|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
27-700 |
6.16e-175 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 515.86 E-value: 6.16e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 27 LAYLIASAAGYTALAMADWVTNSRSRRGSELAKLIGAVALGGGIWSMHFLAMLSFKIGIHVHYAPLQTLASLLIAIAVSY 106
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 107 TVMHLIGRESLTAPQYGLAALAAGLGIATMHYTGMLAMQSVAVQLYDPLLVVVSVVVASLASLGALLLAFRLRGRTGLRT 186
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 187 FWLRLLGSLVLGFAIVSMHFTGMAALTLAVPIGFEPGGLAEANQHLELGMGIALGTLFIIMVGLLAAWAGERFNAQRLRL 266
Cdd:COG5001 161 LLALLLLLLLALLLLLLLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 267 ERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVL 345
Cdd:COG5001 241 KRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARArRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVARRLRACL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 346 DDDLPLARYAGDEFSLLLP-LGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGH 424
Cdd:COG5001 321 REGDTVARLGGDEFAVLLPdLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMYR 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 425 CKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVA 503
Cdd:COG5001 401 AKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLAtGRIVGAEALLRWQHPERGLVSPAEFIPLA 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 504 EETGLIADLDGWVMRQACADLAQLHREGHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLN 583
Cdd:COG5001 481 EETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDPE 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 584 VAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVET 663
Cdd:COG5001 561 EALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVET 640
|
650 660 670
....*....|....*....|....*....|....*..
gi 2527447185 664 SEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQQPA 700
Cdd:COG5001 641 EEQLEFLRELGCDYAQGYLFSRPLPAEELEALLRARA 677
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
257-698 |
2.23e-102 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 327.41 E-value: 2.23e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 257 ERfNAQRlRLERVSTTldqitlhDPLTHLLNGGSFIQTVDRAIgQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQ 336
Cdd:PRK10060 226 ER-RAQE-RLRILANT-------DSITGLPNRNAIQELIDHAI-NAADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQD 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 337 MAQRIRAVLDDDLPLARYAGDEFSLLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLR 416
Cdd:PRK10060 296 VSLAILSCLEEDQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIR 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 417 SAGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPAGAPVALEALVRWQHPVLGPLSP 496
Cdd:PRK10060 376 SADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPERGLIPP 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 497 ERFVRVAEETGLIADLDGWVMRQACADLAQLHREGhAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTEN 576
Cdd:PRK10060 456 LEFISYAEESGLIVPLGRWVMLDVVRQVAKWRDKG-INLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTES 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 577 ALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNV 656
Cdd:PRK10060 535 CLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQV 614
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 2527447185 657 VAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQQ 698
Cdd:PRK10060 615 IAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYKR 656
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
452-691 |
4.16e-97 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 299.46 E-value: 4.16e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 452 MDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQlHRE 530
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRtGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLAR-WQA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 531 GHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSS 610
Cdd:cd01948 80 GGPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 611 LAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLP 690
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 2527447185 691 Q 691
Cdd:cd01948 240 E 240
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
451-689 |
2.00e-85 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 269.09 E-value: 2.00e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 451 EMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQLHR 529
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRtGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 530 EGHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYS 609
Cdd:smart00052 81 QGPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 610 SLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPL 689
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
453-686 |
1.90e-69 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 226.82 E-value: 1.90e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 453 DLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQlhREG 531
Cdd:pfam00563 3 ALRRALENGEFVLYYQPIVDLRtGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQ--LQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 532 HAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSL 611
Cdd:pfam00563 81 GPDIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527447185 612 AYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRP 686
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
277-433 |
7.47e-33 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 124.37 E-value: 7.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 277 TLHDPLTHLLNGGSFIQTVDRAIGQART-GEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRA-VLDDDLPlARY 354
Cdd:TIGR00254 2 AVRDPLTGLYNRRYLEEMLDSELKRARRfQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSsVRGSDVV-GRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 355 AGDEFSLLLPLGQRGDSQPLAMRLLEQLRP-PFELAG-QRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNR 432
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGsETLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 2527447185 433 S 433
Cdd:TIGR00254 161 V 161
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
20-276 |
8.70e-28 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 118.51 E-value: 8.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 20 YESLLVVLAYLIASAAGYTALAMADWVT---NSRSRRGSELAkliGAVALGGGIWSMHFLAMLSFKIGIHVHYAPLQTLA 96
Cdd:NF038348 5 YDLSLVLLSLVIATLASYTALDLSALISlldKPRLRRAWLAG---GAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 97 SLLIAIAVSYTVMHLIGRESLTAPQYGLAALAAGLGIATMHYTGMLAMQSVAVQLYDPLLVVVSVVVASLASLGALLLAF 176
Cdd:NF038348 82 SLAIAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAH 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 177 RLRGRTGLRTFWLRLLGSLVLGFAIVSMHFTGMAALTlavpigFEPGGLAEANQHLE---LGMGIALGTLFIIMVGLLAA 253
Cdd:NF038348 162 RLRTENAGRVIVKRIGAATVMGVAITGMHYTGMAAAH------FAPNARCGAANGISgpwLGTTIALFTATILIVTLVIS 235
|
250 260
....*....|....*....|...
gi 2527447185 254 wageRFNAQRLRLERVSTTLDQI 276
Cdd:NF038348 236 ----RFDARTMFLRGITDALEDL 254
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| COG5001 |
COG5001 |
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain ... |
27-700 |
6.16e-175 |
|
Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms];
Pssm-ID: 444025 [Multi-domain] Cd Length: 678 Bit Score: 515.86 E-value: 6.16e-175
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 27 LAYLIASAAGYTALAMADWVTNSRSRRGSELAKLIGAVALGGGIWSMHFLAMLSFKIGIHVHYAPLQTLASLLIAIAVSY 106
Cdd:COG5001 1 LLALAALLLLLLALLLALLLLALLLLALLLAALLALALLLLLLLLLLALLLAALLLLALLALLALLLLAAALLALALAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 107 TVMHLIGRESLTAPQYGLAALAAGLGIATMHYTGMLAMQSVAVQLYDPLLVVVSVVVASLASLGALLLAFRLRGRTGLRT 186
Cdd:COG5001 81 LLAALLAALLLLLLLLLALLVLLLLLLLLLALLALLAALLARALAALLLAAASAALLAAALGAALLAALALALLLALARA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 187 FWLRLLGSLVLGFAIVSMHFTGMAALTLAVPIGFEPGGLAEANQHLELGMGIALGTLFIIMVGLLAAWAGERFNAQRLRL 266
Cdd:COG5001 161 LLALLLLLLLALLLLLLLLLLLALLLLLLLALLLRLLLLLRGGRLLRLALRLLLGLLLLGLLLLLLLVAVLAIARLITER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 267 ERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVL 345
Cdd:COG5001 241 KRAEERLRHLAYHDPLTGLPNRRLFLDRLEQALARArRSGRRLALLFIDLDRFKEINDTLGHAAGDELLREVARRLRACL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 346 DDDLPLARYAGDEFSLLLP-LGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGH 424
Cdd:COG5001 321 REGDTVARLGGDEFAVLLPdLDDPEDAEAVAERILAALAEPFELDGHELYVSASIGIALYPDDGADAEELLRNADLAMYR 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 425 CKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVA 503
Cdd:COG5001 401 AKAAGRNRYRFFDPEMDERARERLELEADLRRALERGELELHYQPQVDLAtGRIVGAEALLRWQHPERGLVSPAEFIPLA 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 504 EETGLIADLDGWVMRQACADLAQLHREGHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLN 583
Cdd:COG5001 481 EETGLIVPLGEWVLREACRQLAAWQDAGLPDLRVAVNLSARQLRDPDLVDRVRRALAETGLPPSRLELEITESALLEDPE 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 584 VAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVET 663
Cdd:COG5001 561 EALETLRALRALGVRIALDDFGTGYSSLSYLKRLPVDTLKIDRSFVRDLAEDPDDAAIVRAIIALAHSLGLEVVAEGVET 640
|
650 660 670
....*....|....*....|....*....|....*..
gi 2527447185 664 SEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQQPA 700
Cdd:COG5001 641 EEQLEFLRELGCDYAQGYLFSRPLPAEELEALLRARA 677
|
|
| PRK10060 |
PRK10060 |
cyclic di-GMP phosphodiesterase; |
257-698 |
2.23e-102 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 236645 [Multi-domain] Cd Length: 663 Bit Score: 327.41 E-value: 2.23e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 257 ERfNAQRlRLERVSTTldqitlhDPLTHLLNGGSFIQTVDRAIgQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQ 336
Cdd:PRK10060 226 ER-RAQE-RLRILANT-------DSITGLPNRNAIQELIDHAI-NAADNNQVGIVYLDLDNFKKVNDAYGHMFGDQLLQD 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 337 MAQRIRAVLDDDLPLARYAGDEFSLLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLR 416
Cdd:PRK10060 296 VSLAILSCLEEDQTLARLGGDEFLVLASHTSQAALEAMASRILTRLRLPFRIGLIEVYTGCSIGIALAPEHGDDSESLIR 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 417 SAGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPAGAPVALEALVRWQHPVLGPLSP 496
Cdd:PRK10060 376 SADTAMYTAKEGGRGQFCVFSPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPERGLIPP 455
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 497 ERFVRVAEETGLIADLDGWVMRQACADLAQLHREGhAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTEN 576
Cdd:PRK10060 456 LEFISYAEESGLIVPLGRWVMLDVVRQVAKWRDKG-INLRVAVNVSARQLADQTIFTALKQALQELNFEYCPIDVELTES 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 577 ALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNV 656
Cdd:PRK10060 535 CLIENEELALSVIQQFSQLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQSFVRDIHKQPVSQSLVRAIVAVAQALNLQV 614
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 2527447185 657 VAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQQ 698
Cdd:PRK10060 615 IAEGVETAKEDAFLTKNGVNERQGFLFAKPMPAVAFERWYKR 656
|
|
| EAL |
COG2200 |
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) ... |
182-697 |
1.93e-98 |
|
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant) [Signal transduction mechanisms];
Pssm-ID: 441802 [Multi-domain] Cd Length: 576 Bit Score: 314.80 E-value: 1.93e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 182 TGLRTFWLRLLGSLVLGFAIVSMHFTGMAALTLAVPIGFEPGGLAEANQHLELGMGIALGTLFIIMVGLLAAWAGERFNA 261
Cdd:COG2200 59 LLALALLLLLLLLLLLLLLLLLLLLALLLLLLLLLLLLLLLLLLLALLLAALLALLLLLLLLLLLLLLSLLLLLVLVLLR 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 262 QRLRLERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRI 341
Cdd:COG2200 139 LALELLLALLLLALLALLDLLLLLLLRRLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLDNDGLGGAGLLLLLLLALL 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 342 RAVLDDDLPLARYAGDEFS---LLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSA 418
Cdd:COG2200 219 LLLLLARLLLALLGGGGGGfllLLLLLAAAAAAAAALRLLLLLLLEPLLLGGGLVVVASSGGGAAAPDDGADAALLLAAA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 419 GLAVGHCKRSGRNRSQRFTTELQRDADDLlSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPE 497
Cdd:COG2200 299 AAAAAAAAGGGRGRVVFFAAAEARARRRL-ALESELREALEEGELRLYYQPIVDLRtGRVVGYEALLRWRHPDGGLISPA 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 498 RFVRVAEETGLIADLDGWVMRQACADLAQLHREGHAaMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENA 577
Cdd:COG2200 378 EFIPAAERSGLIVELDRWVLERALRQLARWPERGLD-LRLSVNLSARSLLDPDFLERLLELLAEYGLPPERLVLEITESA 456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 578 LMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVV 657
Cdd:COG2200 457 LLEDLEAAIELLARLRALGVRIALDDFGTGYSSLSYLKRLPPDYLKIDRSFVRDIARDPRDQAIVRAIVALAHRLGLKVV 536
|
490 500 510 520
....*....|....*....|....*....|....*....|
gi 2527447185 658 AEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQ 697
Cdd:COG2200 537 AEGVETEEQLEALRELGCDYAQGYLFGRPLPLEELEALLR 576
|
|
| EAL |
cd01948 |
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
452-691 |
4.16e-97 |
|
EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.
Pssm-ID: 238923 [Multi-domain] Cd Length: 240 Bit Score: 299.46 E-value: 4.16e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 452 MDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQlHRE 530
Cdd:cd01948 1 ADLRRALERGEFELYYQPIVDLRtGRIVGYEALLRWRHPEGGLISPAEFIPLAEETGLIVELGRWVLEEACRQLAR-WQA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 531 GHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSS 610
Cdd:cd01948 80 GGPDLRLSVNLSARQLRDPDFLDRLLELLAETGLPPRRLVLEITESALIDDLEEALATLRRLRALGVRIALDDFGTGYSS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 611 LAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLP 690
Cdd:cd01948 160 LSYLKRLPVDYLKIDRSFVRDIETDPEDRAIVRAIIALAHSLGLKVVAEGVETEEQLELLRELGCDYVQGYLFSRPLPAE 239
|
.
gi 2527447185 691 Q 691
Cdd:cd01948 240 E 240
|
|
| PRK11359 |
PRK11359 |
cyclic-di-GMP phosphodiesterase; Provisional |
251-697 |
9.07e-92 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183097 [Multi-domain] Cd Length: 799 Bit Score: 303.23 E-value: 9.07e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 251 LAAWAGERfnaqrlrlERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQARtgeQFALLMLDIDHFKRINDSLGHALG 330
Cdd:PRK11359 358 LAALALEQ--------EKSRQHIEQLIQFDPLTGLPNRNNLHNYLDDLVDKAV---SPVVYLIGVDHFQDVIDSLGYAWA 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 331 DELLIQMAQRIRAVLDDDLPLARYAGDEFSLLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHypQDGAN 410
Cdd:PRK11359 427 DQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISY--DVGKN 504
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 411 AGQLLRSAGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHP 489
Cdd:PRK11359 505 RDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIFAEtGELYGIEALARWHDP 584
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 490 VLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQLHREGHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASAL 569
Cdd:PRK11359 585 LHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQL 664
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 570 ILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMA 649
Cdd:PRK11359 665 TVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAITSIG 744
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 2527447185 650 HKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQLRTWLQ 697
Cdd:PRK11359 745 QSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMS 792
|
|
| EAL |
smart00052 |
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a ... |
451-689 |
2.00e-85 |
|
Putative diguanylate phosphodiesterase; Putative diguanylate phosphodiesterase, present in a variety of bacteria.
Pssm-ID: 214491 [Multi-domain] Cd Length: 242 Bit Score: 269.09 E-value: 2.00e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 451 EMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQLHR 529
Cdd:smart00052 1 ERELRQALENGQFLLYYQPIVSLRtGRLVGVEALIRWQHPEGGIISPDEFIPLAEETGLIVPLGRWVLEQACQQLAEWQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 530 EGHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYS 609
Cdd:smart00052 81 QGPPPLLISINLSARQLISPDLVPRVLELLEETGLPPQRLELEITESVLLDDDESAVATLQRLRELGVRIALDDFGTGYS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 610 SLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPL 689
Cdd:smart00052 161 SLSYLKRLPVDLLKIDKSFVRDLQTDPEDEAIVQSIIELAQKLGLQVVAEGVETPEQLDLLRSLGCDYGQGYLFSRPLPL 240
|
|
| EAL |
pfam00563 |
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL ... |
453-686 |
1.90e-69 |
|
EAL domain; This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues. The EAL domain is a good candidate for a diguanylate phosphodiesterase function. The domain contains many conserved acidic residues that could participate in metal binding and might form the phosphodiesterase active site.
Pssm-ID: 425752 [Multi-domain] Cd Length: 235 Bit Score: 226.82 E-value: 1.90e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 453 DLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQlhREG 531
Cdd:pfam00563 3 ALRRALENGEFVLYYQPIVDLRtGRVVGYEALLRWQHPDGGLISPARFLPLAEELGLIAELDRWVLEQALADLAQ--LQL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 532 HAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSL 611
Cdd:pfam00563 81 GPDIKLSINLSPASLADPGFLELLRALLKQAGPPPSRLVLEITESDLLARLEALREVLKRLRALGIRIALDDFGTGYSSL 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2527447185 612 AYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRP 686
Cdd:pfam00563 161 SYLLRLPPDFVKIDRSLIADIDKDGEARAIVRALIALAHSLGIKVVAEGVETEEQLEALRELGCDLVQGYYFSKP 235
|
|
| YjcC |
COG4943 |
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal ... |
447-706 |
2.53e-68 |
|
Redox-sensing c-di-GMP phosphodiesterase, contains CSS-motif and EAL domains [Signal transduction mechanisms];
Pssm-ID: 443970 [Multi-domain] Cd Length: 528 Bit Score: 233.27 E-value: 2.53e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 447 LLSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLA 525
Cdd:COG4943 269 RLSPRRRLRRAIKRREFYVHYQPIVDLKtGRCVGAEALVRWRDPDGSVISPDIFIPLAEQSGLISPLTRQVIEQVFRDLG 348
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 526 QLHREgHAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTENALMhSLNVAVEVLGEIRTLGVRVSIDDFG 605
Cdd:COG4943 349 DLLAA-DPDFHISINLSASDLLSPRFLDDLERLLARTGVAPQQIVLEITERGFI-DPAKARAVIAALREAGHRIAIDDFG 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 606 SGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGR 685
Cdd:COG4943 427 TGYSSLSYLQTLPVDILKIDKSFVDAIGTDSANSAVVPHIIEMAKTLNLDVVAEGVETEEQADYLRARGVQYGQGWLFAK 506
|
250 260
....*....|....*....|.
gi 2527447185 686 PMPLPQLRTWLQQPALAAVPA 706
Cdd:COG4943 507 PLPAEEFIAWLAAQRAPASAP 527
|
|
| PRK13561 |
PRK13561 |
putative diguanylate cyclase; Provisional |
259-699 |
3.05e-67 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 184143 [Multi-domain] Cd Length: 651 Bit Score: 233.45 E-value: 3.05e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 259 FNAQRLRLERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQARTgeqFALLMLDIDHFKRINDSLGHALGDELLIQMA 338
Cdd:PRK13561 213 YNLNQQLLQRQYEEQSRNATRFPVSDLPNKALLMALLEQVVARKQT---TALMIITCETLRDTAGVLKEAQREILLLTLV 289
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 339 QRIRAVLDDDLPLARYAGDEFSLLLplgqRGDSQP-----LAMRLLEQLRPPFELAGQRIAMTFSLGIAHYpQDGANAGQ 413
Cdd:PRK13561 290 EKLKSVLSPRMVLAQISGYDFAIIA----NGVKEPwhaitLGQQVLTIINERLPIQRIQLRPSCSIGIAMF-YGDLTAEQ 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 414 LLRSAGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLG 492
Cdd:PRK13561 365 LYSRAISAAFTARRKGKNQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMRsGKLVSAEALLRMQQPDGS 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 493 PLSPERFVRVAEETGLIADLDGWVMRQACADLAQLHREGhAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILE 572
Cdd:PRK13561 445 WDLPEGLIDRIESCGLMVTVGHWVLEESCRLLAAWQERG-IMLPLSVNLSALQLMHPNMVADMLELLTRYRIQPGTLILE 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 573 VTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSR---LPVDSLKVDRAFVRTIPkqsNDMAIAAAIIAMA 649
Cdd:PRK13561 524 VTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAGLRQLQHmksLPIDVLKIDKMFVDGLP---EDDSMVAAIIMLA 600
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|.
gi 2527447185 650 HKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQL-RTWLQQP 699
Cdd:PRK13561 601 QSLNLQVIAEGVETEAQRDWLLKAGVGIAQGFLFARALPIEIFeERYLEEK 651
|
|
| PRK11829 |
PRK11829 |
biofilm formation regulator HmsP; Provisional |
259-688 |
3.58e-64 |
|
biofilm formation regulator HmsP; Provisional
Pssm-ID: 183329 [Multi-domain] Cd Length: 660 Bit Score: 225.21 E-value: 3.58e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 259 FNAQRLRLERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMA 338
Cdd:PRK11829 214 YNRNQQLLADAYADMGRISHRFPVTELPNRSLFISLLEKEIASSTRTDHFHLLVIGIETLQEVSGAMSEAQHQQLLLTIV 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 339 QRIRAVLDDDLPLARYAGDEFSLLLPLGQR-GDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRS 417
Cdd:PRK11829 294 QRIEQCIDDSDLLAQLSKTEFAVLARGTRRsFPAMQLARRIMSQVTQPLFFDEITLRPSASIGITRYQAQQDTAESMMRN 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 418 AGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQGGLHVAYQPIVDPAGAPVA-LEALVRWQHPVLGPLSP 496
Cdd:PRK11829 374 ASTAMMAAHHEGRNQIMVFEPHLIEKTHKRLTQENDLLQAIENHDFTLFLQPQWDMKRQQVIgAEALLRWCQPDGSYVLP 453
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 497 ERFVRVAEETGLIADLDGWVMRQACADLAQLHREGhAAMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALILEVTEN 576
Cdd:PRK11829 454 SGFVHFAEEEGMMVPLGNWVLEEACRILADWKARG-VSLPLSVNISGLQVQNKQFLPHLKTLISHYHIDPQQLLLEITET 532
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 577 ALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYL---SRLPVDSLKVDRAFVRTIPKqsnDMAIAAAIIAMAHKLG 653
Cdd:PRK11829 533 AQIQDLDEALRLLRELQGLGLLIALDDFGIGYSSLRYLnhlKSLPIHMIKLDKSFVKNLPE---DDAIARIISCVSDVLK 609
|
410 420 430
....*....|....*....|....*....|....*
gi 2527447185 654 LNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMP 688
Cdd:PRK11829 610 VRVMAEGVETEEQRQWLLEHGIQCGQGFLFSPPLP 644
|
|
| PRK09776 |
PRK09776 |
putative diguanylate cyclase; Provisional |
278-689 |
2.85e-53 |
|
putative diguanylate cyclase; Provisional
Pssm-ID: 182070 [Multi-domain] Cd Length: 1092 Bit Score: 198.74 E-value: 2.85e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 278 LHDPLTHLLNGGSFIQTVDRAIGQAR-TGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVLDDDLPLARYAG 356
Cdd:PRK09776 666 SHDALTHLANRASFEKQLRRLLQTVNsTHQRHALVFIDLDRFKAVNDSAGHAAGDALLRELASLMLSMLRSSDVLARLGG 745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 357 DEFSLLLPLGQRGDSQPLAMRLLEQLRP-PFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNRsqr 435
Cdd:PRK09776 746 DEFGLLLPDCNVESARFIATRIISAINDyHFPWEGRVYRVGASAGITLIDANNHQASEVMSQADIACYAAKNAGRGR--- 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 436 fTTELQRDADDLLSLEMDLRQAlaqgglhvayqpivdpAGAPVALEA-LVRWQHPVLGPLSPER---------------- 498
Cdd:PRK09776 823 -VTVYEPQQAAAHSEHRALSLA----------------EQWRMIKENqLMMLAHGVASPRIPEArnhwlislrlwdpege 885
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 499 ------FVRVAEETGLIADLDGWVMRQACADLAQ-LHREGhaaMRVSVNCSALNLSDRLLPQSIARALQAEDLPASALIL 571
Cdd:PRK09776 886 iidegaFRPAAEDPALMHALDRRVIHEFFRQAAKaVASKG---LSIALPLSVAGLSSPTLLPFLLEQLENSPLPPRLLHL 962
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 572 EVTENALMHSLNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHK 651
Cdd:PRK09776 963 EITETALLNHAESASRLVQKLRLAGCRVVLSDFGRGLSSFNYLKAFMADYLKLDGELVANLHGNLMDEMLISIIQGHAQR 1042
|
410 420 430
....*....|....*....|....*....|....*...
gi 2527447185 652 LGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPL 689
Cdd:PRK09776 1043 LGMKTIAGPVELPLVLDTLSGIGVDLAYGYAIARPQPL 1080
|
|
| GGDEF |
cd01949 |
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: ... |
278-434 |
3.08e-48 |
|
Diguanylate-cyclase (DGC) or GGDEF domain; Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.
Pssm-ID: 143635 [Multi-domain] Cd Length: 158 Bit Score: 166.96 E-value: 3.08e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 278 LHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVLDDDLPLARYAG 356
Cdd:cd01949 1 YTDPLTGLPNRRAFEERLERLLARArRSGRPLALLLIDIDHFKQINDTYGHAAGDEVLKEVAERLRSSLRESDLVARLGG 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2527447185 357 DEFSLLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNRSQ 434
Cdd:cd01949 81 DEFAILLPGTDLEEAEALAERLREAIEEPFFIDGQEIRVTASIGIATYPEDGEDAEELLRRADEALYRAKRSGRNRVV 158
|
|
| MHYT |
COG3300 |
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms]; |
19-461 |
3.31e-47 |
|
MHYT domain, NO-binding membrane sensor [Signal transduction mechanisms];
Pssm-ID: 442529 [Multi-domain] Cd Length: 440 Bit Score: 173.22 E-value: 3.31e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 19 EYESLLVVLAYLIASAAGYTALAMADWVTNSRSRRgSELAKLIGAVALGGGIWSMHFLAMLSFKIGIHVHYAPLQTLASL 98
Cdd:COG3300 6 SHDPWLVALSVLIAVLGSYTALDLARRARAASGRA-RRAWLALAALALGGGIWSMHFIAMLAFRLPVPVGYDPPLTLLSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 99 LIAIAVSYTVMHLIGRESLTAPQYGLAALAAGLGIATMHYTGMLAMQSVAVQLYDPLLVVVSVVVASLASLGALLLAFRL 178
Cdd:COG3300 85 LVAILASGLALALASRRRLSRLRLLLGGLLMGLGIAAMHYTGMAAMRMAGAISYDPALVALSVLIAVVASTAALWLAFRL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 179 RGRtglrtfWLRLLGSLVLGFAIVSMHFTGMAALTLAVPIGFEPGGLAEANQHleLGMGIALGTLFIIMVGLLAA--WAG 256
Cdd:COG3300 165 RSL------RRRLGAALVMGLAICGMHYTGMAAATFVPDPGAPAPAPGLSPTL--LALAVAVVTLLILGLALLASllDDA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 257 ERFNAQRLRLERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIG-QARTGEQFALLMLDIDHFKRINDSLGHALGDELLI 335
Cdd:COG3300 237 RRRARAARELASLRLLAALALAGLLLTGLLLALEARGALAALLGaALDELLLDLLLLLDLDGDAALLLALGELLADLLLA 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 336 QMAQRIRAVLDDDLPLARYAGDEFslLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLL 415
Cdd:COG3300 317 LVAARVVARVRLVARVGGDERDEI--VAEDRLRRAEAEAAADAARLALAAAASALSLDALLLLALLAAAALALALAALLA 394
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 2527447185 416 RSAGLAVGHCKRSGRNRSQRFTTELQRDADDLLSLEMDLRQALAQG 461
Cdd:COG3300 395 LRALAAADALTVEADASSAAAELLLAAALLLLLLLLLLLLLLLARD 440
|
|
| GGDEF |
COG2199 |
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants ... |
176-432 |
1.47e-45 |
|
GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms];
Pssm-ID: 441801 [Multi-domain] Cd Length: 275 Bit Score: 163.61 E-value: 1.47e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 176 FRLRGRTGLRTFWLRLLGSLVLGFAIVSMHFTGMAALTLAVPIGFEPGGLAEANQHLELGMGIALGTLFIIMVGLLAAWA 255
Cdd:COG2199 17 LLLLSLLLALLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLVLLLLALGLLLLALLLLSLVLELLLLLLALLLLLLA 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 256 GERFNAQRLRLERvsttLDQITLHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELL 334
Cdd:COG2199 97 LEDITELRRLEER----LRRLATHDPLTGLPNRRAFEERLERELARArREGRPLALLLIDLDHFKRINDTYGHAAGDEVL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 335 IQMAQRIRAVLDDDLPLARYAGDEFSLLLPlgqrGDSQPLAMRLLEQLR-----PPFELAGQRIAMTFSLGIAHYPQDGA 409
Cdd:COG2199 173 KEVARRLRASLRESDLVARLGGDEFAVLLP----GTDLEEAEALAERLRealeqLPFELEGKELRVTVSIGVALYPEDGD 248
|
250 260
....*....|....*....|...
gi 2527447185 410 NAGQLLRSAGLAVGHCKRSGRNR 432
Cdd:COG2199 249 SAEELLRRADLALYRAKRAGRNR 271
|
|
| PRK10551 |
PRK10551 |
cyclic di-GMP phosphodiesterase; |
456-699 |
9.70e-44 |
|
cyclic di-GMP phosphodiesterase;
Pssm-ID: 182541 [Multi-domain] Cd Length: 518 Bit Score: 165.16 E-value: 9.70e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 456 QALAQGGLHVAYQPIVDPA-GAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQLHREGHAA 534
Cdd:PRK10551 270 TGIKRGQFYVEYQPVVDTQtLRVTGLEALLRWRHPTAGEIPPDAFINYAEAQKLIVPLTQHLFELIARDAAELQKVLPVG 349
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 535 MRVSVNCSALNLSDRLLPQSIARALQAedLPAS--ALILEVTENALMHSLNvAVEVLGEIRTLGVRVSIDDFGSGYSSLA 612
Cdd:PRK10551 350 AKLGINISPAHLHSDSFKADVQRLLAS--LPADhfQIVLEITERDMVQEEE-ATKLFAWLHSQGIEIAIDDFGTGHSALI 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 613 YLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQL 692
Cdd:PRK10551 427 YLERFTLDYLKIDRGFIQAIGTETVTSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLRERGVNFLQGYWISRPLPLEDF 506
|
....*..
gi 2527447185 693 RTWLQQP 699
Cdd:PRK10551 507 VRWLKEP 513
|
|
| GGDEF |
pfam00990 |
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of ... |
277-432 |
2.66e-42 |
|
Diguanylate cyclase, GGDEF domain; This domain is found linked to a wide range of non-homologous domains in a variety of bacteria. It has been shown to be homologous to the adenylyl cyclase catalytic domain and has diguanylate cyclase activity. This observation correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. In the WspR protein of Pseudomonas aeruginosa, the GGDEF domain acts as a diguanylate cyclase, PDB:3bre, when the whole molecule appears to form a tetramer consisting of two symmetrically-related dimers representing a biological unit. The active site is the GGD/EF motif, buried in the structure, and the cyclic dimeric guanosine monophosphate (c-di-GMP) bind to the inhibitory-motif RxxD on the surface. The enzyme thus catalyzes the cyclization of two guanosine triphosphate (GTP) molecules to one c-di-GMP molecule.
Pssm-ID: 425976 [Multi-domain] Cd Length: 160 Bit Score: 150.48 E-value: 2.66e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 277 TLHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVL-DDDLpLARY 354
Cdd:pfam00990 1 AAHDPLTGLPNRRYFEEQLEQELQRAlREGSPVAVLLIDLDNFKRINDTYGHSVGDEVLQEVAQRLSSSLrRSDL-VARL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 355 AGDEFSLLLP---LGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRN 431
Cdd:pfam00990 80 GGDEFAILLPetsLEGAQELAERIRRLLAKLKIPHTVSGLPLYVTISIGIAAYPNDGEDPEDLLKRADTALYQAKQAGRN 159
|
.
gi 2527447185 432 R 432
Cdd:pfam00990 160 R 160
|
|
| GGDEF |
smart00267 |
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria. |
275-434 |
8.42e-38 |
|
diguanylate cyclase; Diguanylate cyclase, present in a variety of bacteria.
Pssm-ID: 128563 [Multi-domain] Cd Length: 163 Bit Score: 138.15 E-value: 8.42e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 275 QITLHDPLTHLLNGGSFIQTVDRAIGQA-RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVL-DDDLpLA 352
Cdd:smart00267 1 RLAFRDPLTGLPNRRYFEEELEQELQRAqRQGSPFALLLIDLDNFKDINDTYGHAVGDELLQEVAQRLSSCLrPGDL-LA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 353 RYAGDEFSLLLPLGQRGDSQPLAMRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNR 432
Cdd:smart00267 80 RLGGDEFALLLPETSLEEAIALAERILQQLREPIIIHGIPLYLTISIGVAAYPNPGEDAEDLLKRADTALYQAKKAGRNQ 159
|
..
gi 2527447185 433 SQ 434
Cdd:smart00267 160 VA 161
|
|
| GGDEF |
TIGR00254 |
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by ... |
277-433 |
7.47e-33 |
|
diguanylate cyclase (GGDEF) domain; The GGDEF domain is named for the motif GG[DE]EF shared by many proteins carrying the domain. There is evidence that the domain has diguanylate cyclase activity. Several proteins carrying this domain also carry domains with functions relating to environmental sensing. These include PleD, a response regulator protein involved in the swarmer-to-stalked cell transition in Caulobacter crescentus, and FixL, a heme-containing oxygen sensor protein. [Regulatory functions, Small molecule interactions, Signal transduction, Other]
Pssm-ID: 272984 [Multi-domain] Cd Length: 165 Bit Score: 124.37 E-value: 7.47e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 277 TLHDPLTHLLNGGSFIQTVDRAIGQART-GEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRA-VLDDDLPlARY 354
Cdd:TIGR00254 2 AVRDPLTGLYNRRYLEEMLDSELKRARRfQRSFSVLMIDIDNFKKINDTLGHDVGDEVLREVARILQSsVRGSDVV-GRY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 355 AGDEFSLLLPLGQRGDSQPLAMRLLEQLRP-PFELAG-QRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNR 432
Cdd:TIGR00254 81 GGEEFVVILPGTPLEDALSKAERLRDAINSkPIEVAGsETLTVTVSIGVACYPGHGLTLEELLKRADEALYQAKKAGRNR 160
|
.
gi 2527447185 433 S 433
Cdd:TIGR00254 161 V 161
|
|
| T2SS_HK |
NF038348 |
histidine kinase; |
20-276 |
8.70e-28 |
|
histidine kinase;
Pssm-ID: 439642 [Multi-domain] Cd Length: 574 Bit Score: 118.51 E-value: 8.70e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 20 YESLLVVLAYLIASAAGYTALAMADWVT---NSRSRRGSELAkliGAVALGGGIWSMHFLAMLSFKIGIHVHYAPLQTLA 96
Cdd:NF038348 5 YDLSLVLLSLVIATLASYTALDLSALISlldKPRLRRAWLAG---GAAAMGTGIWAMHFVGMLAFSLPIPLGYDLRETGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 97 SLLIAIAVSYTVMHLIGRESLTAPQYGLAALAAGLGIATMHYTGMLAMQSVAVQLYDPLLVVVSVVVASLASLGALLLAF 176
Cdd:NF038348 82 SLAIAMVVSYFALNAVTRAKLTRERLAAGGVLMGLGIAGMHYTGMAALQMQPGIRYDSALFVASIGIAILASTAALWLAH 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 177 RLRGRTGLRTFWLRLLGSLVLGFAIVSMHFTGMAALTlavpigFEPGGLAEANQHLE---LGMGIALGTLFIIMVGLLAA 253
Cdd:NF038348 162 RLRTENAGRVIVKRIGAATVMGVAITGMHYTGMAAAH------FAPNARCGAANGISgpwLGTTIALFTATILIVTLVIS 235
|
250 260
....*....|....*....|...
gi 2527447185 254 wageRFNAQRLRLERVSTTLDQI 276
Cdd:NF038348 236 ----RFDARTMFLRGITDALEDL 254
|
|
| pleD |
PRK09581 |
response regulator PleD; Reviewed |
280-432 |
3.72e-24 |
|
response regulator PleD; Reviewed
Pssm-ID: 236577 [Multi-domain] Cd Length: 457 Bit Score: 106.14 E-value: 3.72e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 280 DPLTHLLN----GGSFIQTVDRAIGQARTgeqFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRA-VLDDDLPlARY 354
Cdd:PRK09581 295 DGLTGLHNrryfDMHLKNLIERANERGKP---LSLMMIDIDHFKKVNDTYGHDAGDEVLREFAKRLRNnIRGTDLI-ARY 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 355 AGDEFSLLLPlgqrgDSQP-LAMRLLEQLR-----PPFELAGQ--RIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCK 426
Cdd:PRK09581 371 GGEEFVVVMP-----DTDIeDAIAVAERIRrkiaeEPFIISDGkeRLNVTVSIGVAELRPSGDTIEALIKRADKALYEAK 445
|
....*.
gi 2527447185 427 RSGRNR 432
Cdd:PRK09581 446 NTGRNR 451
|
|
| PRK09894 |
PRK09894 |
diguanylate cyclase; Provisional |
257-432 |
4.90e-20 |
|
diguanylate cyclase; Provisional
Pssm-ID: 182133 [Multi-domain] Cd Length: 296 Bit Score: 91.28 E-value: 4.90e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 257 ERFNAQRLRLERVSTTLdqITLHDPLTHLLNGGSFIQTVDRAIGQaRTGEQFALLMLDIDHFKRINDSLGHALGDELLIQ 336
Cdd:PRK09894 111 LSFTAALTDYKIYLLTI--RSNMDVLTGLPGRRVLDESFDHQLRN-REPQNLYLALLDIDRFKLVNDTYGHLIGDVVLRT 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 337 MAQRIRAVLDDDLPLARYAGDEFSLLLPlgQRGDSQplAMRLLEQLRP-----PFELAGQRIAMTFSLGIAHypqdgANA 411
Cdd:PRK09894 188 LATYLASWTRDYETVYRYGGEEFIICLK--AATDEE--ACRAGERIRQlianhAITHSDGRINITATFGVSR-----AFP 258
|
170 180
....*....|....*....|....*
gi 2527447185 412 GQLLRS----AGLAVGHCKRSGRNR 432
Cdd:PRK09894 259 EETLDVvigrADRAMYEGKQTGRNR 283
|
|
| PRK09966 |
PRK09966 |
diguanylate cyclase DgcN; |
263-402 |
4.47e-19 |
|
diguanylate cyclase DgcN;
Pssm-ID: 182171 [Multi-domain] Cd Length: 407 Bit Score: 90.07 E-value: 4.47e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 263 RLRLERVSTTLDQITLHDPLTHLLNGGSFIQTVDRAIGQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIR 342
Cdd:PRK09966 234 QLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDARKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLA 313
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2527447185 343 AVLDDDLPLARYAGDEFSLLL-PLGQRGDSQPLAMRLLEQLRPPFEL-AGQRIAMTFSLGIA 402
Cdd:PRK09966 314 EFGGLRHKAYRLGGDEFAMVLyDVQSESEVQQICSALTQIFNLPFDLhNGHQTTMTLSIGYA 375
|
|
| PRK15426 |
PRK15426 |
cellulose biosynthesis regulator YedQ; |
271-432 |
1.45e-18 |
|
cellulose biosynthesis regulator YedQ;
Pssm-ID: 237964 [Multi-domain] Cd Length: 570 Bit Score: 89.69 E-value: 1.45e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 271 TTLDQITLHDPLTHLLNGGSFI-QTVDRAIGQARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVL-DDD 348
Cdd:PRK15426 392 SSLQWQAWHDPLTRLYNRGALFeKARALAKRCQRDQQPFSVIQLDLDHFKSINDRFGHQAGDRVLSHAAGLISSSLrAQD 471
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 349 LPlARYAGDEFSLLLPLGQRGDSQPLA--MRLLEQLRPPFELAGQRIAMTFSLGIAHYPQDGA-NAGQLLRSAGLAVGHC 425
Cdd:PRK15426 472 VA-GRVGGEEFCVVLPGASLAEAAQVAerIRLRINEKEILVAKSTTIRISASLGVSSAEEDGDyDFEQLQSLADRRLYLA 550
|
....*..
gi 2527447185 426 KRSGRNR 432
Cdd:PRK15426 551 KQAGRNR 557
|
|
| PRK11059 |
PRK11059 |
regulatory protein CsrD; Provisional |
301-689 |
6.62e-18 |
|
regulatory protein CsrD; Provisional
Pssm-ID: 236833 [Multi-domain] Cd Length: 640 Bit Score: 88.00 E-value: 6.62e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 301 QARTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVLDD--DLPLARYAGDEFSLLLPlgQRG--DSQPLAM 376
Cdd:PRK11059 253 QEMVGAHGVVMLIRLPDFDLLQEEWGESQVEELLFELINLLSTFVMRypGALLARYSRSDFAVLLP--HRSlkEADSLAS 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 377 RLLEQL-RPPFELAGQRIAMtFSLGIAHYpQDGANAGQLLRSAGLAVGHCKRSGRNRSQRFttelqrdaDDLLSLEMD-- 453
Cdd:PRK11059 331 QLLKAVdALPPPKMLDRDDF-LHIGICAY-RSGQSTEQVMEEAEMALRSAQLQGGNGWFVY--------DKAQLPEKGrg 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 454 -------LRQALAQGGLHVAYQPIVDPAGAPVALEALVRWQHPVLGPLSPERFVRVAEETGLIADLDGWVMRQACADLAQ 526
Cdd:PRK11059 401 svrwrtlLEQTLVRGGPRLYQQPAVTRDGKVHHRELFCRIRDGQGELLSAELFMPMVQQLGLSEQYDRQVIERVLPLLRY 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 527 LhreghaamrvSVNCSALNLS-DRLLPQSIAR-----ALQAEDLPASALILEVTENALMHSLNVAVEVLGEIRTLGVRVS 600
Cdd:PRK11059 481 W----------PEENLSINLSvDSLLSRAFQRwlrdtLLQCPRSQRKRLIFELAEADVCQHISRLRPVLRMLRGLGCRLA 550
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 601 IDDFGSGYSSLAYLSRLPVDSLKVDRAFVRTIPKQSNDMAIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQG 680
Cdd:PRK11059 551 VDQAGLTVVSTSYIKELNVELIKLHPSLVRNIHKRTENQLFVRSLVGACAGTETQVFATGVESREEWQTLQELGVSGGQG 630
|
....*....
gi 2527447185 681 YLFGRPMPL 689
Cdd:PRK11059 631 DFFAESQPL 639
|
|
| adrA |
PRK10245 |
diguanylate cyclase AdrA; Provisional |
303-434 |
3.03e-13 |
|
diguanylate cyclase AdrA; Provisional
Pssm-ID: 182329 [Multi-domain] Cd Length: 366 Bit Score: 71.78 E-value: 3.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 303 RTGEQFALLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVLDDDLPLARYAGDEFSLLLPlGQRGDSQPLAM-RLLEQ 381
Cdd:PRK10245 232 RHHRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMS-GTPAESAITAMsRVHEG 310
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 2527447185 382 LRPPFELAGQRIAMTFSLGIAHYPQDGANAGQLLRSAGLAVGHCKRSGRNRSQ 434
Cdd:PRK10245 311 LNTLRLPNAPQVTLRISVGVAPLNPQMSHYREWLKSADLALYKAKNAGRNRTE 363
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
68-121 |
2.00e-11 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 59.53 E-value: 2.00e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 2527447185 68 GGIWSMHFLAMLSFKIGIHVHYAPLQTLASLLIAIAVSYTVMHLIGRESLTAPQ 121
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTALSLVIAVVASGAALWLAFRRRDTRLR 54
|
|
| Nucleotidyl_cyc_III |
cd07556 |
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse ... |
310-412 |
1.92e-08 |
|
Class III nucleotidyl cyclases; Class III nucleotidyl cyclases are the largest, most diverse group of nucleotidyl cyclases (NC's) containing prokaryotic and eukaryotic proteins. They can be divided into two major groups; the mononucleotidyl cyclases (MNC's) and the diguanylate cyclases (DGC's). The MNC's, which include the adenylate cyclases (AC's) and the guanylate cyclases (GC's), have a conserved cyclase homology domain (CHD), while the DGC's have a conserved GGDEF domain, named after a conserved motif within this subgroup. Their products, cyclic guanylyl and adenylyl nucleotides, are second messengers that play important roles in eukaryotic signal transduction and prokaryotic sensory pathways.
Pssm-ID: 143637 [Multi-domain] Cd Length: 133 Bit Score: 53.51 E-value: 1.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 310 LLMLDIDHFKRINDSLGHALGDELLIQMAQRIRAVLDD--DLPlARYAGDEFSLLLPLGQRGDSQPLAMRLLEQLRppfE 387
Cdd:cd07556 4 ILFADIVGFTSLADALGPDEGDELLNELAGRFDSLIRRsgDLK-IKTIGDEFMVVSGLDHPAAAVAFAEDMREAVS---A 79
|
90 100
....*....|....*....|....*.
gi 2527447185 388 LAGQRIA-MTFSLGIAHYPQDGANAG 412
Cdd:cd07556 80 LNQSEGNpVRVRIGIHTGPVVVGVIG 105
|
|
| YuxH |
COG3434 |
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction ... |
539-689 |
8.91e-08 |
|
c-di-GMP phosphodiesterase YuxH/PdeH, contains EAL and HDOD domains [Signal transduction mechanisms];
Pssm-ID: 442660 [Multi-domain] Cd Length: 407 Bit Score: 54.81 E-value: 8.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 539 VNCSALNLSDRLLpqsiaralqaEDLPASALILEVTENALMHslNVAVEVLGEIRTLGVRVSIDDFGSGYSSLAYLSRlp 618
Cdd:COG3434 66 INFTEELLLSDLP----------ELLPPERVVLEILEDVEPD--EELLEALKELKEKGYRIALDDFVLDPEWDPLLPL-- 131
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2527447185 619 VDSLKVDrafVRTIPKQsndmaIAAAIIAMAHKLGLNVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPL 689
Cdd:COG3434 132 ADIIKID---VLALDLE-----ELAELVARLKRYGIKLLAEKVETREEFELCKELGFDLFQGYFFSKPEIL 194
|
|
| PRK11596 |
PRK11596 |
cyclic-di-GMP phosphodiesterase; Provisional |
467-694 |
5.38e-07 |
|
cyclic-di-GMP phosphodiesterase; Provisional
Pssm-ID: 183222 [Multi-domain] Cd Length: 255 Bit Score: 51.54 E-value: 5.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 467 YQPIVDPAGAPVALEALVRWQHPvLGP---LSPER-FVRVAEETGLIadldgwVMRQACADLAQLH-REGHAAMRVSVNC 541
Cdd:PRK11596 34 FQPIYRTSGRLMAIELLTAVTHP-SNPsqrLSPERyFAEITVSHRLD------VVKEQLDLLAQWAdFFVRHGLLASVNI 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 542 SALNLSdrllpqsiarALQaEDLPASALI-------LEVTENALMhSLNVAVEVLGEIRTLGvrvsIDDFGSGYSSLAYL 614
Cdd:PRK11596 107 DGPTLI----------ALR-QQPAILRLIerlpwlrFELVEHIRL-PKDSPFASMCEFGPLW----LDDFGTGMANFSAL 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2527447185 615 SRLPVDSLKVDRAfVRTIPKQS---NDMAIAAAIIAMAHKLGlnVVAEGVETSEQRQFLQANGCNFMQGYLFGRPMPLPQ 691
Cdd:PRK11596 171 SEVRYDYIKVARE-LFIMLRQSeegRNLFSQLLHLMNRYCRG--VIVEGVETPEEWRDVQRSPAFAAQGYFLSRPAPFET 247
|
...
gi 2527447185 692 LRT 694
Cdd:PRK11596 248 LET 250
|
|
| MHYT |
pfam03707 |
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat ... |
199-249 |
8.62e-04 |
|
Bacterial signalling protein N terminal repeat; Found as an N terminal triplet tandem repeat in bacterial signalling proteins. Family includes CoxC and CoxH from P.carboxydovorans. Each repeat contains two transmembrane helices. Domain is also described as the MHYT domain.
Pssm-ID: 427453 [Multi-domain] Cd Length: 54 Bit Score: 37.96 E-value: 8.62e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 2527447185 199 FAIVSMHFTGMAALTLAVPIGFEPGGLAeanqhLELGMGIALGTLFIIMVG 249
Cdd:pfam03707 1 LGIWSMHFIGMLAFRLPGPIGYDPALTA-----LSLVIAVVASGAALWLAF 46
|
|
| |
