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Conserved domains on  [gi|2495361178|ref|WP_279656153|]
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MULTISPECIES: sugar ABC transporter permease [unclassified Agrobacterium]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
30-314 5.78e-86

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 260.45  E-value: 5.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  30 SRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFHQWNMLpNSPMTLVGWSNYERIFALPKFWQALRNTGVYVLGLLPLAV 109
Cdd:COG1175    15 RRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLL-GPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 110 LIPLALAIYTHDlPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGMVNLIIKWFGFKPVQFLSDPQIAIWTVIAIT 189
Cdd:COG1175    94 VLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 190 GWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQwSFTYINILTQGGPLGS 269
Cdd:COG1175   173 VWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQ-VFDLVYVLTGGGPGNS 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2495361178 270 TTNIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:COG1175   252 TTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
30-314 5.78e-86

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 260.45  E-value: 5.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  30 SRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFHQWNMLpNSPMTLVGWSNYERIFALPKFWQALRNTGVYVLGLLPLAV 109
Cdd:COG1175    15 RRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLL-GPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 110 LIPLALAIYTHDlPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGMVNLIIKWFGFKPVQFLSDPQIAIWTVIAIT 189
Cdd:COG1175    94 VLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 190 GWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQwSFTYINILTQGGPLGS 269
Cdd:COG1175   173 VWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQ-VFDLVYVLTGGGPGNS 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2495361178 270 TTNIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:COG1175   252 TTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
37-314 5.96e-21

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 90.66  E-value: 5.96e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  37 LYLAPALITLIAWIYWPLVDAVRLSFHQWNMLPNSPmTLVGWSNYERIFA----LPKFWQALR-NTGVYVLGLLplAVLI 111
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSS-QFVGLDNFVALFHdsyyLDSFWTTIKfSTLVTVSGLL--VSLF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 112 PLALAIYThdlpARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGMVNLIIKWFGFKPVQFLSDPQiAIWTVIAITGW 191
Cdd:PRK10561   78 FAALVDYV----VRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQ-AMFLVVFASVW 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 192 KLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQWSFTYINILTQGGPLGSTT 271
Cdd:PRK10561  153 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATT 232

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2495361178 272 NIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:PRK10561  233 TLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVVQFRYVES 275
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 174-314 1.98e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 174 FLSDPQIAIWTVIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQW 253
Cdd:pfam00528  44 ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495361178 254 SFTyINILTQGGPLGSTTNIYYLLWDFGFSSmsvgWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:pfam00528 124 AVL-LEFLGSWPGLGLLLIEAILGYDYPEIQ----GPVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-299 2.81e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 49.97  E-value: 2.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  94 LRNTGVYVLGLLPLAVLIPLALAIYTHDLPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGmvnliikwfgfkpvq 173
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--------------- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 174 FLSDPQIAIWTVIAITGWkLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQW 253
Cdd:cd06261    66 WGILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2495361178 254 SFTyinILTQGGPLGSTTNIYYLLWDFGFSSMSVGWSSAAAVILFL 299
Cdd:cd06261   145 FAL---VSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
30-314 5.78e-86

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 260.45  E-value: 5.78e-86
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  30 SRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFHQWNMLpNSPMTLVGWSNYERIFALPKFWQALRNTGVYVLGLLPLAV 109
Cdd:COG1175    15 RRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLL-GPPPEFVGLDNYARLFTDPRFWNALGNTLLFTVVSVPLQL 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 110 LIPLALAIYTHDlPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGMVNLIIKWFGFKPVQFLSDPQIAIWTVIAIT 189
Cdd:COG1175    94 VLGLLLALLLNR-KLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGLLNALLGALGLEPINWLGDPSLALPAVIIVT 172

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 190 GWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQwSFTYINILTQGGPLGS 269
Cdd:COG1175   173 VWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQ-VFDLVYVLTGGGPGNS 251

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 2495361178 270 TTNIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:COG1175   252 TTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRR 296
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 1-248 1.08e-36

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 133.68  E-value: 1.08e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178   1 MADLALSPPAVAEKTRSPRsamgraLKIVSRHLSPWLYLAPALITLIAWIYWPLVdAVRLSFHQWNM---LPNSPmtLVG 77
Cdd:COG4209     1 MSTTAAKAKRKKKKRKKSF------LKRLKRDWQLYLMLLPGLIYLLIFSYLPMY-GIVIAFKDYNPfkgIFGSP--WVG 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  78 WSNYERIFALPKFWQALRNTGVYVLGLLPLAVLIPLALAIYTHDLPARW-RNIYRAIIFVPMIIAPVVAAAVWRWLLDPG 156
Cdd:COG4209    72 LKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFPLPIILALLLNELRSKRfKKTVQTISYLPHFLSWVVVAGIVYQFLSPD 151

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 157 FGMVNLIIKWFGFKPVQFLSDPQIAIWTVIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLS 236
Cdd:COG4209   152 TGLVNQLLRALGGEPINFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIR 231

                         250
                  ....*....|..
gi 2495361178 237 SSIlfmVMMTIL 248
Cdd:COG4209   232 PTI---VILLIL 240
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 29-314 4.99e-22

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 93.67  E-value: 4.99e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  29 VSRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFHQWNMLPNSPMTLvGWSNYERIFALPKFWQALRNTGVYVLGLLPLA 108
Cdd:COG1176     5 LRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGF-TLENYARLFTDPLYLKVLLRTLWIALLTTLIC 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 109 VLI--PLALAIYThdLPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGfGMVNLIIKWFGF--KPVQFLSDPqiaiWT 184
Cdd:COG1176    84 LLLgyPIAYFLAR--APPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRN-GLLNSLLLALGLidEPLRLLYTE----FA 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 185 VIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPL-----LSSSIL-FMVMMTillgaqwSFTYI 258
Cdd:COG1176   157 VVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLslpgiIAGSLLvFIPALG-------AFVTP 229

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 2495361178 259 NILtqGGPlgSTTNIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:COG1176   230 ALL--GGG--KVLMIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRR 281
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
37-314 5.96e-21

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 90.66  E-value: 5.96e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  37 LYLAPALITLIAWIYWPLVDAVRLSFHQWNMLPNSPmTLVGWSNYERIFA----LPKFWQALR-NTGVYVLGLLplAVLI 111
Cdd:PRK10561    1 LLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSS-QFVGLDNFVALFHdsyyLDSFWTTIKfSTLVTVSGLL--VSLF 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 112 PLALAIYThdlpARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGMVNLIIKWFGFKPVQFLSDPQiAIWTVIAITGW 191
Cdd:PRK10561   78 FAALVDYV----VRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQ-AMFLVVFASVW 152

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 192 KLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQWSFTYINILTQGGPLGSTT 271
Cdd:PRK10561  153 KQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRFFKLALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSGGPVQATT 232

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 2495361178 272 NIYYLLWDFGFSSMSVGWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:PRK10561  233 TLIYKIYREGFTGLDLSSSAAQSVVLMFLVIVLTVVQFRYVES 275
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
30-240 7.94e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 80.98  E-value: 7.94e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  30 SRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFHqwnmlpnspmtlVGWSNYERIFALPKFWQALRNTGVYVLGLLPLAV 109
Cdd:COG1178     4 RPRRRPRLLLLLLALLLALLVLLPLLALLLRAFT------------DGLANFWALLSDPYLWRALGNTLLLALLVTLLSL 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 110 LI--PLALAIYTHDLPARWrnIYRAIIFVPMIIAPVVAAAVWRWLLDPGfGMVN-LIIKWFGFKPVQFLSdpqiaIWTVI 186
Cdd:COG1178    72 LLgvPLAWLLARTDFPGRR--LLRWLLLLPLALPPYVVALAWIALFGPN-GLLNtLLRALFGLEPPDIYG-----LGGII 143

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....
gi 2495361178 187 AITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSIL 240
Cdd:COG1178   144 LVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIA 197
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 30-240 2.23e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 63.21  E-value: 2.23e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  30 SRHLSPWLYLAPALITLIaWIYWPLVDAVRLSFHQwNMLPNSPMTLVGWSNYERIFALPKFWQALRNTGVYVLGLLPLAV 109
Cdd:COG1177     1 SSRLGRLLLRLFLALVLL-FLYLPILVLVLYSFND-SWFLTFPPEGFTLRWYAELFSDPRLLDALLNSLLIALLSTLLAT 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 110 LIPLALAIYTHDLPARWRNIYRAIIFVPMIIAPVV-AAAVWRWLLDPGFGMvnliikwfgfkpvqflsdpqiAIWTVIAI 188
Cdd:COG1177    79 VLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVlGVALLLLFSALGLSG---------------------GLWGLILA 137

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 2495361178 189 TGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSIL 240
Cdd:COG1177   138 HVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGIL 189
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
12-245 1.02e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 59.40  E-value: 1.02e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  12 AEKTRSPRSAMGRALKIVSRHLSPWLYLAPALITLIAW--IYWPLVDAVRLSFhqwnmLPNSPMTLvGWSNYERIFALPK 89
Cdd:COG1178   262 LRRRRRYATVGGRARRPRRVKLGRWRWLALALCLLLVLlgLLLPLLALLLWSL-----TKALDDNL-TLDNYRFVLLDPS 335

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  90 FWQALRNTGVYVLGLLPLAVLIPLALAIYTHDLPARWRNIYRAIIFVPMIIAPVVAaavwrwlldpGFGMVNLIIKWFGF 169
Cdd:COG1178   336 LLRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVL----------GLGLLLLFNRPLPL 405

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2495361178 170 KPVQflsdpqiAIWTVIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMM 245
Cdd:COG1178   406 LLYG-------TLAILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALL 474
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 22-235 1.08e-09

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 58.18  E-value: 1.08e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  22 MGRALKIVSRHLSPWLYLAPALITLIAWIYwPLVDAVRLSFHQWNMLPNSPMTLV----GWSNYERIFALPKFWQALRNT 97
Cdd:COG0395     1 MSATARRRRRRLGRILLYLLLILLALLFLF-PLYWMVVTSFKPPAEIFSGPPSLLpsefTLENYRAAFTDGPFGRYLLNS 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  98 GVYVLGLLPLAVLIPL----ALAIYthdlPARWRNIYRAIIFVPMIIaPVVAAAVwrwlldPGFgmvnLIIKWFGfkpvq 173
Cdd:COG0395    80 LIVAVVSTVLSLLLSSlaayALARF----RFRGRKLLFLLILATLMI-PGQVLLI------PLY----LLFRQLG----- 139

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2495361178 174 fLSDPQIAIWTVIAITGwklIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLL 235
Cdd:COG0395   140 -LLNTYWGLILPYLAFG---LPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLS 197
malF PRK10999
maltose ABC transporter permease MalF;
76-311 1.45e-08

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 55.74  E-value: 1.45e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  76 VGWSNYERIFALPK----FWQALRNTGVYVLGLLPLAVLIPLALAIYTHDLPARWRNIYRAIIFVPMIIAPVVAAAVWRW 151
Cdd:PRK10999  265 IGWKNFTRVFTDEGiqkpFIAIFIWTVVFSLLTVVLTVAVGMVLACLVQWEALKGKAVYRVLLILPYAVPSFISILIFKG 344

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 152 LLDPGFGMVNLIIK-WFGFKPVQFlSDPQIAIWTVIAITGWklIGFSTL------ILSAananINPALIEAARMDGASKW 224
Cdd:PRK10999  345 LFNQSFGEINMMLSaLFGIKPAWF-SDPTLAKTMILIVNTW--LGYPYMmilcmgLLKA----IPDDLYEASAMDGAGPF 417

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 225 QIVRDIRLPLLsssilfMVMMTILLGAQWSFTY-----INILTQGGP--LGSTTNIYY--LLWDF-------GFSSMSVG 288
Cdd:PRK10999  418 QNFFKITLPLL------IKPLTPLMIASFAFNFnnfvlIQLLTNGGPdmIGTTTPAGYtdLLVSYtyriafeGGGGQDFG 491

                         250       260
                  ....*....|....*....|...
gi 2495361178 289 WSSAAAVILFLGFSAFAFLLFRL 311
Cdd:PRK10999  492 LAAAIATLIFLLVGALAILNLKA 514
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 174-314 1.98e-08

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 53.07  E-value: 1.98e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 174 FLSDPQIAIWTVIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQW 253
Cdd:pfam00528  44 ILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGG 123

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2495361178 254 SFTyINILTQGGPLGSTTNIYYLLWDFGFSSmsvgWSSAAAVILFLGFSAFAFLLFRLIDR 314
Cdd:pfam00528 124 AVL-LEFLGSWPGLGLLLIEAILGYDYPEIQ----GPVLAAALILLLLNLLVDILQRLLDP 179
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 94-299 2.81e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 49.97  E-value: 2.81e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  94 LRNTGVYVLGLLPLAVLIPLALAIYTHDLPARWRNIYRAIIFVPMIIAPVVAAAVWRWLLDPGFGmvnliikwfgfkpvq 173
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG--------------- 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 174 FLSDPQIAIWTVIAITGWkLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPLLSSSILFMVMMTILLGAQW 253
Cdd:cd06261    66 WGILPGLGLPALILALLL-IAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGE 144

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 2495361178 254 SFTyinILTQGGPLGSTTNIYYLLWDFGFSSMSVGWSSAAAVILFL 299
Cdd:cd06261   145 FAL---VSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLL 187
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 12-234 2.04e-05

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 45.38  E-value: 2.04e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  12 AEKTRSPRSAMGRALKIVSRHLSPWLYLAPALITLIAWIYWPLVDAVRLSFhqwnmlpnSPMTLVGWSNYERIFALPKFW 91
Cdd:PRK15050    1 AAARVRASAAAHAAAARRRRRLRPLLWLLLPLLVLAPLVVYPLVRVVLQSL--------TGEHGLGLATYRAVLGSPDFR 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  92 QALRNT----GVYVLGLLPLAVLIPLALAiythdlparwrniyraiiFVPMIIAPVVAAAVWRWLLDPGF---------- 157
Cdd:PRK15050   73 GALLTTlqiaFASTAGCLVLGVLLALVLA------------------FVPFPGASLVGRFIDTFVAFPSFlitlaftfly 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 158 ---GMVN-LIIKWFGFK--PVQFLSDPqiaiWTVIAITGWKLIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIR 231
Cdd:PRK15050  135 gsaGSVNiALQRLFGLEapPLDFLYSP----GGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVI 210


                  ...
gi 2495361178 232 LPL 234
Cdd:PRK15050  211 LPE 213
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 76-240 2.89e-03

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 38.58  E-value: 2.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178  76 VGWSNYERIFALPKFWQALRNT-GVYVLGLLPLAVL-IPLALAIYTHDLPARwrNIYRAIIFVPMIIAPVVAAAVWRWLL 153
Cdd:COG0555    38 LGWAEFWAVLTSPRVLAALKLSlGTALIAALINLVFgLPLAWVLVRYRFPGK--RLVDALVDLPFALPTAVAGIALLLLF 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2495361178 154 DPGfGMVNLIIKWFGFKpvqfLSDPQIAIWTVIAITGwklIGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLP 233
Cdd:COG0555   116 GPN-GWLGQLLAPLGIK----VAFTPLGIVLAQTFVS---LPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILP 187


                  ....*..
gi 2495361178 234 LLSSSIL 240
Cdd:COG0555   188 LLLPALL 194
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 194-251 4.59e-03

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 38.21  E-value: 4.59e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2495361178 194 IGFSTLILSAANANINPALIEAARMDGASKWQIVRDIRLPlLSSSILFMVMMTILLGA 251
Cdd:COG3833   155 IPFNTWLMKGYFDTIPKELDEAAKIDGASHFQIFFRIILP-LAKPILAVVALLSFIGP 211
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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