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Conserved domains on  [gi|2468285848|ref|WP_276697505|]
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nickel ABC transporter permease [Dialister invisus]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 9-313 1.72e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 343.59  E-value: 1.72e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNedivVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:COG0601     5 ILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPR----ATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:COG0601    81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVGGDV-------SVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLI 241
Cdd:COG0601   161 WLPVSGRVSpwedfldALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468285848 242 TLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLR 313
Cdd:COG0601   241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 9-313 1.72e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 343.59  E-value: 1.72e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNedivVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:COG0601     5 ILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPR----ATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:COG0601    81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVGGDV-------SVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLI 241
Cdd:COG0601   161 WLPVSGRVSpwedfldALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468285848 242 TLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLR 313
Cdd:COG0601   241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 9-316 6.88e-71

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 222.27  E-value: 6.88e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNEdIVVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:PRK10352    5 ILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSN-LPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGIS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:PRK10352   84 FATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQ 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVGGDvSVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAF 248
Cdd:PRK10352  164 WLPAMGYG-GWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHI 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2468285848 249 GSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLRKAG 316
Cdd:PRK10352  243 GELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHE 310
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 121-314 4.42e-31

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 115.09  E-value: 4.42e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 121 AIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFalklnlfpivgGDVSVENLILPMVTLGVVMASKYTRQ 200
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----------ILSILGHGILPAIILALLGWAGYARL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 201 VRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDF 280
Cdd:pfam00528  70 IRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDY 149

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2468285848 281 QTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLRK 314
Cdd:pfam00528 150 PEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 103-292 4.49e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 4.49e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 103 LPATVILALASSVFMLLFAIPLGIYTAVKQNtWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLNLFPIVGgdvsvenL 182
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG-------L 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 183 ILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVF 262
Cdd:cd06261    73 GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2468285848 263 S----WPGLGFMVVQAITYRDFQTVQAVVLWIAF 292
Cdd:cd06261   153 GgeapGPGTGLLLIFAILFPGDLGVAAAVALILL 186
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 9-313 1.72e-118

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 343.59  E-value: 1.72e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNedivVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:COG0601     5 ILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPR----ATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:COG0601    81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVGGDV-------SVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLI 241
Cdd:COG0601   161 WLPVSGRVSpwedfldALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVV 240

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468285848 242 TLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLR 313
Cdd:COG0601   241 TVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRIR 312
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 9-316 6.88e-71

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 222.27  E-value: 6.88e-71
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNEdIVVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:PRK10352    5 ILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDYLRLSN-LPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGIS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:PRK10352   84 FATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSVYLQ 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVGGDvSVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAF 248
Cdd:PRK10352  164 WLPAMGYG-GWQHIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILRNASLPMITAVGMHI 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2468285848 249 GSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLRKAG 316
Cdd:PRK10352  243 GELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHE 310
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 12-313 1.49e-61

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 198.01  E-value: 1.49e-61
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  12 RLGQMVLVLLGISFITFCLVMLAPGDPVRqMIAGNEdivVSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFSFMM 91
Cdd:PRK15081    8 RLLGLIPTLLIVAVLVFLFVHLLPGDPAR-LAAGPE---ADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTSMVS 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  92 KKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLNLFP 171
Cdd:PRK15081   84 RRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELGWLP 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 172 IVGGDvSVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSL 251
Cdd:PRK15081  164 TVGAD-SWQHYILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFGFL 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468285848 252 LGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLR 313
Cdd:PRK15081  243 LGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLYAAINPAIR 304
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
12-315 9.20e-55

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 180.80  E-value: 9.20e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  12 RLGQMVLVLLGISFITFCLVMLAPGDPVRqmiagnedivvsqveidalrhelglDQPFLMQYLSWLGRMLHGNFGFSFMM 91
Cdd:COG4168     8 RLNLLLITLLILSLISFSLLYRDPLNPLS-------------------------DASLFSGYLFYLQNLLQGDFGISSIN 62

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  92 KKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLNLFP 171
Cdd:COG4168    63 GEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLGWLP 142

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 172 IVGG----------------DV--------------SVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARG 221
Cdd:COG4168   143 VSGRynllyeippvtgfaliDAwlsdspyrlkaiqsALQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAATRG 222

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 222 FSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVV 301
Cdd:COG4168   223 LSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVNILS 302

                         330
                  ....*....|....
gi 2468285848 302 DLSYNHLDPRLRKA 315
Cdd:COG4168   303 DILGALLNPLKRKE 316
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
9-313 2.89e-52

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 175.00  E-value: 2.89e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   9 IAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMiAGNEDIvvSQVEIDALRHELGLDQPFLMQYLSWLGRMLHGNFGFS 88
Cdd:PRK10914    5 ILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIM-AGERGI--SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGIS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  89 FMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLN 168
Cdd:PRK10914   82 LKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHWN 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 169 LFPIVG----------------------------GDV--SVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGAR 218
Cdd:PRK10914  162 LTPVSGrvsdmvflddsnpltgfmlidtaiwgedGNFidAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTAR 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 219 ARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAIN 298
Cdd:PRK10914  242 AKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVN 321

                         330
                  ....*....|....*
gi 2468285848 299 LVVDLSYNHLDPRLR 313
Cdd:PRK10914  322 LLVDLLYGVVNPRIR 336
oppB PRK09471
oligopeptide ABC transporter permease OppB;
7-313 1.43e-41

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 146.36  E-value: 1.43e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848   7 KQIAMRLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNEDIVVSqveIDALRHelgLDQPFLMQYLSWLGRMLHGNFG 86
Cdd:PRK09471    3 KFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMAN---IEAKYH---LNDPIMTQYFSYLKQLAHGDFG 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  87 FSFMMKK-PVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFAL 165
Cdd:PRK09471   77 PSFKYKDySVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLLVLIFAI 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 166 KLNLFPIVG-GDVSVENLILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLL 244
Cdd:PRK09471  157 TLHWLPGGGwNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYM 236

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2468285848 245 GLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLR 313
Cdd:PRK09471  237 GPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIR 305
PRK15110 PRK15110
peptide ABC transporter permease SapB;
73-303 6.53e-32

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 120.95  E-value: 6.53e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  73 YLSWLGRMLHGNFGFSFMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWADYIIRGFTFAGVSVPN 152
Cdd:PRK15110   44 WVFWFNGLLHWDFGVSSINGQPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPV 123

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 153 FWMGLMLLWIFALKLNLFPIVGG-DV-----------------------------SVENLILPMVTLGVVMASKYTRQVR 202
Cdd:PRK15110  124 FWLALLLTLFFSLTLGWLPVSGRfDLlyevkpvtgfalidawlsdspwrdemimsAIRHMILPVITLAVAPTTEVIRLMR 203

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 203 ATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQT 282
Cdd:PRK15110  204 ISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAA 283

                         250       260
                  ....*....|....*....|.
gi 2468285848 283 VQAVVLWIAFMYMAINLVVDL 303
Cdd:PRK15110  284 ISAGVMVVGSLVIIVNVLSDI 304
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 121-314 4.42e-31

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 115.09  E-value: 4.42e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 121 AIPLGIYTAVKQNTWADYIIRGFTFAGVSVPNFWMGLMLLWIFalklnlfpivgGDVSVENLILPMVTLGVVMASKYTRQ 200
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIA-----------ILSILGHGILPAIILALLGWAGYARL 69

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 201 VRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDF 280
Cdd:pfam00528  70 IRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGYDY 149

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2468285848 281 QTVQAVVLWIAFMYMAINLVVDLSYNHLDPRLRK 314
Cdd:pfam00528 150 PEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 12-312 1.88e-28

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 112.53  E-value: 1.88e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  12 RLGQMVLVLLGISFITFCLVMLAPGDPVRQMIA-------------GNEDIVVSQVE---------------------ID 57
Cdd:PRK15133    8 RLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAaiefgqagglpgaGGEGVRASHAQtgvgnisdsnyrggrgldpevIA 87

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  58 ALRHELGLDQPFLMQYLSWLGRMLHGNFGFSFMMKKPVLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKQNTWAD 137
Cdd:PRK15133   88 EITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSRFD 167

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 138 YIIRGFTFAGVSVPNFWMGLMLLWIFA--LKLNLFPIvGGDVSVENLILPM----------VTLGVVMA-----SKYTRQ 200
Cdd:PRK15133  168 VWSSAFIIIGYAIPAFLFAILLIVFFAggSYFDLFPL-RGLVSANFDSLPWyqkitdylwhITLPVLATviggfAALTML 246

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 201 VRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSL-LGGAAVVEIVFSWPGLGFMVVQAITYRD 279
Cdd:PRK15133  247 TKNSFLDEIRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMfFTGSLLIEVMFSLNGLGLLGYEATVSRD 326

                         330       340       350
                  ....*....|....*....|....*....|...
gi 2468285848 280 FQTVQAVVLWIAFMYMAINLVVDLSYNHLDPRL 312
Cdd:PRK15133  327 YPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 103-292 4.49e-17

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 77.70  E-value: 4.49e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 103 LPATVILALASSVFMLLFAIPLGIYTAVKQNtWADYIIRGFTFAGVSVPNFWMGLMLLWIFALKLNLFPIVGgdvsvenL 182
Cdd:cd06261     1 LLNTLLLALIATLLALVLGLLLGIILARKRG-KLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGWGILPG-------L 72

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 183 ILPMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVF 262
Cdd:cd06261    73 GLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                         170       180       190
                  ....*....|....*....|....*....|....
gi 2468285848 263 S----WPGLGFMVVQAITYRDFQTVQAVVLWIAF 292
Cdd:cd06261   153 GgeapGPGTGLLLIFAILFPGDLGVAAAVALILL 186
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 12-110 3.49e-15

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 70.33  E-value: 3.49e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  12 RLGQMVLVLLGISFITFCLVMLAPGDPVRQMIAGNedivVSQVEIDALRHELGLDQPFLMQYLSWL-----GRMLHGN-- 84
Cdd:pfam19300   8 RTLGAVVILLIISAVTFFLFYAIPRDPARLACGKN----CTPETLALIRHNLGLDKPIPVQYWHFLsgifaGRDFGAVgh 83

                          90       100       110
                  ....*....|....*....|....*....|.
gi 2468285848  85 -----FGFSFMMKKPVLDAVLEALPATVILA 110
Cdd:pfam19300  84 cpapcLGYSFANNEPVWDTIMDRFPTTLSLA 114
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 95-236 6.14e-10

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 58.97  E-value: 6.14e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848  95 VLDAVLEALPATVILALASSVFMLLFAIPLGIYTAVKqNTWADYIIRGFTFAGVSVPNFWMGLMLlwIFALKLNLFPIvg 174
Cdd:COG1173    70 VLSRLLYGARISLLVGLLAVLIALVIGVLLGLLAGYF-GGWVDAVLMRLVDVLLAFPSLLLAIAL--VAVLGPGLLNV-- 144

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2468285848 175 gdvsvenlilpMVTLGVVMASKYTRQVRATVLEELRQDYVMGARARGFSESHILWKEVLPNA 236
Cdd:COG1173   145 -----------ILALGLTGWPGYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNV 195
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 201-236 1.64e-04

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 42.83  E-value: 1.64e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 2468285848 201 VRATVLEELRQDYVMGARARGFSESHILWKEVLPNA 236
Cdd:COG4239   222 VRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNA 257
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 206-303 2.49e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.98  E-value: 2.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2468285848 206 LEELRQDYVMGARARGFSESHILWKEVLPNALLPLITLLGLAFGSLLGGAAVVEIVFSWPGLGFMVVQAITYRDFQTVQA 285
Cdd:COG0600   148 VRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIGLVVAELLGASSGLGYLILDARQLLDTDLVFA 227

                          90
                  ....*....|....*...
gi 2468285848 286 VVLWIAFMYMAINLVVDL 303
Cdd:COG0600   228 AILVIGLLGLLLDLLLRL 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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