|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-632 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 754.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 6 APDGILTKAIRGFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRS----GAKVIISTGSKALQDQLYA 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 82 RDLPTVRDALKFTGKLALLKGRSNYLCLERLEQqSMVGGELASDALSDLMHLRGWSIQTEDGDVSNCHGvSEDSTIWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELPL-PEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 162 TSTNDNCLGSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQQ 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 242 LTSRQLMDLAKDITIAYRTevRDTAQLQKCADRLSQSAQDFRLALGD-PGYRGNLREAL-ALPEVQRALVLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPdEPEELLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 320 DVVKMSLGRSALLDAAFERATLYRNRLKR-LRDVSIPGYSYWYECNSRHFVMALTPLTVAEKFSEVMKEKPGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 399 LAVNDDVSHFTARLGL-NKAKSLLLPSPFDYANQAMLCVPRFLPTPNQR-GAARQLARMLRPVIEANEGRCFFLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLdEDARTLSLPSPFDYENQALLYVPRDLPRPSDRdGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 477 MRDLAEEFRATMTLPVLLQGETSKPRLLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2551293611 557 CRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAPRTRdLNKVITFLKA 632
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLER 627
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
11-618 |
6.10e-134 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 415.50 E-value: 6.10e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 11 LTKAIRGFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVP----ALRSGAKVIISTGSKALQDQLYARDLPT 86
Cdd:PRK08074 249 LSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKDIPL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 87 VRDALKFTGKLALLKGRSNYLCLERLEQqsmvggELASD------ALSDLMHLRgWSIQTEDGDVSNCHGVSEDSTIWPL 160
Cdd:PRK08074 329 LQKIFPFPVEAALLKGRSHYLCLRKFEQ------ALQEEddnydvALTKAQLLV-WLTETETGDLDELNLPSGGKLLWNR 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 161 VTSTNDNCLGSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQ 240
Cdd:PRK08074 402 IASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEE----PLLPSYEHIIIDEAHHFEEAASRHLGE 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 241 QLTSRQL-------------MDLAKDITIAYRTEVRDTAQLQKC----------ADRLSQSAQDF------RLALGDPGY 291
Cdd:PRK08074 478 QFSYMSFqlllsrlgtleedGLLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNGRLIY 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 292 R-----GNLREALALPEVQRALVL----LDDALELCYDVV--KMSLGRSALLDAAFERATL--YRNRLKRLRDVSIPGYS 358
Cdd:PRK08074 558 RyntesEKGKLWDAITELANRLCYdlrdLLTLLEAQKKELqeKMESESAFLTGEYAHLIDLleKMAQLLQLLFEEDPDYV 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 359 YWYECNSRHFVMALT----PLTVAEKFSE--VMKEKpgSWIFTSATLAVNDDVSHFTARLGLNK--AKSLLLPSPFDYAN 430
Cdd:PRK08074 638 TWIEIDAKGAINATRlyaqPVEVAERLADefFAKKK--SVILTSATLTVNGSFDYIIERLGLEDfyPRTLQIPSPFSYEE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 431 QAMLCVPRFLPT---PNQRGAARQLARMLRPVIEANEGRCFFLCTSHAMMRDLAEEFRATMTLP--VLL-QGET--SKPR 502
Cdd:PRK08074 716 QAKLMIPTDMPPikdVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSsgSRAR 795
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 503 LLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCRIRGGDPFAEVQLPDAVITLKQGVG 582
Cdd:PRK08074 796 LTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQGFG 875
|
650 660 670
....*....|....*....|....*....|....*.
gi 2551293611 583 RLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAP 618
Cdd:PRK08074 876 RLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-624 |
1.07e-87 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 291.32 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 17 GFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRS---GAKVIISTGSKALQDQLYARDLPTVRDALKF 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALYYaitEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 94 TGKLALLKGRSNYLCLERLEQqSMVGGELASDALSDLMHLRGWSIQTEDGDVSNCHGVSEDSTIWPLVTStnDNCLGSDC 173
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDNTDNYEFNIFKMQVLVWLTETETGDLDELNLKGGNKMFFAQVRH--DGNLSKKD 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 174 PQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQQLTSRQLMDLAKD 253
Cdd:TIGR01407 400 LFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKYQIDL 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 254 ITiayrteVRDTAQLQKcadRLSQSAQDFRLALgdpgyRGNLREALALPEVQRALVLLD----DALELCYDVVKmslgrs 329
Cdd:TIGR01407 476 IG------KGENEQLLK---RIQQLEKQEILEK-----LFDFETKDILKDLQAILDKLNkllqIFSELSHKTVD------ 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 330 alldaAFERATLY-RNRLKRLRDVSIPGYSYWYEC----NSRHFVMALTPLTVAEKFSEVMKEKPGSWIFTSATLAVNDD 404
Cdd:TIGR01407 536 -----QLRKFDLAlKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHS 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 405 VSHFTARLGLNKAK-SLLLPSPFDYANQAMLCVPRFLPT---PNQRGAARQLARMLRPVIEANEGRCFFLCTSHAMMR-- 478
Cdd:TIGR01407 611 FESFPQLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPAiqnKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLHmv 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 479 -DLAEEFRATMTLPVLLQGETSKP-RLLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIED 556
Cdd:TIGR01407 691 yDMLNELPEFEGYEVLAQGINGSRaKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQK 770
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2551293611 557 CRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAPRTRDLN 624
Cdd:TIGR01407 771 LEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYLQVKGDI 838
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-616 |
7.77e-50 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 170.82 E-value: 7.77e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 459 VIEANEGRCFFLCTSHAMMRDLAEEFRATMT---LPVLLQ-GETSKPRLLAEFVAAG-NALLVATS--SFWEGVDVRGDT 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 532 LSCVIIDKLPFTSPDDPLLKARIEDCRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*
gi 2551293611 612 NSLPP 616
Cdd:pfam13307 163 KWLPP 167
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
2.44e-39 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 141.26 E-value: 2.44e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 474 HAMMRDLAEEFRATMTL----PVLLQGETSKPR--LLAEFVAAGN---ALLVATSS--FWEGVDVRGDTLSCVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGETeeLLEKYSAACEargALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2551293611 543 TSPDDPLLKARIEDCRIRG-GDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
523-600 |
4.01e-10 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 58.77 E-value: 4.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 523 EGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCR-------IRGGDPFAEvqlpDAVITLKQGVGRLIRDTSDRGVVI 595
Cdd:cd18788 78 EGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAMRAVNQAIGRAIRHKNDYGAIV 153
|
....*
gi 2551293611 596 ICDNR 600
Cdd:cd18788 154 LLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
6-632 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 754.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 6 APDGILTKAIRGFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRS----GAKVIISTGSKALQDQLYA 81
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARALAEGRHLLIEAGTGTGKTLAYLVPALLAaretGKKVVISTATKALQEQLVE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 82 RDLPTVRDALKFTGKLALLKGRSNYLCLERLEQqSMVGGELASDALSDLMHLRGWSIQTEDGDVSNCHGvSEDSTIWPLV 161
Cdd:COG1199 81 KDLPLLRKALGLPLRVALLKGRSNYLCLRRLEQ-ALQEGDDLDDEELLLARILAWASETWTGDRDELPL-PEDDELWRQV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 162 TSTNDNCLGSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQQ 241
Cdd:COG1199 159 TSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALGE----ELLPEDDVLIIDEAHNLPDRARDMFSAE 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 242 LTSRQLMDLAKDITIAYRTevRDTAQLQKCADRLSQSAQDFRLALGD-PGYRGNLREAL-ALPEVQRALVLLDDALELCY 319
Cdd:COG1199 235 LSSRSLLRLLRELRKLGLR--PGLKKLLDLLERLREALDDLFLALEEeEELRLALGELPdEPEELLEALDALRDALEALA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 320 DVVKMSLGRSALLDAAFERATLYRNRLKR-LRDVSIPGYSYWYECNSRHFVMALTPLTVAEKFSEVMKEKPGSWIFTSAT 398
Cdd:COG1199 313 EALEEELERLAELDALLERLEELLFALARfLRIAEDEGYVRWLEREGGDVRLHAAPLDPADLLRELLFSRARSVVLTSAT 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 399 LAVNDDVSHFTARLGL-NKAKSLLLPSPFDYANQAMLCVPRFLPTPNQR-GAARQLARMLRPVIEANEGRCFFLCTSHAM 476
Cdd:COG1199 393 LSVGGPFDYFARRLGLdEDARTLSLPSPFDYENQALLYVPRDLPRPSDRdGYLEAIAEAIAELLEASGGNTLVLFTSYRA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 477 MRDLAEEFRATMTLPVLLQGETSKPRLLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIED 556
Cdd:COG1199 473 LEQVAELLRERLDIPVLVQGDGSREALLERFREGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREA 552
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2551293611 557 CRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAPRTRdLNKVITFLKA 632
Cdd:COG1199 553 LEARGGNGFMYAYLPPAVIKLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTR-PEELRAFLER 627
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
11-618 |
6.10e-134 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 415.50 E-value: 6.10e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 11 LTKAIRGFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVP----ALRSGAKVIISTGSKALQDQLYARDLPT 86
Cdd:PRK08074 249 LSLAMPKYEKREGQQEMMKEVYTALRDSEHALIEAGTGTGKSLAYLLPaayfAKKKEEPVVISTYTIQLQQQLLEKDIPL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 87 VRDALKFTGKLALLKGRSNYLCLERLEQqsmvggELASD------ALSDLMHLRgWSIQTEDGDVSNCHGVSEDSTIWPL 160
Cdd:PRK08074 329 LQKIFPFPVEAALLKGRSHYLCLRKFEQ------ALQEEddnydvALTKAQLLV-WLTETETGDLDELNLPSGGKLLWNR 401
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 161 VTSTNDNCLGSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQ 240
Cdd:PRK08074 402 IASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEE----PLLPSYEHIIIDEAHHFEEAASRHLGE 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 241 QLTSRQL-------------MDLAKDITIAYRTEVRDTAQLQKC----------ADRLSQSAQDF------RLALGDPGY 291
Cdd:PRK08074 478 QFSYMSFqlllsrlgtleedGLLSKLAKLFKKSDQASRSSFRDLdeslkelkfeADELFQMLRSFvlkrkkQEQNGRLIY 557
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 292 R-----GNLREALALPEVQRALVL----LDDALELCYDVV--KMSLGRSALLDAAFERATL--YRNRLKRLRDVSIPGYS 358
Cdd:PRK08074 558 RyntesEKGKLWDAITELANRLCYdlrdLLTLLEAQKKELqeKMESESAFLTGEYAHLIDLleKMAQLLQLLFEEDPDYV 637
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 359 YWYECNSRHFVMALT----PLTVAEKFSE--VMKEKpgSWIFTSATLAVNDDVSHFTARLGLNK--AKSLLLPSPFDYAN 430
Cdd:PRK08074 638 TWIEIDAKGAINATRlyaqPVEVAERLADefFAKKK--SVILTSATLTVNGSFDYIIERLGLEDfyPRTLQIPSPFSYEE 715
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 431 QAMLCVPRFLPT---PNQRGAARQLARMLRPVIEANEGRCFFLCTSHAMMRDLAEEFRATMTLP--VLL-QGET--SKPR 502
Cdd:PRK08074 716 QAKLMIPTDMPPikdVPIEEYIEEVAAYIAKIAKATKGRMLVLFTSYEMLKKTYYNLKNEEELEgyVLLaQGVSsgSRAR 795
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 503 LLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCRIRGGDPFAEVQLPDAVITLKQGVG 582
Cdd:PRK08074 796 LTKQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPPDQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQGFG 875
|
650 660 670
....*....|....*....|....*....|....*.
gi 2551293611 583 RLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAP 618
Cdd:PRK08074 876 RLIRTETDRGTVFVLDRRLTTTSYGKYFLESLPTVP 911
|
|
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
11-622 |
8.90e-114 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 356.06 E-value: 8.90e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 11 LTKAIRGFKPREAQQHMAEAVTKA---IQFKEE--LVVEAGTGTGKTYAYLVP----ALRSGAKVIISTGSKALQDQLYA 81
Cdd:PRK11747 17 LQEQLPGFIPRAGQRQMIAEVAKTlagEYLKDGriLVIEAGTGVGKTLSYLLAgipiARAEKKKLVISTATVALQEQLVS 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 82 RDLPTVRDALKFTGKLALLKGRSNYLCLERLEQqsMVGGELASDALSDLM----------------------HLRGWsiq 139
Cdd:PRK11747 97 KDLPLLLKISGLDFKFTLAKGRGRYVCPRKLAA--LASDEGTQQDLLLFLddeltppdeeeqkllarlakalATGKW--- 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 140 teDGDVSNCHGVSEDStIWPLVTSTNDNCLGSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADLvvkETGFGELIPDA 219
Cdd:PRK11747 172 --DGDRDHWPEPIDDS-LWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADL---ELGGGVVLPDP 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 220 DVMI--FDEAHQLPDIASQYFGQQL----TSRQLMDLAKDIT--IAYRTEVRDTA--QLQKCADRLSQSAQDFRLAL--- 286
Cdd:PRK11747 246 ENLLyvLDEGHHLPDVARDHFAASAelkgTADWLEKLLKLLTklVALIMEPPLALpeRLNAHCEELRELLASLNQILnlf 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 287 -----GDPGYR---GNLREALALP------EVQRALVLLDDALELCYDVVKMSLGRSALLDAAFERATLYRNRLKRLRDV 352
Cdd:PRK11747 326 lpaggEEARYRfemGELPEELLELaerlakLTEKLLGLLEKLLNDLSEAMKTGKIDIVRLERLLLELGRALGRLEALSKL 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 353 -----------SIPgYSYW----YECNSRHFVMALTPLTVAEkfsevMKEK------PGSwIFTSATLAVNDDVSHFTAR 411
Cdd:PRK11747 406 wrlaakedqesGAP-MARWitreERDGQGDYLFHASPIRVGD-----QLERllwsraPGA-VLTSATLRSLNSFDRFQEQ 478
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 412 LGLNK---AKSLLLPSPFDYANQAMLCVPRFLPTPNQRGA-ARQLARMLRPVIEANEGrCFFLCTSHAMMRDLAEEFRAT 487
Cdd:PRK11747 479 SGLPEkdgDRFLALPSPFDYPNQGKLVIPKMRAEPDNEEAhTAEMAEFLPELLEKHKG-SLVLFASRRQMQKVADLLPRD 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 488 MTLPVLLQGETSKPRLLAEF---VAAGNA-LLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCRIRGGD 563
Cdd:PRK11747 558 LRLMLLVQGDQPRQRLLEKHkkrVDEGEGsVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAEWLKSRGGN 637
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*....
gi 2551293611 564 PFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAPRTRD 622
Cdd:PRK11747 638 PFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIE 696
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
17-624 |
1.07e-87 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 291.32 E-value: 1.07e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 17 GFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRS---GAKVIISTGSKALQDQLYARDLPTVRDALKF 93
Cdd:TIGR01407 243 GLEYRPEQLKLAELVLDQLTHSEKSLIEAPTGTGKTLGYLLPALYYaitEKPVVISTNTKVLQSQLLEKDIPLLNEILNF 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 94 TGKLALLKGRSNYLCLERLEQqSMVGGELASDALSDLMHLRGWSIQTEDGDVSNCHGVSEDSTIWPLVTStnDNCLGSDC 173
Cdd:TIGR01407 323 KINAALIKGKSNYLSLGKFSQ-ILKDNTDNYEFNIFKMQVLVWLTETETGDLDELNLKGGNKMFFAQVRH--DGNLSKKD 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 174 PQYKDCFVVKARRRAMDADIIVVNHHLFLADLVVKEtgfgELIPDADVMIFDEAHQLPDIASQYFGQQLTSRQLMDLAKD 253
Cdd:TIGR01407 400 LFYEVDFYNRAQKNAEQAQILITNHAYLITRLVDNP----ELFPSFRDLIIDEAHHLPDIAENQLQEELDYADIKYQIDL 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 254 ITiayrteVRDTAQLQKcadRLSQSAQDFRLALgdpgyRGNLREALALPEVQRALVLLD----DALELCYDVVKmslgrs 329
Cdd:TIGR01407 476 IG------KGENEQLLK---RIQQLEKQEILEK-----LFDFETKDILKDLQAILDKLNkllqIFSELSHKTVD------ 535
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 330 alldaAFERATLY-RNRLKRLRDVSIPGYSYWYEC----NSRHFVMALTPLTVAEKFSEVMKEKPGSWIFTSATLAVNDD 404
Cdd:TIGR01407 536 -----QLRKFDLAlKDDFKNIEQSLKEGHTSWISIenlqQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHS 610
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 405 VSHFTARLGLNKAK-SLLLPSPFDYANQAMLCVPRFLPT---PNQRGAARQLARMLRPVIEANEGRCFFLCTSHAMMR-- 478
Cdd:TIGR01407 611 FESFPQLLGLTDVHfNTIEPTPLNYAENQRVLIPTDAPAiqnKSLEEYAQEIASYIIEITAITSPKILVLFTSYEMLHmv 690
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 479 -DLAEEFRATMTLPVLLQGETSKP-RLLAEFVAAGNALLVATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIED 556
Cdd:TIGR01407 691 yDMLNELPEFEGYEVLAQGINGSRaKIKKRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQK 770
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2551293611 557 CRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSLPPAPRTRDLN 624
Cdd:TIGR01407 771 LEQEGKNPFYDYVLPMAIIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLPEYLQVKGDI 838
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
459-616 |
7.77e-50 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 170.82 E-value: 7.77e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 459 VIEANEGRCFFLCTSHAMMRDLAEEFRATMT---LPVLLQ-GETSKPRLLAEFVAAG-NALLVATS--SFWEGVDVRGDT 531
Cdd:pfam13307 3 LLKVIPGGVLVFFPSYSYLEKVAERLKESGLekgIEIFVQpGEGSREKLLEEFKKKGkGAVLFGVCggSFSEGIDFPGDL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 532 LSCVIIDKLPFTSPDDPLLKARIEDCRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFL 611
Cdd:pfam13307 83 LRAVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLP 162
|
....*
gi 2551293611 612 NSLPP 616
Cdd:pfam13307 163 KWLPP 167
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
474-603 |
2.44e-39 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 141.26 E-value: 2.44e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 474 HAMMRDLAEEFRATMTL----PVLLQGETSKPR--LLAEFVAAGN---ALLVATSS--FWEGVDVRGDTLSCVIIDKLPF 542
Cdd:smart00491 1 YRYLEQVVEYWKENGILeinkPVFIEGKDSGETeeLLEKYSAACEargALLLAVARgkVSEGIDFPDDLGRAVIIVGIPF 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2551293611 543 TSPDDPLLKARIEDCRIRG-GDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVM 603
Cdd:smart00491 81 PNPDSPILRARLEYLDEKGgIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
14-614 |
1.00e-26 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 115.94 E-value: 1.00e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 14 AIRGFKPREAQQHMAEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRSG--AKVIISTGSKALQDQLYARDLPTVRDAl 91
Cdd:PRK07246 240 ALLGLEERPKQESFAKLVGEDFHDGPASFIEAQTGIGKTYGYLLPLLAQSdqRQIIVSVPTKILQDQIMAEEVKAIQEV- 318
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 92 kFTGKLALLKGRSNYLCLERLEQQSMVGGElasDALSDL--MHLRGWSIQTEDGDVSNCHGVSEDSTIWPLVTstNDNCL 169
Cdd:PRK07246 319 -FHIDCHSLKGPQNYLKLDAFYDSLQQNDD---NRLVNRykMQLLVWLTETETGDLDEIKQKQRYAAYFDQLK--HDGNL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 170 GSDCPQYKDCFVVKARRRAMDADIIVVNHHLFLADlVVKETGFGElipdADVMIFDEAHQLPDIASQYFGQQLTSRQLMD 249
Cdd:PRK07246 393 SQSSLFYDYDFWKRSYEKAKTARLLITNHAYFLTR-VQDDKDFAR----NKVLVFDEAQKLMLQLEQLSRHQLNITSFLQ 467
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 250 LAKDITIAYRTEVRDTAqLQKCADRLSQSAQDFrlalgdpgYRGNLREalalpevqralVLLDDALELCYDVVKMSLGRS 329
Cdd:PRK07246 468 TIQKALSGPLPLLQKRL-LESISFELLQLSEQF--------YQGKERQ-----------LIHDSLSRLHQYFSELEVAGF 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 330 ALLDAAFerATLYRNrlkrlrdvsipgysYWYEC--NSRHFVmalTPLTVAEK----FSEVMKEKPGSwIFTSATLAVND 403
Cdd:PRK07246 528 QELQAFF--ATAEGD--------------YWLESekQSEKRV---TYLNSASKafthFSQLLPETCKT-YFVSATLQISP 587
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 404 DVShFTARLGLNKAKSLLLPSpfDYANQAMLCVPRFLPTPNQRG--------AAR--QLARMLRPVieanegrcFFLCTS 473
Cdd:PRK07246 588 RVS-LADLLGFEEYLFHKIEK--DKKQDQLVVVDQDMPLVTETSdevyaeeiAKRleELKQLQQPI--------LVLFNS 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 474 HAMM---RDLAEEfratMTLPVLLQGETSKP-RLLAEFVAAGNALLVATSSFWEGVD-VRGDTLSCVIIdKLPFTSPDDP 548
Cdd:PRK07246 657 KKHLlavSDLLDQ----WQVSHLAQEKNGTAyNIKKRFDRGEQQILLGLGSFWEGVDfVQADRMIEVIT-RLPFDNPEDP 731
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2551293611 549 LLKARIEDCRIRGGDPFAEVQLPDAVITLKQGVGRLIRDTSDRGVVIICDNRLVMRPYGEVFLNSL 614
Cdd:PRK07246 732 FVKKMNQYLLQEGKNPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDRRILTKSYGKQILASL 797
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
523-600 |
4.01e-10 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 58.77 E-value: 4.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 523 EGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCR-------IRGGDPFAEvqlpDAVITLKQGVGRLIRDTSDRGVVI 595
Cdd:cd18788 78 EGIDFSDDLGRAVIMVGIPYPNTKDPILKLKMDDLEylrdkglLTGEDWYTF----QAMRAVNQAIGRAIRHKNDYGAIV 153
|
....*
gi 2551293611 596 ICDNR 600
Cdd:cd18788 154 LLDKR 158
|
|
| Csf4_U |
cd09708 |
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly ... |
34-586 |
4.16e-08 |
|
CRISPR/Cas system-associated DinG family helicase Csf4; CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; DinG family DNA helicase
Pssm-ID: 187839 [Multi-domain] Cd Length: 632 Bit Score: 56.52 E-value: 4.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 34 AIQFKEELVVEAGTGTGKTYAYLVPAL-----RSGAKVIISTGSKALQDQLYA--RDLPTvrDALKFTGKLALLKGRSNY 106
Cdd:cd09708 12 SLRQKRIGMLEASTGVGKTLAMIMAALtmlkeRPDQKIAIAVPTLALMGQLWSelERLTA--EGLAGPVQAGFFPGSQEF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 107 LCLERL----------------EQQSMVGGELASDA------------LSDLMHLRGWSIQTEDGDVSNCHGVSEDSTIW 158
Cdd:cd09708 90 VSPGALqelldqsdgpgdkdavVRLWMGQGGPRKVAplfnrmrdvtllIHDTADIRGYVSYREQWDSLPRCSAMSRAPTK 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 159 ---------PLVT-STNDNCLGSDCPQYKDCFVVKARR-RAMDADIIVVNHhlfladlvvKETGFGeLIPDADVMIFDEA 227
Cdd:cd09708 170 masmthdlkALATlNPQDFVTEDEEDKRWVTSLVESREyYARKSRILACTH---------TMLKWG-LLPQPDILIVDEA 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 228 HQLPDIASQYFGQQLTSRqlmDLAKDITIAYRTEVRDTAQLQKCADRLSQSAQDFRLALGDpgyrgnlrEALALPEVQRA 307
Cdd:cd09708 240 HLFEQNISRVYSNALSLR---MLRFHLEVSHRKTGAIGSAVVAAVSAVSHRLRQVSALGDG--------QTLCLDAGNKE 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 308 LV----LLDDALELCYDVVKMSLgrSALLDAAFERATLyRNRLKRLRDVSIPGYSYWYEcNSRHFVMALTPLTVAEKFSE 383
Cdd:cd09708 309 LEtlfaDLDAALEIKSTPNKKAL--SVVKDVKKARIIL-DNAITAIQGKQSTVYLQFSP-DRRFPSLIVGREDLGKVMGG 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 384 VMKEKPGSWIFTSATL---AVNDDVSHFTARLGLNKAKSLLL-PSPFdYA----NQAMLCV-----PRFLPTPNQRG--- 447
Cdd:cd09708 385 LWKDVTHGAIIVSATLylpDRFGQMSCDYLKRVLSLPLSRLDtPSPI-VApwvrNLIPHLHvpnakARFLLSRPVGKteq 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 448 --AARQ-----LARMLRPVIEANEGRCFFLCTSHAMMRDLAEEFRATMTLPVLLQgeTSKPRL-------LAEFVAAGNA 513
Cdd:cd09708 464 gdANLAgwlenVSLSTAAILRKAQGGTLVLTTAFSHISAIGQLVELGIPAEIVIQ--SEKNRLasaeqqfLALYANGIQP 541
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 514 LLVATSSFWEGVDV--------RGDTLSCVIIDKLPFTspddpLLKARIEDCRIRGGDPFAEVqLPDAVITLKQGVGRLI 585
Cdd:cd09708 542 VLIAAGGAWTGIDLhdpsvspdKDNLLTDLIITCAPFG-----LNRSLSMLKRIRKTSVRPEI-INESLMMLRQGLGRLV 615
|
.
gi 2551293611 586 R 586
Cdd:cd09708 616 R 616
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
12-82 |
8.56e-06 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 47.10 E-value: 8.56e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2551293611 12 TKAIRGFKPREAQQhmaEAVTKAIQFKEELVVEAGTGTGKTYAYLVPALRSGA-----KVIISTGSKALQDQLYAR 82
Cdd:smart00487 1 IEKFGFEPLRPYQK---EAIEALLSGLRDVILAAPTGSGKTLAALLPALEALKrgkggRVLVLVPTRELAEQWAEE 73
|
|
| DEXHc_Hrq1-like |
cd17923 |
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a ... |
25-79 |
1.72e-05 |
|
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350681 [Multi-domain] Cd Length: 182 Bit Score: 45.65 E-value: 1.72e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2551293611 25 QHMAEAVTkAIQFKEELVVEAGTGTGKTYAYLVPAL-----RSGAKVIISTGSKAL-QDQL 79
Cdd:cd17923 3 SHQAEAIE-AARAGRSVVVTTGTASGKSLCYQLPILeallrDPGSRALYLYPTKALaQDQL 62
|
|
| YprA |
COG1205 |
ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain [Replication, ... |
26-79 |
2.93e-04 |
|
ATP-dependent helicase YprA, contains C-terminal metal-binding DUF1998 domain [Replication, recombination and repair];
Pssm-ID: 440818 [Multi-domain] Cd Length: 758 Bit Score: 44.06 E-value: 2.93e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 26 HMAEAVtKAIQFKEELVVEAGTGTGKTYAYLVPALRS-----GAKVIISTGSKAL-QDQL 79
Cdd:COG1205 60 HQAEAI-EAARAGKNVVIATPTASGKSLAYLLPVLEAlledpGATALYLYPTKALaRDQL 118
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
511-600 |
4.39e-04 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 43.55 E-value: 4.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 511 GNALL-VATSSFWEGVDVRGDTLSCVIIDKLPFTSPDDPLLKARIEDCR----IRGGDPFAEVqlpDAVITLKQGVGRLI 585
Cdd:TIGR00604 583 GAVLLsVAGGKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLEFLRdqypIRENQDFYEF---DAMRAVNQAIGRVI 659
|
90
....*....|....*
gi 2551293611 586 RDTSDRGVVIICDNR 600
Cdd:TIGR00604 660 RHKDDYGSIVLLDKR 674
|
|
| DEADc_DDX18 |
cd17942 |
DEAD-box helicase domain of DEAD box protein 18; This DDX18 gene encodes a DEAD box protein ... |
13-84 |
5.53e-04 |
|
DEAD-box helicase domain of DEAD box protein 18; This DDX18 gene encodes a DEAD box protein and is activated by Myc protein. DDX18 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350700 [Multi-domain] Cd Length: 198 Bit Score: 41.58 E-value: 5.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 13 KAIR--GFkpreaqQHMAEAVTKAIQFK---EELVVEAGTGTGKTYAYLVPAL----------RSGAKVIISTGSKALQD 77
Cdd:cd17942 3 KAIEemGF------TKMTEIQAKSIPPLlegRDVLGAAKTGSGKTLAFLIPAIellyklkfkpRNGTGVIIISPTRELAL 76
|
....*....
gi 2551293611 78 QLY--ARDL 84
Cdd:cd17942 77 QIYgvAKEL 85
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
41-82 |
9.38e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 40.30 E-value: 9.38e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 2551293611 41 LVVEAGTGTGKTYAYLVPALRS------GAKVIISTGSKALQDQLYAR 82
Cdd:pfam00270 17 VLVQAPTGSGKTLAFLLPALEAldkldnGPQALVLAPTRELAEQIYEE 64
|
|
| DEXHc_cas3 |
cd17930 |
DEXH/Q-box helicase domain of Cas3; CRISPR-associated (Cas) 3 is a nuclease-helicase ... |
41-137 |
1.63e-03 |
|
DEXH/Q-box helicase domain of Cas3; CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350688 [Multi-domain] Cd Length: 186 Bit Score: 39.97 E-value: 1.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2551293611 41 LVVEAGTGTGKTYAYLVPALRSGA-----KVIISTGSKALQDQLYARdlptVRDALKFTG---KLALLKGRSNylcLERL 112
Cdd:cd17930 4 VILEAPTGSGKTEAALLWALKLAArggkrRIIYALPTRATINQMYER----IREILGRLDdedKVLLLHSKAA---LELL 76
|
90 100
....*....|....*....|....*
gi 2551293611 113 EQQSMVGGELASDALSDLMHLRGWS 137
Cdd:cd17930 77 ESDEEPDDDPVEAVDWALLLKRSWL 101
|
|
| DEXDc_ComFA |
cd17925 |
DEXD-box helicase domain of ComFA; ATP-dependent helicase ComFA (also called ComF operon ... |
23-70 |
2.04e-03 |
|
DEXD-box helicase domain of ComFA; ATP-dependent helicase ComFA (also called ComF operon protein 1) is part of the complex mediating the binding and uptake of single-stranded DNA. ComFA is required for DNA uptake but not for binding. It belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350683 [Multi-domain] Cd Length: 143 Bit Score: 38.82 E-value: 2.04e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 2551293611 23 AQQHMAEAVTKAIQFKEELVVEAGTGTGKT---YAYLVPALRSGAKVIIST 70
Cdd:cd17925 1 GQQKASNALVETIDAKEDLLVWAVTGAGKTemlFPAIAQALRQGGRVAIAS 51
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
173-247 |
2.76e-03 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 40.05 E-value: 2.76e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2551293611 173 CPQYkdcfvvkARRRAMD-ADIIVVNHHLFLADLVVKEtgFGELIPDAdVMIFDEAHQLPDIASQYFGQQLTSRQL 247
Cdd:smart00488 200 CPYF-------ASRKAIEfANVVVLPYQYLLDPKIRQA--LSIELKDS-IVIFDEAHNLDNVCISALSSELSRRSL 265
|
|
| DEAD_2 |
pfam06733 |
DEAD_2; This represents a conserved region within a number of RAD3-like DNA-binding helicases ... |
173-247 |
4.48e-03 |
|
DEAD_2; This represents a conserved region within a number of RAD3-like DNA-binding helicases that are seemingly ubiquitous - members include proteins of eukaryotic, bacterial and archaeal origin. RAD3 is involved in nucleotide excision repair, and forms part of the transcription factor TFIIH in yeast.
Pssm-ID: 399602 [Multi-domain] Cd Length: 168 Bit Score: 38.40 E-value: 4.48e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2551293611 173 CPQYKdcfvvkARRRAMDADIIVVNHHLFLADLVVKETGFgeLIPDAdVMIFDEAHQLPDIASQYFGQQLTSRQL 247
Cdd:pfam06733 103 CPYYL------SRELIPDADIIILPYNYLLDPKIRESLSI--NLKNS-IVIFDEAHNIEDVCIESASFSISRSQL 168
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
18-82 |
8.64e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 39.24 E-value: 8.64e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2551293611 18 FKPREAQQhmaEAVTKAIQFKEE----LVVEAGTGTGKTY--AYLVPALRSGAKVIISTGSKALQDQLYAR 82
Cdd:COG1061 79 FELRPYQQ---EALEALLAALERgggrGLVVAPTGTGKTVlaLALAAELLRGKRVLVLVPRRELLEQWAEE 146
|
|
| |
