|
Name |
Accession |
Description |
Interval |
E-value |
| PBP2_Opu_like_1 |
cd13609 |
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ... |
256-518 |
1.21e-144 |
|
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270327 Cd Length: 263 Bit Score: 416.23 E-value: 1.21e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13609 1 TIVIGSKNFTEQLILGNMYADLIEANTDIKVERKLNLGGSSVCFSALKNGDIDMYVDYTGTILVNILKEPPISDPDEVYN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFKDA 415
Cdd:cd13609 81 TVKELMKEKYNLEVLKPLGFNNTYTLAVRKETAEKYNLKTISDLAKVSDELTLGCTLEFLNREDGLPGLEKTYGLNFKDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 416 KGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDTM 495
Cdd:cd13609 161 KGLDGSLRYTALENGEVDVIDAFSTDGLLKKFDLVVLEDDKNFFPPYYAVPLVREETLEKYPELEDVLNKLAGKISEETM 240
|
250 260
....*....|....*....|...
gi 2124019877 496 RELNYQVDVEHKSPKEVAHDFLV 518
Cdd:cd13609 241 RELNYKVDELGKDPEDVAHEFLV 263
|
|
| OsmF |
COG1732 |
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ... |
224-520 |
1.55e-129 |
|
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441338 [Multi-domain] Cd Length: 294 Bit Score: 378.72 E-value: 1.55e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 224 RRRQKWSVGVVVALLVFMFGQNVYAnlvKDPNTIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTQVLFSAME 303
Cdd:COG1732 2 KRLLLLALALAAALALAGCGLASAA---AAGDTIVVGSKNFTEQEILAEIYAQALEAA-GLKVERKLNLGGTEVVRQALK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 304 KGDLDAYIDYTGTAYVDILKHDPISDEQEVYDTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVA 383
Cdd:COG1732 78 SGEIDLYPEYTGTALTTYLKEDPITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 384 SSLKAGTTLEFLNRQDGLRGVQNEYGFTFKDAKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYY 463
Cdd:COG1732 158 GELTLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYN 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2124019877 464 GVPLVRQETIEEHPELQDVINRMMATLDTDTMRELNYQVDVEHKSPKEVAHDFLVAK 520
Cdd:COG1732 238 AAPLVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
|
|
| OpuBB |
COG1174 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
2-206 |
1.02e-92 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440787 [Multi-domain] Cd Length: 212 Bit Score: 281.56 E-value: 1.02e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 2 GIFSYMFENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTL 81
Cdd:COG1174 4 SLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 82 PSVIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG 161
Cdd:COG1174 84 PAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAG 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2124019877 162 GLGFLVFSGISSVNNGMILAGAIPACILALAIDWVLSQVESLVTP 206
Cdd:COG1174 164 GLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTP 208
|
|
| OpuAC |
pfam04069 |
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ... |
256-517 |
3.33e-66 |
|
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).
Pssm-ID: 397954 [Multi-domain] Cd Length: 257 Bit Score: 214.88 E-value: 3.33e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIEShLGAGGTQVLFSAMEKGDLDAYID-YTGTAYvdilkhdpisdeqevy 334
Cdd:pfam04069 2 TIVIGSKNWTEQEILANIAAQLLEAL-GYVVEL-VGLGSSAVLFAALASGDIDLYPEeWTGTTY---------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 335 DTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGL------RGVQNEY 408
Cdd:pfam04069 64 EAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLKAY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 409 GFT-----FKDAKGIDgATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPP-YYGVPLVRQETIEEHPELQDV 482
Cdd:pfam04069 144 GLDkyelvEGSEAAMD-ALIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVAAF 222
|
250 260 270
....*....|....*....|....*....|....*
gi 2124019877 483 INRMmaTLDTDTMRELNYQVDVEHKSPKEVAHDFL 517
Cdd:pfam04069 223 LNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWL 255
|
|
| PRK10952 |
PRK10952 |
proline/glycine betaine ABC transporter permease ProW; |
33-194 |
8.53e-27 |
|
proline/glycine betaine ABC transporter permease ProW;
Pssm-ID: 236805 Cd Length: 355 Bit Score: 111.34 E-value: 8.53e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 33 ILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPSVIVVFLYSLLPIVKNTYIGISQISPGTIE 112
Cdd:PRK10952 161 IVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 113 AARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAGGLGFLVFSGISSVNNGMILAGAIPACILALA 192
Cdd:PRK10952 241 ASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAII 320
|
..
gi 2124019877 193 ID 194
Cdd:PRK10952 321 LD 322
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
18-193 |
5.11e-19 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 85.02 E-value: 5.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 18 LLEHIQLTAIAVGLAILVGLPLGILI-SYVKPLNKPVMGATNLIQAVPSMALL---------GFAIPLLGIGTLPSVIVV 87
Cdd:cd06261 1 LLNTLLLALIATLLALVLGLLLGIILaRKRGKLDRLLRRIIDLLLSLPSLVLGlllvllfgvLLGWGILPGLGLPALILA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 88 FLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG---GLG 164
Cdd:cd06261 81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPG 160
|
170 180
....*....|....*....|....*....
gi 2124019877 165 FLVFSGISSVNNGMILAGAIPACILALAI 193
Cdd:cd06261 161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
36-193 |
1.16e-18 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 83.89 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 36 GLPLGILI--SYVKPLNKPVMGATNLIQAVPSMALLGFAIPL-----LGIGTLPSVIVVFLYSLLPIVKNTYIGISQISP 108
Cdd:pfam00528 1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 109 GTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG-GLGFLVFSGISSVNNGMILAGAIPAC 187
Cdd:pfam00528 81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAA 160
|
....*.
gi 2124019877 188 ILALAI 193
Cdd:pfam00528 161 LILLLL 166
|
|
| PhnE |
TIGR01097 |
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ... |
8-196 |
3.78e-13 |
|
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]
Pssm-ID: 273441 [Multi-domain] Cd Length: 250 Bit Score: 69.49 E-value: 3.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 8 FENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGIL----ISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPS 83
Cdd:TIGR01097 50 WSYLPRILKALLETLAMAILGTVLAAVLAVPLALLaarnITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 84 VIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMA--------GVRISAVtaVGlmtia 155
Cdd:TIGR01097 130 VLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAV--LG----- 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2124019877 156 aFIGAGGLGFLVFSGISSVN---NGMILAGAIpacILALAIDWV 196
Cdd:TIGR01097 203 -LVGAGGIGLELDTAIGLFDydeVSAIILVIL---VVVVIIDLI 242
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PBP2_Opu_like_1 |
cd13609 |
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ... |
256-518 |
1.21e-144 |
|
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270327 Cd Length: 263 Bit Score: 416.23 E-value: 1.21e-144
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13609 1 TIVIGSKNFTEQLILGNMYADLIEANTDIKVERKLNLGGSSVCFSALKNGDIDMYVDYTGTILVNILKEPPISDPDEVYN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFKDA 415
Cdd:cd13609 81 TVKELMKEKYNLEVLKPLGFNNTYTLAVRKETAEKYNLKTISDLAKVSDELTLGCTLEFLNREDGLPGLEKTYGLNFKDV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 416 KGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDTM 495
Cdd:cd13609 161 KGLDGSLRYTALENGEVDVIDAFSTDGLLKKFDLVVLEDDKNFFPPYYAVPLVREETLEKYPELEDVLNKLAGKISEETM 240
|
250 260
....*....|....*....|...
gi 2124019877 496 RELNYQVDVEHKSPKEVAHDFLV 518
Cdd:cd13609 241 RELNYKVDELGKDPEDVAHEFLV 263
|
|
| OsmF |
COG1732 |
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system ... |
224-520 |
1.55e-129 |
|
Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441338 [Multi-domain] Cd Length: 294 Bit Score: 378.72 E-value: 1.55e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 224 RRRQKWSVGVVVALLVFMFGQNVYAnlvKDPNTIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTQVLFSAME 303
Cdd:COG1732 2 KRLLLLALALAAALALAGCGLASAA---AAGDTIVVGSKNFTEQEILAEIYAQALEAA-GLKVERKLNLGGTEVVRQALK 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 304 KGDLDAYIDYTGTAYVDILKHDPISDEQEVYDTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVA 383
Cdd:COG1732 78 SGEIDLYPEYTGTALTTYLKEDPITDPEEVYEAVKEALPEKNGLTWLDPAGFNNTYALAVTKETAEKYGLKTISDLAKVA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 384 SSLKAGTTLEFLNRQDGLRGVQNEYGFTFKDAKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYY 463
Cdd:COG1732 158 GELTLGADPEFAERPDGLPGLKKAYGFEFKEVKPMDTGLTYTALANGQVDVADAYTTDGRIAALDLVVLEDDKNFFPPYN 237
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 2124019877 464 GVPLVRQETIEEHPELQDVINRMMATLDTDTMRELNYQVDVEHKSPKEVAHDFLVAK 520
Cdd:COG1732 238 AAPLVRKEVLEKYPELAEVLNKLSGKLTTETMQELNYQVDVDGEDPADVAREFLKEK 294
|
|
| PBP2_osmoprotectants |
cd13528 |
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 ... |
256-517 |
2.48e-124 |
|
Substrate-binding domain of osmoregulatory ABC-type transporters; the type 2 periplasmic-binding protein fold; This family represents the periplasmic substrate-binding component of ABC transport systems that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, bacteria and archaea accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270246 [Multi-domain] Cd Length: 264 Bit Score: 364.61 E-value: 2.48e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHD-PISDEQEVY 334
Cdd:cd13528 1 TIVVGSKNFTEQYILGEMLAQLLEANTDLTVERKLNLGGTEVAFNALKNGDIDLYVEYTGTALLTILKEDaPITDPEEVY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 335 DTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFKD 414
Cdd:cd13528 81 EKVKKEYEEKFGLTWLDPLGFNNTYALAVRKDTAEKYGLKTISDLAPHSDQLVFGADPEFYERSDGLPGLKKTYGFDFKE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 415 AKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDT 494
Cdd:cd13528 161 VKTMDPGLTYEALDNGEVDVIDAFSTDGRIKAFDLVVLEDDKNFFPPYNAAPVVREDVLKKHPELEEVLNKLSGKLTDET 240
|
250 260
....*....|....*....|...
gi 2124019877 495 MRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13528 241 MQQLNYQVDVEGKDPEEVARDFL 263
|
|
| PBP2_ProWX |
cd13612 |
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; ... |
256-522 |
1.52e-100 |
|
Substrate-binding protein ProWX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWX of Helicobacter pylori is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270330 Cd Length: 267 Bit Score: 303.78 E-value: 1.52e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLG-AGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEqEVY 334
Cdd:cd13612 1 TIHIATKPMTEQYILGEMLKQLIEQDTDLKVELTKGvGGGTSNIHPAMVKGEFDLYPEYTGTGWLFVLKKDGTYSE-ELF 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 335 DTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFKD 414
Cdd:cd13612 80 DQLQKEYEEKYNLTWLGLYGFNNTYGLAVRKELAEKYNLKTYSDLAKVSNQLVFGAEYDFFEREDGYDALQKAYGFNFKK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 415 AKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDT 494
Cdd:cd13612 160 TVDMDIGLKYQAIESGKVDVINVFTTDGQLSDADIVVLEDDKGFFPSYYAGTVVREETLEKYPELEDVLEKLTGLISDED 239
|
250 260
....*....|....*....|....*...
gi 2124019877 495 MRELNYQVDVEHKSPKEVAHDFLVAKGL 522
Cdd:cd13612 240 MAEMNYQVEIEKKDPKDVAKEFLEEKGL 267
|
|
| PBP2_QAT_like |
cd13614 |
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 ... |
256-518 |
6.75e-99 |
|
Substrate-binding domain of quaternary amine ABC-type transporter; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative quaternary amine ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270332 Cd Length: 264 Bit Score: 299.30 E-value: 6.75e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEkNTNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13614 1 AIRVGSKNFTEQFILGEMYALALE-DAGIKVERKLNLGGTLIAHQALVNGEIDLYPEYTGTALLTVLKGEPSSDAKQVYK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYG-FTFKD 414
Cdd:cd13614 80 TVKDAYAEQFQLTWLEPAPFNNTYALVMTRETAEKYGIKTLSDLAKAAGELVFGGGPEFQDREDGLPGLKAKYGaFDFKE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 415 AKGID-GATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTD 493
Cdd:cd13614 160 FVQVDpLGLRYQALAQGQIDVAVGFGTDGQIAAYGLVVLEDDKNLFPPYQVAPVVRQDVLDANPKIAEVLNKLSALLDNE 239
|
250 260
....*....|....*....|....*
gi 2124019877 494 TMRELNYQVDVEHKSPKEVAHDFLV 518
Cdd:cd13614 240 TMQRLNYEVDGNKREPKDVAREFLK 264
|
|
| PBP2_ChoS |
cd13610 |
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; ... |
256-518 |
2.00e-93 |
|
Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270328 Cd Length: 264 Bit Score: 285.25 E-value: 2.00e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTN-IKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPIS-DEQEV 333
Cdd:cd13610 1 SIVIAGKLGSEPDILINMYKLLIEEETPdLQVTLKPNFGKTSFLFNALKSGDIDIYPEFTGTVLETLLKEPPKSnDPMEV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 334 YDTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFK 413
Cdd:cd13610 81 YEQARDGLAKQYQLTYLKPMAYNNTYALAVKKEFAKQHNLKTISDLQKVQDKLKAGFTLEFMDREDGYKGLQKAYGLNFN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 414 dAKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTD 493
Cdd:cd13610 161 -VKSMEPALRYQAINNGQVNVIDAYSTDSEIKQYDLVVLKDDKHLFPPYQGAPLMREEFLKKHPELVKALNKLAGKITDE 239
|
250 260
....*....|....*....|....*
gi 2124019877 494 TMRELNYQVDVEHKSPKEVAHDFLV 518
Cdd:cd13610 240 EMQEMNYRVDVKHKSAAKVAKEYLQ 264
|
|
| OpuBB |
COG1174 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
2-206 |
1.02e-92 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440787 [Multi-domain] Cd Length: 212 Bit Score: 281.56 E-value: 1.02e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 2 GIFSYMFENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTL 81
Cdd:COG1174 4 SLIEWLADNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRRLAGLVLGVANILQTIPSLALLALLIPLLGIGPA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 82 PSVIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG 161
Cdd:COG1174 84 PAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGIRTAAVQNIGTATLAALIGAG 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2124019877 162 GLGFLVFSGISSVNNGMILAGAIPACILALAIDWVLSQVESLVTP 206
Cdd:COG1174 164 GLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTP 208
|
|
| PBP2_AfProX_like |
cd13607 |
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus ... |
256-517 |
1.57e-91 |
|
Substrate-binding protein ProX of ABC-type osmoregulatory transporter from Archaeoglobus fulgidus and its related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus and its related proteins. AfProX is involved in uptake of compatible solutes such as the trimethylammonium compound glycine betaine and the dimethylammonium compound proline betaine, but the relative substrate preference is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. AfProX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270325 Cd Length: 261 Bit Score: 280.24 E-value: 1.57e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13607 1 TVVIGSKTFTEQYILAEMIAQLLEEA-GYPAEHREGLGGTRVLFEALKSGEIDVYVEYTGTLYAEILKRPETWDPAAVLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKyDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFKDA 415
Cdd:cd13607 80 ELKEALAER-GIVVAGPLGFENTYALAMREDRAEALGIRTISDLLARAPDLRFGFDPEFLDRPDGWPALRRVYGLPFKEV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 416 KGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDTM 495
Cdd:cd13607 159 RGLDHTLAYRALKSGQVDVIDAYTTDARIDAYDLRVLEDDRGAFPPYDAVLLYRADLAERAPKAVAALRRLEGRIDADTM 238
|
250 260
....*....|....*....|..
gi 2124019877 496 RELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13607 239 RALNAQVDLEKRSEAEVAAEFL 260
|
|
| PBP2_YehZ |
cd13611 |
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 ... |
256-518 |
1.57e-88 |
|
Substrate-binding domain YehZ of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein YehZ of Clostridium sticklandii is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. YehZ belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270329 Cd Length: 267 Bit Score: 272.92 E-value: 1.57e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEM-------IEKNTNIkieshlgaGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKH-DPI 327
Cdd:cd13611 1 TITVGSKDFTEQLILGKITVQAlqaagadVTDKTNL--------GGSASARQALENGQVDVYWEYTGTAWITYLGHtEPI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 328 SDEQEVYDTTKEELAKKyDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGT---TLEFLNRQDGLRGV 404
Cdd:cd13611 73 LDPQEQYEAVKDLDAEK-GLVWLDPAPLNNTYALAMREATAEELGITTLSDLALAKLPPGDRTfcvDAEFASRPDGLPPL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 405 QNEYGFTFKDA--KGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDV 482
Cdd:cd13611 152 LEAYGFEFPRAnvRQMDTGLVYTATANGQCDFGEVFTTDGRIKALDLVVLEDDKGFFPAYNAAPVVRTEVLDAHPELAEI 231
|
250 260 270
....*....|....*....|....*....|....*.
gi 2124019877 483 INRMMATLDTDTMRELNYQVDVEHKSPKEVAHDFLV 518
Cdd:cd13611 232 LNPISAKLDNDTMQELNARVDVDGEDPADVARDWLV 267
|
|
| PBP2_Opu_like_2 |
cd13613 |
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 ... |
256-517 |
4.66e-88 |
|
Substrate-binding domain of putative ABC-type osmoprotectant uptake system; the type 2 periplasmic-binding protein fold; This group includes the periplasmic substrate-binding component of a putative ABC transport system that is predicted to be involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. The relative substrate preference of this group is not known. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270331 Cd Length: 264 Bit Score: 271.52 E-value: 4.66e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13613 1 RIIIGSKNFTEQVILGELLAQQIEARTDLKVERRFNLGGTFICHQALLSGAIDAYVEYTGTALTAILKQPPIRDPQRVYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGF-TFKD 414
Cdd:cd13613 81 QVKQLYADRFGLEVMPPLGFENTFAILVRGEDARKLGLKTLSDAAPYTPGWRAGFGYEFLERADGYPGLAKTYGLkFAKT 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 415 AKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDT 494
Cdd:cd13613 161 PRVMDLGLLYRALAQKQVDLIAGNSTDGLIAALDLVILEDDRHYFPPYQAVPVVRQATLAKYPELRTAIAELAGKISAET 240
|
250 260
....*....|....*....|...
gi 2124019877 495 MRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13613 241 MQQMNYQVDGEHRDVAEVAREFL 263
|
|
| PBP2_OpuCC_like |
cd13608 |
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; ... |
256-517 |
3.36e-87 |
|
Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold; This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270326 Cd Length: 265 Bit Score: 269.49 E-value: 3.36e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNTNIK--IESHLGAggTQVLFSAMEKGDLD-AYIDYTGTAYVDILKHDPISDEQE 332
Cdd:cd13608 1 TIRIGSQSTTESQILAEMVKQLIEHYTDLKveLINNLGS--STVQHQAMLNGDANiSAARYTGTDLTGELGMEPIKDPEK 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 333 VYDTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQ-DGLRGVQNEYGFT 411
Cdd:cd13608 79 ALKVVQKEFQKRFDQTWFDSYGFANTYAFMVTKEFAEKYNLKKVSDLKKVADNLKLGVDTSWLNRKgDGYPGFKETYGFD 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 412 FKDAKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLD 491
Cdd:cd13608 159 FGTVYPMQIGLVYDAVASGKMDVVLGYSTDGRIKSYDLVVLEDDKQFFPPYDASPVATNEILKKYPELEEILEKLEGKIS 238
|
250 260
....*....|....*....|....*.
gi 2124019877 492 TDTMRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13608 239 TETMQELNYQVDNDLKEPSVVAKEFL 264
|
|
| PBP2_ProWY |
cd13615 |
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding ... |
256-517 |
2.49e-67 |
|
Substrate-binding domain of ABC-type osmoregulated transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein ProWY of Streptococcus thermophilus is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ProWY belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270333 Cd Length: 262 Bit Score: 218.08 E-value: 2.49e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTqVLFSAMEKGDLDAYIDYTGTAYVDILKHDPISDEQEVYD 335
Cdd:cd13615 1 AIRVGSKDFTENLIVAEIYALALEDA-GYKVKRKPNISSS-VVHQALTSGQIDLYPEYTGTGLLAVLKKEAITDPQKVYA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 336 TTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYG-FTFKD 414
Cdd:cd13615 79 TVKDGYAKKFNLVWLDYAPANDGQGLVIRTSVAKKYGIKTISDLQKNASQIRFASQGEFDQREDGLPGLEKVYGkFSFKS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 415 AKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEHPELQDVINRMMATLDTDT 494
Cdd:cd13615 159 TKVYDNGLKYQVLANDKADITPAYTTEGQLDTSKFTLLKDDKHVWPPYNLAPVVRKDVLKANPKIASALNKVSAKLTTKT 238
|
250 260
....*....|....*....|...
gi 2124019877 495 MRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13615 239 LTQLNAKVDVDKQEYADVAKDFY 261
|
|
| OpuAC |
pfam04069 |
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity ... |
256-517 |
3.33e-66 |
|
Substrate binding domain of ABC-type glycine betaine transport system; Part of a high affinity multicomponent binding-protein-dependent transport system involved in bacterial osmoregulation. This domain is often fused to the permease component of the transporter complex. Family members are often integral membrane proteins or predicted to be attached to the membrane by a lipid anchor. Glycine betaine is involved in protection from high osmolarity environments for example in Bacillus subtilis. The family member OpuBC is closely related, and involved in choline transport. Choline is necessary for the biosynthesis of glycine betaine. L-carnitine is important for osmoregulation in Listeria monocytogenes. Family also contains proteins binding l-proline (ProX), histidine (HisX) and taurine (TauA).
Pssm-ID: 397954 [Multi-domain] Cd Length: 257 Bit Score: 214.88 E-value: 3.33e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIEShLGAGGTQVLFSAMEKGDLDAYID-YTGTAYvdilkhdpisdeqevy 334
Cdd:pfam04069 2 TIVIGSKNWTEQEILANIAAQLLEAL-GYVVEL-VGLGSSAVLFAALASGDIDLYPEeWTGTTY---------------- 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 335 DTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGL------RGVQNEY 408
Cdd:pfam04069 64 EAYKKAVEEKLGLLVLGPLGAGNTYGLAVPKYVAEKPGIKSISDLAKPADDLELGFKGEFIGRPDGWgcmrstEGLLKAY 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 409 GFT-----FKDAKGIDgATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPP-YYGVPLVRQETIEEHPELQDV 482
Cdd:pfam04069 144 GLDkyelvEGSEAAMD-ALIYAAYKRGEPDVVYAWTPDWMIKKYDLVVLEDPKGLFPPaYNVVPVVRKGFAEKHPEVAAF 222
|
250 260 270
....*....|....*....|....*....|....*
gi 2124019877 483 INRMmaTLDTDTMRELNYQVDVEHKSPKEVAHDFL 517
Cdd:pfam04069 223 LNKL--SLDTEDLNELNAQVDVEGKDPEEVAKDWL 255
|
|
| PBP2_OsmF |
cd13616 |
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 ... |
256-517 |
3.49e-60 |
|
Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold; Osmoprotectant binding lipoprotein OsmF of an ABC transporter (YehZYXW) from Escherichia coli is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. OsmF belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270334 Cd Length: 274 Bit Score: 199.48 E-value: 3.49e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGTAYVDILKHDPIS--DEQEV 333
Cdd:cd13616 1 PVVVGSKIDTEGALLGNMIVLALEAH-GFPVEDKTGLGTTPVVRKALLSGEIDLYPEYTGNGAFFFPEADDPVwkDARKG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 334 YDTTKEELAKKYDVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLS-QVAS--SLKAGTTLEFLNRQDGLRGVQNEYGF 410
Cdd:cd13616 80 YETVKELDAKNNGLVWLDPAPANNTWAIAVRRDLAEKNNLKTLADLAaYVNEggAFKLAASAEFVERPDALPAFEKAYGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 411 TFKdakgidgATRYVALSSGD--------------VQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIEEH 476
Cdd:cd13616 160 KLS-------KDQLVILSGGNtaqteqaaaqgtsgVNAAMAYGTDGAIAALGLVVLEDPKGAQPVYAPAPVVRQEVLEAY 232
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 2124019877 477 PELQDVINRMMATLDTDTMRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13616 233 PEIAEILKPVFATLDLKTLQELNARIAVEGESAEDVARDYL 273
|
|
| PBP2_ProX_like |
cd13606 |
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related ... |
256-517 |
5.26e-54 |
|
Bacterial substrate-binding protein ProX of ABC-type osmoregulated transporter and its related proteins; the type 2 periplasmic-binding protein fold; This group includes periplasmic substrate-binding component of ABC transport systems from gram-negative and -positive bacteria that are involved in uptake of osmoprotectants (also termed compatible solutes) such as betaine, choline, proline betaine, carnitine, and L-proline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.
Pssm-ID: 270324 Cd Length: 260 Bit Score: 182.77 E-value: 5.26e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 256 TIRIGSKQFTEQLVLGNMLGEMIEKNtNIKIESHLGAGGTQVLFSAMEKGDLDAYIDYTGT--AYVDilKHDPISDEQEV 333
Cdd:cd13606 1 TVVVGSADFPESEILAEIYAQALEAA-GVKVTRKLNIGSREVYLPALEDGSIDLVPEYTGNllQYLD--KDATATDPEEV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 334 YDTTKEELAKKydVALLAAAPFSNTYTLAVDPAVAQAYNLHTMSDLSQVASSLKAGTTLEFLNRQDGLRGVQNEYGFTFK 413
Cdd:cd13606 78 YAALKAALPEG--LEVLDPSPAEDKDALVVTKETAEKYGLKSIADLAPVAGELTLGGPPEFKTRPYGLPGLKEVYGVTFK 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 414 --DAKGIDGATRYVALSSGDVQVVDAFSTDGLLKKYNLTVLADDKGFFPPYYGVPLVRQETIeeHPELQDVINRMMATLD 491
Cdd:cd13606 156 efKPLDAGGPLTVKALKDGTVQVANIFTTDPAIADNGLVVLEDPKNLFPAQNVVPLVRKAKL--DDKAADALNAVSAKLT 233
|
250 260
....*....|....*....|....*.
gi 2124019877 492 TDTMRELNYQVDVEHKSPKEVAHDFL 517
Cdd:cd13606 234 TEDLTELNKQVVGDKADPADVAKEWL 259
|
|
| TauC |
COG0600 |
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ... |
3-206 |
4.92e-37 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440365 [Multi-domain] Cd Length: 254 Bit Score: 137.20 E-value: 4.92e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 3 IFSYMFENIDQimRLLLEHI----QLTAIAVGLAILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGI 78
Cdd:COG0600 46 VLAALVELLAS--GELWEHLlaslLRVLLGFALAALLGVPLGLLLGLSRLLRRLLDPLLVFLRPIPPLALAPLLILWFGI 123
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 79 GTLPSVIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVgLMTIAA-F 157
Cdd:COG0600 124 GEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW-IGLVVAeL 202
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 2124019877 158 IGAG-GLGFLVFSGISSVNNGMILAGAIPACILALAIDWVLSQVESLVTP 206
Cdd:COG0600 203 LGASsGLGYLILDARQLLDTDLVFAAILVIGLLGLLLDLLLRLLERRLLR 252
|
|
| ProW |
COG4176 |
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ... |
24-193 |
8.95e-34 |
|
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 443335 Cd Length: 275 Bit Score: 129.06 E-value: 8.95e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 24 LTAIAVGLAILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPSVIVVFLYSLLPIVKNTYIGI 103
Cdd:COG4176 98 LVLVAVLIALLIGIPLGILAARSDRVSRIVRPVLDFMQTMPAFVYLIPAVMLFGIGKVPGVIATVIFALPPAIRLTNLGI 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 104 SQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAGGLGFLVFSGISSVNNGM-ILAG 182
Cdd:COG4176 178 RQVPKELVEAADAFGATPWQLLFKVQLPLALPTIMAGVNQTIMLALSMVVIASMIGAGGLGQEVLRALQRLDIGLgFEAG 257
|
170
....*....|.
gi 2124019877 183 aipACILALAI 193
Cdd:COG4176 258 ---LAIVILAI 265
|
|
| PRK10952 |
PRK10952 |
proline/glycine betaine ABC transporter permease ProW; |
33-194 |
8.53e-27 |
|
proline/glycine betaine ABC transporter permease ProW;
Pssm-ID: 236805 Cd Length: 355 Bit Score: 111.34 E-value: 8.53e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 33 ILVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPSVIVVFLYSLLPIVKNTYIGISQISPGTIE 112
Cdd:PRK10952 161 IVIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIVRLTILGINQVPADLIE 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 113 AARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAGGLGFLVFSGISSVNNGMILAGAIPACILALA 192
Cdd:PRK10952 241 ASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAII 320
|
..
gi 2124019877 193 ID 194
Cdd:PRK10952 321 LD 322
|
|
| TM_PBP2 |
cd06261 |
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ... |
18-193 |
5.11e-19 |
|
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.
Pssm-ID: 119394 [Multi-domain] Cd Length: 190 Bit Score: 85.02 E-value: 5.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 18 LLEHIQLTAIAVGLAILVGLPLGILI-SYVKPLNKPVMGATNLIQAVPSMALL---------GFAIPLLGIGTLPSVIVV 87
Cdd:cd06261 1 LLNTLLLALIATLLALVLGLLLGIILaRKRGKLDRLLRRIIDLLLSLPSLVLGlllvllfgvLLGWGILPGLGLPALILA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 88 FLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG---GLG 164
Cdd:cd06261 81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGeapGPG 160
|
170 180
....*....|....*....|....*....
gi 2124019877 165 FLVFSGISSVNNGMILAGAIPACILALAI 193
Cdd:cd06261 161 TGLLLIFAILFPGDLGVAAAVALILLLLS 189
|
|
| MetP |
COG2011 |
ABC-type methionine transport system, permease component [Amino acid transport and metabolism]; ... |
7-166 |
7.13e-19 |
|
ABC-type methionine transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 441614 Cd Length: 220 Bit Score: 85.49 E-value: 7.13e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 7 MFENIDQIMRLLL----EHIQLTAIAVGLAILVGLPLGIL--------ISYVKPLNKPVMGATNLIQAVPSMALLGFAIP 74
Cdd:COG2011 1 MLTMWSELWPLLLqatgETLYMVGVSTLIAVLLGLPLGVLlvltrpggLLPNPVLYRVLGVIVNIFRSIPFIILLVALIP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 75 L----LG--IGTLP-----SVIVVFLYSLLpiVKNTyigISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRI 143
Cdd:COG2011 81 LtrliVGtsIGTTAaivplTIAAIPFFARL--VENA---LREVDPGVIEAAQAMGASPWQIIFKVLLPEALPSLILGLTV 155
|
170 180
....*....|....*....|...
gi 2124019877 144 SAVTAVGLMTIAAFIGAGGLGFL 166
Cdd:COG2011 156 TLISLIGYSAMAGAVGGGGLGDL 178
|
|
| BPD_transp_1 |
pfam00528 |
Binding-protein-dependent transport system inner membrane component; The alignments cover the ... |
36-193 |
1.16e-18 |
|
Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.
Pssm-ID: 334128 [Multi-domain] Cd Length: 183 Bit Score: 83.89 E-value: 1.16e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 36 GLPLGILI--SYVKPLNKPVMGATNLIQAVPSMALLGFAIPL-----LGIGTLPSVIVVFLYSLLPIVKNTYIGISQISP 108
Cdd:pfam00528 1 GIPLGIIAalRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIailsiLGHGILPAIILALLGWAGYARLIRRAALRSLPS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 109 GTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAG-GLGFLVFSGISSVNNGMILAGAIPAC 187
Cdd:pfam00528 81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWpGLGLLLIEAILGYDYPEIQGPVLAAA 160
|
....*.
gi 2124019877 188 ILALAI 193
Cdd:pfam00528 161 LILLLL 166
|
|
| PhnE |
COG3639 |
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ... |
8-200 |
9.37e-17 |
|
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 442856 [Multi-domain] Cd Length: 244 Bit Score: 79.74 E-value: 9.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 8 FENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGIL----ISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPS 83
Cdd:COG3639 43 WSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLaarnLAPNPWVRLLARRLLNVLRAIPELVWALIFVAAVGLGPFAG 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 84 VIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMA--------GVRISAVtaVGlmtia 155
Cdd:COG3639 123 VLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASRLQVIRYGVLPQVLPQFLSytlyrfeiNIRAATV--LG----- 195
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2124019877 156 aFIGAGGLGFLVFSGISSVNNGMilAGAIPACILAL--AIDWVLSQV 200
Cdd:COG3639 196 -LVGAGGIGLLLNEAIRLFQYDE--VAAILLVILVLvlLIDLLSARL 239
|
|
| PRK10160 |
PRK10160 |
taurine ABC transporter permease TauC; |
24-206 |
4.58e-14 |
|
taurine ABC transporter permease TauC;
Pssm-ID: 182276 Cd Length: 275 Bit Score: 72.51 E-value: 4.58e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 24 LTAIAVGL--AILVGLPLGILISyvkpLNKPVMGATN----LIQAVPSMALLGFAIPLLGIGTLPSVIVVFLYSLLPIVK 97
Cdd:PRK10160 84 LTRIVLALlaAVVIGIPVGIAMG----LSPTVRGILDplieLYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAM 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 98 NTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISavTAVGLMTIAA--FIGAG-GLGFLVFSGISSV 174
Cdd:PRK10160 160 SALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIG--LGVGWSTLVAaeLIAATrGLGFMVQSAGEFL 237
|
170 180 190
....*....|....*....|....*....|..
gi 2124019877 175 NNGMILAGAIPACILALAIDWVLSQVESLVTP 206
Cdd:PRK10160 238 ATDVVLAGIAVIAIIAFLLELGLRALQRRLTP 269
|
|
| PhnE |
TIGR01097 |
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound ... |
8-196 |
3.78e-13 |
|
phosphonate ABC transporter, permease protein PhnE; Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions]
Pssm-ID: 273441 [Multi-domain] Cd Length: 250 Bit Score: 69.49 E-value: 3.78e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 8 FENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGIL----ISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPS 83
Cdd:TIGR01097 50 WSYLPRILKALLETLAMAILGTVLAAVLAVPLALLaarnITPSPWLYGLARLLLNFLRAIPELVWALIFVAAVGLGPFAG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 84 VIVVFLYSLLPIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMA--------GVRISAVtaVGlmtia 155
Cdd:TIGR01097 130 VLALAFHTVGFLGKLFAEAIEEVDPGPVEALRATGASKLQVIRYGVLPQVLPQFLSytlyrfeiNVRAAAV--LG----- 202
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 2124019877 156 aFIGAGGLGFLVFSGISSVN---NGMILAGAIpacILALAIDWV 196
Cdd:TIGR01097 203 -LVGAGGIGLELDTAIGLFDydeVSAIILVIL---VVVVIIDLI 242
|
|
| HisM |
COG0765 |
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ... |
1-131 |
5.08e-13 |
|
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];
Pssm-ID: 440528 [Multi-domain] Cd Length: 218 Bit Score: 68.18 E-value: 5.08e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 1 MGIFSYMFENIDQIMRLLLEHIQLTAIAVGLAILVGLPLGIL-ISYVKPLNKPVMGATNLIQAVPSMALL---GFAIPLL 76
Cdd:COG0765 2 FFDFSVLLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALArLSPNPVLRWLATAYVEFFRGTPLLVQLffiYFGLPLL 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2124019877 77 GI--GTLPSVIVVF-LYSllpivkNTYI------GISQISPGTIEAARGIGLTRQQILWKVQLP 131
Cdd:COG0765 82 GIdlSPFVAAVIALtLNS------AAYLaeivraGIQSVPKGQWEAARALGLSRWQTMRRIILP 139
|
|
| PRK10782 |
PRK10782 |
D-methionine ABC transporter permease MetI; |
11-164 |
1.58e-12 |
|
D-methionine ABC transporter permease MetI;
Pssm-ID: 182726 Cd Length: 217 Bit Score: 66.68 E-value: 1.58e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 11 IDQIMRLLLEHIQLTAIAVGLAILVGLPLGILISYVKP--------LNKPVMGATNLIQAVPSMALLGFAIPL--LGIGT 80
Cdd:PRK10782 6 MWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPgqiianakLYRTLSALVNIFRSIPFIILLVWMIPFtrVIVGT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 81 ---LPSVIVVFLYSLLP----IVKNTYIgisQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMT 153
Cdd:PRK10782 86 sigLQAAIVPLTVGAAPfiarMVENALL---EIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGYSA 162
|
170
....*....|.
gi 2124019877 154 IAAFIGAGGLG 164
Cdd:PRK10782 163 MGGAVGAGGLG 173
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
22-193 |
1.83e-12 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 69.42 E-value: 1.83e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 22 IQLTAIAVGLAILVGLPLGILIS-YVKPLNKPVMGATNLIQAVPSMAL-LGFAIPLLGI------GTLPSVIVVFLYSLL 93
Cdd:COG1178 344 LLLALLAALLAVLLALLLAYLVRrRRGRLARLLDRLAMLPYAVPGIVLgLGLLLLFNRPlplllyGTLAILVLAYVVRFL 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 94 PI-VKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAFIGAGG---LGFLVFS 169
Cdd:COG1178 424 PFaLRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGfetLAVLIYQ 503
|
170 180
....*....|....*....|....
gi 2124019877 170 GISSvnnGMILAGAIPACILALAI 193
Cdd:COG1178 504 LASS---GRYGEAAALALLLVLVS 524
|
|
| ssuC |
PRK11365 |
aliphatic sulfonate ABC transporter permease SsuC; |
18-166 |
6.43e-12 |
|
aliphatic sulfonate ABC transporter permease SsuC;
Pssm-ID: 183100 Cd Length: 263 Bit Score: 66.11 E-value: 6.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 18 LLEHIQLTA--IAVGLAI--LVGLPLGILISYVKPLNKPVMGATNLIQAVPSMALLGFAIPLLGIGTLPSVIVVFLYSLL 93
Cdd:PRK11365 58 LWQHLAISSwrALIGFSIggSLGLILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLF 137
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2124019877 94 PIVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRIsavtAVGLM----TIAAFIGA-GGLGFL 166
Cdd:PRK11365 138 PIYINTWHGIRNIDRGLVEMARSYGLSGIPLFIHVILPGALPSIMVGVRF----ALGLMwltlIVAETISAnSGIGYL 211
|
|
| PotB |
COG1176 |
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ... |
22-161 |
3.09e-09 |
|
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];
Pssm-ID: 440789 [Multi-domain] Cd Length: 287 Bit Score: 58.24 E-value: 3.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 22 IQLTAIAVGLAILVGLPLGILISYVKPLNKPVMGA-------TNLI-----------------QAVPSMALLGFAIPLLG 77
Cdd:COG1176 73 LWIALLTTLICLLLGYPIAYFLARAPPRWRNLLLLlvilpfwTSFLvrtyawivllgrngllnSLLLALGLIDEPLRLLY 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 78 igTLPSVIVVFLYSLLP-IVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAA 156
Cdd:COG1176 153 --TEFAVVIGLVYVYLPfMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPA 230
|
....*
gi 2124019877 157 FIGAG 161
Cdd:COG1176 231 LLGGG 235
|
|
| PotC |
COG1177 |
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ... |
4-197 |
2.40e-08 |
|
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];
Pssm-ID: 440790 [Multi-domain] Cd Length: 262 Bit Score: 55.12 E-value: 2.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 4 FSYMFENiDQIMRLLLEHIQLTAIAVGLAILVGLPLGILISYVK-PLNKPVMGATNLIQAVPS----MALLGFAIPLLGI 78
Cdd:COG1177 50 YAELFSD-PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRfRGRRLLLALLLLPLVVPGivlgVALLLLFSALGLS 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 79 GTLPSVIVVFLYSLLPIV-KNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTIAAF 157
Cdd:COG1177 129 GGLWGLILAHVVFTLPFVvLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLF 208
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2124019877 158 IGAGG---LGFLVFSGISSVNNGMILAGA----IPACILALAIDWVL 197
Cdd:COG1177 209 LAGPGvttLPVYIYSMIRRGISPEINALStlliLLSLLLLLLAERLR 255
|
|
| FbpB |
COG1178 |
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; |
71-242 |
1.15e-06 |
|
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440791 [Multi-domain] Cd Length: 538 Bit Score: 51.32 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 71 FAIPLLGIGTLPSVIVVFLYSLLPIV-KNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAV 149
Cdd:COG1178 129 FGLEPPDIYGLGGIILVLVLFNYPYVyLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCL 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 150 GLMTIAAFIGAgglGFLVFS--------GISSVNNGMILAGA-IPACILALAIDWVLSQVESLVTPVSlqpellKTRSTL 220
Cdd:COG1178 209 ADFGTPLVLGG---GYTTLTtaiyqawlGDFDLGAAAALALVlLLLVLLLLLLERRLRRRRRYATVGG------RARRPR 279
|
170 180
....*....|....*....|..
gi 2124019877 221 TAKRRRQKWSVGVVVALLVFMF 242
Cdd:COG1178 280 RVKLGRWRWLALALCLLLVLLG 301
|
|
| UgpE |
COG0395 |
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ... |
4-184 |
8.44e-06 |
|
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];
Pssm-ID: 440164 [Multi-domain] Cd Length: 282 Bit Score: 47.40 E-value: 8.44e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 4 FSYMFENIDqIMRLLLEHIQLTAIAVGLAILVGLPLGILISYVK-PLNKPVMGATNLIQAVPSMALLgfaIPL------L 76
Cdd:COG0395 63 YRAAFTDGP-FGRYLLNSLIVAVVSTVLSLLLSSLAAYALARFRfRGRKLLFLLILATLMIPGQVLL---IPLyllfrqL 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 77 G-IGTLPSVIVVFLYSLLPIvkNTYI---GISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTA---- 148
Cdd:COG0395 139 GlLNTYWGLILPYLAFGLPF--GIFLlrqFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIFTFIGAwndf 216
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 2124019877 149 ---------VGLMTIAAFIGAgglgflvFSGISSVNNGMILAGAI 184
Cdd:COG0395 217 lwplilltsPDLRTLPVGLAS-------FQGQYGTDWGLLMAAAV 254
|
|
| DppB |
COG0601 |
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ... |
22-173 |
4.09e-05 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440366 [Multi-domain] Cd Length: 314 Bit Score: 45.44 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 22 IQLTAIAVGLAILVGLPLGIlISYVKP---LNKPVMGATNLIQAVPS-----MALLGFAI-----PLLGIGTLPSVIVVF 88
Cdd:COG0601 99 LELALLALLLALLIGIPLGI-LAALRRgswLDRLITVLALLGISIPSfwlglLLILLFAVklgwlPVSGRVSPWEDFLDA 177
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 89 LYSL-LPIVKNTYIGISQISPGT------------IEAARGIGLTRQQILWKVQLPLTLpmlmagvrISAVTAVGLMTIA 155
Cdd:COG0601 178 LRHLiLPALTLALGSLAGIARLTrssmlevlgqdyVRTARAKGLSERRVLLRHALRNAL--------IPVVTVLGLQLGG 249
|
170 180
....*....|....*....|....*..
gi 2124019877 156 AFIGA---------GGLGFLVFSGISS 173
Cdd:COG0601 250 LLGGAvvvetvfswPGLGRLLVDAILN 276
|
|
| potB |
PRK09497 |
spermidine/putrescine ABC transporter membrane protein; Reviewed |
18-161 |
7.99e-05 |
|
spermidine/putrescine ABC transporter membrane protein; Reviewed
Pssm-ID: 181910 Cd Length: 285 Bit Score: 44.68 E-value: 7.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 18 LLEHIQLTAIAVGLAILVGLPLGILISYVKPLNKPVM--------GATNLI-----------QAVPSMALLGFAI---PL 75
Cdd:PRK09497 65 LLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLlfllivpfWTNSLIriyglkiflstKGYLNEFLLWLGVidtPI 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 76 LGIGTLPSVIVVFLYSLLP-IVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVGLMTI 154
Cdd:PRK09497 145 RIMFTESAVIIGLVYILLPfMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYV 224
|
....*..
gi 2124019877 155 AAFIGAG 161
Cdd:PRK09497 225 SDLLGGA 231
|
|
| TauA |
COG0715 |
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion ... |
253-491 |
1.83e-04 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [Inorganic ion transport and metabolism];
Pssm-ID: 440479 [Multi-domain] Cd Length: 297 Bit Score: 43.46 E-value: 1.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 253 DPNTIRIGSKQFTEQLVLGNMLGEMIEKNTNIKIESHLGAGGTQVLfSAMEKGDLDAYIDYTGTAYVDIlkhdpisdeqe 332
Cdd:COG0715 20 EKVTLRLGWLPNTDHAPLYVAKEKGYFKKEGLDVELVEFAGGAAAL-EALAAGQADFGVAGAPPALAAR----------- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 333 vydttkeelAKKYDVALLAAAPFSNTYTLAVDPAvaqaYNLHTMSDLS--QVASSlkAGTTLEFLnrqdgLRGVQNEYGF 410
Cdd:COG0715 88 ---------AKGAPVKAVAALSQSGGNALVVRKD----SGIKSLADLKgkKVAVP--GGSTSHYL-----LRALLAKAGL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 411 TFKDAK--GIDGATRYVALSSGDVQVVDAFSTDG--LLKKYNLTVLADDKGFFPPYYGVPLV-RQETIEEHPE-LQDVIN 484
Cdd:COG0715 148 DPKDVEivNLPPPDAVAALLAGQVDAAVVWEPFEsqAEKKGGGRVLADSADLVPGYPGDVLVaSEDFLEENPEaVKAFLR 227
|
....*..
gi 2124019877 485 RMMATLD 491
Cdd:COG0715 228 ALLKAWA 234
|
|
| MalG |
COG3833 |
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ... |
27-160 |
2.12e-03 |
|
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];
Pssm-ID: 443045 [Multi-domain] Cd Length: 282 Bit Score: 40.13 E-value: 2.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 27 IAVGLAILvGLPLGILISYVK-----PLNKPVMGATNLIQAVPSMALLgFAIPLL-----GIGTLPSVIVVFLYSLLP-- 94
Cdd:COG3833 81 VAVVTAII-SVFLAALAAYAFsrfrfKGRKAGLLALLLLQMFPAFLAL-VALYLLlsalgLLNTLLGLILVYLGGAIPfn 158
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2124019877 95 --IVKNTYIGIsqisPGTI-EAARGIGLTRQQILWKVQLPLTLPMLmagvrisAVTAvglmtIAAFIGA 160
Cdd:COG3833 159 twLMKGYFDTI----PKELdEAAKIDGASHFQIFFRIILPLAKPIL-------AVVA-----LLSFIGP 211
|
|
| CysU |
COG0555 |
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ... |
25-150 |
4.17e-03 |
|
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];
Pssm-ID: 440321 [Multi-domain] Cd Length: 268 Bit Score: 38.96 E-value: 4.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2124019877 25 TAIAVGLAILVGLPLG-ILISYVKPLNKPVMGATNLIQAVP-------------SMALLGFAIPLLGI---GTLPSVIVV 87
Cdd:COG0555 63 ALIAALINLVFGLPLAwVLVRYRFPGKRLVDALVDLPFALPtavagiallllfgPNGWLGQLLAPLGIkvaFTPLGIVLA 142
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2124019877 88 FLYSLLP-IVKNTYIGISQISPGTIEAARGIGLTRQQILWKVQLPLTLPMLMAGVRISAVTAVG 150
Cdd:COG0555 143 QTFVSLPfVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARALG 206
|
|
| |
