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Conserved domains on  [gi|2152203556|ref|WP_229098406|]
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STN domain-containing protein, partial [Odoribacter splanchnicus]

Protein Classification

STN domain-containing protein( domain architecture ID 10541884)

STN (secretin and TonB N-terminal) domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
OMP_RagA_SusC super family cl37378
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 124-303 8.17e-60

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


The actual alignment was detected with superfamily member TIGR04056:

Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 205.90  E-value: 8.17e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 124 KIRGRVTDTKSEPLAGVTILIEGTCIGTTTDSNGNYVFTIPDIDKINIiySFIGMAPYKVAYTGQENINVILKESAETMD 203
Cdd:TIGR04056   2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVF--SYIGYKTQEVKVKGQKNLNITLKEDTQELD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 204 EVVVTGYQTLRKSDVVGSVSTVKASDIMMPVYTSIDQMLQGRVAGMMVMNTSSRVGTSPKIRIRGTSTILGNQDPLWVVD 283
Cdd:TIGR04056  80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVID 159

                         170       180
                  ....*....|....*....|
gi 2152203556 284 GVIQPDPIplnqNDLMVDDI 303
Cdd:TIGR04056 160 GVPRDNGL----SDLNPEDI 175
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 68-117 4.27e-07

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


:

Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 45.97  E-value: 4.27e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2152203556  68 FMYSNQDVAAIKNISVQREGVSVQEILDIVLKGHNLTYLIEDKIIFIKKQ 117
Cdd:pfam07660   2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRPK 51
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 124-303 8.17e-60

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 205.90  E-value: 8.17e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 124 KIRGRVTDTKSEPLAGVTILIEGTCIGTTTDSNGNYVFTIPDIDKINIiySFIGMAPYKVAYTGQENINVILKESAETMD 203
Cdd:TIGR04056   2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVF--SYIGYKTQEVKVKGQKNLNITLKEDTQELD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 204 EVVVTGYQTLRKSDVVGSVSTVKASDIMMPVYTSIDQMLQGRVAGMMVMNTSSRVGTSPKIRIRGTSTILGNQDPLWVVD 283
Cdd:TIGR04056  80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVID 159

                         170       180
                  ....*....|....*....|
gi 2152203556 284 GVIQPDPIplnqNDLMVDDI 303
Cdd:TIGR04056 160 GVPRDNGL----SDLNPEDI 175
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 125-207 9.71e-18

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 76.48  E-value: 9.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 125 IRGRVTDTKS-EPLAGVTILIEGTCIGTTTDSNGNYVFTIPDIDKINIIYSFIGMAPYKVAYTGQE----NINVILKESA 199
Cdd:pfam13715   1 ISGTVVDENTgEPLPGATVYVKGTTKGTVTDADGNFELKNLPAGTYTLVVSFVGYKTQEKKVTVSNdntlDVNFLLKEDA 80


                  ....*...
gi 2152203556 200 ETMDEVVV 207
Cdd:pfam13715  81 LLLDEVVV 88
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
205-305 2.08e-13

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 69.13  E-value: 2.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 205 VVVTGYQ-TLRKSDVVGSVSTVKASDIMMPVYTSIDQMLQgRVAGMMVmNTSSRVGTSPKIRIRGTSTilgnQDPLWVVD 283
Cdd:COG4206     1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQV-SSSGGPGSAASISIRGLGS----NQTLVLID 74

                          90       100
                  ....*....|....*....|....*...
gi 2152203556 284 GVIQPDPIpLNQNDL------MVDDISV 305
Cdd:COG4206    75 GVPLNDPS-LGGVDLslippdDIERIEV 101
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 68-117 4.27e-07

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 45.97  E-value: 4.27e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2152203556  68 FMYSNQDVAAIKNISVQREGVSVQEILDIVLKGHNLTYLIEDKIIFIKKQ 117
Cdd:pfam07660   2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRPK 51
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 66-117 9.66e-06

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 42.11  E-value: 9.66e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2152203556   66 YRFMYSNQDVAAiKNISVQREGVSVQEILDIVLKGHNLTYL-IEDKIIFIKKQ 117
Cdd:smart00965   1 LNFVYDPALVAG-RRVSLLLGNVTVEQALDRLLAGTGLTYRrIGGNTIVLSPA 52
 
Name Accession Description Interval E-value
OMP_RagA_SusC TIGR04056
TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade ...
 124-303 8.17e-60

TonB-linked outer membrane protein, SusC/RagA family; This model describes a distinctive clade among the TonB-linked outer membrane proteins (OMP). Members of this family are restricted to the Bacteriodetes lineage (except for Gemmatimonas aurantiaca T-27 from the novel phylum Gemmatimonadetes) and occur in high copy numbers, with over 100 members from Bacteroides thetaiotaomicron VPI-5482 alone. Published descriptions of members of this family are available for RagA from Porphyromonas gingivalis, SusC from Bacteroides thetaiotaomicron, and OmpW from Bacteroides caccae. Members form pairs with members of the SusD/RagB family (pfam07980). Transporter complexes including these outer membrane proteins are likely to import large degradation products of proteins (e.g. RagA) or carbohydrates (e.g. SusC) as nutrients, rather than siderophores. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 274948 [Multi-domain]  Cd Length: 981  Bit Score: 205.90  E-value: 8.17e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 124 KIRGRVTDTKSEPLAGVTILIEGTCIGTTTDSNGNYVFTIPDIDKINIiySFIGMAPYKVAYTGQENINVILKESAETMD 203
Cdd:TIGR04056   2 TVTGVVVDETGEPLIGASVVVKGTTNGTITDIDGNFSLKVPPGAVLVF--SYIGYKTQEVKVKGQKNLNITLKEDTQELD 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 204 EVVVTGYQTLRKSDVVGSVSTVKASDIMMPVYTSIDQMLQGRVAGMMVMNTSSRVGTSPKIRIRGTSTILGNQDPLWVVD 283
Cdd:TIGR04056  80 EVVVVGYGTQKKKSLTGAVSTVKAKELKKVPVSNLSNALQGKVAGVIITQSSGEPGGDAEIWIRGISSFGGNNSPLYVID 159

                         170       180
                  ....*....|....*....|
gi 2152203556 284 GVIQPDPIplnqNDLMVDDI 303
Cdd:TIGR04056 160 GVPRDNGL----SDLNPEDI 175
CarbopepD_reg_2 pfam13715
CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, ...
 125-207 9.71e-18

CarboxypepD_reg-like domain; This domain family is found in bacteria, archaea and eukaryotes, and is approximately 90 amino acids in length. The family is found in association with pfam07715 and pfam00593.


Pssm-ID: 433425 [Multi-domain]  Cd Length: 88  Bit Score: 76.48  E-value: 9.71e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 125 IRGRVTDTKS-EPLAGVTILIEGTCIGTTTDSNGNYVFTIPDIDKINIIYSFIGMAPYKVAYTGQE----NINVILKESA 199
Cdd:pfam13715   1 ISGTVVDENTgEPLPGATVYVKGTTKGTVTDADGNFELKNLPAGTYTLVVSFVGYKTQEKKVTVSNdntlDVNFLLKEDA 80


                  ....*...
gi 2152203556 200 ETMDEVVV 207
Cdd:pfam13715  81 LLLDEVVV 88
BtuB COG4206
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
205-305 2.08e-13

Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];


Pssm-ID: 443355 [Multi-domain]  Cd Length: 276  Bit Score: 69.13  E-value: 2.08e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 205 VVVTGYQ-TLRKSDVVGSVSTVKASDIMMPVYTSIDQMLQgRVAGMMVmNTSSRVGTSPKIRIRGTSTilgnQDPLWVVD 283
Cdd:COG4206     1 VVVTATRlEQSKSDLTGSVTVIDAEELERSGATSLADALR-RVPGVQV-SSSGGPGSAASISIRGLGS----NQTLVLID 74

                          90       100
                  ....*....|....*....|....*...
gi 2152203556 284 GVIQPDPIpLNQNDL------MVDDISV 305
Cdd:COG4206    75 GVPLNDPS-LGGVDLslippdDIERIEV 101
FepA COG4771
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ...
 195-305 2.92e-11

Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];


Pssm-ID: 443803 [Multi-domain]  Cd Length: 612  Bit Score: 64.11  E-value: 2.92e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 195 LKESAETMDEVVVTGYQTLRK-SDVVGSVSTVKASDIMMPVYTSIDQMLQgRVAGMMVMNTSSRVGTSPkIRIRGtstiL 273
Cdd:COG4771    20 LAEDATELEEVVVTATRTEQSlSDAPASVSVITAEEIEKLGATDLADALR-LLPGVSVTRSGGRGGSSG-ISIRG----L 93

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 2152203556 274 GNQDPLWVVDGVIQPDPIPLNQNDL------MVDDISV 305
Cdd:COG4771    94 GGDRVLVLIDGVPVNNPALGGGGDLsyippdDIERIEV 131
CirA COG1629
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
202-301 1.65e-10

Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];


Pssm-ID: 441236 [Multi-domain]  Cd Length: 644  Bit Score: 61.77  E-value: 1.65e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 202 MDEVVVTGYQT-LRKSDVVGSVSTVKASDIMMPVYTSIDQMLQgRVAGMMVMNTSsrvGTSPKIRIRGTSTilGNQDPLW 280
Cdd:COG1629     1 LEEVVVTATRTdESLQDVPGSVSVISREQLEDQPATDLGDLLR-RVPGVSVTSAG---GGAGQISIRGFGG--GGNRVLV 74

                          90       100
                  ....*....|....*....|.
gi 2152203556 281 VVDGVIQPDPIPLNQNDLMVD 301
Cdd:COG1629    75 LVDGVPLNDPSGGDGGLSYID 95
CarboxypepD_reg pfam13620
Carboxypeptidase regulatory-like domain;
125-183 2.27e-07

Carboxypeptidase regulatory-like domain;


Pssm-ID: 433354 [Multi-domain]  Cd Length: 81  Bit Score: 47.66  E-value: 2.27e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2152203556 125 IRGRVTDTKSEPLAGVTILIE----GTCIGTTTDSNGNYVFTIPDIDKINIIYSFIGMAPYKV 183
Cdd:pfam13620   2 ISGTVTDPSGAPVPGATVTVTntdtGTVRTTTTDADGRYRFPGLPPGTYTVTVSAPGFKTATR 64
STN pfam07660
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 68-117 4.27e-07

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 429580 [Multi-domain]  Cd Length: 51  Bit Score: 45.97  E-value: 4.27e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 2152203556  68 FMYSNQDVAAIKNISVQREGVSVQEILDIVLKGHNLTYLIEDKIIFIKKQ 117
Cdd:pfam07660   2 ILYDSDLVDGKQSVSLNVGNVTLEEALDQLLAGTGLSYEIGGNTIVLRPK 51
Plug pfam07715
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ...
 214-301 1.37e-06

TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.


Pssm-ID: 462243 [Multi-domain]  Cd Length: 107  Bit Score: 46.11  E-value: 1.37e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2152203556 214 RKSDVVGSVSTVKASDIMMPVYTSIDQMLQgRVAGmmVMNTSSRVGTSPKIRIRGtstiLGNQDPLWVVDGVIQPDPIPL 293
Cdd:pfam07715   1 DLRDTPGSVSVVTAEDIEDQGATNLADALR-GVPG--VSVSSGGGGGGSSISIRG----FGSNRVLVLVDGVPLNSGGGG 73


                  ....*...
gi 2152203556 294 NQNDLMVD 301
Cdd:pfam07715  74 SVDLNSID 81
STN smart00965
Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of ...
 66-117 9.66e-06

Secretin and TonB N terminus short domain; This is a short domain found at the N-terminus of the Secretins of the bacterial type II/III secretory system as well as the TonB-dependent receptor proteins. These proteins are involved in TonB-dependent active uptake of selective substrates.


Pssm-ID: 198033 [Multi-domain]  Cd Length: 52  Bit Score: 42.11  E-value: 9.66e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 2152203556   66 YRFMYSNQDVAAiKNISVQREGVSVQEILDIVLKGHNLTYL-IEDKIIFIKKQ 117
Cdd:smart00965   1 LNFVYDPALVAG-RRVSLLLGNVTVEQALDRLLAGTGLTYRrIGGNTIVLSPA 52
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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