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Conserved domains on  [gi|2176775230|ref|WP_234062316|]
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DUF3575 domain-containing protein, partial [Bacteroides salyersiae]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3575 super family cl13526
Protein of unknown function (DUF3575); This family of proteins are functionally ...
 212-344 3.86e-36

Protein of unknown function (DUF3575); This family of proteins are functionally uncharacterized. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.


The actual alignment was detected with superfamily member pfam12099:

Pssm-ID: 432330  Cd Length: 177  Bit Score: 128.86  E-value: 3.86e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2176775230 212 YMAVKTNMLYDALLVPNIGVEFYVGKNWSLAGNWMYAWWKSDRHHnYWRLYGGDLEVRRWFGRkasekPLAGHHIGLYGR 291
Cdd:pfam12099  17 KVAVKTNLLYWATTTPNLGAEFALGKKWTLDLSGNYNPWTFSDNK-KWKHWLVQPEVRYWFCE-----PFNGHFLGLHAL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2176775230 292 IFTYDF-----ETGGTGYMGgkpggtlwdkMNYSVGLEYGYSLPVARRLNLDFVIGVG 344
Cdd:pfam12099  91 GGQYNVggldkILKDYRYEG----------WAYGGGLSYGYSWILSKRWNLEASIGLG 138
OmpA_C-like super family cl30079
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 3-68 4.49e-04

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


The actual alignment was detected with superfamily member cd07185:

Pssm-ID: 453091 [Multi-domain]  Cd Length: 106  Bit Score: 39.07  E-value: 4.49e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2176775230   3 IYFHKGRTEIDlslRDNRRSLEKISRRILEYrPDTafsicKIMVVGAASPEGSIELNRRLSELRAK 68
Cdd:cd07185     4 IYFDFGSAELT---PEAKPLLDKLAEVLKKN-PDA-----KIRIEGHTDSRGSDAYNQELSERRAE 60
 
Name Accession Description Interval E-value
DUF3575 pfam12099
Protein of unknown function (DUF3575); This family of proteins are functionally ...
 212-344 3.86e-36

Protein of unknown function (DUF3575); This family of proteins are functionally uncharacterized. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.


Pssm-ID: 432330  Cd Length: 177  Bit Score: 128.86  E-value: 3.86e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2176775230 212 YMAVKTNMLYDALLVPNIGVEFYVGKNWSLAGNWMYAWWKSDRHHnYWRLYGGDLEVRRWFGRkasekPLAGHHIGLYGR 291
Cdd:pfam12099  17 KVAVKTNLLYWATTTPNLGAEFALGKKWTLDLSGNYNPWTFSDNK-KWKHWLVQPEVRYWFCE-----PFNGHFLGLHAL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2176775230 292 IFTYDF-----ETGGTGYMGgkpggtlwdkMNYSVGLEYGYSLPVARRLNLDFVIGVG 344
Cdd:pfam12099  91 GGQYNVggldkILKDYRYEG----------WAYGGGLSYGYSWILSKRWNLEASIGLG 138
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 3-68 4.49e-04

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 39.07  E-value: 4.49e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2176775230   3 IYFHKGRTEIDlslRDNRRSLEKISRRILEYrPDTafsicKIMVVGAASPEGSIELNRRLSELRAK 68
Cdd:cd07185     4 IYFDFGSAELT---PEAKPLLDKLAEVLKKN-PDA-----KIRIEGHTDSRGSDAYNQELSERRAE 60
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 2-68 5.86e-04

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 41.31  E-value: 5.86e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2176775230   2 KIYFHKGRTEIDlslRDNRRSLEKISRRILEYrPDTafsicKIMVVGAASPEGSIELNRRLSELRAK 68
Cdd:COG2885   188 NVYFDFDSAELT---PEAKAALDELAALLKEN-PDL-----RIEIEGHTDSRGSDAYNLALSERRAE 245
 
Name Accession Description Interval E-value
DUF3575 pfam12099
Protein of unknown function (DUF3575); This family of proteins are functionally ...
 212-344 3.86e-36

Protein of unknown function (DUF3575); This family of proteins are functionally uncharacterized. This family is only found in bacteria. Proteins in this family are typically between 187 to 236 amino acids in length.


Pssm-ID: 432330  Cd Length: 177  Bit Score: 128.86  E-value: 3.86e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2176775230 212 YMAVKTNMLYDALLVPNIGVEFYVGKNWSLAGNWMYAWWKSDRHHnYWRLYGGDLEVRRWFGRkasekPLAGHHIGLYGR 291
Cdd:pfam12099  17 KVAVKTNLLYWATTTPNLGAEFALGKKWTLDLSGNYNPWTFSDNK-KWKHWLVQPEVRYWFCE-----PFNGHFLGLHAL 90

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 2176775230 292 IFTYDF-----ETGGTGYMGgkpggtlwdkMNYSVGLEYGYSLPVARRLNLDFVIGVG 344
Cdd:pfam12099  91 GGQYNVggldkILKDYRYEG----------WAYGGGLSYGYSWILSKRWNLEASIGLG 138
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 3-68 4.49e-04

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 39.07  E-value: 4.49e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2176775230   3 IYFHKGRTEIDlslRDNRRSLEKISRRILEYrPDTafsicKIMVVGAASPEGSIELNRRLSELRAK 68
Cdd:cd07185     4 IYFDFGSAELT---PEAKPLLDKLAEVLKKN-PDA-----KIRIEGHTDSRGSDAYNQELSERRAE 60
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 2-68 5.86e-04

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 41.31  E-value: 5.86e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 2176775230   2 KIYFHKGRTEIDlslRDNRRSLEKISRRILEYrPDTafsicKIMVVGAASPEGSIELNRRLSELRAK 68
Cdd:COG2885   188 NVYFDFDSAELT---PEAKAALDELAALLKEN-PDL-----RIEIEGHTDSRGSDAYNLALSERRAE 245
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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