NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2415962218|ref|WP_269207971|]
View 

MULTISPECIES: hypothetical protein [Thermoanaerobacter]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
1-28 4.63e-05

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member PRK06526:

Pssm-ID: 476819  Cd Length: 254  Bit Score: 37.16  E-value: 4.63e-05
                          10        20
                  ....*....|....*....|....*...
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLF 28
Cdd:PRK06526  154 LVKLGRYPLLIVDEVGYIPFEPEAANLF 181
 
Name Accession Description Interval E-value
PRK06526 PRK06526
transposase; Provisional
1-28 4.63e-05

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 37.16  E-value: 4.63e-05
                          10        20
                  ....*....|....*....|....*...
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLF 28
Cdd:PRK06526  154 LVKLGRYPLLIVDEVGYIPFEPEAANLF 181
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
1-29 6.90e-05

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 36.65  E-value: 6.90e-05
                          10        20
                  ....*....|....*....|....*....
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLFL 29
Cdd:pfam01695 148 LQQLLKPDVLILDEWGYLPLDQAEANLLF 176
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-29 1.54e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 35.53  E-value: 1.54e-04
                          10        20
                  ....*....|....*....|....*....
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLFL 29
Cdd:COG1484   155 LKRLAKVDLLILDELGYLPLDAEGAELLF 183
 
Name Accession Description Interval E-value
PRK06526 PRK06526
transposase; Provisional
1-28 4.63e-05

transposase; Provisional


Pssm-ID: 180607  Cd Length: 254  Bit Score: 37.16  E-value: 4.63e-05
                          10        20
                  ....*....|....*....|....*...
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLF 28
Cdd:PRK06526  154 LVKLGRYPLLIVDEVGYIPFEPEAANLF 181
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
1-29 6.90e-05

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 36.65  E-value: 6.90e-05
                          10        20
                  ....*....|....*....|....*....
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLFL 29
Cdd:pfam01695 148 LQQLLKPDVLILDEWGYLPLDQAEANLLF 176
PRK09183 PRK09183
transposase/IS protein; Provisional
8-28 1.27e-04

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 35.84  E-value: 1.27e-04
                          10        20
                  ....*....|....*....|.
gi 2415962218   8 RLLVVDEVGYLPLDNLGVNLF 28
Cdd:PRK09183  166 RLLIIDEIGYLPFSQEEANLF 186
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-29 1.54e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 35.53  E-value: 1.54e-04
                          10        20
                  ....*....|....*....|....*....
gi 2415962218   1 MRKYIRLRLLVVDEVGYLPLDNLGVNLFL 29
Cdd:COG1484   155 LKRLAKVDLLILDELGYLPLDAEGAELLF 183
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH