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Conserved domains on  [gi|2537297269|ref|WP_293918901|]
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NADH-quinone oxidoreductase subunit I [Apibacter sp.]

Protein Classification

NuoI/complex I 23 kDa subunit family protein( domain architecture ID 11481829)

NuoI/complex I 23 kDa subunit family protein such as bacterial NADH-quinone oxidoreductase subunit I (NuoI), which is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

EC:  7.1.1.-
Gene Ontology:  GO:0016651|GO:0051539|GO:0016020
PubMed:  23417064|33957129|24059520

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
13-148 3.56e-53

NADH-quinone oxidoreductase subunit NuoI;


:

Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 166.21  E-value: 3.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  13 LGGMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDDEGRERCTACGLCALACPAEAITMVASERKRGeenlyreE 92
Cdd:PRK05888   14 LKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAEREDG-------R 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2537297269  93 KYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGFIYRKDKLVESMD 148
Cdd:PRK05888   87 RRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGD 142
 
Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
13-148 3.56e-53

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 166.21  E-value: 3.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  13 LGGMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDDEGRERCTACGLCALACPAEAITMVASERKRGeenlyreE 92
Cdd:PRK05888   14 LKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAEREDG-------R 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2537297269  93 KYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGFIYRKDKLVESMD 148
Cdd:PRK05888   87 RRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGD 142
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-143 2.27e-48

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 152.57  E-value: 2.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  15 GMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDDEGRERCTACGLCALACPAEAITMVASERKRGeenlyreEKY 94
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDG-------KRR 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2537297269  95 AESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGFIYRKDKL 143
Cdd:TIGR01971  74 LKFYEINFGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 56-127 1.98e-18

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 74.40  E-value: 1.98e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2537297269  56 RERCTACGLCALACPAEAITMVASERKRgeenlyreekyaeSYEINMLRCIFCGMCEEACPKEAIFLTDRLV 127
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGK-------------VYVIDPDKCIGCGLCVEVCPTGAISMTPFEL 59
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 57-144 4.09e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 70.12  E-value: 4.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMVaserkrgeenlyREEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGF 136
Cdd:cd10549     6 EKCIGCGICVKACPTDAIELG------------PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEA 73


                  ....*...
gi 2537297269 137 IYRKDKLV 144
Cdd:cd10549    74 EIDEEKCI 81
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 59-119 5.36e-11

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 54.84  E-value: 5.36e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  59 CTACGLCALACPAEAITMVASERKRGEEnlyreekyaeSYEINMLRCIFCGMCEEACPKEA 119
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTK----------TVVIDPERCVGCGACVAVCPTGA 51
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 57-120 2.33e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.84  E-value: 2.33e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRGEenlyreekyaesyeinmlRCIFCGMCEEACPKEAI 120
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDGKPVWGH------------------NCTHCLACIHRCPKEAI 230
 
Name Accession Description Interval E-value
PRK05888 PRK05888
NADH-quinone oxidoreductase subunit NuoI;
13-148 3.56e-53

NADH-quinone oxidoreductase subunit NuoI;


Pssm-ID: 235637 [Multi-domain]  Cd Length: 164  Bit Score: 166.21  E-value: 3.56e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  13 LGGMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDDEGRERCTACGLCALACPAEAITMVASERKRGeenlyreE 92
Cdd:PRK05888   14 LKGLGVTLKYFFKKKVTIQYPEEKLPLSPRFRGRHALRRDPNGEERCIACKLCAAICPADAITIEAAEREDG-------R 86

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2537297269  93 KYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGFIYRKDKLVESMD 148
Cdd:PRK05888   87 RRTTRYDINFGRCIFCGFCEEACPTDAIVETPDFELATETREELIYDKEKLLANGD 142
NuoI TIGR01971
NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of ...
 15-143 2.27e-48

NADH-quinone oxidoreductase, chain I; This model represents the I subunit (one of 14: A->N) of the NADH-quinone oxidoreductase complex I which generally couples NADH and ubiquinone oxidation/reduction in bacteria and mammalian mitochondria, but may act on NADPH and/or plastoquinone in cyanobacteria and plant chloroplasts. This model excludes "I" subunits from the closely related F420H2 dehydrogenase and formate hydrogenlyase complexes. [Energy metabolism, Electron transport]


Pssm-ID: 273902 [Multi-domain]  Cd Length: 122  Bit Score: 152.57  E-value: 2.27e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  15 GMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDDEGRERCTACGLCALACPAEAITMVASERKRGeenlyreEKY 94
Cdd:TIGR01971   1 GLGLTLKYFFSKPVTVQYPEEKLYLPPRFRGRIVLTRDPNGEEKCIGCTLCAAVCPADAIRVVPAEGEDG-------KRR 73

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 2537297269  95 AESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGFIYRKDKL 143
Cdd:TIGR01971  74 LKFYEINFGRCIFCGLCEEACPTDAIVLTPEFELATYTRSDLVYGKEDL 122
NuoI COG1143
Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy ...
 56-127 1.98e-18

Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) [Energy production and conversion]; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440758 [Multi-domain]  Cd Length: 66  Bit Score: 74.40  E-value: 1.98e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2537297269  56 RERCTACGLCALACPAEAITMVASERKRgeenlyreekyaeSYEINMLRCIFCGMCEEACPKEAIFLTDRLV 127
Cdd:COG1143     1 EDKCIGCGLCVRVCPVDAITIEDGEPGK-------------VYVIDPDKCIGCGLCVEVCPTGAISMTPFEL 59
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 57-144 4.09e-16

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 70.12  E-value: 4.09e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMVaserkrgeenlyREEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGF 136
Cdd:cd10549     6 EKCIGCGICVKACPTDAIELG------------PNGAIARGPEIDEDKCVFCGACVEVCPTGAIELTPEGKEYVPKEKEA 73


                  ....*...
gi 2537297269 137 IYRKDKLV 144
Cdd:cd10549    74 EIDEEKCI 81
PRK12387 PRK12387
formate hydrogenlyase complex iron-sulfur subunit; Provisional
 23-124 4.74e-16

formate hydrogenlyase complex iron-sulfur subunit; Provisional


Pssm-ID: 183492 [Multi-domain]  Cd Length: 180  Bit Score: 71.22  E-value: 4.74e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  23 FFKK-----PVTTSYPEEKRDFSPVYRGRhvlkrDDEGRERCTACGLCALACPAEAITMvaserkrgEENLYREEKyaeS 97
Cdd:PRK12387    4 LIKKviktgTATSSYPLEPIAVDKNFRGK-----PEYNPQQCIGCAACVNACPSNALTV--------ETDLATGEL---A 67

                          90       100
                  ....*....|....*....|....*..
gi 2537297269  98 YEINMLRCIFCGMCEEACPKEAIFLTD 124
Cdd:PRK12387   68 WEFNLGRCIFCGRCEEVCPTAAIKLSQ 94
PRK13984 PRK13984
putative oxidoreductase; Provisional
 18-115 7.90e-15

putative oxidoreductase; Provisional


Pssm-ID: 172486 [Multi-domain]  Cd Length: 604  Bit Score: 70.95  E-value: 7.90e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  18 ITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVlkrddEGRERCTACGLCALACPAEAITMVASERKRGEENlyreeKYAES 97
Cdd:PRK13984   11 KAWKFLFRKPVTIKVPNVKREAAERYRGFHI-----NDWEKCIGCGTCSKICPTDAITMVEVPDLPQEYG-----KKPQR 80

                          90
                  ....*....|....*...
gi 2537297269  98 YEINMLRCIFCGMCEEAC 115
Cdd:PRK13984   81 PVIDYGRCSFCALCVDIC 98
PRK08222 PRK08222
hydrogenase 4 subunit H; Validated
 28-124 4.36e-14

hydrogenase 4 subunit H; Validated


Pssm-ID: 181301 [Multi-domain]  Cd Length: 181  Bit Score: 66.31  E-value: 4.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  28 VTTSYPEEKRDFSPVYRGRhvlkrDDEGRERCTACGLCALACPAEAITMVASErkrgeenlyreEKYAESYEINMLRCIF 107
Cdd:PRK08222   14 ATVKYPFAPLEVSPGFRGK-----PDLMPSQCIACGACTCACPANALTIQTDD-----------QQNSRTWQLYLGRCIY 77

                          90
                  ....*....|....*..
gi 2537297269 108 CGMCEEACPKEAIFLTD 124
Cdd:PRK08222   78 CGRCEEVCPTRAIQLTN 94
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 57-126 6.21e-12

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 59.33  E-value: 6.21e-12
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMvaserkrgEENLYREEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRL 126
Cdd:cd10549    40 DKCVFCGACVEVCPTGAIEL--------TPEGKEYVPKEKEAEIDEEKCIGCGLCVKVCPVDAITLEDEL 101
PRK08348 PRK08348
NADH-plastoquinone oxidoreductase subunit; Provisional
 24-147 9.07e-12

NADH-plastoquinone oxidoreductase subunit; Provisional


Pssm-ID: 181399 [Multi-domain]  Cd Length: 120  Bit Score: 58.69  E-value: 9.07e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  24 FKKPVTTSYPEEKRDFSPV-YRGRHVLKRDdegreRCTACGLCALACPAEAITMVASERKrgeenlyreekyaesYEINM 102
Cdd:PRK08348   13 FKKPATNLFPATEPVPVPEdFRGKILYDVD-----KCVGCRMCVTVCPAGVFVYLPEIRK---------------VALWT 72

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*..
gi 2537297269 103 LRCIFCGMCEEACPKEAIFLTDRLVMPEHLR--EGFIYRKDKLVESM 147
Cdd:PRK08348   73 GRCVFCGQCVDVCPTGALQMSDDFLLASYDRfdEKFIPLKPEKVEEI 119
ndhI CHL00014
NADH dehydrogenase subunit I
 15-130 1.52e-11

NADH dehydrogenase subunit I


Pssm-ID: 214334 [Multi-domain]  Cd Length: 167  Bit Score: 59.39  E-value: 1.52e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  15 GMKITFSHFFKKPVTTSYPEEKRDFSPVYRGRHVLKRDdegreRCTACGLCALACPAEaITMVASERKRGeenlyREEKY 94
Cdd:CHL00014   22 GFMITLSHANRLPVTIQYPYEKLITSERFRGRIHFEFD-----KCIACEVCVRVCPID-LPVVDWKLETD-----IRKKR 90

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 2537297269  95 AESYEINMLRCIFCGMCEEACPkeaiflTDRLVMPE 130
Cdd:CHL00014   91 LLNYSIDFGVCIFCGNCVEYCP------TNCLSMTE 120
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 56-120 3.89e-11

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 55.83  E-value: 3.89e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537297269  56 RERCTACGLCALACPAEAITMVaserkrgeenlyreekyAESYEINMLRCIFCGMCEEACPKEAI 120
Cdd:COG2221    14 EEKCIGCGLCVAVCPTGAISLD-----------------DGKLVIDEEKCIGCGACIRVCPTGAI 61
Fer4_7 pfam12838
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 59-119 5.36e-11

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 463724 [Multi-domain]  Cd Length: 51  Bit Score: 54.84  E-value: 5.36e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  59 CTACGLCALACPAEAITMVASERKRGEEnlyreekyaeSYEINMLRCIFCGMCEEACPKEA 119
Cdd:pfam12838   1 CIGCGACVAACPVGAITLDEVGEKKGTK----------TVVIDPERCVGCGACVAVCPTGA 51
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 56-120 8.91e-11

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 55.06  E-value: 8.91e-11
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537297269  56 RERCTACGLCALACPAEAITMvaserkrgeenlyREEKYaesYEINMLRCIFCGMCEEACPKEAI 120
Cdd:COG1144    29 EDKCIGCGLCWIVCPDGAIRV-------------DDGKY---YGIDYDYCKGCGICAEVCPVKAI 77
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 56-125 2.12e-10

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 53.58  E-value: 2.12e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  56 RERCTACGLCALACPAEAITMVASERkrgeenlyreekyaesYEINMLRCIFCGMCEEACPKEAIFLTDR 125
Cdd:COG1149    10 EEKCIGCGLCVEVCPEGAIKLDDGGA----------------PVVDPDLCTGCGACVGVCPTGAITLEER 63
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 57-123 2.32e-10

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 55.10  E-value: 2.32e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2537297269  57 ERCTACGLCALACPAEAITMvaserkrgEENLyreekyaeSYEINMLRCIFCGMCEEACPKEAIFLT 123
Cdd:cd10549    78 EKCIGCGLCVKVCPVDAITL--------EDEL--------EIVIDKEKCIGCGICAEVCPVNAIKLV 128
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 57-126 2.45e-10

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 53.89  E-value: 2.45e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMvaSERKRgeenlyreekyaesyEINMLRCIFCGMCEEACPKEAIFLTDRL 126
Cdd:COG4231    22 DKCTGCGACVKVCPADAIEE--GDGKA---------------VIDPDLCIGCGSCVQVCPVDAIKLEKRV 74
COG2768 COG2768
Uncharacterized Fe-S cluster protein [Function unknown];
57-120 3.35e-10

Uncharacterized Fe-S cluster protein [Function unknown];


Pssm-ID: 442050 [Multi-domain]  Cd Length: 74  Bit Score: 53.58  E-value: 3.35e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  57 ERCTACGLCALACPAEAITMVaserkrgeenlyreekyAESYEINMLRCIFCGMCEEACPKEAI 120
Cdd:COG2768    11 EKCIGCGACVKVCPVGAISIE-----------------DGKAVIDPEKCIGCGACIEVCPVGAI 57
PreA COG1146
NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and ...
 57-126 5.20e-10

NAD-dependent dihydropyrimidine dehydrogenase, PreA subunit [Nucleotide transport and metabolism];


Pssm-ID: 440761 [Multi-domain]  Cd Length: 67  Bit Score: 52.79  E-value: 5.20e-10
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMvaserkrgeenlyrEEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRL 126
Cdd:COG1146     8 DKCIGCGACVEVCPVDVLEL--------------DEEGKKALVINPEECIGCGACELVCPVGAITVEDDE 63
Fer4_9 pfam13187
4Fe-4S dicluster domain;
58-120 6.48e-10

4Fe-4S dicluster domain;


Pssm-ID: 463801 [Multi-domain]  Cd Length: 50  Bit Score: 52.17  E-value: 6.48e-10
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  58 RCTACGLCALACPAEAITMVASERKRgeenlyreekyaeSYEINMLRCIFCGMCEEACPKEAI 120
Cdd:pfam13187   1 KCTGCGACVAACPAGAIVPDLVGQTI-------------RGDIAGLACIGCGACVDACPRGAI 50
NapF COG1145
Ferredoxin [Energy production and conversion];
57-127 2.11e-09

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 54.73  E-value: 2.11e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERkrgeenlyreekyaeSYEINMLRCIFCGMCEEACPKEAIFLTDRLV 127
Cdd:COG1145   182 EKCIGCGLCVKVCPTGAIRLKDGKP---------------QIVVDPDKCIGCGACVKVCPVGAISLEPKEI 237
PRK06273 PRK06273
ferredoxin; Provisional
 57-160 7.34e-09

ferredoxin; Provisional


Pssm-ID: 235764 [Multi-domain]  Cd Length: 165  Bit Score: 52.02  E-value: 7.34e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRGEENLYREekyaESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLREGF 136
Cdd:PRK06273   49 ELCIGCGGCANVCPTKAIEMIPVEPVKITEGYVKT----KIPKIDYEKCVYCLYCHDFCPVFALFNEISPIHPRDVGEDI 124

                          90       100
                  ....*....|....*....|....
gi 2537297269 137 IYRKDKLVEsmdNRIDVSQRQIKK 160
Cdd:PRK06273  125 EVDVSKLLE---KPVEISEEQLSK 145
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
57-122 2.25e-08

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 52.17  E-value: 2.25e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2537297269  57 ERCTACGLCALACPAEAITMVaserkrgeenlyrEEKYAesyEINMLRCIFCGMCEEACPKEAIFL 122
Cdd:COG1148   496 EKCTGCGRCVEVCPYGAISID-------------EKGVA---EVNPALCKGCGTCAAACPSGAISL 545
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
57-124 1.04e-07

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 48.50  E-value: 1.04e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRgeenlyreekyaesyeiNMLRCIFCG------MCEEACPKEAIFLTD 124
Cdd:COG1142    81 EKCIGCGLCVLACPFGAITMVGEKSRA-----------------VAVKCDLCGgreggpACVEACPTGALRLVD 137
NapH COG0348
Polyferredoxin NapH [Energy production and conversion];
48-125 1.54e-07

Polyferredoxin NapH [Energy production and conversion];


Pssm-ID: 440117 [Multi-domain]  Cd Length: 263  Bit Score: 49.29  E-value: 1.54e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  48 VLKRDdegRERCTACGLCALACPAEAITmvaseRKRgeenlyreekyaesyEINMLRCIFCGMCEEACPKEAIFLTDR 125
Cdd:COG0348   204 RVRYD---RGDCIDCGLCVKVCPMGIDI-----RKG---------------EINQSECINCGRCIDACPKDAIRFSSR 258
Fer4_10 pfam13237
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 56-116 1.89e-07

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 404174 [Multi-domain]  Cd Length: 56  Bit Score: 45.70  E-value: 1.89e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  56 RERCTACGLCALACPAEAITMVASErkrgeenlyrEEKYAESYEINMLRCIFCGMCEEACP 116
Cdd:pfam13237   6 PDKCIGCGRCTAACPAGLTRVGAIV----------ERLEGEAVRIGVWKCIGCGACVEACP 56
Fer4_16 pfam13484
4Fe-4S double cluster binding domain;
59-116 1.91e-07

4Fe-4S double cluster binding domain;


Pssm-ID: 463893 [Multi-domain]  Cd Length: 65  Bit Score: 45.94  E-value: 1.91e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  59 CTACGLCALACPAEAITMVAS--ERKRGEENLYREEKYAESYEINML---RCIFCGMCEEACP 116
Cdd:pfam13484   1 CGSCGKCIDACPTGAIVGPEGvlDARRCISYLTIEKKGLIPDELRCLlgnRCYGCDICQDVCP 63
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
59-120 2.27e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 48.78  E-value: 2.27e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2537297269  59 CTACGLCALACPAEAITMvaserkrgEENLyreekyaesYEINMLRCIFCGMCEEACPKEAI 120
Cdd:PRK07118  215 CIGCGKCVKACPAGAITM--------ENNL---------AVIDQEKCTSCGKCVEKCPTKAI 259
PRK07118 PRK07118
Fe-S cluster domain-containing protein;
56-131 2.60e-07

Fe-S cluster domain-containing protein;


Pssm-ID: 235941 [Multi-domain]  Cd Length: 280  Bit Score: 48.78  E-value: 2.60e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2537297269  56 RERCTACGLCALACPAEAITMV-ASERKRGEENlyREEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEH 131
Cdd:PRK07118  167 EDKCTGCGACVKACPRNVIELIpKSARVFVACN--SKDKGKAVKKVCEVGCIGCGKCVKACPAGAITMENNLAVIDQ 241
Fer4_8 pfam13183
4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to ...
 58-117 7.92e-07

4Fe-4S dicluster domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.


Pssm-ID: 433017 [Multi-domain]  Cd Length: 64  Bit Score: 44.22  E-value: 7.92e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  58 RCTACGLCALACP---AEAITMVASERKRGEENLYREEKYAESYEInMLRCIFCGMCEEACPK 117
Cdd:pfam13183   1 RCIRCGACLAACPvylVTGGRFPGDPRGGAAALLGRLEALEGLAEG-LWLCTLCGACTEVCPV 62
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 49-122 1.65e-06

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 45.07  E-value: 1.65e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  49 LKRDDEG-----RERCTACGLCALACPAEAITMVASERKrgeenlyreekyaesyeinMLRCIFCG---------MCEEA 114
Cdd:cd04410    67 IYKDEDGivlidEDKCIGCGSCVEACPYGAIVFDPEPGK-------------------AVKCDLCGdrldeglepACVKA 127


                  ....*...
gi 2537297269 115 CPKEAIFL 122
Cdd:cd04410   128 CPTGALTF 135
DMSOR_beta_like cd16372
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 59-129 2.15e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319894 [Multi-domain]  Cd Length: 125  Bit Score: 44.63  E-value: 2.15e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  59 CTACGLCALACPAEAITmvasERKRGeenlyreekyaeSYEINMLRCIFCGMCEEACPKEAIFLTDRLVMP 129
Cdd:cd16372    49 CNQCGECIDVCPTGAIT----RDANG------------VVMINKKLCVGCLMCVGFCPEGAMFKHEDYPEP 103
ACS_1 cd01916
Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and ...
 50-118 2.29e-06

Acetyl-CoA synthase (ACS), also known as acetyl-CoA decarbonylase, is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA. ACS forms a heterotetramer with carbon monoxide dehydrogenase (CODH) consisting of two ACS and two CODH subunits. CODH reduces carbon dioxide to carbon monoxide and ACS then synthesizes acetyl-CoA from carbon monoxide, CoA, and a methyl group donated by another protein (CoFeSP). ACS has three structural domains, an N-terminal rossman fold domain with a helical region at its N-terminus which interacts with CODH, and two alpha + beta fold domains. A Ni-Fe-S center referred to as the A-cluster is located in the C-terminal domain. A large cavity exists between the three domains which may bind CoA.


Pssm-ID: 238897 [Multi-domain]  Cd Length: 731  Bit Score: 46.25  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  50 KRDDEGRE-----------RCTACGLCALACPaEAITMVASERKRGEENLyreEKYAESYEinmlRCIFCGMCEEACPKE 118
Cdd:cd01916   347 KRKGEKKLptdeefqelaaKCTDCGWCTRACP-NSLRIKEAMEAAKEGDF---SGLADLFD----QCVGCGRCEQECPKE 418
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 49-120 8.85e-06

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 42.95  E-value: 8.85e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  49 LKRDDEGR------ERCTACGLCALACPAEAITMVASERKrgeenlyreekyaesyeinMLRCIFCG---MCEEACPKEA 119
Cdd:cd10550    66 ISRDEETGavvvdeDKCIGCGMCVEACPFGAIRVDPETGK-------------------AIKCDLCGgdpACVKVCPTGA 126


                  .
gi 2537297269 120 I 120
Cdd:cd10550   127 L 127
Nar1 COG4624
Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];
56-120 1.61e-05

Iron only hydrogenase large subunit, C-terminal domain [Energy production and conversion];


Pssm-ID: 443663 [Multi-domain]  Cd Length: 450  Bit Score: 43.86  E-value: 1.61e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537297269  56 RERCTACGLCALACPAEAITMvaserkrgeenlyrEEKYAEsyeINMLRCIFCGMCEEACPKEAI 120
Cdd:COG4624    90 KEKCKNCYPCVRACPVKAIKV--------------DDGKAE---IDEEKCISCGQCVAVCPFGAI 137
GlpC COG0247
Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy ...
 57-116 1.69e-05

Fe-S cluster-containing oxidoreductase, includes glycolate oxidase subunit GlcF [Energy production and conversion];


Pssm-ID: 440017 [Multi-domain]  Cd Length: 420  Bit Score: 43.53  E-value: 1.69e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRGEENLYRE--------EKYAESYEInMLRCIFCGMCEEACP 116
Cdd:COG0247    78 DACVGCGFCRAMCPSYKATGDEKDSPRGRINLLREvlegelplDLSEEVYEV-LDLCLTCKACETACP 144
RnfB COG2878
Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and ...
 56-126 1.73e-05

Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit [Energy production and conversion]; Na+-translocating ferredoxin:NAD+ oxidoreductase RNF, RnfB subunit is part of the Pathway/BioSystem: Na+-translocating Fd:NADH oxidoreductase


Pssm-ID: 442125 [Multi-domain]  Cd Length: 254  Bit Score: 43.44  E-value: 1.73e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  56 RERCTACGLCALACPAEAITMVASERKRGEENLYREEKYAESYEinmlrCIfcGMCEEACPKEAIFLTDRL 126
Cdd:COG2878   166 EDKCTGCGLCVEACPVDCIEMVPVSPTVVVSSWDKGKAVRKVVG-----CI--GLCCKKCCPAAAITVNNL 229
oorD PRK09626
2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed
 58-125 2.20e-05

2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed


Pssm-ID: 236597 [Multi-domain]  Cd Length: 103  Bit Score: 41.24  E-value: 2.20e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2537297269  58 RCTACGLCALACPAEAITMVA-SERKRGEenlYREEKYAESyeinmlrCIFCGMCEEACPKEAIFLTDR 125
Cdd:PRK09626   17 RCKACDICVSVCPAGVLAMRIdPHAVLGK---MIKVVHPES-------CIGCRECELHCPDFAIYVADR 75
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 47-122 2.56e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 41.79  E-value: 2.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  47 HVLKRDDEGRER---CTACG--LCALACPAEAITmvaserkRGEENlyreekyaESYEINMLRCIFCGMCEEACPKEAIF 121
Cdd:cd10550    34 RVVRFEPEGLDVpvvCRQCEdaPCVEACPVGAIS-------RDEET--------GAVVVDEDKCIGCGMCVEACPFGAIR 98


                  .
gi 2537297269 122 L 122
Cdd:cd10550    99 V 99
PRK13795 PRK13795
hypothetical protein; Provisional
 58-116 3.15e-05

hypothetical protein; Provisional


Pssm-ID: 237510 [Multi-domain]  Cd Length: 636  Bit Score: 43.06  E-value: 3.15e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 2537297269  58 RCTACGLCALACPAEAITMVASERKrgeenlyreekyaesYEINMLRCIFCGMCEEACP 116
Cdd:PRK13795  582 ECVGCGVCVGACPTGAIRIEEGKRK---------------ISVDEEKCIHCGKCTEVCP 625
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 57-125 4.89e-05

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 41.08  E-value: 4.89e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  57 ERCTACGLCALACPAEAItmvaserKRGEENLyreekyaesYEINMLR--CIFCGMCEEACPkEAIFLTDR 125
Cdd:cd10564    13 DLCTRCGDCVEACPEGII-------VRGDGGF---------PELDFSRgeCTFCGACAEACP-EGALDPAR 66
PorD COG1144
Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta ...
 48-77 6.39e-05

Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit [Energy production and conversion]; Pyruvate:ferredoxin oxidoreductase or related 2-oxoacid:ferredoxin oxidoreductase, delta subunit is part of the Pathway/BioSystem: Pyruvate oxidation


Pssm-ID: 440759 [Multi-domain]  Cd Length: 84  Bit Score: 39.65  E-value: 6.39e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 2537297269  48 VLKRDDEGR-----ERCTACGLCALACPAEAITMV 77
Cdd:COG1144    46 AIRVDDGKYygidyDYCKGCGICAEVCPVKAIEMV 80
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 57-85 6.85e-05

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 39.33  E-value: 6.85e-05
                          10        20
                  ....*....|....*....|....*....
gi 2537297269  57 ERCTACGLCALACPAEAITMVasERKRGE 85
Cdd:COG1149    41 DLCTGCGACVGVCPTGAITLE--EREAGK 67
PsrB cd10551
polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial ...
 51-121 7.20e-05

polysulfide reductase beta (PsrB) subunit; This family includes the beta subunit of bacterial polysulfide reductase (PsrABC), an integral membrane-bound enzyme responsible for quinone-coupled reduction of polysulfides, a process important in extreme environments such as deep-sea vents and hot springs. Polysulfide reductase contains three subunits: a catalytic subunit PsrA, an electron transfer PsrB subunit and the hydrophobic transmembrane PsrC subunit. PsrB belongs to the DMSO reductase superfamily that contains [4Fe-4S] clusters which transfer the electrons from the A subunit to the hydrophobic integral membrane C subunit via the B subunit. In Shewanella oneidensis, which has highly diverse anaerobic respiratory pathways, PsrABC is responsible for H2S generation as well as its regulation via respiration of sulfur species. PsrB transfers electrons from PsrC (serving as quinol oxidase) to the catalytic subunit PsrA for reduction of corresponding electron acceptors. It has been shown that T. thermophilus polysulfide reductase could be a key energy-conserving enzyme of the respiratory chain, using polysulfide as the terminal electron acceptor and pumping protons across the membrane.


Pssm-ID: 319873 [Multi-domain]  Cd Length: 185  Bit Score: 40.98  E-value: 7.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  51 RDDEG-----RERCTACGLCALACPAEAITMVASERKRGEENLYREEKYAESyeinmlrCIFC------GM---CEEACP 116
Cdd:cd10551    72 KREDGivlvdYDKCIGCRYCMAACPYGARYFNPEEPHEFGEVPVRPKGVVEK-------CTFCyhrldeGLlpaCVEACP 144


                  ....*
gi 2537297269 117 KEAIF 121
Cdd:cd10551   145 TGARI 149
DMSOR_beta_like cd10550
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 56-120 9.68e-05

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319872 [Multi-domain]  Cd Length: 130  Bit Score: 39.87  E-value: 9.68e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  56 RERCTACGLCALACpaeaitmvaSERKRGEENLY----REEKYAESYEINMLRCIFCG--MCEEACPKEAI 120
Cdd:cd10550     5 PEKCTGCRTCELAC---------SLKHEGVFNPSlsriRVVRFEPEGLDVPVVCRQCEdaPCVEACPVGAI 66
PRK12576 PRK12576
succinate dehydrogenase/fumarate reductase iron-sulfur subunit;
59-118 1.04e-04

succinate dehydrogenase/fumarate reductase iron-sulfur subunit;


Pssm-ID: 237143 [Multi-domain]  Cd Length: 279  Bit Score: 41.27  E-value: 1.04e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  59 CTACGLCALACPAEAIT---MVASERKRGEENLY--REEKYAESYEINM---LRCIFCGMCEEACPKE 118
Cdd:PRK12576  154 CIWCGLCVSACPVVAIDpefLGPAAHAKGYRFLAdpRDTITEERMKILIdssWRCTYCYSCSNVCPRD 221
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 57-120 1.05e-04

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 41.40  E-value: 1.05e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLC------ALACPAEAITMVASERKrgeenlyreekyaesYEINMLRCIFCGMCEEACPKEAI 120
Cdd:PRK12771  504 ARCLSCGNCfecdncYGACPQDAIIKLGPGRR---------------YHFDYDKCTGCHICADVCPCGAI 558
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 98-120 1.09e-04

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 37.61  E-value: 1.09e-04
                          10        20
                  ....*....|....*....|...
gi 2537297269  98 YEINMLRCIFCGMCEEACPKEAI 120
Cdd:pfam00037   1 VVIDEEKCIGCGACVEVCPVGAI 23
Fer4_17 pfam13534
4Fe-4S dicluster domain; This family includes proteins containing domains which bind to ...
 58-118 1.22e-04

4Fe-4S dicluster domain; This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 433287 [Multi-domain]  Cd Length: 61  Bit Score: 38.21  E-value: 1.22e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  58 RCTACGLCALACPAEAITmvASERKRGEENLYREEKYAESYEINMLRCIFCGMCEEACPKE 118
Cdd:pfam13534   1 RCIQCGCCVDECPRYLLN--GDEPKKLMRAAYLGDLEELQANKVANLCSECGLCEYACPMG 59
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 56-116 1.41e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 39.93  E-value: 1.41e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2537297269  56 RERC------TACGLCALACPAEAITMVaserkrgeenLYREEKYAEsyeINMLRCIFCGMCEEACP 116
Cdd:cd16373    90 KDRClawqggTDCGVCVEACPTEAIAIV----------LEDDVLRPV---VDEDKCVGCGLCEYVCP 143
napF TIGR00402
ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of ...
 29-121 1.62e-04

ferredoxin-type protein NapF; The gene codes for a ferredoxin-type cytosolic protein, NapF, of the periplasmic nitrate reductase system, as in Escherichia coli. NapF interacts with the catalytic subunit, NapA, and may be an accessory protein for NapA maturation. [Energy metabolism, Electron transport]


Pssm-ID: 273060 [Multi-domain]  Cd Length: 101  Bit Score: 38.77  E-value: 1.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  29 TTSYPEEKRDFSPVYRGRhvlkrDDEGRERCTACGLCALACPAEAITmvaserkrgeenlyREEKYAESYEINMLRCIFC 108
Cdd:TIGR00402  11 ATSSTIEKTQIRPPWSAR-----ESLFSAVCTRCGECASACENNILQ--------------LGQQGQPTVEFDNAECDFC 71

                          90
                  ....*....|...
gi 2537297269 109 GMCEEACPKEAIF 121
Cdd:TIGR00402  72 GKCAEACPTNAFH 84
HycB_like cd10554
HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a ...
 57-120 1.67e-04

HycB, HydN and similar proteins; This family includes HycB, the FeS subunit of a membrane-associated formate hydrogenlyase system (FHL-1) in Escherichia coli that breaks down formate, produced during anaerobic fermentation, to H2 and CO2. FHL-1 consists of formate dehydrogenase H (FDH-H) and the hydrogenase 3 complex (Hyd-3). HycB is thought to code for the [4Fe-4S] ferredoxin subunit of hydrogenase 3, which functions as an intermediate electron carrier protein between hydrogenase 3 and formate dehydrogenase. HydN codes for the [4Fe-4S] ferredoxin subunit of FDH-H; a hydN in-frame deletion mutation causes only weak reduction in hydrogenase activity, but loss of more than 60% of FDH-H activity. This pathway is only active at low pH and high formate concentrations, and is thought to provide a detoxification/de-acidification system countering the buildup of formate during fermentation.


Pssm-ID: 319876 [Multi-domain]  Cd Length: 149  Bit Score: 39.55  E-value: 1.67e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMVaSERKRGEENLYREEKYAesyeinmLRCIFCG------MCEEACPKEAI 120
Cdd:cd10554    85 ERCIGCKLCVLACPFGAIEMA-PTTVPGVDWERGPRAVA-------VKCDLCAgreggpACVEACPTKAL 146
HybA COG0437
Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and ...
 49-125 2.12e-04

Fe-S-cluster-containing dehydrogenase component (DMSO reductase) [Energy production and conversion];


Pssm-ID: 440206 [Multi-domain]  Cd Length: 184  Bit Score: 39.93  E-value: 2.12e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  49 LKRDDEG-----RERCTACGLCALACPAEAITMVASERKrgeenlyreekyaesyeinMLRCIFCG---------MCEEA 114
Cdd:COG0437    77 TYKREDGivlvdYDKCIGCRYCVAACPYGAPRFNPETGV-------------------VEKCTFCAdrldegllpACVEA 137

                          90
                  ....*....|.
gi 2537297269 115 CPKEAIFLTDR 125
Cdd:COG0437   138 CPTGALVFGDL 148
NapF_like cd10564
NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, ...
 57-78 2.19e-04

NapF, iron-sulfur subunit of periplasmic nitrate reductase; This family contains NapF protein, the iron-sulfur subunit of periplasmic nitrate reductase. The periplasmic nitrate reductase NapABC of Escherichia coli likely functions during anaerobic growth in low-nitrate environments; napF operon expression is activated by cyclic AMP receptor protein (Crp). NapF is a subfamily of the beta subunit of DMSO reductase (DMSOR) family. DMSOR family members have a large, periplasmic molybdenum-containing alpha subunit as well as a small beta FeS subunit, and may also have a small gamma subunit. The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319886 [Multi-domain]  Cd Length: 139  Bit Score: 39.15  E-value: 2.19e-04
                          10        20
                  ....*....|....*....|..
gi 2537297269  57 ERCTACGLCALACPAEAITMVA 78
Cdd:cd10564   117 DACTGCGACVSVCPVGAITLTP 138
ferrodoxin_EFR1 NF038196
EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight ...
 57-120 2.33e-04

EFR1 family ferrodoxin; Members of the family have a C-terminal ferrodoxin domain, with eight conserved Cys residues in two CxxCxxCxxxCP motifs, each of which binds a 4Fe-4S cluster. The N-terminal region resembles flavodoxin domains, with some members of the family recognized by Pfam models PF12724 (Flavodoxin_5) or PF00258 (Flavodoxin_1).


Pssm-ID: 468407 [Multi-domain]  Cd Length: 243  Bit Score: 39.84  E-value: 2.33e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRGEenlyreekyaesyeinmlRCIFCGMCEEACPKEAI 120
Cdd:NF038196  185 DKCIGCGICAKVCPVNNIEMEDGKPVWGH------------------NCTHCLACIHRCPKEAI 230
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 56-131 2.54e-04

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 38.91  E-value: 2.54e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  56 RERCTACG--LCALACPAEAItmvaSERKRGEenlyreekyaesYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEH 131
Cdd:cd04410    47 PVSCMHCEdpPCVKACPTGAI----YKDEDGI------------VLIDEDKCIGCGSCVEACPYGAIVFDPEPGKAVK 108
PRK09326 PRK09326
F420H2 dehydrogenase subunit F; Provisional
 59-126 3.76e-04

F420H2 dehydrogenase subunit F; Provisional


Pssm-ID: 181779 [Multi-domain]  Cd Length: 341  Bit Score: 39.82  E-value: 3.76e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  59 CTACGLCALACPAEAITMVASERKRGEENLYREEKYAeSYEInmlrCIFCGMCEEACPKEAIFLTDRL 126
Cdd:PRK09326   14 CTACGACEAVCPIGAITVDKKAEIRDPNDLELYEKGA-APNV----CEGCLTCSRICPVVDGYIEDEL 76
COG1453 COG1453
Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];
59-116 3.99e-04

Predicted oxidoreductase of the aldo/keto reductase family [General function prediction only];


Pssm-ID: 441062 [Multi-domain]  Cd Length: 365  Bit Score: 39.42  E-value: 3.99e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2537297269  59 CTACGLCaLACPAEA-ITMVAseRKRGEENLYREEKYAeSYEINML-------RCIFCGMCEEACP 116
Cdd:COG1453   283 CTGCGYC-MPCPQGInIPEVF--RLYNLARAYGMREYA-KERYNALgpgakasACIECGACEERCP 344
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 58-120 4.06e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 38.78  E-value: 4.06e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2537297269  58 RCTACGLCALACPAEAITMVASErkRGEENLYR-----EEKYaesyeinmlrCIFCG-MCEEACPKEAI 120
Cdd:cd16373    15 LCIRCGLCVEACPTGVIQPAGLE--DGLEGGRTpyldpREGP----------CDLCCdACVEVCPTGAL 71
DMSOR_beta_like cd16374
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 49-125 4.47e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319896 [Multi-domain]  Cd Length: 139  Bit Score: 38.41  E-value: 4.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  49 LKRDDEGR-----ERCTACGLCALACPAEAITMVASERKrgeenlyreekyaesyeinMLRCIFCG---------MCEEA 114
Cdd:cd16374    60 IYRDEDGAvlvdpDKCIGCGMCAMACPFGVPRFDPSLKV-------------------AVKCDLCIdrrregklpACVEA 120

                          90
                  ....*....|.
gi 2537297269 115 CPKEAIFLTDR 125
Cdd:cd16374   121 CPTGALKFGDI 131
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 56-120 4.60e-04

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 38.02  E-value: 4.60e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2537297269  56 RERCTACGLCALACPAEAITMVASERKrgeenlyreekyaesyeinMLRCIFCGMCEEACPKEAI 120
Cdd:cd16370    82 KEKCIGCGNCVKACIVGAIFWDEETNK-------------------PIICIHCGYCARYCPHDVL 127
PRK14028 PRK14028
pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional
 58-120 5.69e-04

pyruvate ferredoxin oxidoreductase subunit gamma/delta; Provisional


Pssm-ID: 172522 [Multi-domain]  Cd Length: 312  Bit Score: 39.21  E-value: 5.69e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  58 RCTACGLCALACPAEAITMVASERKRGEENLYREEKYAESYEInmlrCIFCGMCEEACPKEAI 120
Cdd:PRK14028  248 KCIMCRKCWLYCPDDAIIEAWREAEGPRGRKFRMKMIDFDYQY----CKGCGVCAEVCPTGAI 306
Fer4 pfam00037
4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to ...
 57-75 1.08e-03

4Fe-4S binding domain; Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.


Pssm-ID: 459642 [Multi-domain]  Cd Length: 24  Bit Score: 34.92  E-value: 1.08e-03
                          10
                  ....*....|....*....
gi 2537297269  57 ERCTACGLCALACPAEAIT 75
Cdd:pfam00037   6 EKCIGCGACVEVCPVGAIT 24
DMSOR_beta-like cd04410
Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta ...
 57-124 1.15e-03

Beta subunit of the DMSO Reductase (DMSOR) family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319870 [Multi-domain]  Cd Length: 136  Bit Score: 37.37  E-value: 1.15e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  57 ERCTACGLCALACPAEAITMVASERKRGEenlYREEKYAESYEINMlRCIFCG--MCEEACPKEAIFLTD 124
Cdd:cd04410     6 DRCIGCGTCEVACKQEHGLRPGPDWSRIK---VIEGGGLERAFLPV-SCMHCEdpPCVKACPTGAIYKDE 71
SIMIBI_bact_arch cd03110
bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily ...
 56-127 1.40e-03

bacterial and archaeal subfamily of SIMIBI; Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.


Pssm-ID: 349764 [Multi-domain]  Cd Length: 246  Bit Score: 37.75  E-value: 1.40e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2537297269  56 RERCTACGLCALACPAEAITmvaserkrgeenlyreeKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLV 127
Cdd:cd03110    63 QEKCIRCGNCERVCKFGAIL-----------------EFFQKLIVDESLCEGCGACVIICPRGAIYLKDRDT 117
HycB COG1142
Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];
59-125 1.44e-03

Fe-S-cluster-containing hydrogenase component 2 [Energy production and conversion];


Pssm-ID: 440757 [Multi-domain]  Cd Length: 138  Bit Score: 36.94  E-value: 1.44e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2537297269  59 CTACGL--CALACPAEAITmvaseRKRGEENLYREekyaesyeinmlRCIFCGMCEEACPKEAIFLTDR 125
Cdd:COG1142    52 CRHCEDapCAEVCPVGAIT-----RDDGAVVVDEE------------KCIGCGLCVLACPFGAITMVGE 103
SdhB/FrdB COG0479
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and ...
 20-118 1.58e-03

Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit is part of the Pathway/BioSystem: TCA cycle


Pssm-ID: 440247 [Multi-domain]  Cd Length: 230  Bit Score: 37.42  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  20 FSHFFKK--------PVTTSYPEEKRDFSPvyrgrHVLKRDDEGRErCTACGLCALACPAEAIT--------MVASER-- 81
Cdd:COG0479   103 RSAFFDKlkkvkpylSPDGPAPDNERLQSP-----EDREKADDLAE-CILCGACVAACPNVWANpdflgpaaLAQAYRfa 176

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 2537297269  82 --KRGEENLYREEKYAESYEINmlRCIFCGMCEEACPKE 118
Cdd:COG0479   177 ldPRDEETEERLEALEDEEGVW--RCTTCGNCTEVCPKG 213
IorA COG4231
TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and ...
 95-128 1.65e-03

TPP-dependent indolepyruvate ferredoxin oxidoreductase, alpha subunit [Energy production and conversion];


Pssm-ID: 443375 [Multi-domain]  Cd Length: 76  Bit Score: 35.40  E-value: 1.65e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2537297269  95 AESYEINMLRCIFCGMCEEACPKEAIFLTDRLVM 128
Cdd:COG4231    14 AMRYVIDEDKCTGCGACVKVCPADAIEEGDGKAV 47
RDH TIGR02486
reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S ...
 56-116 1.78e-03

reductive dehalogenase; This model represents a family of corrin and 8-iron Fe-S cluster-containing reductive dehalogenases found primarily in halorespiring microorganisms such as dehalococcoides ethenogenes which contains as many as 17 enzymes of this type with varying substrate ranges. One example of a characterized species is the tetrachloroethene reductive dehalogenase (1.97.1.8) which also acts on trichloroethene converting it to dichloroethene.


Pssm-ID: 274158  Cd Length: 314  Bit Score: 37.80  E-value: 1.78e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  56 RERCTACGLCALACPAEAITMV---------ASERKRGEENLYREEKY----AESYEINMLRCIFCGMCEEACP 116
Cdd:TIGR02486 204 AKFCETCGKCADECPSGAISKGgeptwdpedSNGDPPGENNPGLKWQYdgwrCLLFRCYNEGGGGCGVCQAVCP 277
HdrA COG1148
Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];
61-128 1.81e-03

Heterodisulfide reductase, subunit A (polyferredoxin) [Energy production and conversion];


Pssm-ID: 440762 [Multi-domain]  Cd Length: 563  Bit Score: 37.92  E-value: 1.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  61 ACGLC------------ALACPAEAITMVASErkrgeeNLYREEKYAEsyeINMLRCIFCGMCEEACPKEAIFLTDRLVM 128
Cdd:COG1148   451 LAGAAhgpkdipesiaqATAAAARAIQLLSKG------ELGVEPSVAE---VDPEKCTGCGRCVEVCPYGAISIDEKGVA 521
NapF COG1145
Ferredoxin [Energy production and conversion];
61-134 2.00e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 37.39  E-value: 2.00e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2537297269  61 ACGLCALACPAEAITMVASERKRGEENLYREEKYAESYEINMLRCIFCGMCEEACPKEAIFLTDRLVMPEHLRE 134
Cdd:COG1145   140 AEAGLAILGAAAPVDALAISGGKKIEEELKIAIKKAKAVIDAEKCIGCGLCVKVCPTGAIRLKDGKPQIVVDPD 213
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 99-124 2.22e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 35.03  E-value: 2.22e-03
                          10        20
                  ....*....|....*....|....*.
gi 2537297269  99 EINMLRCIFCGMCEEACPKEAIFLTD 124
Cdd:COG2221    11 KIDEEKCIGCGLCVAVCPTGAISLDD 36
PRK08318 PRK08318
NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;
56-88 2.25e-03

NAD-dependent dihydropyrimidine dehydrogenase subunit PreA;


Pssm-ID: 236237 [Multi-domain]  Cd Length: 420  Bit Score: 37.23  E-value: 2.25e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 2537297269  56 RERCTACGLCALACPAE-AITMVASERKRGEENL 88
Cdd:PRK08318  376 EEECVGCNLCAHVCPVEgCITMGEVKFGKPYANW 409
PRK09898 PRK09898
ferredoxin-like protein;
58-120 2.52e-03

ferredoxin-like protein;


Pssm-ID: 182135 [Multi-domain]  Cd Length: 208  Bit Score: 36.74  E-value: 2.52e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  58 RCTACGLCALACPAEAITMVASERKRGeenlyreekyaesyeinmlRCIFCGMCEEACPKEAI 120
Cdd:PRK09898  155 RCIGCSACTTACPWMMATVNTESKKSS-------------------KCVLCGECANACPTGAL 198
COG1149 COG1149
MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function ...
 98-124 2.82e-03

MinD superfamily P-loop ATPase, contains an inserted ferredoxin domain [General function prediction only];


Pssm-ID: 440763 [Multi-domain]  Cd Length: 68  Bit Score: 34.70  E-value: 2.82e-03
                          10        20
                  ....*....|....*....|....*..
gi 2537297269  98 YEINMLRCIFCGMCEEACPKEAIFLTD 124
Cdd:COG1149     6 PVIDEEKCIGCGLCVEVCPEGAIKLDD 32
MtMvhB_like cd10549
Uncharacterized polyferredoxin-like protein; This family contains uncharacterized ...
 99-131 3.68e-03

Uncharacterized polyferredoxin-like protein; This family contains uncharacterized polyferredoxin protein similar to Methanobacterium thermoautotrophicum MvhB. The mvhB is a gene of the methylviologen-reducing hydrogenase operon. It is predicted to contain 12 [4Fe-4S] clusters, and was therefore suggested to be a polyferredoxin. As a subfamily of the beta subunit of the DMSO Reductase (DMSOR) family, it is predicted to function as electron carrier in the reducing reaction.


Pssm-ID: 319871 [Multi-domain]  Cd Length: 128  Bit Score: 35.84  E-value: 3.68e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2537297269  99 EINMLRCIFCGMCEEACPKEAIFLTDRLVMPEH 131
Cdd:cd10549     2 KYDPEKCIGCGICVKACPTDAIELGPNGAIARG 34
napG PRK09476
quinol dehydrogenase periplasmic component; Provisional
 62-135 3.73e-03

quinol dehydrogenase periplasmic component; Provisional


Pssm-ID: 236534 [Multi-domain]  Cd Length: 254  Bit Score: 36.53  E-value: 3.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  62 CGLCALACPA--EAITMvasERKRGEenlyREEKYAesyeinMLR-------CIFCGMCEEAC--PKEAIFltdrlVMPE 130
Cdd:PRK09476  147 CDVCYRVCPLidKAITL---ELERNE----RTGKHA------FFLptvhsdaCTGCGKCEKACvlEKAAIK-----VLPR 208


                  ....*
gi 2537297269 131 HLREG 135
Cdd:PRK09476  209 SLAKG 213
DMSOR_beta_like cd16370
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 59-129 3.84e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319892 [Multi-domain]  Cd Length: 131  Bit Score: 35.71  E-value: 3.84e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2537297269  59 CTACGL--CALACPAEAITmvasERKRGEENLYREekyaesyeinmlRCIFCGMCEEACPKEAIFLTDRLVMP 129
Cdd:cd16370    53 CRACEDppCAEACPTGALE----PRKGGGVVLDKE------------KCIGCGNCVKACIVGAIFWDEETNKP 109
vorD PRK09623
3-methyl-2-oxobutanoate dehydrogenase subunit delta;
59-81 4.38e-03

3-methyl-2-oxobutanoate dehydrogenase subunit delta;


Pssm-ID: 170016 [Multi-domain]  Cd Length: 105  Bit Score: 34.92  E-value: 4.38e-03
                          10        20
                  ....*....|....*....|...
gi 2537297269  59 CTACGLCALACPAEAITMVASER 81
Cdd:PRK09623   83 CKGCGICANECPTKAITMVKEEK 105
PRK12809 PRK12809
putative oxidoreductase Fe-S binding subunit; Reviewed
 31-126 4.39e-03

putative oxidoreductase Fe-S binding subunit; Reviewed


Pssm-ID: 183762 [Multi-domain]  Cd Length: 639  Bit Score: 36.54  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  31 SYPEEKRDFSPvyRGRHVLKRDDEGRERCTAC--GLCALACPAEAITMVAserkrgeenlyreekyaESYEINMLRCIFC 108
Cdd:PRK12809   30 NWPLSHSDFRP--RIHVVGKGQAANPVACHHCnnAPCVTACPVNALTFQS-----------------DSVQLDEQKCIGC 90

                          90
                  ....*....|....*...
gi 2537297269 109 GMCEEACPKEAIFLTDRL 126
Cdd:PRK12809   91 KRCAIACPFGVVEMVDTI 108
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 36-115 5.05e-03

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 36.27  E-value: 5.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2537297269  36 KRDFSPVYRGRHVLKRDDEGrERCTACGL--CALACPA-----EAITMVAserkrgeenlyrEEKYAESYEINMLRCIF- 107
Cdd:COG0493     2 IKDFREVYPGLSEEEAIEQA-ARCLDCGDppCQTGCPVgndipEWIRLIA------------EGDYEEALELIHETNPFp 68

                          90
                  ....*....|....*
gi 2537297269 108 --CGM-----CEEAC 115
Cdd:COG0493    69 evCGRvcpapCEGAC 83
DsrA COG2221
Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion ...
 57-75 5.35e-03

Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits [Inorganic ion transport and metabolism];


Pssm-ID: 441823 [Multi-domain]  Cd Length: 69  Bit Score: 33.87  E-value: 5.35e-03
                          10
                  ....*....|....*....
gi 2537297269  57 ERCTACGLCALACPAEAIT 75
Cdd:COG2221    44 EKCIGCGACIRVCPTGAIK 62
PRK12771 PRK12771
putative glutamate synthase (NADPH) small subunit; Provisional
 50-80 5.52e-03

putative glutamate synthase (NADPH) small subunit; Provisional


Pssm-ID: 237198 [Multi-domain]  Cd Length: 564  Bit Score: 36.39  E-value: 5.52e-03
                          10        20        30
                  ....*....|....*....|....*....|.
gi 2537297269  50 KRDDEGRERCTACGLCALACPAEAITMVASE 80
Cdd:PRK12771  534 RRYHFDYDKCTGCHICADVCPCGAIEMGPGE 564
PRK10330 PRK10330
electron transport protein HydN;
56-125 6.66e-03

electron transport protein HydN;


Pssm-ID: 182382 [Multi-domain]  Cd Length: 181  Bit Score: 35.64  E-value: 6.66e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2537297269  56 RERCTACGLCALACPAEAITMVASE--RKRGEENLYREEKyAESYeinmlRCIFCG------MCEEACPKEAIFLTDR 125
Cdd:PRK10330   86 QERCIGCKTCVVACPYGAMEVVVRPviRNSGAGLNVRAEK-AEAN-----KCDLCNhredgpACMAACPTHALICVDR 157
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 59-116 7.59e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 36.08  E-value: 7.59e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2537297269  59 CTACGLCALACPAE---------AitmvaserkRGEENlyreEKyAESYeiNMLRCIFCGMCEEACP 116
Cdd:PRK05035  372 CIRCGACADACPASllpqqlywfA---------KAEEH----DK-AQEY--NLFDCIECGACAYVCP 422
NapF COG1145
Ferredoxin [Energy production and conversion];
56-80 8.15e-03

Ferredoxin [Energy production and conversion];


Pssm-ID: 440760 [Multi-domain]  Cd Length: 238  Bit Score: 35.47  E-value: 8.15e-03
                          10        20
                  ....*....|....*....|....*
gi 2537297269  56 RERCTACGLCALACPAEAITMVASE 80
Cdd:COG1145   212 PDKCIGCGACVKVCPVGAISLEPKE 236
DMSOR_beta_like cd16373
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 59-125 8.16e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319895 [Multi-domain]  Cd Length: 154  Bit Score: 34.92  E-value: 8.16e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2537297269  59 CTACG-LCALACPAEAITMVASERKR---GEENLYREEKYAESYEInmlrciFCGMCEEACPKEAIFLTDR 125
Cdd:cd16373    55 CDLCCdACVEVCPTGALRPLDLEEQKvkmGVAVIDKDRCLAWQGGT------DCGVCVEACPTEAIAIVLE 119
DMSOR_beta_like cd16367
uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the ...
 49-77 9.81e-03

uncharacterized subfamily of DMSO Reductase beta subunit family; This family consists of the small beta iron-sulfur (FeS) subunit of the DMSO Reductase (DMSOR) family. Members of this family also contain a large, periplasmic molybdenum-containing alpha subunit and may have a small gamma subunit as well. Examples of heterodimeric members with alpha and beta subunits include arsenite oxidase, and tungsten-containing formate dehydrogenase (FDH-T) while heterotrimeric members containing alpha, beta, and gamma subunits include formate dehydrogenase-N (FDH-N), and nitrate reductase (NarGHI). The beta subunit contains four Fe4/S4 and/or Fe3/S4 clusters which transfer the electrons from the alpha subunit to a hydrophobic integral membrane protein, presumably a cytochrome containing two b-type heme groups. The reducing equivalents are then transferred to menaquinone, which finally reduces the electron-accepting enzyme system.


Pssm-ID: 319889 [Multi-domain]  Cd Length: 138  Bit Score: 34.59  E-value: 9.81e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 2537297269  49 LKRDDEG----RERCTACGLCALACPAEAITMV 77
Cdd:cd16367    74 IHRDDGGevviSDACCGCGNCASACPYGAIQMV 106
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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