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Conserved domains on  [gi|2706616322|ref|WP_338128003|]
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MULTISPECIES: WbuC family cupin fold metalloprotein [Bacteroides]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF6016 super family cl44896
Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin ...
 3-70 1.96e-42

Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin superfamily. These proteins contain 1 or 2 copies of the domain. This family of proteins is found in Proteobacteria and Bacteroidetes. Proteins in this family are typically between 132 and 162 amino acids in length.


The actual alignment was detected with superfamily member pfam19480:

Pssm-ID: 437312  Cd Length: 141  Bit Score: 135.88  E-value: 1.96e-42
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2706616322   3 FDKDFLGRLFEQAIESPRLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPNTSETVVCLCGKMDEV 70
Cdd:pfam19480   1 LNKEFLGKLFEQAMANPRLRQNFDLRTSEADTSQRMLNALLPGTVVPIHRHEDTTESVLCLCGKLDEV 68
 
Name Accession Description Interval E-value
DUF6016 pfam19480
Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin ...
 3-70 1.96e-42

Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin superfamily. These proteins contain 1 or 2 copies of the domain. This family of proteins is found in Proteobacteria and Bacteroidetes. Proteins in this family are typically between 132 and 162 amino acids in length.


Pssm-ID: 437312  Cd Length: 141  Bit Score: 135.88  E-value: 1.96e-42
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2706616322   3 FDKDFLGRLFEQAIESPRLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPNTSETVVCLCGKMDEV 70
Cdd:pfam19480   1 LNKEFLGKLFEQAMANPRLRQNFDLRTSEADTSQRMLNALLPGTVVPIHRHEDTTESVLCLCGKLDEV 68
cupin_WbuC TIGR04366
cupin fold metalloprotein, WbuC family; Members of this family show sequence similarity to ...
 3-89 3.52e-25

cupin fold metalloprotein, WbuC family; Members of this family show sequence similarity to cupin fold proteins (see pfam07883), including conserved His residues likely to serve as metal-binding ligands. Many members occur in bacterial O-antigen biosynthesis regions. Some members have acquired the gene symbol wbuC (e.g. Jarvis, et al, 2011), but publications using this term do not ascribe a function.


Pssm-ID: 275159  Cd Length: 132  Bit Score: 91.47  E-value: 3.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2706616322   3 FDKDFLGRLFEQAIESPRLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPNTSETVVCLCGKMDEV------NLIQik 76
Cdd:TIGR04366   2 IDQELLDELKAQAAKSPRLRANLNLHPSLDDPVQRMLIALEPGTYVRPHRHPHKSETFIVLEGELDVLlfdddgEVTE-- 79

                          90
                  ....*....|...
gi 2706616322  77 KFHLSVRCNAFGF 89
Cdd:TIGR04366  80 RVVLSPGGGTFGV 92
cupin_WbuC-like cd07005
Escherichia coli WbuC and related proteins, cupin domain; This family includes bacterial ...
 20-68 1.77e-13

Escherichia coli WbuC and related proteins, cupin domain; This family includes bacterial proteins homologous to WbuC, an Escherichia coli protein of unknown function with a cupin beta barrel fold. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380408  Cd Length: 114  Bit Score: 61.00  E-value: 1.77e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2706616322  20 RLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPN--TSETVVCLCGKMD 68
Cdd:cd07005     1 RRRAHLNLHESPDDPVQRMLNALQPGTYVRPHRHPDppKWELFVVLRGRIA 51
 
Name Accession Description Interval E-value
DUF6016 pfam19480
Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin ...
 3-70 1.96e-42

Domain of unknown function (DUF6016); This presumed domain is related to proteins in the Cupin superfamily. These proteins contain 1 or 2 copies of the domain. This family of proteins is found in Proteobacteria and Bacteroidetes. Proteins in this family are typically between 132 and 162 amino acids in length.


Pssm-ID: 437312  Cd Length: 141  Bit Score: 135.88  E-value: 1.96e-42
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2706616322   3 FDKDFLGRLFEQAIESPRLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPNTSETVVCLCGKMDEV 70
Cdd:pfam19480   1 LNKEFLGKLFEQAMANPRLRQNFDLRTSEADTSQRMLNALLPGTVVPIHRHEDTTESVLCLCGKLDEV 68
cupin_WbuC TIGR04366
cupin fold metalloprotein, WbuC family; Members of this family show sequence similarity to ...
 3-89 3.52e-25

cupin fold metalloprotein, WbuC family; Members of this family show sequence similarity to cupin fold proteins (see pfam07883), including conserved His residues likely to serve as metal-binding ligands. Many members occur in bacterial O-antigen biosynthesis regions. Some members have acquired the gene symbol wbuC (e.g. Jarvis, et al, 2011), but publications using this term do not ascribe a function.


Pssm-ID: 275159  Cd Length: 132  Bit Score: 91.47  E-value: 3.52e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2706616322   3 FDKDFLGRLFEQAIESPRLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPNTSETVVCLCGKMDEV------NLIQik 76
Cdd:TIGR04366   2 IDQELLDELKAQAAKSPRLRANLNLHPSLDDPVQRMLIALEPGTYVRPHRHPHKSETFIVLEGELDVLlfdddgEVTE-- 79

                          90
                  ....*....|...
gi 2706616322  77 KFHLSVRCNAFGF 89
Cdd:TIGR04366  80 RVVLSPGGGTFGV 92
cupin_WbuC-like cd07005
Escherichia coli WbuC and related proteins, cupin domain; This family includes bacterial ...
 20-68 1.77e-13

Escherichia coli WbuC and related proteins, cupin domain; This family includes bacterial proteins homologous to WbuC, an Escherichia coli protein of unknown function with a cupin beta barrel fold. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.


Pssm-ID: 380408  Cd Length: 114  Bit Score: 61.00  E-value: 1.77e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 2706616322  20 RLRQSFDLRTSSSDSSQRILNALFPGTVVPIHRHPN--TSETVVCLCGKMD 68
Cdd:cd07005     1 RRRAHLNLHESPDDPVQRMLNALQPGTYVRPHRHPDppKWELFVVLRGRIA 51
cupin_D-LI-like cd06998
sugar isomerase such as lyxose isomerase, cupin domain; This family includes D-lyxose ...
 42-67 2.50e-03

sugar isomerase such as lyxose isomerase, cupin domain; This family includes D-lyxose isomerase (D-LI; EC 5.3.1.15) homologous to YdaE from the sigma B regulon of Bacillus subtilis and to pathogenic Escherichia coli O157 z5688 D-lyxose isomerase (EcSI or Z5688), both having highly similar active sites. YdaE may have a synergistic role with ydaD, an NAD(P)-dependent alcohol dehydrogenase, in the adaptation to environment stresses, while EcSI has D-lyxose/D-mannose activity. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.


Pssm-ID: 380402  Cd Length: 100  Bit Score: 34.52  E-value: 2.50e-03
                          10        20
                  ....*....|....*....|....*.
gi 2706616322  42 LFPGTVVPIHRHPNTSETVVCLCGKM 67
Cdd:cd06998     6 VHPGQFCPPHHHGRKTESYEVRLGEM 31
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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