|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
54-497 |
4.76e-144 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 418.04 E-value: 4.76e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 54 QKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAH 133
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 134 LSYPAQLAFKKDLIVQALEKFQpkGFENYQINDTIGMDVPYHYRNKASLPIRKIKGEVKLGLYKRGTHDIVDLPTIATQD 213
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIG--GLPEVEVEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 214 ETSMAIVRQVGQILSDASvsfynetKNTGLVKTIIVRAnqegqaqlvlvtnveefpgrlavidaltekipalsgifqnin 293
Cdd:COG2265 159 PALNALLPALRELLAELG-------ARRGELRHLVVRA------------------------------------------ 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 294 fgktsliwgdetiklwGDDYLHEEILGLNFAFSPRAFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAF 373
Cdd:COG2265 190 ----------------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 374 LVKEVRGMEVIPEAVADARLNAEENGIENAFYEVGTAEKVFPKWAKeGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLV 453
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLW-GGRPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2527880229 454 YISCNPSTLARDLADLDSA-YQVDFIQPIDMFPQTPRWEGIVKLS 497
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
63-487 |
4.58e-134 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 394.57 E-value: 4.58e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 63 LGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAHLSYPAQLAF 142
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 143 KKDLIVQALEKFQPKGFENYQINDTIGMDvPYHYRNKASLPI-RKIKGEVKLGLYKRGTHDIVDLPTIATQDETSMAIVR 221
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPIEDVPTIGDD-PWGYRNKARLSLgRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 222 QVGQILSDASVSFYNETKNTGLVKTIIVRANQE-GQAQLVLVTNVEEFPGRLAVIDALTEKIPALSGIFQNINFGKTSLI 300
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHtGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 301 WGDETIKLWGDDYLHEEILGLNFAFSPRAFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRG 380
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 381 MEVIPEAVADARLNAEENGIENAFYEVGTAEKVFPKWAKEGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLVYISCNPS 460
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420
....*....|....*....|....*...
gi 2527880229 461 TLARDLADL-DSAYQVDFIQPIDMFPQT 487
Cdd:TIGR00479 400 TLARDLEALcKAGYTIARVQPVDMFPHT 427
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
54-487 |
1.46e-70 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 231.58 E-value: 1.46e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 54 QKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAH 133
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 134 LSYPAQLAFKKDLIVQALEKFQpkGFENYQINDTIgMDVPYHYRNKASLPIR--KIKGEVKLGLYKRGTHDIVDL---PT 208
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLA--GVEPEEVLPPI-AGPPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIdqcPV 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 209 IATQDET----------SMAIVRQVGQIlsdasvsfynetkntglvktiivranqegqaQLVLVTNveefpGRLAVI--- 275
Cdd:PRK13168 171 LVPPLSAllpplrallsSLSAKRRLGHV-------------------------------ELAQGDN-----GTALVLrhl 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 276 DALTEK-IPALsgifqnINFGKT-SLIW-----GDETIKLWGDDYL----HEEILGLNFAFSPRAFLQLNH---EQMTKT 341
Cdd:PRK13168 215 EPLSEAdRAKL------RAFAEQhGLQLylqpkGPDLVHLLGPADAqlsyYLPEFGLRLAFSPRDFIQVNAqvnQKMVAR 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 342 yeiAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRGMEVIPEAVADARLNAEENGIENA-FYEvgtA--EKVFPK-- 416
Cdd:PRK13168 289 ---ALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVtFYH---AnlEEDFTDqp 362
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2527880229 417 WAKEGFapTAVVVDPPRPGlddAFK--RALLKTKPKKLVYISCNPSTLARDLADLDSA-YQVDFIQPIDMFPQT 487
Cdd:PRK13168 363 WALGGF--DKVLLDPPRAG---AAEvmQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHT 431
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
303-499 |
1.95e-15 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 77.48 E-value: 1.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 303 DETIKLWGDDYLHEEILGlnfafsprAFLQLNHEQMTKTYEIAIKALDLNKGDtLVDAYSGVGTLGLSMAFLVKEVRGME 382
Cdd:pfam05958 160 DETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTQGSKGD-LLELYCGNGNFSLALARNFRKVLATE 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 383 VIPEAVADARLNAEENGIENA---------FYEVGTAEKVFPKWAK---EGFAPTAVVVDPPRPGLDDAFKRalLKTKPK 450
Cdd:pfam05958 231 IAKPSVAAAQYNIAANNIDNVqiirmsaeeFTQAMNGVREFNRLKGidlKSYNCSTIFVDPPRAGLDPETLK--LVQAYP 308
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2527880229 451 KLVYISCNPSTLARDLADLDSAYQVDFIQPIDMFPQTPRWEGIVKLSLK 499
Cdd:pfam05958 309 RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
356-457 |
3.01e-06 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 45.88 E-value: 3.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 356 TLVDAYSGVGTLGLSMA-FLVKEVRGMEVIPEAVADARLNAEENGIENAFYEVGTAEKvFPKWAKEGFapTAVVVDPP-- 432
Cdd:cd02440 1 RVLDLGCGTGALALALAsGPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEE-LPPEADESF--DVIISDPPlh 77
|
90 100
....*....|....*....|....*..
gi 2527880229 433 --RPGLDDAFKRALLKTKPKKLVYISC 457
Cdd:cd02440 78 hlVEDLARFLEEARRLLKPGGVLVLTL 104
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TrmA |
COG2265 |
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure ... |
54-497 |
4.76e-144 |
|
tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family [Translation, ribosomal structure and biogenesis]; tRNA/tmRNA/rRNA uracil-C5-methylase, TrmA/RlmC/RlmD family is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 441866 [Multi-domain] Cd Length: 377 Bit Score: 418.04 E-value: 4.76e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 54 QKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAH 133
Cdd:COG2265 1 EILELTIEDLAHGGDGVARHDGKVVFVPGALPGERVRVRVTKVKKSFARAKLVEVLEPSPDRVEPPCPHFGRCGGCQLQH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 134 LSYPAQLAFKKDLIVQALEKFQpkGFENYQINDTIGMDVPYHYRNKASLPIRKIKGEVKLGLYKRGTHDIVDLPTIATQD 213
Cdd:COG2265 81 LSYEAQLELKQRVVREALERIG--GLPEVEVEPIIGSPEPWGYRNRARLSVRRTDGRLRLGFYARGSHELVDIDECPLLD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 214 ETSMAIVRQVGQILSDASvsfynetKNTGLVKTIIVRAnqegqaqlvlvtnveefpgrlavidaltekipalsgifqnin 293
Cdd:COG2265 159 PALNALLPALRELLAELG-------ARRGELRHLVVRA------------------------------------------ 189
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 294 fgktsliwgdetiklwGDDYLHEEILGLNFAFSPRAFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAF 373
Cdd:COG2265 190 ----------------GRDYLTERLGGLTFRISPGSFFQVNPEQAEALYAAALEWLDLTGGERVLDLYCGVGTFALPLAR 253
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 374 LVKEVRGMEVIPEAVADARLNAEENGIENAFYEVGTAEKVFPKWAKeGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLV 453
Cdd:COG2265 254 RAKKVIGVEIVPEAVEDARENARLNGLKNVEFVAGDLEEVLPELLW-GGRPDVVVLDPPRAGAGPEVLEALAALGPRRIV 332
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2527880229 454 YISCNPSTLARDLADLDSA-YQVDFIQPIDMFPQTPRWEGIVKLS 497
Cdd:COG2265 333 YVSCNPATLARDLALLVEGgYRLEKVQPVDMFPHTHHVESVALLE 377
|
|
| rumA |
TIGR00479 |
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA ... |
63-487 |
4.58e-134 |
|
23S rRNA (uracil-5-)-methyltransferase RumA; This protein family was first proposed to be RNA methyltransferases by homology to the TrmA family. The member from E. coli has now been shown to act as the 23S RNA methyltransferase for the conserved U1939. The gene is now designated rumA and was previously designated ygcA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129571 [Multi-domain] Cd Length: 431 Bit Score: 394.57 E-value: 4.58e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 63 LGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAHLSYPAQLAF 142
Cdd:TIGR00479 1 LDHQGEGVARFNGKTVFVPGALPGEKAEVRVTEVKKQYARARVKKILEDSPERTTPPCPHFGQCGGCQLQHLSYELQLRS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 143 KKDLIVQALEKFQPKGFENYQINDTIGMDvPYHYRNKASLPI-RKIKGEVKLGLYKRGTHDIVDLPTIATQDETSMAIVR 221
Cdd:TIGR00479 81 KQQQVIALLERIGKFVSEPIEDVPTIGDD-PWGYRNKARLSLgRSPSGQLQAGFYQKGSHDIVDVKQCPVQAPALNALLP 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 222 QVGQILSDASVSFYNETKNTGLVKTIIVRANQE-GQAQLVLVTNVEEFPGRLAVIDALTEKIPALSGIFQNINFGKTSLI 300
Cdd:TIGR00479 160 KVRAILENFGASRYLEHKELGQARHGVLRIGRHtGELSSVDRTALERFPHKEELDLYLQPDSPDVKSICQNINPEKTNVI 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 301 WGDETIKLWGDDYLHEEILGLNFAFSPRAFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRG 380
Cdd:TIGR00479 240 FGEETEVIAGEMPIYDKSGDLSFTFSARDFIQVNSGQNEKLVDRALEWLELQGEERVLDAYCGMGTFTLPLAKQAKSVVG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 381 MEVIPEAVADARLNAEENGIENAFYEVGTAEKVFPKWAKEGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLVYISCNPS 460
Cdd:TIGR00479 320 VEGVPESVEKAQQNAELNGIANVTFYHGTLETVLPKQPWAGNGFDKVLLDPPRKGCAAGVLRTIIKLKPERIVYVSCNPA 399
|
410 420
....*....|....*....|....*...
gi 2527880229 461 TLARDLADL-DSAYQVDFIQPIDMFPQT 487
Cdd:TIGR00479 400 TLARDLEALcKAGYTIARVQPVDMFPHT 427
|
|
| rumA |
PRK13168 |
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD; |
54-487 |
1.46e-70 |
|
23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD;
Pssm-ID: 237291 [Multi-domain] Cd Length: 443 Bit Score: 231.58 E-value: 1.46e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 54 QKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKYIEAKVVTIREESQDRVTPEDPAADLVGGFELAH 133
Cdd:PRK13168 14 QIITVTIESLDHDGRGVARHNGKTVFIEGALPGERVEVQVTEDKKQYARAKVVRILKPSPERVTPRCPHFGVCGGCQLQH 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 134 LSYPAQLAFKKDLIVQALEKFQpkGFENYQINDTIgMDVPYHYRNKASLPIR--KIKGEVKLGLYKRGTHDIVDL---PT 208
Cdd:PRK13168 94 LSIDAQIASKQRALEDLLKHLA--GVEPEEVLPPI-AGPPWGYRRRARLSVRyvPKKGQLLVGFREKNSSDIVDIdqcPV 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 209 IATQDET----------SMAIVRQVGQIlsdasvsfynetkntglvktiivranqegqaQLVLVTNveefpGRLAVI--- 275
Cdd:PRK13168 171 LVPPLSAllpplrallsSLSAKRRLGHV-------------------------------ELAQGDN-----GTALVLrhl 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 276 DALTEK-IPALsgifqnINFGKT-SLIW-----GDETIKLWGDDYL----HEEILGLNFAFSPRAFLQLNH---EQMTKT 341
Cdd:PRK13168 215 EPLSEAdRAKL------RAFAEQhGLQLylqpkGPDLVHLLGPADAqlsyYLPEFGLRLAFSPRDFIQVNAqvnQKMVAR 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 342 yeiAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRGMEVIPEAVADARLNAEENGIENA-FYEvgtA--EKVFPK-- 416
Cdd:PRK13168 289 ---ALEWLDPQPGDRVLDLFCGLGNFTLPLARQAAEVVGVEGVEAMVERARENARRNGLDNVtFYH---AnlEEDFTDqp 362
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2527880229 417 WAKEGFapTAVVVDPPRPGlddAFK--RALLKTKPKKLVYISCNPSTLARDLADLDSA-YQVDFIQPIDMFPQT 487
Cdd:PRK13168 363 WALGGF--DKVLLDPPRAG---AAEvmQALAKLGPKRIVYVSCNPATLARDAGVLVEAgYRLKRAGMLDMFPHT 431
|
|
| rumB |
PRK03522 |
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC; |
235-499 |
2.78e-31 |
|
23S rRNA (uracil(747)-C(5))-methyltransferase RlmC;
Pssm-ID: 235128 [Multi-domain] Cd Length: 315 Bit Score: 122.67 E-value: 2.78e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 235 YNETKNTGLVKTIIVRANQ-EGQAQLVLVTNVEEFPGRL-AVIDALTEKIPALSGIFQNINFGKTSLIWGDETIKLWGDD 312
Cdd:PRK03522 53 YNVARKRGELKYILLTESQsDGELMLRFVLRSETKLARLrRALPWLQAQLPQLKVISVNIQPVHMAILEGEEEIFLTEQQ 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 313 YLHEEILGLNFAFSPRAFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRGMEVIPEAVADAR 392
Cdd:PRK03522 133 ALPERFNGVPLFIRPQSFFQTNPAVAAQLYATARDWVRELPPRSMWDLFCGVGGFGLHCATPGMQLTGIEISAEAIACAK 212
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 393 LNAEENGIENAFYEVGTAekvfPKWAK-EGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLVYISCNPSTLARDLADLdS 471
Cdd:PRK03522 213 QSAAELGLTNVQFQALDS----TQFATaQGEVPDLVLVNPPRRGIGKELCDYLSQMAPRFILYSSCNAQTMAKDLAHL-P 287
|
250 260
....*....|....*....|....*...
gi 2527880229 472 AYQVDFIQPIDMFPQTPRWEGIVKLSLK 499
Cdd:PRK03522 288 GYRIERVQLFDMFPHTAHYEVLTLLVRQ 315
|
|
| meth_trns_rumB |
TIGR02085 |
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases ... |
176-498 |
1.27e-27 |
|
23S rRNA (uracil-5-)-methyltransferase RumB; This family consists of RNA methyltransferases designated RumB, formerly YbjF. Members act on 23S rRNA U747 and the equivalent position in other proteobacterial species. This family is homologous to the other 23S rRNA methyltransferase RumA and to the tRNA methyltransferase TrmA. [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 131140 Cd Length: 374 Bit Score: 113.78 E-value: 1.27e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 176 YRNKASLpirKIKGEVK---LGLYKR-GT-HDIVDLPTIATQDETSMAIVRQvgqILSDASVSFYNETKNTGLVKTIIV- 249
Cdd:TIGR02085 55 FRNKAKM---VVSGSVErpiLGILHRdGTpLDLCDCPLYPQSFQPVFAYLKN---FIARAGLTPYNVAKKKGELKFILLt 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 250 RANQEGQAQLVLVTNVEEFPGRL-AVIDALTEKIPALSGIFQNINFGKTSLIWGDETIKLWGDDYLHEEILGLNFAFSPR 328
Cdd:TIGR02085 129 ESENSGQLMLRFVLRSETKLAQIrRALPWLIEQLPQLEVISVNIQPVHMAILEGEEEIFLTEQQALPERFNDVPLVIRPQ 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 329 AFLQLNHEQMTKTYEIAIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRGMEVIPEAVADARLNAEENGIENAFYEVG 408
Cdd:TIGR02085 209 SFFQTNPKVAAQLYATARQWVREIPVTQMWDLFCGVGGFGLHCAGPDTQLTGIEIESEAIACAQQSAQMLGLDNLSFAAL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 409 TAEKVFpkwAKEGFAPTAVVVDPPRPGLDDAFKRALLKTKPKKLVYISCNPSTLARDLADLdSAYQVDFIQPIDMFPQTP 488
Cdd:TIGR02085 289 DSAKFA---TAQMSAPELVLVNPPRRGIGKELCDYLSQMAPKFILYSSCNAQTMAKDIAEL-SGYQIERVQLFDMFPHTS 364
|
330
....*....|
gi 2527880229 489 RWEGIVKLSL 498
Cdd:TIGR02085 365 HYEVLTLLVR 374
|
|
| tRNA_U5-meth_tr |
pfam05958 |
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC: ... |
303-499 |
1.95e-15 |
|
tRNA (Uracil-5-)-methyltransferase; This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial and eukaryotic tRNAs. The methylation of U54 is catalyzed by the tRNA(m5U54)methyltransferase, which in Saccharomyces cerevisiae is encoded by the nonessential TRM2 gene. It is thought that tRNA modification enzymes might have a role in tRNA maturation not necessarily linked to their known catalytic activity.
Pssm-ID: 428692 Cd Length: 357 Bit Score: 77.48 E-value: 1.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 303 DETIKLWGDDYLHEEILGlnfafsprAFLQLNHEQMTKTYEIAIKALDLNKGDtLVDAYSGVGTLGLSMAFLVKEVRGME 382
Cdd:pfam05958 160 DETLPVAGREFIYRQVEN--------SFTQPNAAVNIKMLEWACDVTQGSKGD-LLELYCGNGNFSLALARNFRKVLATE 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 383 VIPEAVADARLNAEENGIENA---------FYEVGTAEKVFPKWAK---EGFAPTAVVVDPPRPGLDDAFKRalLKTKPK 450
Cdd:pfam05958 231 IAKPSVAAAQYNIAANNIDNVqiirmsaeeFTQAMNGVREFNRLKGidlKSYNCSTIFVDPPRAGLDPETLK--LVQAYP 308
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2527880229 451 KLVYISCNPSTLARDLADLDSAYQVDFIQPIDMFPQTPRWEGIVKLSLK 499
Cdd:pfam05958 309 RILYISCNPETLCANLEQLSKTHRVERFALFDQFPYTHHMECGVLLEKK 357
|
|
| PRK05031 |
PRK05031 |
tRNA (uracil-5-)-methyltransferase; Validated |
310-499 |
5.64e-14 |
|
tRNA (uracil-5-)-methyltransferase; Validated
Pssm-ID: 235332 Cd Length: 362 Bit Score: 73.32 E-value: 5.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 310 GDDYLHEE--ILGLNFAFS--PRAFLQLN---HEQMTktyEIAIKALDLNKGDtLVDAYSGVGTLGLSMAFLVKEVRGME 382
Cdd:PRK05031 160 DQDYVDERlpVAGREFIYRqvENSFTQPNaavNEKML---EWALDATKGSKGD-LLELYCGNGNFTLALARNFRRVLATE 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 383 VIPEAVADARLNAEENGIENA---------FYEVGTAEKVFPKWAK---EGFAPTAVVVDPPRPGLDDAfKRALLKtKPK 450
Cdd:PRK05031 236 ISKPSVAAAQYNIAANGIDNVqiirmsaeeFTQAMNGVREFNRLKGidlKSYNFSTIFVDPPRAGLDDE-TLKLVQ-AYE 313
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2527880229 451 KLVYISCNPSTLARDLADLDSAYQVD----FiqpiDMFPQTPRWEGIVKLSLK 499
Cdd:PRK05031 314 RILYISCNPETLCENLETLSQTHKVErfalF----DQFPYTHHMECGVLLEKK 362
|
|
| TRAM |
pfam01938 |
TRAM domain; This small domain has no known function. However it may perform a nucleic acid ... |
49-106 |
4.16e-12 |
|
TRAM domain; This small domain has no known function. However it may perform a nucleic acid binding role (Bateman A. unpublished observation).
Pssm-ID: 396497 [Multi-domain] Cd Length: 59 Bit Score: 61.08 E-value: 4.16e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 2527880229 49 EVKIGQKFPLTIKRLGINGEGIGYFKR-KIVFIPGALPGEVVTAKVTDFTEKYIEAKVV 106
Cdd:pfam01938 1 RRYVGQTQEVLVEGLSSNGEGIGRTDNgKVVFVPGALPGEFVEVKITKVKRNYLRGELL 59
|
|
| COG3269 |
COG3269 |
Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; |
21-106 |
6.81e-11 |
|
Predicted RNA-binding protein, contains TRAM domain [General function prediction only];
Pssm-ID: 442500 [Multi-domain] Cd Length: 129 Bit Score: 59.68 E-value: 6.81e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 21 RGQNQSNRPRPNRYSKNQGNRSNRSQPVEVkiGQKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVTDFTEKY 100
Cdd:COG3269 43 RGAAASRRESSKRRSVGKPEAQELTPPVEE--GEEYEVEIEDIGKKGDGIARVEGFVIFVPGAEVGDRVKVKITKVKRNF 120
|
....*.
gi 2527880229 101 IEAKVV 106
Cdd:COG3269 121 AFAEVV 126
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
356-457 |
3.01e-06 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 45.88 E-value: 3.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 356 TLVDAYSGVGTLGLSMA-FLVKEVRGMEVIPEAVADARLNAEENGIENAFYEVGTAEKvFPKWAKEGFapTAVVVDPP-- 432
Cdd:cd02440 1 RVLDLGCGTGALALALAsGPGARVTGVDISPVALELARKAAAALLADNVEVLKGDAEE-LPPEADESF--DVIISDPPlh 77
|
90 100
....*....|....*....|....*..
gi 2527880229 433 --RPGLDDAFKRALLKTKPKKLVYISC 457
Cdd:cd02440 78 hlVEDLARFLEEARRLLKPGGVLVLTL 104
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
351-422 |
3.07e-04 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 41.25 E-value: 3.07e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527880229 351 LNKGDTLVDAYSGVGTLGLSMAFLV---KEVRGMEVIPEAVADARLNAEENGIENAFYEVGTAEKVFPKWAKEGF 422
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELgpnAEVVGIDISEEAIEKARENAQKLGFDNVEFEQGDIEELPELLEDDKF 75
|
|
| PRK12336 |
PRK12336 |
translation initiation factor IF-2 subunit beta; Provisional |
28-94 |
4.24e-04 |
|
translation initiation factor IF-2 subunit beta; Provisional
Pssm-ID: 183451 [Multi-domain] Cd Length: 201 Bit Score: 41.47 E-value: 4.24e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2527880229 28 RPRPNRYSKNQGNRSNrsqpveVKIGQKFPLTIKRLGINGEGIGYFKRKIVFIPGALPGEVVTAKVT 94
Cdd:PRK12336 129 RPVKKRKASSETQREA------IEEGKTYEVEITGTGRKGDGVAKKGKYTIFVPGAKKGEVVKVKIK 189
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
346-432 |
1.51e-03 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 39.79 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527880229 346 IKALDLNKGDTLVDAYSGVGTLGLSMAFL--VKEVRGMEVIPEAVADARLNAEENGIENAfyEVGTAEkVFPKWAKEGFA 423
Cdd:COG2813 42 LEHLPEPLGGRVLDLGCGYGVIGLALAKRnpEARVTLVDVNARAVELARANAAANGLENV--EVLWSD-GLSGVPDGSFD 118
|
....*....
gi 2527880229 424 ptAVVVDPP 432
Cdd:COG2813 119 --LILSNPP 125
|
|
| PRK14968 |
PRK14968 |
putative methyltransferase; Provisional |
339-407 |
3.08e-03 |
|
putative methyltransferase; Provisional
Pssm-ID: 237872 [Multi-domain] Cd Length: 188 Bit Score: 38.73 E-value: 3.08e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527880229 339 TKTYEIA------IKALDLNKGDTLVDAYSGVGTLGLSMAFLVKEVRGMEVIPEAVADARLNAEENGIENAFYEV 407
Cdd:PRK14968 3 DEVYEPAedsfllAENAVDKKGDRVLEVGTGSGIVAIVAAKNGKKVVGVDINPYAVECAKCNAKLNNIRNNGVEV 77
|
|
| cbiT |
PRK00377 |
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional |
338-402 |
8.58e-03 |
|
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
Pssm-ID: 234740 Cd Length: 198 Bit Score: 37.47 E-value: 8.58e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2527880229 338 MTKTyEI---AIKALDLNKGDTLVDAYSGVGTLGLSMAFLVKE---VRGMEVIPEAVADARLNAEENGIEN 402
Cdd:PRK00377 23 MTKE-EIralALSKLRLRKGDMILDIGCGTGSVTVEASLLVGEtgkVYAVDKDEKAINLTRRNAEKFGVLN 92
|
|
| |
