|
Name |
Accession |
Description |
Interval |
E-value |
| MenH |
COG0596 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ... |
6-269 |
3.04e-45 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis
Pssm-ID: 440361 [Multi-domain] Cd Length: 221 Bit Score: 151.69 E-value: 3.04e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 6 IDGKALHYSDQG-TGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGfPEGTRNLDDLTRHALALLDHLN 84
Cdd:COG0596 9 VDGVRLHYREAGpDGPPVVLLHGLPGSSYEWRPLIPALAAGYRVIAPDLRGHGRSDK-PAGGYTLDDLADDLAALLDALG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 85 IERCSIVGLSVGGMWGAIAALLAPERITGLVLMDtylgketeatkayyfslinkleetgafpaPLLDIVVPIFFRPGIDP 164
Cdd:COG0596 88 LERVVLVGHSMGGMVALELAARHPERVAGLVLVD-----------------------------EVLAALAEPLRRPGLAP 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 165 QSpLYQAFRAALAGMNAEQLRQTIAPlgrmifgrddrlglieqlnadtTLVMCGDADIPRPPEETREMAGLI-GCPYVLV 243
Cdd:COG0596 139 EA-LAALLRALARTDLRERLARITVP----------------------TLVIWGEKDPIVPPALARRLAELLpNAELVVL 195
|
250 260
....*....|....*....|....*.
gi 2184988178 244 PEAGHIANLENPDFVSGALMTFLARV 269
Cdd:COG0596 196 PGAGHFPPLEQPEAFAAALRDFLARL 221
|
|
| protocat_pcaD |
TIGR02427 |
3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that ... |
11-267 |
3.67e-38 |
|
3-oxoadipate enol-lactonase; Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other]
Pssm-ID: 131480 [Multi-domain] Cd Length: 251 Bit Score: 134.41 E-value: 3.67e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 11 LHYSDQGTG---PVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDgFPEGTRNLDDLTRHALALLDHLNIER 87
Cdd:TIGR02427 2 LHYRLDGAAdgaPVLVFINSLGTDLRMWDPVLPALTPDFRVLRYDKRGHGLSD-APEGPYSIEDLADDVLALLDHLGIER 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 88 CSIVGLSVGGMWGAIAALLAPERITGLVLMDT---YLGKETEATKayyfslINKLEETGAfpAPLLDIVVPIFFRPGI-D 163
Cdd:TIGR02427 81 AVFCGLSLGGLIAQGLAARRPDRVRALVLSNTaakIGTPESWNAR------IAAVRAEGL--AALADAVLERWFTPGFrE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 164 PQSPLYQAFRAALAGMNAEQLRQTIAPLGRMIFgrDDRLGLIeqlnADTTLVMCGDADIPRPPEETREMAGLI-GCPYVL 242
Cdd:TIGR02427 153 AHPARLDLYRNMLVRQPPDGYAGCCAAIRDADF--RDRLGAI----AVPTLCIAGDQDGSTPPELVREIADLVpGARFAE 226
|
250 260
....*....|....*....|....*
gi 2184988178 243 VPEAGHIANLENPDFVSGALMTFLA 267
Cdd:TIGR02427 227 IRGAGHIPCVEQPEAFNAALRDFLR 251
|
|
| Abhydrolase_1 |
pfam00561 |
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes. |
20-255 |
4.92e-18 |
|
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
Pssm-ID: 395444 [Multi-domain] Cd Length: 245 Bit Score: 81.01 E-value: 4.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 20 PVVLLGHSYLWDKGMWSAQLDTLA-SQYRVIVPDLWGHGESDGFPEGTR-NLDDLTRHALALLDHLNIERCSIVGLSVGG 97
Cdd:pfam00561 1 PPVLLLHGLPGSSDLWRKLAPALArDGFRVIALDLRGFGKSSRPKAQDDyRTDDLAEDLEYILEALGLEKVNLVGHSMGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 98 MWGAIAALLAPERITGLVLMDTyLGKETEATKAYYFSLINKLEETGAFPAPLL---------DIVVPIFFRpgIDPQSPL 168
Cdd:pfam00561 81 LIALAYAAKYPDRVKALVLLGA-LDPPHELDEADRFILALFPGFFDGFVADFApnplgrlvaKLLALLLLR--LRLLKAL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 169 YQAFRAALAGM-NAEQLRQTIAPLGRMIFGRDDRLGLIEQLNADtTLVMCGDADIPRPPEETREMAGLIGCPYVLV-PEA 246
Cdd:pfam00561 158 PLLNKRFPSGDyALAKSLVTGALLFIETWSTELRAKFLGRLDEP-TLIIWGDQDPLVPPQALEKLAQLFPNARLVViPDA 236
|
....*....
gi 2184988178 247 GHIANLENP 255
Cdd:pfam00561 237 GHFAFLEGP 245
|
|
| PRK14875 |
PRK14875 |
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional |
6-269 |
3.27e-16 |
|
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
Pssm-ID: 184875 [Multi-domain] Cd Length: 371 Bit Score: 77.29 E-value: 3.27e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 6 IDGKALHYSDQGTG---PVVLLgHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDgfPE-GTRNLDDLTRHALALLD 81
Cdd:PRK14875 116 IGGRTVRYLRLGEGdgtPVVLI-HGFGGDLNNWLFNHAALAAGRPVIALDLPGHGASS--KAvGAGSLDELAAAVLAFLD 192
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 82 HLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTY-LGKE----------TEATKAyyfSLINKLEETGAFPA--- 147
Cdd:PRK14875 193 ALGIERAHLVGHSMGGAVALRLAARAPQRVASLTLIAPAgLGPEingdyidgfvAAESRR---ELKPVLELLFADPAlvt 269
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 148 -PLLDIVVPIFFRPGI-DPQSPLyqAFRAALAGMNAEQLRQTIAPLG---RMIFGRDDRLglieqlnadttlvmcgdadI 222
Cdd:PRK14875 270 rQMVEDLLKYKRLDGVdDALRAL--ADALFAGGRQRVDLRDRLASLAipvLVIWGEQDRI-------------------I 328
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2184988178 223 PRPpeETREMAGLIGCpyVLVPEAGHIANLENPDFVSGALMTFLARV 269
Cdd:PRK14875 329 PAA--HAQGLPDGVAV--HVLPGAGHMPQMEAAADVNRLLAEFLGKA 371
|
|
| PldB |
COG2267 |
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism]; |
7-155 |
8.30e-14 |
|
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
Pssm-ID: 441868 [Multi-domain] Cd Length: 221 Bit Score: 68.88 E-value: 8.30e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 7 DGKALHY----SDQGTGPVVLLGHSYLWDKGMWSAQLDTLASQ-YRVIVPDLWGHGESDGFPEGTRNLDDLTRHALALLD 81
Cdd:COG2267 12 DGLRLRGrrwrPAGSPRGTVVLVHGLGEHSGRYAELAEALAAAgYAVLAFDLRGHGRSDGPRGHVDSFDDYVDDLRAALD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 82 HLNIE---RCSIVGLSVGGMWGAIAALLAPERITGLVLMDT-YLGKETEATKAYYFSLINKLEETGAFPAPLL------D 151
Cdd:COG2267 92 ALRARpglPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPaYRADPLLGPSARWLRALRLAEALARIDVPVLvlhggaD 171
|
....
gi 2184988178 152 IVVP 155
Cdd:COG2267 172 RVVP 175
|
|
| PRK03592 |
PRK03592 |
haloalkane dehalogenase; Provisional |
1-121 |
1.12e-11 |
|
haloalkane dehalogenase; Provisional
Pssm-ID: 235135 Cd Length: 295 Bit Score: 63.86 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 1 MPNLLIDGKALHYSDQGTGPVVLLGH-----SYLWDKGMwsaqlDTLASQYRVIVPDLWGHGESDGFPEGTRnLDDLTRH 75
Cdd:PRK03592 9 MRRVEVLGSRMAYIETGEGDPIVFLHgnptsSYLWRNII-----PHLAGLGRCLAPDLIGMGASDKPDIDYT-FADHARY 82
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 2184988178 76 ALALLDHLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTYL 121
Cdd:PRK03592 83 LDAWFDALGLDDVVLVGHDWGSALGFDWAARHPDRVRGIAFMEAIV 128
|
|
| DAP2 |
COG1506 |
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism]; |
7-268 |
2.04e-10 |
|
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
Pssm-ID: 441115 [Multi-domain] Cd Length: 234 Bit Score: 59.26 E-value: 2.04e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 7 DGKALHY-----SDQGTGPVVLLGHSYLWDK-GMWSAQLDTLASQ-YRVIVPDLWGHGESDGFPeGTRNLDDLTR--HAL 77
Cdd:COG1506 6 DGTTLPGwlylpADGKKYPVVVYVHGGPGSRdDSFLPLAQALASRgYAVLAPDYRGYGESAGDW-GGDEVDDVLAaiDYL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 78 ALLDHLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMdtylgketeatkAYYFSLINKLEETGAFPAPLLDivVPIF 157
Cdd:COG1506 85 AARPYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVAL------------AGVSDLRSYYGTTREYTERLMG--GPWE 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 158 FRPGIDPQSPLYqafraalagmNAEQLRqtiAPLgrmifgrddrlglieqlnadttLVMCGDADIPRPPEETREM---AG 234
Cdd:COG1506 151 DPEAYAARSPLA----------YADKLK---TPL----------------------LLIHGEADDRVPPEQAERLyeaLK 195
|
250 260 270
....*....|....*....|....*....|....*..
gi 2184988178 235 LIGCP--YVLVPEAGH-IANLENPDFVsGALMTFLAR 268
Cdd:COG1506 196 KAGKPveLLVYPGEGHgFSGAGAPDYL-ERILDFLDR 231
|
|
| YvaK |
COG1647 |
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism]; |
42-269 |
1.32e-09 |
|
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 441253 [Multi-domain] Cd Length: 246 Bit Score: 57.26 E-value: 1.32e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 42 LASQ-YRVIVPDLWGHGESDGFPEGTRnLDDLTRHALALLDHL--NIERCSIVGLSVGgmwGAIAALLAPER--ITGLVL 116
Cdd:COG1647 38 LAKAgYTVYAPRLPGHGTSPEDLLKTT-WEDWLEDVEEAYEILkaGYDKVIVIGLSMG---GLLALLLAARYpdVAGLVL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 117 MDTYLgketeatkayyfslinKLEETGAFPAPLLDIVVPIFFRPGIDPQSPLYQAFRAALAGMNAeqlrqtIAPLGRMIf 196
Cdd:COG1647 114 LSPAL----------------KIDDPSAPLLPLLKYLARSLRGIGSDIEDPEVAEYAYDRTPLRA------LAELQRLI- 170
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2184988178 197 grDDRLGLIEQLNADtTLVMCGDADIPRPPEETREMAGLIGCP---YVLVPEAGH-IANLENPDFVSGALMTFLARV 269
Cdd:COG1647 171 --REVRRDLPKITAP-TLIIQSRKDEVVPPESARYIYERLGSPdkeLVWLEDSGHvITLDKDREEVAEEILDFLERL 244
|
|
| PRK10673 |
PRK10673 |
esterase; |
42-144 |
2.21e-08 |
|
esterase;
Pssm-ID: 182637 [Multi-domain] Cd Length: 255 Bit Score: 53.58 E-value: 2.21e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 42 LASQYRVIVPDLWGHGESDGFPEgtRNLDDLTRHALALLDHLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTyl 121
Cdd:PRK10673 39 LVNDHDIIQVDMRNHGLSPRDPV--MNYPAMAQDLLDTLDALQIEKATFIGHSMGGKAVMALTALAPDRIDKLVAIDI-- 114
|
90 100 110
....*....|....*....|....*....|
gi 2184988178 122 gketeATKAYY-------FSLINKLEETGA 144
Cdd:PRK10673 115 -----APVDYHvrrhdeiFAAINAVSEAGA 139
|
|
| PRK03204 |
PRK03204 |
haloalkane dehalogenase; Provisional |
11-121 |
2.54e-08 |
|
haloalkane dehalogenase; Provisional
Pssm-ID: 179554 [Multi-domain] Cd Length: 286 Bit Score: 53.71 E-value: 2.54e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 11 LHYSDQGTGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGES---DGFpegTRNLDDLTRHALALLDHLNIER 87
Cdd:PRK03204 26 IHYIDEGTGPPILLCHGNPTWSFLYRDIIVALRDRFRCVAPDYLGFGLSerpSGF---GYQIDEHARVIGEFVDHLGLDR 102
|
90 100 110
....*....|....*....|....*....|....
gi 2184988178 88 CSIVGLSVGGMWGAIAALLAPERITGLVLMDTYL 121
Cdd:PRK03204 103 YLSMGQDWGGPISMAVAVERADRVRGVVLGNTWF 136
|
|
| PLN02824 |
PLN02824 |
hydrolase, alpha/beta fold family protein |
8-268 |
3.14e-08 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 178419 [Multi-domain] Cd Length: 294 Bit Score: 53.59 E-value: 3.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 8 GKALHYSDQGT-GPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESD-----GFPEGT-RNLDDLTRHALALL 80
Cdd:PLN02824 17 GYNIRYQRAGTsGPALVLVHGFGGNADHWRKNTPVLAKSHRVYAIDLLGYGYSDkpnprSAPPNSfYTFETWGEQLNDFC 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 81 DHLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTYLG----------------------KETEATKAYYFSLI-- 136
Cdd:PLN02824 97 SDVVGDPAFVICNSVGGVVGLQAAVDAPELVRGVMLINISLRglhikkqpwlgrpfikafqnllRETAVGKAFFKSVAtp 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 137 ----NKLEETGAFPAPLLDIVVPIFFRPGIDPQS-PLYQAFRAALAG-MNAEQLRQTIAPLgrmifgrddrlglieqlna 210
Cdd:PLN02824 177 etvkNILCQCYHDDSAVTDELVEAILRPGLEPGAvDVFLDFISYSGGpLPEELLPAVKCPV------------------- 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 2184988178 211 dttLVMCGDADIPRPPEETREMAGLIGC-PYVLVPEAGHIANLENPDFVSGALMTFLAR 268
Cdd:PLN02824 238 ---LIAWGEKDPWEPVELGRAYANFDAVeDFIVLPGVGHCPQDEAPELVNPLIESFVAR 293
|
|
| Abhydrolase_6 |
pfam12697 |
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ... |
42-258 |
2.32e-07 |
|
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.
Pssm-ID: 463673 [Multi-domain] Cd Length: 211 Bit Score: 50.16 E-value: 2.32e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 42 LASQYRVIVPDLWGHGESDGFPEGTRNLDDLTRHALALLDHLNIercSIVGLSVGGMwgaIAALLAPERITGLVLMDTYL 121
Cdd:pfam12697 18 LAAGVAVLAPDLPGHGSSSPPPLDLADLADLAALLDELGAARPV---VLVGHSLGGA---VALAAAAAALVVGVLVAPLA 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 122 GKETEAtkAYYFSLINKLEETGAFPAPLLDIVVPIFFrPGIDPQSPLYQAFRAALAGMNAEQLRQTIAPLGRMIfgrddr 201
Cdd:pfam12697 92 APPGLL--AALLALLARLGAALAAPAWLAAESLARGF-LDDLPADAEWAAALARLAALLAALALLPLAAWRDLP------ 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 2184988178 202 lglieqlnaDTTLVMCGDADIPrPPEETREMAGLIGCPYVLVPEAGHiANLENPDFV 258
Cdd:pfam12697 163 ---------VPVLVLAEEDRLV-PELAQRLLAALAGARLVVLPGAGH-LPLDDPEEV 208
|
|
| FrsA |
COG1073 |
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ... |
15-120 |
4.94e-07 |
|
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];
Pssm-ID: 440691 [Multi-domain] Cd Length: 253 Bit Score: 49.53 E-value: 4.94e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 15 DQGTGPVVLLGHSYLWDKGMWSAQLDTLASQ-YRVIVPDLWGHGESDGFPegtRNLDDLTRH-ALALLDHL----NIERC 88
Cdd:COG1073 33 ASKKYPAVVVAHGNGGVKEQRALYAQRLAELgFNVLAFDYRGYGESEGEP---REEGSPERRdARAAVDYLrtlpGVDPE 109
|
90 100 110
....*....|....*....|....*....|....*.
gi 2184988178 89 SIV--GLSvggMWGAIAALLAPE--RITGLVLMDTY 120
Cdd:COG1073 110 RIGllGIS---LGGGYALNAAATdpRVKAVILDSPF 142
|
|
| Hydrolase_4 |
pfam12146 |
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ... |
52-248 |
1.35e-06 |
|
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.
Pssm-ID: 463473 [Multi-domain] Cd Length: 238 Bit Score: 48.36 E-value: 1.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 52 DLWGHGESDGFPEGTRNLDDLTRHALALLDHL----NIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTYLGketea 127
Cdd:pfam12146 38 DHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIreehPGLPLFLLGHSMGGLIAALYALRYPDKVDGLILSAPALK----- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 128 TKAYYFSLINKLEetgafpAPLLDIVVP-IFFRPGIDPQSPL-YQAFRAALAgmnAEQLRQTIAPLGrmiFGRDDRLG-- 203
Cdd:pfam12146 113 IKPYLAPPILKLL------AKLLGKLFPrLRVPNNLLPDSLSrDPEVVAAYA---ADPLVHGGISAR---TLYELLDAge 180
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 2184988178 204 -LIEQLNADT--TLVMCGDADIPRPPEETREMAGLIGCP---YVLVPEAGH 248
Cdd:pfam12146 181 rLLRRAAAITvpLLLLHGGADRVVDPAGSREFYERAGSTdktLKLYPGLYH 231
|
|
| PRK00870 |
PRK00870 |
haloalkane dehalogenase; Provisional |
11-121 |
2.89e-06 |
|
haloalkane dehalogenase; Provisional
Pssm-ID: 179147 [Multi-domain] Cd Length: 302 Bit Score: 47.66 E-value: 2.89e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 11 LHYSDQGT--GPVVLLGH-----SYLWDKgMwsaqLDTLASQ-YRVIVPDLWGHGESDgfpEGTRnLDDLT--RHA---L 77
Cdd:PRK00870 36 MHYVDEGPadGPPVLLLHgepswSYLYRK-M----IPILAAAgHRVIAPDLIGFGRSD---KPTR-REDYTyaRHVewmR 106
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 2184988178 78 ALLDHLNIERCSIVGLSVGGMWGAIAALLAPERITGLVLMDTYL 121
Cdd:PRK00870 107 SWFEQLDLTDVTLVCQDWGGLIGLRLAAEHPDRFARLVVANTGL 150
|
|
| PLN02578 |
PLN02578 |
hydrolase |
8-119 |
3.43e-06 |
|
hydrolase
Pssm-ID: 215315 [Multi-domain] Cd Length: 354 Bit Score: 47.53 E-value: 3.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 8 GKALHYSDQGTGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESD-GFPEGTRNLddLTRHALALLDHLNIE 86
Cdd:PLN02578 75 GHKIHYVVQGEGLPIVLIHGFGASAFHWRYNIPELAKKYKVYALDLLGFGWSDkALIEYDAMV--WRDQVADFVKEVVKE 152
|
90 100 110
....*....|....*....|....*....|...
gi 2184988178 87 RCSIVGLSVGGMWGAIAALLAPERITGLVLMDT 119
Cdd:PLN02578 153 PAVLVGNSLGGFTALSTAVGYPELVAGVALLNS 185
|
|
| PRK11126 |
PRK11126 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional |
18-268 |
3.83e-06 |
|
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
Pssm-ID: 236855 [Multi-domain] Cd Length: 242 Bit Score: 46.76 E-value: 3.83e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 18 TGPVVLLGHSYLWDKGMWSAQLDTLaSQYRVIVPDLWGHGESDGFPegTRNLDDLTRHALALLDHLNIERCSIVGLSVGG 97
Cdd:PRK11126 1 GLPWLVFLHGLLGSGQDWQPVGEAL-PDYPRLYIDLPGHGGSAAIS--VDGFADVSRLLSQTLQSYNILPYWLVGYSLGG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 98 ---MWGAIAALlaPERITGLVLMDTYLGKETEATKAyyfsliNKLEETGAFPAPlldivvpifFRpgidpQSPL------ 168
Cdd:PRK11126 78 riaMYYACQGL--AGGLCGLIVEGGNPGLQNAEERQ------ARWQNDRQWAQR---------FR-----QEPLeqvlad 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 169 -YQafRAALAGMNAEQlRQTiaplgrMIFGRDDRLG-----------------LIEQLNADTT--LVMCGDADiprppEE 228
Cdd:PRK11126 136 wYQ--QPVFASLNAEQ-RQQ------LVAKRSNNNGaavaamleatslakqpdLRPALQALTFpfYYLCGERD-----SK 201
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 2184988178 229 TREMAGLIGCPYVLVPEAGHIANLENPDFVSGALMTFLAR 268
Cdd:PRK11126 202 FQALAQQLALPLHVIPNAGHNAHRENPAAFAASLAQILRL 241
|
|
| PLN02980 |
PLN02980 |
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ... |
15-269 |
3.43e-05 |
|
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding
Pssm-ID: 215530 [Multi-domain] Cd Length: 1655 Bit Score: 45.23 E-value: 3.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 15 DQGTGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGFPEGTRNLDD--LTRHALA-----LLDHLNIER 87
Cdd:PLN02980 1367 QNAEGSVVLFLHGFLGTGEDWIPIMKAISGSARCISIDLPGHGGSKIQNHAKETQTEptLSVELVAdllykLIEHITPGK 1446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 88 CSIVGLSVGGMWGAIAALLAPERITGLVLMDTYLGKETEATKAyyFSLINKLEETGAFPAPLLDIVVPIFFRPGI----- 162
Cdd:PLN02980 1447 VTLVGYSMGARIALYMALRFSDKIEGAVIISGSPGLKDEVARK--IRSAKDDSRARMLIDHGLEIFLENWYSGELwkslr 1524
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 163 -DPQspLYQAFRAALAGMNAEQLRQTIAPL--GRMIFGRDDrlglIEQLNADTTLVMcGDADIpRPPEETREMAGLIG-- 237
Cdd:PLN02980 1525 nHPH--FNKIVASRLLHKDVPSLAKLLSDLsiGRQPSLWED----LKQCDTPLLLVV-GEKDV-KFKQIAQKMYREIGks 1596
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 2184988178 238 -----------CPYVLVPEAGHIANLENPDFVSGALMTFLARV 269
Cdd:PLN02980 1597 kesgndkgkeiIEIVEIPNCGHAVHLENPLPVIRALRKFLTRL 1639
|
|
| PRK05855 |
PRK05855 |
SDR family oxidoreductase; |
7-104 |
9.12e-05 |
|
SDR family oxidoreductase;
Pssm-ID: 235628 [Multi-domain] Cd Length: 582 Bit Score: 43.43 E-value: 9.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 7 DGKALHYSDQG--TGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGfPEGTRN--LDDLTRHALALLDH 82
Cdd:PRK05855 11 DGVRLAVYEWGdpDRPTVVLVHGYPDNHEVWDGVAPLLADRFRVVAYDVRGAGRSSA-PKRTAAytLARLADDFAAVIDA 89
|
90 100
....*....|....*....|..
gi 2184988178 83 LNIERcsIVGLsVGGMWGAIAA 104
Cdd:PRK05855 90 VSPDR--PVHL-LAHDWGSIQG 108
|
|
| PRK10349 |
PRK10349 |
pimeloyl-ACP methyl ester esterase BioH; |
16-115 |
5.39e-04 |
|
pimeloyl-ACP methyl ester esterase BioH;
Pssm-ID: 137836 [Multi-domain] Cd Length: 256 Bit Score: 40.39 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 16 QGTGPVVLLgHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGFpeGTRNLDDLTRHALALLDhlniERCSIVGLSV 95
Cdd:PRK10349 11 QGNVHLVLL-HGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGF--GALSLADMAEAVLQQAP----DKAIWLGWSL 83
|
90 100
....*....|....*....|
gi 2184988178 96 GGMWGAIAALLAPERITGLV 115
Cdd:PRK10349 84 GGLVASQIALTHPERVQALV 103
|
|
| PLN02679 |
PLN02679 |
hydrolase, alpha/beta fold family protein |
14-118 |
1.15e-03 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 178283 [Multi-domain] Cd Length: 360 Bit Score: 39.82 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 14 SDQGTGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGFPEGTRNLDDLTRHALALLDHLNIERCSIVGL 93
Cdd:PLN02679 83 EVTSSGPPVLLVHGFGASIPHWRRNIGVLAKNYTVYAIDLLGFGASDKPPGFSYTMETWAELILDFLEEVVQKPTVLIGN 162
|
90 100
....*....|....*....|....*.
gi 2184988178 94 SVGGMWGAIAALLAPER-ITGLVLMD 118
Cdd:PLN02679 163 SVGSLACVIAASESTRDlVRGLVLLN 188
|
|
| PLN02894 |
PLN02894 |
hydrolase, alpha/beta fold family protein |
20-117 |
2.99e-03 |
|
hydrolase, alpha/beta fold family protein
Pssm-ID: 215484 [Multi-domain] Cd Length: 402 Bit Score: 38.74 E-value: 2.99e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 20 PVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDLWGHGESDGFPEGTRNlddlTRHALA-LLDHL-------NIERCSIV 91
Cdd:PLN02894 106 PTLVMVHGYGASQGFFFRNFDALASRFRVIAIDQLGWGGSSRPDFTCKS----TEETEAwFIDSFeewrkakNLSNFILL 181
|
90 100
....*....|....*....|....*.
gi 2184988178 92 GLSVGGMWGAIAALLAPERITGLVLM 117
Cdd:PLN02894 182 GHSFGGYVAAKYALKHPEHVQHLILV 207
|
|
| PRK08775 |
PRK08775 |
homoserine O-succinyltransferase; |
32-116 |
3.94e-03 |
|
homoserine O-succinyltransferase;
Pssm-ID: 181553 [Multi-domain] Cd Length: 343 Bit Score: 38.23 E-value: 3.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 32 KGMWSAQ------LDTlaSQYRVIVPDLWGhgeSDGFPEGTRNLDDLTRHALALLDHLNIERCS-IVGLSVGGMWGAIAA 104
Cdd:PRK08775 82 KGWWEGLvgsgraLDP--ARFRLLAFDFIG---ADGSLDVPIDTADQADAIALLLDALGIARLHaFVGYSYGALVGLQFA 156
|
90
....*....|..
gi 2184988178 105 LLAPERITGLVL 116
Cdd:PRK08775 157 SRHPARVRTLVV 168
|
|
| Axe1 |
COG3458 |
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, ... |
15-116 |
4.53e-03 |
|
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442681 [Multi-domain] Cd Length: 318 Bit Score: 37.86 E-value: 4.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2184988178 15 DQGTGPVVLLGHSYLWDKGMWSAQLDTLASQYRVIVPDL------WGHGESDGFPEG-------TRNLDDLTRH------ 75
Cdd:COG3458 78 GEGPLPAVVEFHGYGGGRGLPHEDLDWAAAGYAVLVMDTrgqgssWGDTPDPGGYSGgalpgymTRGIDDPDTYyyrrvy 157
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2184988178 76 --------ALALLDHLNIERCSIVGLSVGGMWGAIAALLAPeRITGLVL 116
Cdd:COG3458 158 ldavravdALRSLPEVDGKRIGVTGGSQGGGLALAAAALDP-RVKAAAA 205
|
|
|