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Conserved domains on  [gi|2687072581|ref|WP_333956669|]
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MULTISPECIES: TonB-dependent receptor domain-containing protein [unclassified Pseudomonas]

Protein Classification

TonB-dependent receptor family protein( domain architecture ID 11469151)

TonB-dependent receptor family protein such as Escherichia coli Fe(3+) dicitrate transport protein FecA which is the outer membrane receptor protein in the Fe(3+) dicitrate transport system

Gene Ontology:  GO:0038023|GO:0009279|GO:0015343|GO:0015891
PubMed:  12948487
TCDB:  1.B.14

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
13-686 1.45e-135

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


:

Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 413.94  E-value: 1.45e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  13 LLAAFAATQPALAA-PAVELGQVLITDEeqndlSAASERLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGN 91
Cdd:COG4772     4 ALAAALLLAAAAAAeAATTLETVVVTGS-----RAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  92 DGI--KLSIRGSGINRApgahgSGVYTMFDGLPLTGP----GGTPYELfEPLWLSRAEVLRGANGFDQGALALGGAINYV 165
Cdd:COG4772    79 FGLrpNIGIRGLGPRRS-----RGITLLEDGIPIAPApygdPAAYYFP-DLERMERIEVLRGAAALRYGPQTVGGAINFV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 166 THTGYDAAPLQVRYEVGSRGYQHRHISSGQVLGNLDYYVALTDSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRY 245
Cdd:COG4772   153 TRTIPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQY 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 246 RETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQpgstwAGNKTTFYLDDDARLEAGLVYHDYPmdlREGPMRLKVA- 324
Cdd:COG4772   233 YDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDFS---RNWYIRQNTAd 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 325 --------------YTDVSGTLNYFRRDTLFGHESKTTIGWR----TTKHLPNSGASQFTRNGDVfgeRTRDFTYQGSDT 386
Cdd:COG4772   305 pntpglglrgnprgYRSYGIEPRLTHRFELGGVPHTLEVGLRyhreEEDRKQYVNTYGQGRSGAG---LRRDRRFSADAL 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 387 VLHVGNDLELVPDLWLTTGLAMIYTRRESDVTF-----PAEGGKVSMHDWdyAPRLGLRYDISPDLQVYGNLSRSVEPPH 461
Cdd:COG4772   382 AAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYstrtgGDDSGSNSYSEF--LPGLGLLYQLTDNLQLYANVSRGFEPPT 459

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 462 PWSLIwSSPTPNQPIEmqNQTATTLELGTRGES-ALGHWDLAWYYSQVRHELLAVEIVQGAPAKEFNASATVHQGVEAGL 540
Cdd:COG4772   460 FGDLA-YGNGGNPDLK--PEKSWNYELGTRGRIgNGLSAEVALFYIDYDNELGSCSAAGGDRSTFTNAGETRHQGLELAL 536

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 541 DSTLWERTGTGkLSLRQAYTFSDFHYRD--DDTFGDNRLPGIPMHYYQAELRYDWpNGFYAGVNTQMASKVQVDYANSYH 618
Cdd:COG4772   537 DYDLLKGGGLG-LPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVA 614

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2687072581 619 ------ADEYALLGARLGWDSPKqDWQTWLDLRNLTNKRYAATVTPGYNdagkDNARstPGEGFAVYAGVSYSF 686
Cdd:COG4772   615 dgsfgkIPSYTVLDLSASYDFGK-NLSLFAGVNNLFDKRYIASRAPNYA----AGIR--PGPPRTVYAGLRLKF 681
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
13-686 1.45e-135

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 413.94  E-value: 1.45e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  13 LLAAFAATQPALAA-PAVELGQVLITDEeqndlSAASERLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGN 91
Cdd:COG4772     4 ALAAALLLAAAAAAeAATTLETVVVTGS-----RAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  92 DGI--KLSIRGSGINRApgahgSGVYTMFDGLPLTGP----GGTPYELfEPLWLSRAEVLRGANGFDQGALALGGAINYV 165
Cdd:COG4772    79 FGLrpNIGIRGLGPRRS-----RGITLLEDGIPIAPApygdPAAYYFP-DLERMERIEVLRGAAALRYGPQTVGGAINFV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 166 THTGYDAAPLQVRYEVGSRGYQHRHISSGQVLGNLDYYVALTDSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRY 245
Cdd:COG4772   153 TRTIPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQY 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 246 RETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQpgstwAGNKTTFYLDDDARLEAGLVYHDYPmdlREGPMRLKVA- 324
Cdd:COG4772   233 YDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDFS---RNWYIRQNTAd 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 325 --------------YTDVSGTLNYFRRDTLFGHESKTTIGWR----TTKHLPNSGASQFTRNGDVfgeRTRDFTYQGSDT 386
Cdd:COG4772   305 pntpglglrgnprgYRSYGIEPRLTHRFELGGVPHTLEVGLRyhreEEDRKQYVNTYGQGRSGAG---LRRDRRFSADAL 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 387 VLHVGNDLELVPDLWLTTGLAMIYTRRESDVTF-----PAEGGKVSMHDWdyAPRLGLRYDISPDLQVYGNLSRSVEPPH 461
Cdd:COG4772   382 AAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYstrtgGDDSGSNSYSEF--LPGLGLLYQLTDNLQLYANVSRGFEPPT 459

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 462 PWSLIwSSPTPNQPIEmqNQTATTLELGTRGES-ALGHWDLAWYYSQVRHELLAVEIVQGAPAKEFNASATVHQGVEAGL 540
Cdd:COG4772   460 FGDLA-YGNGGNPDLK--PEKSWNYELGTRGRIgNGLSAEVALFYIDYDNELGSCSAAGGDRSTFTNAGETRHQGLELAL 536

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 541 DSTLWERTGTGkLSLRQAYTFSDFHYRD--DDTFGDNRLPGIPMHYYQAELRYDWpNGFYAGVNTQMASKVQVDYANSYH 618
Cdd:COG4772   537 DYDLLKGGGLG-LPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVA 614

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2687072581 619 ------ADEYALLGARLGWDSPKqDWQTWLDLRNLTNKRYAATVTPGYNdagkDNARstPGEGFAVYAGVSYSF 686
Cdd:COG4772   615 dgsfgkIPSYTVLDLSASYDFGK-NLSLFAGVNNLFDKRYIASRAPNYA----AGIR--PGPPRTVYAGLRLKF 681
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 62-686 6.46e-44

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 167.24  E-value: 6.46e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  62 DMQRVGQGRVAsnqDVLAYQPGVFAQSAGNDGIK-LSIRGSGINRapgahgsgVYTMFDGLPLTGPGGT--------PYE 132
Cdd:cd01347     9 DIEKQPATSLA---DLLRRIPGVSVTRGGGGGGStISIRGFGPDR--------TLVLVDGLPLASSNYGrgvdlntiPPE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 133 LFEplwlsRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGS------RGYQHRHISSGQVLGNLDYYVAL 206
Cdd:cd01347    78 LIE-----RVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdnsgssGGGGFDVSGALADDGAFGARLYG 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 207 TDSEYDGYQAHSSGSA------KGVAANVGYRFNPNleTRFYLRYRETENQLAGRLTKEQIKHHPRAANPAYLARDDSRP 280
Cdd:cd01347   153 AYRDGDGTIDGDGQADdsdeerYNVAGKLDWRPDDD--TRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 281 QPGSTWAGNKTTFYL------DDDARLEAGLVYHDYPMDLREGPMRLKVAYTDVSGTLNYFRrdtlfghESKTTIGWRTT 354
Cdd:cd01347   231 DWDYRDRYRKRASLGlehdlnDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYS-------SERDTTQLGFD 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 355 KHLPNSGASQFTRNGDVFGERTRDFTYQGSDTVLHVGNDLELVPDLWLTTGLAMIYTRRESDvTFPAEGGKVSMHDWDYA 434
Cdd:cd01347   304 AGLNAPFGTGPVAHTLTLGVEYRREELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSK-DTIAGGTTAKKSYSHWS 382

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 435 PRLGLRYDISPDLQVYGNLSRSVEPPHPW------SLIWSSPTPNQPIEMqnQTATTLELGTRGESALG-HWDLAWYYSQ 507
Cdd:cd01347   383 PSLGLVYKLTDGLSLYASYSQGFRAPSLGelygggSHGGTAAVGNPNLKP--EKSKQYELGLKYDPGDGlTLSAALFRID 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 508 VRHELLAVEIVQGAPAKEF--NASATVHQGVEAGLDSTLWERtgtgkLSLRQAYTFSDFHY-RDDDTFGDNRLPGIPMHY 584
Cdd:cd01347   461 IKNEIVSTPTNTGLGLVTVyvNGGKARIRGVELEASYDLTDG-----LGLTGSYTYTDTEVkRTDGATTGNRLPGIPKHT 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 585 YQAELRYDWP-NGFYAGVNTQMASKVQVDYANSYHADE---YALLGARLGWDsPKQDWQTWLDLRNLTNKRYAAtvtpgY 660
Cdd:cd01347   536 ANLGLDYELPdEGLTAGGGVRYRGKQYADTANGNNTVKvpgYTLVDLSASYQ-FTKNLTLRLGVNNLFDKDYYT-----S 609

                         650       660
                  ....*....|....*....|....*.
gi 2687072581 661 NDAGKDNARSTPGEGFAVYAGVSYSF 686
Cdd:cd01347   610 LSVRGSGLYGYYGPGRTYYLSVSYKF 635
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 211-685 7.46e-34

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 135.67  E-value: 7.46e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 211 YDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRYRETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQPGSTW---A 287
Cdd:pfam00593   2 WQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWlstL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 288 GNKTTFYLDDDARLEAGLVYHDYPMDLREGPMRLKVAYTDVSGTLNYFRRDTLFGHESKTTIG-WRTTKHLPNSGASQFT 366
Cdd:pfam00593  82 RLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLdYRRLDDDAYDPYDPAN 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 367 RNGDVFGERTRDftyqgsDTVLHVGNDLELVPDLWLTTGLAMIYTRRESDvTFPAEGGKVSMHDWDYAPRLGLRYDISPD 446
Cdd:pfam00593 162 PSSSSYSDTTTD------SYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGD-DGNGGGDNFSRSYSAFSPRLGLVYKPTDN 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 447 LQVYGNLSRSVEPPHPWSLIWSSPTPNQPIEMQN------QTATTLELGTRGESALGHWDLAWYYSQVRHELLAVEIVQG 520
Cdd:pfam00593 235 LSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGnpdlkpETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPG 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 521 APAKEF---NASATVHQGVEAGLDSTLWERTGTGKlslrqAYTFSDFHYRDDDTFGDNRLPGIPMHYYQAELRYDWPNGF 597
Cdd:pfam00593 315 LGGTVYtytNVGKARIRGVELELSGRLWGLGLSGG-----GYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDFPLGG 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 598 Y---AGVN-TQMASKVQVDYANSYHADEYALLGARLGWDsPKQDWQTWLDLRNLTNKRYAatvtpGYNDAGKDNARSTPG 673
Cdd:pfam00593 390 WgarLGARyVGSGERRYGDAANTFKTPGYTLVDLSAGYR-LNKNLTLRLGVNNLFDKYYK-----RYYSSGGGNLGGYPG 463

                         490
                  ....*....|..
gi 2687072581 674 EGFAVYAGVSYS 685
Cdd:pfam00593 464 PGRTFYLGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 53-686 9.10e-25

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 109.42  E-value: 9.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  53 EVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGNDGIK--LSIRGSGINrapgahGSGVYTMFDGLPLTGPGGtp 130
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFgnITIRGFGLE------VDIDNVYLDGVPLLSRGN-- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 131 YELFEPLWLSRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVLG---NLDYYVALT 207
Cdd:TIGR01783  73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGGPLGadgTFRGRLNGA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 208 DSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRYR-ETENQLAGRLTKEQIKHHPRAANPAYLARDDSRP------ 280
Cdd:TIGR01783 153 RQDGDSFYDGAGEETRLGATATDWQLDDRTLLRLGAYYQkERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNyddrey 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 281 ---------QPGSTWAGNKTTFYL---DDDARLEAGLVY---HDYPMDLREGPMRLKVaytdVSGTLNYFRRDTLFGHES 345
Cdd:TIGR01783 233 lsyglsleyQFNDVWTGKQNLRYSyfdTDSNQVQASGYSsdgGLFGRSLTVVNVKQDR----VQIDAGLDGEFETGPIEH 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 346 KTTIGWRTTKHLPNSGASQF-----TRNGDVFGERTRDFTYQGSDTVL--------HVGNDLELVPDLWLTTgLAMIYTR 412
Cdd:TIGR01783 309 DLLLGVSYGQRTTNRFNNTGypsdnIYSLTATSSARTDIGDSPKDRALssttkalnGVALQRILLADKWTLT-LGGRYDS 387

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 413 RESDVTFPAEGGKVSMHDWDYAPRLGLRYDISPDLQVYGNLSRSVEPPhpwsLIWSSPTPNQPIEMQNQTATTLELGTRG 492
Cdd:TIGR01783 388 VDVKSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG----GYYPKGAGNSGDILEPEKGKNYELGVRY 463

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 493 ESAlGHW--DLAWYYSQVRHELlaveiVQGAPAKEF--NASATVHQGVEAGLDSTLwertgTGKLSLRQAYTFSDFHYRD 568
Cdd:TIGR01783 464 DLG-DSLlaTAALFRITKDNQL-----VQDPVNGTFsvNAGKTRNRGVELEARGYL-----TPGLSLSAGYTYTDAEFTE 532

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 569 DD--TFGDNRLPGIPMHY------YQAelrYDWPNGFYAGVNTQMASKVQVDYANSYHADEYALLGARLGWDSPKQDWQT 640
Cdd:TIGR01783 533 DTngDTQGNTVPFVPKHTaslwasYAP---PVGDNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKKKNLT 609

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 2687072581 641 W-LDLRNLTNKRYaatVTPGYNDAGkdNARSTPGEGFAVYAGVSYSF 686
Cdd:TIGR01783 610 LaLNVNNLFDRDY---YTSGYRWGP--SAYIYPGAPRTVGLSVSYDF 651
PRK14050 PRK14050
TonB-dependent siderophore receptor;
45-165 2.68e-05

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 47.49  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  45 SAASERLREVPGASNLVDMQRVgQGRVASNQ--DVLAYQPGVFAQSAGNDGIK--LSIRGSGinrapgAHGSGVYtmFDG 120
Cdd:PRK14050   70 SKTDTPITEIPQSVSVVGRQEM-DDRGVTNKvdEALRYTPGVLSQPFGTDGDTdwFYIRGFD------ATQTGVF--LDG 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2687072581 121 LPL--TGPGGTpyeLFEPLWLSRAEVLRGANGFDQGALALGGAINYV 165
Cdd:PRK14050  141 LNLfsYGFGGF---QIDPFMLERVEVLKGPASVLYGGSNPGGIVNMV 184
 
Name Accession Description Interval E-value
FecA COG4772
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
13-686 1.45e-135

Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];


Pssm-ID: 443804 [Multi-domain]  Cd Length: 681  Bit Score: 413.94  E-value: 1.45e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  13 LLAAFAATQPALAA-PAVELGQVLITDEeqndlSAASERLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGN 91
Cdd:COG4772     4 ALAAALLLAAAAAAeAATTLETVVVTGS-----RAAEARLKDVPGSVSVVDREELENQAATSLREVLRRVPGVNVQEEDG 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  92 DGI--KLSIRGSGINRApgahgSGVYTMFDGLPLTGP----GGTPYELfEPLWLSRAEVLRGANGFDQGALALGGAINYV 165
Cdd:COG4772    79 FGLrpNIGIRGLGPRRS-----RGITLLEDGIPIAPApygdPAAYYFP-DLERMERIEVLRGAAALRYGPQTVGGAINFV 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 166 THTGYDAAPLQVRYEVGSRGYQHRHISSGQVLGNLDYYVALTDSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRY 245
Cdd:COG4772   153 TRTIPTAFGGELRVTGGSFGYRRTHASVGGTVGNFGYLVEYSRKRGDGFRDNSGFDINDFNAKLGYRLSDRQELTLKFQY 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 246 RETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQpgstwAGNKTTFYLDDDARLEAGLVYHDYPmdlREGPMRLKVA- 324
Cdd:COG4772   233 YDEDANTPGGLTDAQFDADPRQSYRPADQFDTRRTQ-----LSLRYEHQLSDNTTLTTTAYYNDFS---RNWYIRQNTAd 304

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 325 --------------YTDVSGTLNYFRRDTLFGHESKTTIGWR----TTKHLPNSGASQFTRNGDVfgeRTRDFTYQGSDT 386
Cdd:COG4772   305 pntpglglrgnprgYRSYGIEPRLTHRFELGGVPHTLEVGLRyhreEEDRKQYVNTYGQGRSGAG---LRRDRRFSADAL 381

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 387 VLHVGNDLELVPDLWLTTGLAMIYTRRESDVTF-----PAEGGKVSMHDWdyAPRLGLRYDISPDLQVYGNLSRSVEPPH 461
Cdd:COG4772   382 AAYAQNRFELTGRLTLTPGLRYEHIRRDRTDRYstrtgGDDSGSNSYSEF--LPGLGLLYQLTDNLQLYANVSRGFEPPT 459

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 462 PWSLIwSSPTPNQPIEmqNQTATTLELGTRGES-ALGHWDLAWYYSQVRHELLAVEIVQGAPAKEFNASATVHQGVEAGL 540
Cdd:COG4772   460 FGDLA-YGNGGNPDLK--PEKSWNYELGTRGRIgNGLSAEVALFYIDYDNELGSCSAAGGDRSTFTNAGETRHQGLELAL 536

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 541 DSTLWERTGTGkLSLRQAYTFSDFHYRD--DDTFGDNRLPGIPMHYYQAELRYDWpNGFYAGVNTQMASKVQVDYANSYH 618
Cdd:COG4772   537 DYDLLKGGGLG-LPLFAAYTYTDAEFTSdfGPVFAGNRLPYVPRHQLTAGLGYEH-GGWTANLNGRYVSEQFTDAANTVA 614

                         650       660       670       680       690       700       710
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2687072581 619 ------ADEYALLGARLGWDSPKqDWQTWLDLRNLTNKRYAATVTPGYNdagkDNARstPGEGFAVYAGVSYSF 686
Cdd:COG4772   615 dgsfgkIPSYTVLDLSASYDFGK-NLSLFAGVNNLFDKRYIASRAPNYA----AGIR--PGPPRTVYAGLRLKF 681
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
45-663 5.63e-86

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 283.26  E-value: 5.63e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  45 SAASERLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGNDGIKLSIRGSGinrapgAHGSGVYTMFDGLPLT 124
Cdd:COG1629     9 TRTDESLQDVPGSVSVISREQLEDQPATDLGDLLRRVPGVSVTSAGGGAGQISIRGFG------GGGNRVLVLVDGVPLN 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 125 GP--GGTPYELFEPLWLSRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVLGNLDY 202
Cdd:COG1629    83 DPsgGDGGLSYIDPEDIERVEVLRGPSSALYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRASLSLSGGNGKLAY 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 203 YVALTDSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRYRETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQP 282
Cdd:COG1629   163 RLSASYRDSDGYRDNSDSDRYNLRAKLGYQLGDDTRLTLSASYSDSDQDSPGYLTLAALRPRGAMDDGTNPYSNDTDDNT 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 283 GSTWAGNKTTFYLDDDARLEAGLVY---------HDYPMDLREGPMRLKVAYTDVSGTLNYFRRDTLFGHESKTTIGWRT 353
Cdd:COG1629   243 RDRYSLSLEYEHLGDGLKLSASAYYryddtdldsDFTPTPADGGTLEQTDFDNRTYGLELRLTYDLGFGGKHTLLVGLDY 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 354 TKHLPNSGASQFTRNGDVFGERTRDFTYQGSDTV--LHVGNDLELVPDLWLTTGLAMIYTRRESDVTFPAEGGKVSMHDW 431
Cdd:COG1629   323 QRQDLDGSGYPLDLGSGSLPTLTSGADDDGTTTSlaLYAQDTYKLTDKLTLTAGLRYDYVSYDVDDTVTGTDSASGSRSY 402

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 432 D-YAPRLGLRYDISPDLQVYGNLSRSVEPPHPWSLIWSSPTPNQP--IEMQNQTATTLELGTRGESALG--HWDLAWYYS 506
Cdd:COG1629   403 SaFSPSLGLTYQLSPNLSLYASYSRGFRAPTFGELYANGTDPYSVgnPDLKPETSTNYELGLRYRLLDGrlSLSLALFYS 482

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 507 QVRHELLAVEIVQ--GAPAKEFNASATVHQGVEAGLDSTLWERtgtgkLSLRQAYTFSDFHYRDDDT----FGDNRLPGI 580
Cdd:COG1629   483 DVDNEILSVPLPNdsGFSTYYTNAGKARSYGVELELSYQLTPG-----LSLNASYSYTDAKFDDDTDgsadLDGNRLPGV 557

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 581 PMHYYQAELRYDWPNGFYAGVNTQMASKVQVDYANSYHADE-YALLGARLGWDsPKQDWQTWLDLRNLTNKRYAATVTPG 659
Cdd:COG1629   558 PPLTANLGLTYEFPGGWSLGLGVRYVGDRYLDDANTQGAPGgYTLVDLGAGYR-FGDNLTLSLGVDNLFDKKYATSLSVR 636


                  ....
gi 2687072581 660 YNDA 663
Cdd:COG1629   637 ASNV 640
FhuE COG4773
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ...
 9-686 1.72e-46

Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];


Pssm-ID: 443805 [Multi-domain]  Cd Length: 692  Bit Score: 175.47  E-value: 1.72e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581   9 SCLGLLAAFAATQPALAAP--AVELGQVLITDEEQNDLSAASER----------LREVPGASNLVDMQRVGQGRVASNQD 76
Cdd:COG4773     8 SGLAAAAAGALAQAAAAAAaeATTLPEVTVTGTAEGTGGYTAKSsstatkldtpLRETPQSVSVVTRQLIEDQGATTLDD 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  77 VLAYQPGVFAQSA-GNDGIKLSIRGSGINRapgahgsgvyTMFDGLPLTGPGGTPYELFeplWLSRAEVLRGANGFDQGA 155
Cdd:COG4773    88 ALRNVPGVTVSSYdGGGRDSFSIRGFSIDN----------YLRDGLPLGGFGGGQPDTA---NLERVEVLKGPAGLLYGA 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 156 LALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVL---GNLDYYVALTDSEYDGYQAHSSGSAKGVAANVGYR 232
Cdd:COG4773   155 GSPGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRATADVGGPLnedGTLRYRLNAAYEDGDSFRDGVDNRRTLIAPSLDWD 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 233 FNPNLETRFYLRYRETE-NQLAGRLtkeqikhhPRAANPAYLARDDSRPQPGSTWAGNKTTFY------LDDDARLEAGL 305
Cdd:COG4773   235 LTDDTTLTLGAEYQDDDsTGDRGFL--------PLDGTLLDLPRSTNLGEPWDYYDTETTTLFaelehrFNDDWSLRANA 306

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 306 VYHDYPMDLREgpMRLKVAYTDVSGTLN--YFRRDT----------------LFGHESKTTIGW---RTTKHLPNSGASQ 364
Cdd:COG4773   307 RYSDSDRDGRS--AYAYGAPDAATGTLTryASARDGdsrsdsldanlngkfeTGGLEHTLLVGAdysRYDSDSDSATAGT 384

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 365 FTRNGDVFGERTR-DFTYQGSDTVLH-----VGNDLELVPDLWLTTGLAmiYTRRESDVTFPAEGGKVSMHDWDYAPRLG 438
Cdd:COG4773   385 INIYNPVYGNLPEpDFDASDTDTTTRqtglyAQDQISLTDRLSLLLGGR--YDWYETDSTNRLGGSTTSYDDSAFTPRAG 462

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 439 LRYDISPDLQVYGNLSRSVEPphpwsliwSSPTPNQPIEMQNQTATTLELGTRGESALGHWD--LAWYysQVRHELLAVE 516
Cdd:COG4773   463 LVYDLTPGLSLYASYSESFEP--------QSGADNNGNPLDPETGKQYEAGVKGELFDGRLNatLAVF--DITQKNVATT 532

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 517 IVQGAPAKEfNASATVHQGVEAGLDSTLWERtgtgkLSLRQAYTFSDFHYRDDDTFGD-NRLPGIPMHYYQAELRYDWPN 595
Cdd:COG4773   533 DPDNPNFYV-QVGEVRSRGVELELSGELTPG-----LNLIAGYTYTDAKITKDADALEgKRLTNVPRHTASLWTTYRFPS 606

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 596 GFY------AGVNTQmaSKVQVDYANSYHADEYALLGARLGWDsPKQDWQTWLDLRNLTNKRYAATVTpgyndagkDNAR 669
Cdd:COG4773   607 GALkglglgGGVRYV--GERYGDAANTFTLPSYTLVDAGARYD-LGKNWTLQLNVNNLFDKKYYASSG--------SRGY 675

                         730
                  ....*....|....*..
gi 2687072581 670 STPGEGFAVYAGVSYSF 686
Cdd:COG4773   676 VYYGAPRNVRLSLSYKF 692
ligand_gated_channel cd01347
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ...
 62-686 6.46e-44

TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.


Pssm-ID: 238657 [Multi-domain]  Cd Length: 635  Bit Score: 167.24  E-value: 6.46e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  62 DMQRVGQGRVAsnqDVLAYQPGVFAQSAGNDGIK-LSIRGSGINRapgahgsgVYTMFDGLPLTGPGGT--------PYE 132
Cdd:cd01347     9 DIEKQPATSLA---DLLRRIPGVSVTRGGGGGGStISIRGFGPDR--------TLVLVDGLPLASSNYGrgvdlntiPPE 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 133 LFEplwlsRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGS------RGYQHRHISSGQVLGNLDYYVAL 206
Cdd:cd01347    78 LIE-----RVEVLKGPSSALYGSGAIGGVVNIITKRPTDEFGGSVTAGYGSdnsgssGGGGFDVSGALADDGAFGARLYG 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 207 TDSEYDGYQAHSSGSA------KGVAANVGYRFNPNleTRFYLRYRETENQLAGRLTKEQIKHHPRAANPAYLARDDSRP 280
Cdd:cd01347   153 AYRDGDGTIDGDGQADdsdeerYNVAGKLDWRPDDD--TRLTLDAGYQDQDADGPGGTLPANGTGSSLGGGPSSNTNGDR 230

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 281 QPGSTWAGNKTTFYL------DDDARLEAGLVYHDYPMDLREGPMRLKVAYTDVSGTLNYFRrdtlfghESKTTIGWRTT 354
Cdd:cd01347   231 DWDYRDRYRKRASLGlehdlnDTGWTLRANLSYSYTDNDGDPLILNGGNNAAGGDLGRSGYS-------SERDTTQLGFD 303

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 355 KHLPNSGASQFTRNGDVFGERTRDFTYQGSDTVLHVGNDLELVPDLWLTTGLAMIYTRRESDvTFPAEGGKVSMHDWDYA 434
Cdd:cd01347   304 AGLNAPFGTGPVAHTLTLGVEYRREELDEKQTALYAQDTIELTDDLTLTLGLRYDHYDQDSK-DTIAGGTTAKKSYSHWS 382

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 435 PRLGLRYDISPDLQVYGNLSRSVEPPHPW------SLIWSSPTPNQPIEMqnQTATTLELGTRGESALG-HWDLAWYYSQ 507
Cdd:cd01347   383 PSLGLVYKLTDGLSLYASYSQGFRAPSLGelygggSHGGTAAVGNPNLKP--EKSKQYELGLKYDPGDGlTLSAALFRID 460

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 508 VRHELLAVEIVQGAPAKEF--NASATVHQGVEAGLDSTLWERtgtgkLSLRQAYTFSDFHY-RDDDTFGDNRLPGIPMHY 584
Cdd:cd01347   461 IKNEIVSTPTNTGLGLVTVyvNGGKARIRGVELEASYDLTDG-----LGLTGSYTYTDTEVkRTDGATTGNRLPGIPKHT 535

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 585 YQAELRYDWP-NGFYAGVNTQMASKVQVDYANSYHADE---YALLGARLGWDsPKQDWQTWLDLRNLTNKRYAAtvtpgY 660
Cdd:cd01347   536 ANLGLDYELPdEGLTAGGGVRYRGKQYADTANGNNTVKvpgYTLVDLSASYQ-FTKNLTLRLGVNNLFDKDYYT-----S 609

                         650       660
                  ....*....|....*....|....*.
gi 2687072581 661 NDAGKDNARSTPGEGFAVYAGVSYSF 686
Cdd:cd01347   610 LSVRGSGLYGYYGPGRTYYLSVSYKF 635
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 7-636 1.68e-41

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 160.02  E-value: 1.68e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581   7 LPSCLGLLAAFAATQPALAAPAVELGQVLITDeeqndlSAASERLREVPGASNLV---DMQRVGQGRVAsnqDVLAYQPG 83
Cdd:COG4771     3 LASLLLLLALAAQAADALAEDATELEEVVVTA------TRTEQSLSDAPASVSVItaeEIEKLGATDLA---DALRLLPG 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  84 VFAQSAGNDGI--KLSIRGSGinrapgahGSGVYTMFDGLPLTGP---GGTPYELFEPLWLSRAEVLRGANGFDQGALAL 158
Cdd:COG4771    74 VSVTRSGGRGGssGISIRGLG--------GDRVLVLIDGVPVNNPalgGGGDLSYIPPDDIERIEVIRGPASALYGSDAI 145

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 159 GGAINYVTHTGYDAAPLQVRYEVGS--RGYQHRHISSGQVLGNLDYYVALT--------DSEYDGYQAHSSGSAKGVAAN 228
Cdd:COG4771   146 GGVINIITKKPTDELEGSVSLGYGSngNGTYSGSLSLGGPGDKLSFLLSGSyrdrdgylDYRNGGFVGNSGYERYNLNAK 225

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 229 VGYRFNPNLETRFYLRYRETENQLAGRLTKeqikhhPRAANPAYLARDDSRPQPGSTWAGNKTTFylddDARLEAGLVYH 308
Cdd:COG4771   226 LGYRLSDNHRLSLSGGYSRQDRDGGPPTLG------DTEISSDNAGDRDTTTDRGNYSLRYNGDL----GDNLDLSLYYS 295

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 309 DYPMDLREGPMRLKVAYTDVSGTLNY---FRRDTLFGHESKTTIG--WRTTKHLPNSGASQFTRNGDVFGertrdftyqg 383
Cdd:COG4771   296 RTDRDSTNGSLGGSTGSFSDSDDTTYgleLDLTYPLGGNHTLTLGaeYRYDDLDSSSFLGGADASRDTYG---------- 365

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 384 sdtvLHVGNDLELVPDLWLTTGLamiytRRESDVTFPAEggkvsmHDWDYAPRLGLRYDISPDLQVYGNLSRSVEPPHPW 463
Cdd:COG4771   366 ----LFAQDEWKLTDKLTLTAGL-----RYDYYSTFGAS------NYTAFSPRLGLRYDLSDNLTLRASYGRGFRAPSLA 430

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 464 SLIWSSPTPNQPIEMQN-----QTATTLELGTRGESALGHW--DLAWYYSQVRHELLAVEIVQGAPAKEF--NASATVHQ 534
Cdd:COG4771   431 ELYGSGTGTPGRYVLGNpdlkpETSDNYELGLEYRLGNGGLslSLTGFYTDIKDLIVLVPVGPGPGDVLQyeNVGKARTY 510

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 535 GVEAGLDSTLwertgTGKLSLRQAYTFSDFHYRDDDTfgDNRLPGIPMHYYQAELRYDWPNGFYAGVNTQMASKVQVDY- 613
Cdd:COG4771   511 GLELELKYRL-----GKGLTLTASYTYLDSKIDDGDT--GEPLPNVPPHKANLGLDYRLPKWWLLLLLTRYYGGRYVTPp 583

                         650       660
                  ....*....|....*....|....*
gi 2687072581 614 --ANSYHADEYALLGARLGWDSPKQ 636
Cdd:COG4771   584 sgRLEGYTPGYTLLDLRASYKLTKN 608
Fiu COG4774
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
75-686 1.06e-38

Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];


Pssm-ID: 443806 [Multi-domain]  Cd Length: 639  Bit Score: 151.95  E-value: 1.06e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  75 QDVLAYQPGV-FAQSAGNDGIKLSIRGsginrapgaHGSGVYTMFDGLPLtgPGGTPYELFEplwLSRAEVLRGANGFDQ 153
Cdd:COG4774    30 ADALRNVPGVtFGAGEGGNGDSFSIRG---------FSASGDIYVDGLRD--PGQYRRDTFN---LERVEVLKGPASVLY 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 154 GALALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVLG-NLDYYVALTDSEYDGYQAHSSGSAKGVAANVGYR 232
Cdd:COG4774    96 GRGSPGGVINLVTKRPTDEPFTEVTLTYGSDGQRRATLDVNGPLGdDLAYRLNGMYRDSDSYRDGVDNDRWGIAPSLTWR 175

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 233 FNPNLETRFYLRYRETENQL-AGrltkeqikhHPRAANPAYLARDDSRP--QPGS------TWAGNKTTFYLDDDARLEA 303
Cdd:COG4774   176 LGDRTRLTLDYEYQDDDRTPdYG---------VPAVANGRPVDVDRSTFygQPDDysdsetDSATLRLEHDFNDNWTLRN 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 304 GLVYHDYPMDLREGPMRLKVAYTDVSGTLNYFRRDT----------------------LFG----HESKTTIGWRTTKHL 357
Cdd:COG4774   247 ALRYSDYDRDYRNTYPTGGNATGTVTRSAYRRDQDNdtlsnqtdltgkfdtggvkhtlLAGveysREDSDNARYSGGGTA 326

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 358 PNSGASQFTRNGDVFGE--RTRDFTYQGSDTVLHVGNDLELVPDLWLTTGL------AMIYTRRESDVTFPAEGGKVSmh 429
Cdd:COG4774   327 PTVNLYNPVYGAPVTGPtlGGADNDSRTDTTGLYLQDTISLTDRWSLLAGLrydrfdTDYTDRTTGATTSSYDDSAFS-- 404

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 430 dwdyaPRLGLRYDISPDLQVYGNLSRSVEPPhpwSLIWSSPTPNQPIEMqnQTATTLELGTRGESALGH--WDLAWYYSQ 507
Cdd:COG4774   405 -----PRAGLVYKPTPNLSLYASYSTSFNPG---GGAPSLSNAGQALDP--EKSRQYEVGVKWDLLDGRlsLTAALFRIE 474

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 508 VRHELLAveiVQGAPAKEFNASATVHQGVEAGLDSTLwertgTGKLSLRQAYTFSDFHYRDDDT--FGDNRLPGIPMHYY 585
Cdd:COG4774   475 KTNVRTT---DPANPGVYVQTGEQRSRGVELEATGEL-----TPGWSVLAGYTYLDAEITKSANaaNVGNRLPNVPRHSA 546

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 586 QAELRYDWP-NGFYAGVNTQMASKVQVDYANSYHADEYALLGARLGWDSPKQ-DWQtwLDLRNLTNKRYAATVTPGYnda 663
Cdd:COG4774   547 SLWTTYDLPlPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLNKNlTLR--LNVNNLTDKRYYASAYGSG--- 621

                         650       660
                  ....*....|....*....|...
gi 2687072581 664 gkdnaRSTPGEGFAVYAGVSYSF 686
Cdd:COG4774   622 -----YVTPGAPRTVLLSASYRF 639
TonB_dep_Rec pfam00593
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
 211-685 7.46e-34

TonB dependent receptor; This model now only covers the conserved part of the barrel structure.


Pssm-ID: 395474 [Multi-domain]  Cd Length: 475  Bit Score: 135.67  E-value: 7.46e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 211 YDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRYRETENQLAGRLTKEQIKHHPRAANPAYLARDDSRPQPGSTW---A 287
Cdd:pfam00593   2 WQLSLDLLGDDTLLTLGYDYSRYTDGLDLGLTLDGYGNDGGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWlstL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 288 GNKTTFYLDDDARLEAGLVYHDYPMDLREGPMRLKVAYTDVSGTLNYFRRDTLFGHESKTTIG-WRTTKHLPNSGASQFT 366
Cdd:pfam00593  82 RLGLRYSSLDGDYTSNSSGLSGAGDYLSDDRLYGLYGLDGDLELSLDLSHDLLLGVELRTAGLdYRRLDDDAYDPYDPAN 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 367 RNGDVFGERTRDftyqgsDTVLHVGNDLELVPDLWLTTGLAMIYTRRESDvTFPAEGGKVSMHDWDYAPRLGLRYDISPD 446
Cdd:pfam00593 162 PSSSSYSDTTTD------SYGLYLQDNIKLTDRLTLTLGLRYDHYSTDGD-DGNGGGDNFSRSYSAFSPRLGLVYKPTDN 234

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 447 LQVYGNLSRSVEPPHPWSLIWSSPTPNQPIEMQN------QTATTLELGTRGESALGHWDLAWYYSQVRHELLAVEIVQG 520
Cdd:pfam00593 235 LSLYASYSRGFRAPSLGELYGSGSGGGGGAVAGGnpdlkpETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDPDGPG 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 521 APAKEF---NASATVHQGVEAGLDSTLWERTGTGKlslrqAYTFSDFHYRDDDTFGDNRLPGIPMHYYQAELRYDWPNGF 597
Cdd:pfam00593 315 LGGTVYtytNVGKARIRGVELELSGRLWGLGLSGG-----GYTYTDADDDADADDTGNPLPNVPRHTANLGLTYDFPLGG 389

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 598 Y---AGVN-TQMASKVQVDYANSYHADEYALLGARLGWDsPKQDWQTWLDLRNLTNKRYAatvtpGYNDAGKDNARSTPG 673
Cdd:pfam00593 390 WgarLGARyVGSGERRYGDAANTFKTPGYTLVDLSAGYR-LNKNLTLRLGVNNLFDKYYK-----RYYSSGGGNLGGYPG 463

                         490
                  ....*....|..
gi 2687072581 674 EGFAVYAGVSYS 685
Cdd:pfam00593 464 PGRTFYLGLSYK 475
TonB-siderophor TIGR01783
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ...
 53-686 9.10e-25

TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]


Pssm-ID: 273805 [Multi-domain]  Cd Length: 651  Bit Score: 109.42  E-value: 9.10e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  53 EVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGNDGIK--LSIRGSGINrapgahGSGVYTMFDGLPLTGPGGtp 130
Cdd:TIGR01783   1 DIPQSVSVITRQELEDQQAGSLSEALQRVPGVVVGGSGGTTQFgnITIRGFGLE------VDIDNVYLDGVPLLSRGN-- 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 131 YELFEPLWLSRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVLG---NLDYYVALT 207
Cdd:TIGR01783  73 LAIVDPAMVERVEVLRGPASLLYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGGPLGadgTFRGRLNGA 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 208 DSEYDGYQAHSSGSAKGVAANVGYRFNPNLETRFYLRYR-ETENQLAGRLTKEQIKHHPRAANPAYLARDDSRP------ 280
Cdd:TIGR01783 153 RQDGDSFYDGAGEETRLGATATDWQLDDRTLLRLGAYYQkERDRGGYGGLPASGGTSGRDLSSDRYLGTSSNRNyddrey 232

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 281 ---------QPGSTWAGNKTTFYL---DDDARLEAGLVY---HDYPMDLREGPMRLKVaytdVSGTLNYFRRDTLFGHES 345
Cdd:TIGR01783 233 lsyglsleyQFNDVWTGKQNLRYSyfdTDSNQVQASGYSsdgGLFGRSLTVVNVKQDR----VQIDAGLDGEFETGPIEH 308

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 346 KTTIGWRTTKHLPNSGASQF-----TRNGDVFGERTRDFTYQGSDTVL--------HVGNDLELVPDLWLTTgLAMIYTR 412
Cdd:TIGR01783 309 DLLLGVSYGQRTTNRFNNTGypsdnIYSLTATSSARTDIGDSPKDRALssttkalnGVALQRILLADKWTLT-LGGRYDS 387

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 413 RESDVTFPAEGGKVSMHDWDYAPRLGLRYDISPDLQVYGNLSRSVEPPhpwsLIWSSPTPNQPIEMQNQTATTLELGTRG 492
Cdd:TIGR01783 388 VDVKSNNGVAGSTGKRDDSQFTPSLGVAYKPTDDWSLYASYAESFKPG----GYYPKGAGNSGDILEPEKGKNYELGVRY 463

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 493 ESAlGHW--DLAWYYSQVRHELlaveiVQGAPAKEF--NASATVHQGVEAGLDSTLwertgTGKLSLRQAYTFSDFHYRD 568
Cdd:TIGR01783 464 DLG-DSLlaTAALFRITKDNQL-----VQDPVNGTFsvNAGKTRNRGVELEARGYL-----TPGLSLSAGYTYTDAEFTE 532

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 569 DD--TFGDNRLPGIPMHY------YQAelrYDWPNGFYAGVNTQMASKVQVDYANSYHADEYALLGARLGWDSPKQDWQT 640
Cdd:TIGR01783 533 DTngDTQGNTVPFVPKHTaslwasYAP---PVGDNGLTLGGGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKKKNLT 609

                         650       660       670       680
                  ....*....|....*....|....*....|....*....|....*..
gi 2687072581 641 W-LDLRNLTNKRYaatVTPGYNDAGkdNARSTPGEGFAVYAGVSYSF 686
Cdd:TIGR01783 610 LaLNVNNLFDRDY---YTSGYRWGP--SAYIYPGAPRTVGLSVSYDF 651
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
45-254 9.59e-25

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 104.57  E-value: 9.59e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  45 SAASERLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGNDGI--KLSIRGSGINRapgahgsgVYTMFDGLP 122
Cdd:COG4206     6 TRLEQSKSDLTGSVTVIDAEELERSGATSLADALRRVPGVQVSSSGGPGSaaSISIRGLGSNQ--------TLVLIDGVP 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581 123 LTGP--GGTPYELFEPLWLSRAEVLRGANGFDQGALALGGAINYVTHTGYDAAPLQVRYEVGSRGYQHRHISSGQVLGNL 200
Cdd:COG4206    78 LNDPslGGVDLSLIPPDDIERIEVLKGAASALYGSDAIGGVINITTKKGKKGFKGSVSASYGSFGTRRLSASLSGGAGKF 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2687072581 201 DYYVALTDSEYDGYQAHSSGSA-------KGVAANVGYRFNPNLETRFYLRYRETENQLAG 254
Cdd:COG4206   158 SYSLSASYRRSDGYRYNDPDLRnndgyenTSLNARLGYKLGDNGSLSLSGGYSDSERGYPG 218
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 50-161 1.66e-14

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 69.99  E-value: 1.66e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  50 RLREVPGASNLVDMQRVGQGRVASNQDVLAYQPGVFAQSAGNDGI-KLSIRGSGINRapgahgsgVYTMFDGLPLTGPGG 128
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALRGVPGVSVSSGGGGGGsSISIRGFGSNR--------VLVLVDGVPLNSGGG 72

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2687072581 129 TPYEL--FEPLWLSRAEVLRGANGFDQGALALGGA 161
Cdd:pfam07715  73 GSVDLnsIDPEDIERVEVLKGPASALYGSGAIGGV 107
PRK14050 PRK14050
TonB-dependent siderophore receptor;
45-165 2.68e-05

TonB-dependent siderophore receptor;


Pssm-ID: 237595 [Multi-domain]  Cd Length: 728  Bit Score: 47.49  E-value: 2.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  45 SAASERLREVPGASNLVDMQRVgQGRVASNQ--DVLAYQPGVFAQSAGNDGIK--LSIRGSGinrapgAHGSGVYtmFDG 120
Cdd:PRK14050   70 SKTDTPITEIPQSVSVVGRQEM-DDRGVTNKvdEALRYTPGVLSQPFGTDGDTdwFYIRGFD------ATQTGVF--LDG 140

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2687072581 121 LPL--TGPGGTpyeLFEPLWLSRAEVLRGANGFDQGALALGGAINYV 165
Cdd:PRK14050  141 LNLfsYGFGGF---QIDPFMLERVEVLKGPASVLYGGSNPGGIVNMV 184
btuB PRK10641
TonB-dependent vitamin B12 receptor BtuB;
76-199 5.38e-04

TonB-dependent vitamin B12 receptor BtuB;


Pssm-ID: 236730 [Multi-domain]  Cd Length: 614  Bit Score: 43.06  E-value: 5.38e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  76 DVLAYQPGV-FAQSAG-NDGIKLSIRGSginrapgaHGSGVYTMFDGLPLTGPGGTPYELFEPLWLS---RAEVLRGANG 150
Cdd:PRK10641   64 DVLRRLPGVdIAQNGGlGQLSSLFIRGT--------NSSHVLVLIDGVRLNQAGISGSADLSQIPISlvqRIEYIRGPRS 135

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2687072581 151 FDQGALALGGAINYVTHTGYDAAPLQVryEVGSRGYQHRHISSGQVLGN 199
Cdd:PRK10641  136 AVYGSDAIGGVVNIITTRDKPGTTLSA--GWGSNGYQNYDGSTQQQLGD 182
PRK10003 PRK10003
ferric-rhodotorulic acid outer membrane transporter; Provisional
 7-165 1.90e-03

ferric-rhodotorulic acid outer membrane transporter; Provisional


Pssm-ID: 236640 [Multi-domain]  Cd Length: 729  Bit Score: 41.39  E-value: 1.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581   7 LPSCLGLLAAFAATQPA-LAAPA------VELGQVLITDEEQNDLS----AASERL----REVPGASNLVDMQRVGQGRV 71
Cdd:PRK10003   16 KPSLLAGCIALALLPSAaFAAPAtedtviVEGSATAPVDDGEQDYSvkttSAGTKMqmtqRDIPQSVSIVSQQRMEDQQL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2687072581  72 ASNQDVLAYQPGVFAQSAGNDGIKLSIRGSGINRapgahgsgvyTMFDGLPLT-------GPGGTPYELFEplwlsRAEV 144
Cdd:PRK10003   96 QTLGEVMENTLGISKSQADSDRALYYSRGFQIDN----------YMVDGIPTYfesrwnlGDALSDTALFE-----RVEV 160

                         170       180
                  ....*....|....*....|.
gi 2687072581 145 LRGANGFDQGALALGGAINYV 165
Cdd:PRK10003  161 VRGATGLMTGTGNPSAAINMV 181
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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