NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2184180798|ref|WP_236105221|]
View 

MULTISPECIES: ATP-binding protein, partial [Enterobacterales]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
P-loop_NTPase super family cl38936
P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain ...
1-30 8.80e-15

P-loop containing Nucleoside Triphosphate Hydrolases; Members of the P-loop NTPase domain superfamily are characterized by a conserved nucleotide phosphate-binding motif, also referred to as the Walker A motif (GxxxxGK[S/T], where x is any residue), and the Walker B motif (hhhh[D/E], where h is a hydrophobic residue). The Walker A and B motifs bind the beta-gamma phosphate moiety of the bound nucleotide (typically ATP or GTP) and the Mg2+ cation, respectively. The P-loop NTPases are involved in diverse cellular functions, and they can be divided into two major structural classes: the KG (kinase-GTPase) class which includes Ras-like GTPases and its circularly permutated YlqF-like; and the ASCE (additional strand catalytic E) class which includes ATPase Binding Cassette (ABC), DExD/H-like helicases, 4Fe-4S iron sulfur cluster binding proteins of NifH family, RecA-like F1-ATPases, and ATPases Associated with a wide variety of Activities (AAA). Also included are a diverse set of nucleotide/nucleoside kinase families.


The actual alignment was detected with superfamily member PRK09183:

Pssm-ID: 476819  Cd Length: 259  Bit Score: 63.57  E-value: 8.80e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 2184180798   1 HHSHVVQIKGESYRLRQKRKAGVIAEANPE 30
Cdd:PRK09183  230 HHSHVVQIKGESYRLKQKRKAGVIAEANPE 259
 
Name Accession Description Interval E-value
PRK09183 PRK09183
transposase/IS protein; Provisional
1-30 8.80e-15

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 63.57  E-value: 8.80e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 2184180798   1 HHSHVVQIKGESYRLRQKRKAGVIAEANPE 30
Cdd:PRK09183  230 HHSHVVQIKGESYRLKQKRKAGVIAEANPE 259
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
1-21 9.88e-08

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 44.36  E-value: 9.88e-08
                          10        20
                  ....*....|....*....|.
gi 2184180798   1 HHSHVVQIKGESYRLRQKRKA 21
Cdd:pfam01695 218 HHCHIVPIKGESYRLKTKSEA 238
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
1-17 1.28e-06

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 41.30  E-value: 1.28e-06
                          10
                  ....*....|....*..
gi 2184180798   1 HHSHVVQIKGESYRLRQ 17
Cdd:NF038214  216 HHAHILELKGESYRLKE 232
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-18 6.99e-06

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 38.99  E-value: 6.99e-06
                          10
                  ....*....|....*...
gi 2184180798   1 HHSHVVQIKGESYRLRQK 18
Cdd:COG1484   225 HHAHIIELKGESYRLKEA 242
 
Name Accession Description Interval E-value
PRK09183 PRK09183
transposase/IS protein; Provisional
1-30 8.80e-15

transposase/IS protein; Provisional


Pssm-ID: 181681  Cd Length: 259  Bit Score: 63.57  E-value: 8.80e-15
                          10        20        30
                  ....*....|....*....|....*....|
gi 2184180798   1 HHSHVVQIKGESYRLRQKRKAGVIAEANPE 30
Cdd:PRK09183  230 HHSHVVQIKGESYRLKQKRKAGVIAEANPE 259
IstB_IS21 pfam01695
IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is ...
1-21 9.88e-08

IstB-like ATP binding protein; This protein contains an ATP/GTP binding P-loop motif. It is found associated with IS21 family insertion sequences. The function of this protein is unknown, but it may perform a transposase function.


Pssm-ID: 426385 [Multi-domain]  Cd Length: 238  Bit Score: 44.36  E-value: 9.88e-08
                          10        20
                  ....*....|....*....|.
gi 2184180798   1 HHSHVVQIKGESYRLRQKRKA 21
Cdd:pfam01695 218 HHCHIVPIKGESYRLKTKSEA 238
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
1-17 1.28e-06

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 41.30  E-value: 1.28e-06
                          10
                  ....*....|....*..
gi 2184180798   1 HHSHVVQIKGESYRLRQ 17
Cdd:NF038214  216 HHAHILELKGESYRLKE 232
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
1-18 6.99e-06

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 38.99  E-value: 6.99e-06
                          10
                  ....*....|....*...
gi 2184180798   1 HHSHVVQIKGESYRLRQK 18
Cdd:COG1484   225 HHAHIIELKGESYRLKEA 242
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH