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Conserved domains on  [gi|2485504302|ref|WP_278339524|]
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MULTISPECIES: RteC domain-containing protein [Alistipes]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RteC super family cl09614
RteC protein; Human colonic Bacteroides species harbor a family of large conjugative ...
 86-198 1.62e-12

RteC protein; Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.


The actual alignment was detected with superfamily member pfam09357:

Pssm-ID: 430555  Cd Length: 218  Bit Score: 63.74  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485504302  86 IIAH----VEIERRILLVQLRYPALATRQSKHirsPYYWSAeyTLTDLMELISALHASGAIRkaDGTpAELNKLVRTFEL 161
Cdd:pfam09357 105 IIANellqEYLEKELEKLDNKIEEPSSPAPKK---KLKWTG--SKTALVELIYALHSSGVIN--NGN-ADIKDIARVFET 176

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2485504302 162 LLNVSFKNPDRCRNAALNRKVNVTKFLDALKQALVER 198
Cdd:pfam09357 177 LFNVDLGDYYRTFLEIKNRKKSRTKFLDKLKEALLKR 213
 
Name Accession Description Interval E-value
RteC pfam09357
RteC protein; Human colonic Bacteroides species harbor a family of large conjugative ...
 86-198 1.62e-12

RteC protein; Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.


Pssm-ID: 430555  Cd Length: 218  Bit Score: 63.74  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485504302  86 IIAH----VEIERRILLVQLRYPALATRQSKHirsPYYWSAeyTLTDLMELISALHASGAIRkaDGTpAELNKLVRTFEL 161
Cdd:pfam09357 105 IIANellqEYLEKELEKLDNKIEEPSSPAPKK---KLKWTG--SKTALVELIYALHSSGVIN--NGN-ADIKDIARVFET 176

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2485504302 162 LLNVSFKNPDRCRNAALNRKVNVTKFLDALKQALVER 198
Cdd:pfam09357 177 LFNVDLGDYYRTFLEIKNRKKSRTKFLDKLKEALLKR 213
 
Name Accession Description Interval E-value
RteC pfam09357
RteC protein; Human colonic Bacteroides species harbor a family of large conjugative ...
 86-198 1.62e-12

RteC protein; Human colonic Bacteroides species harbor a family of large conjugative transposons, called tetracycline resistance (Tcr) elements. Activities of these elements are enhanced by pregrowth of bacteria in medium containing tetracycline, indicating that at least some Tcr element genes are regulated by tetracycline. An insertional disruption in the rteC gene abolished self-transfer of the Tcr element to Bacteroides recipients, indicating that the gene was essential for self-transfer.


Pssm-ID: 430555  Cd Length: 218  Bit Score: 63.74  E-value: 1.62e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485504302  86 IIAH----VEIERRILLVQLRYPALATRQSKHirsPYYWSAeyTLTDLMELISALHASGAIRkaDGTpAELNKLVRTFEL 161
Cdd:pfam09357 105 IIANellqEYLEKELEKLDNKIEEPSSPAPKK---KLKWTG--SKTALVELIYALHSSGVIN--NGN-ADIKDIARVFET 176

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 2485504302 162 LLNVSFKNPDRCRNAALNRKVNVTKFLDALKQALVER 198
Cdd:pfam09357 177 LFNVDLGDYYRTFLEIKNRKKSRTKFLDKLKEALLKR 213
PEPcase pfam00311
Phosphoenolpyruvate carboxylase;
33-159 8.51e-03

Phosphoenolpyruvate carboxylase;


Pssm-ID: 425598  Cd Length: 920  Bit Score: 36.39  E-value: 8.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2485504302  33 ETAIEHFVERISRL-------LRKRPVIDQLRLLA-----HLCGYLERMKYRYAEEPikkgYfetiiahveierRILLVQ 100
Cdd:pfam00311 271 WLALDLYLKAIDALiaelsmsRHWSDVSDELLASLerdrqQLPEVYEFLSERYRQEP----Y------------RLKLAY 334

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2485504302 101 LRYPALATRQ----------SKHIRSPYYWSAEYTLTDLMELISALHASGAIRKADGTPAELNKLVRTF 159
Cdd:pfam00311 335 IRARLANTRDrlaaliagreAELPPGEIYRSAEELLEDLELIYRSLREHGGELLADGRLLDLIRQVEVF 403
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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