|
Name |
Accession |
Description |
Interval |
E-value |
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
27-477 |
1.81e-113 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 343.54 E-value: 1.81e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFfpsatqtvyDNVKYIAFRDTYGAADANYyyqQRWN----A 102
Cdd:PRK10938 25 TLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQF---------SHITRLSFEQLQKLVSDEW---QRNNtdmlS 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 103 HDQDET-PDVREM-LGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRE 180
Cdd:PRK10938 93 PGEDDTgRTTAEIiQDEVKDPARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILDEPFDGLDVASRQ 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 181 LLFSLLERLTKmSSVQIILVLSMLDDIPSFITHVIPVDKMEVFPKVEREAYLD-------AFRDRDIAVSFDELQKRIID 253
Cdd:PRK10938 173 QLAELLASLHQ-SGITLVLVLNRFDEIPDFVQFAGVLADCTLAETGEREEILQqalvaqlAHSEQLEGVQLPEPDEPSAR 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 254 --LPYDGNnydsdeVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYACDISLFGRKR 331
Cdd:PRK10938 252 haLPANEP------RIVLNNGVVSYNDRPILHNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 332 GTGESIWEIKKHIGYVSPEMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAG-LKDKPFLQLSSG 410
Cdd:PRK10938 326 GSGETIWDIKKHIGYVSSSLHLDYRVSTSVRNVILSGFFDSIGIYQAVSDRQQKLAQQWLDILGIDKrTADAPFHSLSWG 405
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 411 EQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNR 477
Cdd:PRK10938 406 QQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLISEGETQLLFVSHHAEDAPACITHR 472
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
264-485 |
3.11e-112 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 331.66 E-value: 3.11e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYACDISLFGRKRGtGESIWEIKKH 343
Cdd:COG1119 1 DPLLELRNVTVRRGGKTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVRLFGERRG-GEDVWELRKR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSPEMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVK 423
Cdd:COG1119 80 IGLVSPALQLRFPRDETVLDVVLSGFFDSIGLYREPTDEQRERARELLELLGLAHLADRPFGTLSQGEQRRVLIARALVK 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:COG1119 160 DPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRV 221
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
266-465 |
1.44e-42 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 151.35 E-value: 1.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRkrgtgeSIWEIK---- 341
Cdd:COG1120 1 MLEAENLSVGYGGRPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPS-SGEVLLDGR------DLASLSrrel 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 -KHIGYVSPEMHRAYlkNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARA 420
Cdd:COG1120 74 aRRIAYVPQEPPAPF--GLTVRELVALGRYPHLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARA 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1120 152 LAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLH 196
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
262-465 |
1.97e-40 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 145.62 E-value: 1.97e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS----LVcadNPQSyaCDISLFGRKRGTGesi 337
Cdd:COG1121 2 MMMPAIELENLTVSYGGRPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKailgLL---PPTS--GTVRLFGKPPRRA--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 weiKKHIGYVsPEmHRAYLKNLPA--IEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:COG1121 74 ---RRRIGYV-PQ-RAEVDWDFPItvRDVVLMGRYGRRGLFRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQQRV 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:COG1121 149 LLARALAQDPDLLLLDEPFAGVDAATEEALYELLREL-RREGKTILVVTH 197
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
265-470 |
3.85e-38 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 139.04 E-value: 3.85e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyaCDISLFGRKRGTGESiwEIKKH 343
Cdd:COG1131 2 EVRGLTK---RYGDKTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLgLLRPTS--GEVRVLGEDVARDPA--EVRRR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVsPEMHRAYlKNLPAIEIvasgLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVK 423
Cdd:COG1131 75 IGYV-PQEPALY-PDLTVREN----LRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLH 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESEL 470
Cdd:COG1131 149 DPELLILDEPTSGLDPEARRELWELLREL-AAEGKTVLLSTHYLEEA 194
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
18-465 |
2.32e-36 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 140.81 E-value: 2.32e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 18 VRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYP---LREGTLQYDFFPSATQTVYDNVKYIAfrdtygaadanY 94
Cdd:COG1123 19 VPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPhggRISGEVLLDGRDLLELSEALRGRRIG-----------M 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 95 YYQQRWNA-------HDQDETPDVREMLGEIKDEQLKnELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIM 167
Cdd:COG1123 88 VFQDPMTQlnpvtvgDQIAEALENLGLSRAEARARVL-ELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALALDPDLLIA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 168 DNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDKMEVfpkVEREAYLDAFRDRDIAVSFDEL 247
Cdd:COG1123 167 DEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRI---VEDGPPEEILAAPQALAAVPRL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 248 QKRIIDLPYDGNnyDSDEVVKLNKVSIRYDDR-----TILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSya 321
Cdd:COG1123 244 GAARGRAAPAAA--AAEPLLEVRNLSKRYPVRgkggvRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGlLRPTS-- 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 322 CDISLFGR--KRGTGESIWEIKKHIGYV--SPE-----MHRAYlknlpaiEIVASGLHdSIGLYKRPQPEQMAvcEWWMD 392
Cdd:COG1123 320 GSILFDGKdlTKLSRRSLRELRRRVQMVfqDPYsslnpRMTVG-------DIIAEPLR-LHGLLSRAERRERV--AELLE 389
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 393 IFGI-AGLKDK-PFlQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1123 390 RVGLpPDLADRyPH-ELSGGQrQRVAI-ARALALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISH 463
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
268-484 |
6.49e-35 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 129.51 E-value: 6.49e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDD--RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYACdisLFGRKRGTGESIWEIKKHI 344
Cdd:cd03225 1 ELKNLSFSYPDgaRPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGlLGPTSGEV---LVDGKDLTKLSLKELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYV--SPE----MHRAYlknlpaiEIVASGLhdsiGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLALl 417
Cdd:cd03225 78 GLVfqNPDdqffGPTVE-------EEVAFGL----ENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQkQRVAI- 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELPDTITNRIFLKRNQ 484
Cdd:cd03225 146 AGVLAMDPDILLLDEPTAGLDPAGRRELLELLKKL-KAEGKTIIIVTHDLDLLLELADRVIVLEDGK 211
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
268-465 |
7.33e-35 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 129.58 E-value: 7.33e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYACdISLFGRKrgtgesIWEIKKHIGYV 347
Cdd:cd03235 1 EVEDLTVSYGGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGS-IRVFGKP------LEKERKRIGYV 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 sPEmHRAYLKNLP--AIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDP 425
Cdd:cd03235 74 -PQ-RRSIDRDFPisVRDVVLMGLYGHKGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDP 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMIMVTH 465
Cdd:cd03235 152 DLLLLDEPFAGVDPKTQEDIYELLRELR-REGMTILVVTH 190
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
268-465 |
2.13e-34 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 127.17 E-value: 2.13e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPqSYACDISLFGRkrgtgeSIWEIK-----K 342
Cdd:cd03214 1 EVENLSVGYGGRTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLK-PSSGEILLDGK------DLASLSpkelaR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVspemhraylknlpaieivasglhdsiglykrPQpeqmavcewWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:cd03214 74 KIAYV-------------------------------PQ---------ALELLGLAHLADRPFNELSGGERQRVLLARALA 113
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03214 114 QEPPILLLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLH 156
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
268-465 |
2.21e-34 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 128.01 E-value: 2.21e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLvCADNPQSYACDISLFGRKRgTGESIWEIKKHIGYV 347
Cdd:COG4619 2 ELEGLSFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRA-LADLDPPTSGEIYLDGKPL-SAMPPPEWRRQVAYV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SPEmhraylknlPAI--EIVASGLhDSIGLYKRPQPEQMAVCEWwMDIFGI-AGLKDKPFLQLSSGE-QRLALLaRAFVK 423
Cdd:COG4619 80 PQE---------PALwgGTVRDNL-PFPFQLRERKFDRERALEL-LERLGLpPDILDKPVERLSGGErQRLALI-RALLL 147
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG4619 148 QPDVLLLDEPTSALDPENTRRVEELLREYLAEEGRAVLWVSH 189
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
266-473 |
1.21e-33 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 126.05 E-value: 1.21e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRkrGTGESIWEIKKHIG 345
Cdd:COG4133 2 MLEAENLSCRRGERLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPS-AGEVLWNGE--PIRDAREDYRRRLA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSpemHRAYLK-NLPAIEIVA--SGLHdsiglykRPQPEQMAVCEWwMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:COG4133 79 YLG---HADGLKpELTVRENLRfwAALY-------GLRADREAIDEA-LEAVGLAGLADLPVRQLSAGQKRRVALARLLL 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTHYESELPDT 473
Cdd:COG4133 148 SPAPLWLLDEPFTALDAAGVALLAELIAAHLARG-GAVLLTTHQPLELAAA 197
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
267-485 |
1.03e-32 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 122.51 E-value: 1.03e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGrkrgtgESIW----EIKK 342
Cdd:cd03230 1 IEVRNLSKRYGKKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPD-SGEIKVLG------KDIKkepeEVKR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSpemhraylknlpaieivasglhDSIGLYkrpqpEQMAVCEwwmdifgiaglkdkpFLQLSSGEQRLALLARAFV 422
Cdd:cd03230 74 RIGYLP----------------------EEPSLY-----ENLTVRE---------------NLKLSGGMKQRLALAQALL 111
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:cd03230 112 HDPELLILDEPTSGLDPESRREFWELLREL-KKEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
267-480 |
1.65e-31 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 120.90 E-value: 1.65e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRKRgTGESIWEIKKHI 344
Cdd:COG1122 1 IELENLSFSYpGGTPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGlLKPTS--GEVLVDGKDI-TKKNLRELRRKV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYV--SPEMHraylknlpaieIVASGLHDSI--GL--YKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLA 418
Cdd:COG1122 78 GLVfqNPDDQ-----------LFAPTVEEDVafGPenLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIA 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELPDtITNRIFL 480
Cdd:COG1122 147 GVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRL-NKEGKTVIIVTHDLDLVAE-LADRVIV 206
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
268-482 |
8.37e-31 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 116.58 E-value: 8.37e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGRKRGTgESIWEIKKHIGYV 347
Cdd:cd00267 1 EIENLSFRYGGRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSG-EILIDGKDIAK-LPLEELRRRIGYV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SpemhraylknlpaieivasglhdsiglykrpqpeqmavcewwmdifgiaglkdkpflQLSSGEQRLALLARAFVKDPEL 427
Cdd:cd00267 79 P---------------------------------------------------------QLSGGQRQRVALARALLLNPDL 101
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 428 LILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTHYESELPDTITNRIFLKR 482
Cdd:cd00267 102 LLLDEPTSGLDPASRERLLELLRELAEEG-RTVIIVTHDPELAELAADRVIVLKD 155
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
268-485 |
1.33e-30 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 118.81 E-value: 1.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSYACDISLFGRKRGTgesiWEIKKHIGY 346
Cdd:COG4555 3 EVENLSKKYGKVPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLlKPDSGSILIDGEDVRKEP----REARRQIGV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VsPEMHRAYlKNLPAIEIVASglhdSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPE 426
Cdd:COG4555 79 L-PDERGLY-DRLTVRENIRY----FAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPK 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 427 LLILDEPLHGLDTYNRRRVKKVIEAfCKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:COG4555 153 VLLLDEPTNGLDVMARRLLREILRA-LKKEGKTVLFSSHIMQEVEALCDRVVILHKGKV 210
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
267-465 |
2.30e-30 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 117.59 E-value: 2.30e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDD----RTILNELDWTVRRGEKWALSGENGAGKSTLLSLV-CADNPQS---YACDISLFGRKRGTGESIw 338
Cdd:cd03255 1 IELKNLSKTYGGggekVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILgGLDRPTSgevRVDGTDISKLSEKELAAF- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 eIKKHIGYVSPEMHraYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLALl 417
Cdd:cd03255 80 -RRRHIGFVFQSFN--LLPDLTALENVELPLL----LAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQqQRVAI- 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03255 152 ARALANDPKIILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTH 199
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
24-480 |
7.76e-27 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 113.24 E-value: 7.76e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQY-----------DFFPSATQTVYDNVkYIAFRDTYGAada 92
Cdd:COG0488 17 VSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDSGEVSIpkglrigylpqEPPLDDDLTVLDTV-LDGDAELRAL--- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 93 nyyyQQRWNA--HDQDETPDVREMLGEIKDE-------QLKNE----LFEL-FRIEPLlDKKIILLSSGELRKFQLTKTL 158
Cdd:COG0488 93 ----EAELEEleAKLAEPDEDLERLAELQEEfealggwEAEARaeeiLSGLgFPEEDL-DRPVSELSGGWRRRVALARAL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 159 LTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMssvqiILVLS----MLDDIpsfITHVIPVD--KMEVFP-------- 224
Cdd:COG0488 168 LSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPGT-----VLVVShdryFLDRV---ATRILELDrgKLTLYPgnysayle 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 225 -KVERE--------------AYLDAFRDRDI--------AVS----FDELQKriIDLPYDGNNYD---------SDEVVK 268
Cdd:COG0488 240 qRAERLeqeaaayakqqkkiAKEEEFIRRFRakarkakqAQSrikaLEKLER--EEPPRRDKTVEirfppperlGKKVLE 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyacdislfGR-KRGTGesiweIKkhIGY 346
Cdd:COG0488 318 LEGLSKSYGDKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAgELEPDS--------GTvKLGET-----VK--IGY 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSpeMHRAYLK-NLPAIEIVASGLHDsiglykRPQPEQMAVCEWwmdiFGIAGLK-DKPFLQLSSGEQ-RLAlLARAFVK 423
Cdd:COG0488 383 FD--QHQEELDpDKTVLDELRDGAPG------GTEQEVRGYLGR----FLFSGDDaFKPVGVLSGGEKaRLA-LAKLLLS 449
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFckrkDKTMIMVTHyESELPDTITNRIFL 480
Cdd:COG0488 450 PPNVLLLDEPTNHLDIETLEALEEALDDF----PGTVLLVSH-DRYFLDRVATRILE 501
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
27-246 |
7.25e-26 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 105.94 E-value: 7.25e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGkyplregtlqyDFFPSATQTVYdnvkyiAFRDTYGAAD--------------- 91
Cdd:COG1119 25 TVKPGEHWAILGPNGAGKSTLLSLITG-----------DLPPTYGNDVR------LFGERRGGEDvwelrkriglvspal 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 92 ANYYYQqrwnahdqDETpdVREM--------LG---EIKDEQLK--NELFELFRIEPLLDKKIILLSSGELRKFQLTKTL 158
Cdd:COG1119 88 QLRFPR--------DET--VLDVvlsgffdsIGlyrEPTDEQREraRELLELLGLAHLADRPFGTLSQGEQRRVLIARAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 159 LTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDKMEVF---PKVE--REAYLD 233
Cdd:COG1119 158 VKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVEEIPPGITHVLLLKDGRVVaagPKEEvlTSENLS 237
|
250
....*....|...
gi 2469828120 234 AFRDRDIAVSFDE 246
Cdd:COG1119 238 EAFGLPVEVERRD 250
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
267-465 |
1.14e-25 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 104.28 E-value: 1.14e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLFGRKRGTgesiwEIKKHIGY 346
Cdd:cd03269 1 LEVENVTKRFGRVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMI-LGIILPDSGEVLFDGKPLDI-----AARNRIGY 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VsPEMHRAYLKnlpaiEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPE 426
Cdd:cd03269 75 L-PEERGLYPK-----MKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPE 148
|
170 180 190
....*....|....*....|....*....|....*....
gi 2469828120 427 LLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:cd03269 149 LLILDEPFSGLDPVNVELLKDVIREL-ARAGKTVILSTH 186
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
267-474 |
2.15e-25 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 103.37 E-value: 2.15e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYacDISLFGRkRGTGESIWeiKKHIG 345
Cdd:cd03259 1 LELKGLSKTYGSVRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGlERPDSG--EILIDGR-DVTGVPPE--RRNIG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSpeMHRAYLKNLPAIEIVASGLhdsiGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDP 425
Cdd:cd03259 76 MVF--QDYALFPHLTVAENIAFGL----KLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREP 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE---LPDTI 474
Cdd:cd03259 150 SLLLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEalaLADRI 201
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
262-465 |
2.72e-25 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 109.08 E-value: 2.72e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDD-RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQsYACDISLFGRKRgTGESIWEI 340
Cdd:COG4988 332 AGPPSIELEDVSFSYPGgRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPP-YSGSILINGVDL-SDLDPASW 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHIGYVSpemHRAYLknlpaieiVASGLHDSIGLYkRPQ--PEQM-AVCEWwmdifgiAGLKDkpFLQ----------- 406
Cdd:COG4988 410 RRQIAWVP---QNPYL--------FAGTIRENLRLG-RPDasDEELeAALEA-------AGLDE--FVAalpdgldtplg 468
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 407 -----LSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkrKDKTMIMVTH 465
Cdd:COG4988 469 eggrgLSGGQaQRLAL-ARALLRDAPLLLLDEPTAHLDAETEAEILQALRRLA--KGRTVILITH 530
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
266-465 |
3.30e-25 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 105.19 E-value: 3.30e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTL----LSLVCADnpqsyACDISLFGRKRGtgesiWEIK 341
Cdd:COG4152 1 MLELKGLTKRFGDKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTiriiLGILAPD-----SGEVLWDGEPLD-----PEDR 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVsPEmHRAYLKNLPAIEIVA--SGLHdsiGLYKRPQPEQMavcEWWMDIFGIAGLKDKPFLQLSSGE-QRLALLA 418
Cdd:COG4152 71 RRIGYL-PE-ERGLYPKMKVGEQLVylARLK---GLSKAEAKRRA---DEWLERLGLGDRANKKVEELSKGNqQKVQLIA 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 419 rAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:COG4152 143 -ALLHDPELLILDEPFSGLDPVNVELLKDVIREL-AAKGTTVIFSSH 187
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
267-465 |
6.35e-25 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 100.92 E-value: 6.35e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRT--ILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQS---YACDISLfgrkrgTGESIWEI 340
Cdd:cd03228 1 IEFKNVSFSYPGRPkpVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRlYDPTSgeiLIDGVDL------RDLDLESL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHIGYVSpemHRAYLknlpaieivasgLHDSIglykrpqpeqmavcewwMD-IfgiaglkdkpflqLSSGE-QRLALlA 418
Cdd:cd03228 75 RKNIAYVP---QDPFL------------FSGTI-----------------REnI-------------LSGGQrQRIAI-A 108
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:cd03228 109 RALLRDPPILILDEATSALDPETEALILEALRAL--AKGKTVIVIAH 153
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
271-485 |
2.45e-24 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 100.41 E-value: 2.45e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 271 KVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNpQSYACDISLFGRKRgtgeSIWEIKKHIGYVSP 349
Cdd:cd03226 4 NISFSYkKGTEILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLI-KESSGSILLNGKPI----KAKERRKSIGYVMQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EMHRAYLKnlpaiEIVASGLHDSIGLYKRPQPEQMAVcewwMDIFGIAGLKDKPFLQLSSGE-QRLALlARAFVKDPELL 428
Cdd:cd03226 79 DVDYQLFT-----DSVREELLLGLKELDAGNEQAETV----LKDLDLYALKERHPLSLSGGQkQRLAI-AAALLSGKDLL 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 429 ILDEPLHGLDTYNRRRVKKVIEAfCKRKDKTMIMVTHyESELPDTITNR-IFLKRNQV 485
Cdd:cd03226 149 IFDEPTSGLDYKNMERVGELIRE-LAAQGKAVIVITH-DYEFLAKVCDRvLLLANGAI 204
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
282-433 |
3.24e-24 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 98.10 E-value: 3.24e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCAdNPQSYACDISLFGRkRGTGESIWEIKKHIGYVSPEMHraYLKNLPA 361
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAG-LLSPTEGTILLDGQ-DLTDDERKSLRKEIGYVFQDPQ--LFPRLTV 76
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 362 IEIVASGLHDSiGLYKRPQPEQMavcEWWMDIFGIAGLKDKPFL----QLSSGEQRLALLARAFVKDPELLILDEP 433
Cdd:pfam00005 77 RENLRLGLLLK-GLSKREKDARA---EEALEKLGLGDLADRPVGerpgTLSGGQRQRVAIARALLTKPKLLLLDEP 148
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
232-485 |
2.54e-23 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 102.92 E-value: 2.54e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 232 LDAFRDRDIAVSFdelqkriidlPYDGNNYDSDEVVKLNKVSIRYDD--RTILNELDWTVRRGEKWALSGENGAGKSTLL 309
Cdd:COG4987 309 LNELLDAPPAVTE----------PAEPAPAPGGPSLELEDVSFRYPGagRPVLDGLSLTLPPGERVAIVGPSGSGKSTLL 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 310 SLVC-ADNPQSYacDISLFGR--KRGTGESIWEikkHIGYVSpemHRAYLknlpaieivasgLHDSIG---LYKRPQ--P 381
Cdd:COG4987 379 ALLLrFLDPQSG--SITLGGVdlRDLDEDDLRR---RIAVVP---QRPHL------------FDTTLRenlRLARPDatD 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 382 EQM-AVCEwwmdifgIAGLKDkpFL----------------QLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRR 443
Cdd:COG4987 439 EELwAALE-------RVGLGD--WLaalpdgldtwlgeggrRLSGGErRRLAL-ARALLRDAPILLLDEPTEGLDAATEQ 508
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2469828120 444 RVKKVIEAFCkrKDKTMIMVTHYESELP--DTItnrIFLKRNQV 485
Cdd:COG4987 509 ALLADLLEAL--AGRTVLLITHRLAGLErmDRI---LVLEDGRI 547
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
264-465 |
4.10e-23 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 97.42 E-value: 4.10e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYDD----RTILNELDWTVRRGEKWALSGENGAGKSTLLSLV-CADNPQSyacdislfgrkrGT----G 334
Cdd:COG1136 2 SPLLELRNLTKSYGTgegeVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILgGLDRPTS------------GEvlidG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 335 ESIWEIK---------KHIGYVSPEMHraYLKNLPAIEIVASGLHdsIGLYKRPQPEQMAvcEWWMDIFGIAGLKDKPFL 405
Cdd:COG1136 70 QDISSLSerelarlrrRHIGFVFQFFN--LLPELTALENVALPLL--LAGVSRKERRERA--RELLERVGLGDRLDHRPS 143
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 406 QLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1136 144 QLSGGQqQRVAI-ARALVNRPKLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTH 203
|
|
| FtsE |
TIGR02673 |
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC ... |
266-478 |
3.91e-22 |
|
cell division ATP-binding protein FtsE; This model describes FtsE, a member of the ABC transporter ATP-binding protein family. This protein, and its permease partner FtsX, localize to the division site. In a number of species, the ftsEX gene pair is located next to FtsY, the signal recognition particle-docking protein. [Cellular processes, Cell division]
Pssm-ID: 131721 [Multi-domain] Cd Length: 214 Bit Score: 94.24 E-value: 3.91e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYD-DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPqsYACDISLFGR--KRGTGESIWEIK 341
Cdd:TIGR02673 1 MIEFHNVSKAYPgGVAALHDVSLHIRKGEFLFLTGPSGAGKTTLLKLLYgALTP--SRGQVRIAGEdvNRLRGRQLPLLR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVSPEMHraYLKNLPAIEIVASGLHdSIGLYKRPQPEQM-AVCEWwmdifgiAGLKDKPF---LQLSSGEQRLALL 417
Cdd:TIGR02673 79 RRIGVVFQDFR--LLPDRTVYENVALPLE-VRGKKEREIQRRVgAALRQ-------VGLEHKADafpEQLSGGEQQRVAI 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHyESELPDTITNRI 478
Cdd:TIGR02673 149 ARAIVNSPPLLLADEPTGNLDPDLSERILDLLKRLNKR-GTTVIVATH-DLSLVDRVAHRV 207
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
267-465 |
4.15e-22 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 94.46 E-value: 4.15e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDR----TILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWEIK 341
Cdd:cd03293 1 LEVRNVSKTYGGGggavTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGlERPTS--------GEVLVDGEPVTGPG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVspeMHRAYLknLP---AIEIVASGLhdsiGLYKRPQPEQMAVCEWWMDIFGIAGLKDK-PFlQLSSG-EQRLAL 416
Cdd:cd03293 73 PDRGYV---FQQDAL--LPwltVLDNVALGL----ELQGVPKAEARERAEELLELVGLSGFENAyPH-QLSGGmRQRVAL 142
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 417 lARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03293 143 -ARALAVDPDVLLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTH 190
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
263-465 |
4.74e-22 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 95.16 E-value: 4.74e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRY----DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESI 337
Cdd:COG1116 4 AAPALELRGVSKRFptggGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGlEKPTS--------GEVLVDGKPV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 WEIKKHIGYVSPEmhrAYLknLP---AIEIVASGLHDSiglyKRPQPEQMAVCEWWMDIFGIAGLKDK-PFlQLSSGE-Q 412
Cdd:COG1116 76 TGPGPDRGVVFQE---PAL--LPwltVLDNVALGLELR----GVPKAERRERARELLELVGLAGFEDAyPH-QLSGGMrQ 145
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 413 RLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1116 146 RVAI-ARALANDPEVLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTH 197
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
267-484 |
6.05e-22 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 91.74 E-value: 6.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSyacdislfgrkrgtGESIWEIKKHIG 345
Cdd:cd03221 1 IELENLSKTYGGKLLLKDISLTINPGDRIGLVGRNGAGKSTLLKlIAGELEPDE--------------GIVTWGSTVKIG 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSpemhraylknlpaieivasglhdsiglykrpqpeqmavcewwmdifgiaglkdkpflQLSSGEQRLALLARAFVKDP 425
Cdd:cd03221 67 YFE---------------------------------------------------------QLSGGEKMRLALAKLLLENP 89
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 426 ELLILDEPLHGLDTYNRrrvkKVIEAFCKRKDKTMIMVTHyESELPDTITNRIFLKRNQ 484
Cdd:cd03221 90 NLLLLDEPTNHLDLESI----EALEEALKEYPGTVILVSH-DRYFLDQVATKIIELEDG 143
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
266-468 |
9.58e-22 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 93.58 E-value: 9.58e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGR--KRGTGESIWEIKK 342
Cdd:COG2884 1 MIRFENVSKRYpGGREALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSG-QVLVNGQdlSRLKRREIPYLRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSPEmHRaYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:COG2884 80 RIGVVFQD-FR-LLPDRTVYENVALPLR----VTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALV 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTHYES 468
Cdd:COG2884 154 NRPELLLADEPTGNLDPETSWEIMELLEEINRRG-TTVLIATHDLE 198
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
266-465 |
9.68e-22 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 98.05 E-value: 9.68e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyaCDIS---LFGRKRGTGESIWEI 340
Cdd:COG1123 4 LLEVRDLSVRYpgGDVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHG--GRISgevLLDGRDLLELSEALR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHIGYVSPEmHRAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARA 420
Cdd:COG1123 82 GRRIGMVFQD-PMTQLNPVTVGDQIAEALE----NLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMA 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1123 157 LALDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITH 201
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
275-478 |
3.34e-21 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 92.05 E-value: 3.34e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIW----EIKKHIGYVSP 349
Cdd:cd03265 9 KYGDFEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTlLKPTS--------GRATVAGHDVVreprEVRRRIGIVFQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EmhRAYLKNLPAIEIVAsgLHDSIGLYKRPQPEQMAvcEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLI 429
Cdd:cd03265 81 D--LSVDDELTGWENLY--IHARLYGVPGAERRERI--DELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEVLF 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 430 LDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESElPDTITNRI 478
Cdd:cd03265 155 LDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEE-AEQLCDRV 202
|
|
| thiQ |
TIGR01277 |
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ... |
267-486 |
6.11e-21 |
|
thiamine ABC transporter, ATP-binding protein; This model describes the energy-transducing ATPase subunit ThiQ of the ThiBPQ thiamine (and thiamine pyrophosphate) ABC transporter in several Proteobacteria. This protein is found so far only in Proteobacteria, and is found in complete genomes only if the ThiB and ThiP subunits are also found. [Transport and binding proteins, Other]
Pssm-ID: 130344 [Multi-domain] Cd Length: 213 Bit Score: 91.08 E-value: 6.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfgrkrgtGESIWEIKKHIG 345
Cdd:TIGR01277 1 LALDKV--RYEYEHLPMEFDLNVADGEIVAIMGPSGAGKSTLLNLIAGfIEPAS--------------GSIKVNDQSHTG 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 yvSPEMHRAY---------LKNLPAIEIVASGLHDSIGLyKRPQPEQM--AVCEwwmdiFGIAGLKDKPFLQLSSGEQRL 414
Cdd:TIGR01277 65 --LAPYQRPVsmlfqennlFAHLTVRQNIGLGLHPGLKL-NAEQQEKVvdAAQQ-----VGIADYLDRLPEQLSGGQRQR 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 415 ALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLKRNQVS 486
Cdd:TIGR01277 137 VALARCLVRPNPILLLDEPFSALDPLLREEMLALVKQLCSERQRTLLMVTHHLSDARAIASQIAVVSQGKIK 208
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
267-465 |
7.56e-21 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 93.62 E-value: 7.56e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcA--DNPQSyaCDISLFGR--------KRGtges 336
Cdd:COG3842 6 LELENVSKRYGDVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMI-AgfETPDS--GRILLDGRdvtglppeKRN---- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 337 iweikkhIGYVS------PemhraylkNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKD-KPFlQLSS 409
Cdd:COG3842 79 -------VGMVFqdyalfP--------HLTVAENVAFGLR----MRGVPKAEIRARVAELLELVGLEGLADrYPH-QLSG 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 410 GE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG3842 139 GQqQRVAL-ARALAPEPRVLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTH 194
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
265-465 |
1.32e-20 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 90.26 E-value: 1.32e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKVsIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRKRGTgeSIWEIKKHI 344
Cdd:cd03263 2 QIRNLTKT-YKKGTKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPT-SGTAYINGYSIRT--DRKAARQSL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVsPEmHRAYLKNLPAIEIVA--SGLHdsiGLYKRpqpEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:cd03263 78 GYC-PQ-FDALFDELTVREHLRfyARLK---GLPKS---EIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALI 149
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:cd03263 150 GGPSVLLLDEPTSGLDPASRRAIWDLILEV--RKGRSIILTTH 190
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
267-485 |
1.47e-20 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 94.90 E-value: 1.47e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRT--ILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfgrkrGT----GESIWE 339
Cdd:COG2274 474 IELENVSFRYPGDSppVLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGlYEPTS------------GRilidGIDLRQ 541
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IK-----KHIGYVSPE---MHRAYLKNL----PAI---EIVA----SGLHDSIglYKRPQPEQMAVCEwwmdiFGIaglk 400
Cdd:COG2274 542 IDpaslrRQIGVVLQDvflFSGTIRENItlgdPDAtdeEIIEaarlAGLHDFI--EALPMGYDTVVGE-----GGS---- 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 401 dkpflQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkrKDKTMIMVTHYESelpdTITN--R 477
Cdd:COG2274 611 -----NLSGGQrQRLAI-ARALLRNPRILILDEATSALDAETEAIILENLRRLL--KGRTVIIIAHRLS----TIRLadR 678
|
....*....
gi 2469828120 478 IF-LKRNQV 485
Cdd:COG2274 679 IIvLDKGRI 687
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
267-478 |
1.61e-20 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 90.25 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRKRG--TGESIWEIKKH 343
Cdd:cd03261 1 IELRGLTKSFGGRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGlLRPDS--GEVLIDGEDISglSEAELYRLRRR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSpeMHRAYLKNLPAIEIVASGLHDsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVK 423
Cdd:cd03261 79 MGMLF--QSGALFDSLTVFENVAFPLRE---HTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALAL 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELpDTITNRI 478
Cdd:cd03261 154 DPELLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTA-FAIADRI 207
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
270-465 |
1.78e-20 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 90.60 E-value: 1.78e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 270 NKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPqSYACDISLFGRKRgTGESIWEIKKHigyvsp 349
Cdd:PRK13548 6 RNLSVRLGGRTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGELS-PDSGEVRLNGRPL-ADWSPAELARR------ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 emhRAYLKN-------LPAIEIVASGLHDsiglYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:PRK13548 78 ---RAVLPQhsslsfpFTVEEVVAMGRAP----HGLSRAEDDALVAAALAQVDLAHLAGRDYPQLSGGEQQRVQLARVLA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 423 ------KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13548 151 qlwepdGPPRWLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLH 199
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
267-485 |
2.17e-20 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 89.17 E-value: 2.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGeKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGRKrgTGESIWEIKKHIGY 346
Cdd:cd03264 1 LQLENLTKRYGKKRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSG-TIRIDGQD--VLKQPQKLRRRIGY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VsPEMHRAYlKNLPAIEIVasglhDSIGLYKR-PQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSG-EQRLALlARAFVKD 424
Cdd:cd03264 77 L-PQEFGVY-PNFTVREFL-----DYIAWLKGiPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGmRRRVGI-AQALVGD 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 425 PELLILDEPLHGLDTYNRRRVKKVIEAFCkrKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:cd03264 149 PSILIVDEPTAGLDPEERIRFRNLLSELG--EDRIVILSTHIVEDVESLCNQVAVLNKGKL 207
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
267-483 |
3.06e-20 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 88.01 E-value: 3.06e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSyaCDISLFGRKRGTGESIW-EIKKHI 344
Cdd:cd03229 1 LELKNVSKRYGQKTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRcIAGLEEPDS--GSILIDGEDLTDLEDELpPLRRRI 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMhrAYLKNLPAIEIVAsglhdsiglykrpqpeqmavcewwmdifgiaglkdkpfLQLSSGE-QRLALlARAFVK 423
Cdd:cd03229 79 GMVFQDF--ALFPHLTVLENIA--------------------------------------LGLSGGQqQRVAL-ARALAM 117
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELpDTITNRIFLKRN 483
Cdd:cd03229 118 DPDVLLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEA-ARLADRVVVLRD 176
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
262-465 |
4.27e-20 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 89.03 E-value: 4.27e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDR----TILNELDWTVRRGEKWALSGENGAGKSTLLSLvCA--DNPQS---YACDISLF----- 327
Cdd:COG4181 4 SSAPIIELRGLTKTVGTGagelTILKGISLEVEAGESVAIVGASGSGKSTLLGL-LAglDRPTSgtvRLAGQDLFalded 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 328 GRKRGTGEsiweikkHIGYVSPEMHraYLKNLPAIEIVASGLHdsigLYKRPQPEQMAvcEWWMDIFGIAGLKDKPFLQL 407
Cdd:COG4181 83 ARARLRAR-------HVGFVFQSFQ--LLPTLTALENVMLPLE----LAGRRDARARA--RALLERVGLGHRLDHYPAQL 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 408 SSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG4181 148 SGGEQQRVALARAFATEPAILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTH 205
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
269-479 |
6.52e-20 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 92.44 E-value: 6.52e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnpqsyACDISLFGrkrgtGESIWEIKKHIGYVS 348
Cdd:COG0488 1 LENLSKSFGGRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKIL--------AGELEPDS-----GEVSIPKGLRIGYLP 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 349 PEMHraYLKNLPAIEIVASGLHDSIGLYKR------------PQPEQMAVCEWWMDIFG-----------IAGLK----- 400
Cdd:COG0488 68 QEPP--LDDDLTVLDTVLDGDAELRALEAEleeleaklaepdEDLERLAELQEEFEALGgweaearaeeiLSGLGfpeed 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 401 -DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDtynrrrvkkvIEA------FCKRKDKTMIMVTH--YeseLP 471
Cdd:COG0488 146 lDRPVSELSGGWRRRVALARALLSEPDLLLLDEPTNHLD----------LESiewleeFLKNYPGTVLVVSHdrY---FL 212
|
....*...
gi 2469828120 472 DTITNRIF 479
Cdd:COG0488 213 DRVATRIL 220
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
268-465 |
6.59e-20 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 88.78 E-value: 6.59e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSYAcdISLFGRKRGT--GESIWEIKKH 343
Cdd:cd03256 2 EVENLSKTYpNGKKALKDVSLSINPGEFVALIGPSGAGKSTLLrCLNGLVEPTSGS--VLIDGTDINKlkGKALRQLRRQ 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSpeMHRAYLKNLPAIEIVASGLHDSI----GLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLAR 419
Cdd:cd03256 80 IGMIF--QQFNLIERLSVLENVLSGRLGRRstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIAR 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 420 AFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03256 158 ALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLH 203
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
276-476 |
5.46e-19 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 89.30 E-value: 5.46e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 276 YDDRT-ILNELdwTVRRGEKWALSGENGAGKSTLLSLVCADNPQ---SYACDISlfgrkRGTGESIWEIKKhigYVSPEM 351
Cdd:PRK10938 14 SDTKTlQLPSL--TLNAGDSWAFVGANGSGKSALARALAGELPLlsgERQSQFS-----HITRLSFEQLQK---LVSDEW 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 HRAYLKNLP---------AIEIVASGLHDSiglykrpqpeqmAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:PRK10938 84 QRNNTDMLSpgeddtgrtTAEIIQDEVKDP------------ARCEQLAQQFGITALLDRRFKYLSTGETRKTLLCQALM 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTHYESELPDTITN 476
Cdd:PRK10938 152 SEPDLLILDEPFDGLDVASRQQLAELLASLHQSG-ITLVLVLNRFDEIPDFVQF 204
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
267-480 |
8.03e-19 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 85.37 E-value: 8.03e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWEI---KK 342
Cdd:cd03300 1 IELENVSKFYGGFVALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGfETPTS--------GEILLDGKDITNLpphKR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSpeMHRAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:cd03300 73 PVNTVF--QNYALFPHLTVFENIAFGLR----LKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALV 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPdTITNRIFL 480
Cdd:cd03300 147 NEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEAL-TMSDRIAV 203
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
267-476 |
9.69e-19 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 85.36 E-value: 9.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDD-RTILNELDWTVRRGEKWALSGENGAGKSTLLSLvcadnpqsyacdisLF-------GRKRGTGESIW 338
Cdd:cd03253 1 IEFENVTFAYDPgRPVLKDVSFTIPAGKKVAIVGPSGSGKSTILRL--------------LFrfydvssGSILIDGQDIR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIK-----KHIGYVsPE---------MHRAYLKNLPA--IEIV----ASGLHDSIglykrpqpeqMAVCEWWMDIFGIAG 398
Cdd:cd03253 67 EVTldslrRAIGVV-PQdtvlfndtiGYNIRYGRPDAtdEEVIeaakAAQIHDKI----------MRFPDGYDTIVGERG 135
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 399 LKdkpflqLSSGE-QRLAlLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkdKTMIMVTHYESelpdTITN 476
Cdd:cd03253 136 LK------LSGGEkQRVA-IARAILKNPPILLLDEATSALDTHTEREIQAALRDVSKG--RTTIVIAHRLS----TIVN 201
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
272-465 |
1.43e-18 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 84.80 E-value: 1.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRkRGTGESIWEIKKHiGyvspeM 351
Cdd:cd03219 6 LTKRFGGLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPT-SGSVLFDGE-DITGLPPHEIARL-G-----I 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 HRAY-----LKNLPAIE--IVA----SGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARA 420
Cdd:cd03219 78 GRTFqiprlFPELTVLEnvMVAaqarTGSGLLLARARREEREARERAEELLERVGLADLADRPAGELSYGQQRRLEIARA 157
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:cd03219 158 LATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLVEH 201
|
|
| PhnT2 |
TIGR03265 |
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ... |
263-469 |
2.02e-18 |
|
putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; This ABC transporter ATP-binding protein is found in a number of genomes in operon-like contexts strongly suggesting a substrate specificity for 2-aminoethylphosphonate (2-AEP). The characterized PhnSTUV system is absent in the genomes in which this system is found. These genomes encode systems for the catabolism of 2-AEP, making the need for a 2-AEP-specific transporter likely. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274496 [Multi-domain] Cd Length: 353 Bit Score: 86.63 E-value: 2.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCadnpqsyacdislfGRKRGTGESIWEIKK 342
Cdd:TIGR03265 1 SSPYLSIDNIRKRFGAFTALKDISLSVKKGEFVCLLGPSGCGKTTLLRIIA--------------GLERQTAGTIYQGGR 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSPEMhRAY---------LKNLPAIEIVASGLHDSiglyKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQR 413
Cdd:TIGR03265 67 DITRLPPQK-RDYgivfqsyalFPNLTVADNIAYGLKNR----GMGRAEVAERVAELLDLVGLPGSERKYPGQLSGGQQQ 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 414 LALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:TIGR03265 142 RVALARALATSPGLLLLDEPLSALDARVREHLRTEIRQLQRRLGVTTIMVTHDQEE 197
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
267-470 |
2.65e-18 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 83.42 E-value: 2.65e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRKRGTGESIWeikKHIGy 346
Cdd:cd03268 1 LKTNDLTKTYGKKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPD-SGEITFDGKSYQKNIEAL---RRIG- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEMHRAYLkNLPAIE-IVASGLhdsigLYKRPQPEQMAVcewwMDIFGIAGLKDKPFLQLSSG-EQRLAlLARAFVKD 424
Cdd:cd03268 76 ALIEAPGFYP-NLTAREnLRLLAR-----LLGIRKKRIDEV----LDVVGLKDSAKKKVKGFSLGmKQRLG-IALALLGN 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 425 PELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESEL 470
Cdd:cd03268 145 PDLLILDEPTNGLDPDGIKELRELILSL-RDQGITVLISSHLLSEI 189
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
267-465 |
2.94e-18 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 87.53 E-value: 2.94e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYD-DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC--ADnPQSyacdislfgrkrGT----GESIWE 339
Cdd:COG1132 340 IEFENVSFSYPgDRPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLrfYD-PTS------------GRilidGVDIRD 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IK-----KHIGYVSpemHRAYLknlpaieivasgLHDSIG---LYKRPQ--PEQM-AVCEwwmdifgIAGLKDkpFLQ-- 406
Cdd:COG1132 407 LTleslrRQIGVVP---QDTFL------------FSGTIReniRYGRPDatDEEVeEAAK-------AAQAHE--FIEal 462
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 407 --------------LSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:COG1132 463 pdgydtvvgergvnLSGGQrQRIAI-ARALLKDPPILILDEATSALDTETEALIQEALERL--MKGRTTIVIAH 533
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
267-485 |
3.02e-18 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 83.31 E-value: 3.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTIlnELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYAcdISLFGRKRGTGESIweiKKHIG 345
Cdd:cd03298 1 VRLDKIRFSYGEQPM--HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGfETPQSGR--VLINGVDVTAAPPA---DRPVS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPEmhraylKNLPAIEIVAS--GLHDSIGLYKRPQPEQ-MAVCEWWMdifGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:cd03298 74 MLFQE------NNLFAHLTVEQnvGLGLSPGLKLTAEDRQaIEVALARV---GLAGLEKRLPGELSGGERQRVALARVLV 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:cd03298 145 RDKPVLLLDEPFAALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRI 207
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
263-465 |
6.77e-18 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 83.16 E-value: 6.77e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyaCDISLFGRKRgTGESIWEIK 341
Cdd:COG0411 1 SDPLLEVRGLTKRFGGLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITgFYRPTS--GRILFDGRDI-TGLPPHRIA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHiGyvspeMHRAY-----LKNLPAIEIVASGLH-----------DSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFL 405
Cdd:COG0411 78 RL-G-----IARTFqnprlFPELTVLENVLVAAHarlgrgllaalLRLPRARREEREARERAEELLERVGLADRADEPAG 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 406 QLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG0411 152 NLSYGQQRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEH 211
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
262-465 |
7.02e-18 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 86.19 E-value: 7.02e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDRT-ILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLFGRK-RGTGESIWe 339
Cdd:TIGR02857 317 APASSLEFSGVSVAYPGRRpALRPVSFTVPPGERVALVGPSGAGKSTLLNLL-LGFVDPTEGSIAVNGVPlADADADSW- 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 iKKHIGYVSpemHRAYlknlpaieIVASGLHDSIGLYKRPQPEQMaVCEWWMDifgiAGLKDkpFLQ------------- 406
Cdd:TIGR02857 395 -RDQIAWVP---QHPF--------LFAGTIAENIRLARPDASDAE-IREALER----AGLDE--FVAalpqgldtpigeg 455
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 407 ---LSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkdKTMIMVTH 465
Cdd:TIGR02857 456 gagLSGGQaQRLAL-ARAFLRDAPLLLLDEPTAHLDAETEAEVLEALRALAQG--RTVLLVTH 515
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
267-478 |
1.31e-17 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 81.48 E-value: 1.31e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTI--LNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIW----- 338
Cdd:cd03245 3 IEFRNVSFSYPNQEIpaLDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGlYKPTS--------GSVLLDGTDIRqldpa 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVSPEMHraylknlpaieIVASGLHDSIGLYKRPQPEQMAvcewwMDIFGIAGLKDkpFLQ------------ 406
Cdd:cd03245 75 DLRRNIGYVPQDVT-----------LFYGTLRDNITLGAPLADDERI-----LRAAELAGVTD--FVNkhpngldlqige 136
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 407 ----LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTHYESELpdTITNRI 478
Cdd:cd03245 137 rgrgLSGGQRQAVALARALLNDPPILLLDEPTSAMDMNSEERLKERLRQL--LGDKTLIIITHRPSLL--DLVDRI 208
|
|
| drrA |
TIGR01188 |
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ... |
275-469 |
2.29e-17 |
|
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]
Pssm-ID: 130256 [Multi-domain] Cd Length: 302 Bit Score: 82.44 E-value: 2.29e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSyacdislfGRKRGTGESIW----EIKKHIGyVSP 349
Cdd:TIGR01188 2 VYGDFKAVDGVNFKVREGEVFGFLGPNGAGKTTTIRmLTTLLRPTS--------GTARVAGYDVVreprKVRRSIG-IVP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EMHRAYlKNLPAIE-IVASGlhdsiGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELL 428
Cdd:TIGR01188 73 QYASVD-EDLTGREnLEMMG-----RLYGLPKDEAEERAEELLELFELGEAADRPVGTYSGGMRRRLDIAASLIHQPDVL 146
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2469828120 429 ILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESE 469
Cdd:TIGR01188 147 FLDEPTTGLDPRTRRAIWDYIRAL-KEEGVTILLTTHYMEE 186
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
269-465 |
2.42e-17 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 84.88 E-value: 2.42e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRT--ILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyaCDISLFGRK-RGTGESiwEIKKHI 344
Cdd:PRK11160 341 LNNVSFTYPDQPqpVLKGLSLQIKAGEKVALLGRTGCGKSTLLQLLTrAWDPQQ--GEILLNGQPiADYSEA--ALRQAI 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMH--RAYLK-NLpaiEIVASGLHDS--------IGLYKRPQPEQMAVCewWMdifGIAGLkdkpflQLSSGEQR 413
Cdd:PRK11160 417 SVVSQRVHlfSATLRdNL---LLAAPNASDEalievlqqVGLEKLLEDDKGLNA--WL---GEGGR------QLSGGEQR 482
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 414 LALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkrKDKTMIMVTH 465
Cdd:PRK11160 483 RLGIARALLHDAPLLLLDEPTEGLDAETERQILELLAEHA--QNKTVLMITH 532
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
267-478 |
2.54e-17 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 80.38 E-value: 2.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCadnpqsyacdislfGRKRGTGESIWEIKKHIGY 346
Cdd:cd03301 1 VELENVTKRFGNVTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIA--------------GLEEPTSGRIYIGGRDVTD 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEmHR---------AYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLAL 416
Cdd:cd03301 67 LPPK-DRdiamvfqnyALYPHMTVYDNIAFGLK----LRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQrQRVAL 141
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 417 lARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESElPDTITNRI 478
Cdd:cd03301 142 -GRAIVREPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVE-AMTMADRI 201
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
277-465 |
2.54e-17 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 80.23 E-value: 2.54e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyacdislfgrkrgTGESIWEiKKHIGYVSPEMHRA-- 354
Cdd:cd03231 11 DGRALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPL-------------AGRVLLN-GGPLDFQRDSIARGll 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 355 YLKNLPAIEIVASGLHDSIGLYKRPQPEQmavCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPL 434
Cdd:cd03231 77 YLGHAPGIKTTLSVLENLRFWHADHSDEQ---VEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPT 153
|
170 180 190
....*....|....*....|....*....|.
gi 2469828120 435 HGLDTYNRRRVKKVIEAFCKRkDKTMIMVTH 465
Cdd:cd03231 154 TALDKAGVARFAEAMAGHCAR-GGMVVLTTH 183
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
266-465 |
2.77e-17 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 80.63 E-value: 2.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDR----TILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSyaCDISLFGRK--RGTGESIW 338
Cdd:cd03257 1 LLEVKNLSVSFPTGggsvKALDDVSFSIKKGETLGLVGESGSGKSTLArAILGLLKPTS--GSIIFDGKDllKLSRRLRK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYV--------SPEM------------HRAyLKNLPAIEIVASGLHDSIGLykrpqPEQMavcewwmdifgiag 398
Cdd:cd03257 79 IRRKEIQMVfqdpmsslNPRMtigeqiaeplriHGK-LSKKEARKEAVLLLLVGVGL-----PEEV-------------- 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 399 LKDKPFlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03257 139 LNRYPH-ELSGGQRQRVAIARALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITH 204
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
24-219 |
2.79e-17 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 80.27 E-value: 2.79e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAtqtvyDNVKYIAfrdtygaadanyYYQQRWNAh 103
Cdd:cd03235 18 VSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPLE-----KERKRIG------------YVPQRRSI- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 104 DQDETPDVRE--MLGEI-----------KDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNP 170
Cdd:cd03235 80 DRDFPISVRDvvLMGLYghkglfrrlskADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEP 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 171 FIGLDAPTRELLFSLLERLtKMSSVQIILVLSMLDDIPSFITHVIPVDK 219
Cdd:cd03235 160 FAGVDPKTQEDIYELLREL-RREGMTILVVTHDLGLVLEYFDRVLLLNR 207
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
267-465 |
3.00e-17 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 82.81 E-value: 3.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGR--------KRGtgesi 337
Cdd:COG3839 4 LELENVSKSYGGVEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGlEDPTS--GEILIGGRdvtdlppkDRN----- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 weikkhIGYVS------PEMhRAYlKNLpaieivASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKD-KPfLQLSSG 410
Cdd:COG3839 77 ------IAMVFqsyalyPHM-TVY-ENI------AFPLK----LRKVPKAEIDRRVREAAELLGLEDLLDrKP-KQLSGG 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 411 E-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG3839 138 QrQRVAL-GRALVREPKVFLLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIYVTH 192
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
271-478 |
3.23e-17 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 80.14 E-value: 3.23e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 271 KVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYACDISLFGRKRGTGESIWEIKKHIGYVS 348
Cdd:cd03292 5 NVTKTYpNGTAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKeELPTSGTIRVNGQDVSDLRGRAIPYLRRKIGVVF 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 349 PEMHraYLKNLPAIEIVASGLHDSiglYKRPQPEQMAVCEWwMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELL 428
Cdd:cd03292 85 QDFR--LLPDRNVYENVAFALEVT---GVPPREIRKRVPAA-LELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTIL 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 429 ILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHyESELPDTITNRI 478
Cdd:cd03292 159 IADEPTGNLDPDTTWEIMNLLKKINKA-GTTVVVATH-AKELVDTTRHRV 206
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
22-215 |
3.46e-17 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 80.20 E-value: 3.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIAFrdtygaadanyYYQqrwN 101
Cdd:cd03225 18 DDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKELRRKVGL-----------VFQ---N 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 102 AHDQDETPDVRE---------MLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFI 172
Cdd:cd03225 84 PDDQFFGPTVEEevafglenlGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDILLLDEPTA 163
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 173 GLDAPTRELLFSLLERLTKmSSVQIILVLSMLDDIPSFITHVI 215
Cdd:cd03225 164 GLDPAGRRELLELLKKLKA-EGKTIIIVTHDLDLLLELADRVI 205
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
296-480 |
5.37e-17 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 79.65 E-value: 5.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 296 ALSGENGAGKSTLLSLVCA-DNPqsYACDISLFGRKRGTGESIWEI---KKHIGYVSPEMhrAYLKNLPAIEIVASGLHD 371
Cdd:cd03297 27 GIFGASGAGKSTLLRCIAGlEKP--DGGTIVLNGTVLFDSRKKINLppqQRKIGLVFQQY--ALFPHLNVRENLAFGLKR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 372 SIGLYKRPQPEQMavcewwMDIFGIAGLKDKPFLQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIE 450
Cdd:cd03297 103 KRNREDRISVDEL------LDLLGLDHLLNRYPAQLSGGEkQRVAL-ARALAAQPELLLLDEPFSALDRALRLQLLPELK 175
|
170 180 190
....*....|....*....|....*....|
gi 2469828120 451 AFCKRKDKTMIMVTHYESELpDTITNRIFL 480
Cdd:cd03297 176 QIKKNLNIPVIFVTHDLSEA-EYLADRIVV 204
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
267-465 |
5.38e-17 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 80.23 E-value: 5.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY----DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQsYACDISLFGRKRGTGESIWeIKK 342
Cdd:COG1124 2 LEVRNLSVSYgqggRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERP-WSGEVTFDGRPVTRRRRKA-FRR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYV--SPE-----MHRAYlknlpaiEIVASGLHdsigLYKRPQPEQmAVCEWwMDIFGI-AGLKDKPFLQLSSGE-QR 413
Cdd:COG1124 80 RVQMVfqDPYaslhpRHTVD-------RILAEPLR----IHGLPDREE-RIAEL-LEQVGLpPSFLDRYPHQLSGGQrQR 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 414 LALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1124 147 VAI-ARALILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSH 197
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
272-438 |
6.26e-17 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 80.54 E-value: 6.26e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPqSYACDISLFGRKRGTgesiWeikkhigyvSPE- 350
Cdd:COG4559 7 LSVRLGGRTLLDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELT-PSSGEVRLNGRPLAA----W---------SPWe 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 --MHRAYLK-------NLPAIEIVASGLHDSIGLYKRPQPEQMAVcewwMDIFGIAGLKDKPFLQLSSGEQRLALLARAF 421
Cdd:COG4559 73 laRRRAVLPqhsslafPFTVEEVVALGRAPHGSSAAQDRQIVREA----LALVGLAHLAGRSYQTLSGGEQQRVQLARVL 148
|
170 180
....*....|....*....|....
gi 2469828120 422 V-------KDPELLILDEPLHGLD 438
Cdd:COG4559 149 AqlwepvdGGPRWLFLDEPTSALD 172
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
260-465 |
9.92e-17 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 80.03 E-value: 9.92e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 260 NYDSDEVVKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyaCDISLFGrKRGTGES 336
Cdd:PRK13632 1 IKNKSVMIKVENVSFSYpnSENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLlKPQS--GEIKIDG-ITISKEN 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 337 IWEIKKHIGYVspemhrayLKNlPAIEIVASGLHDSI--GLY-KRPQPEQM-AVCEWWMDIFGIAGLKDKPFLQLSSGE- 411
Cdd:PRK13632 78 LKEIRKKIGII--------FQN-PDNQFIGATVEDDIafGLEnKKVPPKKMkDIIDDLAKKVGMEDYLDKEPQNLSGGQk 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 412 QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13632 149 QRVAI-ASVLALNPEIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITH 201
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
282-469 |
1.16e-16 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 78.95 E-value: 1.16e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSYACDISLFGrkrgTGESIWEIKKHIGYVSPEMhrAYLKNLP 360
Cdd:cd03266 21 VDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAgLLEPDAGFATVDGFD----VVKEPAEARRRLGFVSDST--GLYDRLT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 361 AIEIVA--SGLHdsiGLYKRpqpEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLD 438
Cdd:cd03266 95 ARENLEyfAGLY---GLKGD---ELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGLD 168
|
170 180 190
....*....|....*....|....*....|.
gi 2469828120 439 TYNRRRVKKVIEAFCkRKDKTMIMVTHYESE 469
Cdd:cd03266 169 VMATRALREFIRQLR-ALGKCILFSTHIMQE 198
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
282-479 |
1.31e-16 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 79.02 E-value: 1.31e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFGRKRGTGESIW----------------EI----K 341
Cdd:COG4778 27 LDGVSFSVAAGECVALTGPSGAGKSTLLK--------------CIYGNYLPDSGSILvrhdggwvdlaqasprEIlalrR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVSpemhrAYLKNLP---AIEIVASGLHDSiGlYKRPQPEQMAvcEWWMDIFGIA-GLKDKPFLQLSSGE-QRLAL 416
Cdd:COG4778 93 RTIGYVS-----QFLRVIPrvsALDVVAEPLLER-G-VDREEARARA--RELLARLNLPeRLWDLPPATFSGGEqQRVNI 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 417 lARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAfCKRKDKTMIMVTHYEsELPDTITNRIF 479
Cdd:COG4778 164 -ARGFIADPPLLLLDEPTASLDAANRAVVVELIEE-AKARGTAIIGIFHDE-EVREAVADRVV 223
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
267-465 |
2.15e-16 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 78.35 E-value: 2.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDR---TILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnpQSY----ACDISLFGRKRGTGESIWe 339
Cdd:cd03249 1 IEFKNVSFRYPSRpdvPILKGLSLTIPPGKTVALVGSSGCGKSTVVSLL-----ERFydptSGEILLDGVDIRDLNLRW- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIGYVSPEmhraylknlPAIeiVASGLHDSI--GLYKRPQPEQMAVCEWWMDIFGIAGLKDKpF--------LQLSS 409
Cdd:cd03249 75 LRSQIGLVSQE---------PVL--FDGTIAENIryGKPDATDEEVEEAAKKANIHDFIMSLPDG-YdtlvgergSQLSG 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 410 GE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:cd03249 143 GQkQRIAI-ARALLRNPKILLLDEATSALDAESEKLVQEALDRA--MKGRTTIVIAH 196
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
267-479 |
2.75e-16 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 78.04 E-value: 2.75e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnPQSYacDISLfGRKRGTGESIWEIK--- 341
Cdd:cd03251 1 VEFKNVTFRYpgDGPPVLRDISLDIPAGETVALVGPSGSGKSTLVNLI----PRFY--DVDS-GRILIDGHDVRDYTlas 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 --KHIGYVSPEMHR---------AYLK-NLPAIEIV----ASGLHDSIglykrpqpeqMAVCEWWMDIFGIAGLKdkpfl 405
Cdd:cd03251 74 lrRQIGLVSQDVFLfndtvaeniAYGRpGATREEVEeaarAANAHEFI----------MELPEGYDTVIGERGVK----- 138
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 406 qLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTHYESelpdTITN--RIF 479
Cdd:cd03251 139 -LSGGQrQRIAI-ARALLKDPPILILDEATSALDTESERLVQAALERL--MKNRTTFVIAHRLS----TIENadRIV 207
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
269-465 |
3.12e-16 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 76.58 E-value: 3.12e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYD--DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyaCDISLFGRKRGTGESiwEIKKHIG 345
Cdd:cd03247 3 INNVSFSYPeqEQQVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDlKPQQ--GEITLDGVPVSDLEK--ALSSLIS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSpemHRAYLknlpaieiVASGLHDSIGLykrpqpeqmavcewwmdifgiaglkdkpflQLSSGEQRLALLARAFVKDP 425
Cdd:cd03247 79 VLN---QRPYL--------FDTTLRNNLGR------------------------------RFSGGERQRLALARILLQDA 117
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIeaFCKRKDKTMIMVTH 465
Cdd:cd03247 118 PIVLLDEPTVGLDPITERQLLSLI--FEVLKDKTLIWITH 155
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
268-466 |
4.72e-16 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 77.49 E-value: 4.72e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTIlnELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIweikkhiGY 346
Cdd:COG3840 3 RLDDLTYRYGDFPL--RFDLTIAAGERVAILGPSGAGKSTLLNLIAGfLPPDS--------GRILWNGQDL-------TA 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPE--------------MHRAYLKNlpaieiVASGLHDSIglykRPQPEQMAVCEWWMDIFGIAGLKD-KPFlQLSSGE 411
Cdd:COG3840 66 LPPAerpvsmlfqennlfPHLTVAQN------IGLGLRPGL----KLTAEQRAQVEQALERVGLAGLLDrLPG-QLSGGQ 134
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 412 QRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHY 466
Cdd:COG3840 135 RQRVALARCLVRKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHD 189
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
34-478 |
4.90e-16 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 80.62 E-value: 4.90e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 34 IAIVGPNGGGKSLFVDTLTGKypLREGTLQYDFFPSatqtvYDNV-KYiaFRdtyGAADANYYYQQRWN----AHD-Q-- 105
Cdd:PRK13409 102 TGILGPNGIGKTTAVKILSGE--LIPNLGDYEEEPS-----WDEVlKR--FR---GTELQNYFKKLYNGeikvVHKpQyv 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 106 DETPD-----VREMLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRE 180
Cdd:PRK13409 170 DLIPKvfkgkVRELLKKVDERGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLDIRQRL 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 181 LLFSLLERLTKMSSVQII----LVLSMLDDI-------PS---FITHvipvdkmevfPKVEREA---YLDAF------RD 237
Cdd:PRK13409 250 NVARLIRELAEGKYVLVVehdlAVLDYLADNvhiaygePGaygVVSK----------PKGVRVGineYLKGYlpeenmRI 319
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 238 RDIAVSFDELQKRiidlpydgNNYDSDEVVKLNKVSIRYDDRTiLNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADN 316
Cdd:PRK13409 320 RPEPIEFEERPPR--------DESERETLVEYPDLTKKLGDFS-LEVEGGEIYEGEVIGIVGPNGIGKTTFAKlLAGVLK 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 317 PQSyacdislfgrkrgtGESIWEIKkhIGY----VSPEMH---RAYLKNlpaieiVASGLHDSIglykrpqpeqmavceW 389
Cdd:PRK13409 391 PDE--------------GEVDPELK--ISYkpqyIKPDYDgtvEDLLRS------ITDDLGSSY---------------Y 433
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 390 WMDI---FGIAGLKDKPFLQLSSGE-QRLAlLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13409 434 KSEIikpLQLERLLDKNVKDLSGGElQRVA-IAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRIAEEREATALVVDH 512
|
490
....*....|....*
gi 2469828120 466 --YeseLPDTITNRI 478
Cdd:PRK13409 513 diY---MIDYISDRL 524
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
267-469 |
6.19e-16 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 76.99 E-value: 6.19e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDIsLFGRKRGTGESIWEikKHIGY 346
Cdd:cd03296 3 IEVRNVSKRFGDFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLI-AGLERPDSGTI-LFGGEDATDVPVQE--RNVGF 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSpeMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLALlARAFVKDP 425
Cdd:cd03296 79 VF--QHYALFRHMTVFDNVAFGLRVKPRSERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQrQRVAL-ARALAVEP 155
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:cd03296 156 KVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEE 199
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
263-469 |
7.79e-16 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 78.72 E-value: 7.79e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKST----LLSLVCADNPQSYACDISLFGRKRGTgesiw 338
Cdd:PRK13536 38 STVAIDLAGVSKSYGDKAVVNGLSFTVASGECFGLLGPNGAGKSTiarmILGMTSPDAGKITVLGVPVPARARLA----- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 eiKKHIGYVSP----EMHRAYLKNLpaieIVasglhdsIGLYKRPQPEQM-AVCEWWMDIFGIAGLKDKPFLQLSSGEQR 413
Cdd:PRK13536 113 --RARIGVVPQfdnlDLEFTVRENL----LV-------FGRYFGMSTREIeAVIPSLLEFARLESKADARVSDLSGGMKR 179
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 414 LALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHYESE 469
Cdd:PRK13536 180 RLTLARALINDPQLLILDEPTTGLDPHARHLIWERLRSLLAR-GKTILLTTHFMEE 234
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
267-465 |
8.68e-16 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 77.49 E-value: 8.68e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYD-----DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadN----PQS---YACDISLFGRKrgtG 334
Cdd:TIGR04521 1 IKLKNVSYIYQpgtpfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHL---NgllkPTSgtvTIDGRDITAKK---K 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 335 ESIWEIKKHIGYV--SPEmHR----------AY-LKNLpaieivasglhdsiGLykrpqPEQMAVC--EWWMDIFGI-AG 398
Cdd:TIGR04521 75 KKLKDLRKKVGLVfqFPE-HQlfeetvykdiAFgPKNL--------------GL-----SEEEAEErvKEALELVGLdEE 134
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 399 LKDK-PFlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:TIGR04521 135 YLERsPF-ELSGGQMRRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTH 201
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
262-470 |
8.99e-16 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 76.29 E-value: 8.99e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCadnpqsyacdiSLFGRKRGTgesIWEIK 341
Cdd:PRK10247 3 ENSPLLQLQNVGYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVA-----------SLISPTSGT---LLFEG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVSPEMHR---AYLKNLPAieIVASGLHDSIGL-----YKRPQPEQMAVcewWMDIFGIA-GLKDKPFLQLSSGE- 411
Cdd:PRK10247 69 EDISTLKPEIYRqqvSYCAQTPT--LFGDTVYDNLIFpwqirNQQPDPAIFLD---DLERFALPdTILTKNIAELSGGEk 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 412 QRLALLaRAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESEL 470
Cdd:PRK10247 144 QRISLI-RNLQFMPKVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEI 201
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
275-466 |
9.15e-16 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 76.60 E-value: 9.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyacdislfGRKRGTGESIWEIK-KHIGYVSPEM- 351
Cdd:cd03267 30 KYREVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLlQPTS--------GEVRVAGLVPWKRRkKFLRRIGVVFg 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 HRAYLK-NLPAIEIVAsgLHDSIglYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLIL 430
Cdd:cd03267 102 QKTQLWwDLPVIDSFY--LLAAI--YDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFL 177
|
170 180 190
....*....|....*....|....*....|....*.
gi 2469828120 431 DEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHY 466
Cdd:cd03267 178 DEPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHY 213
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
18-483 |
1.47e-15 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 79.08 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 18 VRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTG--KYPLREGTLQY------------------------------- 64
Cdd:TIGR03269 13 KEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdQYEPTSGRIIYhvalcekcgyverpskvgepcpvcggtlepe 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 65 --DFFPSATQTVYDNVKYIAFrdtygaadanyyYQQRWNAHDQDET--PDVREMLGEIK---DEQLKN--ELFELFRIEP 135
Cdd:TIGR03269 93 evDFWNLSDKLRRRIRKRIAI------------MLQRTFALYGDDTvlDNVLEALEEIGyegKEAVGRavDLIEMVQLSH 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 136 LLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVI 215
Cdd:TIGR03269 161 RITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 216 PVDKMEVFPKVEREAYLDAFRDrdiavSFDELQKriidlpyDGNNYDSDEVVKLNKVSIRY--DDRTILNELD---WTVR 290
Cdd:TIGR03269 241 WLENGEIKEEGTPDEVVAVFME-----GVSEVEK-------ECEVEVGEPIIKVRNVSKRYisVDRGVVKAVDnvsLEVK 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 291 RGEKWALSGENGAGKSTLLSLVCADNPQSYACDISLFG------RKRGTGESiWEIKKHIGYVSPEM----HRAYLKNLP 360
Cdd:TIGR03269 309 EGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRVGdewvdmTKPGPDGR-GRAKRYIGILHQEYdlypHRTVLDNLT 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 361 aieivasglhDSIGLykrPQPEQMAVCE--WWMDIFGIAGLKDKPFL-----QLSSGEQRLALLARAFVKDPELLILDEP 433
Cdd:TIGR03269 388 ----------EAIGL---ELPDELARMKavITLKMVGFDEEKAEEILdkypdELSEGERHRVALAQVLIKEPRIVILDEP 454
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 434 LHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHyESELPDTITNRIFLKRN 483
Cdd:TIGR03269 455 TGTMDPITKVDVTHSILKAREEMEQTFIIVSH-DMDFVLDVCDRAALMRD 503
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
272-465 |
1.93e-15 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 75.29 E-value: 1.93e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAC----DISLFGRK-RGTGESIWEIKKHIGY 346
Cdd:cd03260 6 LNVYYGDKHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGApdegEVLLDGKDiYDLDVDVLELRRRVGM 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VspeMHRAYLKNLPAIEIVASG--LHDSiglykRPQPEQMAVCEWWMDIfgiAGLKDK-----PFLQLSSGE-QRLALlA 418
Cdd:cd03260 86 V---FQKPNPFPGSIYDNVAYGlrLHGI-----KLKEELDERVEEALRK---AALWDEvkdrlHALGLSGGQqQRLCL-A 153
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:cd03260 154 RALANEPEVLLLDEPTSALDPISTAKIEELIAEL--KKEYTIVIVTH 198
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
265-465 |
2.09e-15 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 74.87 E-value: 2.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRK-RGTGESIWEIKK 342
Cdd:cd03262 2 EIKNLHK---SFGDFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLlEEPDS--GTIIIDGLKlTDDKKNINELRQ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSpeMHRAYLKNLPAIEIVASGLhdsIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLAlLARAF 421
Cdd:cd03262 77 KVGMVF--QQFNLFPHLTVLENITLAP---IKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQqQRVA-IARAL 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 422 VKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTH 465
Cdd:cd03262 151 AMNPKVMLFDEPTSALDPELVGEVLDVMKDLAEEG-MTMVVVTH 193
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
19-188 |
3.21e-15 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 74.44 E-value: 3.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQtvydnvkyiafRDTYgAADANYYYQQ 98
Cdd:COG4133 16 LLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDA-----------REDY-RRRLAYLGHA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 99 rwNAHDQDETpdVREML-------GEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPF 171
Cdd:COG4133 84 --DGLKPELT--VRENLrfwaalyGLRADREAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAPLWLLDEPF 159
|
170
....*....|....*..
gi 2469828120 172 IGLDAPTRELLFSLLER 188
Cdd:COG4133 160 TALDAAGVALLAELIAA 176
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
267-465 |
3.29e-15 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 75.03 E-value: 3.29e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadN----PQSyacdislfGRKRGTGESIWEI- 340
Cdd:cd03295 1 IEFENVTKRYgGGKKAVNNLNLEIAKGEFLVLIGPSGSGKTTTMKMI---NrliePTS--------GEIFIDGEDIREQd 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 ----KKHIGYVSPEM----HRAYLKNlpaIEIVASGLHdsiglYKRPQPEQMAvcewwMDIFGIAGLKDKPFL-----QL 407
Cdd:cd03295 70 pvelRRKIGYVIQQIglfpHMTVEEN---IALVPKLLK-----WPKEKIRERA-----DELLALVGLDPAEFAdryphEL 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 408 SSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03295 137 SGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTH 194
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
267-465 |
3.40e-15 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 77.19 E-value: 3.40e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyACDISLfgrKRGTGE----------- 335
Cdd:PRK09536 4 IDVSDLSVEFGDTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLR----------AINGTL---TPTAGTvlvagddveal 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 SIWEIKKHIGYVSPEMHRAYlkNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:PRK09536 71 SARAASRRVASVPQDTSLSF--EFDVRQVVEMGRTPHRSRFDTWTETDRAAVERAMERTGVAQFADRPVTSLSGGERQRV 148
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTH 465
Cdd:PRK09536 149 LLARALAQATPVLLLDEPTASLDINHQVRTLELVRRLVD-DGKTAVAAIH 197
|
|
| cbiO |
TIGR01166 |
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ... |
277-465 |
3.95e-15 |
|
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 130234 [Multi-domain] Cd Length: 190 Bit Score: 73.61 E-value: 3.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSYAcdISLFGRKRGTG-ESIWEIKKHIGYV--SPEMH 352
Cdd:TIGR01166 3 GGPEVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLlRPQSGA--VLIDGEPLDYSrKGLLERRQRVGLVfqDPDDQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 353 RAYlknlPAI-EIVASGLHDsIGLykrPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILD 431
Cdd:TIGR01166 81 LFA----ADVdQDVAFGPLN-LGL---SEAEVERRVREALTAVGASGLRERPTHCLSGGEKKRVAIAGAVAMRPDVLLLD 152
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 432 EPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:TIGR01166 153 EPTAGLDPAGREQMLAILRRL-RAEGMTVVISTH 185
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
267-465 |
4.06e-15 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 75.05 E-value: 4.06e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADN-PQSyacdislfGRKRGTGESIWeikkhiG 345
Cdd:PRK11231 3 LRTENLTVGYGTKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLtPQS--------GTVFLGDKPIS------M 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPEMHRaYLKNLPAI----------EIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:PRK11231 69 LSSRQLAR-RLALLPQHhltpegitvrELVAYGRSPWLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRA 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK11231 148 FLAMVLAQDTPVVLLDEPTTYLDINHQVELMRLMREL-NTQGKTVVTVLH 196
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
22-215 |
5.41e-15 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 72.28 E-value: 5.41e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPsatqtvydnvkyiafrdtygaadanyyyqqrwn 101
Cdd:cd00267 16 DNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKD--------------------------------- 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 102 ahdqdetpdvremLGEIKDEQLKNELFELFRieplldkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTREL 181
Cdd:cd00267 63 -------------IAKLPLEELRRRIGYVPQ-----------LSGGQRQRVALARALLLNPDLLLLDEPTSGLDPASRER 118
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 182 LFSLLERLTKmSSVQIILVLSMLDDIPSFITHVI 215
Cdd:cd00267 119 LLELLRELAE-EGRTVIIVTHDPELAELAADRVI 151
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
27-438 |
5.57e-15 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 77.30 E-value: 5.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQY--DFFPSATQ---------TVYDnvkYIAfrdtYGAADA--- 92
Cdd:PRK11147 25 HIEDNERVCLVGRNGAGKSTLMKILNGEVLLDDGRIIYeqDLIVARLQqdpprnvegTVYD---FVA----EGIEEQaey 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 93 --NYYYQQRWNAHDQDETpDVREM--LGEIKDE----QLK---NELFELFRIEPllDKKIILLSSGELRKFQLTKTLLTA 161
Cdd:PRK11147 98 lkRYHDISHLVETDPSEK-NLNELakLQEQLDHhnlwQLEnriNEVLAQLGLDP--DAALSSLSGGWLRKAALGRALVSN 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 162 PRVLIMDNPFIGLDAPTREllfsLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVD--KMEVFPKvEREAYLDAfrdRD 239
Cdd:PRK11147 175 PDVLLLDEPTNHLDIETIE----WLEGFLKTFQGSIIFISHDRSFIRNMATRIVDLDrgKLVSYPG-NYDQYLLE---KE 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 240 IAVSFDELQKRIID----------------------------------------------LPYDGNNYDSDEVVKLNKVS 273
Cdd:PRK11147 247 EALRVEELQNAEFDrklaqeevwirqgikarrtrnegrvralkalrrerserrevmgtakMQVEEASRSGKIVFEMENVN 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 274 IRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyacdislfGR-KRGTgesiweiKKHIGYVspEM 351
Cdd:PRK11147 327 YQIDGKQLVKDFSAQVQRGDKIALIGPNGCGKTTLLKLMLGQlQADS--------GRiHCGT-------KLEVAYF--DQ 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 HRAYLKnlP---AIEIVASGLHD-SIGLYKRpqpeqmavcewwmDIFGIagLKD---------KPFLQLSSGEQRLALLA 418
Cdd:PRK11147 390 HRAELD--PektVMDNLAEGKQEvMVNGRPR-------------HVLGY--LQDflfhpkramTPVKALSGGERNRLLLA 452
|
490 500
....*....|....*....|
gi 2469828120 419 RAFVKDPELLILDEPLHGLD 438
Cdd:PRK11147 453 RLFLKPSNLLILDEPTNDLD 472
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
267-475 |
6.00e-15 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 72.46 E-value: 6.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLvcadnpqsyacdisLFG-RKRGTGESIWEIKKhIG 345
Cdd:cd03216 1 LELRGITKRFGGVKALDGVSLSVRRGEVHALLGENGAGKSTLMKI--------------LSGlYKPDSGEILVDGKE-VS 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSP-EMHRAylknlpAIEIVasglHdsiglykrpqpeqmavcewwmdifgiaglkdkpflQLSSGEQRLALLARAFVKD 424
Cdd:cd03216 66 FASPrDARRA------GIAMV----Y-----------------------------------QLSVGERQMVEIARALARN 100
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 425 PELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELP---DTIT 475
Cdd:cd03216 101 ARLLILDEPTAALTPAEVERLFKVIRRL-RAQGVAVIFISHRLDEVFeiaDRVT 153
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
265-465 |
8.57e-15 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 75.57 E-value: 8.57e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADNPQsyacdISLFGRkrgtgesIWEI 340
Cdd:COG1118 4 EVRNISK---RFGSFTLLDDVSLEIASGELVALLGPSGSGKTTLLRiiagLETPDSGR-----IVLNGR-------DLFT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 -----KKHIGYVSpeMHRAYLKNLPAIEIVASGLHDSiglyKRPQPEQMAVCEWWMDIFGIAGLKD-KPFlQLSSGE-QR 413
Cdd:COG1118 69 nlpprERRVGFVF--QHYALFPHMTVAENIAFGLRVR----PPSKAEIRARVEELLELVQLEGLADrYPS-QLSGGQrQR 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 414 LALlARAFVKDPELLILDEPLHGLDTYNR---RRV-KKVIEAFckrkDKTMIMVTH 465
Cdd:COG1118 142 VAL-ARALAVEPEVLLLDEPFGALDAKVRkelRRWlRRLHDEL----GGTTVFVTH 192
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
264-465 |
1.28e-14 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 74.11 E-value: 1.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYDDRT-ILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSYACdisLFGRK--RGTGESIWE 339
Cdd:PRK13636 3 DYILKVEELNYNYSDGThALKGININIKKGEVTAILGGNGAGKSTLFqNLNGILKPSSGRI---LFDGKpiDYSRKGLMK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIGYVSPEmhraylknlPAIEIVASGLHDSIGL----YKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:PRK13636 80 LRESVGMVFQD---------PDNQLFSASVYQDVSFgavnLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRV 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13636 151 AIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATH 200
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
262-485 |
1.33e-14 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 73.09 E-value: 1.33e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnpqsyacdISLFGRKRGT----GESI 337
Cdd:COG1127 1 MSEPMIEVRNLTKSFGDRVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLI-----------IGLLRPDSGEilvdGQDI 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 W--------EIKKHIGYV--------S---------P-EMHRaylkNLPAIEIvasglhDSIGLYKrpqpeqmavcewwM 391
Cdd:COG1127 70 TglsekelyELRRRIGMLfqggalfdSltvfenvafPlREHT----DLSEAEI------RELVLEK-------------L 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 392 DIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHyesELP 471
Cdd:COG1127 127 ELVGLPGAADKMPSELSGGMRKRVALARALALDPEILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTH---DLD 203
|
250
....*....|....*..
gi 2469828120 472 D--TITNRI-FLKRNQV 485
Cdd:COG1127 204 SafAIADRVaVLADGKI 220
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
282-465 |
1.35e-14 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 72.88 E-value: 1.35e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYAcdISLFGRKrgtgesiweikkhIGYVSPE-----MHRAY 355
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGlAQPTSGG--VILEGKQ-------------ITEPGPDrmvvfQNYSL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 356 LKNLPAIEIVASGLhDSIgLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSG-EQRLALlARAFVKDPELLILDEPL 434
Cdd:TIGR01184 66 LPWLTVRENIALAV-DRV-LPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGmKQRVAI-ARALSIRPKVLLLDEPF 142
|
170 180 190
....*....|....*....|....*....|.
gi 2469828120 435 HGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:TIGR01184 143 GALDALTRGNLQEELMQIWEEHRVTVLMVTH 173
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
272-465 |
1.93e-14 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 72.01 E-value: 1.93e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLFGRKRGTGESIWEikKHIGYVSpem 351
Cdd:TIGR01189 6 LACSRGERMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRIL-AGLLRPDSGEVRWNGTPLAEQRDEPH--ENILYLG--- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 HRAYLKN-LPAIEivasGLHdsigLYKR-PQPEQMAVCEWwMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLI 429
Cdd:TIGR01189 80 HLPGLKPeLSALE----NLH----FWAAiHGGAQRTIEDA-LAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWI 150
|
170 180 190
....*....|....*....|....*....|....*.
gi 2469828120 430 LDEPLHGLDTYNRRRVKKVIEAFCKRKDKTmIMVTH 465
Cdd:TIGR01189 151 LDEPTTALDKAGVALLAGLLRAHLARGGIV-LLTTH 185
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
278-480 |
2.06e-14 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 72.30 E-value: 2.06e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 278 DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC--ADNPQSYACDISLFGRKRgtgeSIWEIKKHIGYVspEMHRAY 355
Cdd:cd03234 19 YARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISgrVEGGGTTSGQILFNGQPR----KPDQFQKCVAYV--RQDDIL 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 356 LKNLPAIEIVASGLHDSIGLYKR-PQPEQMAVCEWWMDIfGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPL 434
Cdd:cd03234 93 LPGLTVRETLTYTAILRLPRKSSdAIRKKRVEDVLLRDL-ALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPT 171
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 435 HGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHY-ESELPDTITNRIFL 480
Cdd:cd03234 172 SGLDSFTALNLVSTLSQLARR-NRIVILTIHQpRSDLFRLFDRILLL 217
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
263-474 |
3.28e-14 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 72.91 E-value: 3.28e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDD--RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-----DNPQSyacDISLFGRKRgTGE 335
Cdd:PRK13640 2 KDNIVEFKHVSFTYPDskKPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGlllpdDNPNS---KITVDGITL-TAK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 SIWEIKKHIGYVspemhrayLKNlPAIEIVASGLHDSI--GLYKR--PQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE 411
Cdd:PRK13640 78 TVWDIREKVGIV--------FQN-PDNQFVGATVGDDVafGLENRavPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQ 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 412 -QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH--YESELPDTI 474
Cdd:PRK13640 149 kQRVAI-AGILAVEPKIIILDESTSMLDPAGKEQILKLIRKLKKKNNLTVISITHdiDEANMADQV 213
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
22-215 |
4.26e-14 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 71.66 E-value: 4.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQ-------------------TVYDNVKyia 82
Cdd:COG1121 23 EDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPPRRArrrigyvpqraevdwdfpiTVRDVVL--- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 83 frdtygaadANYYYQQRW----NAHDQDEtpdVREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQLTKTL 158
Cdd:COG1121 100 ---------MGRYGRRGLfrrpSRADREA---VDEAL-------------ERVGLEDLADRPIGELSGGQQQRVLLARAL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 159 LTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK--MSsvqIILVLSMLDDIPSFITHVI 215
Cdd:COG1121 155 AQDPDLLLLDEPFAGVDAATEEALYELLRELRRegKT---ILVVTHDLGAVREYFDRVL 210
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
267-465 |
4.38e-14 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 72.38 E-value: 4.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlvCADNPQSYACDISLFGRKRGTGESIWEIKKHIGY 346
Cdd:PRK14258 8 IKVNNLSFYYDTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLK--CLNRMNELESEVRVEGRVEFFNQNIYERRVNLNR 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEMHRAYLK-NLPAIEI---VASGLHdSIGLykRPQPEQMAVCEwwmdifgiAGLKD------------KPFLQLSSG 410
Cdd:PRK14258 86 LRRQVSMVHPKpNLFPMSVydnVAYGVK-IVGW--RPKLEIDDIVE--------SALKDadlwdeikhkihKSALDLSGG 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 411 EQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK14258 155 QQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSH 209
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
275-485 |
4.64e-14 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 71.41 E-value: 4.64e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyacdislfGRKRGTGESIWEIkkhigyvspEMHR 353
Cdd:cd03220 31 EVGEFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAgIYPPDS--------GTVTVRGRVSSLL---------GLGG 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 354 AYLKNLPAIE-IVASGLhdsigLYKRPQPEQMAVCEwwmDIFGIAGLK---DKPFLQLSSGEQ-RLAL-LARAFvkDPEL 427
Cdd:cd03220 94 GFNPELTGREnIYLNGR-----LLGLSRKEIDEKID---EIIEFSELGdfiDLPVKTYSSGMKaRLAFaIATAL--EPDI 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 428 LILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:cd03220 164 LLIDEVLAVGDAAFQEKCQRRLRELLK-QGKTVILVSHDPSSIKRLCDRALVLEKGKI 220
|
|
| tungstate_WtpC |
NF040840 |
tungstate ABC transporter ATP-binding protein WtpC; |
282-465 |
4.75e-14 |
|
tungstate ABC transporter ATP-binding protein WtpC;
Pssm-ID: 468779 [Multi-domain] Cd Length: 347 Bit Score: 73.19 E-value: 4.75e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWEI---KKHIGYVsPEMHrAYLK 357
Cdd:NF040840 16 LRDISLEVKEGEYFIILGPSGAGKTVLLELIAGiWPPDS--------GKIYLDGKDITNLppeKRGIAYV-YQNY-MLFP 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 358 NLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGL 437
Cdd:NF040840 86 HKTVFENIAFGLK----LRKVPKEEIERKVKEIMELLGISHLLHRKPRTLSGGEQQRVALARALIIEPKLLLLDEPLSAL 161
|
170 180
....*....|....*....|....*...
gi 2469828120 438 DTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:NF040840 162 DVQTRDELIREMKRWHREFGFTAIHVTH 189
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
268-480 |
5.09e-14 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 70.63 E-value: 5.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLlSLVCADNPQSYACDislfGRKRGTGESIweikkhigyv 347
Cdd:cd03217 2 EIKDLHVSVGGKEILKGVNLTIKKGEVHALMGPNGSGKSTL-AKTIMGHPKYEVTE----GEILFKGEDI---------- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 spemhraylKNLPAIEIVASGlhdsIGL-YKRPqPEqmavcewwmdifgIAGLKDKPFLQ-----LSSGEQRLALLARAF 421
Cdd:cd03217 67 ---------TDLPPEERARLG----IFLaFQYP-PE-------------IPGVKNADFLRyvnegFSGGEKKRNEILQLL 119
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 422 VKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELPDTITNRIFL 480
Cdd:cd03217 120 LLEPDLAILDEPDSGLDIDALRLVAEVINKL-REEGKSVLIITHYQRLLDYIKPDRVHV 177
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
272-465 |
6.45e-14 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 69.55 E-value: 6.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDD--RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSYAC-----DISLFGRKrgtgesiwEIKKH 343
Cdd:cd03246 6 VSFRYPGaePPVLRNVSFSIEPGESLAIIGPSGSGKSTLARLILgLLRPTSGRVrldgaDISQWDPN--------ELGDH 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSPEmhraylknlpaIEIVASGLHDSIglykrpqpeqmavcewwmdifgiaglkdkpflqLSSGE-QRLaLLARAFV 422
Cdd:cd03246 78 VGYLPQD-----------DELFSGSIAENI---------------------------------LSGGQrQRL-GLARALY 112
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:cd03246 113 GNPRILVLDEPNSHLDVEGERALNQAIAAL-KAAGATRIVIAH 154
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
268-465 |
6.86e-14 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 71.43 E-value: 6.86e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYD----DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGR-------KRGTges 336
Cdd:COG4525 5 TVRHVSVRYPgggqPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPS-SGEITLDGVpvtgpgaDRGV--- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 337 iwEIKKHigyvspemhrAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSG-EQRLA 415
Cdd:COG4525 81 --VFQKD----------ALLPWLNVLDNVAFGLR----LRGVPKAERRARAEELLALVGLADFARRRIWQLSGGmRQRVG 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG4525 145 I-ARALAADPRFLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITH 193
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
274-480 |
8.14e-14 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 70.22 E-value: 8.14e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 274 IRyDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNpQSYACDISLFGRKrgtgesiweikkhIGYVSPEMHR 353
Cdd:PRK13538 10 ER-DERILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLA-RPDAGEVLWQGEP-------------IRRQRDEYHQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 354 --AYLKNLPAIEIVASG---LHDSIGLYKRPQPEQMAVCewwMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELL 428
Cdd:PRK13538 75 dlLYLGHQPGIKTELTAlenLRFYQRLHGPGDDEALWEA---LAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLW 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 429 ILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHYESELPDTITNRIFL 480
Cdd:PRK13538 152 ILDEPFTAIDKQGVARLEALLAQHAEQ-GGMVILTTHQDLPVASDKVRKLRL 202
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
269-469 |
9.59e-14 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 71.25 E-value: 9.59e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWEIKKHIGYV 347
Cdd:PRK11247 15 LNAVSKRYGERTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGlETPSA--------GELLAGTAPLAEAREDTRLM 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SPEmhrAYLknLP---AIEIVASGLH-----------DSIGLYKRPQpeqmavcEWwmdifgiaglkdkPfLQLSSGE-Q 412
Cdd:PRK11247 87 FQD---ARL--LPwkkVIDNVGLGLKgqwrdaalqalAAVGLADRAN-------EW-------------P-AALSGGQkQ 140
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 413 RLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:PRK11247 141 RVAL-ARALIHRPGLLLLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSE 196
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
265-485 |
1.10e-13 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 70.93 E-value: 1.10e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQS---YACDISLFGRKRGTGES--IW 338
Cdd:PRK11264 5 EVKNLVK---KFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLrCINLLEQPEAgtiRVGDITIDTARSLSQQKglIR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVSPEM----HRAYLKNLpaIE---IVAsglhdsiglyKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE 411
Cdd:PRK11264 82 QLRQHVGFVFQNFnlfpHRTVLENI--IEgpvIVK----------GEPKEEATARARELLAKVGLAGKETSYPRRLSGGQ 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 412 QRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:PRK11264 150 QQRVAIARALAMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEK-RTMVIVTHEMSFARDVADRAIFMDQGRI 222
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
282-483 |
1.11e-13 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 70.44 E-value: 1.11e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWE---IKKHIGYVsPEMHrAYLK 357
Cdd:cd03299 15 LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGfIKPDS--------GKILLNGKDITNlppEKRDISYV-PQNY-ALFP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 358 NLPAIEIVASGLhdSIGLYKRPQPE----QMAvcewwmDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEP 433
Cdd:cd03299 85 HMTVYKNIAYGL--KKRKVDKKEIErkvlEIA------EMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKILLLDEP 156
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 434 LHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPdTITNRIFLKRN 483
Cdd:cd03299 157 FSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAW-ALADKVAIMLN 205
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
22-171 |
1.43e-13 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 68.06 E-value: 1.43e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTvydnvkYIAFRDTYGaadanYYYQQRW- 100
Cdd:pfam00005 2 KNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQDLTDDE------RKSLRKEIG-----YVFQDPQl 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 101 -----NAHDQDETPDVREMLGEIKDEQLKnELFELFRIEPLLDKKIIL----LSSGELRKFQLTKTLLTAPRVLIMDNPF 171
Cdd:pfam00005 71 fprltVRENLRLGLLLKGLSKREKDARAE-EALEKLGLGDLADRPVGErpgtLSGGQRQRVAIARALLTKPKLLLLDEPT 149
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
263-469 |
1.63e-13 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 70.99 E-value: 1.63e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKST----LLSLVCADNPQSYACDISLFGRKRgtgesiw 338
Cdd:PRK13537 4 SVAPIDFRNVEKRYGDKLVVDGLSFHVQRGECFGLLGPNGAGKTTtlrmLLGLTHPDAGSISLCGEPVPSRAR------- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVsPEmhrayLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLA 418
Cdd:PRK13537 77 HARQRVGVV-PQ-----FDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLA 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHYESE 469
Cdd:PRK13537 151 RALVNDPDVLVLDEPTTGLDPQARHLMWERLRSLLAR-GKTILLTTHFMEE 200
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
268-463 |
1.83e-13 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 69.39 E-value: 1.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL----SLVcadnpQSYACDISLFGRKRgTGESIWEIKKH 343
Cdd:cd03224 2 EVENLNAGYGKSQILFGVSLTVPEGEIVALLGRNGAGKTTLLktimGLL-----PPRSGSIRFDGRDI-TGLPPHERARA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 -IGYVsPEmHRAYLKNLPaieiVASGLHdsIGLYKRPQPEQMAVCEWWMDIFGIagLKDK---PFLQLSSGEQRLALLAR 419
Cdd:cd03224 76 gIGYV-PE-GRRIFPELT----VEENLL--LGAYARRRAKRKARLERVYELFPR--LKERrkqLAGTLSGGEQQMLAIAR 145
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 420 AFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMV 463
Cdd:cd03224 146 ALMSRPKLLLLDEPSEGLAPKIVEEIFEAIREL-RDEGVTILLV 188
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
267-465 |
1.91e-13 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 70.11 E-value: 1.91e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLvcadnpqsyacdIS-LFGRKRGT----GESIWEIK 341
Cdd:COG4604 2 IEIKNVSKRYGGKVVLDDVSLTIPKGGITALIGPNGAGKSTLLSM------------ISrLLPPDSGEvlvdGLDVATTP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 khigyvSPEMHR--AYLKNLPAI-------EIVASGL--HdSIGlykRPQPEQMAVCEWWMDIFGIAGLKDKpFL-QLSS 409
Cdd:COG4604 70 ------SRELAKrlAILRQENHInsrltvrELVAFGRfpY-SKG---RLTAEDREIIDEAIAYLDLEDLADR-YLdELSG 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 410 GEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG4604 139 GQRQRAFIAMVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLH 194
|
|
| heterocyst_DevA |
TIGR02982 |
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly ... |
279-479 |
1.94e-13 |
|
ABC exporter ATP-binding subunit, DevA family; Members of this protein family are found mostly in the Cyanobacteria, but also in the Planctomycetes. Cyanobacterial examples are involved in heterocyst formation, by which some fraction of members of the colony undergo a developmental change and become capable of nitrogen fixation. The DevBCA proteins are thought export of either heterocyst-specific glycolipids or an enzyme essential for formation of the laminated layer found in heterocysts.
Pssm-ID: 274374 [Multi-domain] Cd Length: 220 Bit Score: 69.28 E-value: 1.94e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLSLV-CADNPQSyaCDISLFGR--KRGTGESIWEIKKHIGYVSpeMHRAY 355
Cdd:TIGR02982 18 KQVLFDINLEINPGEIVILTGPSGSGKTTLLTLIgGLRSVQE--GSLKVLGQelHGASKKQLVQLRRRIGYIF--QAHNL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 356 LKNLPAIEIVASG--LHDSIGlykrpQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLALlARAFVKDPELLILDE 432
Cdd:TIGR02982 94 LGFLTARQNVQMAleLQPNLS-----YQEARERARAMLEAVGLGDHLNYYPHNLSGGQkQRVAI-ARALVHHPKLVLADE 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 433 PLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHyeselpdtiTNRIF 479
Cdd:TIGR02982 168 PTAALDSKSGRDVVELMQKLAKEQGCTILMVTH---------DNRIL 205
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
262-469 |
2.04e-13 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 71.29 E-value: 2.04e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNP----------------------- 317
Cdd:PRK11432 2 TQKNFVVLKNITKRFGSNTVIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGlEKPtegqifidgedvthrsiqqrdic 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 318 ---QSYAcdisLFGRKrgtgeSIWEikkHIGYvspemhraylknlpaieivasGLHdsigLYKRPQPEQMAVCEWWMDIF 394
Cdd:PRK11432 82 mvfQSYA----LFPHM-----SLGE---NVGY---------------------GLK----MLGVPKEERKQRVKEALELV 124
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 395 GIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:PRK11432 125 DLAGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSE 199
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
266-465 |
2.07e-13 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 70.14 E-value: 2.07e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnpqsyacdISLFGRKRGTGESiwEIKKHIG 345
Cdd:PRK09544 4 LVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVV-----------LGLVAPDEGVIKR--NGKLRIG 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPEMH---------RAYLKNLPAIEivasgLHDSIGLYKRPQPEQmavcewwmdifgiagLKDKPFLQLSSGEQRLAL 416
Cdd:PRK09544 71 YVPQKLYldttlpltvNRFLRLRPGTK-----KEDILPALKRVQAGH---------------LIDAPMQKLSGGETQRVL 130
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 417 LARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK09544 131 LARALLNRPQLLVLDEPTQGVDVNGQVALYDLIDQLRRELDCAVLMVSH 179
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
259-465 |
2.59e-13 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 69.82 E-value: 2.59e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 259 NNYDSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRKRGTgesiW 338
Cdd:PRK10575 4 YTNHSDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPS-EGEILLDAQPLES----W 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVspemhrAYL-KNLPAI------EIVASG---LHDSIGLYKRPQPEQMAvcewwmDIFGIAGLkdKPFLQ-- 406
Cdd:PRK10575 79 SSKAFARKV------AYLpQQLPAAegmtvrELVAIGrypWHGALGRFGAADREKVE------EAISLVGL--KPLAHrl 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 407 ---LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10575 145 vdsLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLH 206
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
266-465 |
4.67e-13 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 68.58 E-value: 4.67e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRK-RGTGESIWEIKKHI 344
Cdd:PRK09493 1 MIEFKNVSKHFGPTQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEIT-SGDLIVDGLKvNDPKVDERLIRQEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMHraYLKNLPAIEIVASGLHDSIGLyKRPQPEQMAvcewwMDIFGIAGLKDK----PfLQLSSGEQRLALLARA 420
Cdd:PRK09493 80 GMVFQQFY--LFPHLTALENVMFGPLRVRGA-SKEEAEKQA-----RELLAKVGLAERahhyP-SELSGGQQQRVAIARA 150
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTH 465
Cdd:PRK09493 151 LAVKPKLMLFDEPTSALDPELRHEVLKVMQDLAE-EGMTMVIVTH 194
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
22-191 |
7.21e-13 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 68.17 E-value: 7.21e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQ---------------------TVYDNVKY 80
Cdd:COG1131 17 DGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDpaevrrrigyvpqepalypdlTVRENLRF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 81 IAfrDTYGaadanyyyqqrwnahdqdetpdvremLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLT 160
Cdd:COG1131 97 FA--RLYG--------------------------LPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLH 148
|
170 180 190
....*....|....*....|....*....|.
gi 2469828120 161 APRVLIMDNPFIGLDAPTRELLFSLLERLTK 191
Cdd:COG1131 149 DPELLILDEPTSGLDPEARRELWELLRELAA 179
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-478 |
7.86e-13 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 70.58 E-value: 7.86e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 1 MSQNTFSMAGGVARNPLVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTL-----QYDFFPS--ATQ- 72
Cdd:PRK09700 1 MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTItinniNYNKLDHklAAQl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 73 ---------------TVYDNVkYIAFRDTYGAADANYYyqqrwnahdqdetpDVREMlgeikdEQLKNELFELFRIEPLL 137
Cdd:PRK09700 81 gigiiyqelsvidelTVLENL-YIGRHLTKKVCGVNII--------------DWREM------RVRAAMMLLRVGLKVDL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 138 DKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK--MSSVQIILVLSMLDDIPSFIThvI 215
Cdd:PRK09700 140 DEKVANLSISHKQMLEIAKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKegTAIVYISHKLAEIRRICDRYT--V 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 216 PVDKMEVFPKVEREAYLDafrdrDIaVSF---DELQKRIIDLPYDGNNYDSDEVVKLNKVSIRydDRTILNELDWTVRRG 292
Cdd:PRK09700 218 MKDGSSVCSGMVSDVSND-----DI-VRLmvgRELQNRFNAMKENVSNLAHETVFEVRNVTSR--DRKKVRDISFSVCRG 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 293 EKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGRKRGTGESIWEIKKHIGYVSpEMHR--AYLKNLPAIEIVA---- 366
Cdd:PRK09700 290 EILGFAGLVGSGRTELMNCLFGVDKRAGG-EIRLNGKDISPRSPLDAVKKGMAYIT-ESRRdnGFFPNFSIAQNMAisrs 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 367 ---SGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLkDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRR 443
Cdd:PRK09700 368 lkdGGYKGAMGLFHEVDEQRTAENQRELLALKCHSV-NQNITELSGGNQQKVLISKWLCCCPEVIIFDEPTRGIDVGAKA 446
|
490 500 510
....*....|....*....|....*....|....*..
gi 2469828120 444 RVKKVIEAFCKrKDKTMIMVThyeSELPDTIT--NRI 478
Cdd:PRK09700 447 EIYKVMRQLAD-DGKVILMVS---SELPEIITvcDRI 479
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
17-219 |
7.96e-13 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 68.13 E-value: 7.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 17 LVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQY-DFFPSATQTVYdnVKYIAFrdtygaadanyY 95
Cdd:cd03267 33 EVEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVaGLVPWKRRKKF--LRRIGV-----------V 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 96 YQQR----WNAHDQDETPDVREMLGeIKDEQLKN---ELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMD 168
Cdd:cd03267 100 FGQKtqlwWDLPVIDSFYLLAAIYD-LPPARFKKrldELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLD 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 169 NPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDK 219
Cdd:cd03267 179 EPTIGLDVVAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDK 229
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
262-465 |
8.88e-13 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 68.50 E-value: 8.88e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRYDD--RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadN----PQSyaCDISLFGRKRgTGE 335
Cdd:PRK13635 1 MKEEIIRVEHISFRYPDaaTYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLL---NglllPEA--GTITVGGMVL-SEE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 SIWEIKKHIGYVspemhrayLKNlPAIEIVASGLHDSI--GLYKRPQP-EQM------AVCEWWMDIFgiagLKDKPFlQ 406
Cdd:PRK13635 75 TVWDVRRQVGMV--------FQN-PDNQFVGATVQDDVafGLENIGVPrEEMvervdqALRQVGMEDF----LNREPH-R 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 407 LSSGE-QRLAlLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13635 141 LSGGQkQRVA-IAGVLALQPDIIILDEATSMLDPRGRREVLETVRQLKEQKGITVLSITH 199
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
272-481 |
9.22e-13 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 67.68 E-value: 9.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLvcadnpqsyacdisLFGRKRGT-GESIWEIKKHIGYVspe 350
Cdd:COG2401 36 VELRVVERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRL--------------LAGALKGTpVAGCVDVPDNQFGR--- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 mhraylkNLPAIEIVASglhdsiglyKRPQPEQMAVcewwmdiFGIAGLKD-----KPFLQLSSGEQRLALLARAFVKDP 425
Cdd:COG2401 99 -------EASLIDAIGR---------KGDFKDAVEL-------LNAVGLSDavlwlRRFKELSTGQKFRFRLALLLAERP 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLK 481
Cdd:COG2401 156 KLLVIDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIFV 211
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
268-437 |
9.83e-13 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 67.70 E-value: 9.83e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFG---RKRGT----GESI--- 337
Cdd:COG0410 5 EVENLHAGYGGIHVLHGVSLEVEEGEIVALLGRNGAGKTTLLK--------------AISGllpPRSGSirfdGEDItgl 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 --WEI-KKHIGYVsPEMHR--AYL---KNLpaieivasglhdSIGLYKRPQPEQM-AVCEWWMDIFgiaglkdkPFL--- 405
Cdd:COG0410 71 ppHRIaRLGIGYV-PEGRRifPSLtveENL------------LLGAYARRDRAEVrADLERVYELF--------PRLker 129
|
170 180 190
....*....|....*....|....*....|....*....
gi 2469828120 406 ------QLSSGEQR-LAlLARAFVKDPELLILDEPLHGL 437
Cdd:COG0410 130 rrqragTLSGGEQQmLA-IGRALMSRPKLLLLDEPSLGL 167
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
280-465 |
1.46e-12 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 67.11 E-value: 1.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 280 TILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGR--KRGTGESIWEIK-KHIGYV------SPE 350
Cdd:PRK10584 24 SILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGS-SGEVSLVGQplHQMDEEARAKLRaKHVGFVfqsfmlIPT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 MHRAYLKNLPAI---------EIVASGLHDSIGLYKRpqpeqmavcewwmdifgiagLKDKPfLQLSSGEQRLALLARAF 421
Cdd:PRK10584 103 LNALENVELPALlrgessrqsRNGAKALLEQLGLGKR--------------------LDHLP-AQLSGGEQQRVALARAF 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 422 VKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10584 162 NGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLILVTH 205
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
24-200 |
1.67e-12 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 67.08 E-value: 1.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD--------------------F-----FPSatQTVYDNV 78
Cdd:cd03219 19 VSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDgeditglppheiarlgigrtFqiprlFPE--LTVLENV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 79 KyIAFRdtygAADANYYYQQRWNAHDQDETPDVREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQLTKTL 158
Cdd:cd03219 97 M-VAAQ----ARTGSGLLLARARREEREARERAEELL-------------ERVGLADLADRPAGELSYGQQRRLEIARAL 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2469828120 159 LTAPRVLIMDNPFIGLDAPTRELLFSLLERLtKMSSVQIILV 200
Cdd:cd03219 159 ATDPKLLLLDEPAAGLNPEETEELAELIREL-RERGITVLLV 199
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
265-449 |
1.97e-12 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 66.80 E-value: 1.97e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC----ADNPQSY--ACDIS---LFGRKRgtge 335
Cdd:cd03218 2 RAENLSK---RYGKRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVglvkPDSGKILldGQDITklpMHKRAR---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 siweikKHIGYVSPEMhrAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:cd03218 75 ------LGIGYLPQEA--SIFRKLTVEENILAVLE----IRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRV 142
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI 449
Cdd:cd03218 143 EIARALATNPKFLLLDEPFAGVDPIAVQDIQKII 176
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
22-215 |
2.83e-12 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 66.20 E-value: 2.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD---------------------------FFPsatqTV 74
Cdd:COG1122 18 DDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDgkditkknlrelrrkvglvfqnpddqlFAP----TV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 75 YDNVkyiAFrdtygaADANYyyqqrwnAHDQDETPD-VREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQ 153
Cdd:COG1122 94 EEDV---AF------GPENL-------GLPREEIRErVEEAL-------------ELVGLEHLADRPPHELSGGQKQRVA 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 154 LTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKmSSVQIILVLSMLDDIPSFITHVI 215
Cdd:COG1122 145 IAGVLAMEPEVLVLDEPTAGLDPRGRRELLELLKRLNK-EGKTVIIVTHDLDLVAELADRVI 205
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
267-465 |
3.35e-12 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 66.14 E-value: 3.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTIlnELDWTVRRGEKWALSGENGAGKSTLLSLVCadnpqsyacdislfgrkrgtgesiweikkhiGY 346
Cdd:PRK10771 2 LKLTDITWLYHHLPM--RFDLTVERGERVAILGPSGAGKSTLLNLIA-------------------------------GF 48
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEMHRAYLK---------------------NL-PAIEI---VASGLHDSIGL--YKRPQPEQMAvcewwmDIFGIAGL 399
Cdd:PRK10771 49 LTPASGSLTLNgqdhtttppsrrpvsmlfqenNLfSHLTVaqnIGLGLNPGLKLnaAQREKLHAIA------RQMGIEDL 122
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 400 KDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10771 123 LARLPGQLSGGQRQRVALARCLVREQPILLLDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSH 188
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
267-469 |
3.49e-12 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 67.80 E-value: 3.49e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYacdislfGRKRGTGESIWEI---KKH 343
Cdd:PRK10851 3 IEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTS-------GHIRFHGTDVSRLharDRK 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSpeMHRAYLKNLPAIEIVASGLhdSIgLYKRPQPEQMAVCEWWM---DIFGIAGLKDKPFLQLSSGE-QRLALlAR 419
Cdd:PRK10851 76 VGFVF--QHYALFRHMTVFDNIAFGL--TV-LPRRERPNAAAIKAKVTqllEMVQLAHLADRYPAQLSGGQkQRVAL-AR 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 420 AFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:PRK10851 150 ALAVEPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEE 199
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
35-478 |
4.51e-12 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 68.12 E-value: 4.51e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 35 AIVGPNGGGKSLFVDTLTGKYPLREGTLQYD----FFPSATQ-------------------TVYDNVkYIA-FRDTYGAA 90
Cdd:COG1129 34 ALLGENGAGKSTLMKILSGVYQPDSGEILLDgepvRFRSPRDaqaagiaiihqelnlvpnlSVAENI-FLGrEPRRGGLI 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 91 DanyyyqqrWNAHDQDetpdVREMLGEIKdeqlknelfelFRIEPllDKKIILLSSGElRkfQLT---KTLLTAPRVLIM 167
Cdd:COG1129 113 D--------WRAMRRR----ARELLARLG-----------LDIDP--DTPVGDLSVAQ-Q--QLVeiaRALSRDARVLIL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 168 DNPFIGLDAPTRELLFSLLERLTKmSSVQIIlvlsmlddipsFITHvipvdKM-EVFpkvereAYLDA---FRD------ 237
Cdd:COG1129 165 DEPTASLTEREVERLFRIIRRLKA-QGVAII-----------YISH-----RLdEVF------EIADRvtvLRDgrlvgt 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 238 RDIA-VSFDELQKRII-----DLPYDGNNYDSDEVVKLNKVSirydDRTILNELDWTVRRGEKWALSGENGAGKSTLLSL 311
Cdd:COG1129 222 GPVAeLTEDELVRLMVgreleDLFPKRAAAPGEVVLEVEGLS----VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARA 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 312 VC-ADNPQSyaCDISLFGRKRGTGeSIWE-IKKHIGYVsPE--------MHRAYLKN--LPAIEIVASGlhdsiGLYKRP 379
Cdd:COG1129 298 LFgADPADS--GEIRLDGKPVRIR-SPRDaIRAGIAYV-PEdrkgeglvLDLSIRENitLASLDRLSRG-----GLLDRR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 380 qpEQMAVCEWWMDIFGI--AGLkDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkD 457
Cdd:COG1129 369 --RERALAEEYIKRLRIktPSP-EQPVGNLSGGNQQKVVLAKWLATDPKVLILDEPTRGIDVGAKAEIYRLIRELAAE-G 444
|
490 500
....*....|....*....|...
gi 2469828120 458 KTMIMVThyeSELPD--TITNRI 478
Cdd:COG1129 445 KAVIVIS---SELPEllGLSDRI 464
|
|
| LolD_lipo_ex |
TIGR02211 |
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ... |
280-465 |
5.66e-12 |
|
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 131266 [Multi-domain] Cd Length: 221 Bit Score: 65.07 E-value: 5.66e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 280 TILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGR---KRGTGESIWEIKKHIGYVSPEMHraY 355
Cdd:TIGR02211 19 RVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGGlDNPTS--GEVLFNGQslsKLSSNERAKLRNKKLGFIYQFHH--L 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 356 LKNLPAIEIVASGLhdSIGLYKRPQPEQMAvcewwMDIFGIAGLKD----KPFlQLSSGEQRLALLARAFVKDPELLILD 431
Cdd:TIGR02211 95 LPDFTALENVAMPL--LIGKKSVKEAKERA-----YEMLEKVGLEHrinhRPS-ELSGGERQRVAIARALVNQPSLVLAD 166
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 432 EPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:TIGR02211 167 EPTGNLDNNNAKIIFDLMLELNRELNTSFLVVTH 200
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
266-478 |
5.81e-12 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 65.30 E-value: 5.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDR----TILNELDWTVRRGEKWALSGENGAGKSTLLSLV-CADNPQSYAcdISLFGRKRGT--GESIW 338
Cdd:cd03258 1 MIELKNVSKVFGDTggkvTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCInGLERPTSGS--VLVDGTDLTLlsGKELR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVSpeMHRAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLAlL 417
Cdd:cd03258 79 KARRRIGMIF--QHFNLLSSRTVFENVALPLE----IAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQkQRVG-I 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHyESELPDTITNRI 478
Cdd:cd03258 152 ARALANNPKVLLCDEATSALDPETTQSILALLRDINRELGLTIVLITH-EMEVVKRICDRV 211
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
266-483 |
7.82e-12 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 66.51 E-value: 7.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLFGRKrgtgesiweikkhIG 345
Cdd:PRK09452 14 LVELRGISKSFDGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLI-AGFETPDSGRIMLDGQD-------------IT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPEmHR---------AYLKNLPAIEIVASGLHdsigLYKRPQPEqmaVCEWWMDIFGIAGLKD----KPfLQLSSGEQ 412
Cdd:PRK09452 80 HVPAE-NRhvntvfqsyALFPHMTVFENVAFGLR----MQKTPAAE---ITPRVMEALRMVQLEEfaqrKP-HQLSGGQQ 150
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 413 RLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE-LpdTITNRIFLKRN 483
Cdd:PRK09452 151 QRVAIARAVVNKPKVLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEaL--TMSDRIVVMRD 220
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
111-465 |
8.23e-12 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 67.50 E-value: 8.23e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 111 VREMLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLT 190
Cdd:COG1245 180 VRELLEKVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPSSYLDIYQRLNVARLIRELA 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 191 KMSSvQIILV---LSMLDDIPSFItHVI---P-----VDKmevfPKVEREA---YLDAF------RDRDIAVSFDELQKR 250
Cdd:COG1245 260 EEGK-YVLVVehdLAILDYLADYV-HILygePgvygvVSK----PKSVRVGinqYLDGYlpeenvRIRDEPIEFEVHAPR 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 251 IIDlpydgnnyDSDEVVKLNKVSIRYDDRTiLNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSyacdislfgr 329
Cdd:COG1245 334 REK--------EEETLVEYPDLTKSYGGFS-LEVEGGEIREGEVLGIVGPNGIGKTTFAKiLAGVLKPDE---------- 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 330 krgtGESIWEIKkhIGY----VSPEMH---RAYLKNlpaieIVASGLHDSIglykrpqpeqmavceWWMDI---FGIAGL 399
Cdd:COG1245 395 ----GEVDEDLK--ISYkpqyISPDYDgtvEEFLRS-----ANTDDFGSSY---------------YKTEIikpLGLEKL 448
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 400 KDKPFLQLSSGE-QRLAlLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1245 449 LDKNVKDLSGGElQRVA-IAACLSRDADLYLLDEPSAHLDVEQRLAVAKAIRRFAENRGKTAMVVDH 514
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
264-485 |
8.45e-12 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 65.52 E-value: 8.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYD---DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcaDNP-QSYACDISLFGRKRgTGESIWE 339
Cdd:PRK13650 2 SNIIEVKNLTFKYKedqEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLI--DGLlEAESGQIIIDGDLL-TEENVWD 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIGYVspemhrayLKNlPAIEIVASGLHDSI--GLYKR--PQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRL 414
Cdd:PRK13650 79 IRHKIGMV--------FQN-PDNQFVGATVEDDVafGLENKgiPHEEMKERVNEALELVGMQDFKEREPARLSGGQkQRV 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 415 ALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELpdTITNRIF-LKRNQV 485
Cdd:PRK13650 150 AI-AGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV--ALSDRVLvMKNGQV 218
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
263-479 |
8.72e-12 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 65.40 E-value: 8.72e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLlslvcadnpqsYACdisLFGRKRGTGESIWEIKK 342
Cdd:PRK11300 2 SQPLLSVSGLMMRFGGLLAVNNVNLEVREQEIVSLIGPNGAGKTTV-----------FNC---LTGFYKPTGGTILLRGQ 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HI-----------GYVSPEMHRAYLKNLPAIE--IVASGLHDSIGL---------YKRPQPEQMAVCEWWMDIFGIAGLK 400
Cdd:PRK11300 68 HIeglpghqiarmGVVRTFQHVRLFREMTVIEnlLVAQHQQLKTGLfsgllktpaFRRAESEALDRAATWLERVGLLEHA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 401 DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHyESELPDTITNRIF 479
Cdd:PRK11300 148 NRQAGNLAYGQQRRLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNEHNVTVLLIEH-DMKLVMGISDRIY 225
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
266-465 |
1.06e-11 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 64.63 E-value: 1.06e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadN----PQS---YACDISLFGRKRgtgeSIW 338
Cdd:COG1126 1 MIEIENLHKSFGDLEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCI---NlleePDSgtiTVDGEDLTDSKK----DIN 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYV------SPemhraylkNLPAIEIVASGLhdsIGLYKRPQPEQMAVCEWWMDIFGIAGLKDK-PFlQLSSGE 411
Cdd:COG1126 74 KLRRKVGMVfqqfnlFP--------HLTVLENVTLAP---IKVKKMSKAEAEERAMELLERVGLADKADAyPA-QLSGGQ 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 412 -QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:COG1126 142 qQRVAI-ARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDL-AKEGMTMVVVTH 194
|
|
| potA |
TIGR01187 |
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine ... |
297-483 |
1.12e-11 |
|
spermidine/putrescine ABC transporter ATP-binding subunit; This model describes spermidine/putrescine ABC transporter, ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. Polyamines like spermidine and putrescine play vital role in cell proliferation, differentiation, and ion homeostasis. The concentration of polyamines within the cell are regulated by biosynthesis, degradation and transport (uptake and efflux included). [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 162242 [Multi-domain] Cd Length: 325 Bit Score: 65.98 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 297 LSGENGAGKSTLLSLVCA-DNPQsyacdislFGRKRGTGESIWEIKKHIGYVSpEMHRAY--LKNLPAIEIVASGLHdsi 373
Cdd:TIGR01187 1 LLGPSGCGKTTLLRLLAGfEQPD--------SGSIMLDGEDVTNVPPHLRHIN-MVFQSYalFPHMTVEENVAFGLK--- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 374 gLYKRPQPEqmaVCEWWMDIFGIAGLKD----KPfLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI 449
Cdd:TIGR01187 69 -MRKVPRAE---IKPRVLEALRLVQLEEfadrKP-HQLSGGQQQRVALARALVFKPKILLLDEPLSALDKKLRDQMQLEL 143
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 450 EAFCKRKDKTMIMVTHYESElPDTITNRIFLKRN 483
Cdd:TIGR01187 144 KTIQEQLGITFVFVTHDQEE-AMTMSDRIAIMRK 176
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
34-452 |
1.49e-11 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 66.50 E-value: 1.49e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 34 IAIVGPNGGGKSLF------VDT-LTGKYPLREGT----LQYDFFPSATQTVYDNV-----KYIAFRDTYGAADANYyyq 97
Cdd:TIGR03719 34 IGVLGLNGAGKSTLlrimagVDKdFNGEARPQPGIkvgyLPQEPQLDPTKTVRENVeegvaEIKDALDRFNEISAKY--- 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 98 qrwnAHDQDETPDVREMLGEIKDEQLKNELFELFR-IE--------PLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMD 168
Cdd:TIGR03719 111 ----AEPDADFDKLAAEQAELQEIIDAADAWDLDSqLEiamdalrcPPWDADVTKLSGGERRRVALCRLLLSKPDMLLLD 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 169 NPFIGLDAPTrellFSLLERLTKMSSVQIILVLS---MLDDIPSFIthvIPVDKMEVFP--------------KVEREAY 231
Cdd:TIGR03719 187 EPTNHLDAES----VAWLERHLQEYPGTVVAVTHdryFLDNVAGWI---LELDRGRGIPwegnysswleqkqkRLEQEEK 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 232 LDAFRDRDIA---------------------VSFDEL-----QKRIIDL-------PYDGnnydsDEVVKLNKVSIRYDD 278
Cdd:TIGR03719 260 EESARQKTLKrelewvrqspkgrqakskarlARYEELlsqefQKRNETAeiyippgPRLG-----DKVIEAENLTKAFGD 334
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLfgrkrgtGESIweikkHIGYVSpEMHRAYLKN 358
Cdd:TIGR03719 335 KLLIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMI-TGQEQPDSGTIEI-------GETV-----KLAYVD-QSRDALDPN 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 LPAIEIVASGLhDSIGLYKRPQPEQmAVCEWwmdiFGIAGL-KDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGL 437
Cdd:TIGR03719 401 KTVWEEISGGL-DIIKLGKREIPSR-AYVGR----FNFKGSdQQKKVGQLSGGERNRVHLAKTLKSGGNVLLLDEPTNDL 474
|
490
....*....|....*
gi 2469828120 438 DTYNRRRVKKVIEAF 452
Cdd:TIGR03719 475 DVETLRALEEALLNF 489
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
277-438 |
1.51e-11 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 63.71 E-value: 1.51e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlVCADNPQSYACDISLFGRKRGTGESiweiKKHIGYVSpemHRAYL 356
Cdd:PRK13543 22 NEEPVFGPLDFHVDAGEALLVQGDNGAGKTTLLR-VLAGLLHVESGQIQIDGKTATRGDR----SRFMAYLG---HLPGL 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 357 K-NLPAIEivasGLHDSIGLYKRpQPEQMAVCEwwMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLH 435
Cdd:PRK13543 94 KaDLSTLE----NLHFLCGLHGR-RAKQMPGSA--LAIVGLAGYEDTLVRQLSAGQKKRLALARLWLSPAPLWLLDEPYA 166
|
...
gi 2469828120 436 GLD 438
Cdd:PRK13543 167 NLD 169
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
266-465 |
1.94e-11 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 63.74 E-value: 1.94e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSYACDISLFGRKRGTGESIWEIKKH 343
Cdd:PRK10908 1 MIRFEHVSKAYlGGRQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGiERPSAGKIWFSGHDITRLKNREVPFLRRQ 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSPEMH----RAYLKNLPAIEIVASGLHDSIglYKRPQPEqmavcewwMDIFGIAGlKDKPF-LQLSSGEQRLALLA 418
Cdd:PRK10908 81 IGMIFQDHHllmdRTVYDNVAIPLIIAGASGDDI--RRRVSAA--------LDKVGLLD-KAKNFpIQLSGGEQQRVGIA 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK10908 150 RAVVNKPAVLLADEPTGNLDDALSEGILRLFEEF-NRVGVTVLMATH 195
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
19-201 |
2.02e-11 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 62.45 E-value: 2.02e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIAFrdtygaadanyyyqq 98
Cdd:cd03214 13 TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKELARKIAY--------------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 99 rwnahdqdetpdVREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPT 178
Cdd:cd03214 78 ------------VPQAL-------------ELLGLAHLADRPFNELSGGERQRVLLARALAQEPPILLLDEPTSHLDIAH 132
|
170 180
....*....|....*....|...
gi 2469828120 179 RELLFSLLERLTKMSSVQIILVL 201
Cdd:cd03214 133 QIELLELLRRLARERGKTVVMVL 155
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
282-475 |
2.32e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 65.72 E-value: 2.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQ-SYACDISLFGRK------RGTGES-IWEIKKHIGYVsPEMHR 353
Cdd:PRK13549 21 LDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYPHgTYEGEIIFEGEElqasniRDTERAgIAIIHQELALV-KELSV 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 354 A---YLKNlpaiEIVASGLHDSIGLYKRpqpeqmavCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLIL 430
Cdd:PRK13549 100 LeniFLGN----EITPGGIMDYDAMYLR--------AQKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLIL 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 431 DEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESE---LPDTIT 475
Cdd:PRK13549 168 DEPTASLTESETAVLLDIIRDL-KAHGIACIYISHKLNEvkaISDTIC 214
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
278-473 |
2.37e-11 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 62.97 E-value: 2.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 278 DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPqsyacdiSLFGRKRGTGESIwEIKKHIG---YVSpemHRA 354
Cdd:PRK13539 14 GRVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLP-------PAAGTIKLDGGDI-DDPDVAEachYLG---HRN 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 355 YLK-NLPAIEIVA----------SGLHDSIglykrpqpeqmavcewwmDIFGIAGLKDKPFLQLSSGEQRLALLARAFVK 423
Cdd:PRK13539 83 AMKpALTVAENLEfwaaflggeeLDIAAAL------------------EAVGLAPLAHLPFGYLSAGQKRRVALARLLVS 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTHYESELPDT 473
Cdd:PRK13539 145 NRPIWILDEPTAALDAAAVALFAELIRAHLAQ-GGIVIAATHIPLGLPGA 193
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
228-469 |
2.68e-11 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 66.58 E-value: 2.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 228 REAYLDafRDRDIAvsfdELQKRIIDlpyDGNNYDsdeVVKLNKVSIRYDDRT--ILNELDWTVRRGEKWALSGENGAGK 305
Cdd:TIGR01257 1911 KEPIFD--EDDDVA----EERQRIIS---GGNKTD---ILRLNELTKVYSGTSspAVDRLCVGVRPGECFGLLGVNGAGK 1978
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 306 STLLSLVCADNPQSyACDISLFGRKRGTgeSIWEIKKHIGYVsPEmhraylknLPAIEIVASGlHDSIGLYKR----PQP 381
Cdd:TIGR01257 1979 TTTFKMLTGDTTVT-SGDATVAGKSILT--NISDVHQNMGYC-PQ--------FDAIDDLLTG-REHLYLYARlrgvPAE 2045
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 382 EQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMI 461
Cdd:TIGR01257 2046 EIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARRMLWNTIVSII-REGRAVV 2124
|
....*...
gi 2469828120 462 MVTHYESE 469
Cdd:TIGR01257 2125 LTSHSMEE 2132
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
144-454 |
3.00e-11 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 65.50 E-value: 3.00e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 144 LSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMssvqiiLVLSMLddipsFITHVIPVDK---- 219
Cdd:PRK15134 157 LSGGERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQE------LNMGLL-----FITHNLSIVRklad 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 220 ----MEVFPKVEREAyldafRDRDIAVSFDELQKRIIDLPYDGN----NYDSDEVVKLNKVSIRY-----------DDRT 280
Cdd:PRK15134 226 rvavMQNGRCVEQNR-----AATLFSAPTHPYTQKLLNSEPSGDpvplPEPASPLLDVEQLQVAFpirkgilkrtvDHNV 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 281 ILNELDWTVRRGEKWALSGENGAGKST----LLSLVCA-------DNPqsyacdISLFGRKRgtgesIWEIKKHIGYVSP 349
Cdd:PRK15134 301 VVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLINSqgeiwfdGQP------LHNLNRRQ-----LLPVRHRIQVVFQ 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EMHRAYLKNLPAIEIVASGL---HDSIGLYKRPQPEQMAVCEWWMDifgiAGLKDKPFLQLSSGE-QRLALlARAFVKDP 425
Cdd:PRK15134 370 DPNSSLNPRLNVLQIIEEGLrvhQPTLSAAQREQQVIAVMEEVGLD----PETRHRYPAEFSGGQrQRIAI-ARALILKP 444
|
330 340
....*....|....*....|....*....
gi 2469828120 426 ELLILDEPLHGLDtynrRRVKKVIEAFCK 454
Cdd:PRK15134 445 SLIILDEPTSSLD----KTVQAQILALLK 469
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
268-465 |
3.18e-11 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 63.32 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIryDDRtiLNELDWTVRRGEKWALSGENGAGKSTLLSlvCADNPQSYACDISLFGRKrgtgesiweikkhIGYV 347
Cdd:COG4138 2 QLNDVAV--AGR--LGPISAQVNAGELIHLIGPNGAGKSTLLA--RMAGLLPGQGEILLNGRP-------------LSDW 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SPE---MHRAYL----KNLPAIeivasGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDK---PFLQLSSGE-QRLaL 416
Cdd:COG4138 63 SAAelaRHRAYLsqqqSPPFAM-----PVFQYLALHQPAGASSEAVEQLLAQLAEALGLEDKlsrPLTQLSGGEwQRV-R 136
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 417 LARAFVK-----DPE--LLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMIMVTH 465
Cdd:COG4138 137 LAAVLLQvwptiNPEgqLLLLDEPMNSLDVAQQAALDRLLRELC-QQGITVVMSSH 191
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
269-465 |
3.56e-11 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 63.57 E-value: 3.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRK-RGTGesiweikKHIGYV 347
Cdd:PRK11248 4 ISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQ-HGSITLDGKPvEGPG-------AERGVV 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SpeMHRAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPEL 427
Cdd:PRK11248 76 F--QNEGLLPWRNVQDNVAFGLQ----LAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQL 149
|
170 180 190
....*....|....*....|....*....|....*...
gi 2469828120 428 LILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK11248 150 LLLDEPFGALDAFTREQMQTLLLKLWQETGKQVLLITH 187
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
199-465 |
3.86e-11 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 65.37 E-value: 3.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 199 LVLSMLDDIPSFITHVI---PvdKMEVFPKVEREAYldAFRDRDIAVSFDELQKRiidlpydgnnydsdevVKLNKVSIR 275
Cdd:PRK13657 284 LLIGRLDQVVAFINQVFmaaP--KLEEFFEVEDAVP--DVRDPPGAIDLGRVKGA----------------VEFDDVSFS 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 276 YDD-RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyacdislfGRKRGTGESIWEI-----KKHIGYVS 348
Cdd:PRK13657 344 YDNsRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLINLLQrVFDPQS--------GRILIDGTDIRTVtraslRRNIAVVF 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 349 PE---MHRAYLKNL-------------PAIEIVASglHDSIglYKRPQPEQMAVCEwwmdifgiAGLkdkpflQLSSGE- 411
Cdd:PRK13657 416 QDaglFNRSIEDNIrvgrpdatdeemrAAAERAQA--HDFI--ERKPDGYDTVVGE--------RGR------QLSGGEr 477
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 412 QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEafCKRKDKTMIMVTH 465
Cdd:PRK13657 478 QRLAI-ARALLKDPPILILDEATSALDVETEAKVKAALD--ELMKGRTTFIIAH 528
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
266-437 |
3.87e-11 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 62.97 E-value: 3.87e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADnPQSYACDIsLFGRKRGTGESIWEIKKHIG 345
Cdd:PRK11614 5 MLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGD-PRATSGRI-VFDGKDITDWQTAKIMREAV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPEMHRAYLKnLPAIEIVASGlhdsiGLYKRPQPEQMAVcEWWMDIFgiaglkdkPFLQ---------LSSGEQRLAL 416
Cdd:PRK11614 83 AIVPEGRRVFSR-MTVEENLAMG-----GFFAERDQFQERI-KWVYELF--------PRLHerriqragtMSGGEQQMLA 147
|
170 180
....*....|....*....|.
gi 2469828120 417 LARAFVKDPELLILDEPLHGL 437
Cdd:PRK11614 148 IGRALMSQPRLLLLDEPSLGL 168
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
275-465 |
5.97e-11 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 62.41 E-value: 5.97e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyacdislfGRkrgtgesiweIKKHiGYVSPemhr 353
Cdd:COG1134 35 RREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAgILEPTS--------GR----------VEVN-GRVSA---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 354 ayLknlpaIEiVASGLHDSI-------------GLYKRPQPEQMAvcewwmDIFGIAGLK---DKPFLQLSSGEQ-RLAl 416
Cdd:COG1134 92 --L-----LE-LGAGFHPELtgreniylngrllGLSRKEIDEKFD------EIVEFAELGdfiDQPVKTYSSGMRaRLA- 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 417 LARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:COG1134 157 FAVATAVDPDILLVDEVLAVGDAAFQKKCLARIREL-RESGRTVIFVSH 204
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
266-465 |
6.65e-11 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 62.72 E-value: 6.65e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL----SLVCADnpQSYACDISLFGRK-RGTGESIWEI 340
Cdd:PRK09984 4 IIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLrhlsGLITGD--KSAGSHIELLGRTvQREGRLARDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KK---HIGYVSPEMHraYLKNLPAIEIVASGLHDSIGLYK------RPQPEQMAVCEwwMDIFGIAGLKDKPFLQLSSGE 411
Cdd:PRK09984 82 RKsraNTGYIFQQFN--LVNRLSVLENVLIGALGSTPFWRtcfswfTREQKQRALQA--LTRVGMVHFAHQRVSTLSGGQ 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 412 QRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK09984 158 QQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLH 211
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
279-478 |
9.74e-11 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 64.65 E-value: 9.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYACdISLFGRKRGTgeSIWEIKKHIGyVSPEmHRAYLKN 358
Cdd:TIGR01257 943 RPAVDRLNITFYENQITAFLGHNGAGKTTTLSILTGLLPPTSGT-VLVGGKDIET--NLDAVRQSLG-MCPQ-HNILFHH 1017
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 LpaieIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLD 438
Cdd:TIGR01257 1018 L----TVAEHILFYAQLKGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVD 1093
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 439 TYNRRRVKKVIEAFckRKDKTMIMVTHYESElPDTITNRI 478
Cdd:TIGR01257 1094 PYSRRSIWDLLLKY--RSGRTIIMSTHHMDE-ADLLGDRI 1130
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
267-465 |
1.04e-10 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 61.47 E-value: 1.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYD-DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRKrGTGESIWEIKKHI 344
Cdd:cd03254 3 IEFENVNFSYDeKKPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRfYDPQK--GQILIDGID-IRDISRKSLRSMI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMHraylknlpaieIVASGLHDSIgLYKRPQPEQmavcEWWMDIFGIAGLKDkpFLQ----------------LS 408
Cdd:cd03254 80 GVVLQDTF-----------LFSGTIMENI-RLGRPNATD----EEVIEAAKEAGAHD--FIMklpngydtvlgenggnLS 141
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 409 SGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:cd03254 142 QGERQLLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKL--MKGRTSIIIAH 196
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
276-450 |
1.09e-10 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 61.83 E-value: 1.09e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 276 YDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAC------DISLF---GRKRgtgesiweikKHIGY 346
Cdd:PRK10895 13 YKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNiiiddeDISLLplhARAR----------RGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEMhrAYLKNLPAIEIVASGLHDSIGLYKRPQPEQmavCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPE 426
Cdd:PRK10895 83 LPQEA--SIFRRLSVYDNLMAVLQIRDDLSAEQREDR---ANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPK 157
|
170 180
....*....|....*....|....
gi 2469828120 427 LLILDEPLHGLDTYNRRRVKKVIE 450
Cdd:PRK10895 158 FILLDEPFAGVDPISVIDIKRIIE 181
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
265-478 |
1.56e-10 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 62.55 E-value: 1.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcADNPQSYACDISLFGRkrgtgesiwEIKKHI 344
Cdd:PRK11607 21 EIRNLTK---SFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRML-AGFEQPTAGQIMLDGV---------DLSHVP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSP--EMHRAY--LKNLPAIEIVASGLHDSiglyKRPQPEQMAVCEWWMDIFGIAGL-KDKPFlQLSSGE-QRLALlA 418
Cdd:PRK11607 88 PYQRPinMMFQSYalFPHMTVEQNIAFGLKQD----KLPKAEIASRVNEMLGLVHMQEFaKRKPH-QLSGGQrQRVAL-A 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESElPDTITNRI 478
Cdd:PRK11607 162 RSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEE-AMTMAGRI 220
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
263-465 |
1.56e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 61.60 E-value: 1.56e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlVCADNPQSYACDISLFGRKRGTGESIWEI-- 340
Cdd:PRK14246 7 AEDVFNISRLYLYINDKAILKDITIKIPNNSIFGIMGPSGSGKSTLLK-VLNRLIEIYDSKIKVDGKVLYFGKDIFQIda 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 ---KKHIGYV----SPEMHRAYLKNLpAIEIVASGLHDSIGLyKRPQPEQMAVCEWWMDIFGIAglkDKPFLQLSSGEQR 413
Cdd:PRK14246 86 iklRKEVGMVfqqpNPFPHLSIYDNI-AYPLKSHGIKEKREI-KKIVEECLRKVGLWKEVYDRL---NSPASQLSGGQQQ 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 414 LALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:PRK14246 161 RLTIARALALKPKVLLMDEPTSMIDIVNSQAIEKLITEL--KNEIAIVIVSH 210
|
|
| SufC |
COG0396 |
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ... |
272-467 |
1.65e-10 |
|
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440165 [Multi-domain] Cd Length: 245 Bit Score: 61.24 E-value: 1.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIryDDRTILNELDWTVRRGEKWALSGENGAGKSTLlSLVCADNPqSY---ACDISLfgrkrgTGESI--WEI----KK 342
Cdd:COG0396 8 VSV--EGKEILKGVNLTIKPGEVHAIMGPNGSGKSTL-AKVLMGHP-KYevtSGSILL------DGEDIleLSPderaRA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYV--SPemhraylknlpaIEI----VASGLHDSIGlyKRPQPEQMA------VCEWwMDIFGIaglkDKPFLQ---- 406
Cdd:COG0396 78 GIFLAfqYP------------VEIpgvsVSNFLRTALN--ARRGEELSAreflklLKEK-MKELGL----DEDFLDryvn 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 407 --LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYE 467
Cdd:COG0396 139 egFSGGEKKRNEILQMLLLEPKLAILDETDSGLDIDALRIVAEGVNKL-RSPDRGILIITHYQ 200
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
282-466 |
1.70e-10 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 62.03 E-value: 1.70e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSL-------------VCADNPQ----SYACDISL-FGRKrgtGESIW----- 338
Cdd:COG4586 38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMltgilvptsgevrVLGYVPFkrrkEFARRIGVvFGQR---SQLWWdlpai 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 ---EIKKHIGYVSPEmhrAYLKNLpaieivasglhdsiglykrpqpEQMAvcewwmDIFGIAGLKDKPFLQLSSGEQRLA 415
Cdd:COG4586 115 dsfRLLKAIYRIPDA---EYKKRL----------------------DELV------ELLDLGELLDTPVRQLSLGQRMRC 163
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHY 466
Cdd:COG4586 164 ELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHD 214
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
271-474 |
2.05e-10 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 61.20 E-value: 2.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 271 KVSIryDDRTILNELDWTVRRGEKWALSGENGAGKSTLlSLVCADNPqSYACdisLFGRKRGTGESIWEIkkhigyvSPE 350
Cdd:CHL00131 14 HASV--NENEILKGLNLSINKGEIHAIMGPNGSGKSTL-SKVIAGHP-AYKI---LEGDILFKGESILDL-------EPE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 MhRAYLKNLPA----IEIVASGLHDSIGL--------YKRPQPEQMAVCEWWMDIFGIAGLkDKPFLQ------LSSGEQ 412
Cdd:CHL00131 80 E-RAHLGIFLAfqypIEIPGVSNADFLRLaynskrkfQGLPELDPLEFLEIINEKLKLVGM-DPSFLSrnvnegFSGGEK 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 413 R------LALLarafvkDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESEL----PDTI 474
Cdd:CHL00131 158 KrneilqMALL------DSELAILDETDSGLDIDALKIIAEGINKL-MTSENSIILITHYQRLLdyikPDYV 222
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
264-465 |
2.30e-10 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 61.29 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYDDRT-ILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADN-PQSYAcdISLFGRKRgTGESIWEIK 341
Cdd:PRK13647 2 DNIIEVEDLHFRYKDGTkALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYlPQRGR--VKVMGREV-NAENEKWVR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVSPEmhraylknlPAIEIVASGLHDSIGLYKR----PQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALL 417
Cdd:PRK13647 79 SKVGLVFQD---------PDDQVFSSTVWDDVAFGPVnmglDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAI 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK13647 150 AGVLAMDPDVIVLDEPMAYLDPRGQETLMEILDRL-HNQGKTVIVATH 196
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
24-215 |
2.44e-10 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 59.99 E-value: 2.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAtqtvydnvkyIAFRDTYGaadanYYYQQRwnAH 103
Cdd:cd03269 19 ISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLD----------IAARNRIG-----YLPEER--GL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 104 DQDETpdVREML-------GEIKDEQLKN--ELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGL 174
Cdd:cd03269 82 YPKMK--VIDQLvylaqlkGLKKEEARRRidEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPELLILDEPFSGL 159
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2469828120 175 DAPTRELLFSLLERLtKMSSVQIILVLSMLDDIPSFITHVI 215
Cdd:cd03269 160 DPVNVELLKDVIREL-ARAGKTVILSTHQMELVEELCDRVL 199
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
267-465 |
2.48e-10 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 62.92 E-value: 2.48e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYD-DRTILNELDWTVRRGEKWALSGENGAGKSTLLSL-----------VCADN------------------ 316
Cdd:COG5265 358 VRFENVSFGYDpERPILKGVSFEVPAGKTVAIVGPSGAGKSTLARLlfrfydvtsgrILIDGqdirdvtqaslraaigiv 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 317 PQsyacDISLFgrkrgtGESIWEikkHIGYVSPEMHRAylknlpaiEIV----ASGLHDSI-GLykrPQPEQMAVCEwwm 391
Cdd:COG5265 438 PQ----DTVLF------NDTIAY---NIAYGRPDASEE--------EVEaaarAAQIHDFIeSL---PDGYDTRVGE--- 490
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 392 difgiAGLKdkpflqLSSGE-QRLAlLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:COG5265 491 -----RGLK------LSGGEkQRVA-IARTLLKNPPILIFDEATSALDSRTERAIQAALREV--ARGRTTLVIAH 551
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
267-465 |
2.81e-10 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 62.38 E-value: 2.81e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTI-LNELDWTVRRGEKWALSGENGAGKSTLLSL--------------------------------VC 313
Cdd:TIGR02868 335 LELRDLSAGYPGAPPvLDGVSLDLPPGERVAILGPSGSGKSTLLATlaglldplqgevtldgvpvssldqdevrrrvsVC 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 314 ADNPQSYACDIS---LFGRKRGTGESIWEikkhigyvspemhraylknlpAIEIVasGLHDSIglykRPQPEQMavcEWW 390
Cdd:TIGR02868 415 AQDAHLFDTTVRenlRLARPDATDEELWA---------------------ALERV--GLADWL----RALPDGL---DTV 464
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 391 MDIFGIAglkdkpflqLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkdKTMIMVTH 465
Cdd:TIGR02868 465 LGEGGAR---------LSGGErQRLAL-ARALLADAPILLLDEPTEHLDAETADELLEDLLAALSG--RTVVLITH 528
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
266-475 |
3.44e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 62.15 E-value: 3.44e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQ-SYACDIsLFGRKRGTGESIWEI-KKH 343
Cdd:TIGR02633 1 LLEMKGIVKTFGGVKALDGIDLEVRPGECVGLCGENGAGKSTLMKILSGVYPHgTWDGEI-YWSGSPLKASNIRDTeRAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSPEMhrAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKD-KPFLQLSSGEQRLALLARAFV 422
Cdd:TIGR02633 80 IVIIHQEL--TLVPELSVAENIFLGNEITLPGGRMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGGGQQQLVEIAKALN 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELP---DTIT 475
Cdd:TIGR02633 158 KQARLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKavcDTIC 212
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
265-438 |
3.55e-10 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 60.04 E-value: 3.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKST----LLSLVCADNPQsyacdISLFGRkrgtgesiwEI 340
Cdd:COG1137 5 EAENLVK---SYGKRTVVKDVSLEVNQGEIVGLLGPNGAGKTTtfymIVGLVKPDSGR-----IFLDGE---------DI 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHigyvsPeMH-RA-----YL-------------KNLPAI-EIVasglhdsiglyKRPQPEQMAVCEWWMDIFGIAGLK 400
Cdd:COG1137 68 THL-----P-MHkRArlgigYLpqeasifrkltveDNILAVlELR-----------KLSKKEREERLEELLEEFGITHLR 130
|
170 180 190
....*....|....*....|....*....|....*...
gi 2469828120 401 DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLD 438
Cdd:COG1137 131 KSKAYSLSGGERRRVEIARALATNPKFILLDEPFAGVD 168
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
266-472 |
3.99e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 60.90 E-value: 3.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRT-----ILNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADNPQSYACDISLFGRKRGtgES 336
Cdd:PRK13643 1 MIKFEKVNYTYQPNSpfasrALFDIDLEVKKGSYTALIGHTGSGKSTLLQhlngLLQPTEGKVTVGDIVVSSTSKQ--KE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 337 IWEIKKHIGYVSpEMHRAYLKNLPAIEIVASGLHDsIGLYKRpQPEQMAVCEWWMDIFGIAGLKDKPFlQLSSGEQRLAL 416
Cdd:PRK13643 79 IKPVRKKVGVVF-QFPESQLFEETVLKDVAFGPQN-FGIPKE-KAEKIAAEKLEMVGLADEFWEKSPF-ELSGGQMRRVA 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 417 LARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESELPD 472
Cdd:PRK13643 155 IAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESI-HQSGQTVVLVTHLMDDVAD 209
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
282-465 |
4.36e-10 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 60.35 E-value: 4.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSL-----------VCADNPqsyacDISLFGRKRgtgesIWEIKKH-IGYVSp 349
Cdd:cd03294 40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCinrlieptsgkVLIDGQ-----DIAAMSRKE-----LRELRRKkISMVF- 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 eMHRAYLKNLPAIEIVASGLHdsigLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPELLI 429
Cdd:cd03294 109 -QSFALLPHRTVLENVAFGLE----VQGVPRAEREERAAEALELVGLEGWEHKYPDELSGGMQQRVGLARALAVDPDILL 183
|
170 180 190
....*....|....*....|....*....|....*.
gi 2469828120 430 LDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03294 184 MDEAFSALDPLIRREMQDELLRLQAELQKTIVFITH 219
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
24-218 |
4.94e-10 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 59.41 E-value: 4.94e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQ-----------------TVYDNVkyiafrdT 86
Cdd:cd03293 23 ISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTGPgpdrgyvfqqdallpwlTVLDNV-------A 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 87 YGAadanyyyqqrwnahdqdetpdvrEMLGEIKDEQLK--NELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRV 164
Cdd:cd03293 96 LGL-----------------------ELQGVPKAEAREraEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 165 LIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV-------LSMLDDI------PSFITHVIPVD 218
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVthdideaVFLADRVvvlsarPGRIVAEVEVD 219
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
266-485 |
5.14e-10 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 62.05 E-value: 5.14e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRY---DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcadnpqsyacdISLFGRKRGT----GESIW 338
Cdd:TIGR00958 478 LIEFQDVSFSYpnrPDVPVLKGLTFTLHPGEVVALVGPSGSGKSTVAALL-----------QNLYQPTGGQvlldGVPLV 546
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 E-----IKKHIGYVSPE---MHR------AY-LKNLPAIEI----VASGLHDSIGlyKRPQpeqmavcewwmdifGIAGL 399
Cdd:TIGR00958 547 QydhhyLHRQVALVGQEpvlFSGsvreniAYgLTDTPDEEImaaaKAANAHDFIM--EFPN--------------GYDTE 610
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 400 KDKPFLQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTynrrRVKKVIEAFCKRKDKTMIMVTHYESelpdTITNR- 477
Cdd:TIGR00958 611 VGEKGSQLSGGQkQRIAI-ARALVRKPRVLILDEATSALDA----ECEQLLQESRSRASRTVLLIAHRLS----TVERAd 681
|
250
....*....|
gi 2469828120 478 --IFLKRNQV 485
Cdd:TIGR00958 682 qiLVLKKGSV 691
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
281-465 |
5.66e-10 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 59.44 E-value: 5.66e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 281 ILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRKRGTGESI--WEIKKH-IGYVSPEMHraYL 356
Cdd:PRK11629 24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGlDTPTS--GDVIFNGQPMSKLSSAakAELRNQkLGFIYQFHH--LL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 357 KNLPAIEIVASGLhdSIGLYKRPQPEQMAvcewwMDIFGIAGLKDKPF---LQLSSGE-QRLALlARAFVKDPELLILDE 432
Cdd:PRK11629 100 PDFTALENVAMPL--LIGKKKPAEINSRA-----LEMLAAVGLEHRANhrpSELSGGErQRVAI-ARALVNNPRLVLADE 171
|
170 180 190
....*....|....*....|....*....|...
gi 2469828120 433 PLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK11629 172 PTGNLDARNADSIFQLLGELNRLQGTAFLVVTH 204
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
267-465 |
6.89e-10 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 59.42 E-value: 6.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLV----CADNPQsyacdISLFGRKRGTGESIWeI 340
Cdd:cd03252 1 ITFEHVRFRYkpDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIqrfyVPENGR-----VLVDGHDLALADPAW-L 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHIGYVSPE---MHRAYLKNL----PA-----IEIVAS--GLHDSIglykrpqpeqMAVCEWWMDIFGIAGLKdkpflq 406
Cdd:cd03252 75 RRQVGVVLQEnvlFNRSIRDNIaladPGmsmerVIEAAKlaGAHDFI----------SELPEGYDTIVGEQGAG------ 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 407 LSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkrKDKTMIMVTH 465
Cdd:cd03252 139 LSGGQrQRIAI-ARALIHNPRILIFDEATSALDYESEHAIMRNMHDIC--AGRTVIIIAH 195
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
272-465 |
7.12e-10 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 59.72 E-value: 7.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQ----SYACDISLFGRKRGTGESIWEIKKHIGYV 347
Cdd:PRK14271 27 LTLGFAGKTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKvsgyRYSGDVLLGGRSIFNYRDVLEFRRRVGML 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 speMHRAYLKNLPAIEIVASGL--HDSIglykrPQPEQMAVCEWWMDIFGIAG-----LKDKPFlQLSSGEQRLALLARA 420
Cdd:PRK14271 107 ---FQRPNPFPMSIMDNVLAGVraHKLV-----PRKEFRGVAQARLTEVGLWDavkdrLSDSPF-RLSGGQQQLLCLART 177
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkdKTMIMVTH 465
Cdd:PRK14271 178 LAVNPEVLLLDEPTSALDPTTTEKIEEFIRSLADR--LTVIIVTH 220
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
263-469 |
9.61e-10 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 59.33 E-value: 9.61e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDD------RTILNELDWTVRRGEKWALSGENGAGKSTLL----SLVCADNPQSYACDISlfgrkRG 332
Cdd:PRK13633 1 MNEMIKCKNVSYKYESneesteKLALDDVNLEVKKGEFLVILGRNGSGKSTIAkhmnALLIPSEGKVYVDGLD-----TS 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 333 TGESIWEIKKHIGYVspemhrayLKNlPAIEIVASGLHDSIGLykrpQPEQMAV--------CEWWMDIFGIAGLKDKPF 404
Cdd:PRK13633 76 DEENLWDIRNKAGMV--------FQN-PDNQIVATIVEEDVAF----GPENLGIppeeirerVDESLKKVGMYEYRRHAP 142
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 405 LQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:PRK13633 143 HLLSGGQkQRVAI-AGILAMRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEE 207
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
119-236 |
1.02e-09 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 59.89 E-value: 1.02e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 119 KDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAP-TRELLfSLLERLTKMSSVQI 197
Cdd:PRK11144 104 SMVAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPrKRELL-PYLERLAREINIPI 182
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2469828120 198 ILVLSMLDDIPSFITHVIPVD--KMEVFPKVEREAYLDAFR 236
Cdd:PRK11144 183 LYVSHSLDEILRLADRVVVLEqgKVKAFGPLEEVWASSAMR 223
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
263-465 |
1.06e-09 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 59.13 E-value: 1.06e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFGRKR-GTGEsiwei 340
Cdd:PRK15056 3 QQAGIVVNDVTVTWrNGHTALRDASFTVPGGSIAALVGVNGSGKSTLFK--------------ALMGFVRlASGK----- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 kkhIGYVSPEMHRAYLKNLPAI----------------EIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPF 404
Cdd:PRK15056 64 ---ISILGQPTRQALQKNLVAYvpqseevdwsfpvlveDVVMMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQI 140
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 405 LQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK15056 141 GELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARIISLLREL-RDEGKTMLVSTH 200
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
263-465 |
1.38e-09 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 58.63 E-value: 1.38e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLV--CAD-NPQsyacdISLFGRKRGTGESIW- 338
Cdd:PRK14239 2 TEPILQVSDLSVYYNKKKALNSVSLDFYPNEITALIGPSGSGKSTLLRSInrMNDlNPE-----VTITGSIVYNGHNIYs 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 ------EIKKHIGYVspemhraylknlpaieivasglhdsiglYKRPQPEQMAVCEwwMDIFG--IAGLKDKPFLQ---- 406
Cdd:PRK14239 77 prtdtvDLRKEIGMV----------------------------FQQPNPFPMSIYE--NVVYGlrLKGIKDKQVLDeave 126
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 407 ----------------------LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVT 464
Cdd:PRK14239 127 kslkgasiwdevkdrlhdsalgLSGGQQQRVCIARVLATSPKIILLDEPTSALDPISAGKIEETLLGL--KDDYTMLLVT 204
|
.
gi 2469828120 465 H 465
Cdd:PRK14239 205 R 205
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
24-200 |
1.46e-09 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 58.51 E-value: 1.46e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD--------------------F-----FPSatQTVYDNV 78
Cdd:COG0411 23 VSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDgrditglpphriarlgiartFqnprlFPE--LTVLENV 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 79 KyIA--FRDTYGAADAnyyyQQRWNAHDQDEtpdvREMLGEIkDEQLknelfELFRIEPLLDKKIILLSSGELRKFQLTK 156
Cdd:COG0411 101 L-VAahARLGRGLLAA----LLRLPRARREE----REARERA-EELL-----ERVGLADRADEPAGNLSYGQQRRLEIAR 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 157 TLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV 200
Cdd:COG0411 166 ALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLI 209
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
264-482 |
1.53e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 58.95 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 264 DEVVKLNKVSIRYDDRTILNELD---WTVRRGEKWALSGENGAGKSTLLSLVcaDNPQSYACDISLFGRKRGTGESIWEI 340
Cdd:PRK13642 2 NKILEVENLVFKYEKESDVNQLNgvsFSITKGEWVSIIGQNGSGKSTTARLI--DGLFEEFEGKVKIDGELLTAENVWNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKHIGYVspemhrayLKNlPAIEIVASGLHDSIGLYKR----PQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRLAL 416
Cdd:PRK13642 80 RRKIGMV--------FQN-PDNQFVGATVEDDVAFGMEnqgiPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVA 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 417 LARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDtiTNRIFLKR 482
Cdd:PRK13642 151 VAGIIALRPEIIILDESTSMLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS--SDRILVMK 214
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
279-465 |
1.69e-09 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 57.18 E-value: 1.69e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSYACDISLFGRKRgtgeSIWEIKKHIGYVSPEMHraylk 357
Cdd:cd03213 22 KQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNaLAGRRTGLGVSGEVLINGRPL----DKRSFRKIIGYVPQDDI----- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 358 nlpaieivasgLHdsiglykrpqpEQMAVCEWWMdiFgIAGLKdkpflQLSSGEQRLALLARAFVKDPELLILDEPLHGL 437
Cdd:cd03213 93 -----------LH-----------PTLTVRETLM--F-AAKLR-----GLSGGERKRVSIALELVSNPSLLFLDEPTSGL 142
|
170 180
....*....|....*....|....*...
gi 2469828120 438 DTYNRRRVKKVIEAFCKRkDKTMIMVTH 465
Cdd:cd03213 143 DSSSALQVMSLLRRLADT-GRTIICSIH 169
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
265-470 |
2.31e-09 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 57.27 E-value: 2.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNkvsIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGRKRGTGESIWEikKH 343
Cdd:PRK13540 3 DVIELD---FDYHDQPLLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGlLNPEK--GEILFERQSIKKDLCTYQ--KQ 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYVSpemHRAYLK-NLPAIEIVASGLHDSIGlykrpqpeQMAVCEwWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:PRK13540 76 LCFVG---HRSGINpYLTLRENCLYDIHFSPG--------AVGITE-LCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWM 143
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESEL 470
Cdd:PRK13540 144 SKAKLWLLDEPLVALDELSLLTIITKIQEH-RAKGGAVLLTSHQDLPL 190
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
15-191 |
3.31e-09 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 56.90 E-value: 3.31e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 15 NPLVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGK---YPLREGTLQYDFFPSATQTVYDNVKYI----AFRDTY 87
Cdd:cd03234 17 NKYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRvegGGTTSGQILFNGQPRKPDQFQKCVAYVrqddILLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 88 GAADANYYYQ----QRWNAHDQDETPDVREMLGEIKDEQLKNELFELfrieplldkkiilLSSGELRKFQLTKTLLTAPR 163
Cdd:cd03234 97 TVRETLTYTAilrlPRKSSDAIRKKRVEDVLLRDLALTRIGGNLVKG-------------ISGGERRRVSIAVQLLWDPK 163
|
170 180
....*....|....*....|....*...
gi 2469828120 164 VLIMDNPFIGLDAPTRELLFSLLERLTK 191
Cdd:cd03234 164 VLILDEPTSGLDSFTALNLVSTLSQLAR 191
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
18-450 |
4.28e-09 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 58.52 E-value: 4.28e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 18 VRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD-------------------------FFPSatQ 72
Cdd:PRK15439 24 VEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGgnpcarltpakahqlgiylvpqeplLFPN--L 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 73 TVYDNvkyIAFRDTYGAADANYYYQ--QRWNAHdqdETPDVREMLGEIKDEQLknelFELFRieplldkkiillssGELR 150
Cdd:PRK15439 102 SVKEN---ILFGLPKRQASMQKMKQllAALGCQ---LDLDSSAGSLEVADRQI----VEILR--------------GLMR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 151 KfqltktlltaPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSsVQIIlvlsmlddipsFITHVIP-VDKMEVFPKVERE 229
Cdd:PRK15439 158 D----------SRILILDEPTASLTPAETERLFSRIRELLAQG-VGIV-----------FISHKLPeIRQLADRISVMRD 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 230 AY------LDAFRDRDI---------AVSFDELQKRIIDLPydGNNydsdevvklnKVSIRydDRTILN----------E 284
Cdd:PRK15439 216 GTialsgkTADLSTDDIiqaitpaarEKSLSASQKLWLELP--GNR----------RQQAA--GAPVLTvedltgegfrN 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 285 LDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFGRKRGTGESIW----EIKK-------HIGYVS-PEMH 352
Cdd:PRK15439 282 ISLEVRAGEILGLAGVVGAGRTELAE--------------TLYGLRPARGGRIMlngkEINAlstaqrlARGLVYlPEDR 347
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 353 RAYLKNL--PAIEIVASGLHDSIGLYKRPQPEQmAVCEWWMDIFGIA-GLKDKPFLQLSSGEQRLALLARAFVKDPELLI 429
Cdd:PRK15439 348 QSSGLYLdaPLAWNVCALTHNRRGFWIKPAREN-AVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLI 426
|
490 500
....*....|....*....|.
gi 2469828120 430 LDEPLHGLDTYNRRRVKKVIE 450
Cdd:PRK15439 427 VDEPTRGVDVSARNDIYQLIR 447
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
276-474 |
4.34e-09 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 58.70 E-value: 4.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 276 YDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLV-------------------------------CADNPQSYACDI 324
Cdd:PRK11174 360 PDGKTLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALlgflpyqgslkingielreldpeswrkhlswVGQNPQLPHGTL 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 325 S---LFGRKRGTGESIWEIkkhigyvspeMHRAYLKNLpaIEIVASGLHDSIGlykrpqpEQMAvcewwmdifgiaglkd 401
Cdd:PRK11174 440 RdnvLLGNPDASDEQLQQA----------LENAWVSEF--LPLLPQGLDTPIG-------DQAA---------------- 484
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 402 kpflQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAfcKRKDKTMIMVTHYESELP--DTI 474
Cdd:PRK11174 485 ----GLSVGQaQRLAL-ARALLQPCQLLLLDEPTASLDAHSEQLVMQALNA--ASRRQTTLMVTHQLEDLAqwDQI 553
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
265-465 |
4.53e-09 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 57.16 E-value: 4.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 265 EVVKLNkvsIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADNPQSYACDISLFGRKRGTGE-SIWE 339
Cdd:PRK14267 6 ETVNLR---VYYGSNHVIKGVDLKIPQNGVFALMGPSGCGKSTLLRtfnrLLELNEEARVEGEVRLFGRNIYSPDvDPIE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIG----YVSPEMHRAYLKNLpAIEIVASGLhdsiglyKRPQPEQMAVCEW-------WMDIFGiaGLKDKPFlQLS 408
Cdd:PRK14267 83 VRREVGmvfqYPNPFPHLTIYDNV-AIGVKLNGL-------VKSKKELDERVEWalkkaalWDEVKD--RLNDYPS-NLS 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 409 SGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIeaFCKRKDKTMIMVTH 465
Cdd:PRK14267 152 GGQRQRLVIARALAMKPKILLMDEPTANIDPVGTAKIEELL--FELKKEYTIVLVTH 206
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
288-465 |
4.63e-09 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 57.03 E-value: 4.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 288 TVRRGEKWALSGENGAGKSTLLSLvcadnpqsyacdisLFGR-KRGTGESIWEIKKhIGYvSPEmhraYLKnlPAIEIVA 366
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKM--------------LAGVlKPDEGDIEIELDT-VSY-KPQ----YIK--ADYEGTV 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 367 SGLHDSI--GLYKRPQpeqmavceWWMDI---FGIAGLKDKPFLQLSSGE-QRLALLArAFVKDPELLILDEPLHGLDTY 440
Cdd:cd03237 79 RDLLSSItkDFYTHPY--------FKTEIakpLQIEQILDREVPELSGGElQRVAIAA-CLSKDADIYLLDEPSAYLDVE 149
|
170 180
....*....|....*....|....*
gi 2469828120 441 NRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:cd03237 150 QRLMASKVIRRFAENNEKTAFVVEH 174
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
19-201 |
4.65e-09 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 56.98 E-value: 4.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD-----------------FFPSATQ-----TVYD 76
Cdd:COG1120 15 PVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDgrdlaslsrrelarriaYVPQEPPapfglTVRE 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 77 NVKY--IAFRDTYGaadanyyyqqRWNAHDQDEtpdVREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQL 154
Cdd:COG1120 95 LVALgrYPHLGLFG----------RPSAEDREA---VEEAL-------------ERTGLEHLADRPVDELSGGERQRVLI 148
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 155 TKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVL 201
Cdd:COG1120 149 ARALAQEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVL 195
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
266-472 |
4.85e-09 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 57.30 E-value: 4.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRT-ILNELDWTVRRGEKWALSGENGAGKSTL-LSLVCADNPQSYACDISlfGRKRGTGESIWEIKKH 343
Cdd:PRK13644 1 MIRLENVSYSYPDGTpALENINLVIKKGEYIGIIGKNGSGKSTLaLHLNGLLRPQKGKVLVS--GIDTGDFSKLQGIRKL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 IGYV--SPEMH---RAYLKN---------LPAIEIvasglhdsiglYKRPqpeQMAVCEwwmdiFGIAGLKDKPFLQLSS 409
Cdd:PRK13644 79 VGIVfqNPETQfvgRTVEEDlafgpenlcLPPIEI-----------RKRV---DRALAE-----IGLEKYRHRSPKTLSG 139
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 410 GEQRLALLARAFVKDPELLILDEPLHGLDTYN----RRRVKKVieafcKRKDKTMIMVTHYESELPD 472
Cdd:PRK13644 140 GQGQCVALAGILTMEPECLIFDEVTSMLDPDSgiavLERIKKL-----HEKGKTIVYITHNLEELHD 201
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
22-191 |
5.03e-09 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 55.48 E-value: 5.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAtqtvydnvkyiafrdtygaadanyyyqqrwn 101
Cdd:cd03230 17 DDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIK------------------------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 102 ahdqDETPDVREMLGEIKDEqlkNELFELFRIEPLLDkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTREL 181
Cdd:cd03230 66 ----KEPEEVKRRIGYLPEE---PSLYENLTVRENLK-----LSGGMKQRLALAQALLHDPELLILDEPTSGLDPESRRE 133
|
170
....*....|
gi 2469828120 182 LFSLLERLTK 191
Cdd:cd03230 134 FWELLRELKK 143
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
288-465 |
5.78e-09 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 56.86 E-value: 5.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 288 TVRRGEKWALSGENGAGKSTLLSlvCADNPQSYACDISLFGRKRGTgesiweikkhigYVSPEM--HRAYLK-------N 358
Cdd:PRK03695 18 EVRAGEILHLVGPNGAGKSTLLA--RMAGLLPGSGSIQFAGQPLEA------------WSAAELarHRAYLSqqqtppfA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 LPAIEIVAsgLHdsiglykrpQPEQMAVCEWWMDIFGIA---GLKDK---PFLQLSSGE-QRLALLARAFVKDPE----- 426
Cdd:PRK03695 84 MPVFQYLT--LH---------QPDKTRTEAVASALNEVAealGLDDKlgrSVNQLSGGEwQRVRLAAVVLQVWPDinpag 152
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 427 -LLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMIMVTH 465
Cdd:PRK03695 153 qLLLLDEPMNSLDVAQQAALDRLLSELC-QQGIAVVMSSH 191
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
22-201 |
6.16e-09 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 55.40 E-value: 6.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPsaTQTVYDNV-KYIAFrdtygaadanyyYQQRw 100
Cdd:cd03247 19 KNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQQGEITLDGVP--VSDLEKALsSLISV------------LNQR- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 101 nAHDQDETpdVREMLGEikdeqlknelfelfrieplldkkiiLLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTR- 179
Cdd:cd03247 84 -PYLFDTT--LRNNLGR-------------------------RFSGGERQRLALARILLQDAPIVLLDEPTVGLDPITEr 135
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 180 ---ELLFSLLE---------RLTKMSSVQIILVL 201
Cdd:cd03247 136 qllSLIFEVLKdktliwithHLTGIEHMDKILFL 169
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
262-465 |
6.49e-09 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 56.33 E-value: 6.49e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRY---DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVcaDN---PQSyacdislfgrkrgtGE 335
Cdd:cd03248 7 HLKGIVKFQNVTFAYptrPDTLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALL--ENfyqPQG--------------GQ 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 SIWEIKKHIGYVSPEMHR--AYLKNLPAIeiVASGLHDSIGlYKRPQPEQMAVCE----WWMDIFgIAGLKDKPFL---- 405
Cdd:cd03248 71 VLLDGKPISQYEHKYLHSkvSLVGQEPVL--FARSLQDNIA-YGLQSCSFECVKEaaqkAHAHSF-ISELASGYDTevge 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 406 ---QLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIeaFCKRKDKTMIMVTH 465
Cdd:cd03248 147 kgsQLSGGQkQRVAI-ARALIRNPQVLILDEATSALDAESEQQVQQAL--YDWPERRTVLVIAH 207
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
226-465 |
1.10e-08 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 57.51 E-value: 1.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 226 VEReayLDAFRDrdiavSFDELQKRIIDLPydGNNYDSDEVVKLNKVSIR-YDDRTILNELDWTVRRGEKWALSGENGAG 304
Cdd:COG4178 332 VDR---LAGFEE-----ALEAADALPEAAS--RIETSEDGALALEDLTLRtPDGRPLLEDLSLSLKPGERLLITGPSGSG 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 305 KSTLLslvcadnpqsyacdislfgrkR--------GTGesiweikkHIGYvsPEMH-------RAYLknlpaieIVASgL 369
Cdd:COG4178 402 KSTLL---------------------RaiaglwpyGSG--------RIAR--PAGArvlflpqRPYL-------PLGT-L 442
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 370 HDSIgLYkrPQPEQM---AVCEWWMDIFGIAGLKDKPFLQ------LSSGE-QRLAlLARAFVKDPELLILDEPLHGLDT 439
Cdd:COG4178 443 REAL-LY--PATAEAfsdAELREALEAVGLGHLAERLDEEadwdqvLSLGEqQRLA-FARLLLHKPDWLFLDEATSALDE 518
|
250 260
....*....|....*....|....*.
gi 2469828120 440 YNRRRVKKVIEAFCkrKDKTMIMVTH 465
Cdd:COG4178 519 ENEAALYQLLREEL--PGTTVISVGH 542
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
267-468 |
1.31e-08 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 54.08 E-value: 1.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLslvcadnpqsyacdislfgrkRGTGEsIWEIKK-HI 344
Cdd:cd03223 1 IELENLSLATpDGRVLLKDLSFEIKPGDRLLITGPSGTGKSSLF---------------------RALAG-LWPWGSgRI 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYvsPEMHRAYLknLPAIEIVASG-LHDSIgLYkrpqPeqmavcewWMDIfgiaglkdkpflqLSSGE-QRLALlARAFV 422
Cdd:cd03223 59 GM--PEGEDLLF--LPQRPYLPLGtLREQL-IY----P--------WDDV-------------LSGGEqQRLAF-ARLLL 107
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCkrkdKTMIMVTHYES 468
Cdd:cd03223 108 HKPKFVFLDEATSALDEESEDRLYQLLKELG----ITVISVGHRPS 149
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
282-465 |
1.59e-08 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 55.82 E-value: 1.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADNPQSYACDISLFGRKrgtgESIWEIKKHIGYV--SPEmHRAY 355
Cdd:PRK13637 23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQhlngLLKPTSGKIIIDGVDITDKK----VKLSDIRKKVGLVfqYPE-YQLF 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 356 -----------LKNLpaieivasGLHDSiGLYKRPQPEqmavcewwMDIFGIA--GLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:PRK13637 98 eetiekdiafgPINL--------GLSEE-EIENRVKRA--------MNIVGLDyeDYKDKSPFELSGGQKRRVAIAGVVA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13637 161 MEPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSH 203
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
269-485 |
1.59e-08 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 55.30 E-value: 1.59e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIR-----YDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLvcadnpqsYACDISLFGRKRGTGE-------- 335
Cdd:PRK14247 1 MNKIEIRdlkvsFGQVEVLDGVNLEIPDNTITALMGPSGSGKSTLLRV--------FNRLIELYPEARVSGEvyldgqdi 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 ---SIWEIKKHIGYV----SPemhrayLKNLPAIEIVASGLHDSIGLYKRPQPEQ-----MAVCEWWMDIfgiaglKDK- 402
Cdd:PRK14247 73 fkmDVIELRRRVQMVfqipNP------IPNLSIFENVALGLKLNRLVKSKKELQErvrwaLEKAQLWDEV------KDRl 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 403 --PFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTHYESELPDTITNRIFL 480
Cdd:PRK14247 141 daPAGKLSGGQQQRLCIARALAFQPEVLLADEPTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARISDYVAFL 218
|
....*
gi 2469828120 481 KRNQV 485
Cdd:PRK14247 219 YKGQI 223
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
27-189 |
1.72e-08 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 55.11 E-value: 1.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPlregtlqydffPSATQTVYDNVKyIAFRDTYGAADanyyYQQRwnahdqd 106
Cdd:cd03237 21 SISESEVIGILGPNGIGKTTFIKMLAGVLK-----------PDEGDIEIELDT-VSYKPQYIKAD----YEGT------- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 107 etpdVREMLGEIKDE-----QLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTREL 181
Cdd:cd03237 78 ----VRDLLSSITKDfythpYFKTEIAKPLQIEQILDREVPELSGGELQRVAIAACLSKDADIYLLDEPSAYLDVEQRLM 153
|
....*...
gi 2469828120 182 LFSLLERL 189
Cdd:cd03237 154 ASKVIRRF 161
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
267-474 |
1.96e-08 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 56.19 E-value: 1.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNpqsyacDIS----LFGRKRGTgeSIWEIKK 342
Cdd:PRK11000 4 VTLRNVTKAYGDVVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLE------DITsgdlFIGEKRMN--DVPPAER 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSPEMhrAYLKNLPAIEIVASGLH----DSIGLYKRPqpEQMAvcewwmDIFGIAGLKDKPFLQLSSGE-QRLALl 417
Cdd:PRK11000 76 GVGMVFQSY--ALYPHLSVAENMSFGLKlagaKKEEINQRV--NQVA------EVLQLAHLLDRKPKALSGGQrQRVAI- 144
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE---LPDTI 474
Cdd:PRK11000 145 GRTLVAEPSVFLLDEPLSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEamtLADKI 204
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
262-469 |
1.97e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 55.53 E-value: 1.97e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 262 DSDEVVKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSL-VCADNPQSYACdisLFGRKRGTGESIW 338
Cdd:PRK13648 3 DKNSIIVFKNVSFQYqsDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLmIGIEKVKSGEI---FYNNQAITDDNFE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGYVSPEMHRAYLKNLPAIEiVASGLHDSIGLYKRPQPEqmaVCEWWMDIFGIAGLKDKPFlQLSSGE-QRLAlL 417
Cdd:PRK13648 80 KLRKHIGIVFQNPDNQFVGSIVKYD-VAFGLENHAVPYDEMHRR---VSEALKQVDMLERADYEPN-ALSGGQkQRVA-I 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESE 469
Cdd:PRK13648 154 AGVLALNPSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSE 205
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
24-474 |
2.16e-08 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 56.37 E-value: 2.16e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPlrEGTLQYDFFPSATQTVYDNVkyiafRDTYGAADA----------- 92
Cdd:TIGR02633 20 IDLEVRPGECVGLCGENGAGKSTLMKILSGVYP--HGTWDGEIYWSGSPLKASNI-----RDTERAGIViihqeltlvpe 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 93 ----------NYYYQQRWNAHDQDETPDVREMLGEIKDEQLKNELfelfriePLLDkkiilLSSGELRKFQLTKTLLTAP 162
Cdd:TIGR02633 93 lsvaeniflgNEITLPGGRMAYNAMYLRAKNLLRELQLDADNVTR-------PVGD-----YGGGQQQLVEIAKALNKQA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 163 RVLIMDNPFIGLDAPTRELLFSLLERLtKMSSVQIILVLSMLDDIPSFithvipVDKMEVFPKVEREAYLDAfRDRDIAV 242
Cdd:TIGR02633 161 RLLILDEPSSSLTEKETEILLDIIRDL-KAHGVACVYISHKLNEVKAV------CDTICVIRDGQHVATKDM-STMSEDD 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 243 SFDELQKRIIDLPYDGNNYD-SDEVVKLNKVSIRYDD---RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQ 318
Cdd:TIGR02633 233 IITMMVGREITSLYPHEPHEiGDVILEARNLTCWDVInphRKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFGAYPG 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 319 SYACDISLFGRKRGTGESIWEIKKHIGYVSPEMHRAYLknlpaIEIVASGLHDSIGLYKR--------PQPEQMAVCEww 390
Cdd:TIGR02633 313 KFEGNVFINGKPVDIRNPAQAIRAGIAMVPEDRKRHGI-----VPILGVGKNITLSVLKSfcfkmridAAAELQIIGS-- 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 391 mdifGIAGLKDK---PFL---QLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMIMVT 464
Cdd:TIGR02633 386 ----AIQRLKVKtasPFLpigRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLA-QEGVAIIVVS 460
|
490
....*....|
gi 2469828120 465 hyeSELPDTI 474
Cdd:TIGR02633 461 ---SELAEVL 467
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
267-484 |
2.42e-08 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 54.01 E-value: 2.42e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDR-----TILNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFGRKRGTGESIwEIK 341
Cdd:cd03250 1 ISVEDASFTWDSGeqetsFTLKDINLEVPKGELVAIVGPVGSGKSSLLS--------------ALLGELEKLSGSV-SVP 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 KHIGYVS---------------------PEMHRAYLKN---LPAIEIVASGLHDSIGlykrpqpEQmavcewwmdifGIA 397
Cdd:cd03250 66 GSIAYVSqepwiqngtirenilfgkpfdEERYEKVIKAcalEPDLEILPDGDLTEIG-------EK-----------GIN 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 398 glkdkpflqLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRV-KKVIeafCK--RKDKTMIMVTHYESELP-- 471
Cdd:cd03250 128 ---------LSGGQkQRISL-ARAVYSDADIYLLDDPLSAVDAHVGRHIfENCI---LGllLNNKTRILVTHQLQLLPha 194
|
250
....*....|...
gi 2469828120 472 DTItnrIFLKRNQ 484
Cdd:cd03250 195 DQI---VVLDNGR 204
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
296-465 |
2.71e-08 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 55.49 E-value: 2.71e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 296 ALSGENGAGKSTLLSLVcA--DNPQSyaCDISLFGR-----KRGTGESIWeiKKHIGYVSPEmhrAYL-------KNLpa 361
Cdd:COG4148 29 ALFGPSGSGKTTLLRAI-AglERPDS--GRIRLGGEvlqdsARGIFLPPH--RRRIGYVFQE---ARLfphlsvrGNL-- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 362 ieivASGLHDSIGLYKRPQPEQmaVCEWwmdiFGIAGLKDKPFLQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTY 440
Cdd:COG4148 99 ----LYGRKRAPRAERRISFDE--VVEL----LGIGHLLDRRPATLSGGErQRVAI-GRALLSSPRLLLMDEPLAALDLA 167
|
170 180
....*....|....*....|....*
gi 2469828120 441 NRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG4148 168 RKAEILPYLERLRDELDIPILYVSH 192
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
22-198 |
3.06e-08 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 53.16 E-value: 3.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFP---SATQTVYDNVKYIA-----FRDTygaadan 93
Cdd:cd03228 19 KDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLRLYDPTSGEILIDGVDlrdLDLESLRKNIAYVPqdpflFSGT------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 94 yyyqqrwnahdqdetpdVREmlgeikdeqlkNelfelfrieplldkkiiLLSSGELRKFQLTKTLLTAPRVLIMDNPFIG 173
Cdd:cd03228 92 -----------------IRE-----------N-----------------ILSGGQRQRIAIARALLRDPPILILDEATSA 126
|
170 180
....*....|....*....|....*
gi 2469828120 174 LDAPTRELLFSLLERLTKMSSVQII 198
Cdd:cd03228 127 LDPETEALILEALRALAKGKTVIVI 151
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
24-199 |
3.77e-08 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 53.91 E-value: 3.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTlqydffpsATQTVYDNVK-YIAFRDTYGaadanYYYQQRwNA 102
Cdd:cd03265 19 VSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGR--------ATVAGHDVVRePREVRRRIG-----IVFQDL-SV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 103 HDQDETPDVREMLGEI---KDEQLKNELFELFRIEPLLDKKIILL---SSGELRKFQLTKTLLTAPRVLIMDNPFIGLDA 176
Cdd:cd03265 85 DDELTGWENLYIHARLygvPGAERRERIDELLDFVGLLEAADRLVktySGGMRRRLEIARSLVHRPEVLFLDEPTIGLDP 164
|
170 180
....*....|....*....|...
gi 2469828120 177 PTRELLFSLLERLTKMSSVQIIL 199
Cdd:cd03265 165 QTRAHVWEYIEKLKEEFGMTILL 187
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
244-465 |
4.75e-08 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 54.47 E-value: 4.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 244 FDELQKRIIDLPydgNNYDSDEVVKLNKVSIRYDDRT-----ILNELDWTVRRGEKWALSGENGAGKSTLLS-------- 310
Cdd:PRK13631 2 MDYFMKKKLKVP---NPLSDDIILRVKNLYCVFDEKQenelvALNNISYTFEKNKIYFIIGNSGSGKSTLVThfngliks 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 311 ---------LVCADNPQSYACDISLFGRKRgtgESIWEIKKHIGYVS--PEMHraYLKNLPAIEI----VASGLHDSigl 375
Cdd:PRK13631 79 kygtiqvgdIYIGDKKNNHELITNPYSKKI---KNFKELRRRVSMVFqfPEYQ--LFKDTIEKDImfgpVALGVKKS--- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 376 ykrpqpEQMAVCEWWMDIFGIAG--LKDKPFlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAfC 453
Cdd:PRK13631 151 ------EAKKLAKFYLNKMGLDDsyLERSPF-GLSGGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILD-A 222
|
250
....*....|..
gi 2469828120 454 KRKDKTMIMVTH 465
Cdd:PRK13631 223 KANNKTVFVITH 234
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
22-207 |
4.77e-08 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 52.96 E-value: 4.77e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDffpsaTQTVYDNVKYIAFRDTygaaDANYYYQQrwn 101
Cdd:cd03229 17 NDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILID-----GEDLTDLEDELPPLRR----RIGMVFQD--- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 102 ahdqdetpdvremlgeikdeqlknelFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTREL 181
Cdd:cd03229 85 --------------------------FALFPHLTVLENIALGLSGGQQQRVALARALAMDPDVLLLDEPTSALDPITRRE 138
|
170 180
....*....|....*....|....*.
gi 2469828120 182 LFSLLERLTKMSSVQIILVLSMLDDI 207
Cdd:cd03229 139 VRALLKSLQAQLGITVVLVTHDLDEA 164
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
278-465 |
6.74e-08 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 54.75 E-value: 6.74e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 278 DRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQS----------YACDISLFGRkrgtgesiweikkHIGY 346
Cdd:COG4618 344 KRPILRGVSFSLEPGEVLGVIGPSGSGKSTLArLLVGVWPPTAgsvrldgadlSQWDREELGR-------------HIGY 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 V--SPEMHR-------AYLKNLPAIEIVA----SGLHDSIGlyKRPQPEQMAVcewwmdifGIAGLkdkpflQLSSGE-Q 412
Cdd:COG4618 411 LpqDVELFDgtiaeniARFGDADPEKVVAaaklAGVHEMIL--RLPDGYDTRI--------GEGGA------RLSGGQrQ 474
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 413 RLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKdKTMIMVTH 465
Cdd:COG4618 475 RIGL-ARALYGDPRLVVLDEPNSNLDDEGEAALAAAIRALKARG-ATVVVITH 525
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
263-475 |
7.04e-08 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 54.64 E-value: 7.04e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTL---LSLVcadnpqsYACD---ISLFGRK---RGT 333
Cdd:COG1129 1 AEPLLEMRGISKSFGGVKALDGVSLELRPGEVHALLGENGAGKSTLmkiLSGV-------YQPDsgeILLDGEPvrfRSP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 334 GESiweIKKHIGYVSPEMhrAYLKNLPAIE-------IVASGLHDSIGLYKRPQpeqmAVCEWWmdifgiaGLK---DKP 403
Cdd:COG1129 74 RDA---QAAGIAIIHQEL--NLVPNLSVAEniflgrePRRGGLIDWRAMRRRAR----ELLARL-------GLDidpDTP 137
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 404 FLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESE---LPDTIT 475
Cdd:COG1129 138 VGDLSVAQQQLVEIARALSRDARVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEvfeIADRVT 211
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
404-474 |
7.16e-08 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 51.98 E-value: 7.16e-08
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 404 FLQLSSGEQRLALLARAF----VKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTHYE--SELPDTI 474
Cdd:cd03227 75 RLQLSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAEAILEHLV-KGAQVIVITHLPelAELADKL 150
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
267-478 |
7.85e-08 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 54.51 E-value: 7.85e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSyacdislfgrkrgtGESIWEIKKHIG 345
Cdd:PRK15064 320 LEVENLTKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLrTLVGELEPDS--------------GTVKWSENANIG 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVsPEMHRAYLKNlpaieivASGLHDSIGLYKRPQP-EQMavcewwmdIFGIAGL----KD---KPFLQLSSGEQRLALL 417
Cdd:PRK15064 386 YY-AQDHAYDFEN-------DLTLFDWMSQWRQEGDdEQA--------VRGTLGRllfsQDdikKSVKVLSGGEKGRMLF 449
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 418 ARAFVKDPELLILDEPLHGLDTynrrrvkKVIEAF---CKRKDKTMIMVTHyESELPDTITNRI 478
Cdd:PRK15064 450 GKLMMQKPNVLVMDEPTNHMDM-------ESIESLnmaLEKYEGTLIFVSH-DREFVSSLATRI 505
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
260-465 |
7.91e-08 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 53.62 E-value: 7.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 260 NYDSDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyacdislfGRKRGTGESIW 338
Cdd:PRK11831 1 EQSVANLVDMRGVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQiAPDH--------GEILFDGENIP 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 EIKKHIGY-VSPEMHR-----AYLKNLPAIEIVASGLHDSIGLykrPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQ 412
Cdd:PRK11831 73 AMSRSRLYtVRKRMSMlfqsgALFTDMNVFDNVAYPLREHTQL---PAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMA 149
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 413 RLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK11831 150 RRAALARAIALEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSH 202
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
282-475 |
9.11e-08 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 54.53 E-value: 9.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNpQSYACDISLFGRK---RGTGESIWE----IKKHIGYVsPEMHRA 354
Cdd:PRK11288 20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSGNY-QPDAGSILIDGQEmrfASTTAALAAgvaiIYQELHLV-PEMTVA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 355 ---YLKNLPAieivASGLHDSIGLYKRPQpEQMAvcEWWMDIFGIAGLKDkpflqLSSGEQRLALLARAFVKDPELLILD 431
Cdd:PRK11288 98 enlYLGQLPH----KGGIVNRRLLNYEAR-EQLE--HLGVDIDPDTPLKY-----LSIGQRQMVEIAKALARNARVIAFD 165
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 432 EPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESE---LPDTIT 475
Cdd:PRK11288 166 EPTSSLSAREIEQLFRVIREL-RAEGRVILYVSHRMEEifaLCDAIT 211
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
271-465 |
9.13e-08 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 53.90 E-value: 9.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 271 KVSIRYDDRTI--LNELDWTVRRGEKWALSGENGAGKSTL-LSLVCADNPQsyacdislfGRKRGT----GESIWEIKKh 343
Cdd:COG0444 8 KVYFPTRRGVVkaVDGVSFDVRRGETLGLVGESGSGKSTLaRAILGLLPPP---------GITSGEilfdGEDLLKLSE- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 igyvsPEMHRAYLKNLPAI---------------EIVASGL--HdsiGLYKRPQPEQMAVcEWwMDIFGIAG----LKDK 402
Cdd:COG0444 78 -----KELRKIRGREIQMIfqdpmtslnpvmtvgDQIAEPLriH---GGLSKAEARERAI-EL-LERVGLPDperrLDRY 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 403 PFlQLSSGE-QRlALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG0444 148 PH-ELSGGMrQR-VMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITH 209
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
279-465 |
1.01e-07 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 53.15 E-value: 1.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLSLV------------CADNPQS-----------------YACDISLFGR 329
Cdd:PRK10419 25 QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLvglespsqgnvsWRGEPLAklnraqrkafrrdiqmvFQDSISAVNP 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 330 KRGTGESIWEIKKHIGYVSPEMHRAYLKNLpaieIVASGLHDSIgLYKRPQpeqmavcewwmdifgiaglkdkpflQLSS 409
Cdd:PRK10419 105 RKTVREIIREPLRHLLSLDKAERLARASEM----LRAVDLDDSV-LDKRPP-------------------------QLSG 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 410 GEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10419 155 GQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITH 210
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
24-219 |
1.02e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 53.21 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIafRDTYGAAdanyyYQqrwNAH 103
Cdd:PRK13649 26 VNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKNKDIKQI--RKKVGLV-----FQ---FPE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 104 DQ--DET--PDVR---EMLG--EIKDEQLKNELFELFRI-EPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIG 173
Cdd:PRK13649 96 SQlfEETvlKDVAfgpQNFGvsQEEAEALAREKLALVGIsESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAG 175
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 174 LDAPTRELLFSLLERLTKmSSVQIILVLSMLDDIPSFITHVIPVDK 219
Cdd:PRK13649 176 LDPKGRKELMTLFKKLHQ-SGMTIVLVTHLMDDVANYADFVYVLEK 220
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
269-465 |
1.03e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 53.47 E-value: 1.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRT-----ILNELDWTVRRGEKWALSGENGAGKSTLLSL----VCADNPQSYACDISLFGRKRGTGEsIWE 339
Cdd:PRK13645 9 LDNVSYTYAKKTpfefkALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLtnglIISETGQTIVGDYAIPANLKKIKE-VKR 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIGYVSPEMHRAYLKNLPAIEIVASGLH---DSIGLYKRpQPEQMAVCEWWMDIfgiagLKDKPFlQLSSGEQRLAL 416
Cdd:PRK13645 88 LRKEIGLVFQFPEYQLFQETIEKDIAFGPVNlgeNKQEAYKK-VPELLKLVQLPEDY-----VKRSPF-ELSGGQKRRVA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 2469828120 417 LARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13645 161 LAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTH 209
|
|
| nickel_nikE |
TIGR02769 |
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a ... |
280-465 |
1.31e-07 |
|
nickel import ATP-binding protein NikE; This family represents the NikE subunit of a multisubunit nickel import ABC transporter complex. Nickel, once imported, may be used in urease and in certain classes of hydrogenase and superoxide dismutase. [Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 131816 [Multi-domain] Cd Length: 265 Bit Score: 52.89 E-value: 1.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 280 TILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA-DNPQSyacdislfGRKRGTGESIWEIKkhigyvsPEMHRAYLKN 358
Cdd:TIGR02769 25 PVLTNVSLSIEEGETVGLLGRSGCGKSTLARLLLGlEKPAQ--------GTVSFRGQDLYQLD-------RKQRRAFRRD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 LPAI---------------EIVASGLHDSIGLYKRPQPEQMAVCewwMDIFGI-AGLKDKPFLQLSSGEQRLALLARAFV 422
Cdd:TIGR02769 90 VQLVfqdspsavnprmtvrQIIGEPLRHLTSLDESEQKARIAEL---LDMVGLrSEDADKLPRQLSGGQLQRINIARALA 166
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 2469828120 423 KDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:TIGR02769 167 VKPKLIVLDEAVSNLDMVLQAVILELLRKLQQAFGTAYLFITH 209
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
1-478 |
1.33e-07 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 53.78 E-value: 1.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 1 MSQNTFSMAGGVARNPLVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPlrEGTLQYDFFPSATQTVYDNVky 80
Cdd:PRK13549 1 MMEYLLEMKNITKTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGVYP--HGTYEGEIIFEGEELQASNI-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 81 iafRDTYGAADAnYYYQqrwnahdqdETPDVREM-------LGE-------IKDEQLKNELFELFR-----IEPllDKKI 141
Cdd:PRK13549 77 ---RDTERAGIA-IIHQ---------ELALVKELsvlenifLGNeitpggiMDYDAMYLRAQKLLAqlkldINP--ATPV 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 142 ILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK--MSSVQIILVLSMLDDIPSFIThVI---- 215
Cdd:PRK13549 142 GNLGLGQQQLVEIAKALNKQARLLILDEPTASLTESETAVLLDIIRDLKAhgIACIYISHKLNEVKAISDTIC-VIrdgr 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 216 -----PVDKM---------------EVFPKVEREAYLDAFRDRDIAVsfdelqkriidlpYDGNNydsdevvklnkvsir 275
Cdd:PRK13549 221 higtrPAAGMteddiitmmvgreltALYPREPHTIGEVILEVRNLTA-------------WDPVN--------------- 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 276 yDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYACDISLFGRKRGTGESIWEIKKHIGYVS------- 348
Cdd:PRK13549 273 -PHIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFGAYPGRWEGEIFIDGKPVKIRNPQQAIAQGIAMVPedrkrdg 351
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 349 --PEMHRAYLKNLPAIEIVASG--LHDSIglykrpqpEQMAVCEwwmdifGIAGLKDK---PFL---QLSSGEQRLALLA 418
Cdd:PRK13549 352 ivPVMGVGKNITLAALDRFTGGsrIDDAA--------ELKTILE------SIQRLKVKtasPELaiaRLSGGNQQKAVLA 417
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 419 RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVThyeSELPDT--ITNRI 478
Cdd:PRK13549 418 KCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQ-GVAIIVIS---SELPEVlgLSDRV 475
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
278-472 |
1.53e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 52.88 E-value: 1.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 278 DRTILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSYACDIslfgrkRG---TGESIWEIKKHIGYVspemhr 353
Cdd:PRK13652 16 SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRhFNGILKPTSGSVLI------RGepiTKENIREVRKFVGLV------ 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 354 ayLKNlPAIEIVASGLHDSIGLykrpQPEQMAV--------CEWWMDIFGIAGLKDKPFLQLSSGEQRLALLARAFVKDP 425
Cdd:PRK13652 84 --FQN-PDDQIFSPTVEQDIAF----GPINLGLdeetvahrVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEP 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPD 472
Cdd:PRK13652 157 QVLVLDEPTAGLDPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPE 203
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
20-182 |
1.62e-07 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 50.52 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 20 LAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDffpsatqtvyDNVKYiafrdtygaadanYYYQQr 99
Cdd:cd03221 15 LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG----------STVKI-------------GYFEQ- 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 100 wnahdqdetpdvremlgeikdeqlknelfelfrieplldkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTR 179
Cdd:cd03221 71 --------------------------------------------LSGGEKMRLALAKLLLENPNLLLLDEPTNHLDLESI 106
|
...
gi 2469828120 180 ELL 182
Cdd:cd03221 107 EAL 109
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
282-475 |
1.67e-07 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 53.64 E-value: 1.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTL---LSLVcadNPQ-SYACDISLFG---RKRGTGESiweikKHIGYV------- 347
Cdd:NF040905 17 LDDVNLSVREGEIHALCGENGAGKSTLmkvLSGV---YPHgSYEGEILFDGevcRFKDIRDS-----EALGIViihqela 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 -SPEMHRA---YLKNlpaiEIVASGLHDSIGLYKRPQpEQMAvcewwmdifgIAGLKDKPFLQLSS---GEQRLALLARA 420
Cdd:NF040905 89 lIPYLSIAeniFLGN----ERAKRGVIDWNETNRRAR-ELLA----------KVGLDESPDTLVTDigvGKQQLVEIAKA 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHYESEL---PDTIT 475
Cdd:NF040905 154 LSKDVKLLILDEPTAALNEEDSAALLDLLLEL-KAQGITSIIISHKLNEIrrvADSIT 210
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
267-485 |
1.72e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 52.86 E-value: 1.72e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRT-----ILNELDWTVRRGEKWALSGENGAGKSTLL----SLVCADNPQSYACDISLFGRKRGtgESI 337
Cdd:PRK13646 3 IRFDNVSYTYQKGTpyehqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIqninALLKPTTGTVTVDDITITHKTKD--KYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 WEIKKHIGYVS--PE-------MHRAYL---KNLPA-IEIVASGLHDSIglykrpqpeqmavcewwMDI-FGIAGLKDKP 403
Cdd:PRK13646 81 RPVRKRIGMVFqfPEsqlfedtVEREIIfgpKNFKMnLDEVKNYAHRLL-----------------MDLgFSRDVMSQSP 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 404 FlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLKRN 483
Cdd:PRK13646 144 F-QMSGGQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEG 222
|
..
gi 2469828120 484 QV 485
Cdd:PRK13646 223 SI 224
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
403-465 |
1.88e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 52.71 E-value: 1.88e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 403 PFlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK13634 143 PF-ELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTH 204
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
267-465 |
2.03e-07 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 51.73 E-value: 2.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSlvcadnpqsyacdiSLFGRKRGTGESIW----EI 340
Cdd:cd03244 3 IEFKNVSLRYrpNLPPVLKNISFSIKPGEKVGIVGRTGSGKSSLLL--------------ALFRLVELSSGSILidgvDI 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 341 KKhigyVSPEMHRAYLKNLPAIEIVASG-LHDSIGLYKRPQPEQMavcewwMDIFGIAGLKD----KPF----------L 405
Cdd:cd03244 69 SK----IGLHDLRSRISIIPQDPVLFSGtIRSNLDPFGEYSDEEL------WQALERVGLKEfvesLPGgldtvveeggE 138
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 406 QLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI-EAFckrKDKTMIMVTH 465
Cdd:cd03244 139 NLSVGQRQLLCLARALLRKSKILVLDEATASVDPETDALIQKTIrEAF---KDCTVLTIAH 196
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
282-478 |
2.09e-07 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 50.89 E-value: 2.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQsYACDISLFGrKRGTGESIWE-IKKHIGYVSPEMHRaylknlp 360
Cdd:cd03215 16 VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPP-ASGEITLDG-KPVTRRSPRDaIRAGIAYVPEDRKR------- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 361 aieivaSGLHDSiglykrpqpeqmavcewwMDIFGIAGLKDkpflQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTY 440
Cdd:cd03215 87 ------EGLVLD------------------LSVAENIALSS----LLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVG 138
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 441 NRRRVKKVIEAFcKRKDKTMIMVThyeSELPD--TITNRI 478
Cdd:cd03215 139 AKAEIYRLIREL-ADAGKAVLLIS---SELDEllGLCDRI 174
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
118-228 |
2.21e-07 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 52.36 E-value: 2.21e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 118 IKDEQLKNELFELFRI-----EPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKM 192
Cdd:PRK13637 114 LSEEEIENRVKRAMNIvgldyEDYKDKSPFELSGGQKRRVAIAGVVAMEPKILILDEPTAGLDPKGRDEILNKIKELHKE 193
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 2469828120 193 SSVQIILVLSMLDDIPSFITHVIPVDK---------MEVFPKVER 228
Cdd:PRK13637 194 YNMTIILVSHSMEDVAKLADRIIVMNKgkcelqgtpREVFKEVET 238
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
19-210 |
2.29e-07 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 51.96 E-value: 2.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLR-----EGTLQY--------------------------DFF 67
Cdd:PRK14258 21 KILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMNELEsevrvEGRVEFfnqniyerrvnlnrlrrqvsmvhpkpNLF 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 68 PsatQTVYDNVkyiafrdTYGAADANYyyqqrwnaHDQDETPDVREmlGEIKDEQLKNElfelfrIEPLLDKKIILLSSG 147
Cdd:PRK14258 101 P---MSVYDNV-------AYGVKIVGW--------RPKLEIDDIVE--SALKDADLWDE------IKHKIHKSALDLSGG 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 148 ELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV------LSMLDDIPSF 210
Cdd:PRK14258 155 QQQRLCIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVshnlhqVSRLSDFTAF 223
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
279-485 |
2.48e-07 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 53.13 E-value: 2.48e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 279 RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQS--YACDISLFGRKRGTgesiWEIKKHIGYVspEMHRAYL 356
Cdd:TIGR00955 38 KHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGvkGSGSVLLNGMPIDA----KEMRAISAYV--QQDDLFI 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 357 KNLPAIE--IVASGL--HDSIGLYKRPQP-----EQMAVCEWWMDIFGIAGLKDKpflqLSSGE-QRLALlARAFVKDPE 426
Cdd:TIGR00955 112 PTLTVREhlMFQAHLrmPRRVTKKEKRERvdevlQALGLRKCANTRIGVPGRVKG----LSGGErKRLAF-ASELLTDPP 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 427 LLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTHY-ESELPDTITNRIFLKRNQV 485
Cdd:TIGR00955 187 LLFCDEPTSGLDSFMAYSVVQVLKGLAQ-KGKTIICTIHQpSSELFELFDKIILMAEGRV 245
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
24-186 |
2.59e-07 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 50.95 E-value: 2.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQ--TVYDNVKYIAFRD---TYGAADANYYYQQ 98
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGGPLDFQrdSIARGLLYLGHAPgikTTLSVLENLRFWH 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 99 RWNAHDQDETPDVREMLGEIKDEQLKNelfelfrieplldkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPT 178
Cdd:cd03231 99 ADHSDEQVEEALARVGLNGFEDRPVAQ------------------LSAGQQRRVALARLLLSGRPLWILDEPTTALDKAG 160
|
....*...
gi 2469828120 179 RELLFSLL 186
Cdd:cd03231 161 VARFAEAM 168
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
34-207 |
3.13e-07 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 50.63 E-value: 3.13e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 34 IAIVGPNGGGKSLFVDTLTGK--YPLREGTLQYDFFPSatqtvydnvKYIAFRDTYGaadanyYYQQrwnaHDQ-DETPD 110
Cdd:cd03213 38 TAIMGPSGAGKSTLLNALAGRrtGLGVSGEVLINGRPL---------DKRSFRKIIG------YVPQ----DDIlHPTLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 111 VREMLGEIKdeQLKNelfelfrieplldkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLT 190
Cdd:cd03213 99 VRETLMFAA--KLRG------------------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLA 158
|
170 180
....*....|....*....|....
gi 2469828120 191 KMSSVQII-------LVLSMLDDI 207
Cdd:cd03213 159 DTGRTIICsihqpssEIFELFDKL 182
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
35-478 |
3.29e-07 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 52.61 E-value: 3.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 35 AIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPsatqtvydnvkyIAFRDTYGAADANY--YYQqrwnahdqdETPDVR 112
Cdd:PRK11288 34 ALMGENGAGKSTLLKILSGNYQPDAGSILIDGQE------------MRFASTTAALAAGVaiIYQ---------ELHLVP 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 113 EM--------------LGEIKDEQLKNE----LFEL-FRIEPllDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIG 173
Cdd:PRK11288 93 EMtvaenlylgqlphkGGIVNRRLLNYEareqLEHLgVDIDP--DTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSS 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 174 LDAPTRELLFSLLERLTKMSSVQIilvlsmlddipsFITHvipvdKM-EVFpkvereAYLDA---FRDRDIAVSFDELQK 249
Cdd:PRK11288 171 LSAREIEQLFRVIRELRAEGRVIL------------YVSH-----RMeEIF------ALCDAitvFKDGRYVATFDDMAQ 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 250 ------------RIIDLPYDgnnYDSDEvvkLNKVSIRYDD---RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCA 314
Cdd:PRK11288 228 vdrdqlvqamvgREIGDIYG---YRPRP---LGEVRLRLDGlkgPGLREPISFSVRAGEIVGLFGLVGAGRSELMKLLYG 301
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 315 DNPQSyACDISLFGRK---RGTGESIW-------EIKKHIGYVSpemHRAYLKNlpaIEIVASGLHDSIGLYKRPQPE-Q 383
Cdd:PRK11288 302 ATRRT-AGQVYLDGKPidiRSPRDAIRagimlcpEDRKAEGIIP---VHSVADN---INISARRHHLRAGCLINNRWEaE 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 384 MAvcewwmDIFgIAGLK------DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKd 457
Cdd:PRK11288 375 NA------DRF-IRSLNiktpsrEQLIMNLSGGNQQKAILGRWLSEDMKVILLDEPTRGIDVGAKHEIYNVIYELAAQG- 446
|
490 500
....*....|....*....|...
gi 2469828120 458 KTMIMVThyeSELPDT--ITNRI 478
Cdd:PRK11288 447 VAVLFVS---SDLPEVlgVADRI 466
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
277-465 |
3.31e-07 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 51.63 E-value: 3.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAdnpqSYACD---ISLFGRKRgTGESIWEIKKHIGYV------ 347
Cdd:COG1101 17 NEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAG----SLPPDsgsILIDGKDV-TKLPEYKRAKYIGRVfqdpmm 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 --SPEM------HRAYLKNLPAieivasGLHDSIGLYKRPQ-PEQMAvcewwmdIFGIaGLKDKpfLQ----LSSGEQRL 414
Cdd:COG1101 92 gtAPSMtieenlALAYRRGKRR------GLRRGLTKKRRELfRELLA-------TLGL-GLENR--LDtkvgLLSGGQRQ 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 415 AL-LARAFVKDPELLILDEPLHGLDTynrRRVKKVIEA---FCKRKDKTMIMVTH 465
Cdd:COG1101 156 ALsLLMATLTKPKLLLLDEHTAALDP---KTAALVLELtekIVEENNLTTLMVTH 207
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
266-485 |
4.25e-07 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 51.12 E-value: 4.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKvsiRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLV-CADNPQSYAC-----DISLFGRKRGT-----G 334
Cdd:PRK10619 8 VIDLHK---RYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCInFLEKPSEGSIvvngqTINLVRDKDGQlkvadK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 335 ESIWEIKKHIGYVSpeMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQmavCEWWMDIFGIAG-LKDKPFLQLSSGEQR 413
Cdd:PRK10619 85 NQLRLLRTRLTMVF--QHFNLWSHMTVLENVMEAPIQVLGLSKQEARER---AVKYLAKVGIDErAQGKYPVHLSGGQQQ 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 414 LALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVTHyESELPDTITNR-IFLKRNQV 485
Cdd:PRK10619 160 RVSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAE-EGKTMVVVTH-EMGFARHVSSHvIFLHQGKI 230
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
277-473 |
4.35e-07 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 52.64 E-value: 4.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGRKRGTGESIW----EIKKHIGY---VSP 349
Cdd:TIGR00957 649 DLPPTLNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEG-HVHMKGSVAYVPQQAWiqndSLRENILFgkaLNE 727
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EMHRAYLKN---LPAIEIVASGLHDSIGlykrpqpeqmavcewwmdifgiaglkdKPFLQLSSGEQRLALLARAFVKDPE 426
Cdd:TIGR00957 728 KYYQQVLEAcalLPDLEILPSGDRTEIG---------------------------EKGVNLSGGQKQRVSLARAVYSNAD 780
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 427 LLILDEPLHGLDTYNRRRV-KKVIEAFCKRKDKTMIMVTHYESELPDT 473
Cdd:TIGR00957 781 IYLFDDPLSAVDAHVGKHIfEHVIGPEGVLKNKTRILVTHGISYLPQV 828
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
27-175 |
4.42e-07 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 52.50 E-value: 4.42e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTlqydffpsatqtVYDNVKyIAFRDTYGAADanyyyqqrwnahdQD 106
Cdd:PRK13409 361 EIYEGEVIGIVGPNGIGKTTFAKLLAGVLKPDEGE------------VDPELK-ISYKPQYIKPD-------------YD 414
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 107 ETpdVREMLGEIKD----EQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLD 175
Cdd:PRK13409 415 GT--VEDLLRSITDdlgsSYYKSEIIKPLQLERLLDKNVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 485
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
267-465 |
4.76e-07 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 52.33 E-value: 4.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYD--DRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCadnpQSYacDISLfGRKRGTGESIWE----- 339
Cdd:PRK11176 342 IEFRNVTFTYPgkEVPALRNINFKIPAGKTVALVGRSGSGKSTIANLLT----RFY--DIDE-GEILLDGHDLRDytlas 414
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 340 IKKHIGYVSPEMHrayLKNlpaiEIVASGL-HDSIGLYKRPQPEQMAVCEWWMDIfgIAGLKD-------KPFLQLSSGE 411
Cdd:PRK11176 415 LRNQVALVSQNVH---LFN----DTIANNIaYARTEQYSREQIEEAARMAYAMDF--INKMDNgldtvigENGVLLSGGQ 485
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 412 -QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:PRK11176 486 rQRIAI-ARALLRDSPILILDEATSALDTESERAIQAALDEL--QKNRTSLVIAH 537
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
24-200 |
5.32e-07 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 50.51 E-value: 5.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD-------------------------FFPSatQTVYDNV 78
Cdd:cd03224 19 VSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDgrditglppheraragigyvpegrrIFPE--LTVEENL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 79 KYIAFRDTYGAADANYyyqqrwnahdqdetpdvremlgeikdeqlkNELFELF-RIEPLLDKKIILLSSGElrKFQLT-- 155
Cdd:cd03224 97 LLGAYARRRAKRKARL------------------------------ERVYELFpRLKERRKQLAGTLSGGE--QQMLAia 144
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 156 KTLLTAPRVLIMDNPFIGLdAPT-RELLFSLLERLTKmSSVQIILV 200
Cdd:cd03224 145 RALMSRPKLLLLDEPSEGL-APKiVEEIFEAIRELRD-EGVTILLV 188
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
263-465 |
5.50e-07 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 51.95 E-value: 5.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADnpqsyACDISLFGRK---RGTGE 335
Cdd:COG3845 2 MPPALELRGITKRFGGVVANDDVSLTVRPGEIHALLGENGAGKSTLMKilygLYQPD-----SGEILIDGKPvriRSPRD 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 336 SiweIKKHIGYVSpeMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEwwmdifgIA---GLK---DKPFLQLSS 409
Cdd:COG3845 77 A---IALGIGMVH--QHFMLVPNLTVAENIVLGLEPTKGGRLDRKAARARIRE-------LSeryGLDvdpDAKVEDLSV 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 410 GE-QRLALLaRAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:COG3845 145 GEqQRVEIL-KALYRGARILILDEPTAVLTPQEADELFEILRRL-AAEGKSIIFITH 199
|
|
| AztA |
NF040873 |
zinc ABC transporter ATP-binding protein AztA; |
24-190 |
6.37e-07 |
|
zinc ABC transporter ATP-binding protein AztA;
Pssm-ID: 468810 [Multi-domain] Cd Length: 191 Bit Score: 49.54 E-value: 6.37e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQY----------------DFFPSatqTVYDNVKYIAFRDty 87
Cdd:NF040873 11 VDLTIPAGSLTAVVGPNGSGKSTLLKVLAGVLRPTSGTVRRaggarvayvpqrsevpDSLPL---TVRDLVAMGRWAR-- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 88 gaadanyyyQQRWNAHDQDETPDVREMLgeikdeqlknelfELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIM 167
Cdd:NF040873 86 ---------RGLWRRLTRDDRAAVDDAL-------------ERVGLADLAGRQLGELSGGQRQRALLAQGLAQEADLLLL 143
|
170 180
....*....|....*....|...
gi 2469828120 168 DNPFIGLDAPTRELLFSLLERLT 190
Cdd:NF040873 144 DEPTTGLDAESRERIIALLAEEH 166
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
267-438 |
7.75e-07 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 51.49 E-value: 7.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQS-----YACDISLfGR-----KRGTGES 336
Cdd:PRK11147 4 ISIHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGEVLLDdgriiYEQDLIV-ARlqqdpPRNVEGT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 337 IWEikkhigYVSPEM-HRA-YLKNLPAIeivasgLHDSIGLYKRPQPEQMAVCE--------WWMD-----IFGIAGLK- 400
Cdd:PRK11147 83 VYD------FVAEGIeEQAeYLKRYHDI------SHLVETDPSEKNLNELAKLQeqldhhnlWQLEnrineVLAQLGLDp 150
|
170 180 190
....*....|....*....|....*....|....*...
gi 2469828120 401 DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLD 438
Cdd:PRK11147 151 DAALSSLSGGWLRKAALGRALVSNPDVLLLDEPTNHLD 188
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
407-485 |
7.78e-07 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 51.34 E-value: 7.78e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 407 LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:TIGR03269 169 LSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLSDKAIWLENGEI 247
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
281-465 |
8.12e-07 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 51.65 E-value: 8.12e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 281 ILNELDWTVRRGEKWALSGENGAGKSTLLS-LVCADNPQSyacdislfGRKRGTGESIWEI---------KKHIGYVSPE 350
Cdd:PRK10535 23 VLKGISLDIYAGEMVAIVGASGSGKSTLMNiLGCLDKPTS--------GTYRVAGQDVATLdadalaqlrREHFGFIFQR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 MHraYLKNLPA---IEIVAsgLHDSIGLYKRPQPEQMAVCEwwmdiFGIAGLKDKPFLQLSSGEQRLALLARAFVKDPEL 427
Cdd:PRK10535 95 YH--LLSHLTAaqnVEVPA--VYAGLERKQRLLRAQELLQR-----LGLEDRVEYQPSQLSGGQQQRVSIARALMNGGQV 165
|
170 180 190
....*....|....*....|....*....|....*...
gi 2469828120 428 LILDEPLHGLDTYNRRRVKKVIEAFCKRkDKTMIMVTH 465
Cdd:PRK10535 166 ILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTH 202
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
13-255 |
8.57e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 50.40 E-value: 8.57e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 13 ARNPLVRLA-KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD-----------------------F-F 67
Cdd:PRK13634 14 YKTPFERRAlYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGervitagkknkklkplrkkvgivFqF 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 68 PSAT---QTVydnVKYIAFrdtyGAadanyyyqQRWNAHDQDETPDVREMLGEIKDEqlknelfelfriEPLLDKKIILL 144
Cdd:PRK13634 94 PEHQlfeETV---EKDICF----GP--------MNFGVSEEDAKQKAREMIELVGLP------------EELLARSPFEL 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 145 SSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDKMEVFP 224
Cdd:PRK13634 147 SGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFL 226
|
250 260 270
....*....|....*....|....*....|..
gi 2469828120 225 K-VEREAYLDAfrdrdiavsfDELQKRIIDLP 255
Cdd:PRK13634 227 QgTPREIFADP----------DELEAIGLDLP 248
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
266-465 |
9.19e-07 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 51.32 E-value: 9.19e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSyaCDISLfgrKRGtgesiweIKkhI 344
Cdd:PRK10636 312 LLKMEKVSAGYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGElAPVS--GEIGL---AKG-------IK--L 377
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSpeMHRayLKNLPAIEivaSGLHDSIGLYKRPQPEQMavcEWWMDIFGIAGLK-DKPFLQLSSGEQRLALLARAFVK 423
Cdd:PRK10636 378 GYFA--QHQ--LEFLRADE---SPLQHLARLAPQELEQKL---RDYLGGFGFQGDKvTEETRRFSGGEKARLVLALIVWQ 447
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2469828120 424 DPELLILDEPLHGLDTYNRRRVKKVIEAFckrkDKTMIMVTH 465
Cdd:PRK10636 448 RPNLLLLDEPTNHLDLDMRQALTEALIDF----EGALVVVSH 485
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
24-222 |
9.50e-07 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 50.19 E-value: 9.50e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLqydfFPSATQTVYDNVKYIafRDTYGAAdanyyYQqrwNAH 103
Cdd:PRK13652 23 INFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSV----LIRGEPITKENIREV--RKFVGLV-----FQ---NPD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 104 DQDETPDVRE---------MLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGL 174
Cdd:PRK13652 89 DQIFSPTVEQdiafgpinlGLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 175 DAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDKMEV 222
Cdd:PRK13652 169 DPQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRI 216
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
263-465 |
9.68e-07 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 50.37 E-value: 9.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 263 SDEVVKL--NKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSyacdislfGRKRGTGESIW- 338
Cdd:PRK10253 2 TESVARLrgEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLrTLSRLMTPAH--------GHVWLDGEHIQh 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 339 ----EIKKHIGYVSpeMHRAYLKNLPAIEIVASGLHDSIGLYKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLSSGEQRL 414
Cdd:PRK10253 74 yaskEVARRIGLLA--QNATTPGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQR 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 415 ALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10253 152 AWIAMVLAQETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLH 202
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
27-189 |
9.92e-07 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 50.60 E-value: 9.92e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTvydnvkyiafrdtyGAADANYYYQQRWNAHDQD 106
Cdd:PRK13536 63 TVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLGVPVPARA--------------RLARARIGVVPQFDNLDLE 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 107 ETpdVREML---------GEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAP 177
Cdd:PRK13536 129 FT--VRENLlvfgryfgmSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQLLILDEPTTGLDPH 206
|
170
....*....|..
gi 2469828120 178 TRELLFSLLERL 189
Cdd:PRK13536 207 ARHLIWERLRSL 218
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
5-252 |
1.01e-06 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 50.17 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 5 TFSMAGGVARNPLVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPlregtlqydffPSATQTVYDNVKYiafr 84
Cdd:PRK15112 13 TFRYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIE-----------PTSGELLIDDHPL---- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 85 dTYGaadaNYYYQ-QRWNAHDQDETPDV--REMLGEIKD-----------EQLKNELFELFRIEPLLDKKII----LLSS 146
Cdd:PRK15112 78 -HFG----DYSYRsQRIRMIFQDPSTSLnpRQRISQILDfplrlntdlepEQREKQIIETLRQVGLLPDHASyyphMLAP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 147 GELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV---LSMLDDIPSfitHVIPVDKMEVf 223
Cdd:PRK15112 153 GQKQRLGLARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVtqhLGMMKHISD---QVLVMHQGEV- 228
|
250 260
....*....|....*....|....*....
gi 2469828120 224 pkVEREAYLDAfrdrdIAVSFDELQKRII 252
Cdd:PRK15112 229 --VERGSTADV-----LASPLHELTKRLI 250
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
22-215 |
1.08e-06 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 50.08 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTA----TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFF----PSATQ-TVYDNVKYIAFRDtygaADA 92
Cdd:PRK11248 14 KPALEdinlTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKpvegPGAERgVVFQNEGLLPWRN----VQD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 93 NYYYQQRWNAHDQDETPDV-REMLGEIKDEQLKNelfelfrieplldKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPF 171
Cdd:PRK11248 90 NVAFGLQLAGVEKMQRLEIaHQMLKKVGLEGAEK-------------RYIWQLSGGQRQRVGIARALAANPQLLLLDEPF 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2469828120 172 IGLDAPTRELLFSLLERLTKMSSVQIILvlsmlddipsfITHVI 215
Cdd:PRK11248 157 GALDAFTREQMQTLLLKLWQETGKQVLL-----------ITHDI 189
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
267-465 |
1.37e-06 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 49.63 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLL-SLVCADNPQSYACDI--SLFGRKRGTGES-IWEIKK 342
Cdd:PRK11124 3 IQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLrVLNLLEMPRSGTLNIagNHFDFSKTPSDKaIRELRR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 343 HIGYVSPEM----HRAYLKNLPAIEIVASGLHDS------IGLYKRPQPEQMAvcewwmdifgiaglkDKPFLQLSSGEQ 412
Cdd:PRK11124 83 NVGMVFQQYnlwpHLTVQQNLIEAPCRVLGLSKDqalaraEKLLERLRLKPYA---------------DRFPLHLSGGQQ 147
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 413 RLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK11124 148 QRVAIARALMMEPQVLLFDEPTAALDPEITAQIVSIIREL-AETGITQVIVTH 199
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
35-478 |
1.40e-06 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 50.77 E-value: 1.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 35 AIVGPNGGGKSLFVDTLTGKYPLREGTLQY-----DFF-PSATQ-----------------TVYDNVkYIA--FRDTYGA 89
Cdd:PRK10762 34 ALVGENGAGKSTMMKVLTGIYTRDAGSILYlgkevTFNgPKSSQeagigiihqelnlipqlTIAENI-FLGreFVNRFGR 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 90 ADANYYYQQ------RWN-AHDQdetpdvREMLGEikdeqlknelfelfrieplldkkiilLSSGELRKFQLTKTLLTAP 162
Cdd:PRK10762 113 IDWKKMYAEadkllaRLNlRFSS------DKLVGE--------------------------LSIGEQQMVEIAKVLSFES 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 163 RVLIMDNPFIGLDAPTRELLFSLLERLtKMSSVQIIlvlsmlddipsFITHVIPvdkmEVFPKVEReayLDAFRD----- 237
Cdd:PRK10762 161 KVIIMDEPTDALTDTETESLFRVIREL-KSQGRGIV-----------YISHRLK----EIFEICDD---VTVFRDgqfia 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 238 -RDIAvSFDElqKRIIDLPYdGNNYDsDEVVKLNKV--SIRYDDRTI----LNELDWTVRRGEKWALSGENGAGKSTLLS 310
Cdd:PRK10762 222 eREVA-DLTE--DSLIEMMV-GRKLE-DQYPRLDKApgEVRLKVDNLsgpgVNDVSFTLRKGEILGVSGLMGAGRTELMK 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 311 LVCADNPQSyACDISLFGRKRGTGESIWEIKKHIGYVSPEMHRAYL-------KNLpaiEIVASGLHDSIGLYKRPQPEQ 383
Cdd:PRK10762 297 VLYGALPRT-SGYVTLDGHEVVTRSPQDGLANGIVYISEDRKRDGLvlgmsvkENM---SLTALRYFSRAGGSLKHADEQ 372
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 384 MAVCEWwMDIFGI-AGLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIM 462
Cdd:PRK10762 373 QAVSDF-IRLFNIkTPSMEQAIGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQF-KAEGLSIIL 450
|
490
....*....|....*...
gi 2469828120 463 VThyeSELPDTI--TNRI 478
Cdd:PRK10762 451 VS---SEMPEVLgmSDRI 465
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
19-175 |
1.43e-06 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 49.51 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDffpsatqtvYDNVKYIAFRDT------YGAADA 92
Cdd:PRK10895 17 RVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIID---------DEDISLLPLHARarrgigYLPQEA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 93 NYYyqQRWNAHDQ-DETPDVREMLGEIKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPF 171
Cdd:PRK10895 88 SIF--RRLSVYDNlMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLDEPF 165
|
....
gi 2469828120 172 IGLD 175
Cdd:PRK10895 166 AGVD 169
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
282-465 |
1.47e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 49.83 E-value: 1.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTLLSLVCAD-NPQSYACDISLFGRKRGTG-ESIWEIKKHIGYVS--PEmhrAYLK 357
Cdd:PRK13641 23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALlKPSSGTITIAGYHITPETGnKNLKKLRKKVSLVFqfPE---AQLF 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 358 NLPAIEIVASGLHDsIGLYKRPQPEQMAVcewWMDIFGIA-GLKDKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHG 436
Cdd:PRK13641 100 ENTVLKDVEFGPKN-FGFSEDEAKEKALK---WLKKVGLSeDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAG 175
|
170 180
....*....|....*....|....*....
gi 2469828120 437 LDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK13641 176 LDPEGRKEMMQLFKDY-QKAGHTVILVTH 203
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
399-485 |
1.57e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 49.70 E-value: 1.57e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 399 LKDKPFlQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNrrrVKKVIEAFCK--RKDKTMIMVTHyesELPDTI-- 474
Cdd:PRK13651 159 LQRSPF-ELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQG---VKEILEIFDNlnKQGKTIILVTH---DLDNVLew 231
|
90
....*....|..
gi 2469828120 475 TNR-IFLKRNQV 485
Cdd:PRK13651 232 TKRtIFFKDGKI 243
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
19-213 |
2.44e-06 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 48.41 E-value: 2.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYdffpsatqtvydNVKYIAFRDTYGAAdanYYYQQ 98
Cdd:cd03226 14 EILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILL------------NGKPIKAKERRKSI---GYVMQ 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 99 rwNAHDQDETPDVREMLGEIKDE-----QLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIG 173
Cdd:cd03226 79 --DVDYQLFTDSVREELLLGLKEldagnEQAETVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTSG 156
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 174 LDAPTRELLFSLLERLTKMSSVQIIlvlsmlddipsfITH 213
Cdd:cd03226 157 LDYKNMERVGELIRELAAQGKAVIV------------ITH 184
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
126-207 |
2.75e-06 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 48.95 E-value: 2.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 126 ELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK------MSSVQIIL 199
Cdd:COG4152 112 EWLERLGLGDRANKKVEELSKGNQQKVQLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAkgttviFSSHQMEL 191
|
....*...
gi 2469828120 200 VLSMLDDI 207
Cdd:COG4152 192 VEELCDRI 199
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
247-465 |
3.38e-06 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 50.03 E-value: 3.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 247 LQKRIIDLPYDG-----NNYDSDEVVKLNKVSIRYDDRT---ILNELDWTVRRGEKWALSGENGAGKSTLLSL------- 311
Cdd:PTZ00265 1141 IRKSNIDVRDNGgirikNKNDIKGKIEIMDVNFRYISRPnvpIYKDLTFSCDSKKTTAIVGETGSGKSTVMSLlmrfydl 1220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 312 -----VCADNPQSYacDISLFGRKRGTGESIWEIKKHIGYVSPEM-----HRAYLKN-----LPAIEIVASGLHDSIGLY 376
Cdd:PTZ00265 1221 kndhhIVFKNEHTN--DMTNEQDYQGDEEQNVGMKNVNEFSLTKEggsgeDSTVFKNsgkilLDGVDICDYNLKDLRNLF 1298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 377 KRPQPEQM-----------------------AVCEWW-MDIFgIAGLKDK------PFLQ-LSSGEQRLALLARAFVKDP 425
Cdd:PTZ00265 1299 SIVSQEPMlfnmsiyenikfgkedatredvkRACKFAaIDEF-IESLPNKydtnvgPYGKsLSGGQKQRIAIARALLREP 1377
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2469828120 426 ELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PTZ00265 1378 KILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH 1417
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
22-200 |
4.26e-06 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 47.63 E-value: 4.26e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTL----------------------QYDFFPSatQTVYDNvk 79
Cdd:cd03301 17 DDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIyiggrdvtdlppkdrdiamvfqNYALYPH--MTVYDN-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 80 yIAFRDTygaadanyyyqqrwnahdqdetpdVREMLGEIKDEQLKnELFELFRIEPLLDKKIILLSSGELRKFQLTKTLL 159
Cdd:cd03301 93 -IAFGLK------------------------LRKVPKDEIDERVR-EVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIV 146
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2469828120 160 TAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV 200
Cdd:cd03301 147 REPKVFLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYV 187
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
19-190 |
4.66e-06 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 47.91 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAkPVTATIGADEHIAIVGPNGGGKS----------------LFVDTLTGKYPLREGTLQYDFF-----PSATQTVYdn 77
Cdd:COG4138 11 RLG-PISAQVNAGELIHLIGPNGAGKStllarmagllpgqgeiLLNGRPLSDWSAAELARHRAYLsqqqsPPFAMPVF-- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 78 vKYIAFrdtygaadanyyyqqrwnaHDQDETPDVremlgeiKDEQLKNELFELFRIEPLLDKKIILLSSGELRKFQLTKT 157
Cdd:COG4138 88 -QYLAL-------------------HQPAGASSE-------AVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAV 140
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 2469828120 158 LLT-------APRVLIMDNPFIGLDAPTRELLFSLLERLT 190
Cdd:COG4138 141 LLQvwptinpEGQLLLLDEPMNSLDVAQQAALDRLLRELC 180
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
266-480 |
6.41e-06 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 47.76 E-value: 6.41e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRT-ILNELDWTVRRGEKWALSGENGAGKSTLL------------SLVCADNPQSYacdislfgrkrg 332
Cdd:PRK13639 1 ILETRDLKYSYPDGTeALKGINFKAEKGEMVALLGPNGAGKSTLFlhfngilkptsgEVLIKGEPIKY------------ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 333 TGESIWEIKKHIGYVspemhrayLKNlPAIEIVASGLHDSIGL----YKRPQPEQMAVCEWWMDIFGIAGLKDKPFLQLS 408
Cdd:PRK13639 69 DKKSLLEVRKTVGIV--------FQN-PDDQLFAPTVEEDVAFgplnLGLSKEEVEKRVKEALKAVGMEGFENKPPHHLS 139
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2469828120 409 SGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTHyESELPDTITNRIFL 480
Cdd:PRK13639 140 GGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQIMKLLYDL-NKEGITIIISTH-DVDLVPVYADKVYV 209
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
22-207 |
7.13e-06 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 46.27 E-value: 7.13e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPsatqtvydnvkyIAFRDTYGAADANYYYqqrwn 101
Cdd:cd03215 17 RDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKP------------VTRRSPRDAIRAGIAY----- 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 102 ahdqdeTPDVREMLGeikdeqlknelfeLFRIEPLLDKKII--LLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTR 179
Cdd:cd03215 80 ------VPEDRKREG-------------LVLDLSVAENIALssLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVGAK 140
|
170 180
....*....|....*....|....*...
gi 2469828120 180 ELLFSLLERLTKmSSVQIILVLSMLDDI 207
Cdd:cd03215 141 AEIYRLIRELAD-AGKAVLLISSELDEL 167
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
33-219 |
7.20e-06 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 47.81 E-value: 7.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 33 HIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIafRDTYGAAdANYYYQQRWNAHDQDETPDVR 112
Cdd:PRK13643 34 YTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVGDIVVSSTSKQKEIKPV--RKKVGVV-FQFPESQLFEETVLKDVAFGP 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 113 EMLGEIKDE--QLKNELFELFRI-EPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERL 189
Cdd:PRK13643 111 QNFGIPKEKaeKIAAEKLEMVGLaDEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGLDPKARIEMMQLFESI 190
|
170 180 190
....*....|....*....|....*....|
gi 2469828120 190 TKMSSVqIILVLSMLDDIPSFITHVIPVDK 219
Cdd:PRK13643 191 HQSGQT-VVLVTHLMDDVADYADYVYLLEK 219
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
267-465 |
9.40e-06 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 46.64 E-value: 9.40e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLslvcadnpqsyacdISLFGRKRGTGESIWEIKKHI 344
Cdd:cd03369 7 IEVENLSVRYapDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLI--------------LALFRFLEAEEGKIEIDGIDI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMHRAYLKNLPAIEIVASGlhdSIGLYKRPQPEQMAVcewwmDIFGIAGLKDKPfLQLSSGEQRLALLARAFVKD 424
Cdd:cd03369 73 STIPLEDLRSSLTIIPQDPTLFSG---TIRSNLDPFDEYSDE-----EIYGALRVSEGG-LNLSQGQRQLLCLARALLKR 143
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 2469828120 425 PELLILDEPLHGLDTYNRRRVKKVI-EAFckrKDKTMIMVTH 465
Cdd:cd03369 144 PRVLVLDEATASIDYATDALIQKTIrEEF---TNSTILTIAH 182
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
272-439 |
1.04e-05 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 48.18 E-value: 1.04e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 272 VSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSY--ACDISLFGRKRGTgesiwEIKKHIGYVsp 349
Cdd:TIGR00956 769 VKIKKEKRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTGVitGGDRLVNGRPLDS-----SFQRSIGYV-- 841
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 350 EMHRAYLKNLpaieIVASGLHDSIGLyKRPQP----EQMAVCEWWMDIFGIAGLKDKPFLQLSSG---EQRLAL-LARAF 421
Cdd:TIGR00956 842 QQQDLHLPTS----TVRESLRFSAYL-RQPKSvsksEKMEYVEEVIKLLEMESYADAVVGVPGEGlnvEQRKRLtIGVEL 916
|
170
....*....|....*....
gi 2469828120 422 VKDPELLI-LDEPLHGLDT 439
Cdd:TIGR00956 917 VAKPKLLLfLDEPTSGLDS 935
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
278-438 |
1.08e-05 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 47.78 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 278 DRTILNELDWTVRRGEKWALSGENGAGKS-TLLSL--VCADNPQSY-ACDISLFG---------RKRGT-GESIWEIkkh 343
Cdd:PRK15134 21 VRTVVNDVSLQIEAGETLALVGESGSGKSvTALSIlrLLPSPPVVYpSGDIRFHGesllhaseqTLRGVrGNKIAMI--- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 344 igYVSPEMHRAYLKNLPA--IEIVAsgLHDsiGLYKRPQPEQMAVCewwMDIFGI---AG-LKDKPFlQLSSGEQRLALL 417
Cdd:PRK15134 98 --FQEPMVSLNPLHTLEKqlYEVLS--LHR--GMRREAARGEILNC---LDRVGIrqaAKrLTDYPH-QLSGGERQRVMI 167
|
170 180
....*....|....*....|.
gi 2469828120 418 ARAFVKDPELLILDEPLHGLD 438
Cdd:PRK15134 168 AMALLTRPELLIADEPTTALD 188
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
407-483 |
1.24e-05 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 47.80 E-value: 1.24e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 407 LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKrKDKTMIMVThyeSELPDT--ITNRIFLKRN 483
Cdd:PRK10982 392 LSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAK-KDKGIIIIS---SEMPELlgITDRILVMSN 466
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
22-223 |
1.59e-05 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 45.11 E-value: 1.59e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGtlqydffpsatqTVYDNVKYIAFRDTYGAADANYY--YQqr 99
Cdd:cd03216 17 DGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSG------------EILVDGKEVSFASPRDARRAGIAmvYQ-- 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 100 wnahdqdetpdvremlgeikdeqlknelfelfrieplldkkiilLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTR 179
Cdd:cd03216 83 --------------------------------------------LSVGERQMVEIARALARNARLLILDEPTAALTPAEV 118
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 180 ELLFSLLERLTKmSSVQIIlvlsmlddipsFITHvipvdKM-EVF 223
Cdd:cd03216 119 ERLFKVIRRLRA-QGVAVI-----------FISH-----RLdEVF 146
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
127-200 |
1.95e-05 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 46.34 E-value: 1.95e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 127 LFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLtkMSSVQIILV 200
Cdd:PRK13537 122 LLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDVLVLDEPTTGLDPQARHLMWERLRSL--LARGKTILL 193
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
288-465 |
2.07e-05 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 46.21 E-value: 2.07e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 288 TVRRGEKWALSGENGAGKSTLLSLVCA---------DNPQSYACDISLFgrkRGTGESIWEIKKHIGYVSPEMHRAYLKN 358
Cdd:cd03236 22 VPREGQVLGLVGPNGIGKSTALKILAGklkpnlgkfDDPPDWDEILDEF---RGSELQNYFTKLLEGDVKVIVKPQYVDL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 LPAieiVASGlhDSIGLYKRPqpEQMAVCEWWMDIFGIAGLKDKPFLQLSSGE-QRLALLARAfVKDPELLILDEPLHGL 437
Cdd:cd03236 99 IPK---AVKG--KVGELLKKK--DERGKLDELVDQLELRHVLDRNIDQLSGGElQRVAIAAAL-ARDADFYFFDEPSSYL 170
|
170 180
....*....|....*....|....*...
gi 2469828120 438 DTYNRRRVKKVIEAFCKrKDKTMIMVTH 465
Cdd:cd03236 171 DIKQRLNAARLIRELAE-DDNYVLVVEH 197
|
|
| OpuBA |
COG1125 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
268-465 |
2.30e-05 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440742 [Multi-domain] Cd Length: 306 Bit Score: 46.24 E-value: 2.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDDRTI-LNELDWTVRRGEKWALSGENGAGKSTLLSLVcadN----PQSyacdislfGRKRGTGESIWEIK- 341
Cdd:COG1125 3 EFENVTKRYPDGTVaVDDLSLTIPAGEFTVLVGPSGCGKTTTLRMI---NrliePTS--------GRILIDGEDIRDLDp 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 342 ----KHIGYVS------PemHRAYLKNlpaIEIVAsglhdsiGLYKRPQPEQMAVCEWWMDIFGI--AGLKDK-PFlQLS 408
Cdd:COG1125 72 velrRRIGYVIqqiglfP--HMTVAEN---IATVP-------RLLGWDKERIRARVDELLELVGLdpEEYRDRyPH-ELS 138
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2469828120 409 SGE-QRLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG1125 139 GGQqQRVGV-ARALAADPPILLMDEPFGALDPITREQLQDELLRLQRELGKTIVFVTH 195
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
399-465 |
2.50e-05 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 45.93 E-value: 2.50e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 399 LKDK---PFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:PRK14243 141 VKDKlkqSGLSLSGGQQQRLCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL--KEQYTIIIVTH 208
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
275-438 |
2.64e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 47.04 E-value: 2.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 275 RYDDRTILNELDWTVRRGEKWALSGENGAGKST-------LLslvcadnPQSyACDISLFGRKRGTGESiwEIKKHIGYV 347
Cdd:NF033858 275 RFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTtmkmltgLL-------PAS-EGEAWLFGQPVDAGDI--ATRRRVGYM 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SP--------------EMHrAYLKNLPAIEIvasglhdsiglykRPQPEQMavcewwMDIFGIAGLKDKPFLQLSSG-EQ 412
Cdd:NF033858 345 SQafslygeltvrqnlELH-ARLFHLPAAEI-------------AARVAEM------LERFDLADVADALPDSLPLGiRQ 404
|
170 180
....*....|....*....|....*.
gi 2469828120 413 RLALlARAFVKDPELLILDEPLHGLD 438
Cdd:NF033858 405 RLSL-AVAVIHKPELLILDEPTSGVD 429
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
24-271 |
2.95e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 45.93 E-value: 2.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIafRDTYGAAdanYYYQQRWNAH 103
Cdd:PRK13646 26 VNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPV--RKRIGMV---FQFPESQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 104 DQDEtpdvREMLGEIKD-----EQLKNELFELFrIE-----PLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIG 173
Cdd:PRK13646 101 DTVE----REIIFGPKNfkmnlDEVKNYAHRLL-MDlgfsrDVMSQSPFQMSGGQMRKIAIVSILAMNPDIIVLDEPTAG 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 174 LDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFITHVIPVDKMEVfpkVEREAYLDAFRDRdiavsfDELQKRIID 253
Cdd:PRK13646 176 LDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSI---VSQTSPKELFKDK------KKLADWHIG 246
|
250
....*....|....*...
gi 2469828120 254 LPydgnnydsdEVVKLNK 271
Cdd:PRK13646 247 LP---------EIVQLQY 255
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
266-444 |
3.14e-05 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 46.66 E-value: 3.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 266 VVKLNKVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVC-ADNPQSyacdislfGRKRGTGESIWEiKKHI 344
Cdd:NF033858 1 VARLEGVSHRYGKTVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAgARKIQQ--------GRVEVLGGDMAD-ARHR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 345 GYVSPEMhrAYL-----KNLPAIEIVASGLhDSIG-LYKRPQPEqmavCEWWMDIF----GIAGLKDKPFLQLSSG-EQR 413
Cdd:NF033858 72 RAVCPRI--AYMpqglgKNLYPTLSVFENL-DFFGrLFGQDAAE----RRRRIDELlratGLAPFADRPAGKLSGGmKQK 144
|
170 180 190
....*....|....*....|....*....|.
gi 2469828120 414 LALLArAFVKDPELLILDEPLHGLDTYNRRR 444
Cdd:NF033858 145 LGLCC-ALIHDPDLLILDEPTTGVDPLSRRQ 174
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
296-465 |
4.19e-05 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 45.64 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 296 ALSGENGAGKSTLLSLVCA-DNPQSyaCDISLFGR---KRGTGESIWEIKKHIGYVSPEM----HRAYLKNLpaieivas 367
Cdd:PRK11144 28 AIFGRSGAGKTSLINAISGlTRPQK--GRIVLNGRvlfDAEKGICLPPEKRRIGYVFQDArlfpHYKVRGNL-------- 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 368 glhdsigLY--KRPQPEQMAvcewwmDI---FGIAGLKDKPFLQLSSGE-QRLALlARAFVKDPELLILDEPLHGLDTYN 441
Cdd:PRK11144 98 -------RYgmAKSMVAQFD------KIvalLGIEPLLDRYPGSLSGGEkQRVAI-GRALLTAPELLLMDEPLASLDLPR 163
|
170 180
....*....|....*....|....
gi 2469828120 442 RRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK11144 164 KRELLPYLERLAREINIPILYVSH 187
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
24-168 |
4.30e-05 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 44.83 E-value: 4.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGT------------LQYDFFPSAtqTVYDNVKYIAfrdtygaad 91
Cdd:cd03220 41 VSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTvtvrgrvssllgLGGGFNPEL--TGRENIYLNG--------- 109
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 92 anyyyqqRWNAHDQDEtpdVREMLGEIKdeqlknELFELfriEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMD 168
Cdd:cd03220 110 -------RLLGLSRKE---IDEKIDEII------EFSEL---GDFIDLPVKTYSSGMKARLAFAIATALEPDILLID 167
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
296-484 |
4.81e-05 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 44.52 E-value: 4.81e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 296 ALSGENGAGKSTLLSlvcadnpqsyACDISLFGRKRGTGESiweikkhiGYVSPEMHRAYlKNLPAIEIVASglHDSIGL 375
Cdd:cd03240 26 LIVGQNGAGKTTIIE----------ALKYALTGELPPNSKG--------GAHDPKLIREG-EVRAQVKLAFE--NANGKK 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 376 YKrpqpeqmavCEWWMDIFGIA-----GLKDKPFLQ----LSSGEQ-------RLALlARAFVKDPELLILDEPLHGLDT 439
Cdd:cd03240 85 YT---------ITRSLAILENVifchqGESNWPLLDmrgrCSGGEKvlasliiRLAL-AETFGSNCGILALDEPTTNLDE 154
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 2469828120 440 YNRRRV-KKVIEAFCKRKDKTMIMVTHYEsELPDTITNRIFLKRNQ 484
Cdd:cd03240 155 ENIEESlAEIIEERKSQKNFQLIVITHDE-ELVDAADHIYRVEKDG 199
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
131-438 |
5.10e-05 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 45.79 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 131 FRIEPllDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK--MSsvqIIlvlsmlddip 208
Cdd:COG3845 131 LDVDP--DAKVEDLSVGEQQRVEILKALYRGARILILDEPTAVLTPQEADELFEILRRLAAegKS---II---------- 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 209 sFITHvipvdKM-EVFpkvereayldAFRDRdIAV---------------SFDELQK----RIIDLPYDGNNYDSDEVV- 267
Cdd:COG3845 196 -FITH-----KLrEVM----------AIADR-VTVlrrgkvvgtvdtaetSEEELAElmvgREVLLRVEKAPAEPGEVVl 258
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 268 KLNKVSIRYDD-RTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSyACDISLFGRKRgTGESIWEIKKH-IG 345
Cdd:COG3845 259 EVENLSVRDDRgVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPA-SGSIRLDGEDI-TGLSPRERRRLgVA 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVsPE--MHRAYLKNLPAIEIVASGLHDSIGLYKRP--QPEQM-AVCEWWMDIFGI-AGLKDKPFLQLSSGEQRLALLAR 419
Cdd:COG3845 337 YI-PEdrLGRGLVPDMSVAENLILGRYRRPPFSRGGflDRKAIrAFAEELIEEFDVrTPGPDTPARSLSGGNQQKVILAR 415
|
330
....*....|....*....
gi 2469828120 420 AFVKDPELLILDEPLHGLD 438
Cdd:COG3845 416 ELSRDPKLLIAAQPTRGLD 434
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
19-207 |
5.70e-05 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 45.61 E-value: 5.70e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 19 RLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLReGTLQydffpsatqtvydnVKYIAFRDtygaADANYYYQQ 98
Cdd:PRK11174 364 TLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLGFLPYQ-GSLK--------------INGIELRE----LDPESWRKH 424
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 99 -RW---NAHDQDETpdVRE--MLG--EIKDEQLKNEL-----FELFRIEPL-LDKKI----ILLSSGELRKFQLTKTLLT 160
Cdd:PRK11174 425 lSWvgqNPQLPHGT--LRDnvLLGnpDASDEQLQQALenawvSEFLPLLPQgLDTPIgdqaAGLSVGQAQRLALARALLQ 502
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2469828120 161 APRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVqiILVLSMLDDI 207
Cdd:PRK11174 503 PCQLLLLDEPTASLDAHSEQLVMQALNAASRRQTT--LMVTHQLEDL 547
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
20-187 |
6.90e-05 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 45.27 E-value: 6.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 20 LAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYdffpsatqTVYDNVKYIAfRDTYG--AADANYY-Y 96
Cdd:PRK15064 334 LFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGELEPDSGTVKW--------SENANIGYYA-QDHAYdfENDLTLFdW 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 97 QQRWNAHDQDETPdVREMLGEIkdeqlknelfeLFRIEPlLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDA 176
Cdd:PRK15064 405 MSQWRQEGDDEQA-VRGTLGRL-----------LFSQDD-IKKSVKVLSGGEKGRMLFGKLMMQKPNVLVMDEPTNHMDM 471
|
170
....*....|.
gi 2469828120 177 PTRELLFSLLE 187
Cdd:PRK15064 472 ESIESLNMALE 482
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
267-465 |
7.20e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 44.74 E-value: 7.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRYDDRT-----ILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAcdISLFGRKRGTGES----I 337
Cdd:PRK13649 3 INLQNVSYTYQAGTpfegrALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQG--SVRVDDTLITSTSknkdI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 338 WEIKKHIGYVS--PEmhrAYLKNLPAIEIVASGLHDsiglYKRPQPEQMAVCEWWMDIFGIA-GLKDKPFLQLSSGEQRL 414
Cdd:PRK13649 81 KQIRKKVGLVFqfPE---SQLFEETVLKDVAFGPQN----FGVSQEEAEALAREKLALVGISeSLFEKNPFELSGGQMRR 153
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2469828120 415 ALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFcKRKDKTMIMVTH 465
Cdd:PRK13649 154 VAIAGILAMEPKILVLDEPTAGLDPKGRKELMTLFKKL-HQSGMTIVLVTH 203
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
115-225 |
7.95e-05 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 44.61 E-value: 7.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 115 LGEIKDEQLKN--ELFELFRI-EPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK 191
Cdd:PRK13645 119 LGENKQEAYKKvpELLKLVQLpEDYVKRSPFELSGGQKRRVALAGIIAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNK 198
|
90 100 110
....*....|....*....|....*....|....
gi 2469828120 192 MSSVQIILVLSMLDDIPSFITHVIPVDKMEVFPK 225
Cdd:PRK13645 199 EYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISI 232
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
125-189 |
9.38e-05 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 43.87 E-value: 9.38e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 125 NELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERL 189
Cdd:cd03296 118 HELLKLVQLDWLADRYPAQLSGGQRQRVALARALAVEPKVLLLDEPFGALDAKVRKELRRWLRRL 182
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
277-329 |
9.45e-05 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 44.05 E-value: 9.45e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAC-------DISLFGR 329
Cdd:PRK13547 12 RHRAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLTGGGAPrgarvtgDVTLNGE 71
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
406-484 |
9.53e-05 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 45.41 E-value: 9.53e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2469828120 406 QLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTHYESELpdTITNRIFLKRNQ 484
Cdd:PTZ00265 579 KLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITIIIAHRLSTI--RYANTIFVLSNR 655
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
397-465 |
1.13e-04 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 43.87 E-value: 1.13e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 397 AGL----KDK---PFLQLSSGEQ-RLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTH 465
Cdd:COG1117 138 AALwdevKDRlkkSALGLSGGQQqRLCI-ARALAVEPEVLLMDEPTSALDPISTAKIEELILEL--KKDYTIVIVTH 211
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
27-191 |
1.22e-04 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 44.82 E-value: 1.22e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 27 TIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAT--------------Q-------TVYDNVkyiafrd 85
Cdd:COG2274 497 TIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQidpaslrrqigvvlQdvflfsgTIRENI------- 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 86 TYGAADANyyYQQRWNA------HDqdetpDVREMlgeikdeqlknelfelfriePL-LDKKI----ILLSSGELRKFQL 154
Cdd:COG2274 570 TLGDPDAT--DEEIIEAarlaglHD-----FIEAL--------------------PMgYDTVVgeggSNLSGGQRQRLAI 622
|
170 180 190
....*....|....*....|....*....|....*..
gi 2469828120 155 TKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTK 191
Cdd:COG2274 623 ARALLRNPRILILDEATSALDAETEAIILENLRRLLK 659
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
282-438 |
1.76e-04 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 43.90 E-value: 1.76e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 282 LNELDWTVRRGEKWALSGENGAGKSTL----LSLVcadnpqSYACDISLFGRK--RGTGESIWEIKKHIGYV-------- 347
Cdd:COG4172 302 VDGVSLTLRRGETLGLVGESGSGKSTLglalLRLI------PSEGEIRFDGQDldGLSRRALRPLRRRMQVVfqdpfgsl 375
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 348 SPEMhraylknlPAIEIVASGLH-DSIGLyKRPQPEQMAVcewwmDIFGIAGLkDKPFLQ-----LSSGE-QRLALlARA 420
Cdd:COG4172 376 SPRM--------TVGQIIAEGLRvHGPGL-SAAERRARVA-----EALEEVGL-DPAARHrypheFSGGQrQRIAI-ARA 439
|
170
....*....|....*...
gi 2469828120 421 FVKDPELLILDEPLHGLD 438
Cdd:COG4172 440 LILEPKLLVLDEPTSALD 457
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
267-485 |
3.18e-04 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 43.17 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 267 VKLNKVSIRY-DDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLVCADNPQSYAcDISLFGRKRGTgESIWEIKKHIG 345
Cdd:PRK10790 341 IDIDNVSFAYrDDNLVLQNINLSVPSRGFVALVGHTGSGKSTLASLLMGYYPLTEG-EIRLDGRPLSS-LSHSVLRQGVA 418
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 346 YVSPE---MHRAYLKNLP------------AIEIV---------ASGLHDSIGlykrpqpEQMAvcewwmdifgiaglkd 401
Cdd:PRK10790 419 MVQQDpvvLADTFLANVTlgrdiseeqvwqALETVqlaelarslPDGLYTPLG-------EQGN---------------- 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 402 kpflQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFckRKDKTMIMVTHYESEL--PDTItnrIF 479
Cdd:PRK10790 476 ----NLSVGQKQLLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAV--REHTTLVVIAHRLSTIveADTI---LV 546
|
....*.
gi 2469828120 480 LKRNQV 485
Cdd:PRK10790 547 LHRGQA 552
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
269-465 |
3.18e-04 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 43.04 E-value: 3.18e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 269 LNKVSIRYDDRTI-LNELDWTVRRGEKWALSGENGAGKSTLLSLVCADN-PQSyaCDISLFGRKRgTGESIWEIKKHIGY 346
Cdd:PRK10522 325 LRNVTFAYQDNGFsVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYqPQS--GEILLDGKPV-TAEQPEDYRKLFSA 401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 347 VSPEMHraylknlpaieivasgLHDSIgLYKRPQPEQMAVCEWWMDIFGIAG---LKDKPF--LQLSSGE-QRLALLArA 420
Cdd:PRK10522 402 VFTDFH----------------LFDQL-LGPEGKPANPALVEKWLERLKMAHkleLEDGRIsnLKLSKGQkKRLALLL-A 463
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 421 FVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:PRK10522 464 LAEERDILLLDEWAADQDPHFRREFYQVLLPLLQEMGKTIFAISH 508
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
2-201 |
3.88e-04 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 42.08 E-value: 3.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 2 SQNTFSMAGGVARNPLVRLAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDffpsatQTVYDNVKYI 81
Cdd:PRK10575 8 SDTTFALRNVSFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLD------AQPLESWSSK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 82 AFrdtygAADANYYYQQRWNAhdqdETPDVREM-----------LGE--IKDEQLKNELFELFRIEPLLDKKIILLSSGE 148
Cdd:PRK10575 82 AF-----ARKVAYLPQQLPAA----EGMTVRELvaigrypwhgaLGRfgAADREKVEEAISLVGLKPLAHRLVDSLSGGE 152
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 149 LRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVL 201
Cdd:PRK10575 153 RQRAWIAMLVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVL 205
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
144-208 |
5.14e-04 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 42.35 E-value: 5.14e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 144 LSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKmSSVQIILVLSMLDDIP 208
Cdd:PRK15439 404 LSGGNQQKVLIAKCLEASPQLLIVDEPTRGVDVSARNDIYQLIRSIAA-QNVAVLFISSDLEEIE 467
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
271-451 |
5.58e-04 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 41.07 E-value: 5.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 271 KVSIRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLslvcadnpqsyacDIsLFGRkrgtgesiweikKHIGYVSPE 350
Cdd:cd03232 12 TVPVKGGKRQLLNNISGYVKPGTLTALMGESGAGKTTLL-------------DV-LAGR------------KTAGVITGE 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 351 MHRAYLKNLPAIEIvasglhdSIGlYKrpqpEQmavcewwMDIFgIAGLKDKPFLQLS------SGEQRLAL-LARAFVK 423
Cdd:cd03232 66 ILINGRPLDKNFQR-------STG-YV----EQ-------QDVH-SPNLTVREALRFSallrglSVEQRKRLtIGVELAA 125
|
170 180 190
....*....|....*....|....*....|..
gi 2469828120 424 DPELLILDEPLHGLDT---YN-RRRVKKVIEA 451
Cdd:cd03232 126 KPSILFLDEPTSGLDSqaaYNiVRFLKKLADS 157
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
291-485 |
5.83e-04 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 40.43 E-value: 5.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 291 RGEKWALSGENGAGKSTLLSLVCAdnpqsyacdisLFGRKrgtgesiweiKKHIGYVSPEMHRAYLKNLPAIEIVASGLH 370
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALAR-----------ELGPP----------GGGVIYIDGEDILEEVLDQLLLIIVGGKKA 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 371 DSiglykrpqpeqmavcewwmdifgiaglkdkpflqlsSGEQRLA-LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI 449
Cdd:smart00382 60 SG------------------------------------SGELRLRlALALARKLKPDVLILDEITSLLDAEQEALLLLLE 103
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 2469828120 450 EA-----FCKRKDKTMIMVTHYESELPDTITNRIFLKRNQV 485
Cdd:smart00382 104 ELrllllLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVL 144
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
22-207 |
5.93e-04 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 41.45 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTL----------------------QYDFFPSATqtVYDNvk 79
Cdd:cd03300 17 DGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEIlldgkditnlpphkrpvntvfqNYALFPHLT--VFEN-- 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 80 yIAFRDTYGAADANyyyqqrwnahdqdetpdvremlgEIKDEQlkNELFELFRIEPLLDKKIILLSSGELRKFQLTKTLL 159
Cdd:cd03300 93 -IAFGLRLKKLPKA-----------------------EIKERV--AEALDLVQLEGYANRKPSQLSGGQQQRVAIARALV 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 2469828120 160 TAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV-------LSMLDDI 207
Cdd:cd03300 147 NEPKVLLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVthdqeeaLTMSDRI 201
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
22-207 |
6.35e-04 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 41.54 E-value: 6.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSATQTVYDNVKYIAFrdtygaadanyYYQ---- 97
Cdd:PRK13635 24 KDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGMVLSEETVWDVRRQVGM-----------VFQnpdn 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 98 QRWNAHDQDETPDVREMLGEIKDEQLK--NELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLD 175
Cdd:PRK13635 93 QFVGATVQDDVAFGLENIGVPREEMVErvDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLD 172
|
170 180 190
....*....|....*....|....*....|..
gi 2469828120 176 APTREllfSLLERLTKMSSVQIILVLSMLDDI 207
Cdd:PRK13635 173 PRGRR---EVLETVRQLKEQKGITVLSITHDL 201
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
133-222 |
8.37e-04 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 41.37 E-value: 8.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 133 IEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDIPSFIT 212
Cdd:PRK13636 131 IEHLKDKPTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCD 210
|
90
....*....|
gi 2469828120 213 HVIPVDKMEV 222
Cdd:PRK13636 211 NVFVMKEGRV 220
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
125-187 |
9.14e-04 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 40.70 E-value: 9.14e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 125 NELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLE 187
Cdd:PRK13540 109 TELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTIITKIQ 171
|
|
| PvdE |
COG4615 |
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ... |
23-65 |
1.25e-03 |
|
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];
Pssm-ID: 443659 [Multi-domain] Cd Length: 547 Bit Score: 41.32 E-value: 1.25e-03
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 2469828120 23 PVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD 65
Cdd:COG4615 350 PIDLTIRRGELVFIVGGNGSGKSTLAKLLTGLYRPESGEILLD 392
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
134-219 |
1.45e-03 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 40.58 E-value: 1.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 134 EPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVqIILVLSMLDDIPSFITH 213
Cdd:PRK13641 136 EDLISKSPFELSGGQMRRVAIAGVMAYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQKAGHT-VILVTHNMDDVAEYADD 214
|
....*.
gi 2469828120 214 VIPVDK 219
Cdd:PRK13641 215 VLVLEH 220
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
251-465 |
1.49e-03 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 41.43 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 251 IIDLPYDGNNYDSDEVVKLNKVSIRY--DDRTILNELDWTVRRGEKWALSGENGAGKSTLLS----LVCADNpqsyacDI 324
Cdd:TIGR01271 1202 VIENPHAQKCWPSGGQMDVQGLTAKYteAGRAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSallrLLSTEG------EI 1275
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 325 SLFGRKRGTgESIWEIKKHIGyVSPE----MHRAYLKNLPAIEIVAS----GLHDSIGLykrpqpeqMAVCEWWMDIFGI 396
Cdd:TIGR01271 1276 QIDGVSWNS-VTLQTWRKAFG-VIPQkvfiFSGTFRKNLDPYEQWSDeeiwKVAEEVGL--------KSVIEQFPDKLDF 1345
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 397 AgLKDKPFLqLSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI-EAFckrKDKTMIMVTH 465
Cdd:TIGR01271 1346 V-LVDGGYV-LSNGHKQLMCLARSILSKAKILLLDEPSAHLDPVTLQIIRKTLkQSF---SNCTVILSEH 1410
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
20-64 |
1.91e-03 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 39.06 E-value: 1.91e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 2469828120 20 LAKPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQY 64
Cdd:cd03223 16 LLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIGM 60
|
|
| AAA_21 |
pfam13304 |
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being ... |
403-465 |
2.00e-03 |
|
AAA domain, putative AbiEii toxin, Type IV TA system; Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.
Pssm-ID: 433102 [Multi-domain] Cd Length: 303 Bit Score: 40.07 E-value: 2.00e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2469828120 403 PFLQLSSGEQRLALLA---RAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAfCKRKDKTMIMVTH 465
Cdd:pfam13304 233 PAFELSDGTKRLLALLaalLSALPKGGLLLIDEPESGLHPKLLRRLLELLKE-LSRNGAQLILTTH 297
|
|
| RepA |
COG3598 |
RecA-family ATPase [Replication, recombination and repair]; |
284-465 |
2.02e-03 |
|
RecA-family ATPase [Replication, recombination and repair];
Pssm-ID: 442817 [Multi-domain] Cd Length: 313 Bit Score: 40.27 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 284 ELDWTV----RRGEKWALSGENGAGKSTL-LSLVCAdnpqsYACDISLFGRKRGTGESIweikkhigYVSPEMHRAYLKN 358
Cdd:COG3598 1 PRRWLVpgllPEGGVTLLAGPPGTGKSFLaLQLAAA-----VAAGGPWLGRRVPPGKVL--------YLAAEDDRGELRR 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 359 -LPAIeivasGLHDSIglykrpqpeQMAVCEWWMDIfgiagLKDKPFLQLSSGEQRLALLARAFvkDPELLILDePL--- 434
Cdd:COG3598 68 rLKAL-----GADLGL---------PFADLDGRLRL-----LSLAGDLDDTDDLEALERAIEEE--GPDLVVID-PLarv 125
|
170 180 190
....*....|....*....|....*....|....
gi 2469828120 435 HGLDTYNR---RRVKKVIEAFCKRKDKTMIMVTH 465
Cdd:COG3598 126 FGGDENDAeemRAFLNPLDRLAERTGAAVLLVHH 159
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
22-65 |
2.85e-03 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 39.13 E-value: 2.85e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 2469828120 22 KPVTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYD 65
Cdd:cd03254 20 KDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQKGQILID 63
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
407-472 |
3.13e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 40.05 E-value: 3.13e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2469828120 407 LSSGEQ-------RLALlARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAFCkRKDKTMIMVTHYEsELPD 472
Cdd:PRK03918 789 LSGGERialglafRLAL-SLYLAGNIPLLILDEPTPFLDEERRRKLVDIMERYL-RKIPQVIIVSHDE-ELKD 858
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
277-465 |
3.58e-03 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 38.52 E-value: 3.58e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 277 DDRTILNELDWTVR----RGEKWALSGENGAGKSTLLSLVCAdnpqSYACDISLFGRKRGTGE-SIWeikkhigYVSPEM 351
Cdd:pfam13481 14 GLAAPPPPRRWLIKgllpAGGLGLLAGAPGTGKTTLALDLAA----AVATGKPWLGGPRVPEQgKVL-------YVSAEG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 352 hraylknlpaieiVASGLHDSIG--LYKRPQPEQMAVCEWWMDIfgiaglkdkPFLQLSSGEQRLAL----LARAF--VK 423
Cdd:pfam13481 83 -------------PADELRRRLRaaGADLDLPARLLFLSLVESL---------PLFFLDRGGPLLDAdvdaLEAALeeVE 140
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2469828120 424 DPELLILDePL---HGLDTYNRRRVKKVIEA---FCKRKDKTMIMVTH 465
Cdd:pfam13481 141 DPDLVVID-PLaraLGGDENSNSDVGRLVKAldrLARRTGATVLLVHH 187
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
407-472 |
3.67e-03 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 39.12 E-value: 3.67e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 407 LSSGEQRLALLARAFVKDPELLILDEPLHGLDTYNRRRVKKVI-EAFCkrkDKTMIMVTHYESELPD 472
Cdd:cd03288 157 FSVGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVmTAFA---DRTVVTIAHRVSTILD 220
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
144-204 |
3.83e-03 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 39.40 E-value: 3.83e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2469828120 144 LSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV---LSML 204
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLIshdLQML 222
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
396-484 |
3.89e-03 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 39.84 E-value: 3.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 396 IAGLKDKPFLQLS-----SGEQRLAL-LARAFVKDPELLILDEPLHGLDTYnrrrVKKVIEAFCKRKDKTMIMVTHyESE 469
Cdd:PLN03073 328 LAGLSFTPEMQVKatktfSGGWRMRIaLARALFIEPDLLLLDEPTNHLDLH----AVLWLETYLLKWPKTFIVVSH-ARE 402
|
90
....*....|....*
gi 2469828120 470 LPDTITNRIFLKRNQ 484
Cdd:PLN03073 403 FLNTVVTDILHLHGQ 417
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
24-207 |
4.42e-03 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 38.54 E-value: 4.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 24 VTATIGADEHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAT---------------------QTVYDNVKYIa 82
Cdd:PRK10247 26 ISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTlkpeiyrqqvsycaqtptlfgDTVYDNLIFP- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 83 frdtygaadanyyYQQRwnahdqDETPDVREMLGEIkdeqlknELFELfrIEPLLDKKIILLSSGELRKFQLTKTLLTAP 162
Cdd:PRK10247 105 -------------WQIR------NQQPDPAIFLDDL-------ERFAL--PDTILTKNIAELSGGEKQRISLIRNLQFMP 156
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2469828120 163 RVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILVLSMLDDI 207
Cdd:PRK10247 157 KVLLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEI 201
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
126-200 |
4.82e-03 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 38.82 E-value: 4.82e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 126 ELFELFRIEP--LLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELLFSLLERLTKMSSVQIILV 200
Cdd:cd03295 116 ELLALVGLDPaeFADRYPHELSGGQQQRVGVARALAADPPLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFV 192
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
416-485 |
5.13e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 39.49 E-value: 5.13e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 416 LLARAFVKDPELLILDEPLHGLDTYNRRRVKKVIEAfckrKDKTMIMVTHyeselpdtitNRIFLkrNQV 485
Cdd:PRK15064 165 LLAQALFSNPDILLLDEPTNNLDINTIRWLEDVLNE----RNSTMIIISH----------DRHFL--NSV 218
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
401-465 |
6.95e-03 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 38.76 E-value: 6.95e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2469828120 401 DKPFLQLSSGEQRLALLARAFVKDPELLILDEPLHGLDTynrrrvKKV--IEAFCKRKDKTMIMVTH 465
Cdd:TIGR03719 156 DADVTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDA------ESVawLERHLQEYPGTVVAVTH 216
|
|
| PRK10636 |
PRK10636 |
putative ABC transporter ATP-binding protein; Provisional |
274-312 |
8.95e-03 |
|
putative ABC transporter ATP-binding protein; Provisional
Pssm-ID: 236729 [Multi-domain] Cd Length: 638 Bit Score: 38.61 E-value: 8.95e-03
10 20 30
....*....|....*....|....*....|....*....
gi 2469828120 274 IRYDDRTILNELDWTVRRGEKWALSGENGAGKSTLLSLV 312
Cdd:PRK10636 9 IRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALL 47
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
32-198 |
9.25e-03 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 38.13 E-value: 9.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 32 EHIAIVGPNGGGKSLFVDTLTGKYPLREGTLQYDFFPSAtqtvYDNVKYIAFRDTYGAAdanyyYQqrwNAHDQDETPDV 111
Cdd:PRK13639 29 EMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPIK----YDKKSLLEVRKTVGIV-----FQ---NPDDQLFAPTV 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2469828120 112 RE-------MLGEIKDEQLK--NELFELFRIEPLLDKKIILLSSGELRKFQLTKTLLTAPRVLIMDNPFIGLDAPTRELL 182
Cdd:PRK13639 97 EEdvafgplNLGLSKEEVEKrvKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDPMGASQI 176
|
170
....*....|....*.
gi 2469828120 183 FSLLERLTKMSSVQII 198
Cdd:PRK13639 177 MKLLYDLNKEGITIII 192
|
|
| |
