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Conserved domains on  [gi|2303419561|ref|WP_260154012|]
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helix-turn-helix domain-containing protein [Latilactobacillus curvatus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG4742 super family cl34811
Predicted transcriptional regulator, contains HTH domain [Transcription];
2-41 1.92e-03

Predicted transcriptional regulator, contains HTH domain [Transcription];


The actual alignment was detected with superfamily member COG4742:

Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 37.57  E-value: 1.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2303419561   2 PKTIRELADELGVSKQRIQQIIAKLSASKTPNKEGNRYVL 41
Cdd:COG4742    29 PKTRSELAESLDVSRSTILRQLKELEERGLIERDDGEYEL 68
 
Name Accession Description Interval E-value
COG4742 COG4742
Predicted transcriptional regulator, contains HTH domain [Transcription];
2-41 1.92e-03

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 37.57  E-value: 1.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2303419561   2 PKTIRELADELGVSKQRIQQIIAKLSASKTPNKEGNRYVL 41
Cdd:COG4742    29 PKTRSELAESLDVSRSTILRQLKELEERGLIERDDGEYEL 68
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
4-26 3.07e-03

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 34.49  E-value: 3.07e-03
                          10        20
                  ....*....|....*....|...
gi 2303419561   4 TIRELADELGVSKQRIQQIIAKL 26
Cdd:pfam12802  21 TVAELARRLGISKQTVSRLVKRL 43
 
Name Accession Description Interval E-value
COG4742 COG4742
Predicted transcriptional regulator, contains HTH domain [Transcription];
2-41 1.92e-03

Predicted transcriptional regulator, contains HTH domain [Transcription];


Pssm-ID: 443776 [Multi-domain]  Cd Length: 267  Bit Score: 37.57  E-value: 1.92e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 2303419561   2 PKTIRELADELGVSKQRIQQIIAKLSASKTPNKEGNRYVL 41
Cdd:COG4742    29 PKTRSELAESLDVSRSTILRQLKELEERGLIERDDGEYEL 68
MarR_2 pfam12802
MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a ...
4-26 3.07e-03

MarR family; The Mar proteins are involved in the multiple antibiotic resistance, a non-specific resistance system. The expression of the mar operon is controlled by a repressor, MarR. A large number of compounds induce transcription of the mar operon. This is thought to be due to the compound binding to MarR, and the resulting complex stops MarR binding to the DNA. With the MarR repression lost, transcription of the operon proceeds. The structure of MarR is known and shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.


Pssm-ID: 432797 [Multi-domain]  Cd Length: 60  Bit Score: 34.49  E-value: 3.07e-03
                          10        20
                  ....*....|....*....|...
gi 2303419561   4 TIRELADELGVSKQRIQQIIAKL 26
Cdd:pfam12802  21 TVAELARRLGISKQTVSRLVKRL 43
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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