|
Name |
Accession |
Description |
Interval |
E-value |
| PRK13564 |
PRK13564 |
anthranilate synthase component 1; |
5-533 |
0e+00 |
|
anthranilate synthase component 1;
Pssm-ID: 237428 [Multi-domain] Cd Length: 520 Bit Score: 903.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 5 TTEQDGNLETLRVSLPYQAEPLQVYQNTCQTNGAHLLLDSADIGTKQQVKSLLLIDAALQLTCNEQQVTIQALTDNGNAL 84
Cdd:PRK13564 1 MQTQKPTLELLTCKAPYREDPTALFHQLCGDRPATLLLESAEIDSKDNLKSLLLVDSALRITCLGNTVTIQALTDNGAAL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 85 LPWIQKKLESCATITALGNGLVADFTLAAPSQgdvpvDEDSRLRQISNMEPLRILQQQLmkanDTAQKHPFSVFLGGAFA 164
Cdd:PRK13564 81 LPLLDEALPAGVENEQDPNGLVLTFPPVSPLL-----DEDARLKSLSVFDALRLLQKLV----NTPKEEREALFLGGLFA 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 165 YDFVASYEPLPQVEEGENdCPDYVFYLAETLLIIDHQAQTTELLGSVFGgkDHDKRYQAMSQRVGELAArcQLPAItPEP 244
Cdd:PRK13564 152 YDLVAGFEPLPQLPAGNN-CPDYCFYLAETLLVIDHQKKSARLQASLFT--PDEEEKQRLAARLAQLKQ--QLTQP-APP 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 245 LPV----DVSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCPEPLAAYNQLKKNNPSPYMFFMSHPDFCLFG 320
Cdd:PRK13564 226 LPVtsvpDMEVSVNISDEEFCAVVRKLKEHIRAGDIFQVVPSRRFSLPCPSPLAAYRVLKKSNPSPYMFYMQDEDFTLFG 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 321 ASPESALKYQKDSNQVELYPIAGTRPRGKNADGSINLDLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVA 400
Cdd:PRK13564 306 ASPESALKYDASSRQVEIYPIAGTRPRGRRADGSIDRDLDSRIELELRTDHKELAEHLMLVDLARNDLARICQPGSRYVA 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 401 DLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTC 480
Cdd:PRK13564 386 DLLKVDRYSHVMHLVSRVVGELRHDLDALHAYRACMNMGTLTGAPKVRAMQLIREVEGQRRGSYGGAVGYLTGHGDLDTC 465
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 2524968378 481 IVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQQAHSVQE 533
Cdd:PRK13564 466 IVIRSAFVENGIATVQAGAGVVLDSDPQSEADETRNKAQAVLRAIATAHHAQE 518
|
|
| trpE_proteo |
TIGR00565 |
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other ... |
21-529 |
0e+00 |
|
anthranilate synthase component I, proteobacterial subset; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. This group includes proteobacteria such as E. coli and Helicobacter pylori but also the gram-positive organism Corynebacterium glutamicum. The second group includes eukaryotes, archaea, and most other bacterial lineages; sequences from the second group may resemble pabB more closely than other trpE from this group. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273143 [Multi-domain] Cd Length: 498 Bit Score: 616.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 21 YQAEPLQVYQNTCQTNGAHLLLDSADIGTKQQVKSLLLIDAALQLTCNEQQVTIQALTDNGNALLPWIQKKLESCATITA 100
Cdd:TIGR00565 1 YIPYPTALFEKLCQSNPHTLLLESAEIESKAHLKSLLLVKAALKITCLGNIVTITALTPNGGAFLQKLSAFLKAPVSAVI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 101 LGNGLVADFTLAAPSQgdvpvDEDSRLRQISNMEPLRILQQQLMKAndtaqKHPFSVFLGGAFAYDFVASYEPLPQVEEG 180
Cdd:TIGR00565 81 QDNALILTFTPNKKTL-----DEDLKLFSPSPFDALRLFKSLKTKP-----KHPFTLFSGGLFSYDLVAFFEDLPHLKAK 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 181 ENDCPDYVFYLAETLLIIDHQAQTTELLGSVFGGKDHDKRYQAMsQRVGELAARCQLPAITPEPLPVDvSVTATPSADEF 260
Cdd:TIGR00565 151 NNNCPDFIFYLAENLIIIDHQEKSVEILGACFAERFETQIAQAL-QDLKELQKSIKSDFVPKKSKQSR-EVSANCSDSEF 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 261 ASIVTQLKKNIVAGDIFQVVPSRRFKMPCPEPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKDSNQVELYP 340
Cdd:TIGR00565 229 EGRVLSLQEEIKKGEIFQAVPSRRFSLECPEGLAAYYHLKLTNPSPYMFYMKDSDFILFGASPESALKYNALTRQAEIYP 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 341 IAGTRPRGKNADGSINLDLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVA 420
Cdd:TIGR00565 309 IAGTRPRGKDAQGNIDYDLDSRMELELRHDHKERAEHLMLVDLARNDMARVCKSGKRYVAKLLKVDRYSNVMHLVSRVVG 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 421 KLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAG 500
Cdd:TIGR00565 389 ELRKGLDALHAYRACMNMGTLSGAPKISAMQLIYQLENQRRGSYGGAVGYLTSEGSMDTCIVIRSAFVKNGRAVVQAGAG 468
|
490 500
....*....|....*....|....*....
gi 2524968378 501 VVHDSNPDSEVAETESKAKAVILAIQQAH 529
Cdd:TIGR00565 469 IVLDSVPQNEADETRAKAQAVLDAIRKTS 497
|
|
| TrpE |
COG0147 |
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, ... |
14-527 |
1.02e-169 |
|
Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Anthranilate/para-aminobenzoate synthases component I is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis
Pssm-ID: 439917 [Multi-domain] Cd Length: 416 Bit Score: 486.53 E-value: 1.02e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 14 TLRVSLPYQAEPLQVYQNTCQTNGAhLLLDSADIGTKQQVKSLLLIDAALQLTCNEQQVTIQALTDngnallpwiqkkle 93
Cdd:COG0147 4 PVYRELLALETPVSLFLKLADGPYA-FLLESAEGGEKWGRYSFIGADPLATLTVRGGRVTIEGGGE-------------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 94 scatitalgnglvadftlAAPSQGDvpvdedsrlrqisnmePLRILQQqLMKANDTAQKHPFSVFLGGA---FAYDFVAS 170
Cdd:COG0147 69 ------------------VEPSEGD----------------PLDALRA-LLARFRLPPLPGLPPFTGGLvgyFGYDLVRY 113
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 171 YEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTellgsvfggkdhdkryqamsqrvgelaarcqlPAITPEplpvdvs 250
Cdd:COG0147 114 FERLPDLAPDDLGLPDAALGLYDRLLVFDHLKGTR--------------------------------SNFTRE------- 154
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 251 vtatpsadEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCP-EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKY 329
Cdd:COG0147 155 --------EYLAAVERAKEYIRAGDIFQVVLSQRFSAPFEgDPLALYRALRRINPSPYMFYLRFGDFAIVGSSPERLVRV 226
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 330 qkDSNQVELYPIAGTRPRGKNADgsinldLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYS 409
Cdd:COG0147 227 --EDGRVETRPIAGTRPRGATPE------EDAALAEELLADEKERAEHLMLVDLARNDLGRVCEPGSVKVPELMVVERYS 298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 410 QVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVK 489
Cdd:COG0147 299 HVMHLVSTVTGRLRPGLDALDALRATFPAGTLTGAPKIRAMEIIDELEPTRRGVYGGAVGYLSFDGNMDLAIAIRTAVVK 378
|
490 500 510
....*....|....*....|....*....|....*...
gi 2524968378 490 NGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQQ 527
Cdd:COG0147 379 DGRAYVQAGAGIVADSDPEAEYQETLNKARALLRALEL 416
|
|
| trpE_most |
TIGR00564 |
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some ... |
135-526 |
1.37e-134 |
|
anthranilate synthase component I, non-proteobacterial lineages; This enzyme resembles some other chorismate-binding enzymes, including para-aminobenzoate synthase (pabB) and isochorismate synthase. There is a fairly deep split between two sets, seen in the pattern of gaps as well as in amino acid sequence differences. Archaeal enzymes have been excluded from this model (and are now found in TIGR01820) as have a clade of enzymes which constitute a TrpE paralog which may have PabB activity (TIGR01824). This allows the B. subtilus paralog which has been shown to have PabB activity to score below trusted to this model. This model contains sequences from gram-positive bacteria, certain proteobacteria, cyanobacteria, plants, fungi and assorted other bacteria.A second family of TrpE enzymes is modelled by TIGR00565. The breaking of the TrpE family into these diverse models allows for the separation of the models for the related enzyme, PabB. [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273142 [Multi-domain] Cd Length: 454 Bit Score: 398.63 E-value: 1.37e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 135 PLRILQQQLMKAN---DTAQKHPFSVFLGGAFAYDFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGSV 211
Cdd:TIGR00564 66 PLDEIRDVMETFAqhsDPELPIPFTGGAVGYLGYDTVRLFEKITLPPPDPLNLPDAYLMLCDDFIIFDHVTDKLYLIHNN 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 212 FGGKDHDKRYQAMsQRVGELAARCQLPAITPEPLPVD--VSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPC 289
Cdd:TIGR00564 146 RTTASRSAKAAAD-ARLEALVADLQDPLLPEVPVPYPaaLSFTSNYEKEEYEANVAKAKEYIKAGDIFQVVLSQRFEAKT 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 290 P-EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKdsNQVELYPIAGTRPRGKNADgsinldLDSRMELELR 368
Cdd:TIGR00564 225 EaPPFELYRVLRIVNPSPYMYYLDFGDFQIVGSSPELLVKVTG--GRITTRPIAGTRKRGATPE------EDEALAEELL 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 369 LDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVS 448
Cdd:TIGR00564 297 ADEKERAEHLMLVDLGRNDIGRVCEPGSVEVPEFMKIERYSHVMHIVSTVEGRLKDGLTAIDALRATFPAGTVSGAPKIR 376
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2524968378 449 AATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQ 526
Cdd:TIGR00564 377 AMELIDELEPEKRGIYGGAVGYLSFDGDMDTAIAIRTMVVKDGKAYVQAGGGIVADSDPEAEYEETLNKARALLRAIE 454
|
|
| PRK13571 |
PRK13571 |
anthranilate synthase component I; Provisional |
111-533 |
7.35e-111 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184152 [Multi-domain] Cd Length: 506 Bit Score: 339.69 E-value: 7.35e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 111 LAAPSQGdVPVDEDsrlrqisnmePLRILQQ--QLMKANDTAQKHPFSVFLGGAFAYDFVASYEPLPQVEEGENDCPDYV 188
Cdd:PRK13571 86 LGTPPAG-APTGGD----------PLAALRAtlELLATPRLPGLPPLTGGMVGFLGYDAVRRLERLPELAVDDLGLPEML 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 189 FYLAETLLIIDHQAQTTELLGSVFGGKDHDKRYQAMSQRvgelaARCQLPAITPE---PLPVDVSVTATP--------SA 257
Cdd:PRK13571 155 LLLATDLAAVDHHEGTITLIANAVNWNGTDERVDAAYDD-----AVARLDVMTAAlaqPLPSTVATFSRPvpefraqrTV 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 258 DEFASIVTQLKKNIVAGDIFQVVPSRRFKMPC-PEPLAAYNQLKKNNPSPYMFFMSHP------DFCLFGASPESALKYQ 330
Cdd:PRK13571 230 EEFGAAVEKLVEEIRAGEAFQVVPSQRFEMDTtADPLDVYRVLRVTNPSPYMYLLRVPnsdggtDFSIVGSSPEALVTVT 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 331 KDsnQVELYPIAGTRPRGKNADGsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQ 410
Cdd:PRK13571 310 DG--RATTHPIAGTRWRGATPEE------DALLEKELLADPKERAEHLMLVDLGRNDLGRVCRPGTVRVVDFSHIERYSH 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 411 VMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKN 490
Cdd:PRK13571 382 VMHLVSTVTGELAEGRTALDAVTACFPAGTLSGAPKVRAMELIEELEPTRRGLYGGVVGYLDFAGDADTAIAIRTALMRD 461
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 2524968378 491 GEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQQAHSVQE 533
Cdd:PRK13571 462 GTAYVQAGGGVVADSDPDYEDNEARNKAAAVLRAIAAAETLRA 504
|
|
| TrpE-arch |
TIGR01820 |
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of ... |
134-525 |
8.65e-110 |
|
anthranilate synthase component I, archaeal clade; This model represents an archaeal clade of anthranilate synthase component I enzymes. This enzyme is responsible for the first step of tryptophan biosynthesis from chorismate. The Sulfolobus enzyme has been reported to be part of a gene cluster for Trp biosynthesis [Amino acid biosynthesis, Aromatic amino acid family]
Pssm-ID: 273819 [Multi-domain] Cd Length: 435 Bit Score: 334.33 E-value: 8.65e-110
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 134 EPLRILQQQLMKANDTAQKHPFSVFLGGA---FAYDFVASY-EPLPQVEEGENDCPDYVFYLAETLLIIDHqaqtteLLG 209
Cdd:TIGR01820 58 DVVDKLRNAFPKLKGINIPGEDRRFKGGLvgyIAYDAVRDYwEGIVDLKRKAEDWPPAEFFIYPNTIVYDH------LEG 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 210 SVFGGKDHDKRYQAmsQRVGELAARCQLPaitpEPLPVDVSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSR--RFKM 287
Cdd:TIGR01820 132 KVYYVSTPEPEAEL--ERIVERAKRATDP----GEAGVSFEGESLSDREEFEEAVEEAKEYIFAGDIFQVVLSReyEYRL 205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 288 PCPePLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKDsnQVELYPIAGTRPRGKNADGsinldlDSRMELEL 367
Cdd:TIGR01820 206 DGD-PFELYYNLREINPSPYMFLLKFGDRYLVGSSPETLVRVEGR--TVETNPIAGTRPRGATPEE------DERLAKEL 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 368 RLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKV 447
Cdd:TIGR01820 277 LSDEKERAEHVMLVDLARNDVRKVSEPGSVKVPEFMYVEKYSHVQHIESTVIGTLKKDYDAFDALRATFPAGTLSGAPKI 356
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2524968378 448 SAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAI 525
Cdd:TIGR01820 357 RAMEIIDELEKEPRGVYGGGVGYFSWNGDADFAIAIRTAEIDKDKLRIQAGAGIVADSIPEREFEETENKMKAVLKAI 434
|
|
| Chorismate_bind |
pfam00425 |
chorismate binding enzyme; This family includes the catalytic regions of the chorismate ... |
258-517 |
2.89e-105 |
|
chorismate binding enzyme; This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.
Pssm-ID: 425674 [Multi-domain] Cd Length: 255 Bit Score: 316.03 E-value: 2.89e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 258 DEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCP---EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALkyQKDSN 334
Cdd:pfam00425 1 EDYLAAVEKAKEAIRAGDLYKVVLSRRLTLPLAgdiDPLALYRRLRARNPAPYSFYFRTGDFTFLGASPERLL--SVDGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 335 QVELYPIAGTRPRGKNADgsinldLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHL 414
Cdd:pfam00425 79 RIITEPIAGTRPRGKDPA------EDEALAAELLADPKERAEHLMVVDLIRNDLGRVCVPGSVKVPELPEVERYGTVQHL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 415 VSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAI 494
Cdd:pfam00425 153 VSTISGRLKPGLSLLDLLKALFPTGAVTGAPKKRAMEIIRELEPFPRGLYAGAVGYLDPDGDADFAVAIRTALVDNGRAR 232
|
250 260
....*....|....*....|...
gi 2524968378 495 VQAGAGVVHDSNPDSEVAETESK 517
Cdd:pfam00425 233 LYAGAGIVADSDPEAEWEETEAK 255
|
|
| PabB-clade2 |
TIGR01824 |
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely ... |
161-521 |
6.53e-92 |
|
aminodeoxychorismate synthase, component I, clade 2; This clade of sequences is more closely related to TrpE (anthranilate synthase, TIGR00564/TIGR01820/TIGR00565) than to the better characterized group of PabB enzymes (TIGR00553/TIGR01823). This clade includes one characterized enzyme from Lactococcus and the conserved function across the clade is supported by these pieces of evidence: 1) all genomes with a member in this clade also have a separate TrpE gene, 2) none of these genomes contain an aparrent PabB from any of the other PabB clades, 3) none of these sequences are found in a region of the genome in association with other Trp biosynthesis genes, 4) all of these genomes aparrently contain most if not all of the steps of the folate biosynthetic pathway (for which PABA is a precursor). Many of the sequences hit by this model are annotated as TrpE enzymes, however, we believe that all members of this clade are, in fact, PabB. The sequences from Bacillus halodurans and subtilus which score below the trusted cutoff for this model are also likely to be PabB enzymes, but are too closely related to TrpE to be separated at this time.
Pssm-ID: 130883 Cd Length: 355 Bit Score: 285.51 E-value: 6.53e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 161 GAFAYDFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQtteLLGSVFGGKDHDKRYQAMSQRVGELAARCQLPAI 240
Cdd:TIGR01824 5 GWLAYDVARRLEGIPDLGTSDGGWPVAADFRYEAAVARDHQRQ---IVALATVPAETEGEFATSSDQLPAVAAATSLPSP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 241 TPEPLPVDVSVTATPSADEfaSIVTQLKKNIVAGDIFQVVPSRRFKMPCP---EPLAAYNQLKKNNPSPYMFFMSHPDFC 317
Cdd:TIGR01824 82 DVGPLPVDLEASIDRAAYE--TGVRRIKDYIRAGDVFQANLSRRLTAPIAadvDPLQLFLALRAPNPAPYAIYLEEPGVD 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 318 LFGASPESALKyqKDSNQVELYPIAGTRPRGKNadgsinLDLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSR 397
Cdd:TIGR01824 160 VASASPELFLA--REGRVVQTRPIAGTRPRGAT------LAEDGALAAELLQHDKDRAEHVMIVDLERNDLGRVCATGTV 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 398 YVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDM 477
Cdd:TIGR01824 232 RVPELCAVESYSHVHHLVSRVTGRLREGAGLADLIRALFPGGSITGAPKVRAMEIIDELEPQPRGPYTGSVGWIDADGNA 311
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 2524968378 478 DTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAV 521
Cdd:TIGR01824 312 DLNILIRTLEGGGAQLHFRTGAGIVADSDPAGEWDETEAKARAL 355
|
|
| PRK13566 |
PRK13566 |
anthranilate synthase component I; |
59-528 |
3.34e-80 |
|
anthranilate synthase component I;
Pssm-ID: 237429 [Multi-domain] Cd Length: 720 Bit Score: 265.63 E-value: 3.34e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 59 IDAALQLTCNEQQVTIQALTDNGNALLPWIQKKLESCATITALG-NGLVADFTLAAPSQgdvPVDEDSRLRQISNMEPLR 137
Cdd:PRK13566 65 VDPPLEITARGRTFTIEALNARGRVLLPFLADTLKALSEVVVLQsTANRIDGTIKEPDA---VFTEEERSRQPSVFTVLR 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 138 ILQQqLMKANDTAqkhpfsvFLG--GAFAYDFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGSVFGGK 215
Cdd:PRK13566 142 ALIA-LFASEEDP-------HLGlyGAFGYDLAFQFEPIEQKLPRPDDQRDLVLYLPDEILVVDHYAARAWVDRYEFAVG 213
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 216 DHDKRYQAmsqRVGELA--ARCQLPAITPEPLPvdvsvtatpsaDEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCPE-P 292
Cdd:PRK13566 214 GVSTEGLP---RETAPSpyKPTTARPGFADHAP-----------GEYAALVEKAKESFRRGDLFEVVPGQTFYEPCERsP 279
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 293 LAAYNQLKKNNPSPYMFFMS--HPDFcLFGASPESALKYqkDSNQVELYPIAGTRPRGKNADGsinldlDSRMELELRLD 370
Cdd:PRK13566 280 SEIFRRLKEINPSPYGFFINlgDGEY-LVGASPEMFVRV--EGRRVETCPISGTIKRGADAIG------DAEQIRKLLNS 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 371 QKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAA 450
Cdd:PRK13566 351 KKDESELTMCTDVDRNDKSRVCEPGSVKVIGRRQIEMYSRLIHTVDHVEGRLRPGFDALDAFLTHAWAVTVTGAPKLWAM 430
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2524968378 451 TLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQQA 528
Cdd:PRK13566 431 QFIEDHERSPRRWYGGAVGMVGFDGDMNTGLTLRTIRIKDGVAEVRVGATLLFDSDPEAEEAETELKASALLQALRGA 508
|
|
| PRK13574 |
PRK13574 |
anthranilate synthase component I; Provisional |
132-525 |
3.11e-79 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184155 [Multi-domain] Cd Length: 420 Bit Score: 254.74 E-value: 3.11e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 132 NMEPLRILQQQLMKANDTAQKHPFSVFLGGAFAYDFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQaqttelLGSV 211
Cdd:PRK13574 55 HDDPVNILNSYLKDLKLVDIPGLFKGGMIGYISYDAVRFWEKIRDLKPAAEDWPYAEFFIPDNIIIYDHN------EGKV 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 212 FGGKDHDKRYQAMSqrVGELAarcqlpaITPEplpvDVSVTATpsadEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCP- 290
Cdd:PRK13574 129 YVNGDLSSVGGCGD--MGEFK-------ISFY----DESLNKN----NYEKIVSESLEYIRSGYIFQVVLSRFYRYLFSg 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 291 EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKdsNQVELYPIAGTRPRGKNADGSINLdldsrmELELRLD 370
Cdd:PRK13574 192 DPLRIYYNLRRINPSPYMFYLKFDERYLIGSSPELLFRVQD--NIVETYPIAGTRPRGSDQEEDLKL------ELELMNS 263
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 371 QKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAA 450
Cdd:PRK13574 264 EKDKAEHLMLVDLARNDLGKVCVPGTVRVPELMYVEKYSHVQHIVSKVIGTLKKKYNALDVLKATFPAGTVSGAPKPMAM 343
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2524968378 451 TLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAI 525
Cdd:PRK13574 344 NIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKDLLRIQAGAGIVYDSNPESEYFETEHKLRALKTAI 418
|
|
| PRK05940 |
PRK05940 |
anthranilate synthase component I; |
134-531 |
1.80e-76 |
|
anthranilate synthase component I;
Pssm-ID: 235651 [Multi-domain] Cd Length: 463 Bit Score: 248.88 E-value: 1.80e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 134 EPLRILQQQLMKAND--TAQKH-PFSVFLGGAFAYDFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGS 210
Cdd:PRK05940 72 EILPFLRQLLARSLDpsALPEHlPFTGGWLGWLGYDLAWEIERLPHLNPDPLPFPVAYWYEPESFAILDHQEQILWLAAS 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 211 VFGGKDHDkryqamsqrvgelaaRCQLPAITPEP-LPVDVSVTATP-----SADEFASIVTQLKKNIVAGDIFQVVPSRR 284
Cdd:PRK05940 152 DPSQLDRL---------------EQQLEQPTPEPdLPLDLRTPPSSlifytTQQEYEAAVRQAKKYIQAGDIFQANLSLR 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 285 FKMPCP-EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQkdSNQVELYPIAGTRPRGKNadgsinLDLDSRM 363
Cdd:PRK05940 217 FQTTTSaDSWQIYRRLQQINPSPFASYWRTPWGDVVSCSPERLVQLQ--GNQAQTRPIAGTRPRGKT------PAEDQQL 288
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 364 ELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVG 443
Cdd:PRK05940 289 AEELLSNIKERAEHIMLVDLERNDLGRVCQWGSVEVDELLTIERYSHVIHLVSNVVGTLQPNRDAIDLIRALFPGGTITG 368
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 444 APKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFV---KNGEAIV--QAGAGVVHDSNPDSEVAETESKA 518
Cdd:PRK05940 369 CPKVRCMEIIEELEPVRRNLFYGSCGYLDQRGNLDLNILIRTLLYtplSRGLSTIwgQVGAGIVADSDPEKEWLESLQKA 448
|
410
....*....|...
gi 2524968378 519 KAVILAIQQAHSV 531
Cdd:PRK05940 449 KAQLAALNLVRSQ 461
|
|
| PLN02445 |
PLN02445 |
anthranilate synthase component I |
157-530 |
2.58e-76 |
|
anthranilate synthase component I
Pssm-ID: 215244 [Multi-domain] Cd Length: 523 Bit Score: 250.37 E-value: 2.58e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 157 VFLGG---AFAYDFVASYE----PLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGSVF--GGKDHDKRYQAMSQR 227
Cdd:PLN02445 117 VFCGGwvgYFSYDTVRYVEkkklPFSGAPEDDRNLPDIHLGLYDDVIVFDHVEKKAYVIHWVRldRYSSVEEAYEDGMKR 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 228 VGELAARCQlpAITPEPLP---VDVSVTATPSA--------DEFASIVTQLKKNIVAGDIFQVVPSRRF-KMPCPEPLAA 295
Cdd:PLN02445 197 LEALVSRLQ--DINPPKLSpgsVKLSTNQFGPSleksnmtsEEYKNAVLQAKEHILAGDIFQIVLSQRFeRRTFADPFEV 274
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 296 YNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKdsNQVELYPIAGTRPRGKNADGsinldlDSRMELELRLDQKELA 375
Cdd:PLN02445 275 YRALRIVNPSPYMIYLQARGCILVASSPEILTRVKK--NKIVNRPLAGTRRRGKTPEE------DKALEKDLLADEKQCA 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 376 EHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQ 455
Cdd:PLN02445 347 EHIMLVDLGRNDVGKVSKAGSVKVEKLMNIERYSHVMHISSTVTGELLDHLTSWDALRAALPVGTVSGAPKVRAMELIDE 426
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 456 VEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGE------------------AIVQAGAGVVHDSNPDSEVAETESK 517
Cdd:PLN02445 427 LEVTRRGPYSGGFGGVSFTGDMDIALALRTMVFPTAArydtmysykdtnsrrewvAHLQAGAGIVADSDPEDEYRECVNK 506
|
410
....*....|...
gi 2524968378 518 AKAVILAIQQAHS 530
Cdd:PLN02445 507 AAGLARAIDLAES 519
|
|
| PRK13572 |
PRK13572 |
anthranilate synthase component I; Provisional |
256-525 |
7.03e-75 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 237432 [Multi-domain] Cd Length: 435 Bit Score: 243.88 E-value: 7.03e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 256 SADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCP-EPLAAYNQLKKNNPSPYMFFMSHpDFCLFGASPESALKYQKdsN 334
Cdd:PRK13572 171 DREEFVEMVEKAKEYIYSGDVFQVVLSREYRLKTDlSPFQLYRNLREINPSPYMFLLEF-DKDVVGASPETMASVEN--N 247
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 335 QVELYPIAGTRPRGKNADGsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHL 414
Cdd:PRK13572 248 ILKINPIAGTAPRGKTEEE------DKKLAEALLSDEKERAEHVMLVDLARNDVRKVSKSGSVRLERFFDVVKYSHVQHI 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 415 VSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVkNGEAI 494
Cdd:PRK13572 322 ESEVVGELKEDSTMFDAIEAAFPAGTLTGAPKFRAMEIIDELEKSRRKVYGGAVGYFSNSGNADLAIAIRMAEI-DKVCR 400
|
250 260 270
....*....|....*....|....*....|.
gi 2524968378 495 VQAGAGVVHDSNPDSEVAETESKAKAVILAI 525
Cdd:PRK13572 401 VRAGAGIVADSVPEKEFYETERKMAAVLKAL 431
|
|
| PRK09070 |
PRK09070 |
aminodeoxychorismate synthase component I; |
92-528 |
7.26e-75 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236371 [Multi-domain] Cd Length: 447 Bit Score: 244.23 E-value: 7.26e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 92 LESCATITALGNglvADFTLAAPSQGdVPVDEDSRLRQISNMEPLRIL---QQQLMKANDTAQKHPFSvflGGAF---AY 165
Cdd:PRK09070 28 LESSASGTAQGR---WDVLLLAQGKC-LRLDPDGVTRQLLEGDFLDALdaaWQAERVPHDGESSLPFR---GGWAvllDY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 166 DFVASYEPLPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGSVfggkDHDKRYQAMsqrVGELAARCQLPaitpePL 245
Cdd:PRK09070 101 ELAGQVEPILKLPMRTDGLPLALALRAPAAVLRDRHSGRCVLVAEP----GREHLLDQI---EADLAACAALP-----PL 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 246 PVDVSVTATPSADE--FASIVTQLKKNIVAGDIFQVVPSRRFKM---PCPEPLAAYNQLKKNNPSPYMFFMSHPDFCLFG 320
Cdd:PRK09070 169 PVWLAPQAVEEDPPerFTDGVERVLDYIRAGDVFQVNLSRAWQAqfaNAVDPAALYARLRAANPAPFSGLFVAAGRAIVS 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 321 ASPESALKYQkdSNQVELYPIAGTRPRGKNADgsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVA 400
Cdd:PRK09070 249 SSPERLVSVQ--GGVVQTRPIAGTRPRFAGDD-------DAALIRELVGHPKERAEHVMLIDLERNDLGRICAPGSVEVD 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 401 DLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTC 480
Cdd:PRK09070 320 ELMTVESYAHVHHIVSNVRGRLRDGVTPGEVIRAVFPGGTITGCPKVRCMQIIAELEQTPRGAYTGSFGYLNRDGDMDLN 399
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 2524968378 481 IVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQQA 528
Cdd:PRK09070 400 ILIRTAEVQGNQVRFRTGAGIVVDSDPERELDETRAKARGLLRALEQA 447
|
|
| PRK13567 |
PRK13567 |
anthranilate synthase component I; Provisional |
154-522 |
7.13e-63 |
|
anthranilate synthase component I; Provisional
Pssm-ID: 184148 [Multi-domain] Cd Length: 468 Bit Score: 213.47 E-value: 7.13e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 154 PF-SVFLGGAfAYDFVASYEP-LPQVEEGENDCPDYVFYLAETLLIIDHQAQTTELLGSVFGGKDHDKRYQAMSQRVGEL 231
Cdd:PRK13567 96 PFiSGYVGTC-SFDLVRHEFPkLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATNQFSNSTKSDLENRVNKSIED 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 232 AARCQLPAITPEPLPVDVSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSR--RFKMPCPEPLAA-----YNQLKKNNP 304
Cdd:PRK13567 175 LTKIQPFMPTQDFDFKTKEIQSNISEERFIEMIQYFKEKITEGDMFQVVPSRiyKYAHHASQHLNQlsfqlYQNLKRQNP 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 305 SPYMFFMSHPDFCLFGASPESALKYQKdsNQVELYPIAGTRPRGKNadgsinLDLDSRMELELRLDQKELAEHLMLVDLA 384
Cdd:PRK13567 255 SPYMYYLNIDQPYIVGSSPESFVSVKD--QIVTTNPIAGTIQRGET------TQIDNENMKQLLNDPKECSEHRMLVDLG 326
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 385 RNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSY 464
Cdd:PRK13567 327 RNDIHRVSKIGTSKITKLMVIEKYEHVMHIVSEVTGKINQNLSPMTVIANLLPTGTVSGAPKLRAIERIYEQYPHKRGVY 406
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 2524968378 465 GGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVI 522
Cdd:PRK13567 407 SGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPEKELNETKLKAKSLL 464
|
|
| pabB |
PRK15465 |
aminodeoxychorismate synthase component 1; |
105-522 |
2.29e-58 |
|
aminodeoxychorismate synthase component 1;
Pssm-ID: 185362 [Multi-domain] Cd Length: 453 Bit Score: 200.92 E-value: 2.29e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 105 LVADFTLAAPSQGDVPVDEDSRLRQISNMEPLRILQQQLMKANDTAQKHPFSVFLGGA---FAYDFVASYEPLPQVEEGE 181
Cdd:PRK15465 49 VVADPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPFQGGAlglFGYDLGRRFESLPEIAEQD 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 182 NDCPDYVFYLAETLLIIDHQAQTTELLGSvfggKDHDKRYQAMSQRvgelaarcQLPaiTPEPLPVDVSVTATPSADEFA 261
Cdd:PRK15465 129 IVLPDMAVGIYDWALIVDHQRQTVSLLSH----NDVNARRAWLESQ--------QFS--PQEDFTLTSDWQSNMTREQYG 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 262 SIVTQLKKNIVAGDIFQVVPSRRFKMPCP-EPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALkyQKDSNQVELYP 340
Cdd:PRK15465 195 EKFRQVQEYLHSGDCYQVNLAQRFHATYSgDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFI--LCDNSEIQTRP 272
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 341 IAGTRPRGKNADGsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVA 420
Cdd:PRK15465 273 IKGTLPRLPDPQE------DSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPFPAVHHLVSTITA 346
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 421 KLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAG 500
Cdd:PRK15465 347 RLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGG 426
|
410 420
....*....|....*....|..
gi 2524968378 501 VVHDSNPDSEVAETESKAKAVI 522
Cdd:PRK15465 427 IVADSQEEAEYQETFDKVNRIL 448
|
|
| PRK07508 |
PRK07508 |
aminodeoxychorismate synthase component I; |
237-519 |
7.30e-49 |
|
aminodeoxychorismate synthase component I;
Pssm-ID: 236035 [Multi-domain] Cd Length: 378 Bit Score: 173.27 E-value: 7.30e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 237 LPAITPEPLPVDVSVTATPSADEFASIVTQLKKNIVAGDIFQVvpsrRFKMPCP-----EPLAAYNQLKKNNPSPYMFFM 311
Cdd:PRK07508 91 APARPSENAARLRDPVARWDFADYAQRFERLHRHIRAGDCYQA----NLTFPLDarwggDPLALFWALAARQPVGYGALV 166
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 312 SHPDFCLFGASPEsaLKYQKDSN-QVELYPIAGTRPRGKNADGsinldlDSRMELELRLDQKELAEHLMLVDLARNDLAR 390
Cdd:PRK07508 167 DLGGPVILSRSPE--LFFRVDGEgWIETHPMKGTAPRGATPAE------DARLRAALLNDEKNQAENRMIVDLLRNDISR 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 391 ISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDC---DALHAYRACmnmGTLVGAPKVSAATLIRQVEKQRRGSYGGA 467
Cdd:PRK07508 239 ISEVGSLDVPELFDIETYPTVHQMVSRVRARLLPGLglaDIFAALFPC---GSITGAPKIRAMEILRELEPGPRDLYCGA 315
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 2524968378 468 VGYLAGNGDMDTCIVIRS-AFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAK 519
Cdd:PRK07508 316 IGWIAPDGRMRFNVAIRTlSLFPGGRAVFNVGGGIVFDSTAEAEYEECLLKAR 368
|
|
| MenF |
COG1169 |
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites ... |
250-526 |
2.54e-46 |
|
Isochorismate synthase EntC [Coenzyme transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; Isochorismate synthase EntC is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440783 [Multi-domain] Cd Length: 353 Bit Score: 165.71 E-value: 2.54e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 250 SVTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCPEPLAAY---NQLKKNNPSPYMFFMSHPDF-CLFGASPEs 325
Cdd:COG1169 81 SRRGVPDPAEWREAVAQALEAIRAGELDKVVLARALDLTLDEPIDPRallARLRRRNPDCYTFAVELGAGdGFVGASPE- 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 326 aLKYQKDSNQVELYPIAGTRPRGKNADgsinldLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSryVADLLQV 405
Cdd:COG1169 160 -RLVRRRGGQLTTEALAGTAPRGADPE------EDAALAAALLASEKDRREHALVVDSIREALAPLCSSLD--VPEEPEL 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 406 DRYSQVMHLVSRVVAKLRDDCDALHAYRA-------CmnmgtlvGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMD 478
Cdd:COG1169 231 LRLRNVQHLATPITGTLDPGVSALDLAAAlhptpavG-------GTPREAALALIRELEPFDRGWYAGPVGWVDADGDGE 303
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 2524968378 479 TCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVILAIQ 526
Cdd:COG1169 304 FAVAIRSALIDGNRARLFAGAGIVAGSDPEAEWAETEAKLRTMLRALG 351
|
|
| PLN02889 |
PLN02889 |
oxo-acid-lyase/anthranilate synthase |
185-522 |
8.05e-45 |
|
oxo-acid-lyase/anthranilate synthase
Pssm-ID: 215481 [Multi-domain] Cd Length: 918 Bit Score: 170.03 E-value: 8.05e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 185 PDYVFYLAETLLIIDHQAQTTELLGSVFGG-------KDHDKRY---QAMSQRVGELAArcqLPAITPEPlpVDVSVTAT 254
Cdd:PLN02889 566 PDACFFFADNVVVIDHHYDDVYILSLHEGStattqwlDDTEQKLlglKASATRKLEVQT---SPTATFSP--SKAGFLAD 640
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 255 PSADEFASIVTQLKKNIVAGDIFQV--VPSRRFKMPCPEPLAAYNQLKKNNPSPYMFFM--SHPDFCLFGASPESALKYQ 330
Cdd:PLN02889 641 KSREQYIKDVQKCLKYIKDGESYELclTTQMRKRIGEIDSLGLYLHLREKNPAPYAAWLnfSNENLCICSSSPERFLKLD 720
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 331 KDSnQVELYPIAGTRPRGknadgsINLDLDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQ 410
Cdd:PLN02889 721 RNG-MLEAKPIKGTIARG------STPEEDEQLKLQLQYSEKDQAENLMIVDLLRNDLGRVCEPGSVHVPNLMDVESYTT 793
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 411 VMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKN 490
Cdd:PLN02889 794 VHTMVSTIRGKKRSNMSPVDCVRAAFPGGSMTGAPKLRSMELLDSLESSSRGIYSGSIGFFSYNQTFDLNIVIRTVVIHE 873
|
330 340 350
....*....|....*....|....*....|....*.
gi 2524968378 491 GEAIVQAGAGVVHDSNPDSEVAE----TESKAKAVI 522
Cdd:PLN02889 874 GEASIGAGGAIVALSNPEDEYEEmilkTRAPANAVI 909
|
|
| PRK06404 |
PRK06404 |
anthranilate synthase component I; Reviewed |
264-522 |
5.01e-44 |
|
anthranilate synthase component I; Reviewed
Pssm-ID: 102361 [Multi-domain] Cd Length: 351 Bit Score: 159.65 E-value: 5.01e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 264 VTQLKKNIVAGDIFQVVPSRRFKmPCPEPLAAYNQLKKNNPSPYMFFMSHPDFCLFGASPESAlkYQKDSNQVELYPIAG 343
Cdd:PRK06404 111 IKELIELIRAGEVLQVVISREFE-ANIDFKEKLSEFINNDRSRYVFYYRFGKYRVVGSSPENV--FTVNGNIINVDPIAG 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 344 TRPrgknadgsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLr 423
Cdd:PRK06404 188 TYD-------------DKILSNELLNSEKDKLEHRMLLDLARNDLSKFADIGTLNVDKVMKIEEFSSVKHLVSQVTAKF- 253
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 424 DDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVGyLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVH 503
Cdd:PRK06404 254 SNASYRDILASMFPAGTVSGSPKERAIEIINKYEETPRGPYGGAIG-IISKGYTDMALVIRTAYSHGNGFRVRAGAGIVK 332
|
250
....*....|....*....
gi 2524968378 504 DSNPDSEVAETESKAKAVI 522
Cdd:PRK06404 333 DSDPEDEVNEIYSKARSVM 351
|
|
| PRK05877 |
PRK05877 |
aminodeoxychorismate synthase component I; Provisional |
229-522 |
2.01e-35 |
|
aminodeoxychorismate synthase component I; Provisional
Pssm-ID: 235634 [Multi-domain] Cd Length: 405 Bit Score: 137.14 E-value: 2.01e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 229 GELAARCQLPaitPEPLPVDVSvtaTPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCP-EPLAAYNQLKKNNPSPY 307
Cdd:PRK05877 119 SALATTRARP---APPCRIDWT---PPDRAAHRDGVLACLEAIAAGEVYQACVCTQFTGTVTgSPLDFFADGVARTAPAR 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 308 MFFMSHPDFCLFGASPESALKYQKDSnqVELYPIAGTRPRGKNADgsinldldsrmelELRLDQKELAEHLMLVDLARND 387
Cdd:PRK05877 193 AAYLAGDWGAVASLSPELFLRRRGSV--VTSSPIKGTLPLDADPS-------------ALRASAKDVAENIMIVDLVRND 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 388 LARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGA 467
Cdd:PRK05877 258 LGRVARTGTVTVPELLVVRPAPGVWHLVSTVSAQVPDELPMSDLLDATFPPASVTGTPKLRARELISQWEPVRRGIYCGT 337
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2524968378 468 VGYLAGNGDMDTCIVIRSA-FVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAVI 522
Cdd:PRK05877 338 VGLASPVAGCELNVAIRTVeFDADGNAVLGVGGGITADSDPDAEWQECLHKAAPIV 393
|
|
| PRK07912 |
PRK07912 |
salicylate synthase; |
210-517 |
3.64e-29 |
|
salicylate synthase;
Pssm-ID: 169151 [Multi-domain] Cd Length: 449 Bit Score: 120.28 E-value: 3.64e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 210 SVFGGKDHDKryqamsQRVGELAARCQLPAitPEPLPVDVSVTATPSADEFASIVTQlkknIVAGDIFQVVPSRRFKMPC 289
Cdd:PRK07912 148 RLFGAGIRHR------EAIDRLLATGVREV--PQSRSVDVSDDPSGYRDRVAVAVAE----IAAGRYHKVILSRCVEVPF 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 290 PEPL-AAYNQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKDSnQVELYPIAGTRPRGKNADgsinLDLDSRMELELr 368
Cdd:PRK07912 216 AVDFpATYRLGRRHNTPVRSFLLRLGGIRALGYSPELVTAVRADG-VVITEPLAGTRAFGRGAA----IDRLARDDLES- 289
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 369 lDQKELAEHLMLVDLARNDLARISETGSRYVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVS 448
Cdd:PRK07912 290 -NSKEIVEHAISVRSSLAEITEIAEPGSAAVIDFMTVRERGSVQHLGSTVRGRLDASSDRMDALEALFPAVTASGIPKAA 368
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2524968378 449 AATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESK 517
Cdd:PRK07912 369 GVDAIFRLDEAPRGLYSGAVVMLSADGGLDAALTLRAAYQVGGRTWLRAGAGIIEESEPEREFEETCEK 437
|
|
| PRK07054 |
PRK07054 |
isochorismate synthase; |
218-528 |
3.58e-27 |
|
isochorismate synthase;
Pssm-ID: 235920 [Multi-domain] Cd Length: 475 Bit Score: 114.48 E-value: 3.58e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 218 DKRYQAMSQRVGE-------LAARC-----QLPAITP-EPLPVDVSV-TATPSADEFASIVTQLKKNIVAGDIFQVVPSR 283
Cdd:PRK07054 141 GEAYWAVCQHLVAahddpaaLAGACcarieRLARPAPaADDDAPRLLrASALQAREWQHEVRRAVDAIRGGAFGKVVLAR 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 284 RFKMPCPEPLAAY---NQLKKNNPSPYMFFMSHPDFCLFGASPESALKYQKDsnQVELYPIAGTRPRGKNADGsinldlD 360
Cdd:PRK07054 221 DVLQQYARPVAIGpllRRLRLRDPHAHLFAFRRGNACFLGATPERLVRVAAG--DLHTHALAGTIARGADPAE------D 292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 361 SRMELELRLDQKELAEHLMLVDLARNDLARISETGSryVADLLQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGT 440
Cdd:PRK07054 293 ARLGAALMASAKDRLEHALVVDAIRAALAPLSRALD--IPDQPSLHRLPRLQHLSTPIRATLAPDATLLQVVAALHPTPA 370
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 441 LVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKA 520
Cdd:PRK07054 371 VGGHPRAAALDYIRAHEGFDRGWYAAPIGWLDAHGNGDFAVALRSALITGGACRLFAGCGIVADSEPASEYRETCLKLSG 450
|
....*...
gi 2524968378 521 VILAIQQA 528
Cdd:PRK07054 451 MREALRAR 458
|
|
| PRK06772 |
PRK06772 |
salicylate synthase; |
244-521 |
3.29e-25 |
|
salicylate synthase;
Pssm-ID: 102546 [Multi-domain] Cd Length: 434 Bit Score: 108.28 E-value: 3.29e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 244 PLPVDVSVTATPSADEFASIVTQLKKnivaGDIFQVVPSRRFKMPCPEPLAAYNQLKKNNPSPYMFFMSHPD-FCLFGAS 322
Cdd:PRK06772 163 PLAVDTALNGEAYKQQVARAVAEIRR----GEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEgREALGFS 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 323 PESALKYQkdSNQVELYPIAGTRPRGKNADGsinldlDSRMELELRLDQKELAEHLMLVDLARNDLARISETGSRYVADL 402
Cdd:PRK06772 239 PELVMSVT--GNKVVTEPLAGTRDRMGNPEH------NKAKEAELLHDSKEVLEHILSVKEAIAELEAVCQPGSVVVEDL 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 403 LQVDRYSQVMHLVSRVVAKLRDDCDALHAYRACMNMGTLVGAPKVSAATLIRQVEKQRRGSYGGAVgYLAGNGDMDTCIV 482
Cdd:PRK06772 311 MSVRQRGSVQHLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAI-LLLDDTRFDAALV 389
|
250 260 270
....*....|....*....|....*....|....*....
gi 2524968378 483 IRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAV 521
Cdd:PRK06772 390 LRSVFQDSQRCWIQAGAGIIAQSTPERELTETREKLASI 428
|
|
| PRK06923 |
PRK06923 |
isochorismate synthase DhbC; Validated |
225-525 |
8.85e-24 |
|
isochorismate synthase DhbC; Validated
Pssm-ID: 235886 [Multi-domain] Cd Length: 399 Bit Score: 103.66 E-value: 8.85e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 225 SQRVGELAARCQLPAITPEPLPVDVsvTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCPEPLAAyNQLKKN-- 302
Cdd:PRK06923 91 SRISERLQLDTTNHLEINRNLTFEM--TPVPDPEVYMNGVKQGIAKIQDGDLKKIVLSRSLDVKSSEKIDK-QKLLREla 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 303 --NPSPYMFFMSHPD------FCLFGASPEsaLKYQKDSNQVELYPIAGTRPRgknadgSINLDLDSRMELELRLDQKEL 374
Cdd:PRK06923 168 ehNKHGYTFAVNLPKdenensKTLIGASPE--LLVSRHGMQVISNPLAGSRPR------SDDPVEDKRRAEELLSSPKDL 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 375 AEHLMLVDLARNDLarisetgsRYVADLLQVDR-----YSQVM-HLVSRVVAKLRDD-------CDALHAYRAcmnmgtL 441
Cdd:PRK06923 240 HEHAVVVEAVAAAL--------RPYCHTLHVPEkpsviHTEAMwHLSTEVKGELKDPntsslelAIALHPTPA------V 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 442 VGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKAKAV 521
Cdd:PRK06923 306 CGTPTEEAREAIQQIEPFDREFFTGMLGWSDLNGDGEWIVTIRCAEVEENTLRLYAGAGVVAESKPEDELAETSAKFQTM 385
|
....
gi 2524968378 522 ILAI 525
Cdd:PRK06923 386 LKAM 389
|
|
| PLN02786 |
PLN02786 |
isochorismate synthase |
275-518 |
2.61e-21 |
|
isochorismate synthase
Pssm-ID: 178383 [Multi-domain] Cd Length: 533 Bit Score: 97.16 E-value: 2.61e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 275 DIFQVVPSRRFKM---PCPEPLAAYNQLKKNNPSPYMFFMSHPDFCLF-GASPESAlkYQKDSNQVELYPIAGTRPRGkn 350
Cdd:PLN02786 279 PLKKVVLARSSRIitdTDIDPIAWLACLQVEGQNAYQFCLQPPDAPAFiGNTPEQL--FHRKGLGVCSEALAATRPRG-- 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 351 adGSINLDLDsrMELELRLDQKELAEHLMLVDLARNDLARISETgsRYVADLLQVDRYSQVMHLVSRVVAKLRDDCD--- 427
Cdd:PLN02786 355 --GSSARDLQ--IELDLLTSPKDDLEFSIVRENIREKLEAICDR--VVVEPHKAIRKLARVQHLYAQLAGRLRSEDDefd 428
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 428 ---ALHAYRAcmnmgtLVGAPKVSAATLIRQVEKQRRGSYGGAVGYLAGnGDMDTCIVIRSAFVKNG-EAIVQAGAGVVH 503
Cdd:PLN02786 429 ilaALHPTPA------VCGHPTEEARLLIAETESFDRGMYAGPVGWFGG-GESEFAVGIRSALVEKGlGALIYAGTGIVE 501
|
250
....*....|....*
gi 2524968378 504 DSNPDSEVAETESKA 518
Cdd:PLN02786 502 GSNPSSEWNELELKI 516
|
|
| PRK07093 |
PRK07093 |
para-aminobenzoate synthase component I; Validated |
313-517 |
1.53e-19 |
|
para-aminobenzoate synthase component I; Validated
Pssm-ID: 235932 [Multi-domain] Cd Length: 323 Bit Score: 89.54 E-value: 1.53e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 313 HPDFCLFgaSPESALKYQKdsNQVELYPIAGTrprgknadgsINLDLDSRMELELRlDQKELAEHLMLVDLARNDLARIS 392
Cdd:PRK07093 125 KDQFVCF--SPEPFVRIED--NKISTYPMKGT----------IDASLPNAEEKLLN-DEKEFAEHATIVDLLRNDLSMVA 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 393 E----TGSRYV-------ADLLQVDrysqvmhlvSRVVAKLRDDcdalhaYRAcmNMGTLV----------GAPKVSAAT 451
Cdd:PRK07093 190 KnvrvTRFRYIdkiktnkGEILQTS---------SEISGTLPEN------WQE--NIGDILakllpagsitGAPKEKTVE 252
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2524968378 452 LIRQVEKQRRGSYGGAVGYLAGNgDMDTCIVIRsaFVK--NGEAIVQAGAGVVHDSNPDSEVAETESK 517
Cdd:PRK07093 253 IIEQAEGYERGFYTGVFGYFDGE-SLDSAVMIR--FIEqeNDGLYFKSGGGITIDSDLKDEYNELIQK 317
|
|
| PRK15016 |
PRK15016 |
isochorismate synthase EntC; Provisional |
219-517 |
1.42e-12 |
|
isochorismate synthase EntC; Provisional
Pssm-ID: 184977 [Multi-domain] Cd Length: 391 Bit Score: 69.52 E-value: 1.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 219 KRYQAMSQRVGELAARcqlpAITPEPLPVDVSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPC---PEPLAA 295
Cdd:PRK15016 92 ESWQSFSRQEKQRSAR----RFTRSQSLNVVERQAIPEQTTFEAMVARAAALTATPQVDKVVLSRLIDITTdaaIDSGAL 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 296 YNQLKKNNPSPYMFFMSHPD-FCLFGASPESALKyqKDSNQVELYPIAGTRPRGKNADgsinldLDSRMELELRLDQKEL 374
Cdd:PRK15016 168 LERLIAQNPVSYNFHVPLADgGVLLGASPELLLR--KDGERFSSLPLAGSARRQPDEV------LDREAGNRLLASEKDR 239
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 375 AEHLMLVDLARNDLARISETgsryvadlLQVDRYSQVM------HLVSRVVAKLRDDCDALHAyrACMNMGT--LVGAPK 446
Cdd:PRK15016 240 HEHELVTQAMKEVLRERSSE--------LHVPSSPQLIttptlwHLATPFEGKANAQENALTL--ACLLHPTpaLSGFPH 309
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2524968378 447 VSAATLIRQVEKQRRGSYGGAVGYLAGNGDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESK 517
Cdd:PRK15016 310 QAAKQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVK 380
|
|
| Anth_synt_I_N |
pfam04715 |
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) ... |
117-207 |
3.10e-10 |
|
Anthranilate synthase component I, N terminal region; Anthranilate synthase (EC:4.1.3.27) catalyzes the first step in the biosynthesis of tryptophan. Component I catalyzes the formation of anthranilate using ammonia and chorismate. The catalytic site lies in the adjacent region, described in the chorismate binding enzyme family (pfam00425). This region is involved in feedback inhibition by tryptophan. This family also contains a region of Para-aminobenzoate synthase component I (EC 4.1.3.-).
Pssm-ID: 428082 [Multi-domain] Cd Length: 140 Bit Score: 58.48 E-value: 3.10e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 117 GDVPVDEDSRLRQISNMEPLRILQQQLMKANDTAQKH---PFSVFLGGAFAYDFVASYEPLPQVEEGENDCPDYVFYLAE 193
Cdd:pfam04715 47 GEVSVSGPDGQELEQEDGPLDALRALLARFRIEDSPPtlpPFSGGLVGYLGYDLVRYIEKLPRTAPDDLNLPDARLILYE 126
|
90
....*....|....
gi 2524968378 194 TLLIIDHQAQTTEL 207
Cdd:pfam04715 127 DLIVFDHQENKLYL 140
|
|
| PRK15012 |
PRK15012 |
menaquinone-specific isochorismate synthase; Provisional |
236-518 |
7.29e-10 |
|
menaquinone-specific isochorismate synthase; Provisional
Pssm-ID: 184974 [Multi-domain] Cd Length: 431 Bit Score: 61.01 E-value: 7.29e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 236 QLPAITPEP---LPVdVSVTATPSADEFASIVTQLKKNIVAGDIFQVVPSRRFKMPCPEPLAAYNQL---KKNNPSPYMF 309
Cdd:PRK15012 146 TLVSIKPLPglhLTT-TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMaasRRLNLNCYHF 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 310 FMS-HPDFCLFGASPESALKYQKDSNQVElyPIAGTRprGKNADgsinlDLDSRMELE-LRLDQKELAEHLMLVDLARND 387
Cdd:PRK15012 225 YMAfDAENAFLGSSPERLWRRRDKALRTE--ALAGTV--ANHPD-----DKQAQQLGEwLMADDKNQRENMLVVEDICQR 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2524968378 388 LARISETgsryvADLL--QVDRYSQVMHLVSRVVAKLR--DDCDALHAYRAcmnMGTLVGAPKVSAATLIRQVEKQRRGS 463
Cdd:PRK15012 296 LQADTQT-----LDVLppQVLRLRKVQHLRRCIWTSLNkaDDVICLHQLQP---TAAVAGLPRDLARQFIARHEPFTREW 367
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 2524968378 464 YGGAVGYLAGNgDMDTCIVIRSAFVKNGEAIVQAGAGVVHDSNPDSEVAETESKA 518
Cdd:PRK15012 368 YAGSAGYLSLQ-QSEFCVSLRSAKVSGNVVRLYAGAGIVRGSDPEQEWQEIDNKA 421
|
|
| |
