|
Name |
Accession |
Description |
Interval |
E-value |
| PatZN |
COG1042 |
Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; |
4-700 |
0e+00 |
|
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
Pssm-ID: 440664 [Multi-domain] Cd Length: 708 Bit Score: 710.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 4 TMHSLHPLFFPQSVAIIGASSDPERIGGRPLRFLIESGFAAPIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAG 83
Cdd:COG1042 2 STRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 84 VEAALGDCIRKGVRCVQVLTAGFAELGSEGRALQDRLLAMCRAAGVRMVGPNSLGLLNVDTRFFATFSTAlnglQPRPGV 163
Cdd:COG1042 82 VPDVVEECGEKGVKAAVVISAGFAETGEEGAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPV----PPLPGN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 164 ISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEADVDVAECIAYLADDPQTQVICAAIESCRDGNRLRAALLKAAvAGK 243
Cdd:COG1042 158 IALVSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAA-RGK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 244 PVLVMKVGRTELGAAAASTHTGSLAGDDAVFDAVFAECGAYRPSSIEEMLDIAYLCATtGRMPPNADIGVVTGSGGIGVL 323
Cdd:COG1042 237 PVVVLKSGRSEAGARAAASHTGALAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALAR-QPPPRGRRLAIVTNSGGPGVL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 324 MADHAGDSGLSMSPLPPAAVAATLELLP-FAVAANPLDMTAQVTSvkGGVPRTLDAMLTHGPYGTVFaylahVGLSPQRF 402
Cdd:COG1042 316 AADALEDLGLELAELSEETQAALRAVLPpFASVGNPVDITGDADP--ERYAAALEALLADPNVDAVL-----VILTPTAM 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 403 ASSLDELGALR--LRHPDKDIVMVML---SAPEVNARLEAMRMPVFADPSRAVLAVAAAARMAERRRMLYQAVTHTGQGR 477
Cdd:COG1042 389 TDPEEVAEALIeaAKGSGKPVLASWMggdSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPASEDFDP 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 478 ALGQVDTEATAKKALALA--------------GLPMLPECLCANADEAVRAAEGVGFPVVAKISSPDIPHKTEVGGVLLN 543
Cdd:COG1042 469 DRERARAIIEAALAEGRGvlteaeakallaayGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLN 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 544 LPDAAAVRAAFDTLVSRARAAVPQARIEGVLVAPMLKGGVEVILGVHMDPTFGPMVMYGSGGTAVELFKDVAFASAPLNP 623
Cdd:COG1042 549 LRDAEAVRAAFEEILARVRAARPDARIDGVLVQPMVPGGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNE 628
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245317960 624 ARAQALVDRVRSSALLRGWRGAPPCDEAALVDALCRLSEFALAHReELVSVDINPLVVRAQGAVCLDAVIVTRPPAT 700
Cdd:COG1042 629 ALAREMIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLP-EILELDINPLLVVPEGVVAVDARIRLAPPAP 704
|
|
| AcCoA-syn-alpha |
TIGR02717 |
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ... |
8-446 |
8.90e-113 |
|
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.
Pssm-ID: 131764 [Multi-domain] Cd Length: 447 Bit Score: 347.76 E-value: 8.90e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 8 LHPLFFPQSVAIIGASSDPERIGGRPLRFLIESGFAAPIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAGVEAA 87
Cdd:TIGR02717 1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 88 LGDCIRKGVRCVQVLTAGFAELGSEGRALQDRLLAMCRAAGVRMVGPNSLGLLNVDTRFFATFSTALnglqPRPGVISLA 167
Cdd:TIGR02717 81 VEECGEKGVKGAVVITAGFKEVGEEGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTM----PKKGGIAFI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 168 TQSGAFGSCAYGMATLRGLGFSKIIATGNEADVDVAECIAYLADDPQTQVICAAIESCRDGNR-LRAAllKAAVAGKPVL 246
Cdd:TIGR02717 157 SQSGALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKfLKTA--REISKKKPIV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 247 VMKVGRTELGAAAASTHTGSLAGDDAVFDAVFAECGAYRPSSIEEMLDIAYLCATTgRMPPNADIGVVTGSGGIGVLMAD 326
Cdd:TIGR02717 235 VLKSGTSEAGAKAASSHTGALAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQ-PLPKGNRVAIITNAGGPGVIATD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 327 HAGDSGLSMSPLPPAAVAATLELLP-FAVAANPLDMTAQVTSVKGGvpRTLDAMLTHGPYGTVFA-YLAHVGLSPQRFAS 404
Cdd:TIGR02717 314 ACEENGLELAELSEATKNKLRNILPpEASIKNPVDVLGDATPERYA--KALKTVAEDENVDGVVVvLTPTAMTDPEEVAK 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2245317960 405 SLDElgaLRLRHPDKDIVMVMLSAPEVNA---RLEAMRMPVFADP 446
Cdd:TIGR02717 392 GIIE---GAKKSNEKPVVAGFMGGKSVDPakrILEENGIPNYTFP 433
|
|
| ATP-grasp_5 |
pfam13549 |
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ... |
496-694 |
1.51e-84 |
|
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.
Pssm-ID: 463918 [Multi-domain] Cd Length: 221 Bit Score: 265.88 E-value: 1.51e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 496 GLPMLPECLCANADEAVRAAEGVGFPVVAKISSPDIPHKTEVGGVLLNLPDAAAVRAAFDTLVSRARAAVPQARIEGVLV 575
Cdd:pfam13549 23 GIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAAYEEILERVRRYRPDARIEGVLV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 576 APMLKGGVEVILGVHMDPTFGPMVMYGSGGTAVELFKDVAFASAPLNPARAQALVDRVRSSALLRGWRGAPPCDEAALVD 655
Cdd:pfam13549 103 QPMAPGGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREMIRRTRAYKLLKGYRGEPPADLDALED 182
|
170 180 190
....*....|....*....|....*....|....*....
gi 2245317960 656 ALCRLSEFALAHrEELVSVDINPLVVRAQGAVCLDAVIV 694
Cdd:pfam13549 183 VLVRVSQLVIDF-PEIRELDINPLLADEDGVVALDARIR 220
|
|
| CoA_binding |
smart00881 |
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ... |
11-106 |
1.47e-15 |
|
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.
Pssm-ID: 214881 [Multi-domain] Cd Length: 100 Bit Score: 72.54 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 11 LFFPQ-SVAIIGASSDPERIGGRPLRFLIESG--FAAPIYPvNKSGAQIQGLASFSSVLDIPGP--VDQAIIAVPVAGVE 85
Cdd:smart00881 1 LLNPNtSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYP-GKVGPKVDGVPVYDSVAEAPEEtgVDVAVIFVPAEAAP 79
|
90 100
....*....|....*....|.
gi 2245317960 86 AALGDCIRKGVRCVQVLTAGF 106
Cdd:smart00881 80 DAIDEAIEAGIKGIVVITEGI 100
|
|
| PLN00125 |
PLN00125 |
Succinyl-CoA ligase [GDP-forming] subunit alpha |
50-253 |
4.06e-05 |
|
Succinyl-CoA ligase [GDP-forming] subunit alpha
Pssm-ID: 215066 [Multi-domain] Cd Length: 300 Bit Score: 46.11 E-value: 4.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 50 NKSGAQIQGLASFSSVLDIPGPV--DQAIIAVPVAGVEAALGDCIRKGVRCVQVLTAGFAElgsegRALQDRLLAMCRAA 127
Cdd:PLN00125 46 KKGGTEHLGLPVFNTVAEAKAETkaNASVIYVPPPFAAAAILEAMEAELDLVVCITEGIPQ-----HDMVRVKAALNRQS 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 128 GVRMVGPNSLGLLNVDTRFFATfstaLNGLQPRPGVISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEA--DVDVAEC 205
Cdd:PLN00125 121 KTRLIGPNCPGIIKPGECKIGI----MPGYIHKPGRIGIVSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPfnGTNFVDC 196
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2245317960 206 IAYLADDPQTQVICAAIESCRDGNRLRAALLKAAVAGKPVLVMKVGRT 253
Cdd:PLN00125 197 LEKFVKDPQTEGIILIGEIGGTAEEDAAAFIKESGTEKPVVAFIAGLT 244
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PatZN |
COG1042 |
Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; |
4-700 |
0e+00 |
|
Acyl-CoA synthetase (NDP forming) [Energy production and conversion];
Pssm-ID: 440664 [Multi-domain] Cd Length: 708 Bit Score: 710.36 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 4 TMHSLHPLFFPQSVAIIGASSDPERIGGRPLRFLIESGFAAPIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAG 83
Cdd:COG1042 2 STRSLDALFRPRSVAVIGASDRPGKVGGRVLRNLLEGGFKGKIYPVNPKYDEVLGLPCYPSVADLPEPPDLAVIAVPAET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 84 VEAALGDCIRKGVRCVQVLTAGFAELGSEGRALQDRLLAMCRAAGVRMVGPNSLGLLNVDTRFFATFSTAlnglQPRPGV 163
Cdd:COG1042 82 VPDVVEECGEKGVKAAVVISAGFAETGEEGAALEQELLEIARRYGMRLLGPNCLGLINPATGLNATFAPV----PPLPGN 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 164 ISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEADVDVAECIAYLADDPQTQVICAAIESCRDGNRLRAALLKAAvAGK 243
Cdd:COG1042 158 IALVSQSGALGTAILDWAAARGIGFSHFVSLGNEADVDFADLLDYLADDPDTRVILLYLEGIRDGRRFLSAARAAA-RGK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 244 PVLVMKVGRTELGAAAASTHTGSLAGDDAVFDAVFAECGAYRPSSIEEMLDIAYLCATtGRMPPNADIGVVTGSGGIGVL 323
Cdd:COG1042 237 PVVVLKSGRSEAGARAAASHTGALAGSDAVYDAAFRRAGVIRVDDLEELFDAAEALAR-QPPPRGRRLAIVTNSGGPGVL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 324 MADHAGDSGLSMSPLPPAAVAATLELLP-FAVAANPLDMTAQVTSvkGGVPRTLDAMLTHGPYGTVFaylahVGLSPQRF 402
Cdd:COG1042 316 AADALEDLGLELAELSEETQAALRAVLPpFASVGNPVDITGDADP--ERYAAALEALLADPNVDAVL-----VILTPTAM 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 403 ASSLDELGALR--LRHPDKDIVMVML---SAPEVNARLEAMRMPVFADPSRAVLAVAAAARMAERRRMLYQAVTHTGQGR 477
Cdd:COG1042 389 TDPEEVAEALIeaAKGSGKPVLASWMggdSVAEARRLLREAGIPTFRTPERAVRALAALVRYRRNQERLMETPASEDFDP 468
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 478 ALGQVDTEATAKKALALA--------------GLPMLPECLCANADEAVRAAEGVGFPVVAKISSPDIPHKTEVGGVLLN 543
Cdd:COG1042 469 DRERARAIIEAALAEGRGvlteaeakallaayGIPVVPTRLARSAEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLN 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 544 LPDAAAVRAAFDTLVSRARAAVPQARIEGVLVAPMLKGGVEVILGVHMDPTFGPMVMYGSGGTAVELFKDVAFASAPLNP 623
Cdd:COG1042 549 LRDAEAVRAAFEEILARVRAARPDARIDGVLVQPMVPGGVELIVGVKRDPVFGPVIMFGLGGIFVEVLKDVALRLPPLNE 628
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2245317960 624 ARAQALVDRVRSSALLRGWRGAPPCDEAALVDALCRLSEFALAHReELVSVDINPLVVRAQGAVCLDAVIVTRPPAT 700
Cdd:COG1042 629 ALAREMIRELRAAKLLRGYRGRPPADLDALADVLVRLSQLAADLP-EILELDINPLLVVPEGVVAVDARIRLAPPAP 704
|
|
| AcCoA-syn-alpha |
TIGR02717 |
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it ... |
8-446 |
8.90e-113 |
|
acetyl coenzyme A synthetase (ADP forming), alpha domain; Although technically reversible, it is believed that this group of ADP-dependent acetyl-CoA synthetases (ACS) act in the direction of acetate and ATP production in the organisms in which it has been characterized. In most species this protein exists as a fused alpha-beta domain polypeptide. In Pyrococcus and related species, however the domains exist as separate polypeptides. This model represents the alpha (N-terminal) domain. In Pyrococcus and related species there appears to have been the development of a paralogous family such that four other proteins are close relatives. In reference, one of these (along with its beta-domain partner) was characterized as ACS-II showing specificity for phenylacetyl-CoA. This model has been constructed to exclude these non-ACS-I paralogs. This may result in new, authentic ACS-I sequences falling below the trusted cutoff.
Pssm-ID: 131764 [Multi-domain] Cd Length: 447 Bit Score: 347.76 E-value: 8.90e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 8 LHPLFFPQSVAIIGASSDPERIGGRPLRFLIESGFAAPIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAGVEAA 87
Cdd:TIGR02717 1 LEHLFNPKSVAVIGASRDPGKVGYAIMKNLIEGGYKGKIYPVNPKAGEILGVKAYPSVLEIPDPVDLAVIVVPAKYVPQV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 88 LGDCIRKGVRCVQVLTAGFAELGSEGRALQDRLLAMCRAAGVRMVGPNSLGLLNVDTRFFATFSTALnglqPRPGVISLA 167
Cdd:TIGR02717 81 VEECGEKGVKGAVVITAGFKEVGEEGAELEQELVEIARKYGMRLLGPNCLGIINTHIKLNATFAPTM----PKKGGIAFI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 168 TQSGAFGSCAYGMATLRGLGFSKIIATGNEADVDVAECIAYLADDPQTQVICAAIESCRDGNR-LRAAllKAAVAGKPVL 246
Cdd:TIGR02717 157 SQSGALLTALLDWAEKNGVGFSYFVSLGNKADIDESDLLEYLADDPDTKVILLYLEGIKDGRKfLKTA--REISKKKPIV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 247 VMKVGRTELGAAAASTHTGSLAGDDAVFDAVFAECGAYRPSSIEEMLDIAYLCATTgRMPPNADIGVVTGSGGIGVLMAD 326
Cdd:TIGR02717 235 VLKSGTSEAGAKAASSHTGALAGSDEAYDAAFKQAGVIRADSIEELFDLARLLSNQ-PLPKGNRVAIITNAGGPGVIATD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 327 HAGDSGLSMSPLPPAAVAATLELLP-FAVAANPLDMTAQVTSVKGGvpRTLDAMLTHGPYGTVFA-YLAHVGLSPQRFAS 404
Cdd:TIGR02717 314 ACEENGLELAELSEATKNKLRNILPpEASIKNPVDVLGDATPERYA--KALKTVAEDENVDGVVVvLTPTAMTDPEEVAK 391
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 2245317960 405 SLDElgaLRLRHPDKDIVMVMLSAPEVNA---RLEAMRMPVFADP 446
Cdd:TIGR02717 392 GIIE---GAKKSNEKPVVAGFMGGKSVDPakrILEENGIPNYTFP 433
|
|
| ATP-grasp_5 |
pfam13549 |
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent ... |
496-694 |
1.51e-84 |
|
ATP-grasp domain; This family includes a diverse set of enzymes that possess ATP-dependent carboxylate-amine ligase activity.
Pssm-ID: 463918 [Multi-domain] Cd Length: 221 Bit Score: 265.88 E-value: 1.51e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 496 GLPMLPECLCANADEAVRAAEGVGFPVVAKISSPDIPHKTEVGGVLLNLPDAAAVRAAFDTLVSRARAAVPQARIEGVLV 575
Cdd:pfam13549 23 GIPVVPTRLARSPEEAVAAAEEIGYPVVLKIVSPDILHKSDVGGVRLNLRSAEAVRAAYEEILERVRRYRPDARIEGVLV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 576 APMLKGGVEVILGVHMDPTFGPMVMYGSGGTAVELFKDVAFASAPLNPARAQALVDRVRSSALLRGWRGAPPCDEAALVD 655
Cdd:pfam13549 103 QPMAPGGRELIVGVTRDPQFGPVIMFGLGGIAVEVLKDVAFRLPPLNMTLAREMIRRTRAYKLLKGYRGEPPADLDALED 182
|
170 180 190
....*....|....*....|....*....|....*....
gi 2245317960 656 ALCRLSEFALAHrEELVSVDINPLVVRAQGAVCLDAVIV 694
Cdd:pfam13549 183 VLVRVSQLVIDF-PEIRELDINPLLADEDGVVALDARIR 220
|
|
| Succ_CoA_lig |
pfam13607 |
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from ... |
161-298 |
3.06e-50 |
|
Succinyl-CoA ligase like flavodoxin domain; This domain contains the catalytic domain from Succinyl-CoA ligase alpha subunit and other related enzymes. A conserved histidine is involved in phosphoryl transfer.
Pssm-ID: 433345 [Multi-domain] Cd Length: 138 Bit Score: 171.88 E-value: 3.06e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 161 PGVISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEADVDVAECIAYLADDPQTQVICAAIESCRDGNRLRAAlLKAAV 240
Cdd:pfam13607 1 PGNIALVSQSGALGAALLDWARSRGIGFSKFVSLGNEADVDFADLLEYLADDPETRVILLYLEGIRDGRRFLRA-ARRAA 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 2245317960 241 AGKPVLVMKVGRTELGAAAASTHTGSLAGDDAVFDAVFAECGAYRPSSIEEMLDIAYL 298
Cdd:pfam13607 80 RRKPVVVLKAGRSEAGARAAASHTGALAGSDAVYDAAFRQAGVIRVDDLEELFDAAEA 137
|
|
| CoA_binding_2 |
pfam13380 |
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ... |
16-141 |
2.23e-18 |
|
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.
Pssm-ID: 433162 [Multi-domain] Cd Length: 116 Bit Score: 81.43 E-value: 2.23e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 16 SVAIIGASSDPERIGGRPLRFLIESGFaaPIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAGVEAALGDCIRKG 95
Cdd:pfam13380 2 TIAVVGASPNPGRPGYKVARYLLEHGY--PVIPVNPKAKEILGEPVYPSLADPPEPVDLVDVFRPPEAVPEIVEEALALG 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2245317960 96 VRCVqVLTAGfaelgsegrALQDRLLAMCRAAGVRMVGPNSLGLLN 141
Cdd:pfam13380 80 AKAV-WLQPG---------IENEEAAAIARAAGIRVVGDRCLGVEH 115
|
|
| CoA_binding |
smart00881 |
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ... |
11-106 |
1.47e-15 |
|
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.
Pssm-ID: 214881 [Multi-domain] Cd Length: 100 Bit Score: 72.54 E-value: 1.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 11 LFFPQ-SVAIIGASSDPERIGGRPLRFLIESG--FAAPIYPvNKSGAQIQGLASFSSVLDIPGP--VDQAIIAVPVAGVE 85
Cdd:smart00881 1 LLNPNtSVAVVGASGNLGSFGLAVMRNLLEYGtkFVGGVYP-GKVGPKVDGVPVYDSVAEAPEEtgVDVAVIFVPAEAAP 79
|
90 100
....*....|....*....|.
gi 2245317960 86 AALGDCIRKGVRCVQVLTAGF 106
Cdd:smart00881 80 DAIDEAIEAGIKGIVVITEGI 100
|
|
| YccU |
COG1832 |
Predicted CoA-binding protein [General function prediction only]; |
16-132 |
1.29e-08 |
|
Predicted CoA-binding protein [General function prediction only];
Pssm-ID: 441437 [Multi-domain] Cd Length: 138 Bit Score: 53.98 E-value: 1.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 16 SVAIIGASSDPERIGGRPLRFLIESGFAapIYPVNKSGAQIQGLASFSSVLDIPGPVDQAIIAVPVAGVEAALGDCIRKG 95
Cdd:COG1832 18 TIAVVGLSPNPERPSYYVAKYLQRHGYR--VIPVNPGAKEILGEKVYASLADIPEPVDIVDVFRRSEAVPEIVDEAIAIG 95
|
90 100 110
....*....|....*....|....*....|....*..
gi 2245317960 96 VRCVqvltagFAELGSEGRALQDRLlamcRAAGVRMV 132
Cdd:COG1832 96 AKVV------WLQLGVVNEEAAERA----EAAGLDVV 122
|
|
| Ligase_CoA_2 |
pfam19045 |
Ligase-CoA domain; This domain is related to pfam00549 and adopts a flavodoxin fold. |
313-431 |
3.32e-07 |
|
Ligase-CoA domain; This domain is related to pfam00549 and adopts a flavodoxin fold.
Pssm-ID: 408815 Cd Length: 162 Bit Score: 50.72 E-value: 3.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 313 VVTGSGGIGVLMADHAGDSGLSMSPLPPAAVAATLELL-PFAVAANPLDMTAqvtsvkGGVPRTLDAMLTHG---P--YG 386
Cdd:pfam19045 3 IITGAGGSGVLLSDACVDNGLTLMAIPPDLDAAFRKFIpPFGAAGNPVDITG------GEPPSTYEATIRLGledPriHA 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2245317960 387 TVFAYLAHVGLSPQRFASSLDEL-GALRLRHPDKDIVMVMLSAPEV 431
Cdd:pfam19045 77 LILGYWHTIVTPPMVFAELMVRVvEEMRAKGIDKPVVASLAGDVEV 122
|
|
| CoA_binding |
pfam02629 |
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins ... |
16-105 |
3.15e-06 |
|
CoA binding domain; This domain has a Rossmann fold and is found in a number of proteins including succinyl CoA synthetases, malate and ATP-citrate ligases.
Pssm-ID: 396961 [Multi-domain] Cd Length: 97 Bit Score: 46.05 E-value: 3.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 16 SVAIIGASSDPERIGGRPLRFLIESGFAApIYPVN--KSGAQIQGLASFSSVLDIPG--PVDQAIIAVPVAGVEAALGDC 91
Cdd:pfam02629 5 KVIVIGAGGLGIQGLNYHFIQMLGYGIKM-VFGVNpgKGGTEILGIPVYNSVDELEEktGVDVAVITVPAPFAQEAIDEL 83
|
90
....*....|....
gi 2245317960 92 IRKGVRCVQVLTAG 105
Cdd:pfam02629 84 VDAGIKGIVNITPG 97
|
|
| SucD |
COG0074 |
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA ... |
51-218 |
4.55e-06 |
|
Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Succinyl-CoA synthetase, alpha subunit is part of the Pathway/BioSystem: TCA cycle
Pssm-ID: 439844 [Multi-domain] Cd Length: 288 Bit Score: 48.90 E-value: 4.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 51 KSGAQIQGLASFSSVLDI--PGPVDQAIIAVPVAGVEAALGDCIRKGVRCVQVLTagfaelgsEGRALQD--RLLAMCRA 126
Cdd:COG0074 42 KGGQTVLGVPVFDTVAEAveETGADASVIFVPPPFAADAILEAIDAGIKLIVCIT--------EGIPVLDmvRVKRYAKA 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 127 AGVRMVGPNSLGLLNVDtrffatfsTALNGLQP----RPGVISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEADV-- 200
Cdd:COG0074 114 KGTRLIGPNCPGIITPG--------ECKLGIMPghifKPGRVGIVSRSGTLTYEAVWQLTQAGLGQSTCVGIGGDPIIgt 185
|
170
....*....|....*...
gi 2245317960 201 DVAECIAYLADDPQTQVI 218
Cdd:COG0074 186 SFIDVLELFEEDPETEAI 203
|
|
| PLN00125 |
PLN00125 |
Succinyl-CoA ligase [GDP-forming] subunit alpha |
50-253 |
4.06e-05 |
|
Succinyl-CoA ligase [GDP-forming] subunit alpha
Pssm-ID: 215066 [Multi-domain] Cd Length: 300 Bit Score: 46.11 E-value: 4.06e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 50 NKSGAQIQGLASFSSVLDIPGPV--DQAIIAVPVAGVEAALGDCIRKGVRCVQVLTAGFAElgsegRALQDRLLAMCRAA 127
Cdd:PLN00125 46 KKGGTEHLGLPVFNTVAEAKAETkaNASVIYVPPPFAAAAILEAMEAELDLVVCITEGIPQ-----HDMVRVKAALNRQS 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2245317960 128 GVRMVGPNSLGLLNVDTRFFATfstaLNGLQPRPGVISLATQSGAFGSCAYGMATLRGLGFSKIIATGNEA--DVDVAEC 205
Cdd:PLN00125 121 KTRLIGPNCPGIIKPGECKIGI----MPGYIHKPGRIGIVSRSGTLTYEAVFQTTAVGLGQSTCVGIGGDPfnGTNFVDC 196
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 2245317960 206 IAYLADDPQTQVICAAIESCRDGNRLRAALLKAAVAGKPVLVMKVGRT 253
Cdd:PLN00125 197 LEKFVKDPQTEGIILIGEIGGTAEEDAAAFIKESGTEKPVVAFIAGLT 244
|
|
| |
