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Conserved domains on  [gi|2668360147|ref|WP_330362004|]
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transposase, partial [Lachnospira multipara]

Protein Classification

transposase( domain architecture ID 708174)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0046872|GO:0006313|GO:0003677|GO:0004803|GO:0032196|GO:0015074|GO:0006310
PubMed:  11774877|20215432|20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3666 super family cl26086
Transposase, IS1182 family [Mobilome: prophages, transposons];
16-65 8.63e-10

Transposase, IS1182 family [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG3666:

Pssm-ID: 442883 [Multi-domain]  Cd Length: 169  Bit Score: 51.04  E-value: 8.63e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2668360147  16 GRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYL----MDRETPSY 65
Cdd:COG3666    55 GRPAYDPEMLLKLLLYGYL-EGIRSSRQLEEACRYNLAFRWLlgleLDDPVPDH 107
 
Name Accession Description Interval E-value
COG3666 COG3666
Transposase, IS1182 family [Mobilome: prophages, transposons];
16-65 8.63e-10

Transposase, IS1182 family [Mobilome: prophages, transposons];


Pssm-ID: 442883 [Multi-domain]  Cd Length: 169  Bit Score: 51.04  E-value: 8.63e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2668360147  16 GRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYL----MDRETPSY 65
Cdd:COG3666    55 GRPAYDPEMLLKLLLYGYL-EGIRSSRQLEEACRYNLAFRWLlgleLDDPVPDH 107
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
 1-57 2.66e-06

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 42.31  E-value: 2.66e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2668360147   1 MNLEKYLKNVPEHKLGRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYL 57
Cdd:NF033551   34 LDLSELFADLYCSDNGRPAYHPALMLKLLLYGYL-EGIRSDRQLERELRENLAYRWL 89
DUF772 pfam05598
Transposase domain (DUF772); This presumed domain is found at the N-terminus of many proteins ...
 16-58 1.33e-05

Transposase domain (DUF772); This presumed domain is found at the N-terminus of many proteins found in transposons.


Pssm-ID: 461687 [Multi-domain]  Cd Length: 71  Bit Score: 38.24  E-value: 1.33e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 2668360147 16 GRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYLM 58
Cdd:pfam05598  1 GRPAYPPEMMLKALLLQYL-YGLRSDRQLEEALRDNLSFRWFL 42
 
Name Accession Description Interval E-value
COG3666 COG3666
Transposase, IS1182 family [Mobilome: prophages, transposons];
16-65 8.63e-10

Transposase, IS1182 family [Mobilome: prophages, transposons];


Pssm-ID: 442883 [Multi-domain]  Cd Length: 169  Bit Score: 51.04  E-value: 8.63e-10
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2668360147  16 GRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYL----MDRETPSY 65
Cdd:COG3666    55 GRPAYDPEMLLKLLLYGYL-EGIRSSRQLEEACRYNLAFRWLlgleLDDPVPDH 107
transpos_IS1182 NF033551
IS1182 family transposase; Members of this family are transposases of the IS1182 family. ...
 1-57 2.66e-06

IS1182 family transposase; Members of this family are transposases of the IS1182 family. About two-thirds of the members of this family have an extra domain between the middle and the C-terminal domain, about 50 amino acids in size and containing four invariant Cys residues.


Pssm-ID: 468080 [Multi-domain]  Cd Length: 437  Bit Score: 42.31  E-value: 2.66e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 2668360147   1 MNLEKYLKNVPEHKLGRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYL 57
Cdd:NF033551   34 LDLSELFADLYCSDNGRPAYHPALMLKLLLYGYL-EGIRSDRQLERELRENLAYRWL 89
DUF772 pfam05598
Transposase domain (DUF772); This presumed domain is found at the N-terminus of many proteins ...
 16-58 1.33e-05

Transposase domain (DUF772); This presumed domain is found at the N-terminus of many proteins found in transposons.


Pssm-ID: 461687 [Multi-domain]  Cd Length: 71  Bit Score: 38.24  E-value: 1.33e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 2668360147 16 GRIRYNPVKMLKTVLFGFMsEGYISLRRLQENCKVNIRFMYLM 58
Cdd:pfam05598  1 GRPAYPPEMMLKALLLQYL-YGLRSDRQLEEALRDNLSFRWFL 42
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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