|
Name |
Accession |
Description |
Interval |
E-value |
| dnaA |
PRK00149 |
chromosomal replication initiator protein DnaA; |
161-435 |
1.72e-138 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 234667 [Multi-domain] Cd Length: 401 Bit Score: 402.59 E-value: 1.72e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:PRK00149 66 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:PRK00149 146 NALRN-----NTMEEFKEKYRSVDVlliddiqflagkertqeeffhtfnalheagkqivltsdrppkelpgleerlrsrf 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDF 335
Cdd:PRK00149 221 ewgltvdiepPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 336 FT-TDVEVKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISD 414
Cdd:PRK00149 301 LAaQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEK 380
|
330 340
....*....|....*....|.
gi 2525772056 415 EMREKQEIYNYVMELTVRLKQ 435
Cdd:PRK00149 381 LLEEDPELKEDVEELKRKLKS 401
|
|
| DnaA |
TIGR00362 |
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ... |
17-433 |
4.01e-132 |
|
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273037 [Multi-domain] Cd Length: 437 Bit Score: 387.66 E-value: 4.01e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 17 WSDALAILhSSTLSARE-KGWFEDVVPEAVFGTTIVLCVSNAEVQQTLQTTLNESLMNALRIASGQEMFPAFKIAPAVEE 95
Cdd:TIGR00362 1 WNRILERL-EKELSEQEyNTWFKPLKLLSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 96 rpaaqPERPHAKPVRHEERTPEAPSAFdpyagktsvqgqlpipamipsqsfesgergpaldpeTHLNKNATFDTFVPGDS 175
Cdd:TIGR00362 80 -----LEPNSKKPEPAPPEAPAPPSSA------------------------------------SGLNPKYTFDNFVVGKS 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 176 NRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFIDALQNpsqsqGRIAE 255
Cdd:TIGR00362 119 NRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRN-----NKMEE 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 256 FNRRYRQVDV-----------------------------------------------------------------PDLET 270
Cdd:TIGR00362 194 FKEKYRSVDLlliddiqflagkertqeeffhtfnalhennkqivltsdrppkelpgledrlrsrfewglvvdiepPDLET 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 271 RIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDFF-TTDVEVKPSDIIG 349
Cdd:TIGR00362 274 RLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGALNRLLAYASLTGKPITLELAKEALKDLLrAQKKEITIENIQK 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 350 QVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISDEMREKQEIYNYVMEL 429
Cdd:TIGR00362 354 VVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEEL 433
|
....
gi 2525772056 430 TVRL 433
Cdd:TIGR00362 434 KRKL 437
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
161-402 |
1.17e-109 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 325.22 E-value: 1.17e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:COG0593 1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:COG0593 81 NAIRN-----NTIEEFKEKYRSVDVlliddiqflagkeatqeeffhtfnalreagkqivltsdrppkelpgleerlrsrl 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDF 335
Cdd:COG0593 156 ewglvvdiqpPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDL 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525772056 336 FT-TDVEVKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDH 402
Cdd:COG0593 236 LRaQKKEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
161-318 |
1.29e-58 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 191.39 E-value: 1.29e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:pfam00308 1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:pfam00308 81 DAIRD-----NKTNQFKEKYRNVDVlliddiqflagkegtqeeffhtfnalhesgkqivfssdrppkeleeledrlrsrf 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASL 318
Cdd:pfam00308 156 qwglvtdiepPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSL 218
|
|
| Bac_DnaA_C |
cd06571 |
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ... |
344-433 |
2.27e-36 |
|
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.
Pssm-ID: 119330 [Multi-domain] Cd Length: 90 Bit Score: 128.40 E-value: 2.27e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 344 PSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISDEMREKQEIY 423
Cdd:cd06571 1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
|
90
....*....|
gi 2525772056 424 NYVMELTVRL 433
Cdd:cd06571 81 EDVEELEKKL 90
|
|
| Bac_DnaA_C |
smart00760 |
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding. |
344-411 |
8.01e-30 |
|
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
Pssm-ID: 197863 [Multi-domain] Cd Length: 69 Bit Score: 110.29 E-value: 8.01e-30
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525772056 344 PSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTR 411
Cdd:smart00760 2 IEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dnaA |
PRK00149 |
chromosomal replication initiator protein DnaA; |
161-435 |
1.72e-138 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 234667 [Multi-domain] Cd Length: 401 Bit Score: 402.59 E-value: 1.72e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:PRK00149 66 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:PRK00149 146 NALRN-----NTMEEFKEKYRSVDVlliddiqflagkertqeeffhtfnalheagkqivltsdrppkelpgleerlrsrf 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDF 335
Cdd:PRK00149 221 ewgltvdiepPDLETRIAILKKKAEEEGIDLPDEVLEFIAKNITSNVRELEGALNRLIAYASLTGKPITLELAKEALKDL 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 336 FT-TDVEVKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISD 414
Cdd:PRK00149 301 LAaQKKKITIENIQKVVAEYYNIKVSDLKSKSRTRNIARPRQIAMYLAKELTDLSLPEIGRAFGGRDHTTVLHAVRKIEK 380
|
330 340
....*....|....*....|.
gi 2525772056 415 EMREKQEIYNYVMELTVRLKQ 435
Cdd:PRK00149 381 LLEEDPELKEDVEELKRKLKS 401
|
|
| DnaA |
TIGR00362 |
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ... |
17-433 |
4.01e-132 |
|
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273037 [Multi-domain] Cd Length: 437 Bit Score: 387.66 E-value: 4.01e-132
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 17 WSDALAILhSSTLSARE-KGWFEDVVPEAVFGTTIVLCVSNAEVQQTLQTTLNESLMNALRIASGQEMFPAFKIAPAVEE 95
Cdd:TIGR00362 1 WNRILERL-EKELSEQEyNTWFKPLKLLSIEGNTLIISVPNEFVKEWIEKNYLDLIEELLQELFGAEIEIEFTVGEDEEE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 96 rpaaqPERPHAKPVRHEERTPEAPSAFdpyagktsvqgqlpipamipsqsfesgergpaldpeTHLNKNATFDTFVPGDS 175
Cdd:TIGR00362 80 -----LEPNSKKPEPAPPEAPAPPSSA------------------------------------SGLNPKYTFDNFVVGKS 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 176 NRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFIDALQNpsqsqGRIAE 255
Cdd:TIGR00362 119 NRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFVNALRN-----NKMEE 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 256 FNRRYRQVDV-----------------------------------------------------------------PDLET 270
Cdd:TIGR00362 194 FKEKYRSVDLlliddiqflagkertqeeffhtfnalhennkqivltsdrppkelpgledrlrsrfewglvvdiepPDLET 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 271 RIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDFF-TTDVEVKPSDIIG 349
Cdd:TIGR00362 274 RLAILQKKAEEEGLELPDEVLEFIAKNITSNVRELEGALNRLLAYASLTGKPITLELAKEALKDLLrAQKKEITIENIQK 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 350 QVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISDEMREKQEIYNYVMEL 429
Cdd:TIGR00362 354 VVAKYYNIKVSDLKSKKRTRNIVRPRQIAMYLAKELTDLSLPEIGKAFGGRDHTTVLHAVRKIEKLIETDAELKEDIEEL 433
|
....
gi 2525772056 430 TVRL 433
Cdd:TIGR00362 434 KRKL 437
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
161-402 |
1.17e-109 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 325.22 E-value: 1.17e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:COG0593 1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:COG0593 81 NAIRN-----NTIEEFKEKYRSVDVlliddiqflagkeatqeeffhtfnalreagkqivltsdrppkelpgleerlrsrl 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDF 335
Cdd:COG0593 156 ewglvvdiqpPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLKDL 235
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525772056 336 FT-TDVEVKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDH 402
Cdd:COG0593 236 LRaQKKEITIEDIQKAVAEYFGVSVADLLSKSRTREIARPRQIAMYLARELTDLSLPEIGRAFGGRDH 303
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
96-436 |
2.79e-96 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 301.74 E-value: 2.79e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 96 RPAAQPERPHAKPVRHEERTPEAP--SAFDPYAGKTSVQ-GQLPIPAMIPSQ-SFESGERGPAL---DPETHLNKNATFD 168
Cdd:PRK14086 209 RDYDHPRPDWDRPRRDRTDRPEPPpgAGHVHRGGPGPPErDDAPVVPIRPSApGPLAAQPAPAPgpgEPTARLNPKYTFD 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 169 TFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFIDALQNpsq 248
Cdd:PRK14086 289 TFVIGASNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYARRLYPGTRVRYVSSEEFTNEFINSIRD--- 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 249 sqGRIAEFNRRYRQVDV--------------------------------------------------------------- 265
Cdd:PRK14086 366 --GKGDSFRRRYREMDIllvddiqfledkestqeeffhtfntlhnankqivlssdrppkqlvtledrlrnrfewglitdv 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 266 --PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASLSNQPVTKALAEQTLQDFFTTDV--E 341
Cdd:PRK14086 444 qpPELETRIAILRKKAVQEQLNAPPEVLEFIASRISRNIRELEGALIRVTAFASLNRQPVDLGLTEIVLRDLIPEDSapE 523
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 342 VKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFgGRDHTTVMHACTRISDEMREKQE 421
Cdd:PRK14086 524 ITAAAIMAATADYFGLTVEDLCGTSRSRVLVTARQIAMYLCRELTDLSLPKIGQQF-GRDHTTVMHADRKIRALMAERRS 602
|
410
....*....|....*
gi 2525772056 422 IYNYVMELTVRLKQR 436
Cdd:PRK14086 603 IYNQVTELTNRIKNG 617
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
161-318 |
1.29e-58 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 191.39 E-value: 1.29e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVKDPTLKVRYVTSEEFTNEFI 240
Cdd:pfam00308 1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 241 DALQNpsqsqGRIAEFNRRYRQVDV------------------------------------------------------- 265
Cdd:pfam00308 81 DAIRD-----NKTNQFKEKYRNVDVlliddiqflagkegtqeeffhtfnalhesgkqivfssdrppkeleeledrlrsrf 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2525772056 266 ----------PDLETRIAILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAVASL 318
Cdd:pfam00308 156 qwglvtdiepPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVRELEGALNRLLAYSSL 218
|
|
| Bac_DnaA_C |
cd06571 |
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA ... |
344-433 |
2.27e-36 |
|
C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple copies of DnaA, which is an ATPase, bind to 9-mers at the origin and form an initial complex in which the DNA strands are being separated in an ATP-dependent step.
Pssm-ID: 119330 [Multi-domain] Cd Length: 90 Bit Score: 128.40 E-value: 2.27e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 344 PSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRISDEMREKQEIY 423
Cdd:cd06571 1 IELIIEAVAEYFGISVEDLRSKSRKKEIALARQIAMYLARELTGLSLPEIGRAFGGRDHSTVLHAVRKIEELLEEDPELK 80
|
90
....*....|
gi 2525772056 424 NYVMELTVRL 433
Cdd:cd06571 81 EDVEELEKKL 90
|
|
| Bac_DnaA_C |
pfam08299 |
Bacterial dnaA protein helix-turn-helix; |
344-412 |
1.41e-34 |
|
Bacterial dnaA protein helix-turn-helix;
Pssm-ID: 462419 [Multi-domain] Cd Length: 69 Bit Score: 122.90 E-value: 1.41e-34
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2525772056 344 PSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTRI 412
Cdd:pfam08299 1 IEKIIEAVAEYFGISPEDLKSKSRKREIALARQIAMYLARELTDLSLPEIGRAFGGRDHSTVIHACKKI 69
|
|
| PRK12422 |
PRK12422 |
chromosomal replication initiator protein DnaA; |
161-433 |
4.73e-32 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 183521 [Multi-domain] Cd Length: 445 Bit Score: 126.49 E-value: 4.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 161 LNKNATFDTFVPGDSNRFARTVALAVA----EGSGQDFNPLCIYGGSGLGKTHLLNAIGNyaLVKDPTLKVRYVTSEEFT 236
Cdd:PRK12422 104 LDPLMTFANFLVTPENDLPHRILQEFTkvseQGKGFPFNPIYLFGPEGSGKTHLMQAAVH--ALRESGGKILYVRSELFT 181
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 237 NEFIDALQNpsqsqGRIAEFNRRYRQVDVP-------------------------DLETRIAIL--------------RM 277
Cdd:PRK12422 182 EHLVSAIRS-----GEMQRFRQFYRNVDALfiedievfsgkgatqeeffhtfnslHTEGKLIVIsstcapqdlkameeRL 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 278 MS----------------GMNGV----------TIPNDVLDLIAERFTENIRELEGALT----RVtAVASLSNQPVTKAL 327
Cdd:PRK12422 257 ISrfewgiaiplhpltkeGLRSFlerkaealsiRIEETALDFLIEALSSNVKSLLHALTllakRV-AYKKLSHQLLYVDD 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 328 AEQTLQDFFTTD--VEVKPSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFgGRDHTTV 405
Cdd:PRK12422 336 IKALLHDVLEAAesVRLTPSKIIRAVAQYYGVSPESILGRSQSREYVLPRQVAMYLCRQKLSLSYVKIGDVF-SRDHSTV 414
|
330 340
....*....|....*....|....*....
gi 2525772056 406 MHACTRISDEMRE-KQEIYNYVMELTVRL 433
Cdd:PRK12422 415 ISSIRAISQKLEEdDRDISMAIQEITKRL 443
|
|
| Bac_DnaA_C |
smart00760 |
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding. |
344-411 |
8.01e-30 |
|
Bacterial dnaA protein helix-turn-helix domain; Could be involved in DNA-binding.
Pssm-ID: 197863 [Multi-domain] Cd Length: 69 Bit Score: 110.29 E-value: 8.01e-30
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2525772056 344 PSDIIGQVAKYFHLTFDQIVGRTRTKNVALARQIAMYLSREMTSISLKDIGDVFGGRDHTTVMHACTR 411
Cdd:smart00760 2 IEEIIEAVAEYFGVKPEDLKSKSRKREIVLARQIAMYLARELTDLSLPEIGKIFGGRDHSTVLHACRK 69
|
|
| DnaC |
COG1484 |
DNA replication protein DnaC [Replication, recombination and repair]; |
160-265 |
9.62e-10 |
|
DNA replication protein DnaC [Replication, recombination and repair];
Pssm-ID: 441093 [Multi-domain] Cd Length: 242 Bit Score: 58.64 E-value: 9.62e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 160 HLNKNATFDTFVPGDSNRFARTVALAVAEGsgqDF----NPLCIYGGSGLGKTHLLNAIGNYALVKDptLKVRYVTseef 235
Cdd:COG1484 64 RFPAAKTLEDFDFDAQPGLDRRQILELATL---DFiergENLILLGPPGTGKTHLAIALGHEACRAG--YRVRFTT---- 134
|
90 100 110
....*....|....*....|....*....|
gi 2525772056 236 TNEFIDALQNpSQSQGRIAEFNRRYRQVDV 265
Cdd:COG1484 135 APDLVNELKE-ARADGRLERLLKRLAKVDL 163
|
|
| PRK06030 |
PRK06030 |
hypothetical protein; Provisional |
351-435 |
1.05e-09 |
|
hypothetical protein; Provisional
Pssm-ID: 180356 Cd Length: 124 Bit Score: 55.94 E-value: 1.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 351 VAKYFHLTFDQIVGRTRTKN-VALARQIAMYLSREMTSISLKDIGDVFGgRDHTTVMHACTRISDeMREKQEIYNYVMEL 429
Cdd:PRK06030 32 LALAFGVSGAEIASPLRGRReVSRIRQIAMYVAHVSLGWPMNEVALAFG-RDRTTVGHACHTVED-LRDDAAFDARVSVL 109
|
....*.
gi 2525772056 430 TVRLKQ 435
Cdd:PRK06030 110 ERIVNS 115
|
|
| DnaA_homol_Hda |
TIGR03420 |
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ... |
165-333 |
1.33e-09 |
|
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 274571 [Multi-domain] Cd Length: 226 Bit Score: 57.97 E-value: 1.33e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 165 ATFDTFVPGdSNRFARTVALAVAEGSGQDFnpLCIYGGSGLGKTHLLNAIGNYALVKDptLKVRYVTSEEFTNEFIDALQ 244
Cdd:TIGR03420 12 PTFDNFYAG-GNAELLAALRQLAAGKGDRF--LYLWGESGSGKSHLLQAACAAAEERG--KSAIYLPLAELAQADPEVLE 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 245 NPSQSQ-------GRIAE-----------FNRRY--------------RQVDV--PDLETR-----------------IA 273
Cdd:TIGR03420 87 GLEQADlvclddvEAIAGqpewqealfhlYNRVReaggrlliagraapAQLPLrlPDLRTRlawglvfqlpplsdeekIA 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2525772056 274 ILRMMSGMNGVTIPNDVLDLIAERFTENIRELEGALTRVTAvASLSNQ-PVTKALAEQTLQ 333
Cdd:TIGR03420 167 ALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDR-ASLAAKrKITIPFVKEVLA 226
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
194-295 |
1.95e-05 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 44.44 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 194 FNPLCIYGGSGLGKTHLLNAIGNYALVKDptLKVRYVTSEEFTNEFIDALQNpSQSQGRIAEFNRRYRQVDV-------- 265
Cdd:cd00009 19 PKNLLLYGPPGTGKTTLARAIANELFRPG--APFLYLNASDLLEGLVVAELF-GHFLVRLLFELAEKAKPGVlfideids 95
|
90 100 110
....*....|....*....|....*....|
gi 2525772056 266 PDLETRIAILRMMSGMNGVTIPNDVLDLIA 295
Cdd:cd00009 96 LSRGAQNALLRVLETLNDLRIDRENVRVIG 125
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
195-245 |
8.62e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 39.66 E-value: 8.62e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 2525772056 195 NPLCIYGGSGLGKTHLLNAIGNYAlvKDPTLKVRYVTSEEFTNEFIDALQN 245
Cdd:smart00382 3 EVILIVGPPGSGKTTLARALAREL--GPPGGGVIYIDGEDILEEVLDQLLL 51
|
|
| PRK12377 |
PRK12377 |
putative replication protein; Provisional |
161-221 |
3.01e-03 |
|
putative replication protein; Provisional
Pssm-ID: 183482 [Multi-domain] Cd Length: 248 Bit Score: 39.05 E-value: 3.01e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2525772056 161 LNKNATFDTF-VPGDSNRFARTVALAVAEGSGQDFNPLCIYGGSGLGKTHLLNAIGNYALVK 221
Cdd:PRK12377 67 LHRKCSFANYqVQNDGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAK 128
|
|
| PRK08903 |
PRK08903 |
DnaA regulatory inactivator Hda; Validated |
165-335 |
3.68e-03 |
|
DnaA regulatory inactivator Hda; Validated
Pssm-ID: 236347 [Multi-domain] Cd Length: 227 Bit Score: 38.80 E-value: 3.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 165 ATFDTFVPGdSNRFARTVALAVAEGSGQDfNPLCIYGGSGLGKTHLLNAIGNYALVKDptLKVRYVTS----EEFTNEF- 239
Cdd:PRK08903 15 PTFDNFVAG-ENAELVARLRELAAGPVAD-RFFYLWGEAGSGRSHLLQALVADASYGG--RNARYLDAasplLAFDFDPe 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2525772056 240 --------IDALQNPSQsqgrIAEFN--RRYR----------------QVDV-PDLETR-----------------IAIL 275
Cdd:PRK08903 91 aelyavddVERLDDAQQ----IALFNlfNRVRahgqgallvagpaaplALPLrEDLRTRlgwglvyelkplsdadkIAAL 166
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2525772056 276 RMMSGMNGVTIPNDVLDLIAERFTENIRELEG---ALTRvtavASLSNQ-PVTKALAEQTLQDF 335
Cdd:PRK08903 167 KAAAAERGLQLADEVPDYLLTHFRRDMPSLMAlldALDR----YSLEQKrPVTLPLLREMLAQP 226
|
|
| |
