|
Name |
Accession |
Description |
Interval |
E-value |
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
107-370 |
9.09e-36 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 136.31 E-value: 9.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 107 ALAVIVPLSVLAAELPHRRLQKV---ARTARRIESGDLTARTGEsRGDDEITAISATVDSMADSLhQRLLTE-------- 175
Cdd:NF040691 194 GLALVVLLGLIAWLVTRQVVAPVrsaARTAERFAAGDLSERMPV-KGEDDLARLARSFNQMADSL-QRQIRQleelsrlq 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 176 QRFTADVAHELRTPLMGLVTASELLPEGE---------ATELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPL 243
Cdd:NF040691 272 QRFVSDVSHELRTPLTTIRMAADVIHDSRddfdpatarSAELLHTELDRFESLLSDLLEISRFDAGAaelDVEPVDLRPL 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 244 AEAVSESL----ARTGQQTRFTAADALC-AETDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFP 313
Cdd:NF040691 352 VRRVVDALrqlaERAGVELRVDAPGTPVvAEVDPRRVERVLRNLVVNAIEHGEGKPVVVTVAQDDTAvavtvRDHGVGLK 431
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 314 PELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:NF040691 432 PGEVALVFDRFWRADPARARttgGTGLGLAIALEDARLHGGWLEAWGRPGQGSQFRLTLP 491
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
69-370 |
1.97e-35 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 131.95 E-value: 1.97e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 69 MWAARTYRGEPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGES 148
Cdd:COG0642 4 LLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 149 RGDDEITAISATVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASELLPEG------EATELVRDRVRVLRTLVED 222
Cdd:COG0642 84 LLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEldeeqrEYLETILRSADRLLRLIND 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 223 LLEISRLDAGGERAESRRVPLAEAVSESLA-------RTGQQTRFTAADALC-AETDPRRLDRIVTNLVVNAHRHGRAPV 294
Cdd:COG0642 164 LLDLSRLEAGKLELEPEPVDLAELLEEVVElfrplaeEKGIELELDLPDDLPtVRGDPDRLRQVLLNLLSNAIKYTPEGG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 295 EVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPER-GRGHGLGLTIALGQAEVIGASLSFANASDGGAVATL 367
Cdd:COG0642 244 TVTVSVRREGDrvrisvEDTGPGIPPEDLERIFEPFFRTDPSRrGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTV 323
|
...
gi 2225590578 368 RLP 370
Cdd:COG0642 324 TLP 326
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
97-370 |
1.11e-21 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 96.05 E-value: 1.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 97 DRHMWKYSLLALAVIVPLSVLAAELPHR----RLQKVARTARRIESGDLTARTgESRGDDEITAISATVDSMADSLHQRL 172
Cdd:NF012163 159 DSQQKRASWLIVALALLLAALAAFLLARgllaPVKRLVEATHRLAAGDYTTRV-TPTSNDELGKLAQDFNQLASTLEKNE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 173 LTEQRFTADVAHELRTPLMGLVTASELLPEG------EATELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPL 243
Cdd:NF012163 238 QMRRDFMADISHELRTPLAVLRAELEAIQDGirkftpESLDSLQAEVGTLTKLVDDLHDLSMSDEGAlayQKASVDLVPL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 244 ----AEAVSESLARTGQQTRFTAADALCAETDPRRLDRIVTNLVVNAHRHG------RAPVEVTVAGTTVTVRDHGPGFP 313
Cdd:NF012163 318 leveGGAFRERFASAGLELEVSLPDSSLVFGDRDRLMQLFNNLLENSLRYTdsggslHISASQRPKEVTLTVADSAPGVS 397
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 314 PELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:NF012163 398 DEQLARLFERFYRVEVSRNRasgGSGLGLAISLNIVQAHGGTLHAAHSPLGGLRIVVTLP 457
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
80-370 |
2.14e-19 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 88.98 E-value: 2.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 80 VAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGESRGDDEITAISA 159
Cdd:TIGR01386 146 ITVALDINAHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRAPAELRELAQ 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 160 TVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASEL-------------LPEGEATELVRdrvrvLRTLVEDLL-- 224
Cdd:TIGR01386 226 SFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQValsqprtgeeyreVLESNLEELER-----LSRMVSDMLfl 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 225 ----------EISRLDAGGERAESRRV--PLAEAVSESLARTGQQTrftaadalcAETDPRRLDRIVTNLVVNAHRHgrA 292
Cdd:TIGR01386 301 aradngqlalERVRLDLAAELAKVAEYfePLAEERGVRIRVEGEGL---------VRGDPQMFRRAISNLLSNALRH--T 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 293 PVEVTVAGTTVTVRDH--------GPGFPPELLNDGPQRFRTGAPER---GRGHGLGLTIALGQAEVIGASLSfANASDG 361
Cdd:TIGR01386 370 PDGGTITVRIERRSDEvrvsvsnpGPGIPPEHLSRLFDRFYRVDPARsnsGEGTGLGLAIVRSIMEAHGGRAS-AESPDG 448
|
....*....
gi 2225590578 362 GAVATLRLP 370
Cdd:TIGR01386 449 KTRFILRFP 457
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
85-368 |
2.82e-19 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 88.94 E-value: 2.82e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 85 DMTADLLTRRALDrhmWkysLLALAVIVPL--SVLAAELphRRLQKVARTARRiesgdltaRTGESRGDDEITAISATVD 162
Cdd:PRK10337 154 DMALAIVAGQLIP---W---LVALPIMLIIlmVLLGREL--APLKKLALALRM--------RDPDSETPLNATGVPSEVR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 163 SMADSL-------HQRLLTEQRFTADVAHELRTPLMGLVTASELLPEGEATELVRDRV---------RVLRtLVEDLLEI 226
Cdd:PRK10337 218 PLVEALnqlfartHAMMVRERRFTSDAAHELRSPLAALKVQTEVAQLSDDDPQARKKAllqlhagidRATR-LVDQLLTL 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 227 SRLDAGGERAESRRVPLAEAVSESLA---RTGQQTRFTAADALCAETDPRR-----LDRIVTNLVVNAHR--HGRAPVEV 296
Cdd:PRK10337 297 SRLDSLDNLQDVAEIPLEDLLQSAVMdiyHTAQQAGIDVRLTLNAHPVIRTgqpllLSLLVRNLLDNAIRysPQGSVVDV 376
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2225590578 297 TVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLR 368
Cdd:PRK10337 377 TLNARNFTVRDNGPGVTPEALARIGERFYRPPGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
270-370 |
1.73e-14 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 68.93 E-value: 1.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 270 TDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIALG 344
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGEltltvEDNGIGIPPEDLPRIFEPFSTADKRGGGGTGLGLSIVRK 80
|
90 100
....*....|....*....|....*.
gi 2225590578 345 QAEVIGASLSFANASDGGAVATLRLP 370
Cdd:pfam02518 81 LVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
270-370 |
1.14e-13 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 66.52 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 270 TDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPER--GRGHGLGLTI 341
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDhveitvEDNGPGIPPEDLEKIFEPFFRTDKRSrkIGGTGLGLSI 80
|
90 100
....*....|....*....|....*....
gi 2225590578 342 ALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
271-370 |
6.68e-11 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 59.04 E-value: 6.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 271 DPRRLDRIVTNLVVNAHRH----GRAP---VEVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLT 340
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFtpdgGRIRcilEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRahgGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 2225590578 341 IALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| ActS_PrrB_HisK |
NF033792 |
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, ... |
163-370 |
3.00e-09 |
|
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, found in alpha-proteobacteria, shows strong sequence conservation, including the notable motif [VA]AAAAHELGTPxTI. It always acts as a partner to an ActR/PrrA/RegA family global response regulator transcription factor in a two-component sensory transduction system. Lineage-specific names and gene symbols given to this histidine kinase reflect downstream regulator changes such as entry into stationary phase, anaerobic expression of photosynthesis genes, and survival of exposure to low pH.
Pssm-ID: 468186 [Multi-domain] Cd Length: 423 Bit Score: 58.30 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 163 SMADSL---HQRLLTEQRFT------ADVAHELRTPLMGL-VTASELLPEGEATELVRDRVRVLRTLVEDLLEI-SRLDA 231
Cdd:NF033792 181 RLSDALaatELVLAREQHLSaldglaAAAAHELGTPLATIaLVAKELERELPDDPPLREDAELLRSQAERCRDIlRRLTS 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 232 GGERAES--RRVPLAEAVSESLA--RT-GQQTRFTAADALCAETDPRRLDRIV---TNLVVN----AHRHGRAPVEVTVA 299
Cdd:NF033792 261 LGEEGDAhlDRLPLSALIEEAAAphRGfGKEIEVVVAGDPGEEPVIRRNPEILyglGNLIENavdfARSTVTVTASWDAE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 300 GTTVTVRDHGPGFPPELLNdgpqrfRTGAP-----------ERGRGHGLGLTIALGQAEVIGASLSFANASD--GGAVAT 366
Cdd:NF033792 341 SVTITIEDDGPGFPPDVLS------RIGEPyvttrrgeerrPGGGGLGLGLFIAKTLLERSGATVTFANRPPpeGGAVVT 414
|
....
gi 2225590578 367 LRLP 370
Cdd:NF033792 415 VRWP 418
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
106-370 |
9.84e-09 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 56.16 E-value: 9.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 106 LALAVIVPLSVLAaelphrrlqkvaRTARRIESGDLTARTGESRGDD-EITAISATVDSMADSLHQRLLTEQRFTADVAH 184
Cdd:NF012226 80 LAQRFIVPINFLA------------DAAKKISQGDLSARAEDSQIHSaEISELMHNFNDMAQKLESSVKNAQVWNAAIAH 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 185 ELRTP-------LMGLV----TASELLPEGeatelVRDRVRVLRTLVEDLLEISRLDAGGERAESRRVPLAEAVSESL-- 251
Cdd:NF012226 148 ELRTPitilqgrLQGILdgvfEPDPALFKS-----LLNQVEGLSHLVEDLRTLSLVENQQLRLNYESVDLKDSIEKVLkm 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 252 -------ARTGQQTRFTAADALCaetDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFPPELLND 319
Cdd:NF012226 223 fedrleqAQLTIVLNLTATPVFC---DRRRIEQVLIALIDNAIRYANAGKLKISSSVIQDDwilqiEDEGPGIAEEYQQD 299
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 320 GPQRFRTGAPERGR---GHGLGLtiALGQAEVIG--ASLSFANaSDGGAVATLRLP 370
Cdd:NF012226 300 LFNPFFRLEQSRNKefgGTGLGL--AVVHAIVIAhkGSIEYSN-SQGNSVFTIKLP 352
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
169-286 |
1.47e-05 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 47.05 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 169 HQRLLTEQR-FTADVAHELRTPLMGLVTASELLPEG--EATELVRDRVRVLRT-------LVEDLLEISRLDAGGERAES 238
Cdd:NF033092 365 QEKIEQERReFVANVSHELRTPLTTMRSYLEALADGawKDPELAPRFLGVTQNetermirLVNDLLQLSRMDSKDYKLNK 444
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 239 RRVPLAEAVSESLAR----TGQQ----TRFTAADALCAETDPRRLDRIVTNLVVNA 286
Cdd:NF033092 445 EWVNFNEFFNYIIDRfemiLKNKnitfKREFPKRDLWVEIDTDKITQVLDNIISNA 500
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MtrAB_MtrB |
NF040691 |
MtrAB system histidine kinase MtrB; |
107-370 |
9.09e-36 |
|
MtrAB system histidine kinase MtrB;
Pssm-ID: 468655 [Multi-domain] Cd Length: 507 Bit Score: 136.31 E-value: 9.09e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 107 ALAVIVPLSVLAAELPHRRLQKV---ARTARRIESGDLTARTGEsRGDDEITAISATVDSMADSLhQRLLTE-------- 175
Cdd:NF040691 194 GLALVVLLGLIAWLVTRQVVAPVrsaARTAERFAAGDLSERMPV-KGEDDLARLARSFNQMADSL-QRQIRQleelsrlq 271
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 176 QRFTADVAHELRTPLMGLVTASELLPEGE---------ATELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPL 243
Cdd:NF040691 272 QRFVSDVSHELRTPLTTIRMAADVIHDSRddfdpatarSAELLHTELDRFESLLSDLLEISRFDAGAaelDVEPVDLRPL 351
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 244 AEAVSESL----ARTGQQTRFTAADALC-AETDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFP 313
Cdd:NF040691 352 VRRVVDALrqlaERAGVELRVDAPGTPVvAEVDPRRVERVLRNLVVNAIEHGEGKPVVVTVAQDDTAvavtvRDHGVGLK 431
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 314 PELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:NF040691 432 PGEVALVFDRFWRADPARARttgGTGLGLAIALEDARLHGGWLEAWGRPGQGSQFRLTLP 491
|
|
| BaeS |
COG0642 |
Signal transduction histidine kinase [Signal transduction mechanisms]; |
69-370 |
1.97e-35 |
|
Signal transduction histidine kinase [Signal transduction mechanisms];
Pssm-ID: 440407 [Multi-domain] Cd Length: 328 Bit Score: 131.95 E-value: 1.97e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 69 MWAARTYRGEPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGES 148
Cdd:COG0642 4 LLLLLVLLLLLLLLLLLALLLLLLLLLLLALLLLLALLLLLLLLLLLLLLLALALLALLLLLLLLLLLLLLLLLLLLLLL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 149 RGDDEITAISATVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASELLPEG------EATELVRDRVRVLRTLVED 222
Cdd:COG0642 84 LLLLLLLLLLLLLLALLLLLEEANEAKSRFLANVSHELRTPLTAIRGYLELLLEEldeeqrEYLETILRSADRLLRLIND 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 223 LLEISRLDAGGERAESRRVPLAEAVSESLA-------RTGQQTRFTAADALC-AETDPRRLDRIVTNLVVNAHRHGRAPV 294
Cdd:COG0642 164 LLDLSRLEAGKLELEPEPVDLAELLEEVVElfrplaeEKGIELELDLPDDLPtVRGDPDRLRQVLLNLLSNAIKYTPEGG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 295 EVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPER-GRGHGLGLTIALGQAEVIGASLSFANASDGGAVATL 367
Cdd:COG0642 244 TVTVSVRREGDrvrisvEDTGPGIPPEDLERIFEPFFRTDPSRrGGGTGLGLAIVKRIVELHGGTIEVESEPGKGTTFTV 323
|
...
gi 2225590578 368 RLP 370
Cdd:COG0642 324 TLP 326
|
|
| KdpD |
COG2205 |
K+-sensing histidine kinase KdpD [Signal transduction mechanisms]; |
177-370 |
4.41e-31 |
|
K+-sensing histidine kinase KdpD [Signal transduction mechanisms];
Pssm-ID: 441807 [Multi-domain] Cd Length: 239 Bit Score: 118.09 E-value: 4.41e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 177 RFTADVAHELRTPLMGLVTASELLPEGEAT---------ELVRDRVRVLRTLVEDLLEISRLDAGGERAESRRVPLAEAV 247
Cdd:COG2205 18 EFLANVSHELRTPLTSILGAAELLLDEEDLspeerrellEIIRESAERLLRLIEDLLDLSRLESGKLSLELEPVDLAELL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 248 SESLARTGQQTR--------FTAADALCAETDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVR------DHGPGFP 313
Cdd:COG2205 98 EEAVEELRPLAEekgirlelDLPPELPLVYADPELLEQVLANLLDNAIKYSPPGGTITISARREGDGvrisvsDNGPGIP 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 2225590578 314 PELLNDGPQRFRTGAPERG-RGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG2205 178 EEELERIFERFYRGDNSRGeGGTGLGLAIVKRIVEAHGGTIWVESEPGGGTTFTVTLP 235
|
|
| WalK |
COG5002 |
Sensor histidine kinase WalK [Signal transduction mechanisms]; |
78-370 |
7.04e-28 |
|
Sensor histidine kinase WalK [Signal transduction mechanisms];
Pssm-ID: 444026 [Multi-domain] Cd Length: 390 Bit Score: 112.72 E-value: 7.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 78 EPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTgesRGDDEITAI 157
Cdd:COG5002 63 LLLLALLLLLLLLLLLLALALLLLALLLLLLLLLLLLALLILLLLLALLILLAALLLLLSELLLLLLL---LGRLSLRLS 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 158 SATVDSMADSLHQRLLTEQR--------FTADVAHELRTPLMGLVTASELLPEGEA--TELVRDRVRV-------LRTLV 220
Cdd:COG5002 140 ALLLGLLLLAAVERDITELErleqmrreFVANVSHELRTPLTSIRGYLELLLDGAAddPEERREYLEIileeaerLSRLV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 221 EDLLEISRLDAGGERAESRRVPLAEAVSESLARTGQQ--------TRFTAADALCAETDPRRLDRIVTNLVVNAHRHGRA 292
Cdd:COG5002 220 NDLLDLSRLESGELKLEKEPVDLAELLEEVVEELRPLaeekgielELDLPEDPLLVLGDPDRLEQVLTNLLDNAIKYTPE 299
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 293 PVEVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAEVIGASLSFANASDGGA 363
Cdd:COG5002 300 GGTITVSLREEDDqvrisvRDTGIGIPEEDLPRIFERFYRVDKSRSRetgGTGLGLAIVKHIVEAHGGRIWVESEPGKGT 379
|
....*..
gi 2225590578 364 VATLRLP 370
Cdd:COG5002 380 TFTITLP 386
|
|
| BaeS_SmeS |
NF012163 |
sensor histidine kinase efflux regulator BaeS; |
97-370 |
1.11e-21 |
|
sensor histidine kinase efflux regulator BaeS;
Pssm-ID: 411086 [Multi-domain] Cd Length: 457 Bit Score: 96.05 E-value: 1.11e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 97 DRHMWKYSLLALAVIVPLSVLAAELPHR----RLQKVARTARRIESGDLTARTgESRGDDEITAISATVDSMADSLHQRL 172
Cdd:NF012163 159 DSQQKRASWLIVALALLLAALAAFLLARgllaPVKRLVEATHRLAAGDYTTRV-TPTSNDELGKLAQDFNQLASTLEKNE 237
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 173 LTEQRFTADVAHELRTPLMGLVTASELLPEG------EATELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPL 243
Cdd:NF012163 238 QMRRDFMADISHELRTPLAVLRAELEAIQDGirkftpESLDSLQAEVGTLTKLVDDLHDLSMSDEGAlayQKASVDLVPL 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 244 ----AEAVSESLARTGQQTRFTAADALCAETDPRRLDRIVTNLVVNAHRHG------RAPVEVTVAGTTVTVRDHGPGFP 313
Cdd:NF012163 318 leveGGAFRERFASAGLELEVSLPDSSLVFGDRDRLMQLFNNLLENSLRYTdsggslHISASQRPKEVTLTVADSAPGVS 397
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 314 PELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:NF012163 398 DEQLARLFERFYRVEVSRNRasgGSGLGLAISLNIVQAHGGTLHAAHSPLGGLRIVVTLP 457
|
|
| cztS_silS_copS |
TIGR01386 |
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain ... |
80-370 |
2.14e-19 |
|
heavy metal sensor kinase; Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.
Pssm-ID: 273593 [Multi-domain] Cd Length: 457 Bit Score: 88.98 E-value: 2.14e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 80 VAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGESRGDDEITAISA 159
Cdd:TIGR01386 146 ITVALDINAHTHLLDALRKWLILIAVLLVLLTALLGWWITRLGLEPLRRLSAVAARISPESLDQRLDPSRAPAELRELAQ 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 160 TVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASEL-------------LPEGEATELVRdrvrvLRTLVEDLL-- 224
Cdd:TIGR01386 226 SFNAMLGRLEDAFQRLSQFSADLAHELRTPLTNLLGQTQValsqprtgeeyreVLESNLEELER-----LSRMVSDMLfl 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 225 ----------EISRLDAGGERAESRRV--PLAEAVSESLARTGQQTrftaadalcAETDPRRLDRIVTNLVVNAHRHgrA 292
Cdd:TIGR01386 301 aradngqlalERVRLDLAAELAKVAEYfePLAEERGVRIRVEGEGL---------VRGDPQMFRRAISNLLSNALRH--T 369
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 293 PVEVTVAGTTVTVRDH--------GPGFPPELLNDGPQRFRTGAPER---GRGHGLGLTIALGQAEVIGASLSfANASDG 361
Cdd:TIGR01386 370 PDGGTITVRIERRSDEvrvsvsnpGPGIPPEHLSRLFDRFYRVDPARsnsGEGTGLGLAIVRSIMEAHGGRAS-AESPDG 448
|
....*....
gi 2225590578 362 GAVATLRLP 370
Cdd:TIGR01386 449 KTRFILRFP 457
|
|
| PRK10337 |
PRK10337 |
sensor protein QseC; Provisional |
85-368 |
2.82e-19 |
|
sensor protein QseC; Provisional
Pssm-ID: 182388 [Multi-domain] Cd Length: 449 Bit Score: 88.94 E-value: 2.82e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 85 DMTADLLTRRALDrhmWkysLLALAVIVPL--SVLAAELphRRLQKVARTARRiesgdltaRTGESRGDDEITAISATVD 162
Cdd:PRK10337 154 DMALAIVAGQLIP---W---LVALPIMLIIlmVLLGREL--APLKKLALALRM--------RDPDSETPLNATGVPSEVR 217
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 163 SMADSL-------HQRLLTEQRFTADVAHELRTPLMGLVTASELLPEGEATELVRDRV---------RVLRtLVEDLLEI 226
Cdd:PRK10337 218 PLVEALnqlfartHAMMVRERRFTSDAAHELRSPLAALKVQTEVAQLSDDDPQARKKAllqlhagidRATR-LVDQLLTL 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 227 SRLDAGGERAESRRVPLAEAVSESLA---RTGQQTRFTAADALCAETDPRR-----LDRIVTNLVVNAHR--HGRAPVEV 296
Cdd:PRK10337 297 SRLDSLDNLQDVAEIPLEDLLQSAVMdiyHTAQQAGIDVRLTLNAHPVIRTgqpllLSLLVRNLLDNAIRysPQGSVVDV 376
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2225590578 297 TVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLR 368
Cdd:PRK10337 377 TLNARNFTVRDNGPGVTPEALARIGERFYRPPGQEATGSGLGLSIVRRIAKLHGMNVSFGNAPEGGFEAKVS 448
|
|
| PRK10604 |
PRK10604 |
sensor protein RstB; Provisional |
122-370 |
7.28e-19 |
|
sensor protein RstB; Provisional
Pssm-ID: 236724 [Multi-domain] Cd Length: 433 Bit Score: 87.35 E-value: 7.28e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 122 PH-RRLQKVARTARRIESGDLTARTGEsrgdDEITAIS---ATVDSMADSLHQRLLTEQRFTADVAHELRTPLMGL---V 194
Cdd:PRK10604 159 PHwQDMLKLEAAAQRLGDGHLAERIHF----DEGSSLErlgVAFNQMADNINALIASKKQLIDGIAHELRTPLVRLryrL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 195 TASELLPEGEATELVRDrVRVLRTLVEDLLEISRLDAGGERAESRRVPLAEAVSESLA--RTGQQTRF----TAADALCA 268
Cdd:PRK10604 235 EMSDNLSAAESQALNRD-IGQLEALIEELLTYARLDRPQNELHLSEPDLPAWLSTHLAdiQAVTPEKTvrldTPHQGDYG 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 269 ETDPRRLDRIVTNLVVNAHRHG----RAPVEVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLTI 341
Cdd:PRK10604 314 ALDMRLMERVLDNLLNNALRYAhsrvRVSLLLDGNQACLIVEDDGPGIPPEERERVFEPFVRLDPSRDRatgGCGLGLAI 393
|
250 260
....*....|....*....|....*....
gi 2225590578 342 ALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK10604 394 VHSIALAMGGSVNCDESELGGARFSFSWP 422
|
|
| NtrY |
COG5000 |
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ... |
169-370 |
1.45e-15 |
|
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];
Pssm-ID: 444024 [Multi-domain] Cd Length: 422 Bit Score: 77.31 E-value: 1.45e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 169 HQRLLTEQRFTADVAHELRTPLMGLVTASELL--------PEG-----EATELVRDRVRVLRTLVEDLLEISRLDAgger 235
Cdd:COG5000 195 AERLAAWGELARRIAHEIKNPLTPIQLSAERLrrkladklEEDredleRALDTIIRQVDRLKRIVDEFLDFARLPE---- 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 236 AESRRVPLAEAVSESL-----ARTGQQTRFT---AADALCAETDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVR- 306
Cdd:COG5000 271 PQLEPVDLNELLREVLalyepALKEKDIRLEldlDPDLPEVLADRDQLEQVLINLLKNAIEAIEEGGEIEVSTRREDGRv 350
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 307 -----DHGPGFPPELLndgpQR-----FRTgapeRGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG5000 351 rievsDNGPGIPEEVL----ERifepfFTT----KPKGTGLGLAIVKKIVEEHGGTIELESRPGGGTTFTIRLP 416
|
|
| COG4191 |
COG4191 |
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal ... |
70-370 |
2.78e-15 |
|
Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms];
Pssm-ID: 443345 [Multi-domain] Cd Length: 361 Bit Score: 76.38 E-value: 2.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 70 WAARTYRGEPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGESR 149
Cdd:COG4191 25 LLLLLLLLLALLLLLLALLLALLALLLLLLLLLLLLLLELLLLLLALLGGLLRLLLLLGLLLLLLLEALLLLLLAALDAE 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 150 GDDEITAISATVDSMADSLHQRLLTEQRF------------TADVAHELRTPLMGLVTASELLPEGEATELVRDRVRVL- 216
Cdd:COG4191 105 ENAELEELERDITELERAEEELRELQEQLvqseklaalgelAAGIAHEINNPLAAILGNAELLRRRLEDEPDPEELREAl 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 217 ----------RTLVEDLLEISRLDaggeRAESRRVPLAEAVSESLARTGQQTRFT--------AADALCAETDPRRLDRI 278
Cdd:COG4191 185 erilegaeraAEIVRSLRAFSRRD----EEEREPVDLNELIDEALELLRPRLKARgieveldlPPDLPPVLGDPGQLEQV 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 279 VTNLVVNAhRH----GRAPVEVTVAGTTVTV-----RDHGPGFPPELLndgpQR-----FRTGAPerGRGHGLGLTIALG 344
Cdd:COG4191 261 LLNLLINA-IDameeGEGGRITISTRREGDYvvisvRDNGPGIPPEVL----ERifepfFTTKPV--GKGTGLGLSISYG 333
|
330 340
....*....|....*....|....*.
gi 2225590578 345 QAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG4191 334 IVEKHGGRIEVESEPGGGTTFTITLP 359
|
|
| PRK11100 |
PRK11100 |
sensory histidine kinase CreC; Provisional |
98-370 |
1.40e-14 |
|
sensory histidine kinase CreC; Provisional
Pssm-ID: 236846 [Multi-domain] Cd Length: 475 Bit Score: 74.88 E-value: 1.40e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 98 RHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIesgdltaRTGES-----RGDDEITAISATVDSMADSLHQRL 172
Cdd:PRK11100 182 RRILWAGALLLGIALLIGAGVVWWLNRSIRRLTRYADAV-------TEGKPvplpkLGSSELRELAQALESMRVKLEGKA 254
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 173 LTEQrFTADVAHELRTPLMGLVTASELLPEGEATElvrDRVRV----------LRTLVEDLLEISRLDAGGERAESRRVP 242
Cdd:PRK11100 255 YVEQ-YVQTLTHELKSPLAAIRGAAELLQEDPPPE---DRARFtgniltqsarLQQLIDRLLELARLEQRQELEVLEPVA 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 243 LA-------EAVSESLARTGQQTRFTAADALcAETDPRRLDRIVTNLVVNA----HRHG--RAPVEVTVAGTTVTVRDHG 309
Cdd:PRK11100 331 LAalleelvEAREAQAAAKGITLRLRPDDAR-VLGDPFLLRQALGNLLDNAidfsPEGGtiTLSAEVDGEQVALSVEDQG 409
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2225590578 310 PGFPPELLNDGPQRFRTGA-PERGR-GHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK11100 410 PGIPDYALPRIFERFYSLPrPANGRkSTGLGLAFVREVARLHGGEVTLRNRPEGGVLATLTLP 472
|
|
| HATPase_c |
pfam02518 |
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ... |
270-370 |
1.73e-14 |
|
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain] Cd Length: 109 Bit Score: 68.93 E-value: 1.73e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 270 TDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIALG 344
Cdd:pfam02518 1 GDELRLRQVLSNLLDNALKHAAKAGEITVTLSEGGEltltvEDNGIGIPPEDLPRIFEPFSTADKRGGGGTGLGLSIVRK 80
|
90 100
....*....|....*....|....*.
gi 2225590578 345 QAEVIGASLSFANASDGGAVATLRLP 370
Cdd:pfam02518 81 LVELLGGTITVESEPGGGTTVTLTLP 106
|
|
| COG4251 |
COG4251 |
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal ... |
69-342 |
5.08e-14 |
|
Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms];
Pssm-ID: 443393 [Multi-domain] Cd Length: 503 Bit Score: 73.28 E-value: 5.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 69 MWAARTYRGEPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGES 148
Cdd:COG4251 169 ALLLAALAELELLLLLLLVLLLLLLLLLLLLLLLLRLLLELLLLLEAELLLSLGGGLGLLLLLLLLLVLLLLLILLLLLL 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 149 RGDDEITAISATVDSMADSLHQRL--LTE-----QRFTADVAHELRTPLMGLVTASELL---------PEG-EATELVRD 211
Cdd:COG4251 249 ILVLELLELRLELEELEEELEERTaeLERsneelEQFAYVASHDLREPLRKISGFSQLLeedygdkldEEGrEYLERIRD 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 212 RVRVLRTLVEDLLEISRLDAGGERAEsrRVPLAEAVSESLAR-----TGQQTRFTAADALCAETDPRRLDRIVTNLVVNA 286
Cdd:COG4251 329 AAERMQALIDDLLAYSRVGRQELEFE--PVDLNELLEEVLEDlepriEERGAEIEVGPLPTVRGDPTLLRQVFQNLISNA 406
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2225590578 287 ---HRHGRAPV-----EVTVAGTTVTVRDHGPGFPPELLND--GP-QRFRTGapERGRGHGLGLTIA 342
Cdd:COG4251 407 ikySRPGEPPRieigaEREGGEWVFSVRDNGIGIDPEYAEKifEIfQRLHSR--DEYEGTGIGLAIV 471
|
|
| PRK10755 |
PRK10755 |
two-component system sensor histidine kinase PmrB; |
110-373 |
6.42e-14 |
|
two-component system sensor histidine kinase PmrB;
Pssm-ID: 236751 [Multi-domain] Cd Length: 356 Bit Score: 71.92 E-value: 6.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 110 VIVPLSVLAAELphrrlqkVARTARRIESGDLTARTgesrgdDEITAISATVDSMADSLHQRLLTEQRFTADVAHELRTP 189
Cdd:PRK10755 85 ITRPLAELQKEL-------EARTADNLTPIAIHSST------LEIEAVTSALNQLVSRLTSTLDQERLFTADVAHELRTP 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 190 LMGLVTASELLPEG---EATELVrDRVRVLRTLVEDLLEISRLD---AGG-----ERAESRRVPLAEAVSESLARTGQQT 258
Cdd:PRK10755 152 LAGIRLHLELLEKQhhiDVAPLI-ARLDQMMHTVEQLLQLARAGqsfSSGhyqtvKLLEDVILPSQDELSEMLEQRQQTL 230
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 259 RFT-AADALCAETDPRRLDRIVTNLVVNAHRHgrAPV--------EVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTgAP 329
Cdd:PRK10755 231 LLPeSAADITVQGDATLLRLLLRNLVENAHRY--SPEgstitiklSQEDGGAVLAVEDEGPGIDESKCGELSKAFVR-MD 307
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 2225590578 330 ERGRGHGLGLTIALGQAEVIGASLSFANASD-GGAVATLRLPGDD 373
Cdd:PRK10755 308 SRYGGIGLGLSIVSRITQLHHGQFFLQNRQErSGTRAWVWLPKAQ 352
|
|
| HATPase_c |
smart00387 |
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases. |
270-370 |
1.14e-13 |
|
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain] Cd Length: 111 Bit Score: 66.52 E-value: 1.14e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 270 TDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPER--GRGHGLGLTI 341
Cdd:smart00387 1 GDPDRLRQVLSNLLDNAIKYTPEGGRITVTLERDGDhveitvEDNGPGIPPEDLEKIFEPFFRTDKRSrkIGGTGLGLSI 80
|
90 100
....*....|....*....|....*....
gi 2225590578 342 ALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:smart00387 81 VKKLVELHGGEISVESEPGGGTTFTITLP 109
|
|
| PRK10549 |
PRK10549 |
two-component system sensor histidine kinase BaeS; |
61-370 |
2.46e-12 |
|
two-component system sensor histidine kinase BaeS;
Pssm-ID: 182539 [Multi-domain] Cd Length: 466 Bit Score: 67.74 E-value: 2.46e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 61 PGPGDHPSMWAARTYRGEPVAVKIDMTADLLTRRA---LDRHMWKYS--------LLALAVIVPLS--VLAaelPHRRLq 127
Cdd:PRK10549 120 RGPIPPDGTRRPILVNGAEVGWVIASPVERLTRNTdinFDKQQRRTSwlivalstLLAALATFLLArgLLA---PVKRL- 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 128 kVARTaRRIESGDLTARTgESRGDDEITAISATVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASELLPEG---- 203
Cdd:PRK10549 196 -VEGT-HKLAAGDFTTRV-TPTSRDELGRLAQDFNQLASTLEKNEQMRRDFMADISHELRTPLAVLRGELEAIQDGvrkf 272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 204 --EATELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPLAEAVSESLARTGQQTRFTAADALCAET----DPRR 274
Cdd:PRK10549 273 tpESVASLQAEVGTLTKLVDDLHQLSLSDEGAlayRKTPVDLVPLLEVAGGAFRERFASRGLTLQLSLPDSAtvfgDPDR 352
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 275 LDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVR------DHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLTIALGQ 345
Cdd:PRK10549 353 LMQLFNNLLENSLRYTDSGGSLHISAEQRDKTlrltfaDSAPGVSDEQLQKLFERFYRTEGSRNRasgGSGLGLAICLNI 432
|
330 340
....*....|....*....|....*
gi 2225590578 346 AEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK10549 433 VEAHNGRIIAAHSPFGGVSITVELP 457
|
|
| PRK11466 |
PRK11466 |
hybrid sensory histidine kinase TorS; Provisional |
178-370 |
2.88e-12 |
|
hybrid sensory histidine kinase TorS; Provisional
Pssm-ID: 236914 [Multi-domain] Cd Length: 914 Bit Score: 68.01 E-value: 2.88e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 178 FTADVAHELRTPLMGLVTASELLPEGEATELVRDRVRV-------LRTLVEDLLEISRLDAGGERAESRRVPLA-EAVSE 249
Cdd:PRK11466 447 FLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAitdsgesLLTILNDILDYSAIEAGGKNVSVSDEPFEpRPLLE 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 250 SLARTGQ---QTRFTAADALCAET-------DPRRLDRIVTNLVVNAHR-----HGRAPVEVTVAGTTVTVRDHGPGFPP 314
Cdd:PRK11466 527 STLQLMSgrvKGRPIRLATDIADDlptalmgDPRRIRQVITNLLSNALRftdegSIVLRSRTDGEQWLVEVEDSGCGIDP 606
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 315 ELLNDGPQRFRTGAPERGrGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK11466 607 AKLAEIFQPFVQVSGKRG-GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLP 661
|
|
| phoR_proteo |
TIGR02966 |
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory ... |
178-341 |
5.28e-12 |
|
phosphate regulon sensor kinase PhoR; Members of this protein family are the regulatory histidine kinase PhoR associated with the phosphate ABC transporter in most Proteobacteria. Related proteins from Gram-positive organisms are not included in this model. The phoR gene usually is adjacent to the response regulator phoB gene (TIGR02154). [Signal transduction, Two-component systems]
Pssm-ID: 274368 [Multi-domain] Cd Length: 333 Bit Score: 66.08 E-value: 5.28e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 178 FTADVAHELRTPLMGLVTASELLPEG---------EATELVRDRVRVLRTLVEDLLEISRLDAGGERAESRRVPLAEAVS 248
Cdd:TIGR02966 117 FVANVSHELRTPLTVLRGYLETLADGpdedpeewnRALEIMLEQSQRMQSLVEDLLTLSRLESAASPLEDEPVDMPALLD 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 249 ------ESLA-RTGQQTRFTAADALCAETDPRRLDRIVTNLVVNAHRHGRAPV------EVTVAGTTVTVRDHGPGFPPE 315
Cdd:TIGR02966 197 hlrdeaEALSqGKNHQITFEIDGGVDVLGDEDELRSAFSNLVSNAIKYTPEGGtitvrwRRDGGGAEFSVTDTGIGIAPE 276
|
170 180
....*....|....*....|....*....
gi 2225590578 316 LLNDGPQRFRTGAPERGR---GHGLGLTI 341
Cdd:TIGR02966 277 HLPRLTERFYRVDKSRSRdtgGTGLGLAI 305
|
|
| HisKA |
pfam00512 |
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine ... |
176-232 |
1.09e-11 |
|
His Kinase A (phospho-acceptor) domain; dimerization and phospho-acceptor domain of histidine kinases.
Pssm-ID: 459839 [Multi-domain] Cd Length: 66 Bit Score: 59.53 E-value: 1.09e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 176 QRFTADVAHELRTPLMGLVTASELLPEG-------EATELVRDRVRVLRTLVEDLLEISRLDAG 232
Cdd:pfam00512 3 SEFLANLSHELRTPLTAIRGYLELLRDEkldeeqrEYLETILRSAERLLRLINDLLDLSRIEAG 66
|
|
| HisKA |
smart00388 |
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine ... |
176-232 |
2.51e-11 |
|
His Kinase A (phosphoacceptor) domain; Dimerisation and phosphoacceptor domain of histidine kinases.
Pssm-ID: 214644 [Multi-domain] Cd Length: 66 Bit Score: 58.73 E-value: 2.51e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 176 QRFTADVAHELRTPLMGLVTASELL-------PEGEATELVRDRVRVLRTLVEDLLEISRLDAG 232
Cdd:smart00388 3 REFLANLSHELRTPLTAIRGYLELLldtelseEQREYLETILREAERLLRLINDLLDLSRIEAG 66
|
|
| HATPase_TutC-TodS-like |
cd16925 |
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas ... |
271-370 |
6.68e-11 |
|
Histidine kinase-like ATPase domain of hybrid sensor histidine kinases similar to Pseudomonas putida TodS and Thauera aromatica TutC; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component hybrid sensor histidine kinase (HKs) such Pseudomonas putida TodS HK of the TodS-TodT two-component regulatory system (TCS) which controls the expression of a toluene degradation pathway. Thauera aromatica TutC may be part of a TCS that is involved in anaerobic toluene metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), PAS sensor domain(s) and a REC domain.
Pssm-ID: 340402 [Multi-domain] Cd Length: 110 Bit Score: 59.04 E-value: 6.68e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 271 DPRRLDRIVTNLVVNAHRH----GRAP---VEVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLT 340
Cdd:cd16925 1 DAEKYERVVLNLLSNAFKFtpdgGRIRcilEKFRLNRFLLTVSDSGPGIPPNLREEIFERFRQGDGSSTRahgGTGLGLS 80
|
90 100 110
....*....|....*....|....*....|
gi 2225590578 341 IALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16925 81 IVKEFVELHGGTVTVSDAPGGGALFQVELP 110
|
|
| envZ |
PRK09467 |
osmolarity sensor protein; Provisional |
108-370 |
8.42e-11 |
|
osmolarity sensor protein; Provisional
Pssm-ID: 236531 [Multi-domain] Cd Length: 435 Bit Score: 63.01 E-value: 8.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 108 LAVIVPLSVLAAEL-------PHRRLQKVARTARRiesGDLTARTGESrGDDEITAISATVDSMADSLHQrlLTEQR--F 178
Cdd:PRK09467 159 TLAIGLLSVAGGWLfiriqnrPLVALEHAALQVGK---GEIPPPLREY-GASEVRSVTRAFNQMAAGIKQ--LEDDRtlL 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 179 TADVAHELRTPLMGLVTASELLPEGE---ATELVRDrvrvlrtlVEDLLEI-------SRLDAGGERaesRRVPLAEAVS 248
Cdd:PRK09467 233 MAGVSHDLRTPLTRIRLATEMMSEEDgylAESINKD--------IEECNAIieqfidyLRTGQEMPM---EMADLNALLG 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 249 ESL-ARTGQQTRFTAADALCAETDPRR---LDRIVTNLVVNAHRHG----RAPVEVTVAGTTVTVRDHGPGFPPELLNDG 320
Cdd:PRK09467 302 EVIaAESGYEREIETALQPGPIEVPMNpiaIKRALANLVVNAARYGngwiKVSSGTEGKRAWFQVEDDGPGIPPEQLKHL 381
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 321 PQRFRTGAPERG-RGHGLGLTIAlgqAEVIGA---SLSFANASDGGAVATLRLP 370
Cdd:PRK09467 382 FQPFTRGDSARGsSGTGLGLAIV---KRIVDQhngKVELGNSEEGGLSARAWLP 432
|
|
| NtrB |
COG3852 |
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms]; |
168-370 |
1.59e-10 |
|
Signal transduction histidine kinase NtrB, nitrogen specific [Signal transduction mechanisms];
Pssm-ID: 443061 [Multi-domain] Cd Length: 361 Bit Score: 61.79 E-value: 1.59e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 168 LHQRLLTEQRFTADVAHELRTPLMGLVTASELL-------PEGEATELVRDRVRVLRTLVEDLLEISRldagGERAESRR 240
Cdd:COG3852 128 RAEKLAAVGELAAGLAHEIRNPLTGIRGAAQLLerelpddELREYTQLIIEEADRLNNLVDRLLSFSR----PRPPEREP 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 241 VPLAEAVSESL----ARTGQQTRFT---AADALCAETDPRRLDRIVTNLVVNA----HRHGR-------APVEVTVAGTT 302
Cdd:COG3852 204 VNLHEVLERVLellrAEAPKNIRIVrdyDPSLPEVLGDPDQLIQVLLNLVRNAaeamPEGGTitirtrvERQVTLGGLRP 283
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2225590578 303 VTV-----RDHGPGFPPELLNdgpqR----FRTGapeRGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG3852 284 RLYvrievIDNGPGIPEEILD----RifepFFTT---KEKGTGLGLAIVQKIVEQHGGTIEVESEPGKGTTFRIYLP 353
|
|
| cpxA |
PRK09470 |
envelope stress sensor histidine kinase CpxA; |
122-228 |
7.85e-10 |
|
envelope stress sensor histidine kinase CpxA;
Pssm-ID: 236532 [Multi-domain] Cd Length: 461 Bit Score: 59.95 E-value: 7.85e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 122 PHRRLQkvaRTARRIESGDLTARTGESRGDDEITAISATVDSMADSLHQRLLTEQRFTADVAHELRTPLMGLVTASELL- 200
Cdd:PRK09470 193 PARKLK---NAADEVAQGNLRQHPELETGPQEFRQAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLATALLr 269
|
90 100 110
....*....|....*....|....*....|....
gi 2225590578 201 -PEGEATELVR-----DRvrvLRTLVEDLLEISR 228
Cdd:PRK09470 270 rRQGESKELERieteaQR---LDSMINDLLVLSR 300
|
|
| HisKA |
cd00082 |
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed ... |
176-228 |
1.09e-09 |
|
Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via trans-autophosphorylation by the catalytic domain of the histidine kinase. They subsequently transfer the phosphoryl group to the Asp acceptor residue of a response regulator protein. Two-component signalling systems, consisting of a histidine protein kinase that senses a signal input and a response regulator that mediates the output, are ancient and evolutionarily conserved signaling mechanisms in prokaryotes and eukaryotes.
Pssm-ID: 119399 [Multi-domain] Cd Length: 65 Bit Score: 54.14 E-value: 1.09e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2225590578 176 QRFTADVAHELRTPLMGLVTASELLPEG--------EATELVRDRVRVLRTLVEDLLEISR 228
Cdd:cd00082 5 GEFLANVSHELRTPLTAIRGALELLEEEllddeeqrEYLERIREEAERLLRLINDLLDLSR 65
|
|
| ActS_PrrB_HisK |
NF033792 |
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, ... |
163-370 |
3.00e-09 |
|
ActS/PrrB/RegB family redox-sensitive histidine kinase; This redox-responsive histidine kinase, found in alpha-proteobacteria, shows strong sequence conservation, including the notable motif [VA]AAAAHELGTPxTI. It always acts as a partner to an ActR/PrrA/RegA family global response regulator transcription factor in a two-component sensory transduction system. Lineage-specific names and gene symbols given to this histidine kinase reflect downstream regulator changes such as entry into stationary phase, anaerobic expression of photosynthesis genes, and survival of exposure to low pH.
Pssm-ID: 468186 [Multi-domain] Cd Length: 423 Bit Score: 58.30 E-value: 3.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 163 SMADSL---HQRLLTEQRFT------ADVAHELRTPLMGL-VTASELLPEGEATELVRDRVRVLRTLVEDLLEI-SRLDA 231
Cdd:NF033792 181 RLSDALaatELVLAREQHLSaldglaAAAAHELGTPLATIaLVAKELERELPDDPPLREDAELLRSQAERCRDIlRRLTS 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 232 GGERAES--RRVPLAEAVSESLA--RT-GQQTRFTAADALCAETDPRRLDRIV---TNLVVN----AHRHGRAPVEVTVA 299
Cdd:NF033792 261 LGEEGDAhlDRLPLSALIEEAAAphRGfGKEIEVVVAGDPGEEPVIRRNPEILyglGNLIENavdfARSTVTVTASWDAE 340
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 300 GTTVTVRDHGPGFPPELLNdgpqrfRTGAP-----------ERGRGHGLGLTIALGQAEVIGASLSFANASD--GGAVAT 366
Cdd:NF033792 341 SVTITIEDDGPGFPPDVLS------RIGEPyvttrrgeerrPGGGGLGLGLFIAKTLLERSGATVTFANRPPpeGGAVVT 414
|
....
gi 2225590578 367 LRLP 370
Cdd:NF033792 415 VRWP 418
|
|
| AdeS_HK |
NF012226 |
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component ... |
106-370 |
9.84e-09 |
|
two-component sensor histidine kinase AdeS; Mutations in this component of the two-component regulatory system for the AdeABC efflux pump can confer adaptive resistance to certain antibiotics, including tigecycline.
Pssm-ID: 411090 [Multi-domain] Cd Length: 353 Bit Score: 56.16 E-value: 9.84e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 106 LALAVIVPLSVLAaelphrrlqkvaRTARRIESGDLTARTGESRGDD-EITAISATVDSMADSLHQRLLTEQRFTADVAH 184
Cdd:NF012226 80 LAQRFIVPINFLA------------DAAKKISQGDLSARAEDSQIHSaEISELMHNFNDMAQKLESSVKNAQVWNAAIAH 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 185 ELRTP-------LMGLV----TASELLPEGeatelVRDRVRVLRTLVEDLLEISRLDAGGERAESRRVPLAEAVSESL-- 251
Cdd:NF012226 148 ELRTPitilqgrLQGILdgvfEPDPALFKS-----LLNQVEGLSHLVEDLRTLSLVENQQLRLNYESVDLKDSIEKVLkm 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 252 -------ARTGQQTRFTAADALCaetDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFPPELLND 319
Cdd:NF012226 223 fedrleqAQLTIVLNLTATPVFC---DRRRIEQVLIALIDNAIRYANAGKLKISSSVIQDDwilqiEDEGPGIAEEYQQD 299
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 320 GPQRFRTGAPERGR---GHGLGLtiALGQAEVIG--ASLSFANaSDGGAVATLRLP 370
Cdd:NF012226 300 LFNPFFRLEQSRNKefgGTGLGL--AVVHAIVIAhkGSIEYSN-SQGNSVFTIKLP 352
|
|
| PRK15347 |
PRK15347 |
two component system sensor kinase; |
180-370 |
9.88e-09 |
|
two component system sensor kinase;
Pssm-ID: 237951 [Multi-domain] Cd Length: 921 Bit Score: 56.96 E-value: 9.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 180 ADVAHELRTPLMGLVTASELLPEGEAT-------ELVRDRVRVLRTLVEDLLEISRLDAGG---ERAESRRVPLAE---- 245
Cdd:PRK15347 403 TTISHEIRTPLNGVLGALELLQNTPLTaeqmdlaDTARQCTLSLLAIINNLLDFSRIESGQmtlSLEETALLPLLDqaml 482
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 246 -----AVSESLA-RTgqqtrFTAAD-ALCAETDPRRLDRIVTNLVVNAHR---HGRAPVEVTVAGTTVTVR--DHGPGFP 313
Cdd:PRK15347 483 tiqgpAQSKSLTlRT-----FVGAHvPLYLHLDSLRLRQILVNLLGNAVKfteTGGIRLRVKRHEQQLCFTveDTGCGID 557
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2225590578 314 PELLNDGPQRFRTgAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK15347 558 IQQQQQIFTPFYQ-ADTHSQGTGLGLTIASSLAKMMGGELTLFSTPGVGSCFSLVLP 613
|
|
| PRK09835 |
PRK09835 |
Cu(+)/Ag(+) sensor histidine kinase; |
102-341 |
1.19e-08 |
|
Cu(+)/Ag(+) sensor histidine kinase;
Pssm-ID: 182101 [Multi-domain] Cd Length: 482 Bit Score: 56.32 E-value: 1.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 102 KYSLLALAVIVPLSV-----LAAELPHRRLQKVARTARRIESGDLTARTGESRGDDEITAISATVDSMADSLHQRLLTEQ 176
Cdd:PRK09835 184 KNKLIMTASVISLLIvfivlLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQS 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 177 RFTADVAHELRTPLMGLVTASELLPEGEATELVRDRV---------RVLRtLVEDLLEISRLDAGGERAESRRVPLAEAV 247
Cdd:PRK09835 264 NFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVlysnleeltRMAK-MVSDMLFLAQADNNQLIPEKKMLDLADEV 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 248 S------ESLARTGQQTRFTAADALCAETDPRRLDRIVTNLVVNAHRHgrAPVEVTVAGTTVTVRD------HGPGFP-- 313
Cdd:PRK09835 343 GkvfdffEAWAEERGVELRFVGDPCQVAGDPLMLRRAISNLLSNALRY--TPAGEAITVRCQEVDHqvqlvvENPGTPia 420
|
250 260 270
....*....|....*....|....*....|.
gi 2225590578 314 PELLNDGPQRFRTGAPER---GRGHGLGLTI 341
Cdd:PRK09835 421 PEHLPRLFDRFYRVDPSRqrkGEGSGIGLAI 451
|
|
| HATPase_EnvZ-like |
cd16950 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
275-370 |
8.43e-08 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli EnvZ and Pseudomonas aeruginosa BfmS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Escherichia coli EnvZ of the EnvZ-OmpR two-component regulatory system (TCS), which functions in osmoregulation. It also contains the HATPase domain of Pseudomonas aeruginosa BfmS, the HK of the BfmSR TCS, which functions in the regulation of the rhl quorum-sensing system and bacterial virulence in P. aeruginosa. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also contain a periplasmic domain.
Pssm-ID: 340426 [Multi-domain] Cd Length: 101 Bit Score: 49.75 E-value: 8.43e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 275 LDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVR----DHGPGFPPELLNDGPQRFRTGAPERG-RGHGLGLTIALGQAEVI 349
Cdd:cd16950 1 LKRVLSNLVDNALRYGGGWVEVSSDGEGNRTRiqvlDNGPGIAPEEVDELFQPFYRGDNARGtSGTGLGLAIVQRISDAH 80
|
90 100
....*....|....*....|.
gi 2225590578 350 GASLSFANASDGGAVATLRLP 370
Cdd:cd16950 81 GGSLTLANRAGGGLCARIELP 101
|
|
| phoR |
PRK11006 |
phosphate regulon sensor histidine kinase PhoR; |
178-341 |
1.00e-06 |
|
phosphate regulon sensor histidine kinase PhoR;
Pssm-ID: 182895 [Multi-domain] Cd Length: 430 Bit Score: 50.39 E-value: 1.00e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 178 FTADVAHELRTPLMGLVTASELLPE--------GEATELVRDRVRVLRTLVEDLLEISRLDAGG--ERAESRRVPLA--- 244
Cdd:PRK11006 207 FFANVSHELRTPLTVLQGYLEMMQDqplegalrEKALHTMREQTQRMEGLVKQLLTLSKIEAAPtiDLNEKVDVPMMlrv 286
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 245 -EAVSESLARTGQQTRFTAADALCAETDPRRLDRIVTNLVVNAHRHGRAPVE------VTVAGTTVTVRDHGPGFPPELL 317
Cdd:PRK11006 287 lEREAQTLSQGKHTITFEVDNSLKVFGNEDQLRSAISNLVYNAVNHTPEGTHitvrwqRVPQGAEFSVEDNGPGIAPEHI 366
|
170 180
....*....|....*....|....*..
gi 2225590578 318 NDGPQRFRTGAPERGR---GHGLGLTI 341
Cdd:PRK11006 367 PRLTERFYRVDKARSRqtgGSGLGLAI 393
|
|
| HAMP |
cd06225 |
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ... |
124-168 |
2.15e-06 |
|
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.
Pssm-ID: 381743 [Multi-domain] Cd Length: 45 Bit Score: 43.97 E-value: 2.15e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 2225590578 124 RRLQKVARTARRIESGDLTARTgESRGDDEITAISATVDSMADSL 168
Cdd:cd06225 2 RPLRRLTEAARRIAEGDLDVRV-PVRSKDEIGELARAFNQMAERL 45
|
|
| HATPase_BaeS-like |
cd16946 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
271-370 |
2.51e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BaeS HK of the BaeS/BaeR two-component regulatory system (TCS), which responds to envelope stress. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensory domain.
Pssm-ID: 340422 [Multi-domain] Cd Length: 109 Bit Score: 45.92 E-value: 2.51e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 271 DPRRLDRIVTNLVVNAHRHG------RAPVEVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLTI 341
Cdd:cd16946 1 DRDRLQQLFVNLLENSLRYTdtggklRIRAAQTPQEVRLDVEDSAPGVSDDQLARLFERFYRVESSRNRasgGSGLGLAI 80
|
90 100
....*....|....*....|....*....
gi 2225590578 342 ALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16946 81 CHNIALAHGGTISAEHSPLGGLRLVLTLP 109
|
|
| HATPase_BasS-like |
cd16940 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
271-369 |
2.70e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli BasS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) similar to Escherichia coli BasS HK of the BasS-BasR two-component regulatory system (TCS). Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some contain a HAMP sensory domain, while some an N-terminal two-component sensor kinase domain.
Pssm-ID: 340417 [Multi-domain] Cd Length: 113 Bit Score: 45.86 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 271 DPRRLDRIVTNLVVNAHRHGRAPVE-----VTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIALGQ 345
Cdd:cd16940 10 DALLLFLLLRNLVDNAVRYSPQGSRveiklSADDGAVIRVEDNGPGIDEEELEALFERFYRSDGQNYGGSGLGLSIVKRI 89
|
90 100
....*....|....*....|....
gi 2225590578 346 AEVIGASLSFANASDGGAVATLRL 369
Cdd:cd16940 90 VELHGGQIFLGNAQGGGLEAWVRL 113
|
|
| PRK11360 |
PRK11360 |
two-component system sensor histidine kinase AtoS; |
164-370 |
3.07e-06 |
|
two-component system sensor histidine kinase AtoS;
Pssm-ID: 236901 [Multi-domain] Cd Length: 607 Bit Score: 49.20 E-value: 3.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 164 MADSLHQ--RLLTEQRFTADVAHELRTPLMG-------LVTASELLPEGEATELVRDRVRVLRTLVEDLLEISRldagGE 234
Cdd:PRK11360 377 LQRRVARqeRLAALGELVAGVAHEIRNPLTAirgyvqiWRQQTSDPPSQEYLSVVLREVDRLNKVIDQLLEFSR----PR 452
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 235 RAESRRVPLAEAVSESL---ARTGQQTRFTAADALCAE-----TDPRRLDRIVTNLVVNA----HRHGR---APVEVTVA 299
Cdd:PRK11360 453 ESQWQPVSLNALVEEVLqlfQTAGVQARVDFETELDNElppiwADPELLKQVLLNILINAvqaiSARGKiriRTWQYSDG 532
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2225590578 300 GTTVTVRDHGPGFPPELLndgPQRFRTGAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK11360 533 QVAVSIEDNGCGIDPELL---KKIFDPFFTTKAKGTGLGLALSQRIINAHGGDIEVESEPGVGTTFTLYLP 600
|
|
| PRK10364 |
PRK10364 |
two-component system sensor histidine kinase ZraS; |
180-370 |
3.48e-06 |
|
two-component system sensor histidine kinase ZraS;
Pssm-ID: 236674 [Multi-domain] Cd Length: 457 Bit Score: 48.63 E-value: 3.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 180 ADVAHELRTPL---MGLVT--ASELLPEGEATELVR------DRvrvLRTLVEDLLEISRldagGERAESRRVPLAEAVS 248
Cdd:PRK10364 242 AGVAHEIRNPLssiKGLAKyfAERAPAGGEAHQLAQvmakeaDR---LNRVVSELLELVK----PTHLALQAVDLNDLIN 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 249 ESLARTGQ-------QTRFTAADAL-CAETDPRRLDRIVTNLVVNA----HRHGR--APVEVTVAGTTVTVRDHGPGFPP 314
Cdd:PRK10364 315 HSLQLVSQdansreiQLRFTANDTLpEIQADPDRLTQVLLNLYLNAiqaiGQHGVisVTASESGAGVKISVTDSGKGIAA 394
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 315 ELLndgPQRFRTGAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK10364 395 DQL---EAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLP 447
|
|
| PRK10490 |
PRK10490 |
sensor protein KdpD; Provisional |
158-370 |
3.90e-06 |
|
sensor protein KdpD; Provisional
Pssm-ID: 236701 [Multi-domain] Cd Length: 895 Bit Score: 48.88 E-value: 3.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 158 SATVDSMADSLHQRLLteqrftADVAHELRTPLMGLVTASELL-----PEG-----EATELvrdRVRVLRT--LVEDLLE 225
Cdd:PRK10490 653 QARLASEREQLRNALL------AALSHDLRTPLTVLFGQAEILtldlaSEGspharQASEI---RQQVLNTtrLVNNLLD 723
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 226 ISRLDAGGERAESRRVPLAEAVSESLAR-----TGQQTRFT-AADALCAETDPRRLDRIVTNLVVNAHR--HGRAPVEVT 297
Cdd:PRK10490 724 MARIQSGGFNLRKEWLTLEEVVGSALQMlepglSGHPINLSlPEPLTLIHVDGPLFERVLINLLENAVKyaGAQAEIGID 803
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2225590578 298 VAGTTVTVR----DHGPGFPPELLNDGPQRFRTGAPERG-RGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK10490 804 AHVEGERLQldvwDNGPGIPPGQEQLIFDKFARGNKESAiPGVGLGLAICRAIVEVHGGTIWAENRPEGGACFRVTLP 881
|
|
| HATPase_HupT_MifS-like |
cd16976 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
306-369 |
4.22e-06 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhodobacter capsulatus HupT and Pseudomonas aeruginosa MifS; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Rhodobacter capsulatus HupT of the HupT-HupR two-component regulatory system (TCS), which regulates the synthesis of HupSL, a membrane bound [NiFe]hydrogenase. It also contains the HATPase domain of Pseudomonas aeruginosa MifS, the HK of the MifS-MifR TCS, which may be involved in sensing alpha-ketoglutarate and regulating its transport and subsequent metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some also have a C-terminal PAS sensor domain.
Pssm-ID: 340435 [Multi-domain] Cd Length: 102 Bit Score: 45.14 E-value: 4.22e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 306 RDHGPGFPPELLNDGPQRFRTGAPErGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRL 369
Cdd:cd16976 40 RDNGPGIAEEHLSRVFDPFFTTKPV-GKGTGLGLSISYGIVEEHGGRLSVANEEGAGARFTFDL 102
|
|
| HAMP |
smart00304 |
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; |
124-172 |
1.22e-05 |
|
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
Pssm-ID: 197640 [Multi-domain] Cd Length: 53 Bit Score: 42.24 E-value: 1.22e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 2225590578 124 RRLQKVARTARRIESGDLTARTgESRGDDEITAISATVDSMADSLHQRL 172
Cdd:smart00304 5 RPLRRLAEAAQRIADGDLTVRL-PVDGRDEIGELARAFNEMADRLEETI 52
|
|
| HK_WalK |
NF033092 |
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in ... |
169-286 |
1.47e-05 |
|
cell wall metabolism sensor histidine kinase WalK; This model describes WalK as found in Staphylococcus aureus (sp|Q2G2U4.1|WALK_STAA8). A shorter version, as found in Streptococcus pneumoniae, called WalK(Spn) or VicK, is not included. WalK is part of a two-component system and works with partner protein WalR.
Pssm-ID: 467964 [Multi-domain] Cd Length: 594 Bit Score: 47.05 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 169 HQRLLTEQR-FTADVAHELRTPLMGLVTASELLPEG--EATELVRDRVRVLRT-------LVEDLLEISRLDAGGERAES 238
Cdd:NF033092 365 QEKIEQERReFVANVSHELRTPLTTMRSYLEALADGawKDPELAPRFLGVTQNetermirLVNDLLQLSRMDSKDYKLNK 444
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 239 RRVPLAEAVSESLAR----TGQQ----TRFTAADALCAETDPRRLDRIVTNLVVNA 286
Cdd:NF033092 445 EWVNFNEFFNYIIDRfemiLKNKnitfKREFPKRDLWVEIDTDKITQVLDNIISNA 500
|
|
| Tar |
COG0840 |
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms]; |
69-170 |
2.16e-05 |
|
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
Pssm-ID: 440602 [Multi-domain] Cd Length: 533 Bit Score: 46.17 E-value: 2.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 69 MWAARTYRGEPVAVKIDMTADLLTRRALDRHMWKYSLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTgES 148
Cdd:COG0840 153 LAAAAAAAAALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRI-DV 231
|
90 100
....*....|....*....|..
gi 2225590578 149 RGDDEITAISATVDSMADSLHQ 170
Cdd:COG0840 232 DSKDEIGQLADAFNRMIENLRE 253
|
|
| HAMP |
pfam00672 |
HAMP domain; |
124-170 |
2.36e-05 |
|
HAMP domain;
Pssm-ID: 459898 [Multi-domain] Cd Length: 53 Bit Score: 41.46 E-value: 2.36e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 2225590578 124 RRLQKVARTARRIESGDLTARTGESRGdDEITAISATVDSMADSLHQ 170
Cdd:pfam00672 8 RPLRRLAEAARRIASGDLDVRLPVSGR-DEIGELARAFNQMAERLRE 53
|
|
| COG4192 |
COG4192 |
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal ... |
102-370 |
2.50e-05 |
|
Signal transduction histidine kinase regulating phosphoglycerate transport system [Signal transduction mechanisms];
Pssm-ID: 443346 [Multi-domain] Cd Length: 640 Bit Score: 46.22 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 102 KYSLLALAVIVPLSVLAAEL-------PH--RRLQKVARTARRIESGDLTARTGESrGDDEITAISATV----DSMADSL 168
Cdd:COG4192 322 QQSGILLLAIALLSLLLAVLinyfyvrRRlvKRLNALSDAMAAIAAGDLDVPIPVD-GNDEIGRIARLLrvfrDQAIEKT 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 169 HQrLLTE----------------------------QRFTAdVAHELRTPL----MGLVTASELLpEGEATELVRDRVRVL 216
Cdd:COG4192 401 QE-LETEieerkrieknlrqtqdeliqaakmavvgQTMTS-LAHELNQPLnamsMYLFSAKKAL-EQENYAQLPTSLDKI 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 217 RTLVEDLLEISRldagGERAESRR-------VPLAEAVS------ESLARTgQQTRFTAADALCAETDPRRLDRIVTNLV 283
Cdd:COG4192 478 EGLIERMDKIIK----SLRQFSRKsdtplqpVDLRQVIEqawelvESRAKP-QQITLHIPDDLMVQGDQVLLEQVLVNLL 552
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 284 VNA------HRHGRAPVEVTVAGTTVTVRDHGPGFP--PELLndgpQRFRTgapERGRGHGLGLTIALGQAEVIGASLSF 355
Cdd:COG4192 553 VNAldavatQPQISVDLLSNAENLRVAISDNGNGWPlvDKLF----TPFTT---TKEVGLGLGLSICRSIMQQFGGDLYL 625
|
330
....*....|....*
gi 2225590578 356 ANASDGGAVATLRLP 370
Cdd:COG4192 626 ASTLERGAMVILEFN 640
|
|
| HATPase_TmoS-FixL-DctS-like |
cd16920 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
307-370 |
1.60e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Rhizobium meliloti FixL, and Rhodobacter capsulatus DctS; includes hybrid sensor histidine kinase similar to Pseudomonas mendocina TmoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs), such as Pseudomonas mendocina TmoS HK of the TmoS-TmoT TCS, which controls the expression of the toluene-4-monooxygenase pathway, Rhizobium meliloti FixL HK of the FixL-FixJ TCS, which regulates the expression of the genes related to nitrogen fixation in the root nodule in response to O(2) levels, and Rhodobacter capsulatus DctS of the DctS-DctR TCS, which controls synthesis of the high-affinity C4-dicarboxylate transport system. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and PAS sensor domain(s); many are hybrid sensor histidine kinases as they also contain a REC signal receiver domain.
Pssm-ID: 340397 [Multi-domain] Cd Length: 104 Bit Score: 40.46 E-value: 1.60e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 307 DHGPGFPPELLNDGPQRFRTGAPErgrGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16920 44 DTGPGIAEEVAGQLFDPFYTTKSE---GLGMGLSICRSIIEAHGGRLSVESPAGGGATFQFTLP 104
|
|
| HATPase_AtoS-like |
cd16943 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
272-370 |
2.09e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 AtoS; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Escherichia coli AtoS, an HK of the AtoS-AtoC TCS. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA); some have accessory domains such as HAMP or PAS sensor domains or CBS-pair domains.
Pssm-ID: 340419 [Multi-domain] Cd Length: 105 Bit Score: 40.10 E-value: 2.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 272 PRRLDRIVTNLVVNA----HRHGR--APVEVTVAGTTVTVRDHGPGFPPELLNDGPQRFRTGAPErGRGHGLGLTIALGQ 345
Cdd:cd16943 1 PSQLNQVLLNLLVNAaqamEGRGRitIRTWAHVDQVLIEVEDTGSGIDPEILGRIFDPFFTTKPV-GEGTGLGLSLSYRI 79
|
90 100
....*....|....*....|....*
gi 2225590578 346 AEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16943 80 IQKHGGTIRVASVPGGGTRFTIILP 104
|
|
| YesM |
COG2972 |
Sensor histidine kinase YesM [Signal transduction mechanisms]; |
104-370 |
2.54e-04 |
|
Sensor histidine kinase YesM [Signal transduction mechanisms];
Pssm-ID: 442211 [Multi-domain] Cd Length: 445 Bit Score: 42.70 E-value: 2.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 104 SLLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTarTGESRGDDEITAISATVDSMADSLHQRLLTEQRFTADVA 183
Cdd:COG2972 163 ILLLLLLALLLSYLLSRSITRPIKRLKKAMKKVEKGDLV--RLEVSGNDEIGILARSFNEMVERIKELIEEVYELELEKK 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 184 H-ELR-------------TplmgLVTASELLPEGEATELVRdrvrvlrtLVEDLLEISR--LDAGGERaesrrVPLAEAV 247
Cdd:COG2972 241 EaELKalqaqinphflfnT----LNSIRWLAELEDPEEAEE--------MLEALSKLLRysLSKGDEL-----VTLEEEL 303
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 248 SesLAR---TGQQTRF--------TAADALCAETDPRRldrIVTNLVVNAHRHGRAPVEVTVAGTTVTVRDH-------- 308
Cdd:COG2972 304 E--LIKsylEIQKLRFgdrleveiEIDEELLDLLIPKL---ILQPLVENAIEHGIEPKEGGGTIRISIRKEGdrlvitve 378
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2225590578 309 --GPGFPPELLndgpQRFRTGAPERGRGHGLGLT-----IALgqAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG2972 379 dnGVGMPEEKL----EKLLEELSSKGEGRGIGLRnvrerLKL--YYGEEYGLEIESEPGEGTTVTIRIP 441
|
|
| marine_sort_HK |
TIGR03785 |
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is ... |
104-249 |
2.82e-04 |
|
proteobacterial dedicated sortase system histidine kinase; This histidine kinase protein is paired with an adjacent response regulator (TIGR03787) gene. It co-occurs with a variant sortase enzyme (TIGR03784), usually in the same gene neighborhood, in proteobacterial species most of which are marine, and with an LPXTG motif-containing sortase target conserved protein (TIGR03788). Sortases and LPXTG proteins are far more common in Gram-positive bacteria, where sortase systems mediate attachment to the cell wall or cross-linking of pilin structures. We give this predicted sensor histidine kinase the gene symbol psdS, for Proteobacterial Dedicated Sortase system Sensor histidine kinase.
Pssm-ID: 163497 [Multi-domain] Cd Length: 703 Bit Score: 42.81 E-value: 2.82e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 104 SLLALAVIVPLSVLAAELphRRLQKVARTArrIES-GDLTARTGESRGDDEITAISATVDSMADSLHQRLLTEQRFTADV 182
Cdd:TIGR03785 417 SIGTLALFGFASWISWRI--RRLSDDAEAA--IDSqGRISGAIPASRSRDEIGDLSRSFAQMVARLRQYTHYLENMSSRL 492
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 183 AHELRTPLMGLVTASELLPEGEATELVR---DRVRV----LRTLVEDLLEISRLDAGGERAESRRVPLAEAVSE 249
Cdd:TIGR03785 493 SHELRTPVAVVRSSLENLELQALEQEKQkylERAREgterLSMILNNMSEATRLEQAIQSAEVEDFDLSEVLSG 566
|
|
| ComP |
COG4585 |
Signal transduction histidine kinase ComP [Signal transduction mechanisms]; |
105-370 |
2.92e-04 |
|
Signal transduction histidine kinase ComP [Signal transduction mechanisms];
Pssm-ID: 443642 [Multi-domain] Cd Length: 252 Bit Score: 41.91 E-value: 2.92e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 105 LLALAVIVPLSVLAAELPHRRLQKVARTARRIESGDLTARTGESRgddEITAISATVDSMADSLHQRLLteQRFTAdVAH 184
Cdd:COG4585 1 LLALALLGALALLVGALLGLLLALVLLRARRAERAAELERELAAR---AEEAREEERRRIARELHDGVG--QSLSA-IKL 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 185 ELRTPLMGLVTASELLPE--GEATELVRDRVRVLRTLVEDLLEISRLDAGGERAesrrvpLAEAVSESLARTGQQTRFTA 262
Cdd:COG4585 75 QLEAARRLLDADPEAAREelEEIRELAREALAELRRLVRGLRPPALDDLGLAAA------LEELAERLLRAAGIRVELDV 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 263 ADALCAETDPRRLD--RIVTNLVVNAHRHGRAPVEVTVAGTTVTV-----RDHGPGFPpellndgpqrfrtgaPERGRGH 335
Cdd:COG4585 149 DGDPDRLPPEVELAlyRIVQEALTNALKHAGATRVTVTLEVDDGEltltvRDDGVGFD---------------PEAAPGG 213
|
250 260 270
....*....|....*....|....*....|....*
gi 2225590578 336 GLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG4585 214 GLGLRGMRERAEALGGTLTIGSAPGGGTRVRATLP 248
|
|
| PRK09959 |
PRK09959 |
acid-sensing system histidine kinase EvgS; |
173-370 |
4.06e-04 |
|
acid-sensing system histidine kinase EvgS;
Pssm-ID: 182169 [Multi-domain] Cd Length: 1197 Bit Score: 42.41 E-value: 4.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 173 LTEQRFTADVAHELRTPLMGLVTASELLPEG--------EATELVRDRVRVLRTLVEDLLEISRLDAGGERAESRRVPL- 243
Cdd:PRK09959 710 VAKSQFLATMSHEIRTPISSIMGFLELLSGSglskeqrvEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIp 789
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 244 -----------AEAVSESLARTGQQtrfTAADALCAETDPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVRDH---- 308
Cdd:PRK09959 790 tlvqntchsfgAIAASKSIALSCSS---TFPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLGHIDDNHavik 866
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2225590578 309 ------GPGFPPELLNDGPQRF-RTGAPERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:PRK09959 867 mtimdsGSGLSQEEQQQLFKRYsQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIP 935
|
|
| HATPase_NtrY-like |
cd16944 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
307-370 |
4.13e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Azorhizobium caulinodans NtrY; This family includes the histidine kinase-like ATPase (HATPase) domains of various histidine kinases (HKs) of two-component signal transduction systems (TCSs) such as Azorhizobium caulinodans ORS571 NtrY of the NtrY-NtrX TCS, which is involved in nitrogen fixation and metabolism. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA) and a HAMP sensor domain; some also have PAS sensor domains.
Pssm-ID: 340420 [Multi-domain] Cd Length: 108 Bit Score: 39.44 E-value: 4.13e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2225590578 307 DHGPGFPPELLNDGPQRFRTgapERGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16944 48 DNGKGFPREMRHRATEPYVT---TRPKGTGLGLAIVKKIMEEHGGRISLSNREAGGACIRIILP 108
|
|
| HATPase_SpaK_NisK-like |
cd16975 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
271-368 |
5.44e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK; This family includes histidine kinase-like ATPase (HATPase) domain of two-component sensor histidine kinases similar to Bacillus subtilis SpaK and Lactococcus lactis NisK. SpaK is the histidine kinase (HK) of the SpaK-SpaR two-component regulatory system (TCS), which is involved in the regulation of the biosynthesis of lantibiotic subtilin. NisK is the HK of the NisK-NisR TCS, which is involved in the regulation of the biosynthesis of lantibiotic nisin. SpaK and NisK may function as membrane-associated protein kinases that phosphorylate SpaR and NisR, respectively, in response to environmental signals.
Pssm-ID: 340434 [Multi-domain] Cd Length: 107 Bit Score: 38.98 E-value: 5.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 271 DPRRLDRIVTNLVVNAHRHGRAPVEVTVAGTTVTV------RDHGPGFPPELLNDGPQRFRTGAPERGRG--HGLGLTIA 342
Cdd:cd16975 1 DTLLLSRALINIISNACQYAPEGGTVSISIYDEEEylyfeiWDNGHGFSEQDLKKALELFYRDDTSRRSGghYGMGLYIA 80
|
90 100
....*....|....*....|....*.
gi 2225590578 343 LGQAEVIGASLSFANASDGGAVATLR 368
Cdd:cd16975 81 KNLVEKHGGSLIIENSQKGGAEVTVK 106
|
|
| HATPase_DpiB-CitA-like |
cd16915 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
306-370 |
5.45e-04 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Escherichia coli K-12 DpiB, DcuS, and Bacillus subtilis CitS, DctS, and YufL; This family includes histidine kinase-like ATPase domains of Escherichia coli K-12 DpiB and DcuS, and Bacillus subtilis CitS, DctS and MalK histidine kinases (HKs) all of which are two component transduction systems (TCSs). E. coli K-12 DpiB (also known as CitA) is the histidine kinase (HK) of DpiA-DpiB, a two-component signal transduction system (TCS) required for the expression of citrate-specific fermentation genes and genes involved in plasmid inheritance. E. coli K-12 DcuS (also known as YjdH) is the HK of DcuS-DcuR, a TCS that in the presence of the extracellular C4-dicarboxlates, activates the expression of the genes of anaerobic fumarate respiration and of aerobic C4-dicarboxylate uptake. CitS is the HK of Bacillus subtilis CitS-CitT, a TCS which regulates expression of CitM, the Mg-citrate transporter. Bacillus subtilis DctS forms a tripartite sensor unit (DctS/DctA/DctB) for sensing C4 dicarboxylates. Bacillus subtilis MalK (also known as YfuL) is the HK of MalK-MalR (YufL-YufM) a TCS which regulates the expression of the malate transporters MaeN (YufR) and YflS, and is essential for utilization of malate in minimal medium. Proteins having this DpiB-CitA-like HATPase domain generally have sensor domains such as Cache and PAS, and a histidine kinase A (HisKA)-like SpoOB-type, alpha-helical domain.
Pssm-ID: 340392 [Multi-domain] Cd Length: 104 Bit Score: 38.81 E-value: 5.45e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2225590578 306 RDHGPGFPPELLNDGPQRFRTGAPERGRGHGLGLTIAlgQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:cd16915 42 RDTGPGIAPELRDKVFERGVSTKGQGERGIGLALVRQ--SVERLGGSITVESEPGGGTTFSIRIP 104
|
|
| PRK09303 |
PRK09303 |
histidine kinase; |
166-286 |
1.49e-03 |
|
histidine kinase;
Pssm-ID: 236462 [Multi-domain] Cd Length: 380 Bit Score: 40.32 E-value: 1.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 166 DSLHQRLLTEQRFTADVAHELRTPLMGLVTASE---LLPEGEATEL-----------VRDRVRVLRTLVEDLLEISRLDA 231
Cdd:PRK09303 142 ETLLEQLKFKDRVLAMLAHDLRTPLTAASLALEtleLGQIDEDTELkpalieqlqdqARRQLEEIERLITDLLEVGRTRW 221
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2225590578 232 GGERAESRRVPL----AEAVSESLAR-TGQQTRFTA---ADALCAETDPRRLDRIVTNLVVNA 286
Cdd:PRK09303 222 EALRFNPQKLDLgslcQEVILELEKRwLAKSLEIQTdipSDLPSVYADQERIRQVLLNLLDNA 284
|
|
| HATPase_RstB-like |
cd16939 |
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to ... |
275-370 |
1.51e-03 |
|
Histidine kinase-like ATPase domain of two-component sensor histidine kinases similar to Salmonella typhimurium RstB; This family includes the histidine kinase-like ATPase (HATPase) domains of various two-component sensor histidine kinase (HKs) such as Salmonella typhimurium RstB HK of the RstA-RstB two-component regulatory system (TCS), which regulates expression of the constituents participating in pyrimidine metabolism and iron acquisition, and may be required for regulation of Salmonella motility and invasion. Proteins having this HATPase domain also contain a histidine kinase dimerization and phosphoacceptor domain (HisKA), and a HAMP sensor domain.
Pssm-ID: 340416 [Multi-domain] Cd Length: 104 Bit Score: 37.79 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2225590578 275 LDRIVTNLVVNAHRHGRAPVEVTVAGTTVTVR----DHGPGFPPELLNDGPQRFRTGAPERGR---GHGLGLTIALGQAE 347
Cdd:cd16939 1 MARALDNLLRNALRYAHRTVRIALLVSGGRLTliveDDGPGIPAAARERVFEPFVRLDPSRDRatgGFGLGLAIVHRVAL 80
|
90 100
....*....|....*....|...
gi 2225590578 348 VIGASLSFANASDGGAVATLRLP 370
Cdd:cd16939 81 WHGGHVECDDSELGGACFRLTWP 103
|
|
| ABC_6TM_exporter_like |
cd18564 |
Six-transmembrane helical domain (TMD) of an uncharacterized ABC exporter, and similar ... |
101-148 |
3.92e-03 |
|
Six-transmembrane helical domain (TMD) of an uncharacterized ABC exporter, and similar proteins; This group includes a subunit of six transmembrane (TM) helices typically found in the ATP-binding cassette (ABC) transporters that function as exporters, which contain 6 TM helices per subunit (domain), or a total of 12 TM helices for the complete transporter. The ABC exporters are found in both prokaryotes and eukaryotes, where they mediate the cellular secretion of toxic compounds and a various type of lipids. ABC transporters typically consist of two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs). The sequences and structures of the TMDs are quite varied between the different type of transporters, suggesting the chemical diversity of the translocated substrates, while NBDs are conserved among all ABC transporters. The two NBDs together bind and hydrolyze ATP, thereby providing the driving force for transport, while the TMDs participate in substrate recognition and translocation across the lipid membrane. However, some ABC genes are organized as half-transporters, which must form either homodimers or heterodimers to form a functional transporter. The ABC exporters play a role in multidrug resistance to antibiotics and anticancer agents, and mutations in these proteins have been shown to cause severe human diseases such as cystic fibrosis.
Pssm-ID: 350008 [Multi-domain] Cd Length: 307 Bit Score: 38.65 E-value: 3.92e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 2225590578 101 WKYSLLALAViVPLSVLAAELPHRRLQKVARTARRIEsGDLTARTGES 148
Cdd:cd18564 154 WQLALIALAV-APLLLLAARRFSRRIKEASREQRRRE-GALASVAQES 199
|
|
| CitA |
COG3290 |
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction ... |
306-370 |
6.67e-03 |
|
Sensor histidine kinase DipB regulating citrate/malate metabolism [Signal transduction mechanisms];
Pssm-ID: 442519 [Multi-domain] Cd Length: 389 Bit Score: 38.29 E-value: 6.67e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2225590578 306 RDHGPGFPPELLNdgpQRFRTGAPE-RGRGHGLGLTIALGQAEVIGASLSFANASDGGAVATLRLP 370
Cdd:COG3290 323 EDSGPGIPEELLE---KIFERGFSTkLGEGRGLGLALVKQIVEKYGGTIEVESEEGEGTVFTVRLP 385
|
|
| |
