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Conserved domains on  [gi|2687330634|ref|WP_334095671|]
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FUSC family protein, partial [Helicobacter typhlonius]

Protein Classification

FUSC family protein( domain architecture ID 11441727)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
TCDB:  2.A.85

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
347-523 3.80e-24

Uncharacterized membrane protein YccC [Function unknown];


:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 102.78  E-value: 3.80e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 347 ASLKHNPAPFFYGVRYAVAIGCAMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGD 426
Cdd:COG1289    38 ANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLLLLALFPQ 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 427 SPLL-LWIFIPNLFLVVYFKTYPFMLWSMVLMLELVLMFALLDSNFIELILYRFGDILLGFLLAFCISKIIYPHYSANEL 505
Cdd:COG1289   118 PLLLlLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGPGVFDVALARVLDTLIGILIALLVSYLLWPRWARRRL 197
                         170
                  ....*....|....*...
gi 2687330634 506 IPQTTLCLESFAALVTSI 523
Cdd:COG1289   198 RARLARALRANARYLRAL 215
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
347-523 3.80e-24

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 102.78  E-value: 3.80e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 347 ASLKHNPAPFFYGVRYAVAIGCAMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGD 426
Cdd:COG1289    38 ANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLLLLALFPQ 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 427 SPLL-LWIFIPNLFLVVYFKTYPFMLWSMVLMLELVLMFALLDSNFIELILYRFGDILLGFLLAFCISKIIYPHYSANEL 505
Cdd:COG1289   118 PLLLlLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGPGVFDVALARVLDTLIGILIALLVSYLLWPRWARRRL 197
                         170
                  ....*....|....*...
gi 2687330634 506 IPQTTLCLESFAALVTSI 523
Cdd:COG1289   198 RARLARALRANARYLRAL 215
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
369-492 1.94e-16

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 75.74  E-value: 1.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 369 AMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGDSPLLLWIFIPNLFLVVYFKTYP 448
Cdd:pfam13515   2 AALIAELLGLPRGYWAPIAAAIVLQPTLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQLILVVALLGFLAEYLIGRN 81
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2687330634 449 FMLWSMVLMLELVLMFALLDS-NFIELILYRFGDILLGFLLAFCI 492
Cdd:pfam13515  82 YALAQVFVTPLALLLASLAGGgGPPELALLRILDTLIGALIALLV 126
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
347-523 3.80e-24

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 102.78  E-value: 3.80e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 347 ASLKHNPAPFFYGVRYAVAIGCAMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGD 426
Cdd:COG1289    38 ANLSPDSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQPSYGATLSRALQRILGTLLGALAGLLLLALFPQ 117
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 427 SPLL-LWIFIPNLFLVVYFKTYPFMLWSMVLMLELVLMFALLDSNFIELILYRFGDILLGFLLAFCISKIIYPHYSANEL 505
Cdd:COG1289   118 PLLLlLALALVLGLCFFALLTRSYAFALAGITAAVVLLFALLGPGVFDVALARVLDTLIGILIALLVSYLLWPRWARRRL 197
                         170
                  ....*....|....*...
gi 2687330634 506 IPQTTLCLESFAALVTSI 523
Cdd:COG1289   198 RARLARALRANARYLRAL 215
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
369-492 1.94e-16

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 75.74  E-value: 1.94e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 369 AMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGDSPLLLWIFIPNLFLVVYFKTYP 448
Cdd:pfam13515   2 AALIAELLGLPRGYWAPIAAAIVLQPTLGATLRRAVQRILGTVLGVLLGLLLLALLPGPLQLILVVALLGFLAEYLIGRN 81
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2687330634 449 FMLWSMVLMLELVLMFALLDS-NFIELILYRFGDILLGFLLAFCI 492
Cdd:pfam13515  82 YALAQVFVTPLALLLASLAGGgGPPELALLRILDTLIGALIALLV 126
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
347-524 3.09e-13

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 68.86  E-value: 3.09e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 347 ASLKHNPAPFFYGVRYAVAIGCAMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGD 426
Cdd:COG4129     2 KRRRALRRIGLRTLKTALAAALAWLIAELLGLPYPFFAAIAAVLCLQPTVGRSLRRALERILGVLIGALVGVLFFLLLGY 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 427 SPLLLWIF-IPNLFLVVYFKTYPfmLWSMVLMLELVLMFALLDSNFIELILYRFGDILLGFLLAFCISKIIYPHYSANEL 505
Cdd:COG4129    82 GPWQLGLAvLLAILLAVLLKLGE--GIVLAAVTALLVLLLGSPDDSLGYALNRLLDTLIGVGVALLVNLLLLPPDPERRL 159
                         170
                  ....*....|....*....
gi 2687330634 506 IPQTTLCLESFAALVTSIE 524
Cdd:COG4129   160 RRAAAELLEELADILRELL 178
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
358-523 1.19e-05

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 48.43  E-value: 1.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 358 YGVRYAVAIGCAMFFAQFFQINHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFIGLILGISLVLIFGDSPLL------L 431
Cdd:pfam04632   3 FALKTFLAAMLALYIALRLELPQPYWAMTTVFIVSQPLSGAVLSKSFYRLLGTLVGAAAAVLLVALFVQAPLLfllalaL 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 432 WIFIpNLF---LVVYFKTYPFML----WSMVLML-----ELVLMFAlldsnfieliLYRFGDILLGFLLAFCISKIIYPH 499
Cdd:pfam04632  83 WIGL-CLAlslLDRNFRSYAFVLagytAAIIGLPavadpEAIFDIA----------VARVSEISLGILCAALVSALVFPR 151
                         170       180
                  ....*....|....*....|....
gi 2687330634 500 YSANELIPQTTLCLESFAALVTSI 523
Cdd:pfam04632 152 SVGPALRARLRARLRDALRLAAAA 175
ArAE_1 pfam06081
Aromatic acid exporter family member 1; This family consists of bacterial proteins with three ...
363-490 1.02e-03

Aromatic acid exporter family member 1; This family consists of bacterial proteins with three transmembrane regions that are purported to be aromatic acid exporters.


Pssm-ID: 428756 [Multi-domain]  Cd Length: 141  Bit Score: 39.86  E-value: 1.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 363 AVAIGCAMFFAQFFQINhgAWIALGVISmmhqnIGSIKSAGKDSIFGSF-------IGLILGISLVLIFGDSP----LLL 431
Cdd:pfam06081  11 AIAVTLAIIIAELLGLP--YPVSAGIIA-----ILCIQPTKKRSLRTALarfqacvIGAIIAVVFFELFGYHPfsigLFL 83
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2687330634 432 WIFIPnlfLVVYFKTYPFMLWSMVLMLELVlmfaLLDSNFIELILYRFGDILLGFLLAF 490
Cdd:pfam06081  84 LLFIP---LTVKLKLEEGIVVSSVTVIHLL----ESKSISFFLILNELLLITIGIGVAL 135
ALMT pfam11744
Aluminium activated malate transporter;
379-558 3.99e-03

Aluminium activated malate transporter;


Pssm-ID: 432042 [Multi-domain]  Cd Length: 408  Bit Score: 40.03  E-value: 3.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 379 NHGAWIALGVISMMHQNIGSIKSAGKDSIFGSFI--GLILGISLV-LIFGDS--PLLLWIFIpnlFLVVYFKTYPFMLWS 453
Cdd:pfam11744  39 VNAVWAILTVVVVFEFSVGATLSKGLNRGLATLIagGLAFGVHHLaSSSGKIgePIVIGVSV---FIIGFAATFSRFHPA 115
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687330634 454 MVL-----MLELVLMFALL------DSNFIELILYRFGDILLGFLLAFCISKIIYPHYSANELIPQTTLCLESFAalvTS 522
Cdd:pfam11744 116 IKArydygFRVFLLTFCLVtvsgyrTDEFIETAHQRFYTIAIGAGICLIVSIFIFPIWAGEDLHKLVAKNFEKLA---NS 192
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 2687330634 523 IEDS-NGYtltcqnqLMRSLDELSSFIKESREEKKLY 558
Cdd:pfam11744 193 LEGCvNEY-------LEEVEYERSILEYEDDSDDSLY 222
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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