and related bacteria. Also included in this family are Rhodobacter capsulatus NtrB, Azospirillum brasilense NtrB, Vibrio alginolyticus NtrB, Rhizobium leguminosarum biovar phaseoli NtrB, and Herbaspirillum seropedicae NtrB. Escherichia coli GlnL/NtrB/NRII is both a kinase and a phosphatase, catalyzing the phosphorylation and dephosphorylation of GlnG/NtrC/NRI. The kinase and phosphatase activities of GlnL/NtrB/NRII are regulated by the PII signal transduction protein, which on binding to GlnL/NtrB/NRII, inhibits the kinase activity of GlnL/NtrB/NRII and activates the GlnL/NtrB/NRII phosphatase activity. Proteins having this HATPase domain also have a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also contain PAS sensor domain(s).
Pssm-ID: 340395 [Multi-domain] Cd Length: 109 Bit Score: 52.79 E-value: 2.52e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 763 LKQVVNNLINNAKK--------FTVTGSITFGYVTNREGY---TTIFVEDTGSGISEDAQKHIFERFYKedSFTQGAGLG 831
Cdd:cd16918 1 LIQVFLNLVRNAAQalagsggeIILRTRTQRQVTLGHPRHrlaLRVSVIDNGPGIPPDLQDTIFYPMVS--GRENGTGLG 78
|
90 100 110
....*....|....*....|....*....|..
gi 2796428172 832 LSICQTIVDRLHGSISVSSELGKgTRFEVVIP 863
Cdd:cd16918 79 LAIAQNIVSQHGGVIECDSQPGH-TVFSVSLP 109
|
|
| PRK10618 |
PRK10618 |
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional |
624-863 |
1.91e-07 |
|
phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional
Pssm-ID: 236726 [Multi-domain] Cd Length: 894 Bit Score: 54.94 E-value: 1.91e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 624 RYKDtEEALIAAR--------DRALQADKlksAFLANMSHEIRTPLNAIVGFSDLLKDLD--AFSPEEVKQFVETINInc 693
Cdd:PRK10618 424 RDQD-REVLVNKKlqqaqreyEKNQQARK---AFLQNIGDELKQPLQSLAQLAAQLRQTSdeEQQQPELDQLAEQSDV-- 497
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 694 tlLLALINDILDLSRIESGTMDFKFGAFNLAFIMQEVHESQRLSMPRD-VELRIEIPEGEDKLVITDSVRLKQVVNNLIN 772
Cdd:PRK10618 498 --LVRLVDNIQLLNMLETQDWKPEQELFSLQDLIDEVLPEVLPAIKRKgLQLLIHNHLKAEQLRIGDRDALRKILLLLLN 575
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 773 NAKKFTVTGSITF--GYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKE---DSFTQGAGLGLSICQTIVDRLHGSIS 847
Cdd:PRK10618 576 YAITTTAYGKITLevDQDESSPDRLTIRILDTGAGVSIKELDNLHFPFLNQtqgDRYGKASGLTFFLCNQLCRKLGGHLT 655
|
250
....*....|....*.
gi 2796428172 848 VSSELGKGTRFEVVIP 863
Cdd:PRK10618 656 IKSREGLGTRYSIHLK 671
|
|
| PAS |
COG2202 |
PAS domain [Signal transduction mechanisms]; |
367-501 |
3.90e-07 |
|
PAS domain [Signal transduction mechanisms];
Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 52.33 E-value: 3.90e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 367 RLLIQHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSEtytsrfyegQMAGSIFRIYM---NGENIL 443
Cdd:COG2202 125 RKRAEEALRESEERLRLLVENAPDGIFVLDLDGRILYVNPAAEELLGYSPE---------ELLGKSLLDLLhpeDRERLL 195
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2796428172 444 QDLLKKVRTGKSPIPIPekaFMQENHQGTYFPVSGEVVPIFANEKMTGMAIVCRNISE 501
Cdd:COG2202 196 ELLRRLLEGGRESYELE---LRLKDGDGRWVWVEASAVPLRDGGEVIGVLGIVRDITE 250
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
759-863 |
4.25e-07 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 49.07 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 759 DSVRLKQVVNNLINNAK-----KFTVTGSITFGYVTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDSftQGAGLGLS 833
Cdd:cd16944 1 DTTQISQVLTNILKNAAeaiegRPSDVGEVRIRVEADQDGRIVLIVCDNGKGFPREMRHRATEPYVTTRP--KGTGLGLA 78
|
90 100 110
....*....|....*....|....*....|
gi 2796428172 834 ICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16944 79 IVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| sensory_box |
TIGR00229 |
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain ... |
384-507 |
5.25e-07 |
|
PAS domain S-box; The PAS domain was previously described. This sensory box, or S-box domain occupies the central portion of the PAS domain but is more widely distributed. It is often tandemly repeated. Known prosthetic groups bound in the S-box domain include heme in the oxygen sensor FixL, FAD in the redox potential sensor NifL, and a 4-hydroxycinnamyl chromophore in photoactive yellow protein. Proteins containing the domain often contain other regulatory domains such as response regulator or sensor histidine kinase domains. Other S-box proteins include phytochromes and the aryl hydrocarbon receptor nuclear translocator. [Regulatory functions, Small molecule interactions]
Pssm-ID: 272971 [Multi-domain] Cd Length: 124 Bit Score: 49.21 E-value: 5.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 384 IFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSEtytsrfyegQMAGSIFRIYMNGENILQDLLKKVRTGKSPIPIPEKA 463
Cdd:TIGR00229 8 IFESSPDAIIVIDLEGNILYVNPAFEEIFGYSAE---------ELIGRNVLELIPEEDREEVRERIERRLEGEPEPVSEE 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2796428172 464 FMQENHQGTYFPVSGEVVPIFANEKMTGMAIVCRNISEEEMQRR 507
Cdd:TIGR00229 79 RRVRRKDGSEIWVEVSVSPIRTNGGELGVVGIVRDITERKEAEE 122
|
|
| RocR |
COG3829 |
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis ... |
371-517 |
5.11e-06 |
|
RocR-type transcriptional regulator, contains PAS, AAA-type ATPase, and DNA-binding Fis domains [Transcription, Signal transduction mechanisms];
Pssm-ID: 443041 [Multi-domain] Cd Length: 448 Bit Score: 49.77 E-value: 5.11e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 371 QHRLVEQRDEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSETYTSRfyegqmagSIFRIYMNGenilqDLLKKV 450
Cdd:COG3829 3 ELELKELEEELEAILDSLDDGIIVVDADGRITYVNRAAERILGLPREEVIGK--------NVTELIPNS-----PLLEVL 69
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2796428172 451 RTGKspipiPEKAFMQeNHQGTYFPVSGEVVPIFANEKMTGMAIVCRNISE-EEMQRRFFNMAVEESS 517
Cdd:COG3829 70 KTGK-----PVTGVIQ-KTGGKGKTVIVTAIPIFEDGEVIGAVETFRDITElKRLERKLREEELERGL 131
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
788-863 |
2.57e-05 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 47.71 E-value: 2.57e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2796428172 788 VTNREGYTTIFVEDTGSGISEDAQKHIFERFYKEDsftQGAGLGLSICQTIVDRLHG---SISVSSELGKGTRFEVVIP 863
Cdd:COG2972 366 IRKEGDRLVITVEDNGVGMPEEKLEKLLEELSSKG---EGRGIGLRNVRERLKLYYGeeyGLEIESEPGEGTTVTIRIP 441
|
|
| CheA |
COG0643 |
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms]; |
827-863 |
4.45e-05 |
|
Chemotaxis protein histidine kinase CheA [Signal transduction mechanisms];
Pssm-ID: 440408 [Multi-domain] Cd Length: 563 Bit Score: 47.10 E-value: 4.45e-05
10 20 30
....*....|....*....|....*....|....*..
gi 2796428172 827 GAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG0643 381 GRGVGMDVVKTNIEALGGTIEIESEPGKGTTFTLRLP 417
|
|
| HATPase_CheA-like |
cd16916 |
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some ... |
827-863 |
6.96e-05 |
|
Histidine kinase-like ATPase domain of the chemotaxis protein histidine kinase CheA, and some hybrid sensor histidine kinases; This family includes the cytoplasmic histidine kinase (HK) CheA, a transmembrane receptor which, together with cytoplasmic adaptor protein (CheW), forms the lattice at the core of the chemosensory array that controls the cellular chemotaxis of motile bacteria and archaea. CheA forms a two-component signal transduction system (TCS) with the response regulator CheY. Proteins having this CheA-like HATPase domain generally also have a histidine-phosphotransfer domain, a histidine kinase homodimeric domain, and a regulatory domain; some are hybrid sensor histidine kinases as they contain a REC signal receiver domain.
Pssm-ID: 340393 [Multi-domain] Cd Length: 178 Bit Score: 44.50 E-value: 6.96e-05
10 20 30
....*....|....*....|....*....|....*..
gi 2796428172 827 GAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:cd16916 142 GRGVGMDVVKRSIESLGGTIEVESEPGQGTTFTIRLP 178
|
|
| HATPase_UhpB-NarQ-NarX-like |
cd16917 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
765-863 |
9.25e-05 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli UhpB, NarQ and NarX, and Bacillus subtilis YdfH, YhcY and YfiJ; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli UhpB, a HK of the UhpB-UhpA TCS, NarQ and NarX, HKs of the NarQ-NarP and NarX-NarL TCSs, respectively, and Bacillus YdfH, YhcY and YfiJ HKs, of the YdfH-YdfI, YhcY-YhcZ and YfiJ-YfiK TCSs, respectively. In addition, it includes Bacillus YxjM, ComP, LiaS and DesK, HKs of the YxjM-YxjML, ComP-ComA, LiaS-LiaR, DesR-DesK TCSs, respectively. Proteins having this HATPase domain have a histidine kinase dimerization and phosphoacceptor domain; some have accessory domains such as GAF, HAMP, PAS and MASE sensor domains.
Pssm-ID: 340394 [Multi-domain] Cd Length: 87 Bit Score: 41.77 E-value: 9.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 765 QVVNNLINNAKKFTVTGSITFgYVTNREGYTTIFVEDTGSGISEDAQKhiferfykedsftQGAGLGLSICQTIVDRLHG 844
Cdd:cd16917 3 RIVQEALTNALKHAGASRVRV-TLSYTADELTLTVVDDGVGFDGPAPP-------------GGGGFGLLGMRERAELLGG 68
|
90
....*....|....*....
gi 2796428172 845 SISVSSELGKGTRFEVVIP 863
Cdd:cd16917 69 TLTIGSRPGGGTRVTARLP 87
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
661-863 |
9.68e-05 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 44.99 E-value: 9.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 661 LNAIVGFSDLLKDLDAFSPEEVKQFVETINincTLLLALINDILDLSRIESGTMDFKFGAfnLAFIMQEVHESQRLSmpr 740
Cdd:COG4585 69 LSAIKLQLEAARRLLDADPEAAREELEEIR---ELAREALAELRRLVRGLRPPALDDLGL--AAALEELAERLLRAA--- 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 741 DVELRIEIPEGEDKLviTDSVR--LKQVVNNLINNAKK------FTVTgsitfgyVTNREGYTTIFVEDTGSGISEDAQK 812
Cdd:COG4585 141 GIRVELDVDGDPDRL--PPEVElaLYRIVQEALTNALKhagatrVTVT-------LEVDDGELTLTVRDDGVGFDPEAAP 211
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2796428172 813 hiferfykedsftqGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:COG4585 212 --------------GGGLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLP 248
|
|
| PAS_3 |
pfam08447 |
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
534-604 |
1.19e-04 |
|
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya.
Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 41.56 E-value: 1.19e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2796428172 534 GGLLRRFGYiGDTDLL-TRDEMDALIHPEDLPHTRRNFDAILLGNEINSRMsFRLKSVDGSYEWWEFRSTAY 604
Cdd:pfam08447 6 PRFEEILGY-TPEELLgKGESWLDLVHPDDRERVREALWEALKGGEPYSGE-YRIRRKDGEYRWVEARARPI 75
|
|
| HATPase_ETR2_ERS2-EIN4-like |
cd16938 |
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related ... |
755-862 |
1.39e-04 |
|
Histidine kinase-like ATPase domain of Arabidopsis thaliana ETR2, ERS2, and EIN4, and related domains; This family includes the histidine kinase-like ATPase domains (HATPase) of three out of the five receptors that recognize the plant hormone ethylene in Arabidopsis thaliana. These three proteins have been classified as belonging to subfamily 2: ETR2, ERS2, and EIN4. They lack most of the motifs characteristic of histidine kinases, and EIN4 is the only one in this group containing the conserved histidine that is phosphorylated in two-component and phosphorelay systems. This family also includes the HATPase domains of Escherichia coli RcsD phosphotransferase which is a component of the Rcs-signaling system, a complex multistep phosphorelay involving five proteins, and is involved in many transcriptional networks such as cell division, biofilm formation, and virulence, among others. Also included is Schizosaccharomyces pombe Mak3 (Phk1) which participates in a multi-step two-component related system which regulates H2O2-induced activation of the Sty1 stress-activated protein kinase pathway. Most proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a GAF sensor domain; most are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340415 [Multi-domain] Cd Length: 133 Bit Score: 42.45 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 755 LVITDSVRLKQVVNNLINNAKKFTVT-GSITF-------------------------GYVTNRegyTTIFVEDTGSGISE 808
Cdd:cd16938 4 VVVGDERRVFQVLLHMLGNLLKMRNGgGNITFrvfleggsedrsdrdwgpwrpsmsdESVEIR---FEVEINDSGSPSIE 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2796428172 809 DAQ-KHIFERFYKEDSftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVI 862
Cdd:cd16938 81 SASmRNSLNRRYNLSE--LGEHLSFSICKQLVQLMGGNIWIVPGSGLGTTMSLLL 133
|
|
| glnL |
PRK11073 |
nitrogen regulation protein NR(II); |
653-863 |
1.91e-04 |
|
nitrogen regulation protein NR(II);
Pssm-ID: 182947 [Multi-domain] Cd Length: 348 Bit Score: 44.69 E-value: 1.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 653 MSHEIRTPLNAIVGFSDLLKDldAFSPEEVKQFVETININCTLLLALINDILDLSRIESGTMDfkfgafNLAFIMQEVHE 732
Cdd:PRK11073 137 LAHEIKNPLGGLRGAAQLLSK--ALPDPALTEYTKVIIEQADRLRNLVDRLLGPQRPGTHVTE------SIHKVAERVVQ 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2796428172 733 SQRLSMPRDVELRIE----IPEgedklVITDSVRLKQVVNNLINNAKKFTVT--GSIT------FGYVTNREGY---TTI 797
Cdd:PRK11073 209 LVSLELPDNVRLIRDydpsLPE-----LAHDPDQIEQVLLNIVRNALQALGPegGTITlrtrtaFQLTLHGERYrlaARI 283
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2796428172 798 FVEDTGSGISEDAQKHIFerfYKEDSFTQGA-GLGLSICQTIVDRLHGSISVSSELGKgTRFEVVIP 863
Cdd:PRK11073 284 DIEDNGPGIPPHLQDTLF---YPMVSGREGGtGLGLSIARNLIDQHSGKIEFTSWPGH-TEFSVYLP 346
|
|
| PRK13557 |
PRK13557 |
histidine kinase; Provisional |
794-863 |
5.63e-04 |
|
histidine kinase; Provisional
Pssm-ID: 237425 [Multi-domain] Cd Length: 540 Bit Score: 43.51 E-value: 5.63e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2796428172 794 YTTIFVEDTGSGISEDAQKHIFERFY--KEDSftQGAGLGLSICQTIVDRLHGSISVSSELGKGTRFEVVIP 863
Cdd:PRK13557 324 YVSIAVTDTGSGMPPEILARVMDPFFttKEEG--KGTGLGLSMVYGFAKQSGGAVRIYSEVGEGTTVRLYFP 393
|
|
| PAS |
smart00091 |
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
379-417 |
2.43e-03 |
|
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels.
Pssm-ID: 214512 Cd Length: 67 Bit Score: 37.38 E-value: 2.43e-03
10 20 30
....*....|....*....|....*....|....*....
gi 2796428172 379 DEFDNIFCSIRDGLITYDTDLRIHFVNRPLLQMLGLSSE 417
Cdd:smart00091 1 ERLRAILESLPDGIFVLDLDGRILYANPAAEELLGYSPE 39
|
|
| |
