NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2204356482|ref|WP_240533049|]
View 

DUF1275 family protein [Escherichia coli]

Protein Classification

YoaK family protein( domain architecture ID 1446)

YoaK family protein is a DUF1275 domain-containing protein, similar to Bacillus subtilis transmembrane protein YoaK

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF1275 super family cl01453
Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial ...
 9-111 5.65e-17

Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.


The actual alignment was detected with superfamily member COG3619:

Pssm-ID: 470207  Cd Length: 228  Bit Score: 73.42  E-value: 5.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2204356482   9 PDGLTTLVTGMTGVMGMGVRNATSRLLLSITSPSTMMTGNVTQLTIDIINYF---QIPSTENHTKLIKSGSSVIGFLAGA 85
Cdd:COG3619   113 GLSLPDLLAVLLLAFAMGLQNATFTKISGAVVRTTHVTGNLTDLGIELGRLLrgkRREARADRRKLLLYLLLILAFLLGA 192

                          90       100
                  ....*....|....*....|....*.
gi 2204356482  86 GLGTLGYILMGFFSVLIPVIMIVAVI 111
Cdd:COG3619   193 VLGALLFLRLGFAALLLPAALLLALA 218
 
Name Accession Description Interval E-value
YoaK COG3619
Uncharacterized membrane protein YoaK, UPF0700 family [Function unknown];
9-111 5.65e-17

Uncharacterized membrane protein YoaK, UPF0700 family [Function unknown];


Pssm-ID: 442837  Cd Length: 228  Bit Score: 73.42  E-value: 5.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2204356482   9 PDGLTTLVTGMTGVMGMGVRNATSRLLLSITSPSTMMTGNVTQLTIDIINYF---QIPSTENHTKLIKSGSSVIGFLAGA 85
Cdd:COG3619   113 GLSLPDLLAVLLLAFAMGLQNATFTKISGAVVRTTHVTGNLTDLGIELGRLLrgkRREARADRRKLLLYLLLILAFLLGA 192

                          90       100
                  ....*....|....*....|....*.
gi 2204356482  86 GLGTLGYILMGFFSVLIPVIMIVAVI 111
Cdd:COG3619   193 VLGALLFLRLGFAALLLPAALLLALA 218
DUF1275 pfam06912
Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial ...
 10-111 1.95e-11

Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.


Pssm-ID: 462038  Cd Length: 202  Bit Score: 58.01  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2204356482  10 DGLTTLVTGMTGVMGMGVRNATSRLLLSITSPSTMMTGNVTQLTIDIINYFQIPSTENHTKLIKSGSSVIGFLAGAGLGT 89
Cdd:pfam06912  99 GVAPNLLAIALLAFAMGLQNATFRRLSGAEIATTVLTGNLTDLGIDLADKLGLALKKALAKRNRRLAIILAFLLGAVLGA 178

                          90       100
                  ....*....|....*....|..
gi 2204356482  90 LGYILMGFFSVLIPVIMIVAVI 111
Cdd:pfam06912 179 LLYKRLGAGALWVAAALLLILA 200
 
Name Accession Description Interval E-value
YoaK COG3619
Uncharacterized membrane protein YoaK, UPF0700 family [Function unknown];
9-111 5.65e-17

Uncharacterized membrane protein YoaK, UPF0700 family [Function unknown];


Pssm-ID: 442837  Cd Length: 228  Bit Score: 73.42  E-value: 5.65e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2204356482   9 PDGLTTLVTGMTGVMGMGVRNATSRLLLSITSPSTMMTGNVTQLTIDIINYF---QIPSTENHTKLIKSGSSVIGFLAGA 85
Cdd:COG3619   113 GLSLPDLLAVLLLAFAMGLQNATFTKISGAVVRTTHVTGNLTDLGIELGRLLrgkRREARADRRKLLLYLLLILAFLLGA 192

                          90       100
                  ....*....|....*....|....*.
gi 2204356482  86 GLGTLGYILMGFFSVLIPVIMIVAVI 111
Cdd:COG3619   193 VLGALLFLRLGFAALLLPAALLLALA 218
DUF1275 pfam06912
Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial ...
 10-111 1.95e-11

Protein of unknown function (DUF1275); This family consists of several hypothetical bacterial proteins of around 200 residues in length. The function of this family is unknown although most members have 6 TM regions, and may be putative permeases.


Pssm-ID: 462038  Cd Length: 202  Bit Score: 58.01  E-value: 1.95e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2204356482  10 DGLTTLVTGMTGVMGMGVRNATSRLLLSITSPSTMMTGNVTQLTIDIINYFQIPSTENHTKLIKSGSSVIGFLAGAGLGT 89
Cdd:pfam06912  99 GVAPNLLAIALLAFAMGLQNATFRRLSGAEIATTVLTGNLTDLGIDLADKLGLALKKALAKRNRRLAIILAFLLGAVLGA 178

                          90       100
                  ....*....|....*....|..
gi 2204356482  90 LGYILMGFFSVLIPVIMIVAVI 111
Cdd:pfam06912 179 LLYKRLGAGALWVAAALLLILA 200
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH