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Conserved domains on  [gi|2185786480|ref|WP_236689960|]
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hypothetical protein [Cronobacter muytjensii]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tox-HNH-HHH super family cl21429
HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH ...
 38-137 1.56e-37

HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with characteriztic conserved s[GD]xxR and HHH motifs. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion system.


The actual alignment was detected with superfamily member pfam15637:

Pssm-ID: 434827  Cd Length: 103  Bit Score: 123.34  E-value: 1.56e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2185786480  38 PAYSIDTTTFNSGTPT--SKGGIRNNKEFWQQWSELQPDSLSKNNLYRIqELGLSPKIDDTWIKVFPEHVNYKGDTLIHH 115
Cdd:pfam15637   1 PRLEVDMRYVGKGKSGsnSAGWLRNSKYFWKEMLKSNPEYFSKKNRQLI-RAGQSPIVDKAWIKEFPQHAGYSNDTLVHH 79

                          90       100
                  ....*....|....*....|..
gi 2185786480 116 HVDFGPYAIPVPGKTHVGSGGV 137
Cdd:pfam15637  80 HIGQGGQAVPIPASLHPGSGGV 101
 
Name Accession Description Interval E-value
Tox-HNH-HHH pfam15637
HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH ...
 38-137 1.56e-37

HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with characteriztic conserved s[GD]xxR and HHH motifs. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion system.


Pssm-ID: 434827  Cd Length: 103  Bit Score: 123.34  E-value: 1.56e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2185786480  38 PAYSIDTTTFNSGTPT--SKGGIRNNKEFWQQWSELQPDSLSKNNLYRIqELGLSPKIDDTWIKVFPEHVNYKGDTLIHH 115
Cdd:pfam15637   1 PRLEVDMRYVGKGKSGsnSAGWLRNSKYFWKEMLKSNPEYFSKKNRQLI-RAGQSPIVDKAWIKEFPQHAGYSNDTLVHH 79

                          90       100
                  ....*....|....*....|..
gi 2185786480 116 HVDFGPYAIPVPGKTHVGSGGV 137
Cdd:pfam15637  80 HIGQGGQAVPIPASLHPGSGGV 101
 
Name Accession Description Interval E-value
Tox-HNH-HHH pfam15637
HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH ...
 38-137 1.56e-37

HNH/Endo VII superfamily nuclease toxin with a HHH motif; A predicted toxin of the HNH/Endonuclease VII fold present in bacterial polymorphic toxin systems with characteriztic conserved s[GD]xxR and HHH motifs. In bacterial polymorphic toxin systems, the toxin is exported by the type 2, type 5, type 6, type 7 or Photorhabdus virulence cassette (PVC)-type secretion system.


Pssm-ID: 434827  Cd Length: 103  Bit Score: 123.34  E-value: 1.56e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2185786480  38 PAYSIDTTTFNSGTPT--SKGGIRNNKEFWQQWSELQPDSLSKNNLYRIqELGLSPKIDDTWIKVFPEHVNYKGDTLIHH 115
Cdd:pfam15637   1 PRLEVDMRYVGKGKSGsnSAGWLRNSKYFWKEMLKSNPEYFSKKNRQLI-RAGQSPIVDKAWIKEFPQHAGYSNDTLVHH 79

                          90       100
                  ....*....|....*....|..
gi 2185786480 116 HVDFGPYAIPVPGKTHVGSGGV 137
Cdd:pfam15637  80 HIGQGGQAVPIPASLHPGSGGV 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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