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Conserved domains on  [gi|2507251447|ref|WP_282981637|]
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hypothetical protein, partial [Serratia sp. Se-RSmG]

Protein Classification

type II secretion system F family protein( domain architecture ID 10009000)

type II secretion system (T2SS) F family protein may play a role in nonspecific adherence to surfaces; similar to Aggregatibacter actinomycetemcomitans TadB, which is required for tight adherence to surfaces

Gene Ontology:  GO:0016020
PubMed:  18055598|14600218

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TadB COG4965
Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, ...
 67-156 4.59e-10

Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


:

Pssm-ID: 443991 [Multi-domain]  Cd Length: 214  Bit Score: 55.58  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2507251447  67 LTFSASSFAYVFGTVILVAISFTALYGIYQSRFSDYFEAQFPYALRLISRNLAVGQTIYAAIDAAAENLSDIMKREFTRI 146
Cdd:COG4965     6 LALLLTGLLLALLGALLGLLLPRLLLRRRAKRRRKKFEEQLPDALDLLARALRAGLSLPQALEAVAREAPEPLREEFRRI 85

                          90
                  ....*....|
gi 2507251447 147 SFQLKNGVSF 156
Cdd:COG4965    86 VRELRLGVDL 95
 
Name Accession Description Interval E-value
TadB COG4965
Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, ...
 67-156 4.59e-10

Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443991 [Multi-domain]  Cd Length: 214  Bit Score: 55.58  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2507251447  67 LTFSASSFAYVFGTVILVAISFTALYGIYQSRFSDYFEAQFPYALRLISRNLAVGQTIYAAIDAAAENLSDIMKREFTRI 146
Cdd:COG4965     6 LALLLTGLLLALLGALLGLLLPRLLLRRRAKRRRKKFEEQLPDALDLLARALRAGLSLPQALEAVAREAPEPLREEFRRI 85

                          90
                  ....*....|
gi 2507251447 147 SFQLKNGVSF 156
Cdd:COG4965    86 VRELRLGVDL 95
T2SSF pfam00482
Type II secretion system (T2SS), protein F; The original family covered both the regions found ...
 110-156 4.52e-03

Type II secretion system (T2SS), protein F; The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (archaeal FlaJ family) to be merged with it. Proteins with this domain in form a platform for the machiney of the Type II secretion system, as well as the Type 4 pili and the archaeal flagella. This domain seems to show some similarity to PF00664 but this may just be due to similarities in the TM helices (personal obs: C Yeats).


Pssm-ID: 425708 [Multi-domain]  Cd Length: 119  Bit Score: 35.00  E-value: 4.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2507251447 110 ALRLISRNLAVGQTIYAAIDAAAENLSDI-MKREFTRISFQLKNGVSF 156
Cdd:pfam00482   1 FLRQLATLLRAGLPLVEALEILAEEAENGpLREELRRIAERVREGGSL 48
 
Name Accession Description Interval E-value
TadB COG4965
Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, ...
 67-156 4.59e-10

Flp pilus assembly protein TadB [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 443991 [Multi-domain]  Cd Length: 214  Bit Score: 55.58  E-value: 4.59e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2507251447  67 LTFSASSFAYVFGTVILVAISFTALYGIYQSRFSDYFEAQFPYALRLISRNLAVGQTIYAAIDAAAENLSDIMKREFTRI 146
Cdd:COG4965     6 LALLLTGLLLALLGALLGLLLPRLLLRRRAKRRRKKFEEQLPDALDLLARALRAGLSLPQALEAVAREAPEPLREEFRRI 85

                          90
                  ....*....|
gi 2507251447 147 SFQLKNGVSF 156
Cdd:COG4965    86 VRELRLGVDL 95
T2SSF pfam00482
Type II secretion system (T2SS), protein F; The original family covered both the regions found ...
 110-156 4.52e-03

Type II secretion system (T2SS), protein F; The original family covered both the regions found by the current model. The splitting of the family has allowed the related FlaJ_arch (archaeal FlaJ family) to be merged with it. Proteins with this domain in form a platform for the machiney of the Type II secretion system, as well as the Type 4 pili and the archaeal flagella. This domain seems to show some similarity to PF00664 but this may just be due to similarities in the TM helices (personal obs: C Yeats).


Pssm-ID: 425708 [Multi-domain]  Cd Length: 119  Bit Score: 35.00  E-value: 4.52e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 2507251447 110 ALRLISRNLAVGQTIYAAIDAAAENLSDI-MKREFTRISFQLKNGVSF 156
Cdd:pfam00482   1 FLRQLATLLRAGLPLVEALEILAEEAENGpLREELRRIAERVREGGSL 48
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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