|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-470 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 843.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 1 MTPDKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKF 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 81 AEGKVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVN 160
Cdd:PRK06247 81 ADGKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAFLMAKIEKPSAVTQLREIAELSDAIMVA 240
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 241 RGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPIE 320
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 321 AVQMMSKIIRQVENGPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLTP 400
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 401 NLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIETL 470
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYI 470
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 724.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 3 PDKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAE 82
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 83 GKVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELI---GDKAFLMAKIEKPSAVTQLREIAELSDAIMV 239
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLeeaGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 240 ARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPI 319
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 320 EAVQMMSKIIRQVENGPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLT 399
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2100171583 400 PNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIETL 470
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 521.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 VQLHRGQALRLDLDPTP--GDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKgeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDK----AFLMAKIEKPSAVTQLREIAELSDAIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgakdVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 239 VARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 319 IEAVQMMSKIIRQVENGPDYQTQLDVSRPKA--EATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPIL 396
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKNSDpkPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2100171583 397 NLTPNLQTARRLTVAWGVHSV-VNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRI 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFlVDEEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-470 |
1.61e-162 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 467.95 E-value: 1.61e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEG- 83
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 84 KVQLHRGQALRLDLDPTP--GDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADA-IDTTVLNGGELSDRKGVN 160
Cdd:cd00288 82 DISLKAGDKFLVTTDPAAkkGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF---LMAKIEKPSAVTQLREIAELSDAI 237
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKdikIIAKIENQEGVNNFDEILEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 238 MVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEY 317
Cdd:cd00288 242 MVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 318 PIEAVQMMSKIIRQVENGPDYQTQLDVSRPKAE--ATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPI 395
Cdd:cd00288 322 PVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrpTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAPI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 396 LNLTPNLQTARRLTVAWGVHSVVNDRLRQ-----VDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQpGSTNSLRIETL 470
Cdd:cd00288 402 IAVTRNEQTARQLHLYRGVYPVLFEEPKPgwqedTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGS-GSTNTMRILTV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-338 |
3.93e-129 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 377.86 E-value: 3.93e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 --VQLHRGQALRLDLDP---TPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADA-IDTTVLNGGELSDRKG 158
Cdd:pfam00224 82 kdIELKAGDEMIVSTDAkykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 159 VNVPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF---LMAKIEKPSAVTQLREIAELSD 235
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKniqIIAKIENQEGVNNFDEILEATD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 236 AIMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASG 315
Cdd:pfam00224 242 GIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 321
|
330 340
....*....|....*....|...
gi 2100171583 316 EYPIEAVQMMSKIIRQVENGPDY 338
Cdd:pfam00224 322 NYPVEAVRMMHEICLEAEKALPH 344
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK06247 |
PRK06247 |
pyruvate kinase; Provisional |
1-470 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 180487 [Multi-domain] Cd Length: 476 Bit Score: 843.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 1 MTPDKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKF 80
Cdd:PRK06247 1 MKRNRRVKILATLGPASSSEDMIRKLVEAGADVFRLNFSHGDHDDHRELYKRIREVEDETGRPIGILADLQGPKLRLGRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 81 AEGKVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVN 160
Cdd:PRK06247 81 ADGKVQLANGQTFRLDVDDAPGDHDRVSLPHPEIAAALKPGDRLLVDDGKVRLVVEACDGDDVVCRVVEGGPVSDRKGVS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAFLMAKIEKPSAVTQLREIAELSDAIMVA 240
Cdd:PRK06247 161 LPGTVLSVSALTEKDRADLEFALELGVDWVALSFVQRPEDVEEVRKIIGGRVPVMAKIEKPQAIDRLEAIVEASDAIMVA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 241 RGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPIE 320
Cdd:PRK06247 241 RGDLGVEVPLEQVPLIQKRIIRAARRAGKPVVVATQMLESMIENPVPTRAEVSDVATAVLDGADAVMLSAETASGKYPVE 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 321 AVQMMSKIIRQVENGPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLTP 400
Cdd:PRK06247 321 AVRTMARIIRQVERDPTYPPLIHAQRPQPEATKRDAISYAARDIAERLDLAALVAYTSSGDTALRAARERPPLPILALTP 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 401 NLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIETL 470
Cdd:PRK06247 401 NPETARRLALTWGVHCVVVDDARDTDDMVRRADRIALAEGFYKRGDRVVIVAGVPPGTPGSTNMLRIAYI 470
|
|
| PykF |
COG0469 |
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the ... |
3-470 |
0e+00 |
|
Pyruvate kinase [Carbohydrate transport and metabolism]; Pyruvate kinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 440237 [Multi-domain] Cd Length: 471 Bit Score: 724.90 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 3 PDKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAE 82
Cdd:COG0469 1 MMRRTKIVATLGPASDSPEVLRKLIEAGMDVARLNFSHGDHEEHRERIELIREAAKELGRPVAILLDLQGPKIRTGKFKE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 83 GKVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:COG0469 81 GPVELKKGDTFTLTTDDVEGDAERVSVTYPELPEDVKPGDRILLDDGKIELRVEEVEGDEVVCEVVNGGVLSSRKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELI---GDKAFLMAKIEKPSAVTQLREIAELSDAIMV 239
Cdd:COG0469 161 GVGLSLPALTEKDREDLKFALELGVDFIALSFVRSAEDVLEARELLeeaGGRAPIIAKIEKPEAVENLDEIIEASDGIMV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 240 ARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPI 319
Cdd:COG0469 241 ARGDLGVEIPLEEVPLIQKRIIRKARRAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAVGKYPV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 320 EAVQMMSKIIRQVENGPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLT 399
Cdd:COG0469 321 EAVETMARIAEEAEKSLDYRRILDRLRDEPERTITDAIARAAVELAEDLGAKAIVAFTESGSTARRISRYRPKVPILALT 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2100171583 400 PNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIETL 470
Cdd:COG0469 401 PNERTARRLALVWGVYPVLVDDVESTDEMIEEAVEALLEEGLVKPGDLVVITAGVPVGVPGTTNTLKVHRV 471
|
|
| PRK05826 |
PRK05826 |
pyruvate kinase; Provisional |
3-460 |
0e+00 |
|
pyruvate kinase; Provisional
Pssm-ID: 235619 [Multi-domain] Cd Length: 465 Bit Score: 541.28 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 3 PDKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAE 82
Cdd:PRK05826 2 MLRRTKIVATLGPASDSPENLEKLIEAGVNVVRLNFSHGSHEEHGKRAALVREIAAKLGRPVAILLDLKGPKIRVGKFKE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 83 GKVQLHRGQALRLDLDPT-PGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNV 161
Cdd:PRK05826 82 GKITLKTGDKFTLDTDQKeEGDKERVGVDYKGLPKDVKPGDILLLDDGKLQLKVVEVDGDEVETEVKNGGPLSNNKGINI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 162 PQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELI----GDKAFLMAKIEKPSAVTQLREIAELSDAI 237
Cdd:PRK05826 162 PGGGLSLPALTEKDKADIKFAAEQGVDYIAVSFVRSAEDVEEARRLLreagCPHAKIIAKIERAEAVDNIDEIIEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 238 MVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEY 317
Cdd:PRK05826 242 MVARGDLGVEIPDEEVPGLQKKIIRKAREAGKPVITATQMLESMIENPRPTRAEVSDVANAVLDGTDAVMLSGETAAGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 318 PIEAVQMMSKIIRQVENGPDYQTQLDVSrPKAEATVSDAISCAIRRISNVLP-VAVLVNYSESGTSSLRAARERPTVPIL 396
Cdd:PRK05826 322 PVEAVEAMARICKGAEKEFSINLSKHRL-DRQFDRIDEAIAMSAMYAANHLKgVKAIVALTESGRTARLISRFRPGAPIF 400
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2100171583 397 NLTPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPG 460
Cdd:PRK05826 401 AVTRDEKTQRRLALYRGVYPVLFDSAADTDDAAEEALRLLLEKGLVESGDLVVVTSGDPMGTAG 464
|
|
| pyruv_kin |
TIGR01064 |
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of ... |
5-467 |
0e+00 |
|
pyruvate kinase; This enzyme is a homotetramer. Some forms are active only in the presence of fructose-1,6-bisphosphate or similar phosphorylated sugars. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 273424 [Multi-domain] Cd Length: 472 Bit Score: 521.84 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:TIGR01064 1 RRTKIVCTIGPATNSPEMLKKLLDAGMNVARLNFSHGSHEEHGKRIENVREAAEKLGRPVAILLDTKGPEIRTGEIKGGE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 VQLHRGQALRLDLDPTP--GDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:TIGR01064 81 VKLKKGDKVIITTDDIKgeGDEEKVYVDYKGLTKDVVEGDKILVDDGKISLVVVSVEGDKVICEVLNGGTLKSKKGVNLP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDK----AFLMAKIEKPSAVTQLREIAELSDAIM 238
Cdd:TIGR01064 161 GADVDLPALSEKDKKDLKFGVEQGVDMVAASFVRTAEDVLEVREVLGEKgakdVKIIAKIENQEGVDNIDEIAEASDGIM 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 239 VARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYP 318
Cdd:TIGR01064 241 VARGDLGVEIPAEEVPIAQKKMIRKCNRAGKPVITATQMLDSMIKNPRPTRAEVSDVANAVLDGTDAVMLSGETAKGKYP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 319 IEAVQMMSKIIRQVENGPDYQTQLDVSRPKA--EATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPIL 396
Cdd:TIGR01064 321 VEAVQMMAKIAKEAEKALAYLTNFNDRKNSDpkPSTITEAIALSAVEAAEKLDAKAIVVLTESGRTARLLSKYRPNAPII 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 2100171583 397 NLTPNLQTARRLTVAWGVHSV-VNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRI 467
Cdd:TIGR01064 401 AVTPNERVARQLALYWGVFPFlVDEEPSDTDARVNKALELLKEKGIVKKGDLVVVIQGGPIGGEGGTNTIRV 472
|
|
| PRK06354 |
PRK06354 |
pyruvate kinase; Provisional |
5-469 |
2.95e-176 |
|
pyruvate kinase; Provisional
Pssm-ID: 235784 [Multi-domain] Cd Length: 590 Bit Score: 506.77 E-value: 2.95e-176
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:PRK06354 8 RRTKIVATIGPASESPEKLRQLIEAGATTARLNFSHGDHEEHGARIKNIREASKKLGKTVGILQDLQGPKIRLGRFEDGP 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 VQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRV--VTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:PRK06354 88 IELKTGDEFILTSREVLGTQEKFSVTYDGLADEVPVGSRILLDDGLIELEVeeVDKADGELHCKVLVGGVLSNKKGVNFP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF----LMAKIEKPSAVTQLREIAELSDAIM 238
Cdd:PRK06354 168 GVSLSLPAITEKDREDLIFGLEQGVDWIALSFVRNPSDVLEIRELIEEHNGkhipIIAKIEKQEAIDNIDAILELCDGLM 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 239 VARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYP 318
Cdd:PRK06354 248 VARGDLGVEIPAEEVPLLQKRLIKKANRLGKPVITATQMLDSMQRNPRPTRAEASDVANAILDGTDAVMLSNETAAGDYP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 319 IEAVQMMSKIIRQVENGPDYQTQLDvSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNL 398
Cdd:PRK06354 328 VEAVQTMATIAVRIEKDLPYRDILS-KRPEFTTTITNAISQAVSHIALQLDAAAIVTLTKSGATARNVSKYRPKTPILAV 406
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 2100171583 399 TPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIET 469
Cdd:PRK06354 407 TPNESVARRLQLVWGVTPLLVLDAPSTDETFDAAINVAQESGLLKQGDLVVITAGTLVGESGSTDLMKVHV 477
|
|
| Pyruvate_Kinase |
cd00288 |
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of ... |
5-470 |
1.61e-162 |
|
Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low affinity T state. PK exists as several different isozymes, depending on organism and tissue type. In mammals, there are four PK isozymes: R, found in red blood cells, L, found in liver, M1, found in skeletal muscle, and M2, found in kidney, adipose tissue, and lung. PK forms a homotetramer, with each subunit containing three domains. The T state to R state transition of PK is more complex than in most allosteric enzymes, involving a concerted rotation of all 3 domains of each monomer in the homotetramer.
Pssm-ID: 238178 [Multi-domain] Cd Length: 480 Bit Score: 467.95 E-value: 1.61e-162
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEG- 83
Cdd:cd00288 2 RRTKIVCTIGPATDSVENLKKLIKAGMNVARMNFSHGSHEYHQSRIDNVREAAEKTGGPVAIALDTKGPEIRTGLFKGGk 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 84 KVQLHRGQALRLDLDPTP--GDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADA-IDTTVLNGGELSDRKGVN 160
Cdd:cd00288 82 DISLKAGDKFLVTTDPAAkkGTKEKIYVDYKNLTKDVSPGNTILVDDGLLSLKVLSKDDDKtLVCEVLNGGVLGSRKGVN 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF---LMAKIEKPSAVTQLREIAELSDAI 237
Cdd:cd00288 162 LPGTDVDLPALSEKDKADLRFGVEQGVDMIFASFVRKASDVLEIREVLGEKGKdikIIAKIENQEGVNNFDEILEASDGI 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 238 MVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEY 317
Cdd:cd00288 242 MVARGDLGVEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKGKY 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 318 PIEAVQMMSKIIRQVENGPDYQTQLDVSRPKAE--ATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPI 395
Cdd:cd00288 322 PVEAVKAMARICLEAEKALSHRVLFNEMRRLTPrpTSTTEAVAMSAVRAAFELGAKAIVVLTTSGRTARLVSKYRPNAPI 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 396 LNLTPNLQTARRLTVAWGVHSVVNDRLRQ-----VDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQpGSTNSLRIETL 470
Cdd:cd00288 402 IAVTRNEQTARQLHLYRGVYPVLFEEPKPgwqedTDARLKAAVNVAKEKGLLKKGDLVVVVQGWPVGS-GSTNTMRILTV 480
|
|
| PK |
pfam00224 |
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain ... |
5-338 |
3.93e-129 |
|
Pyruvate kinase, barrel domain; This domain of the is actually a small beta-barrel domain nested within a larger TIM barrel. The active site is found in a cleft between the two domains.
Pssm-ID: 395168 [Multi-domain] Cd Length: 348 Bit Score: 377.86 E-value: 3.93e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:pfam00224 2 RRTKIVCTIGPASNSVENLEKLIEAGANVARMNFSHGSHEYHQSRIDNVREAEEKTGGTVAIALDTKGPEIRTGNTKDGK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 --VQLHRGQALRLDLDP---TPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADA-IDTTVLNGGELSDRKG 158
Cdd:pfam00224 82 kdIELKAGDEMIVSTDAkykGACDDEMIYVDYKNIVKDVSVGGTILVDDGLLSLKVLSKDDDKtLVVEVLNGGVIGSRKG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 159 VNVPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF---LMAKIEKPSAVTQLREIAELSD 235
Cdd:pfam00224 162 VNLPGTDVDLPALSEKDKADLRFGVKNGVDMIFASFVRKASDVLEIREVLGEAGKniqIIAKIENQEGVNNFDEILEATD 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 236 AIMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASG 315
Cdd:pfam00224 242 GIMVARGDLGIEIPAEEVFLAQKMLIAKCNLAGKPVITATQMLESMIYNPRPTRAEVSDVANAVLDGTDCVMLSGETAKG 321
|
330 340
....*....|....*....|...
gi 2100171583 316 EYPIEAVQMMSKIIRQVENGPDY 338
Cdd:pfam00224 322 NYPVEAVRMMHEICLEAEKALPH 344
|
|
| PRK09206 |
PRK09206 |
pyruvate kinase PykF; |
5-470 |
2.09e-127 |
|
pyruvate kinase PykF;
Pssm-ID: 181699 [Multi-domain] Cd Length: 470 Bit Score: 377.86 E-value: 2.09e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:PRK09206 2 KKTKIVCTIGPKTESEEMLTKLLDAGMNVMRLNFSHGDYAEHGQRIKNLRNVMSKTGKKAAILLDTKGPEIRTMKLEGGN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 -VQLHRGQALRLDLDPT-PGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVP 162
Cdd:PRK09206 82 dVSLKAGQTFTFTTDKSvVGNKERVAVTYEGFTADLSVGNTVLVDDGLIGMEVTAITGNEVICKVLNNGDLGENKGVNLP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 163 QAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELI----GDKAFLMAKIEKPSAVTQLREIAELSDAIM 238
Cdd:PRK09206 162 GVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVLEIREHLkahgGENIQIISKIENQEGLNNFDEILEASDGIM 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 239 VARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYP 318
Cdd:PRK09206 242 VARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 319 IEAVQMMSKIIRQVEngPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSlRAARER-PTVPILN 397
Cdd:PRK09206 322 LEAVSIMATICERTD--RVMNSRLESNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSA-RSVRKYfPDATILA 398
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 2100171583 398 LTPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAG--VPfgqPGSTNSLRIETL 470
Cdd:PRK09206 399 LTTNEKTARQLVLSKGVVPQLVKEIASTDDFYRLGKELALQSGLAQKGDVVVMVSGalVP---SGTTNTASVHVL 470
|
|
| PTZ00066 |
PTZ00066 |
pyruvate kinase; Provisional |
4-467 |
6.76e-117 |
|
pyruvate kinase; Provisional
Pssm-ID: 173361 [Multi-domain] Cd Length: 513 Bit Score: 352.53 E-value: 6.76e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 4 DKKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQL-NYPLGILMDLQGPKLRVGKFAE 82
Cdd:PTZ00066 37 QKKTHIVCTMGPACKNVETLVKLIDAGMNICRFNFSHGDHESHKKTLNNVREAAKARpNANLGILLDTKGPEIRTGFLKN 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 83 GK-VQLHRGQALRLDLDPT-PGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVN 160
Cdd:PTZ00066 117 HKpITLKEGQTLKITTDYTfLGDETCISCSYKKLPQSVKVGNIILIADGSLSCKVLEVHDDYIITKVLNNATIGERKNMN 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRD-MTFGLELGVDWVALSFVQRPEDIREARELIGDKAF---LMAKIEKPSAVTQLREIAELSDA 236
Cdd:PTZ00066 197 LPGVKVELPVIGEKDKNDiLNFAIPMGCDFIALSFVQSADDVRLCRQLLGERGRhikIIPKIENIEGLINFDEILAESDG 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 237 IMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGE 316
Cdd:PTZ00066 277 IMVARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMIKNPRPTRAESTDVANAVLDGTDCVMLSGETANGK 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 317 YPIEAVQMMSKIIRQVENGPDYQT--QLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVP 394
Cdd:PTZ00066 357 FPVEAVNIMAKICFEAETCIDYRVlyHAIHLAVPTPVSVQEAVARSAVETAEDINAKLIIALTETGNTARLISKYRPSCT 436
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2100171583 395 ILNLTPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRI 467
Cdd:PTZ00066 437 ILALSASPSVVKSLSVARGVTTYVVNSFQGTDVVIRNAIALAKERGLVESGDSAIAVHGVKEEVAGSSNLMKV 509
|
|
| PTZ00300 |
PTZ00300 |
pyruvate kinase; Provisional |
31-450 |
2.55e-98 |
|
pyruvate kinase; Provisional
Pssm-ID: 140321 [Multi-domain] Cd Length: 454 Bit Score: 303.13 E-value: 2.55e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 31 VNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGKVQLHRGQALRLDLDPT---PGDQRRV 107
Cdd:PTZ00300 1 MSVARMNFSHGSHEYHQTTINNVRQAAAELGVNIAIALDTKGPEIRTGLFVGGEAVMERGATCYVTTDPAfadKGTKDKF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 108 NLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYAD-AIDTTVLNGGELSDRKGVNVPQAVLELSPLTAKDRRDMTFGLELG 186
Cdd:PTZ00300 81 YIDYQNLSKVVRPGGYIYIDDGILILHVQSHEDEqTLKCTVTNAHTISDRRGVNLPGCDVDLPAVSAKDCADLQFGVEQG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 187 VDWVALSFVQRPEDIREARELIGDKA---FLMAKIEKPSAVTQLREIAELSDAIMVARGDLGVEVPAESVPQIQKNIISI 263
Cdd:PTZ00300 161 VDMIFASFIRSAEQVGEVRKALGAKGgdiMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 264 CRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPIEAVQMMSKIIRQVENGPDYQTQLD 343
Cdd:PTZ00300 241 CNVAGKPVICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSAVNEYVFFN 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 344 VSRP--KAEATVSDAI-SCAIRRISNVLPVAVLVnYSESGTSSLRAARERPTVPILNLTPNLQTARRLTVAWGVHSVVND 420
Cdd:PTZ00300 321 SIKKlqPIPMSAEEAVcSSAVNSVYETKAKALVV-LSNTGRSARLVAKYRPNCPIVCVTTRLQTCRQLNITQGVESVFFD 399
|
410 420 430
....*....|....*....|....*....|....*
gi 2100171583 421 RLR-----QVDEVCSTALEIAQAQGMAQRGDTLLI 450
Cdd:PTZ00300 400 AERlghdeGKEQRVAMGVGFAKSKGYVQSGDLMVV 434
|
|
| PLN02461 |
PLN02461 |
Probable pyruvate kinase |
5-446 |
1.03e-97 |
|
Probable pyruvate kinase
Pssm-ID: 215255 [Multi-domain] Cd Length: 511 Bit Score: 303.05 E-value: 1.03e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGK 84
Cdd:PLN02461 21 PKTKIVCTLGPASRSVPMLEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMANTGILCAVMLDTKGPEIRTGFLKDGK 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 85 -VQLHRGQALRLDLDPT-PGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVT--KYADAIDTTVLNGGELSDRKGVN 160
Cdd:PLN02461 101 pVQLKQGQEITITTDYSiKGDENMIAMSYKKLAVDVKPGSVILCADGTITLTVLScdVEAGTVRCRCENSAMLGERKNVN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRD-MTFGLELGVDWVALSFVQRPEDIREARELIGDKA---FLMAKIEKPSAVTQLREIAELSDA 236
Cdd:PLN02461 181 LPGVVVDLPTLTEKDKEDiLQWGVPNKIDFIALSFVRKGSDLVEVRKVLGEHAksiLLISKVENQEGLDNFDDILAESDA 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 237 IMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGE 316
Cdd:PLN02461 261 FMVARGDLGMEIPIEKIFLAQKMMIYKCNLAGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAGA 340
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 317 YPIEAVQMMSKIIRQVENGPDY-----QTQLDVSRPKA--EATVSDAISCAirrisNVLPVAVLVNYSESGTSSLRAARE 389
Cdd:PLN02461 341 YPELAVKTMARICREAEASLDYgalfkEIMRSAPLPMSplESLASSAVRTA-----NKVKASLIVVLTRGGTTARLVAKY 415
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2100171583 390 RPTVPILNL-TPNLQT------------ARRLTVAWGVHSVV-NDRLRQVD-----EVCSTALEIAQAQGMAQRGD 446
Cdd:PLN02461 416 RPAVPILSVvVPEITTdsfdwscsdeapARHSLIYRGLIPVLaEGSAKATDsesteEILEAAIEHAKKKGLCKPGD 491
|
|
| PRK06739 |
PRK06739 |
pyruvate kinase; Validated |
1-328 |
7.06e-87 |
|
pyruvate kinase; Validated
Pssm-ID: 180676 [Multi-domain] Cd Length: 352 Bit Score: 269.89 E-value: 7.06e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 1 MTPDKkvkiLATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQryqwIREVERQLNYPLGILMDLQGPKLRVGKF 80
Cdd:PRK06739 1 MTIDR----ICTIGPASNNKETLAQLINNGMKIVRLNLSHGTHESHKD----IIRLVKSLDDSIKILGDVQGPKIRLGEI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 81 AEGKVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVN 160
Cdd:PRK06739 73 KGEQITLQAGDSFILHTQPVTGSSTEASVDYEGIANDVKVGSRILMNDGEVELIVEKVSTDKIETKVKTGGNISSHKGVN 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 161 VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF----LMAKIEKPSAVTQLREIAELSDA 236
Cdd:PRK06739 153 LPGAIVRLPAITEKDKKDIQFLLEEDVDFIACSFVRKPSHIKEIRDFIQQYKEtspnLIAKIETMEAIENFQDICKEADG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 237 IMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGE 316
Cdd:PRK06739 233 IMIARGDLGVELPYQFIPLLQKMMIQECNRTNTYVITATQMLQSMVDHSIPTRAEVTDVFQAVLDGTNAVMLSAESASGE 312
|
330
....*....|..
gi 2100171583 317 YPIEAVQMMSKI 328
Cdd:PRK06739 313 HPIESVSTLRLV 324
|
|
| PLN02623 |
PLN02623 |
pyruvate kinase |
5-467 |
2.97e-86 |
|
pyruvate kinase
Pssm-ID: 215334 [Multi-domain] Cd Length: 581 Bit Score: 275.65 E-value: 2.97e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLN-YPLGILMDLQGPKLRVGKFAEg 83
Cdd:PLN02623 110 RKTKIVCTIGPSTNTREMIWKLAEAGMNVARLNMSHGDHASHQKVIDLVKEYNAQSKdNVIAIMLDTKGPEVRSGDLPQ- 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 84 KVQLHRGQALRLDLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADAIDTTVLNGGELSDRKGVNVPQ 163
Cdd:PLN02623 189 PIMLEEGQEFTFTIKRGVSTEDCVSVNYDDFVNDVEVGDMLLVDGGMMSLAVKSKTSDSVKCEVVDGGELKSRRHLNVRG 268
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 164 AVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKA---FLMAKIEKPSAVTQLREIAELSDAIMVA 240
Cdd:PLN02623 269 KSATLPSITEKDWEDIKFGVENKVDFYAVSFVKDAQVVHELKDYLKSCNadiHVIVKIESADSIPNLHSIITASDGAMVA 348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 241 RGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPIE 320
Cdd:PLN02623 349 RGDLGAELPIEEVPLLQEEIIRRCRSMGKPVIVATNMLESMIVHPTPTRAEVSDIAIAVREGADAVMLSGETAHGKFPLK 428
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 321 AVQMMSKIIRQVENGPDYQTQLDVSRPKAEATVSDAISCAIRRISNVLPVAVLVnYSESGTSSLRAARERPTVPILNLTP 400
Cdd:PLN02623 429 AVKVMHTVALRTEATLPEGTTPPNLGQAFKNHMSEMFAFHATMMANTLGTSIIV-FTRTGFMAILLSHYRPSGTIFAFTN 507
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2100171583 401 NLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGD--TLLITAGVPFGQPGSTNSLRI 467
Cdd:PLN02623 508 EKRIQQRLALYQGVCPIYMQFSDDAEETFARALSLLLNKGMVKEGEevALVQSGRQPIWRSESTHHIQV 576
|
|
| PLN02762 |
PLN02762 |
pyruvate kinase complex alpha subunit |
5-450 |
1.34e-78 |
|
pyruvate kinase complex alpha subunit
Pssm-ID: 215407 [Multi-domain] Cd Length: 509 Bit Score: 253.51 E-value: 1.34e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 5 KKVKILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRyqwIREVeRQLN----YPLGILMDLQGPKLRVGKF 80
Cdd:PLN02762 25 RRTKLVCTIGPACCGFEQLEALAMGGMNVARLNMCHGTREWHRDV---IRRV-RRLNeekgFAVAVMMDTEGSEIHMGDL 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 81 -AEGKVQLHRGQALRLDLdptpgdqRRVNLPHPE--IIAALEP-------GMDLLLDDGKLRLRVVTKYADAIDTTVLNG 150
Cdd:PLN02762 101 gGASSAKAEDGEEWTFTV-------RKFDGSRPEftIQVNYDGfaedvkvGDELVVDGGMVRFEVIEKIGPDVKCKCTDP 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 151 GELSDRKGVN-------VPQAVLELSPLTAKDRRDMTFGLELGVDWVALSFVQRPEDIREARELIGDKAF-----LMAKI 218
Cdd:PLN02762 174 GLLLPRANLTfwrdgslVRERNAMLPTISSKDWLDIDFGISEGVDFIAVSFVKSAEVIKHLKSYIAARSRdsdigVIAKI 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 219 EKPSAVTQLREIAELSDAIMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANA 298
Cdd:PLN02762 254 ESLDSLKNLEEIIRASDGAMVARGDLGAQIPLEQVPSVQEKIVRLCRQLNKPVIVASQLLESMIEYPTPTRAEVADVSEA 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 299 VAEGADAVMLSAETASGEYPIEAVQMMSKIIRQVEN-GPDYQTQLDVSRPKAEATVSDAIS-----CAIrRISNVLPVAV 372
Cdd:PLN02762 334 VRQRADALMLSGESAMGLYPEKALSVLRSVSLRMELwSREEKRHEALELPQLSSSLSDRISeeicnSAA-KMANNLGVDA 412
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 2100171583 373 LVNYSESGTSSLRAARERPTVPILNLTPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALEIAQAQGMAQRGDTLLI 450
Cdd:PLN02762 413 IFVYTKHGHMASLLSRNRPDCPIFAFTDTTSVRRRLNLQWGLIPFRLDFSDDMESNLNKTFSLLKARGMIKSGDLVIA 490
|
|
| PLN02765 |
PLN02765 |
pyruvate kinase |
8-450 |
2.05e-62 |
|
pyruvate kinase
Pssm-ID: 215409 [Multi-domain] Cd Length: 526 Bit Score: 211.45 E-value: 2.05e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 8 KILATLGPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAEGKVQL 87
Cdd:PLN02765 31 KIVGTLGPKSRSVEVIEACLKAGMSVARFDFSWGDAEYHQETLENLKIAVKNTKKLCAVMLDTVGPELQVINKTEKPISL 110
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 88 HRGQALRLDLDPTPGDQRRVnLP--HPEIIAALEPGMDLLL--------DDGKLRLRVVTKYADAIDTTVLNGGELSdrk 157
Cdd:PLN02765 111 KAGNTVTLTPDQSKEASSEV-LPinFPGLAKAVKPGDTIFVgqylftgsETTSVWLEVDEVKGDDVVCTVKNSATLA--- 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 158 G----VNVPQAVLELSPLTAKDRRDM-TFGLELGVDWVALSFVQRPEDIREARELIGDKAF----LMAKIEKPSAVTQLR 228
Cdd:PLN02765 187 GslftLHVSQVRIDLPTLSEKDKEVIsTWGVPNKIDFLSLSYTRHAEDVREAREFLSSLGLsqtqIFAKIENVEGLTHFD 266
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 229 EIAELSDAIMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVaTQMLESMRFSPAPTRAEVTDVANAVAEGADAVML 308
Cdd:PLN02765 267 EILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPAVV-TRVVDSMTDNLRPTRAEATDVANAVLDGADAILL 345
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 309 SAETASGEYPIEAVQMMSKIIRQVENGPDYQTQLD-----VSRP--KAEATVSDAISCAIRrisnvLPVAVLVNYSESGT 381
Cdd:PLN02765 346 GAETLRGLYPVETISTVGRICAEAEKVFNQDLYFKktvkyVGEPmsHLESIASSAVRAAIK-----VKASVIIVFTSSGR 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 382 SSLRAARERPTVPILNLT-PNLQT------------ARRLTVAWGVHSVVNDRLRQVDEVCST-------ALEIAQAQGM 441
Cdd:PLN02765 421 AARLIAKYRPTMPVLSVViPRLKTnqlkwsftgafqARQCLIVRGLFPMLADPRHSAESTSATnesvlkvALDHGKAAGV 500
|
....*....
gi 2100171583 442 AQRGDTLLI 450
Cdd:PLN02765 501 IKSHDRVVV 509
|
|
| PRK08187 |
PRK08187 |
pyruvate kinase; Validated |
7-330 |
1.16e-59 |
|
pyruvate kinase; Validated
Pssm-ID: 236178 Cd Length: 493 Bit Score: 203.32 E-value: 1.16e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 7 VKILATL-GPATDGIEDIRELVQAGVNIFRLNFSHGDHADHAQRYQWIREVERQLNYPLGILMDLQGPKLRVGKFAE--G 83
Cdd:PRK08187 135 TRIMVTLpSEAADDPDFVLRLAERGMDCARINCAHDDPAAWQAMIGHLRQAERATGRRCKILMDLAGPKIRTGAVAGplG 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 84 KVQLHRGQALRL----DLDPTPGDQRRVNLPHPEIIAALEPGMDLLLDDGKLRLRVVTKYADA----IDTTVLNGGELSD 155
Cdd:PRK08187 215 KTRLYTGDRLALvaqgPPRRIDEEHFQVTCTLPEILARLAVGARVWIDDGKLGARVERVGPGGalleVTHARPKGLKLKP 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 156 RKGVNVPQAVLELSPLTAKDRRDMTFGLElGVDWVALSFVQRPEDIR------EARELIG-DKAFLMAKIEKPSAVTQLR 228
Cdd:PRK08187 295 EKGLNFPDTALDLPALTEKDRADLDFVAR-HADLVGYSFVQSPGDVEalqaalAARRPDDwRKLGLVLKIETPRAVANLP 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 229 EI-----AELSDAIMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVanAVAEGA 303
Cdd:PRK08187 374 ELivqaaGRQPFGVMIARGDLAVEIGFERLAEMQEEILWLCEAAHVPVIWATQVLEGLVKKGLPSRAEMTDA--AMAARA 451
|
330 340
....*....|....*....|....*..
gi 2100171583 304 DAVMLSaetaSGEYPIEAVQMMSKIIR 330
Cdd:PRK08187 452 ECVMLN----KGPYLVEAVTFLDDLLA 474
|
|
| PykA2 |
COG3848 |
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms]; |
263-469 |
1.22e-47 |
|
Phosphohistidine swiveling domain of PEP-utilizing enzymes [Signal transduction mechanisms];
Pssm-ID: 443058 Cd Length: 321 Bit Score: 166.61 E-value: 1.22e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 263 ICRQLGKPVVVATQMLESMRFSPAPTRAEVTDVANAVAEGADAVMLSAETASGEYPIEAVQMMSKIIRQVENGPDYQTQL 342
Cdd:COG3848 1 KCNAAGKPVITATQMLDSMMRNPRPTRAEAADVANAIFDGTDAIMLSGETAAGKYPVEAVVTMVRIAERAEEDLEYREQR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 343 DVSRPKAEATVSDAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLTPNLQTARRLTVAWGVHSVVNDRL 422
Cdd:COG3848 81 VPRAKESSTTITDAISHAVATTAADLGAAAIITATESGATARMVSKYRPKAPIIAVTPSERVARQLSLVWGVYPLLVEES 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 2100171583 423 RQVDEVCSTALEIAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRIET 469
Cdd:COG3848 161 ASTDEMFAVAVALALEAGLVKDGDLVVITAGVPVGVSGTTNLLKVHV 207
|
|
| PRK14725 |
PRK14725 |
pyruvate kinase; Provisional |
74-333 |
1.81e-43 |
|
pyruvate kinase; Provisional
Pssm-ID: 237804 Cd Length: 608 Bit Score: 161.66 E-value: 1.81e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 74 KLRVGKFA--EGKVQLHRGQALRLDLDPTPGD--QRRVNLPH-----PEIIAALEPGMDLLLDDGKLRLRVVTKYADAID 144
Cdd:PRK14725 320 STRVGGLPpvEQKLRLKVGDRLVLTRDDAPGDpaQGDAPPARisctlPEAFRAARVGERVWFDDGKIGAVVVKVEADEVE 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 145 TTVLNGGE----LSDRKGVNVPQAVLELSPLTAKDRRDMTFGLELGvDWVALSFVQRPEDIREARELI----GDKAFLMA 216
Cdd:PRK14725 400 LRITHARPggskLKAGKGINLPDSHLPLPALTDKDLEDLAFVAKHA-DIVALSFVRSPEDVRLLLDALeklgADDLGVVL 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 217 KIEKPSAVTQLREIaeLSDA-------IMVARGDLGVEVPAESVPQIQKNIISICRQLGKPVVVATQMLESMRFSPAPTR 289
Cdd:PRK14725 479 KIETRRAFENLPRI--LLEAmrhprfgVMIARGDLAVEVGFERLAEVQEEILWLCEAAHVPVIWATQVLESLAKKGLPSR 556
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2100171583 290 AEVTDVanAVAEGADAVMLSaetaSGEYPIEAVQMMSKIIRQVE 333
Cdd:PRK14725 557 AEITDA--AMALRAECVMLN----KGPHIVEAVRVLDDILRRME 594
|
|
| PK_C |
pfam02887 |
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is ... |
355-467 |
1.66e-34 |
|
Pyruvate kinase, alpha/beta domain; As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Pssm-ID: 460738 [Multi-domain] Cd Length: 114 Bit Score: 124.90 E-value: 1.66e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2100171583 355 DAISCAIRRISNVLPVAVLVNYSESGTSSLRAARERPTVPILNLTPNLQTARRLTVAWGVHSVVNDRLRQVDEVCSTALE 434
Cdd:pfam02887 1 EAIAHAAVEAAEELGAKAIVVLTESGYTARLISRYRPGVPIIAVTPNELTARQLALYWGVYPVLFDEAETTDEMLRRAVK 80
|
90 100 110
....*....|....*....|....*....|...
gi 2100171583 435 IAQAQGMAQRGDTLLITAGVPFGQPGSTNSLRI 467
Cdd:pfam02887 81 VAKEAGLVKKGDLVVITAGVPFGVSGTTNTLKV 113
|
|
| |
