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Conserved domains on  [gi|2502262303|ref|WP_281665271|]
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VOC family protein [Paraburkholderia fungorum]

Protein Classification

VOC family protein( domain architecture ID 10001243)

vicinal oxygen chelate (VOC) family protein uses a metal center to coordinate a substrate, intermediate, or transition state through vicinal oxygen atoms

CATH:  3.10.180.10
Gene Ontology:  GO:0046872|GO:0003824
PubMed:  21820381|11076500

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GloA COG0346
Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary ...
 8-115 1.74e-12

Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary metabolites biosynthesis, transport and catabolism];


:

Pssm-ID: 440115 [Multi-domain]  Cd Length: 125  Bit Score: 59.62  E-value: 1.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMT--MREVDGTVDEPRQYWTLGG---LQFIHNPKHDAPE--GRLGHLGVMCEDMEAA 80
Cdd:COG0346     3 LHHVTLRVSDLEASLAFYTDVLGLElvKRTDFGDGGFGHAFLRLGDgteLELFEAPGAAPAPggGGLHHLAFRVDDLDAA 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2502262303  81 LAAAQKYDVS------EMPQGRNWLRL--PDGLAIELIQARPA 115
Cdd:COG0346    83 YARLRAAGVEiegeprDRAYGYRSAYFrdPDGNLIELVEPPPG 125
 
Name Accession Description Interval E-value
GloA COG0346
Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary ...
 8-115 1.74e-12

Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440115 [Multi-domain]  Cd Length: 125  Bit Score: 59.62  E-value: 1.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMT--MREVDGTVDEPRQYWTLGG---LQFIHNPKHDAPE--GRLGHLGVMCEDMEAA 80
Cdd:COG0346     3 LHHVTLRVSDLEASLAFYTDVLGLElvKRTDFGDGGFGHAFLRLGDgteLELFEAPGAAPAPggGGLHHLAFRVDDLDAA 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2502262303  81 LAAAQKYDVS------EMPQGRNWLRL--PDGLAIELIQARPA 115
Cdd:COG0346    83 YARLRAAGVEiegeprDRAYGYRSAYFrdPDGNLIELVEPPPG 125
Glyoxalase pfam00903
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;
8-109 3.90e-06

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;


Pssm-ID: 395724 [Multi-domain]  Cd Length: 121  Bit Score: 42.82  E-value: 3.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMTM--REVDGTVDEPRQYWTLGG-----LQFIHNPKHDAPEGRLGHLGVMC---EDM 77
Cdd:pfam00903   2 IDHVALRVGDLEKSLDFYTDVLGFKLveETDAGEEGGLRSAFFLAGgrvleLLLNETPPPAAAGFGGHHIAFIAfsvDDV 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2502262303  78 EAALAAAQKYDVSEMP--------QGRNWLRLPDGLAIEL 109
Cdd:pfam00903  82 DAAYDRLKAAGVEIVRepgrhgwgGRYSYFRDPDGNLIEL 121
VOC_like cd07245
uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate ...
 8-109 4.97e-05

uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.


Pssm-ID: 319909 [Multi-domain]  Cd Length: 117  Bit Score: 39.99  E-value: 4.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMTMREVDGTVDEPRQYWTLGGLQFIH--------NPKHDAPEGRLGHLGVMCED--- 76
Cdd:cd07245     1 LDHVALACPDLERARRFYTDVLGLEEVPRPPFLKFGGAWLYLGGGQQIHlvveqnpsELPRPEHPGRDRHPSFSVPDlda 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2502262303  77 MEAALAAAQ-KYDVSEMPQG---RNWLRLPDGLAIEL 109
Cdd:cd07245    81 LKQRLKEAGiPYTESTSPGGgvtQLFFRDPDGNRLEF 117
 
Name Accession Description Interval E-value
GloA COG0346
Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary ...
 8-115 1.74e-12

Catechol 2,3-dioxygenase or related enzyme, vicinal oxygen chelate (VOC) family [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440115 [Multi-domain]  Cd Length: 125  Bit Score: 59.62  E-value: 1.74e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMT--MREVDGTVDEPRQYWTLGG---LQFIHNPKHDAPE--GRLGHLGVMCEDMEAA 80
Cdd:COG0346     3 LHHVTLRVSDLEASLAFYTDVLGLElvKRTDFGDGGFGHAFLRLGDgteLELFEAPGAAPAPggGGLHHLAFRVDDLDAA 82

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 2502262303  81 LAAAQKYDVS------EMPQGRNWLRL--PDGLAIELIQARPA 115
Cdd:COG0346    83 YARLRAAGVEiegeprDRAYGYRSAYFrdPDGNLIELVEPPPG 125
CatE COG2514
Catechol-2,3-dioxygenase [Secondary metabolites biosynthesis, transport and catabolism];
8-125 1.61e-06

Catechol-2,3-dioxygenase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442004 [Multi-domain]  Cd Length: 141  Bit Score: 44.18  E-value: 1.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMT-MREVDGTVdeprQYWTLGG---LQFIHNPKHDAPEGRLG--HLGVMC---EDME 78
Cdd:COG2514     4 LGHVTLRVRDLERSAAFYTDVLGLEvVEREGGRV----YLRADGGehlLVLEEAPGAPPRPGAAGldHVAFRVpsrADLD 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 2502262303  79 AALAAAQKYDVSEMPQGRNW------LRLPDGLAIELIQARPASCVARALDID 125
Cdd:COG2514    80 AALARLAAAGVPVEGAVDHGvgeslyFRDPDGNLIELYTDRPRFEHVGDLETD 132
VOC COG3324
Lactoylglutathione lyase-related enzyme, vicinal oxygen chelate (VOC) family [General function ...
 10-114 2.51e-06

Lactoylglutathione lyase-related enzyme, vicinal oxygen chelate (VOC) family [General function prediction only];


Pssm-ID: 442553 [Multi-domain]  Cd Length: 119  Bit Score: 43.47  E-value: 2.51e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303  10 HVAIWVKDIHWHIRFFEDVFGMTMREVDGtvdEPRQYWTL-------GGLQfihnPKHDAPEGRLGHLGVMCEDMEAALA 82
Cdd:COG3324     7 WVELPVDDLERAKAFYEEVFGWTFEDDAG---PGGDYAEFdtdggqvGGLM----PGAEEPGGPGWLLYFAVDDLDAAVA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2502262303  83 AAQKYDV-------SEMPQGRN-WLRLPDGLAIELIQARP 114
Cdd:COG3324    80 RVEAAGGtvlrpptDIPPWGRFaVFRDPEGNRFGLWQPAA 119
Glyoxalase pfam00903
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;
8-109 3.90e-06

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;


Pssm-ID: 395724 [Multi-domain]  Cd Length: 121  Bit Score: 42.82  E-value: 3.90e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMTM--REVDGTVDEPRQYWTLGG-----LQFIHNPKHDAPEGRLGHLGVMC---EDM 77
Cdd:pfam00903   2 IDHVALRVGDLEKSLDFYTDVLGFKLveETDAGEEGGLRSAFFLAGgrvleLLLNETPPPAAAGFGGHHIAFIAfsvDDV 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 2502262303  78 EAALAAAQKYDVSEMP--------QGRNWLRLPDGLAIEL 109
Cdd:pfam00903  82 DAAYDRLKAAGVEIVRepgrhgwgGRYSYFRDPDGNLIEL 121
Glyoxalase_4 pfam13669
Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;
10-95 9.61e-06

Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;


Pssm-ID: 463951 [Multi-domain]  Cd Length: 109  Bit Score: 41.50  E-value: 9.61e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303  10 HVAIWVKDIHWHIRFFEDVFGMtmrEVDGTVDEPRQ----YWTLGG-----LQFIH----NPKHDAPEGRLGHLGVMCED 76
Cdd:pfam13669   2 HVGIAVPDLDRALALWGALLGL---GPEGDYRSEPQnvdlAFALLGdgpveVELIQpldgDSPLARHGPGLHHLAYWVDD 78

                          90
                  ....*....|....*....
gi 2502262303  77 MEAALAAAQKYDVSEMPQG 95
Cdd:pfam13669  79 LDAAVARLLDQGYRVAPKG 97
VOC_like cd07245
uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate ...
 8-109 4.97e-05

uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.


Pssm-ID: 319909 [Multi-domain]  Cd Length: 117  Bit Score: 39.99  E-value: 4.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMTMREVDGTVDEPRQYWTLGGLQFIH--------NPKHDAPEGRLGHLGVMCED--- 76
Cdd:cd07245     1 LDHVALACPDLERARRFYTDVLGLEEVPRPPFLKFGGAWLYLGGGQQIHlvveqnpsELPRPEHPGRDRHPSFSVPDlda 80

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2502262303  77 MEAALAAAQ-KYDVSEMPQG---RNWLRLPDGLAIEL 109
Cdd:cd07245    81 LKQRLKEAGiPYTESTSPGGgvtQLFFRDPDGNRLEF 117
VOC_like cd07254
uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate ...
 10-108 7.34e-05

uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.


Pssm-ID: 319917 [Multi-domain]  Cd Length: 120  Bit Score: 39.37  E-value: 7.34e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303  10 HVAIWVKDIHWHIRFFEDVFGMTMREVDG-----TVDEPRqywtlggLQFIHNPKHDAPEGRLGHLGVMCEDMEAALAAA 84
Cdd:cd07254     4 HLSLNVTDLERSIRFYSDLFGAEPAKRKAdyakfMLEDPP-------LNLALLVNDRKEPYGLNHLGIQVDSKEEVAALK 76

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2502262303  85 QKYDVSEMP-------------QGRNWLRLPDGLAIE 108
Cdd:cd07254    77 ARAEAAGLPvrkeprttccyavQDKFWLTDPDGNAWE 113
VOC cd06587
vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed ...
 10-109 2.42e-04

vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). Type I extradiol dioxygenases catalyze the incorporation of both atoms of molecular oxygen into aromatic substrates, which results in the cleavage of aromatic rings. They are key enzymes in the degradation of aromatic compounds. Type I extradiol dioxygenases include class I and class II enzymes. Class I and II enzymes show sequence similarity; the two-domain class II enzymes evolved from a class I enzyme through gene duplication. Glyoxylase I catalyzes the glutathione-dependent inactivation of toxic methylglyoxal, requiring zinc or nickel ions for activity. The antibiotic resistance proteins in this family use a variety of mechanisms to block the function of antibiotics. Bleomycin resistance protein (BLMA) sequesters bleomycin's activity by directly binding to it. Whereas, three types of fosfomycin resistance proteins employ different mechanisms to render fosfomycin inactive by modifying the fosfomycin molecule. Although the proteins in this superfamily are functionally distinct, their structures are similar. The difference among the three dimensional structures of the three types of proteins in this superfamily is interesting from an evolutionary perspective. Both glyoxalase I and BLMA show domain swapping between subunits. However, there is no domain swapping for type 1 extradiol dioxygenases.


Pssm-ID: 319898 [Multi-domain]  Cd Length: 112  Bit Score: 37.89  E-value: 2.42e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303  10 HVAIWVKDIHWHIRFFEDVFGMtmrEVDGTVDEPRQYW-TLGG---LQFIHNPKH-DAPEGRLGHLGVMCEDMEA----- 79
Cdd:cd06587     1 HVALRVPDLDASVAFYEEVLGF---EVVSRNEGGGFAFlRLGPglrLALLEGPEPeRPGGGGLFHLAFEVDDVDEvderl 77

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 2502262303  80 ALAAAQKYDVSEMPQGRN-----WLRLPDGLAIEL 109
Cdd:cd06587    78 REAGAEGELVAPPVDDPWggrsfYFRDPDGNLIEF 112
VOC_BsYqjT cd07242
vicinal oxygen chelate (VOC) family protein similar to Bacillus subtilis YqjT; The vicinal ...
 8-110 1.09e-03

vicinal oxygen chelate (VOC) family protein similar to Bacillus subtilis YqjT; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.


Pssm-ID: 319906  Cd Length: 126  Bit Score: 36.31  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMTMREVDGTVDEPRqyWTLGGLQFIHNPKHD---APEGR-----LGHLGVMCEDMEA 79
Cdd:cd07242     2 VSHVELAVSDLHRSFKWFEWILGLGWKEYDTWSFGPS--WKLSGGSLLVVQQTDefaTPEFDrarvgLNHLAFHAESREA 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 2502262303  80 -------------ALAAAQKYDVSEMPQGRN-WLRLPDGLAIELI 110
Cdd:cd07242    80 vdelteklakiggVRTYGDRHPFAGGPPHYAaFCEDPDGIKLELV 124
MMCE cd07249
Methylmalonyl-CoA epimerase (MMCE); MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) ...
 8-86 2.82e-03

Methylmalonyl-CoA epimerase (MMCE); MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.


Pssm-ID: 319912 [Multi-domain]  Cd Length: 127  Bit Score: 35.24  E-value: 2.82e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303   8 LEHVAIWVKDIHWHIRFFEDVFGMtmrEVDGTVDEPRQ-----YWTLGGLQF--IH--NPKH------DAPEGRLGHLGV 72
Cdd:cd07249     1 LDHIGIAVPDLDEALKFYEDVLGV---KVSEPEELEEQgvrvaFLELGNTQIelLEplGEDSpiakflDKKGGGLHHIAF 77

                          90
                  ....*....|....
gi 2502262303  73 MCEDMEAALAAAQK 86
Cdd:cd07249    78 EVDDIDAAVEELKA 91
VOC_like cd07264
uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate ...
 10-109 4.76e-03

uncharacterized subfamily of vicinal oxygen chelate (VOC) family; The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.


Pssm-ID: 319925 [Multi-domain]  Cd Length: 118  Bit Score: 34.61  E-value: 4.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2502262303  10 HVAIWVKDIHWHIRFFEDVFGMTMRevdgTVDEPRQYWTLG------GLQFIHNPKHDAPEGRLGH---LGVMCEDMEAA 80
Cdd:cd07264     3 YIVLYVDDFAASLRFYRDVLGLPPR----FLHEEGEYAEFDtgetklALFSRKEMARSGGPDRRGSafeLGFEVDDVEAT 78

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2502262303  81 LAAAQKYDVS------EMPQGRN--WLRLPDGLAIEL 109
Cdd:cd07264    79 VEELVERGAEfvrepaNKPWGQTvaYVRDPDGNLIEI 115
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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