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Conserved domains on  [gi|2648899391|ref|WP_324737645|]
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IS66 family transposase zinc-finger binding domain-containing protein, partial [Pseudomonas sp. A2]

Protein Classification

transposase( domain architecture ID 11465802)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism

Gene Ontology:  GO:0006313|GO:0003677|GO:0004803|GO:0046872|GO:0032196|GO:0015074|GO:0006310
PubMed:  20615441|11774877|20215432|20885819|17165262

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
1-126 3.50e-31

Transposase [Mobilome: prophages, transposons];


:

Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 114.36  E-value: 3.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648899391   1 QLPLFDEAESLAEPLDEADDEEVVAPTKRRGKRKPLPADLPRIEVVHELPEHELTCACgcrkHAIGEEVSEQLEIVPMQI 80
Cdd:COG3436    35 LQLLELEEEAEEEEEAAEEAEAKTTKKKPKPGRKPMPEHLPREEVLHEPTDMRKIDGL----AAIGEEVSEELDLDPGAL 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2648899391  81 RVIKNVRKVYGCRDCESVP-VTADKPAQMIEKSMASPSVLAMLLTTK 126
Cdd:COG3436   111 FVFRNRRDKYKCLYCDGTGlVYAPAPAKRLEKGLAGPGLLAHILVSK 157
 
Name Accession Description Interval E-value
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
1-126 3.50e-31

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 114.36  E-value: 3.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648899391   1 QLPLFDEAESLAEPLDEADDEEVVAPTKRRGKRKPLPADLPRIEVVHELPEHELTCACgcrkHAIGEEVSEQLEIVPMQI 80
Cdd:COG3436    35 LQLLELEEEAEEEEEAAEEAEAKTTKKKPKPGRKPMPEHLPREEVLHEPTDMRKIDGL----AAIGEEVSEELDLDPGAL 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2648899391  81 RVIKNVRKVYGCRDCESVP-VTADKPAQMIEKSMASPSVLAMLLTTK 126
Cdd:COG3436   111 FVFRNRRDKYKCLYCDGTGlVYAPAPAKRLEKGLAGPGLLAHILVSK 157
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
 26-126 1.94e-30

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 111.91  E-value: 1.94e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648899391  26 PTKRRGKRKPLPADLPRIEVVHElPEhelTCA-CGCRK-HAIGEEVSEQLEIVPMQIRVIKNVRKVYGCRDCESVpVTAD 103
Cdd:NF033517    2 PGHKGKTRKPLPDHLPREEVVHE-PE---SCPcCGGALlHRIGEEVSEQLEIIPAKFEVTEYVRPKYACRHCGTV-VQAP 76

                          90       100
                  ....*....|....*....|...
gi 2648899391 104 KPAQMIEKSMASPSVLAMLLTTK 126
Cdd:NF033517   77 APARVIPKGQAGPRLLAHVAVLK 99
zf-IS66 pfam13005
zinc-finger binding domain of transposase IS66; This is a zinc-finger region of the N-terminus ...
 53-96 2.20e-09

zinc-finger binding domain of transposase IS66; This is a zinc-finger region of the N-terminus of the insertion element IS66 transposase.


Pssm-ID: 463770 [Multi-domain]  Cd Length: 46  Bit Score: 49.62  E-value: 2.20e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2648899391  53 ELTCA-CGCRKHAIGEE-VSEQLEIVPMQIRVIKNVRKVYGCRDCE 96
Cdd:pfam13005   1 ERVCPcCGGLLHPIGEDeVREELDIPPAKFRVIEHIRPKYACRHCE 46
 
Name Accession Description Interval E-value
COG3436 COG3436
Transposase [Mobilome: prophages, transposons];
1-126 3.50e-31

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442662 [Multi-domain]  Cd Length: 416  Bit Score: 114.36  E-value: 3.50e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648899391   1 QLPLFDEAESLAEPLDEADDEEVVAPTKRRGKRKPLPADLPRIEVVHELPEHELTCACgcrkHAIGEEVSEQLEIVPMQI 80
Cdd:COG3436    35 LQLLELEEEAEEEEEAAEEAEAKTTKKKPKPGRKPMPEHLPREEVLHEPTDMRKIDGL----AAIGEEVSEELDLDPGAL 110

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2648899391  81 RVIKNVRKVYGCRDCESVP-VTADKPAQMIEKSMASPSVLAMLLTTK 126
Cdd:COG3436   111 FVFRNRRDKYKCLYCDGTGlVYAPAPAKRLEKGLAGPGLLAHILVSK 157
transpos_IS66 NF033517
IS66 family transposase; Members of this protein family are DDE transposases from the IS66 ...
 26-126 1.94e-30

IS66 family transposase; Members of this protein family are DDE transposases from the IS66 family insertion sequences, which typically consist of two accessary genes (TnpA and TnpB) and the third gene encoding the transposase.


Pssm-ID: 468053 [Multi-domain]  Cd Length: 388  Bit Score: 111.91  E-value: 1.94e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2648899391  26 PTKRRGKRKPLPADLPRIEVVHElPEhelTCA-CGCRK-HAIGEEVSEQLEIVPMQIRVIKNVRKVYGCRDCESVpVTAD 103
Cdd:NF033517    2 PGHKGKTRKPLPDHLPREEVVHE-PE---SCPcCGGALlHRIGEEVSEQLEIIPAKFEVTEYVRPKYACRHCGTV-VQAP 76

                          90       100
                  ....*....|....*....|...
gi 2648899391 104 KPAQMIEKSMASPSVLAMLLTTK 126
Cdd:NF033517   77 APARVIPKGQAGPRLLAHVAVLK 99
zf-IS66 pfam13005
zinc-finger binding domain of transposase IS66; This is a zinc-finger region of the N-terminus ...
 53-96 2.20e-09

zinc-finger binding domain of transposase IS66; This is a zinc-finger region of the N-terminus of the insertion element IS66 transposase.


Pssm-ID: 463770 [Multi-domain]  Cd Length: 46  Bit Score: 49.62  E-value: 2.20e-09
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2648899391  53 ELTCA-CGCRKHAIGEE-VSEQLEIVPMQIRVIKNVRKVYGCRDCE 96
Cdd:pfam13005   1 ERVCPcCGGLLHPIGEDeVREELDIPPAKFRVIEHIRPKYACRHCE 46
LZ_Tnp_IS66 pfam13007
Transposase C of IS166 homeodomain; This is a leucine-zipper-like or homeodomain-like region ...
 1-45 1.02e-07

Transposase C of IS166 homeodomain; This is a leucine-zipper-like or homeodomain-like region of transposase TnpC of insertion element IS66.


Pssm-ID: 463771 [Multi-domain]  Cd Length: 67  Bit Score: 45.72  E-value: 1.02e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 2648899391   1 QLPLfdEAESLAEPLDEADDEEVVAPTKRRGKRKPLPADLPRIEV 45
Cdd:pfam13007  25 QLEL--ALEELEAEEAEVEAEARASKKRKKPGRKPLPAHLPREEV 67
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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